Faculty Profiles - MORIOKA Hiroshi

Papers - MORIOKA Hiroshi

Division display 41 - 57 of about 57 ／ All the affair displays >>

Laryngeal Kaposi's Sarcoma Complicated by the Immune Reconstitution Inflammatory Syndrome in an HIV-infected Patient. Open Access

Hirofumi Kato, Naoki Yanagisawa, Hiroshi Morioka, Shugo Sasaki, Noritaka Sekiya, Akihiko Suganuma, Akifumi Imamura, Atsushi Ajisawa

Internal medicine (Tokyo, Japan) Vol. 55 ( 8 ) page： 1001 - 1005 2016

Publishing type：Research paper (scientific journal)

We herein report a case of laryngeal Kaposi's sarcoma (KS) complicated by immune reconstitution inflammatory syndrome in a human immunodeficiency virus (HIV)-infected patient. The patient initially presented with KS involving the larynx, which was successfully treated with pegylated liposomal doxorubicin (PLD) and antiretroviral therapy (ART). PLD was discontinued after 2 courses because of a marked clinical improvement; however, the patient experienced progressive odynophagia and dyspnea 2 months after the initiation of ART. Laryngoscopy revealed a severely swollen, inflamed epiglottis. The readministration of PLD was successful, and the patient was thereafter discharged without any subsequent complications.

DOI： 10.2169/internalmedicine.55.5813

Disseminated Mycobacterium abscessus Infection Following Septic Arthritis: A Case Report and Review of the Literature. International journal Open Access

Shoichi Fukui, Noritaka Sekiya, Yasunobu Takizawa, Hiroshi Morioka, Hirofumi Kato, Akio Aono, Kinuyo Chikamatsu, Satoshi Mitarai, Satomi Kobayashi, Satoshi Kamei, Keigo Setoguchi

Medicine Vol. 94 ( 21 ) page： e861 2015.5

Publishing type：Research paper (scientific journal)

Mycobacterium abscessus is a rapidly growing mycobacterium found mainly in patients with respiratory or cutaneous infections, but it rarely causes disseminated infections. Little is known about the clinical characteristics, treatment, and prognosis of disseminated M abscessus infection. A 75-year-old Japanese woman who had been treated for 17 years with a corticosteroid for antisynthetase syndrome with antithreonyl-tRNA synthetase antibody developed swelling of her right elbow. X-ray of her right elbow joint showed osteolysis, and magnetic resonance imaging revealed fluid in her right elbow joint. M abscessus grew in joint fluid and blood cultures. She was diagnosed with a disseminated M abscessus infection following septic arthritis. Antimicrobial treatment by clarithromycin, amikacin, and imipenem/cilastatin combined with surgical debridement was administered. Although blood and joint fluid cultures became negative 1 week later, the patient died at 6 weeks from starting antimicrobial treatment. We reviewed 34 cases of disseminated M abscessus infections from the literature. Most of the patients had immunosuppressive backgrounds such as transplantation, use of immunosuppressive agents, hematological malignancy, and end stage renal disease. The duration from onset of symptoms to diagnosis was over 3 months in half of the cases. All fatal cases had positive blood cultures or use of immunosuppressive agents. Clinicians should bear in mind that mycobacterial infections including M abscessus are one of the differential diagnoses in patients with subacute arthritis and soft tissue infections.

DOI： 10.1097/MD.0000000000000861

A型肝炎ワクチン(エイムゲンとHavrix)接種後の抗体価と互換性に関する検討

菊池均, 宮津光伸, 永田俊人, 後藤泰浩, 山本悦子, 森岡悠, 佐藤好隆

日本渡航医学会誌 = Journal of the Japanese Society of Travel and Health Vol. 9 ( 1 ) page： 48 - 50 2015

P0578-22-AM 注射用抗菌薬届出システムの構築と適正使用に向けた介入方法の検討(感染制御(その他)1,ポスター発表,一般演題,医療薬学の進歩と未来-次の四半世紀に向けて-)

加藤善章, 八木哲也, 山田清文, 山本雅人, 稲垣孝行, 手塚宜行, 森岡悠, 平林亜希, 井口光孝, 加藤大三, 冨田ゆうか

日本医療薬学会年会講演要旨集 Vol. 25 ( 0 ) 2015

Evaluation of HIV-infected Patients Suspected as Having HIV-associated Neurocognitive Disorders

MORIOKA Hiroshi, KISHIDA Shuji, IMAMURA Akifumi, SEKIYA Noritaka, YANAGISAWA Naoki, SUGANUMA Akihiko, AJISAWA Atsushi

Kansenshogaku Zasshi Vol. 88 ( 2 ) page： 141 - 8 2014.3

Publishing type：Research paper (scientific journal) Publisher：The Japanese Association for Infectious Diseases

Background：HIV-associated neurocognitive disorders (HAND) have emerged as a problem among HIV-infected individuals in the era of antiretroviral therapy. However, there are insufficient data on HAND regarding its prevalence and clinical features in Japan. Methods：A test battery composed of eight neuropsycological tests proposed by the Ministry of Health,Labour and Welfare (MHLW test battery) was applied to assess 30 subjects at Tokyo Metropolitan Komagome Hospital. Among them, 5 subjects were excluded due to central nervous system complications. The background of each patient along with the results of head magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis and neuropsychological tests were compared to each HAND category. In addition, the clinical utility of a combination of neuropsychological tests as an abbreviated test battery of HAND was evaluated. Results：A total of 19 (76％) subjects were diagnosed as having a HAND. Among them, HIV-associated dementia, mild neurocognitive disorders and asymptomatic neurocognitive disorders were diagnosed in 7, 8,and 4 subjects, respectively. Neither the patientʼs background nor the results of the head MRI and CSF analysis showed relevance to disease severity. The conventional International HIV Dementia Scale with the Digit Symbol Substitute Test was capable of detecting 94.7％cases of HAND. Conclusions：Most HIV-infected subjects clinically suspected as having neurocognitive disorders were diagnosed as having a HAND. Neuropsychological tests of the MHLW test battery were in some part useful to diagnose HAND. However, more precise neuropsychological tests are warranted to screen and diagnose HAND, based on the current criteria.

DOI： 10.11150/kansenshogakuzasshi.88.141

Scopus

PubMed

CiNii Research

Bilateral Facial Nerve Palsy and Appendicitis Occurring during Acute Retroviral Syndrome Open Access

Morioka Hiroshi, Sakamoto Naoya, Iwabuchi Sentaro, Ohnishi Kenji

INTERNAL MEDICINE Vol. 53 ( 2 ) page： 155 - 158 2014

Publishing type：Research paper (scientific journal) Publisher：Internal Medicine

We herein report the case of 41-year-old homosexual man who presented to our hospital with typical acute retroviral syndrome. Complications of bilateral facial nerve palsy and appendicitis appeared eight days after admission. The bilateral facial nerve palsy spontaneously recovered one month later; however, the appendicitis required surgical intervention. To our knowledge, this is the first reported case of appendicitis related to acute retroviral syndrome.

DOI： 10.2169/internalmedicine.53.0636

神経心理検査で改善が示唆されたHIV-associated dementiaの1例

森岡悠, 今村顕史

HIV感染症とAIDSの治療 Vol. 5 ( 1 ) page： 46 - 48 2014

Necrotizing Fasciitis after a Cat Bite : A Case Report

HOSODA Tomohiro, YANAGISAWA Naoki, MORIOKA Hiroshi, SUGANUMA Akihiko, IMAMURA Akifumi, AJISAWA Atsushi

Kansenshogaku Zasshi Vol. 87 ( 2 ) page： 211 - 4 2013.3

Publishing type：Research paper (scientific journal) Publisher：The Japanese Association for Infectious Diseases

We report on a previously healthy 56-year-old woman who was referred to our hospital with fever and progressive left foot pain. She had been bitten by a cat 7 days previously, and cephalosporins had been prescribed for treatment. However, her clinical symptoms deteriorated, and physical examination on admission was compatible with necrotizing fasciitis. Treatment with ampicillin-sulbactam and clindamycin was initiated. In addition, immediate surgical debridement was performed, resulting in therapeutic success. Culture of the necrotizing tissue grew multiple organisms, including Pasteurella multocida and Bacteroides caccae. Administration of appropriate antibiotics after a cat bite is essential for the prevention of potentially fatal complications.

DOI： 10.11150/kansenshogakuzasshi.87.211

PubMed

CiNii Research

Re-expansion pulmonary edema: evaluation of risk factors in 173 episodes of spontaneous pneumothorax. International journal

Hiroshi Morioka, Kazuto Takada, Shuuichi Matsumoto, Eiji Kojima, Susumu Iwata, Shoutaro Okachi

Respiratory investigation Vol. 51 ( 1 ) page： 35 - 9 2013.3

Publishing type：Research paper (scientific journal)

BACKGROUND: The precise incidence and clinical features of re-expansion pulmonary edema (RPE) are unclear, and they vary among reports. In this study, we assessed the incidence, risk factors, and outcomes of patients with RPE over a 3-yr period in a general hospital, with the goal of proposing a primary intervention for pneumothorax. METHODS: We retrospectively reviewed records of inpatients with spontaneous pneumothorax treated by tube thoracostomy between October 2007 and December 2010. RESULTS: A total of 173 episodes of spontaneous pneumothorax occurred in 156 patients. The incidence of RPE was 27/173 (15.6%). Symptom duration and pneumothorax size were significant risk factors for RPE, and the occurrence of RPE was independent of primary treatment of spontaneous pneumothorax. Among the patients with RPE, 18 (67%) were symptomatic. Five patients (18.5%) were treated with temporary oxygen, however, 21 patients (78%) did not need any treatment. All patients survived and none required mechanical ventilation. The occurrence of RPE did not influence the clinical outcome. CONCLUSIONS: The risk of developing RPE increases with an increased duration or size of pneumothorax. Our results suggest that the methods of primary intervention, including prompt suction, do not affect the onset of RPE. Close observation is always required regardless of the intervention because of the potentially fatal complications.

DOI： 10.1016/j.resinv.2012.09.003

PubMed

Bilateral Emphysematous Pyelonephritis with a Splenic Abscess Open Access

Morioka Hiroshi, Yanagisawa Naoki, Suganuma Akihiko, Imamura Akifumi, Ajisawa Atsushi

INTERNAL MEDICINE Vol. 52 ( 1 ) page： 147 - 150 2013

Publishing type：Research paper (scientific journal) Publisher：一般社団法人日本内科学会

The case of a 66-year-old woman with untreated diabetes mellitus who was admitted to our hospital with a fever, hypotension and an altered mental status is herein reported. Computed tomography revealed bilateral emphysematous pyelonephritis along with a splenic abscess. Blood and urine cultures grew Escherichia coli. Treatment with systemic antibiotics combined with the insertion of percutaneous and renoureteral catheters was successful. The patient was discharged and completed treatment without developing any subsequent complications.

DOI： 10.2169/internalmedicine.52.8302

Paradoxical Infarct in Tuberculous Meningitis: A Case Report Open Access

Morioka Hiroshi, Matsumoto Shuuichi, Kojima Eiji, Takada Kazuto, Iwata Susumu, Okachi Shoutaro

INTERNAL MEDICINE Vol. 51 ( 8 ) page： 949 - 951 2012

Publishing type：Research paper (scientific journal) Publisher：一般社団法人日本内科学会

We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.

DOI： 10.2169/internalmedicine.51.6830

Prospective evaluation of the relationship between acute exacerbations of COPD and gastroesophageal reflux disease diagnosed by questionnaire. International journal Open Access

Kazuto Takada, Shuuichi Matsumoto, Eiji Kojima, Susumu Iwata, Shoutarou Okachi, Kiyoko Ninomiya, Hiroshi Morioka, Kentarou Tanaka, Yasunori Enomoto

Respiratory medicine Vol. 105 ( 10 ) page： 1531 - 1536 2011.10

Publishing type：Research paper (scientific journal)

BACKGROUND: Little is known about the relationship between acute exacerbations of COPD (AECOPD) and gastroesophageal reflux disease (GERD). The aim of this study was to investigate the effects on AECOPD of GERD diagnosed by a questionnaire. METHODS: The subjects were 221 consecutive patients with stable COPD who were evaluated using the Frequency Scale for Symptoms of GERD (FSSG) and a prospective survey of AECOPD for one year. Patients taking drugs for acid suppression were excluded. The association between the frequency of AECOPD and the presence of GERD or FSSG score was examined. RESULTS: Based on the FSSG, the prevalence of GERD was 26.7%. AECOPD and hospitalization due to AECOPD were significantly more frequent in patients with GERD than in those without GERD, with crude relative risks of 3.42 and 3.66, respectively. Multivariate analyses showed that GERD and COPD stage IV were significant predictors of hospitalization due to AECOPD, independent of respiratory therapies or patient characteristics. The severity of GERD symptoms, as measured by the FSSG score, was significantly correlated with the frequencies of AECOPD and hospitalization due to AECOPD. Similar correlations were seen for the FSSG subscores for acid reflux and gastric dysmotility. CONCLUSIONS: This prospective cohort study showed that GERD appears to be a predictive factor for hospitalization due to AECOPD and that severer GERD symptoms may be associated with more frequent AECOPD. Thus, further studies are warranted to evaluate the preventive effect of the therapy for GERD on AECOPD.

DOI： 10.1016/j.rmed.2011.03.009

Web of Science

PubMed

Case report: A case of pneumocystis pneumonia after etanercept therapy

Vol. 108 ( 3 ) page： 555 - 557 2011.9

A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman

MORIOKA Hiroshi, MATSUMOTO Shuuichi, KOJIMA Eiji, TAKADA Kazuto, SHIZU Masato, OKACHI Shoutarou

Vol. 49 ( 1 ) page： 57 - 61 2011.1

[A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman]. Open Access

Morioka H, Matsumoto S, Kojima E, Takada K, Shizu M, Okachi S

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Vol. 49 ( 1 ) page： 57 - 61 2011.1

[A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman]. Open Access

Morioka H., Matsumoto S., Kojima E., Takada K., Shizu M., Okachi S.

Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society Vol. 49 ( 1 ) page： 57 - 61 2011.1

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society

We describe a case of fulminant community-acquired Acinetobacter baumannii pneumonia. A 68-year-old woman, who had no past medical history, was admitted with septic shock and pneumonia of left lower lobe. Despite intensive treatment she died on day 3 after admission. To the best of our knowledge, this is the 4th report of community-acquired Acinetobacter pneumonia in Japan and the 1st report in a healthy patient. We report a case of Acinetobacter pneumonia and discuss the clinical characteristics of the community-acquired type compared with the hospital-acquired type.

DOI： 10.11389/jjars.49010057

Open Access

Scopus

P2-09-3 FeNO高値の気管支喘息患者に対するブデゾニド/ホルモテロール配合薬による薬物療法の効果と安全性(P2-09 成人喘息5,ポスターセッション,第23回日本アレルギー学会春季臨床大会) Open Access

岩田晋, 後藤大揮, 清水隆宏, 松本修一, 小島英嗣, 高田和外, 岡地祥太郎, 二宮記代子, 森岡悠, 田中健太郎, 榎本泰典

アレルギー Vol. 60 ( 3 ) 2011

　 PREV - NEXT 　

<MORIOKA Hiroshi>

Papers - MORIOKA Hiroshi