Faculty Profiles - MORIOKA Hiroshi

Papers - MORIOKA Hiroshi

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Paradoxical Infarct in Tuberculous Meningitis: A Case Report

Morioka Hiroshi, Matsumoto Shuuichi, Kojima Eiji, Takada Kazuto, Iwata Susumu, Okachi Shoutaro

INTERNAL MEDICINE Vol. 51 ( 8 ) page： 949 - 951 2012

Publishing type：Research paper (scientific journal) Publisher：一般社団法人日本内科学会

We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.<br>

DOI： 10.2169/internalmedicine.51.6830

Web of Science

PubMed

Prospective evaluation of the relationship between acute exacerbations of COPD and gastroesophageal reflux disease diagnosed by questionnaire. International journal

Kazuto Takada, Shuuichi Matsumoto, Eiji Kojima, Susumu Iwata, Shoutarou Okachi, Kiyoko Ninomiya, Hiroshi Morioka, Kentarou Tanaka, Yasunori Enomoto

Respiratory medicine Vol. 105 ( 10 ) page： 1531 - 1536 2011.10

Publishing type：Research paper (scientific journal)

BACKGROUND: Little is known about the relationship between acute exacerbations of COPD (AECOPD) and gastroesophageal reflux disease (GERD). The aim of this study was to investigate the effects on AECOPD of GERD diagnosed by a questionnaire. METHODS: The subjects were 221 consecutive patients with stable COPD who were evaluated using the Frequency Scale for Symptoms of GERD (FSSG) and a prospective survey of AECOPD for one year. Patients taking drugs for acid suppression were excluded. The association between the frequency of AECOPD and the presence of GERD or FSSG score was examined. RESULTS: Based on the FSSG, the prevalence of GERD was 26.7%. AECOPD and hospitalization due to AECOPD were significantly more frequent in patients with GERD than in those without GERD, with crude relative risks of 3.42 and 3.66, respectively. Multivariate analyses showed that GERD and COPD stage IV were significant predictors of hospitalization due to AECOPD, independent of respiratory therapies or patient characteristics. The severity of GERD symptoms, as measured by the FSSG score, was significantly correlated with the frequencies of AECOPD and hospitalization due to AECOPD. Similar correlations were seen for the FSSG subscores for acid reflux and gastric dysmotility. CONCLUSIONS: This prospective cohort study showed that GERD appears to be a predictive factor for hospitalization due to AECOPD and that severer GERD symptoms may be associated with more frequent AECOPD. Thus, further studies are warranted to evaluate the preventive effect of the therapy for GERD on AECOPD.

DOI： 10.1016/j.rmed.2011.03.009

Web of Science

PubMed

Case report: A case of pneumocystis pneumonia after etanercept therapy

Vol. 108 ( 3 ) page： 555 - 557 2011.9

A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman

MORIOKA Hiroshi, MATSUMOTO Shuuichi, KOJIMA Eiji, TAKADA Kazuto, SHIZU Masato, OKACHI Shoutarou

Vol. 49 ( 1 ) page： 57 - 61 2011.1

[A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman].

Morioka H, Matsumoto S, Kojima E, Takada K, Shizu M, Okachi S

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Vol. 49 ( 1 ) page： 57 - 61 2011.1

[A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman].

Morioka H., Matsumoto S., Kojima E., Takada K., Shizu M., Okachi S.

Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society Vol. 49 ( 1 ) page： 57 - 61 2011.1

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society

We describe a case of fulminant community-acquired Acinetobacter baumannii pneumonia. A 68-year-old woman, who had no past medical history, was admitted with septic shock and pneumonia of left lower lobe. Despite intensive treatment she died on day 3 after admission. To the best of our knowledge, this is the 4th report of community-acquired Acinetobacter pneumonia in Japan and the 1st report in a healthy patient. We report a case of Acinetobacter pneumonia and discuss the clinical characteristics of the community-acquired type compared with the hospital-acquired type.

Scopus

P2-09-3 FeNO高値の気管支喘息患者に対するブデゾニド/ホルモテロール配合薬による薬物療法の効果と安全性(P2-09 成人喘息5,ポスターセッション,第23回日本アレルギー学会春季臨床大会)

岩田晋, 後藤大揮, 清水隆宏, 松本修一, 小島英嗣, 高田和外, 岡地祥太郎, 二宮記代子, 森岡悠, 田中健太郎, 榎本泰典

アレルギー Vol. 60 ( 3 ) 2011

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