担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.anl.2023.10.004

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jiac.2023.12.015.

その他リンク： https://www.sciencedirect.com/science/article/pii/S1341321X24000023?via%3Dihub

担当区分：責任著者   掲載種別：研究論文（学術雑誌）  

担当区分：責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）  

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.2169/internalmedicine.1754-23

記述言語：日本語   掲載種別：研究論文（学術雑誌）  

Web of Science

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Journal of Infection and Chemotherapy  

A 93-year-old woman was diagnosed with Lysinibacillus fusiformis bacteremia complicated with coma blisters. Initial gram staining for L. fusiformis indicated the presence of gram-negative rods; however, subsequent staining of colonies from Mueller-Hinton agar revealed the presence of gram-positive and gram-negative rods with spherical endospores, and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (VITEK ® MS and microflex® LT/SH) definitively identified the organism as L. fusiformis. The two-week administration of piperacillin/tazobactam and ampicillin resulted in an improvement of the patient's general condition, and the skin lesions gradually improved.

DOI： 10.1016/j.jiac.2021.10.030

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記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：International Journal of Infectious Diseases  

DOI： 10.1016/j.ijid.2021.10.042

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担当区分：筆頭著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

その他リンク： https://pubmed.ncbi.nlm.nih.gov/34647007/

掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本内科学会  

<p>We herein report a 59-year-old woman with a 2-year history of chronic bursitis of the hand who took 50 mg/day prednisolone for several autoimmune diseases. <i>Mycobacteroides abscessus</i> subsp. <i>massiliense</i> was isolated from the abscess and blood culture. Combination therapy (imipenem/cilastatin, amikacin, and clarithromycin) was administered for a month. Two months later, <i>M. massiliense</i> was detected from a blood culture again, and disseminated lesions were found. Clarithromycin and sitafloxacin were administered following eight weeks of the same regimen. Six months after the diagnosis, <i>M. massiliense</i> was isolated from a blood culture, and she expired due to multiple organ failure. </p>

DOI： 10.2169/internalmedicine.6189-20

PubMed

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Internal Medicine  

Nontyphoidal Salmonella is a common cause of bacterial gastroenteritis, occasionally causing bacteremia. We herein report the case of an 80-year-old man who presented with bacteremia and pre-renal acute kidney injury (AKI) secondary to diarrhea caused by nontyphoidal Salmonella. Despite AKI improvement on fluid administration, some serological abnormalities, such as hypokalemia, hypophosphatemia, and hypouricemia, and abnormal urinary findings emerged, including renal glycosuria and aminoaciduria. Fractional excretion of phosphate and uric acid was increased, suggesting that the serological and urinary abnormalities may have arisen from Fanconi syndrome. Physicians should consider acquired Fanconi syndrome when patients with nontyphoidal Salmonella bacteremia present with electrolyte disorders.

DOI： 10.2169/internalmedicine.5932-20

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Journal of Infection and Chemotherapy  

DOI： 10.1016/j.jiac.2018.08.017

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Journal of Infection and Chemotherapy  

DOI： 10.1016/j.jiac.2018.05.013

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1099/jmm.0.000601

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PubMed

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：ELSEVIER SCIENCE BV  

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1097/MD.0000000000007969

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PubMed

記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jiac.2016.11.008

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掲載種別：研究論文（学術雑誌）   出版者・発行元：日本臨床微生物学会  

掲載種別：研究論文（学術雑誌）   出版者・発行元：南江堂  

記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：American Journal of Infection Control  

DOI： 10.1016/j.ajic.2016.03.045

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Internal Medicine  

We herein report a 52-year-old man infected with human immunodeficiency virus (HIV) who was referred to our hospital due to the development of severe neurocognitive disorders and bilateral leukoencephalopathy. He has been treated with antiretroviral agents for 17 years, but low-level viremia has been detected consistently prior to admission. Drug resistant testing of the serum and the cerebrospinal fluid (CSF) both demonstrated a M184V mutation. A brain biopsy revealed perivascular CD8⁺ T-lymphocyte infiltration, leading to the diagnosis of CD8 encephalitis. The clinical symptoms improved drastically after changing to a nucleoside reverse transcriptase inhibitor sparing regimen, which subsequently decreased the HIV viral load to an undetectable level in both the serum and CSF.<br>

DOI： 10.2169/internalmedicine.55.5783

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Internal Medicine  

We herein report a case of laryngeal Kaposi's sarcoma (KS) complicated by immune reconstitution inflammatory syndrome in a human immunodeficiency virus (HIV)-infected patient. The patient initially presented with KS involving the larynx, which was successfully treated with pegylated liposomal doxorubicin (PLD) and antiretroviral therapy (ART). PLD was discontinued after 2 courses because of a marked clinical improvement; however, the patient experienced progressive odynophagia and dyspnea 2 months after the initiation of ART. Laryngoscopy revealed a severely swollen, inflamed epiglottis. The readministration of PLD was successful, and the patient was thereafter discharged without any subsequent complications.<br>

DOI： 10.2169/internalmedicine.55.5813

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Medicine (United States)  

DOI： 10.1097/MD.0000000000000861

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掲載種別：研究論文（学術雑誌）   出版者・発行元：日本渡航医学会  

掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本医療薬学会  

DOI： 10.20825/amjsphcs.25.0_362_2

掲載種別：研究論文（学術雑誌）   出版者・発行元：Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases  

背景：抗HIV 療法の進歩によってHIV 感染者の長期生存が可能になってきた現在，HIV 関連神経認知障害（HAND）が問題となりつつある．本邦においてHAND の報告は少なく，臨床像や有病率は明らかではない． 対象・方法：都立駒込病院において，平成18 年度のエイズ研究事業で作成された8 つの神経心理検査からなるHIV 感染者高次機能評価バッテリーが30 人のHIV 感染者に施行された．中枢神経合併症のため5 人が除外され，HAND の合併が疑われた25 人の患者背景，頭部MRI 所見，髄液所見，神経心理検査結果を重症度別に比較した．また，バッテリー内の一部の検査を組み合わせて，簡易バッテリーとして用いた場合の検討を行った． 結果：25 人中19 人（76％）がHAND と診断され，その内訳は7 人がHIV 認知症，8 人が軽度神経認知障害，4 人が無症候性神経認知障害であった．重症度別では，患者背景，頭部MRI 所見，髄液所見はいずれも一定の傾向が見られなかった．簡易バッテリーの検討では，International HIV Dementia Scale もしくは符号の検査のいずれかがカットオフ値以下であった場合，94.7％のHAND 症例は検出可能であった． 結論：臨床的にHAND の合併が疑われた大部分のHIV 感染者に対してHAND の診断がなされた．HIV 感染者高次機能評価バッテリー内の一部の神経心理検査は有用であったが，現行のHAND の診断基準に合致したものに改訂する必要がある．

DOI： 10.11150/kansenshogakuzasshi.88.141

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掲載種別：研究論文（学術雑誌）   出版者・発行元：Internal Medicine  

We herein report the case of 41-year-old homosexual man who presented to our hospital with typical acute retroviral syndrome. Complications of bilateral facial nerve palsy and appendicitis appeared eight days after admission. The bilateral facial nerve palsy spontaneously recovered one month later; however, the appendicitis required surgical intervention. To our knowledge, this is the first reported case of appendicitis related to acute retroviral syndrome.<br>

DOI： 10.2169/internalmedicine.53.0636

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掲載種別：研究論文（学術雑誌）   出版者・発行元：メディカルレビュー社  

掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本感染症学会  

We report on a previously healthy 56-year-old woman who was referred to our hospital with fever and progressive left foot pain. She had been bitten by a cat 7 days previously, and cephalosporins had been prescribed for treatment. However, her clinical symptoms deteriorated, and physical examination on admission was compatible with necrotizing fasciitis. Treatment with ampicillin-sulbactam and clindamycin was initiated. In addition, immediate surgical debridement was performed, resulting in therapeutic success. Culture of the necrotizing tissue grew multiple organisms, including <i>Pasteurella multocida</i> and <i>Bacteroides caccae</i>. Administration of appropriate antibiotics after a cat bite is essential for the prevention of potentially fatal complications.

DOI： 10.11150/kansenshogakuzasshi.87.211

PubMed

掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.resinv.2012.09.003

PubMed

掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本内科学会  

The case of a 66-year-old woman with untreated diabetes mellitus who was admitted to our hospital with a fever, hypotension and an altered mental status is herein reported. Computed tomography revealed bilateral emphysematous pyelonephritis along with a splenic abscess. Blood and urine cultures grew <i>Escherichia coli.</i> Treatment with systemic antibiotics combined with the insertion of percutaneous and renoureteral catheters was successful. The patient was discharged and completed treatment without developing any subsequent complications.<br>

DOI： 10.2169/internalmedicine.52.8302

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PubMed

掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本内科学会  

We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.<br>

DOI： 10.2169/internalmedicine.51.6830

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PubMed

掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.rmed.2011.03.009

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掲載種別：研究論文（学術雑誌）   出版者・発行元：南江堂  

掲載種別：研究論文（学術雑誌）  

掲載種別：研究論文（学術雑誌）  

PubMed

記述言語：日本語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society  

We describe a case of fulminant community-acquired Acinetobacter baumannii pneumonia. A 68-year-old woman, who had no past medical history, was admitted with septic shock and pneumonia of left lower lobe. Despite intensive treatment she died on day 3 after admission. To the best of our knowledge, this is the 4th report of community-acquired Acinetobacter pneumonia in Japan and the 1st report in a healthy patient. We report a case of Acinetobacter pneumonia and discuss the clinical characteristics of the community-acquired type compared with the hospital-acquired type.

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掲載種別：研究論文（学術雑誌）   出版者・発行元：一般社団法人 日本アレルギー学会  

DOI： 10.15036/arerugi.60.487_3

記述言語：日本語

記述言語：日本語

開催年月日： 2021年1月

記述言語：日本語   会議種別：口頭発表（招待・特別）  

開催地：web開催   国名：日本国  

COVID-19を含んだ歯科医が行うべき感染対策について講演をおこなった。

真菌感染症、輸入真菌症、高齢者医療と真菌症

渡航医学の概要、COVID-19での渡航医学の変化

真菌感染症、輸入感染症、高齢者医療と真菌症

近年話題となっているデング熱やジカ熱のような蚊媒介性感染症、出血熱、多剤耐性菌の保菌など海外渡航と関連する感染症について解説する。
蚊媒介性感染症，出血熱，Coronavirus，多剤耐性菌

真菌感染症、輸入感染症、高齢者医療と真菌症

近年話題となっているデング熱やジカ熱のような蚊媒介性感染症、出血熱、多剤耐性菌
の保菌など海外渡航と関連する感染症について解説する。

常識として知っておきたいHIV/AIDSの現在、と第してHIVについての疾患概要、偏見の歴史、現在の状況について講義を行った。