Updated on 2021/07/28

写真a

 
MORIOKA Hiroshi
 
Organization
Nagoya University Hospital Center of National University Hospital for Infection Control Assistant Professor
Graduate School
Graduate School of Medicine
Title
Assistant Professor

Degree 1

  1. 博士(医学) ( 2017.9   名古屋大学 ) 

Research Areas 1

  1. Life Science / Hygiene and public health (non-laboratory)

Research History 1

  1. Nagoya University   Nagoya University Hospital Center of National University Hospital for Infection Control   Assistant Professor

    2017.10

Professional Memberships 4

  1. THE JAPANESE SOCIETY FOR CLINICAL MICROBIOLOGY

  2. THE JAPANESE ASSOCIATION FOR INFECTIOUS DISEASES

  3. THE JAPANESE RESPIRATORY SOCIETY

  4. THE JAPANESE SOCIETY OF INTERNAL MEDICINE

Awards 1

  1. 日本感染症学会中日本地方会学術奨励賞

    2017.10   日本感染症学会   Point Prevalence Surveyによる4大学病院の病院疫学

    森岡 悠

 

Papers 32

  1. A Case Report of Bursitis, Bacteremia, and Disseminated Infection of Mycobacteroides (Mycobacterium) abscessus subsp. massiliense.

    Oka K, Morioka H, Eguchi M, Sato Y, Tetsuka N, Iguchi M, Kanematsu T, Fukano H, Hoshino Y, Kiyoi H, Yagi T

    Internal medicine (Tokyo, Japan)     2021.3

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    Publishing type:Research paper (scientific journal)   Publisher:一般社団法人 日本内科学会  

    <p>We herein report a 59-year-old woman with a 2-year history of chronic bursitis of the hand who took 50 mg/day prednisolone for several autoimmune diseases. <i>Mycobacteroides abscessus</i> subsp. <i>massiliense</i> was isolated from the abscess and blood culture. Combination therapy (imipenem/cilastatin, amikacin, and clarithromycin) was administered for a month. Two months later, <i>M. massiliense</i> was detected from a blood culture again, and disseminated lesions were found. Clarithromycin and sitafloxacin were administered following eight weeks of the same regimen. Six months after the diagnosis, <i>M. massiliense</i> was isolated from a blood culture, and she expired due to multiple organ failure. </p>

    DOI: 10.2169/internalmedicine.6189-20

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  2. Acquired Fanconi Syndrome in a Patient with Nontyphoidal Salmonella Bacteremia.

    Akihiro Ryuge, Shoji Saito, Hiroshi Morioka, Asaka Hachiya, Noritoshi Kato, Takuji Ishimoto, Tomoki Kosugi, Shoichi Maruyama

    Internal medicine (Tokyo, Japan)   Vol. 60 ( 5 ) page: 761 - 764   2021

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    Nontyphoidal Salmonella is a common cause of bacterial gastroenteritis, occasionally causing bacteremia. We herein report the case of an 80-year-old man who presented with bacteremia and pre-renal acute kidney injury (AKI) secondary to diarrhea caused by nontyphoidal Salmonella. Despite AKI improvement on fluid administration, some serological abnormalities, such as hypokalemia, hypophosphatemia, and hypouricemia, and abnormal urinary findings emerged, including renal glycosuria and aminoaciduria. Fractional excretion of phosphate and uric acid was increased, suggesting that the serological and urinary abnormalities may have arisen from Fanconi syndrome. Physicians should consider acquired Fanconi syndrome when patients with nontyphoidal Salmonella bacteremia present with electrolyte disorders.

    DOI: 10.2169/internalmedicine.5932-20

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  3. Fungal endocarditis after transcatheter aortic valve replacement (TAVR): Case report and review of literature. International journal

    Hiroshi Morioka, Yoshiyuki Tokuda, Hideki Oshima, Mitsutaka Iguchi, Yuka Tomita, Akihiko Usui, Tetsuya Yagi

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   Vol. 25 ( 3 ) page: 215 - 217   2019.3

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    The reported number of transcatheter aortic valve replacement-associated infective endocarditis (TAVR-IE) cases has been increasing worldwide, but information about the incidence and clinical features of fungal TAVR-IE is quite limited. We present a patient who acquired TAVR-IE caused by Candida parapsilosis four month after TAVR, who was successfully treated redo-aortic valve replacement and prolonged antifungal therapy.

    DOI: 10.1016/j.jiac.2018.08.017

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  4. Active surveillance in response to the identification of a single carbapenemase-producing Escherichia coli at a Japanese university hospital. International journal

    Daizo Kato, Hiroshi Morioka, Yuka Tomita, Mitsutaka Iguchi, Aki Hirabayashi, Noriyuki Tetsuka, Takuya Sadomoto, Miyuki Hyodo, Mariko Mochizuki, Yukari Osada, Masato Yamamoto, Yoshiaki Kato, Takayuki Inagaki, Kazuya Ichikawa, Tetsuya Yagi

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy   Vol. 24 ( 12 ) page: 1013 - 1015   2018.12

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    Publishing type:Research paper (scientific journal)   Publisher:Elsevier B.V.  

    This report described the experience of active surveillance culture implemented in response to the identification of a single carbapenemase-producing Escherichia coli in a Japanese university hospital. It revealed a horizontal transmission event and an additional asymptomatic carrier of carbapenemase-producing Escherichia coli with unique drug susceptibility and resistance gene profiles. Early implementation of active surveillance culture as a part of multifaceted infection control measures appeared to be useful to control further transmission of carbapenemase-producing Escherichia coli even in the low endemic facility. Further investigations on the timing and usefulness of active surveillance culture in the control of carbapenemase-producing Enterobacteriaceae would be warranted.

    DOI: 10.1016/j.jiac.2018.05.013

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  5. The first multi-centre point-prevalence survey in four Japanese university hospitals

    Morioka H., Nagao M., Yoshihara S., Ohge H., Kasahara K., Shigemoto N., Kajihara T., Mori M., Iguchi M., Tomita Y., Ichiyama S., Yagi T.

    JOURNAL OF HOSPITAL INFECTION   Vol. 99 ( 3 ) page: 325-331   2018.7

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    DOI: 10.1016/j.jhin.2018.03.005

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  6. Risk factors for and role of OprD protein in increasing minimal inhibitory concentrations of carbapenems in clinical isolates of Pseudomonas aeruginosa

    Hirabayashi Aki, Kato Daizo, Tomita Yuka, Iguchi Mitsutaka, Yamada Keiko, Kouyama Yuichi, Morioka Hiroshi, Tetsuka Nobuyuki, Yagi Tetsuya

    JOURNAL OF MEDICAL MICROBIOLOGY   Vol. 66 ( 11 ) page: 1562 - 1572   2017.11

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    DOI: 10.1099/jmm.0.000601

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  7. Appropriateness of surgical prophylaxis contributed to significant reduction of oral cephalosporins in a Japanese university hospital

    Morioka Hiroshi, Kato Yoshiaki, Inagaki Takayuki, Tetsuka Nobuyuki, Iguchi Mitsutaka, Tomita Yuka, Yagi Tetsuya

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS   Vol. 50   page: S42-S43   2017.11

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  8. Appropriateness of surgical prophylaxis contributed to significant reduction of oral cephalosporins in a Japanese university hospital

    Hiroshi Morioka, Yoshiaki Kato, Takayuki Inagaki, Nobuyuki Tetsuka, Mitsutaka Iguchi, Yuka Tomita, Tetsuya Yagi

    INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS   Vol. 50   page: S42 - S43   2017.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE BV  

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  9. Recurrent bacteremia and liver abscess caused by Clostridium difficile A case report

    Morioka Hiroshi, Iguchi Mitsutaka, Kuzuya Teiji, Mikamo Hiroshige, Yagi Tetsuya

    MEDICINE   Vol. 96 ( 35 ) page: e7969   2017.9

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    DOI: 10.1097/MD.0000000000007969

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  10. Pneumococcal biliary tract infections - How rare are they?

    Morioka Hiroshi, Iguchi Mitsutaka, Oodate Mitsuru, Yoneda Masaki, Ushijima Futoshi, Hirabayashi Aid, Tetsuka Nobuyuki, Tomita Yuka, Kato Daizo, Yagi Tetsuya

    JOURNAL OF INFECTION AND CHEMOTHERAPY   Vol. 23 ( 6 ) page: 415 - 418   2017.6

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    DOI: 10.1016/j.jiac.2016.11.008

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  11. A case of sepsis caused by intra abdominal infection with Mycoplasma hominis after Caesarean section

      Vol. 27 ( 1 ) page: 23 - 28   2017

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  12. デバイス関連感染症の予防 (特集 感染症対策update : ひろげない,ふやさない,もらわない) -- (病原体をひろげないための方策)

    森岡 悠, 井口 光孝

    内科   Vol. 118 ( 5 ) page: 885 - 889   2016.11

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    Publishing type:Research paper (scientific journal)   Publisher:南江堂  

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  13. The first point prevalence survey of health care-associated infection and antimicrobial use in a Japanese university hospital: A pilot study. International journal

    Hiroshi Morioka, Aki Hirabayashi, Mitsutaka Iguchi, Yuka Tomita, Daizo Kato, Naokazu Sato, Miyuki Hyodo, Naoko Kawamura, Takuya Sadomoto, Kazuya Ichikawa, Takayuki Inagaki, Yoshiaki Kato, Yuichi Kouyama, Yoshinori Ito, Tetsuya Yagi

    American journal of infection control   Vol. 44 ( 7 ) page: E119 - E123   2016.7

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:MOSBY-ELSEVIER  

    BACKGROUND: Point prevalence surveys (PPSs) in Japanese hospitals have not yet been reported. The purpose of this pilot PPS study was to evaluate the epidemiology of health care-associated infections (HAIs) and antimicrobial use in a Japanese tertiary university hospital. METHODS: A 1-day, cross-sectional PPS was performed at a Japanese university hospital. Data on demographics, active HAIs, and antimicrobial use of all inpatients were collected using a data collection form. RESULTS: Of 841 patients, 85 (10.1%) had 90 active HAIs, and 308 patients (36.6%) were administered 494 antimicrobials. Among the 90 HAIs and 58 pathogens, the most frequent infection and isolated pathogen were pneumonia (20.0%) and Enterobacteriaceae (27.6%), respectively. Of the 118 antimicrobials used for treatment of HAIs, carbapenems were the most frequently administered category of antimicrobials (22.9%). In regard to antimicrobials for surgical prophylaxis, 37 of 119 (31.1%) were administered to patients on postoperative day 3 or later, and 48 of 119 (40.3%) were administered orally. CONCLUSIONS: The incidence of HAIs is higher than in other developed countries. The social and medical situation in Japan may affect patient demographics, active HAIs, and antimicrobial use. Multicenter PPSs are necessary to uncover the real epidemiology of HAIs and antimicrobial use in Japan.

    DOI: 10.1016/j.ajic.2016.03.045

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  14. The first point prevalence survey of health care–associated infection and antimicrobial use in a Japanese university hospital: A pilot study

    Morioka Hiroshi, Hirabayashi Aki, Iguchi Mitsutaka, Tomita Yuka, Kato Daizo, Sato Naokazu, Hyodo Miyuki, Kawamura Naoko, Sadomoto Takuya, Ichikawa Kazuya, Inagaki Takayuki, Kato Yoshiaki, Kouyama Yuichi, Ito Yoshinori, Yagi Tetsuya

    American Journal of Infection Control   Vol. 44 ( 7 ) page: e119 - e123   2016.7

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    Background: Point prevalence surveys (PPSs) in Japanese hospitals have not yet been reported. The purpose of this pilot PPS study was to evaluate the epidemiology of health care–associated infections (HAIs) and antimicrobial use in a Japanese tertiary university hospital. Methods: A 1-day, cross-sectional PPS was performed at a Japanese university hospital. Data on demographics, active HAIs, and antimicrobial use of all inpatients were collected using a data collection form. Results: Of 841 patients, 85 (10.1%) had 90 active HAIs, and 308 patients (36.6%) were administered 494 antimicrobials. Among the 90 HAIs and 58 pathogens, the most frequent infection and isolated pathogen were pneumonia (20.0%) and Enterobacteriaceae (27.6%), respectively. Of the 118 antimicrobials used for treatment of HAIs, carbapenems were the most frequently administered category of antimicrobials (22.9%). In regard to antimicrobials for surgical prophylaxis, 37 of 119 (31.1%) were administered to patients on postoperative day 3 or later, and 48 of 119 (40.3%) were administered orally. Conclusions: The incidence of HAIs is higher than in other developed countries. The social and medical situation in Japan may affect patient demographics, active HAIs, and antimicrobial use. Multicenter PPSs are necessary to uncover the real epidemiology of HAIs and antimicrobial use in Japan.

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  15. CD8 Encephalitis Caused by Persistently Detectable Drug-resistant HIV.

    Hiroshi Morioka, Naoki Yanagisawa, Shugo Sasaki, Noritaka Sekiya, Akihiko Suganuma, Akifumi Imamura, Atsushi Ajisawa, Shuji Kishida

    Internal medicine (Tokyo, Japan)   Vol. 55 ( 10 ) page: 1383 - 1386   2016

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    We herein report a 52-year-old man infected with human immunodeficiency virus (HIV) who was referred to our hospital due to the development of severe neurocognitive disorders and bilateral leukoencephalopathy. He has been treated with antiretroviral agents for 17 years, but low-level viremia has been detected consistently prior to admission. Drug resistant testing of the serum and the cerebrospinal fluid (CSF) both demonstrated a M184V mutation. A brain biopsy revealed perivascular CD8(+) T-lymphocyte infiltration, leading to the diagnosis of CD8 encephalitis. The clinical symptoms improved drastically after changing to a nucleoside reverse transcriptase inhibitor sparing regimen, which subsequently decreased the HIV viral load to an undetectable level in both the serum and CSF.

    DOI: 10.2169/internalmedicine.55.5783

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  16. Laryngeal Kaposi's Sarcoma Complicated by the Immune Reconstitution Inflammatory Syndrome in an HIV-infected Patient.

    Hirofumi Kato, Naoki Yanagisawa, Hiroshi Morioka, Shugo Sasaki, Noritaka Sekiya, Akihiko Suganuma, Akifumi Imamura, Atsushi Ajisawa

    Internal medicine (Tokyo, Japan)   Vol. 55 ( 8 ) page: 1001 - 1005   2016

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    We herein report a case of laryngeal Kaposi's sarcoma (KS) complicated by immune reconstitution inflammatory syndrome in a human immunodeficiency virus (HIV)-infected patient. The patient initially presented with KS involving the larynx, which was successfully treated with pegylated liposomal doxorubicin (PLD) and antiretroviral therapy (ART). PLD was discontinued after 2 courses because of a marked clinical improvement; however, the patient experienced progressive odynophagia and dyspnea 2 months after the initiation of ART. Laryngoscopy revealed a severely swollen, inflamed epiglottis. The readministration of PLD was successful, and the patient was thereafter discharged without any subsequent complications.

    DOI: 10.2169/internalmedicine.55.5813

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  17. Disseminated Mycobacterium abscessus Infection Following Septic Arthritis: A Case Report and Review of the Literature. International journal

    Shoichi Fukui, Noritaka Sekiya, Yasunobu Takizawa, Hiroshi Morioka, Hirofumi Kato, Akio Aono, Kinuyo Chikamatsu, Satoshi Mitarai, Satomi Kobayashi, Satoshi Kamei, Keigo Setoguchi

    Medicine   Vol. 94 ( 21 ) page: e861   2015.5

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    Mycobacterium abscessus is a rapidly growing mycobacterium found mainly in patients with respiratory or cutaneous infections, but it rarely causes disseminated infections. Little is known about the clinical characteristics, treatment, and prognosis of disseminated M abscessus infection. A 75-year-old Japanese woman who had been treated for 17 years with a corticosteroid for antisynthetase syndrome with antithreonyl-tRNA synthetase antibody developed swelling of her right elbow. X-ray of her right elbow joint showed osteolysis, and magnetic resonance imaging revealed fluid in her right elbow joint. M abscessus grew in joint fluid and blood cultures. She was diagnosed with a disseminated M abscessus infection following septic arthritis. Antimicrobial treatment by clarithromycin, amikacin, and imipenem/cilastatin combined with surgical debridement was administered. Although blood and joint fluid cultures became negative 1 week later, the patient died at 6 weeks from starting antimicrobial treatment. We reviewed 34 cases of disseminated M abscessus infections from the literature. Most of the patients had immunosuppressive backgrounds such as transplantation, use of immunosuppressive agents, hematological malignancy, and end stage renal disease. The duration from onset of symptoms to diagnosis was over 3 months in half of the cases. All fatal cases had positive blood cultures or use of immunosuppressive agents. Clinicians should bear in mind that mycobacterial infections including M abscessus are one of the differential diagnoses in patients with subacute arthritis and soft tissue infections.

    DOI: 10.1097/MD.0000000000000861

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  18. A型肝炎ワクチン(エイムゲンとHavrix)接種後の抗体価と互換性に関する検討

    菊池 均, 宮津 光伸, 永田 俊人, 後藤 泰浩, 山本 悦子, 森岡 悠, 佐藤 好隆

    日本渡航医学会誌 = Journal of the Japanese Society of Travel and Health   Vol. 9 ( 1 ) page: 48 - 50   2015

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  19. P0578-22-AM 注射用抗菌薬届出システムの構築と適正使用に向けた介入方法の検討(感染制御(その他)1,ポスター発表,一般演題,医療薬学の進歩と未来-次の四半世紀に向けて-)

    加藤 善章, 八木 哲也, 山田 清文, 山本 雅人, 稲垣 孝行, 手塚 宜行, 森岡 悠, 平林 亜希, 井口 光孝, 加藤 大三, 冨田 ゆうか

    日本医療薬学会年会講演要旨集   Vol. 25 ( 0 )   2015

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    Publishing type:Research paper (scientific journal)   Publisher:一般社団法人 日本医療薬学会  

    DOI: 10.20825/amjsphcs.25.0_362_2

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  20. Evaluation of HIV-infected Patients Suspected as Having HIV-associated Neurocognitive Disorders

    MORIOKA Hiroshi, KISHIDA Shuji, IMAMURA Akifumi, SEKIYA Noritaka, YANAGISAWA Naoki, SUGANUMA Akihiko, AJISAWA Atsushi

    Kansenshogaku Zasshi   Vol. 88 ( 2 ) page: 141 - 8   2014.3

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    Publishing type:Research paper (scientific journal)   Publisher:The Japanese Association for Infectious Diseases  

    Background:HIV-associated neurocognitive disorders (HAND) have emerged as a problem among HIV-infected individuals in the era of antiretroviral therapy. However, there are insufficient data on HAND regarding its prevalence and clinical features in Japan. Methods:A test battery composed of eight neuropsycological tests proposed by the Ministry of Health,Labour and Welfare (MHLW test battery) was applied to assess 30 subjects at Tokyo Metropolitan Komagome Hospital. Among them, 5 subjects were excluded due to central nervous system complications. The background of each patient along with the results of head magnetic resonance imaging (MRI), cerebrospinal fluid (CSF) analysis and neuropsychological tests were compared to each HAND category. In addition, the clinical utility of a combination of neuropsychological tests as an abbreviated test battery of HAND was evaluated. Results:A total of 19 (76%) subjects were diagnosed as having a HAND. Among them, HIV-associated dementia, mild neurocognitive disorders and asymptomatic neurocognitive disorders were diagnosed in 7, 8,and 4 subjects, respectively. Neither the patientʼs background nor the results of the head MRI and CSF analysis showed relevance to disease severity. The conventional International HIV Dementia Scale with the Digit Symbol Substitute Test was capable of detecting 94.7%cases of HAND. Conclusions:Most HIV-infected subjects clinically suspected as having neurocognitive disorders were diagnosed as having a HAND. Neuropsychological tests of the MHLW test battery were in some part useful to diagnose HAND. However, more precise neuropsychological tests are warranted to screen and diagnose HAND, based on the current criteria.

    DOI: 10.11150/kansenshogakuzasshi.88.141

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  21. [A case of spinal tuberculosis in a young Filipino man].

    Hiroshi Morioka, Naoki Yanagisawa, Noritaka Sekiya, Akihiko Suganuma, Akifumi Imamura, Atsushi Ajisawa

    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases   Vol. 88 ( 1 ) page: 126 - 30   2014.1

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    A 19-year-old Filipino man was admitted to our hospital because of persisting fever and back pain. He had recognized his symptoms 6 months previously, but a definite diagnosis was not made. Image testing demonstrated a compressed fracture of the thoracic vertebrae accompanied with a perivertebral abscess. A biopsy specimen revealed granuloma compatible with tuberculosis (TB). Anti-TB drugs were initiated, and his clinical symptoms steadily improved. However, he developed neuropathic symptoms due to exacerbation of the abscess two months after starting the anti-TB drugs. An immediate laminectomy was performed resulting in symptom relief; however severe kyphosis remained. Polymerase chain reaction testing of the abscess collected during the operation was positive for Mycobacterium tuberculosis, confirming the diagnosis of spinal TB. The diagnosis of spinal TB has been a challenge world-wide. Clinicians should be aware of the demographic background as well as the clinical and laboratory features of spinal tuberculosis, facilitating earlier diagnosis.

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  22. Bilateral Facial Nerve Palsy and Appendicitis Occurring during Acute Retroviral Syndrome

    Morioka Hiroshi, Sakamoto Naoya, Iwabuchi Sentaro, Ohnishi Kenji

    INTERNAL MEDICINE   Vol. 53 ( 2 ) page: 155 - 158   2014

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    We herein report the case of 41-year-old homosexual man who presented to our hospital with typical acute retroviral syndrome. Complications of bilateral facial nerve palsy and appendicitis appeared eight days after admission. The bilateral facial nerve palsy spontaneously recovered one month later; however, the appendicitis required surgical intervention. To our knowledge, this is the first reported case of appendicitis related to acute retroviral syndrome.<br>

    DOI: 10.2169/internalmedicine.53.0636

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  23. 神経心理検査で改善が示唆されたHIV-associated dementiaの1例

    森岡 悠, 今村 顕史

    HIV感染症とAIDSの治療   Vol. 5 ( 1 ) page: 46 - 48   2014

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  24. Necrotizing Fasciitis after a Cat Bite : A Case Report

    HOSODA Tomohiro, YANAGISAWA Naoki, MORIOKA Hiroshi, SUGANUMA Akihiko, IMAMURA Akifumi, AJISAWA Atsushi

    Kansenshogaku Zasshi   Vol. 87 ( 2 ) page: 211 - 4   2013.3

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    Publishing type:Research paper (scientific journal)   Publisher:The Japanese Association for Infectious Diseases  

    We report on a previously healthy 56-year-old woman who was referred to our hospital with fever and progressive left foot pain. She had been bitten by a cat 7 days previously, and cephalosporins had been prescribed for treatment. However, her clinical symptoms deteriorated, and physical examination on admission was compatible with necrotizing fasciitis. Treatment with ampicillin-sulbactam and clindamycin was initiated. In addition, immediate surgical debridement was performed, resulting in therapeutic success. Culture of the necrotizing tissue grew multiple organisms, including <i>Pasteurella multocida</i> and <i>Bacteroides caccae</i>. Administration of appropriate antibiotics after a cat bite is essential for the prevention of potentially fatal complications.

    DOI: 10.11150/kansenshogakuzasshi.87.211

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  25. Re-expansion pulmonary edema: evaluation of risk factors in 173 episodes of spontaneous pneumothorax. International journal

    Hiroshi Morioka, Kazuto Takada, Shuuichi Matsumoto, Eiji Kojima, Susumu Iwata, Shoutaro Okachi

    Respiratory investigation   Vol. 51 ( 1 ) page: 35 - 9   2013.3

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    BACKGROUND: The precise incidence and clinical features of re-expansion pulmonary edema (RPE) are unclear, and they vary among reports. In this study, we assessed the incidence, risk factors, and outcomes of patients with RPE over a 3-yr period in a general hospital, with the goal of proposing a primary intervention for pneumothorax. METHODS: We retrospectively reviewed records of inpatients with spontaneous pneumothorax treated by tube thoracostomy between October 2007 and December 2010. RESULTS: A total of 173 episodes of spontaneous pneumothorax occurred in 156 patients. The incidence of RPE was 27/173 (15.6%). Symptom duration and pneumothorax size were significant risk factors for RPE, and the occurrence of RPE was independent of primary treatment of spontaneous pneumothorax. Among the patients with RPE, 18 (67%) were symptomatic. Five patients (18.5%) were treated with temporary oxygen, however, 21 patients (78%) did not need any treatment. All patients survived and none required mechanical ventilation. The occurrence of RPE did not influence the clinical outcome. CONCLUSIONS: The risk of developing RPE increases with an increased duration or size of pneumothorax. Our results suggest that the methods of primary intervention, including prompt suction, do not affect the onset of RPE. Close observation is always required regardless of the intervention because of the potentially fatal complications.

    DOI: 10.1016/j.resinv.2012.09.003

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  26. Bilateral Emphysematous Pyelonephritis with a Splenic Abscess

    Morioka Hiroshi, Yanagisawa Naoki, Suganuma Akihiko, Imamura Akifumi, Ajisawa Atsushi

    INTERNAL MEDICINE   Vol. 52 ( 1 ) page: 147 - 150   2013

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    Publishing type:Research paper (scientific journal)   Publisher:一般社団法人 日本内科学会  

    The case of a 66-year-old woman with untreated diabetes mellitus who was admitted to our hospital with a fever, hypotension and an altered mental status is herein reported. Computed tomography revealed bilateral emphysematous pyelonephritis along with a splenic abscess. Blood and urine cultures grew <i>Escherichia coli.</i> Treatment with systemic antibiotics combined with the insertion of percutaneous and renoureteral catheters was successful. The patient was discharged and completed treatment without developing any subsequent complications.<br>

    DOI: 10.2169/internalmedicine.52.8302

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  27. Paradoxical Infarct in Tuberculous Meningitis: A Case Report

    Morioka Hiroshi, Matsumoto Shuuichi, Kojima Eiji, Takada Kazuto, Iwata Susumu, Okachi Shoutaro

    INTERNAL MEDICINE   Vol. 51 ( 8 ) page: 949 - 951   2012

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    We describe a case of 78-year-old woman with a 1-week history of fever and left hemiparesis. Head magnetic resonance imaging showed a small infarct. After admission, she showed altered consciousness and another small infarct. She finally had diagnoses of miliary tuberculosis (miliary-TB) and tuberculous meningitis (TBM). She recovered after receiving anti-tuberculous therapy (ATT) with prednisolone. However, 5 weeks later, we found another infarct. This is a rare case of TBM with recurrent infarcts in atypical lesions in spite of ATT. We suggest the possibility that the new infarct after ATT was due to a paradoxical reaction.<br>

    DOI: 10.2169/internalmedicine.51.6830

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  28. Prospective evaluation of the relationship between acute exacerbations of COPD and gastroesophageal reflux disease diagnosed by questionnaire. International journal

    Kazuto Takada, Shuuichi Matsumoto, Eiji Kojima, Susumu Iwata, Shoutarou Okachi, Kiyoko Ninomiya, Hiroshi Morioka, Kentarou Tanaka, Yasunori Enomoto

    Respiratory medicine   Vol. 105 ( 10 ) page: 1531 - 1536   2011.10

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    Publishing type:Research paper (scientific journal)  

    BACKGROUND: Little is known about the relationship between acute exacerbations of COPD (AECOPD) and gastroesophageal reflux disease (GERD). The aim of this study was to investigate the effects on AECOPD of GERD diagnosed by a questionnaire. METHODS: The subjects were 221 consecutive patients with stable COPD who were evaluated using the Frequency Scale for Symptoms of GERD (FSSG) and a prospective survey of AECOPD for one year. Patients taking drugs for acid suppression were excluded. The association between the frequency of AECOPD and the presence of GERD or FSSG score was examined. RESULTS: Based on the FSSG, the prevalence of GERD was 26.7%. AECOPD and hospitalization due to AECOPD were significantly more frequent in patients with GERD than in those without GERD, with crude relative risks of 3.42 and 3.66, respectively. Multivariate analyses showed that GERD and COPD stage IV were significant predictors of hospitalization due to AECOPD, independent of respiratory therapies or patient characteristics. The severity of GERD symptoms, as measured by the FSSG score, was significantly correlated with the frequencies of AECOPD and hospitalization due to AECOPD. Similar correlations were seen for the FSSG subscores for acid reflux and gastric dysmotility. CONCLUSIONS: This prospective cohort study showed that GERD appears to be a predictive factor for hospitalization due to AECOPD and that severer GERD symptoms may be associated with more frequent AECOPD. Thus, further studies are warranted to evaluate the preventive effect of the therapy for GERD on AECOPD.

    DOI: 10.1016/j.rmed.2011.03.009

    Web of Science

    PubMed

  29. Case report: A case of pneumocystis pneumonia after etanercept therapy

      Vol. 108 ( 3 ) page: 555 - 557   2011.9

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    CiNii Article

  30. A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman

    MORIOKA Hiroshi, MATSUMOTO Shuuichi, KOJIMA Eiji, TAKADA Kazuto, SHIZU Masato, OKACHI Shoutarou

      Vol. 49 ( 1 ) page: 57 - 61   2011.1

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  31. [A case of fulminant community-acquired Acinetobacter pneumonia in a healthy woman].

    Morioka H, Matsumoto S, Kojima E, Takada K, Shizu M, Okachi S

    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society   Vol. 49 ( 1 ) page: 57 - 61   2011.1

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    PubMed

  32. P2-09-3 FeNO高値の気管支喘息患者に対するブデゾニド/ホルモテロール配合薬による薬物療法の効果と安全性(P2-09 成人喘息5,ポスターセッション,第23回日本アレルギー学会春季臨床大会)

    岩田 晋, 後藤 大揮, 清水 隆宏, 松本 修一, 小島 英嗣, 高田 和外, 岡地 祥太郎, 二宮 記代子, 森岡 悠, 田中 健太郎, 榎本 泰典

    アレルギー   Vol. 60 ( 3 )   2011

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    Publishing type:Research paper (scientific journal)   Publisher:一般社団法人 日本アレルギー学会  

    DOI: 10.15036/arerugi.60.487_3

    CiNii Article

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Books 3

  1. こういうときはこうする! 感染症クリスタルエビデンス 感染対策・予防編

    岡 秀昭, 加藤 英明( Role: Contributor ,  手術時は滅菌手袋を二重に着用するべきか?)

    金芳堂  2020.2  ( ISBN:4765318133

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    Total pages:309   Language:Japanese

    CiNii Books

    ASIN

  2. すべての医療機関で役立つ 抗菌薬耐性対策サーベイランス必読ガイド

    森岡 悠( Role: Joint author)

    じほう  2016.8 

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    Language:Japanese

  3. 長期療養時代のHIV感染症/AIDSマニュアル

    森岡 悠( Role: Joint author)

    2014.8 

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    Language:Japanese

MISC 1

  1. Antimicrobial stewardship in dental practice Invited

    Hiroshi Morioka

    THE JOURNAL OF BIOMEDICAL SCIENCE AND BIOSAFETY   Vol. 33 ( 3 ) page: 41 - 47   2021.7

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

KAKENHI (Grants-in-Aid for Scientific Research) 1

  1. 地域の大規模疫学データが抗菌薬適正使用に与える影響の評価

    Grant number:20K18880  2020.4 - 2024.3

    若手研究

    森岡 悠

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    Authorship:Principal investigator 

    Grant amount:\2470000 ( Direct Cost: \1900000 、 Indirect Cost:\570000 )

    2020年に愛知県の多施設の病院で行った横断的疫学研究の結果を、愛知県の各施設にフィードバックを行う。
    2022年-2023年の段階で①2020-2022年にかけての抗菌薬処方量の経年的変化、②周術期抗菌薬の適正性の評価を行う。①②とも、適正化が行われている/行われていない施設の要因解析を行い、地域での抗菌薬使用の適正化を進める際の有効な方法を探索する。