Updated on 2022/04/04

写真a

 
SUZUKI Toshihiko
 
Organization
Nagoya University Hospital Maternity and Perinatal Care Center Assistant Professor
Title
Assistant Professor

Degree 1

  1. Ph.D. (Medicine) ( 2020.7   Nagoya University ) 

Research Areas 1

  1. Life Science / Embryonic medicine and pediatrics

Current Research Project and SDGs 1

  1. The relationship between the carbon dioxide ventilatory response (CO2 response) and apnea

Professional Memberships 3

  1. 日本周産期・新生児医学会

  2. 日本新生児成育医学会

  3. 日本小児科学会

 

Papers 6

  1. Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy

    Suzuki Toshihiko, Sato Yoshiaki, Kushida Yoshihiro, Tsuji Masahiro, Wakao Shohei, Ueda Kazuto, Imai Kenji, Iitani Yukako, Shimizu Shinobu, Hida Hideki, Temma Takashi, Saito Shigeyoshi, Iida Hidehiro, Mizuno Masaaki, Takahashi Yoshiyuki, Dezawa Mari, Borlongan Cesar V, Hayakawa Masahiro

    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM   Vol. 41 ( 7 ) page: 1707 - 1720   2021.7

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/0271678X20972656

    Web of Science

    PubMed

  2. Mesenchymal stem/stromal cells stably transduced with an inhibitor of CC chemokine ligand 2 ameliorate bronchopulmonary dysplasia and pulmonary hypertension. Reviewed

    Suzuki T, Sato Y, Yamamoto H, Kato T, Kitase Y, Ueda K, Mimatsu H, Sugiyama Y, Onoda A, Saito S, Takahashi Y, Nakayama T, Hayakawa M

    Cytotherapy     2020.3

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    Authorship:Lead author   Language:English   Publishing type:Doctoral thesis  

    DOI: 10.1016/j.jcyt.2020.01.009

    PubMed

  3. A Novel Treatment with Stem Cells from Human Exfoliated Deciduous Teeth for Hypoxic-Ischemic Encephalopathy in Neonatal Rats

    Kitase Yuma, Sato Yoshiaki, Ueda Kazuto, Suzuki Toshihiko, Mikrogeorgiou Alkisti, Sugiyama Yuichiro, Matsubara Kohki, Okabe Yuka Tsukagoshi, Shimizu Shinobu, Hirata Hitoshi, Yukawa Hiroshi, Baba Yoshinobu, Tsuji Masahiro, Takahashi Yoshiyuki, Yamamoto Akihito, Hayakawa Masahiro

    STEM CELLS AND DEVELOPMENT   Vol. 29 ( 2 ) page: 63 - 74   2020.1

  4. Administration of Bone Marrow-Derived Mononuclear Cells Contributed to the Reduction of Hypoxic-lschemic Brain Injury in Neonatal Rats

    Sato Yoshiaki, Ueda Kazuto, Kondo Taiki, Hattori Tetsuo, Mikrogeorgiou Alkisti, Sugiyama Yuichiro, Suzuki Toshihiko, Yamamoto Michiro, Hirata Hitoshi, Hirakawa Akihiro, Nakanishi Keiko, Tsuji Masahiro, Hayakawa Masahiro

    FRONTIERS IN NEUROLOGY   Vol. 9   page: 987   2018.11

  5. Intravenous Administration of Bone Marrow-Derived Mesenchymal Stem Cell, but not Adipose Tissue-Derived Stem Cell, Ameliorated the Neonatal Hypoxic-Ischemic Brain Injury by Changing Cerebral Inflammatory State in Rat

    Sugiyama Yuichiro, Sato Yoshiaki, Kitase Yuma, Suzuki Toshihiko, Kondo Taiki, Mikrogeorgiou Alkisti, Horinouchi Asuka, Maruyama Shoichi, Shimoyama Yoshie, Tsuji Masahiro, Suzuki Satoshi, Yamamoto Tokunori, Hayakawa Masahiro

    FRONTIERS IN NEUROLOGY   Vol. 9   page: 757   2018.9

  6. 脳室周囲白質軟化症の重症度と拡散テンソル画像によるFA値との関係 Reviewed

    鈴木俊彦,城所博之, 久保田哲夫, 夏目淳, 根来民子

    脳と発達   Vol. 45 ( 1 ) page: 21-25   2013.1

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

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Presentations 5

  1. Intravenously transplanted Multilineage-differentiating stress enduring cells as a novel source for cell therapy to target neonatal hypoxic ischemic encephalopathy Invited International conference

    The 4th Taiwan-Korea-Japan Joint Congress on Neonatology  2022.3.19 

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    Event date: 2022.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Taiwan, Province of China  

  2. A novel treatment for perinatal hypoxic ischemic encephalopathy using Multilineage-differentiating stress enduring cells. Invited International conference

    Toshihiko Suzuki, Yoshiaki Sato,et al.

    Pediatric Academic Societies Meeting 2018 

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    Event date: 2018.5

    Language:English   Presentation type:Poster presentation  

    Country:Canada  

  3. 新生児慢性肺疾患に伴う肺高血圧症に対するMultilineage-differentiating stress enduring cellsを用いた治療効果の検討

    佐藤義朗、上田一仁、田中雅人、田中亮 三浦良介、呉尚治、浅田英之、北瀬悠磨、立花貴史、見松はるか、伊藤美春、齊藤明子、村松友佳子、早川昌弘

    成育医学会学術集会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:埼玉   Country:Japan  

  4. Multilineage-differentiating stress enduring cellsを用いた 新生児低酸素性虚血性脳症に対する 治療効果の検討

    佐藤義朗、呉尚治、上田一仁、 見松はるか、北瀬悠磨、杉山裕一朗1、近藤大貴、中西圭子、辻雅弘、早川昌弘

    成育医学会学術集会 

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    Event date: 2017.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:埼玉   Country:Japan  

  5. Mesenchymal stem cells stably transduced with a dominant-negative inhibitor of CCL2 ameliorate chronic lung disease and pulmonary hypertension. International conference

    Yoshiaki Sato , Taichi Kato, Kazuto Ueda, Mimatsu Haruka, Yuma Kitase, Alkisti Mikrogeorgiou, Yuichiro Sugiyama, Shigeki Saito, Takayuki Nakamura, Masahiro Hayakawa

    International Society for Stem Cell Research annual meeting 2017. 

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    Event date: 2017.6

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Boston, USA   Country:United States  

KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. 妊娠高血圧症候群に起因するSGAの慢性肺疾患の重症化機序解明と新規治療法開発

    Grant number: 19K08341  2019.4 - 2022.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Coinvestigator(s) 

    Grant amount:\4290000

  2. Muse細胞を用いた周産期脳障害の新規治療開発

    Grant number:26860844  2014.4 - 2017.3

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

    Grant amount:\3770000

Industrial property rights 1

  1. 多能性幹細胞による周産期脳障害の改善及び治療

    佐藤義朗、鈴木俊彦、清水忍、水野正明、早川昌弘、出澤真理

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    Applicant:佐藤義朗、鈴木俊彦、清水忍、水野正明、早川昌弘、出澤真理

    Application no:2016-098186  Date applied:2016.5

    Country of applicant:Domestic  

    Multilineage-differentiating Stress Enduring(Muse)細胞は、多能性を有し直接的に分化転換・組織修復を行うことができる間葉系幹細胞の数%を構成する細胞である。我々はHIEモデル動物で、Muse細胞が脳へ生着すること、並びに行動学的に学習及び運動障害の改善効果があることを確認した。現在HIEの治療法は、効果が限定的な低体温療法しかなく、新規治療法の開発が喫緊の課題とされている。本研究でMuse細胞を用いたHIEの新規治療法の開発を行うことにより、神経学的予後を改善する効果が期待できる。