Updated on 2024/03/11

写真a

 
USHIDA Takafumi
 
Organization
Nagoya University Hospital Obstetrics and Gynecology Lecturer
Graduate School
Graduate School of Medicine
Title
Lecturer

Degree 1

  1. 医学博士 ( 2017.7   名古屋大学 ) 

Research Interests 4

  1. エピジェネティクス

  2. メタボリック症候群

  3. 心血管障害

  4. 妊娠高血圧腎症, 母体炎症

Research Areas 2

  1. Life Science / Obstetrics and gynecology

  2. Life Science / Embryonic medicine and pediatrics

Current Research Project and SDGs 2

  1. 妊娠高血圧腎症と将来の心血管障害発症との関連性~エピジェネティクスの観点より

  2. 妊娠高血圧腎症妊婦から出生した児におけるDOHaD仮説の検証と早期介入への戦略

Research History 3

  1. Nagoya University   Assistant Professor

    2017.4

  2. Nagoya University

    2013.4 - 2017.3

  3. 愛知県厚生農業協同組合連合会 安城更生病院   産婦人科

    2006.4 - 2013.3

Education 1

  1. Nagoya University

    1999.4 - 2006.3

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    Country: Japan

Professional Memberships 4

  1. 日本産科婦人科学会   指導医

  2. 日本周産期・新生児医学会   指導医

  3. 日本妊娠高血圧学会   総務役員

  4. 日本胎盤学会

Committee Memberships 1

  1. 日本妊娠高血圧学会   総務委員  

    2018.4   

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    Committee type:Academic society

Awards 3

  1. 学術集会長賞

    2019.11   日本産科麻酔学会  

  2. 学術奨励賞

    2018.12   尚和会  

  3. Y.W. Loke New Investigator Travel Award

    2014.9   International Federation of Placenta Associations  

 

Papers 79

  1. Mortality and neurological outcomes in extremely and very preterm infants born to mothers with hypertensive disorders of pregnancy Reviewed

    Nakamura Noriyuki, Ushida Takafumi, Nakatochi Masahiro, Kobayashi Yumiko, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Hayakawa Masahiro, Kajiyama Hiroaki, Kikkawa Fumitaka, Kotani Tomomi

    SCIENTIFIC REPORTS   Vol. 11 ( 1 )   2021.1

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    Authorship:Corresponding author  

    DOI: 10.1038/s41598-021-81292-7

    Web of Science

  2. Antenatal corticosteroids and preterm offspring outcomes in hypertensive disorders of pregnancy: A Japanese cohort study Reviewed

    Ushida Takafumi, Kotani Tomomi, Hayakawa Masahiro, Hirakawa Akihiro, Sadachi Ryo, Nakamura Noriyuki, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Kikkawa Fumitaka

    SCIENTIFIC REPORTS   Vol. 10 ( 1 )   2020.6

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    Authorship:Lead author  

    DOI: 10.1038/s41598-020-66242-z

    Web of Science

  3. Antenatal Corticosteroids and Outcomes in Preterm Twins Reviewed

    Ushida Takafumi, Kotani Tomomi, Sadachi Ryo, Hirakawa Akihiro, Hayakawa Masahiro, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Kikkawa Fumitaka

    OBSTETRICS AND GYNECOLOGY   Vol. 135 ( 6 ) page: 1387 - 1397   2020.6

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    Authorship:Lead author  

    DOI: 10.1097/AOG.0000000000003881

    Web of Science

  4. Persistence of risk factors associated with maternal cardiovascular disease following aberrant inflammation in rat pregnancy Reviewed International coauthorship

    Ushida Takafumi, Macdonald-Goodfellow Shannyn K., Quadri Allegra, Tse M. Yat, Winn Louise M., Pang Stephen C., Adams Michael A., Kotani Tomomi, Kikkawa Fumitaka, Graham Charles H.

    BIOLOGY OF REPRODUCTION   Vol. 97 ( 1 ) page: 143-152   2017.7

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/biolre/iox072

    Web of Science

    PubMed

  5. Predicting preterm birth within 2 weeks in asymptomatic women with a short cervix: Combined effects of cervicovaginal fluid cytokine levels and fetal fibronectin test

    Ohori, Y; Imai, K; Tano, S; Owaki, T; Miki, R; Nozaki, Y; Ushida, T; Kajiyama, H; Kotani, T

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH     2024.1

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  6. Sex-specific differences in head circumference of term singletons after assisted reproductive technology: a multicentre study in Japan

    Matsuo, S; Ushida, T; Tano, S; Imai, K; Yoshida, S; Yamashita, M; Kajiyama, H; Kotani, T

    REPRODUCTIVE BIOMEDICINE ONLINE   Vol. 47 ( 6 ) page: 103331   2023.12

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  7. New-onset postpartum hypertension in women without a history of hypertensive disorders of pregnancy: a multicenter study in Japan

    Ushida, T; Nakamura, N; Katsuki, S; Mizutani, H; Iitani, Y; Imai, K; Yoshida, S; Yamashita, M; Kajiyama, H; Kotani, T

    HYPERTENSION RESEARCH   Vol. 46 ( 12 ) page: 2583 - 2592   2023.12

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  8. Predictive performance of Shock Index for postpartum hemorrhage during cesarean delivery.

    Mizutani H, Ushida T, Ozeki K, Tano S, Iitani Y, Imai K, Nishiwaki K, Kajiyama H, Kotani T

    International journal of obstetric anesthesia     page: 103957   2023.11

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    Language:English  

    DOI: 10.1016/j.ijoa.2023.103957

    PubMed

  9. Interleukin-17A stimulation induces alterations in Microglial microRNA expression profiles

    Iitani, Y; Miki, R; Imai, K; Fuma, K; Ushida, T; Tano, S; Yoshida, K; Yokoi, A; Kajiyama, H; Kotani, T

    PEDIATRIC RESEARCH   Vol. 95 ( 1 ) page: 167 - 173   2023.9

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  10. Intrauterine exposure to chorioamnionitis and neuroanatomical alterations at term-equivalent age in preterm infants

    Nosaka, R; Ushida, T; Kidokoro, H; Kawaguchi, M; Shiraki, A; Iitani, Y; Imai, K; Nakamura, N; Sato, Y; Hayakawa, M; Natsume, J; Kajiyama, H; Kotani, T

    ARCHIVES OF GYNECOLOGY AND OBSTETRICS     2023.5

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  11. Antenatal corticosteroids-to-delivery interval associates cord blood S100B levels

    Fuma Kazuya, Kotani Tomomi, Ushida Takafumi, Imai Kenji, Iitani Yukako, Nakamura Noriyuki, Miki Rika, Katsuki Satoru, Kinoshita Fumie, Sato Yoshiaki, Hayakawa Masahiro, Kajiyama Hiroaki

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 49 ( 4 ) page: 1129 - 1136   2023.2

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  12. Clinical significances of Bishop score and vaginal bleeding to controlled-release dinoprostone delivery system (PROPESS) efficacy for cervical ripening: A retrospective single-center study in Japan

    Imai Kenji, Aoki Chieko, Tano Sho, Iitani Yukako, Nakamura Noriyuki, Ushida Takafumi, Kajiyama Hiroaki, Kotani Tomomi

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 49 ( 4 ) page: 1154 - 1160   2023.2

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  13. Trend changes in age-related body mass index gain after coronavirus disease 2019 pandemic in Japan: a multicenter retrospective cohort study

    Tano Sho, Kotani Tomomi, Ushida Takafumi, Iitani Yukako, Imai Kenji, Kinoshita Fumie, Kajiyama Hiroaki

    REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY   Vol. 21 ( 1 ) page: 7   2023.1

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  14. Prenatal diagnosis of distal 13q deletion syndrome in a fetus with esophageal atresia: a case report and review of the literature

    Kotani Tomomi, Tsuda Hiroyuki, Ito Yumiko, Nakamura Noriyuki, Ushida Takafumi, Imai Kenji, Iitani Yukako, Fuma Kazuya, Muramatsu Yukako, Hayakawa Masahiro, Kajiyama Hiroaki

    JOURNAL OF MEDICAL CASE REPORTS   Vol. 16 ( 1 ) page: 481   2022.12

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  15. Antenatal prediction models for outcomes of extremely and very preterm infants based on machine learning

    Ushida Takafumi, Kotani Tomomi, Baba Joji, Imai Kenji, Moriyama Yoshinori, Nakano-Kobayashi Tomoko, Iitani Yukako, Nakamura Noriyuki, Hayakawa Masahiro, Kajiyama Hiroaki

    ARCHIVES OF GYNECOLOGY AND OBSTETRICS     2022.12

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  16. A case of non-immune hydrops fetalis with maternal mirror syndrome diagnosed by trio-based exome sequencing: An autopsy case report and literature review

    Tano Sho, Kotani Tomomi, Yoshihara Masato, Nakamura Noriyuki, Matsuo Seiko, Ushida Takafumi, Imai Kenji, Ito Miharu, Oka Yasuyoshi, Sato Emi, Hayashi Shin, Ogi Tomoo, Kajiyama Hiroaki

    MOLECULAR GENETICS AND METABOLISM REPORTS   Vol. 33   page: 100925   2022.12

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  17. Aberrant inflammation in rat pregnancy leads to cardiometabolic alterations in their offspring and intrauterine growth restriction in the F2 generation

    Ushida Takafumi, Cotechini Tiziana, Protopapas Nicole, Atallah Aline, Collyer Charlotte, Toews Alexa J., Macdonald-Goodfellow Shannyn K., Tse M. Yat, Winn Louise M., Pang Stephen C., Adams Michael A., Othman Maha, Kotani Tomomi, Kajiyama Hiroaki, Graham Charles H.

    JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE   Vol. 13 ( 6 ) page: 706 - 718   2022.12

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  18. Antenatal corticosteroids and outcomes of small for gestational age infants born at 24-31 gestational weeks: a population-based propensity score matching analysis

    Ushida Takafumi, Nakatochi Masahiro, Kobayashi Yumiko, Nakamura Noriyuki, Fuma Kazuya, Iitani Yukako, Imai Kenji, Sato Yoshiaki, Hayakawa Masahiro, Kajiyama Hiroaki, Kotani Tomomi, Japan Neonatal Research Network Of

    ARCHIVES OF GYNECOLOGY AND OBSTETRICS     2022.11

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  19. Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells

    Aoki Chieko, Imai Kenji, Mizutani Teruyuki, Sugiyama Daisuke, Miki Rika, Koya Yoshihiro, Kobayashi Tomoko, Ushida Takafumi, Iitani Yukako, Nakamura Noriyuki, Owaki Taro, Nishikawa Hiroyoshi, Toyokuni Shinya, Kajiyama Hiroaki, Kotani Tomomi

    LIFE SCIENCES   Vol. 308   page: 120955   2022.11

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  20. 5p deletion with congenital diaphragmatic hernia: a case report

    Kotani Tomomi, Ushida Takafumi, Nakamura Noriyuki, Imai Kenji, Iitani Yukako, Tano Sho, Iwagaki Shigenori, Takahashi Yuichiro, Ito Miharu, Hayakawa Masahiro, Kajiyama Hiroaki

    JOURNAL OF MEDICAL CASE REPORTS   Vol. 16 ( 1 ) page: 390   2022.10

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  21. Optimal annual body mass index change for preventing spontaneous preterm birth in a subsequent pregnancy

    Tano Sho, Kotani Tomomi, Ushida Takafumi, Yoshihara Masato, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Iitani Yukako, Kinoshita Fumie, Yoshida Shigeru, Yamashita Mamoru, Kishigami Yasuyuki, Oguchi Hidenori, Kajiyama Hiroaki

    SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page: 17502   2022.10

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  22. DEVELOPING OF A NOVEL THERAPEUTIC AGENT FOR FGR THROUGH DRUG REPOSITIONING

    Tano Sho, Kotani Tomomi, Ushida Takafumi, Nakamura Noriyuki, Iitani Yukako, Yoshihara Masato, Imai Kenji, Kajiyama Hiroaki

    PLACENTA   Vol. 128   page: 124 - 124   2022.10

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  23. Severe Congenital Diaphragmatic Hernia With Trisomy 9: A Case Report and Review of the Literature

    Fuma Kazuya, Kotani Tomomi, Nakamura Noriyuki, Ushida Takafumi, Kajiyama Hiroaki

    CUREUS JOURNAL OF MEDICAL SCIENCE   Vol. 14 ( 8 ) page: e28395   2022.8

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  24. Impact of hypertensive disorders of pregnancy on respiratory outcomes in extremely and very preterm infants: A population-based study in Japan

    Ushida Takafumi, Nakamura Noriyuki, Nakatochi Masahiro, Kobayashi Yumiko, Sato Yoshiaki, Iitani Yukako, Imai Kenji, Nakano-Kobayashi Tomoko, Hayakawa Masahiro, Kajiyama Hiroaki, Kotani Tomomi

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 29   page: 54 - 60   2022.8

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  25. Machine learning prediction models for postpartum depression: A multicenter study in Japan

    Matsuo Seiko, Ushida Takafumi, Emoto Ryo, Moriyama Yoshinori, Iitani Yukako, Nakamura Noriyuki, Imai Kenji, Nakano-Kobayashi Tomoko, Yoshida Shigeru, Yamashita Mamoru, Matsui Shigeyuki, Kajiyama Hiroaki, Kotani Tomomi

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 7 ) page: 1775 - 1785   2022.7

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  26. Reassessing the duration of each stage of labor and their relation to postpartum hemorrhage in the current Japanese population

    Ushida Takafumi, Matsuo Seiko, Nakamura Noriyuki, Iitani Yukako, Imai Kenji, Nakano-Kobayashi Tomoko, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 7 ) page: 1760 - 1767   2022.7

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  27. The Possible Effects of Zinc Supplementation on Postpartum Depression and Anemia

    Aoki Chieko, Imai Kenji, Owaki Taro, Kobayashi-Nakano Tomoko, Ushida Takafumi, Iitani Yukako, Nakamura Noriyuki, Kajiyama Hiroaki, Kotani Tomomi

    MEDICINA-LITHUANIA   Vol. 58 ( 6 )   2022.6

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  28. Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb)

    Maki Shintaro, Tanaka Hiroaki, Takakura Sho, Nii Masafumi, Tanaka Kayo, Ogura Toru, Kotera Mayumi, Nishimura Yuki, Tamaru Satoshi, Ushida Takafumi, Tanaka Yasuhiro, Kikuchi Norihiko, Kinjo Tadatsugu, Kawamura Hiroshi, Takano Mayumi, Nakamura Koji, Suga Sachie, Kasai Michi, Yasui Osamu, Nagao Kenji, Maegawa Yuka, Kotani Tomomi, Endo Masayuki, Yasuhi Ichiro, Aoki Shigeru, Aoki Yoichi, Yoshida Yoshio, Nakata Masahiko, Sekizawa Akihiko, Ikeda Tomoaki

    BMJ OPEN   Vol. 12 ( 6 ) page: e054925   2022.6

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  29. Intrauterine exposure to hypertensive disorders of pregnancy and postnatal growth in extremely and very preterm infants

    Ushida Takafumi, Kotani Tomomi, Nakatochi Masahiro, Kobayashi Yumiko, Nakamura Noriyuki, Imai Kenji, Iitani Yukako, Nakano-Kobayashi Tomoko, Hayakawa Masahiro, Kajiyama Hiroaki

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 28   page: 174 - 179   2022.6

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  30. Pregnancy Outcomes in Women with Thyroid Diseases.

    Kotani T, Imai K, Ushida T, Moriyama Y, Nakano-Kobayashi T, Osuka S, Tsuda H, Sumigama S, Yamamoto E, Kinoshita F, Hirakawa A, Iwase A, Kikkawa F, Kajiyama H

    JMA journal   Vol. 5 ( 2 ) page: 216 - 223   2022.4

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    Language:English  

    DOI: 10.31662/jmaj.2021-0191

    PubMed

  31. Possible Repositioning of an Oral Anti-Osteoporotic Drug, Ipriflavone, for Treatment of Inflammatory Arthritis via Inhibitory Activity of KIAA1199, a Novel Potent Hyaluronidase

    Koike Hiroshi, Nishida Yoshihiro, Shinomura Tamayuki, Ohkawara Bisei, Ohno Kinji, Zhuo Lisheng, Kimata Koji, Ushida Takahiro, Imagama Shiro

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 23 ( 8 )   2022.4

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  32. Annual Body Mass Index Gain and Risk of Gestational Diabetes Mellitus in a Subsequent Pregnancy

    Tano Sho, Kotani Tomomi, Ushida Takafumi, Yoshihara Masato, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Iitani Yukako, Kinoshita Fumie, Yoshida Shigeru, Yamashita Mamoru, Kishigami Yasuyuki, Oguchi Hidenori, Kajiyama Hiroaki

    FRONTIERS IN ENDOCRINOLOGY   Vol. 13   page: 815390   2022.3

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  33. Assessment of placental abruption with diffusion-weighted imaging

    Mizutani Teruyuki, Kotani Tomomi, Kato Noriko, Imai Kenji, Ushida Takafumi, Nakano-Kobayashi Tomoko, Kinoshita Yoshimi, Ito Masato, Kinoshita Fumie, Yamamuro Osamu, Kajiyama Hiroaki

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH     2022.2

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  34. Pre-pregnancy sleep duration and postpartum depression: a multicenter study in Japan

    Matsuo Seiko, Ushida Takafumi, Iitani Yukako, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

    ARCHIVES OF WOMENS MENTAL HEALTH   Vol. 25 ( 1 ) page: 181 - 189   2022.2

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  35. Prevalence and risk factors of labor-onset hypertension: A multicenter study in Japan

    Ushida Takafumi, Kotani Tomomi, Imai Kenji, Nakano-Kobayashi Tomoko, Iitani Yukako, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 26   page: 48 - 53   2021.12

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  36. Hypertensive disorders of pregnancy and alterations in brain metabolites in preterm infants: A multi-voxel proton MR spectroscopy study

    Katsuki Satoru, Ushida Takafumi, Kidokoro Hiroyuki, Nakamura Noriyuki, Iitani Yukako, Fuma Kazuya, Imai Kenji, Nakano-Kobayashi Tomoko, Sato Yoshiaki, Hayakawa Masahiro, Natsume Jun, Kajiyama Hiroaki, Kotani Tomomi

    EARLY HUMAN DEVELOPMENT   Vol. 163   page: 105479   2021.12

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  37. Annual body mass index gain and risk of hypertensive disorders of pregnancy in a subsequent pregnancy

    Tano Sho, Kotani Tomomi, Ushida Takafumi, Yoshihara Masato, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Iitani Yukako, Kinoshita Fumie, Yoshida Shigeru, Yamashita Mamoru, Kishigami Yasuyuki, Oguchi Hidenori, Kajiyama Hiroaki

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 22519   2021.11

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  38. Manual removal of the placenta and postpartum hemorrhage: A multicenter retrospective study

    Fujita Kei, Ushida Takafumi, Imai Kenji, Nakano-Kobayashi Tomoko, Iitani Yukako, Matsuo Seiko, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kotani Tomomi

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 47 ( 11 ) page: 3867 - 3874   2021.11

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  39. Upregulation of ENDOU in cytotrophoblasts from placenta complicated with preeclampsia and fetal growth restriction

    Nomoto Masataka, Kotani Tomomi, Miki Rika, Ushida Takafumi, Imai Kenji, Iitani Yukako, Tano Sho, Wang Jingwen, Moriyama Yoshinori, Kobayashi Tomoko, Mimura Nobuko, Iriyama Takayuki, Kikkawa Fumitaka, Kajiyama Hiroaki

    JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   Vol. 69 ( 3 ) page: 280 - 285   2021.11

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  40. TRANSGENERATIONAL EFFECTS OF ABERRANT INFLAMMATION IN RAT PREGNANCY

    Atallah Aline, Ushida Takafumi, Protopapas Nicole, Macdonald-Goodfellow Shannyn, Graham Charles, Cotechini Tiziana

    PLACENTA   Vol. 112   page: E39 - E39   2021.9

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    Language:Japanese  

    Web of Science

  41. Current Issues within the Perinatal Mental Health Care System in Aichi Prefecture, Japan: A Cross-Sectional Questionnaire Survey

    Fujita Kei, Kotani Tomomi, Moriyama Yoshinori, Ushida Takafumi, Imai Kenji, Kobayashi-Nakano Tomoko, Kato Noriko, Kano Takeo, Kikkawa Fumitaka, Kajiyama Hiroaki

    INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH   Vol. 18 ( 17 )   2021.9

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  42. Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia

    Miura Mayo, Imai Kenji, Tsuda Hiroyuki, Miki Rika, Tano Sho, Ito Yumiko, Hirako-Takamura Shima, Moriyama Yoshinori, Ushida Takafumi, Iitani Yukako, Nakano-Kobayashi Tomoko, Toyokuni Shinya, Kajiyama Hiroaki, Kotani Tomomi

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 22 ( 17 )   2021.9

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  43. Impact of maternal hypertensive disorders of pregnancy on brain volumes at term-equivalent age in preterm infants: A voxel-based morphometry study

    Ushida Takafumi, Kidokoro Hiroyuki, Nakamura Noriyuki, Katsuki Satoru, Imai Kenji, Nakano-Kobayashi Tomoko, Moriyama Yoshinori, Sato Yoshiaki, Hayakawa Masahiro, Natsume Jun, Kajiyama Hiroaki, Kotani Tomomi

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 25   page: 143 - 149   2021.8

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  44. Antenatal prediction models for short- and medium-term outcomes in preterm infants

    Ushida Takafumi, Moriyama Yoshinori, Nakatochi Masahiro, Kobayashi Yumiko, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Hayakawa Masahiro, Kajiyama Hiroaki, Kotani Tomomi

    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA   Vol. 100 ( 6 ) page: 1089 - 1096   2021.6

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  45. Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders

    Ushida Takafumi, Kotani Tomomi, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Kinoshita Fumie, Nakamura Noriyuki, Iitani Yukako, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 24   page: 73 - 78   2021.6

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  46. Assessment of myocardial performance index in late-onset fetal growth restriction

    Tran Thao Nguyen Nguyen, Kotani Tomomi, Imai Kenji, Ushida Takafumi, Moriyama Yoshinori, Kobayashi Tomoko, Niimi Kaoru, Sumigama Seiji, Yamamoto Eiko, Van Duc Vo, Minh Tam Le, Lam Huong Le, Dac Nguyen Nguyen, Vu Quoc Huy Nguyen, Quang Vinh Truong, Ngoc Thanh Cao, Kikkawa Fumitaka

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 2 ) page: 259 - 268   2021.5

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  47. Postpartum alterations following inflammation in rat pregnancy: a discovery proteomic analysis

    Ushida Takafumi, Kotani Tomomi, Moriyama Yoshinori, Hindmarch Charles C. T., Cotechini Tiziana, Imai Kenji, Nakano-Kobayashi Tomoko, Kajiyama Hiroaki, Graham Charles H.

    REPRODUCTION   Vol. 161 ( 5 ) page: 513 - 522   2021.5

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  48. Vitamin D improves pulmonary function in a rat model for congenital diaphragmatic hernia Reviewed

    Ito Yumiko, Tsuda Hiroyuki, Imai Kenji, Miki Rika, Miura Mayo, Tachi Asuka, Tano Sho, Hirako-Takamura Shima, Moriyama Yoshinori, Ushida Takafumi, Kobayashi Tomoko, Sumigama Seiji, Kajiyama Hiroaki, Kikkawa Fumitaka, Kotani Tomomi

    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   Vol. 700   2021.3

  49. Trisomy 5p with bilateral congenital diaphragmatic hernia: a case report

    Nakamura Noriyuki, Ushida Takafumi, Moriyama Yoshinori, Imai Kenji, Nakano-Kobayashi Tomoko, Osuka Satoko, Goto Maki, Kajiyama Hiroaki, Asada Hideyuki, Hayakawa Masahiro, Kotani Tomomi

    JOURNAL OF MEDICAL CASE REPORTS   Vol. 15 ( 1 ) page: 114   2021.3

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  50. Maternal low birth weight and hypertensive disorders of pregnancy

    Ushida Takafumi, Kotani Tomomi, Kinoshita Fumie, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

    PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH   Vol. 23   page: 5 - 10   2021.3

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  51. Shock Index and Postpartum Hemorrhage in Vaginal Deliveries: A Multicenter Retrospective Study

    Ushida Takafumi, Kotani Tomomi, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki, Kikkawa Fumitaka

    SHOCK   Vol. 55 ( 3 ) page: 332 - 337   2021.3

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  52. Liver transaminase levels during pregnancy: a Japanese multicenter study Reviewed

    Ushida Takafumi, Kotani Tomomi, Kinoshita Fumie, Imai Kenji, Nakano-Kobayashi Tomoko, Nakamura Noriyuki, Moriyama Yoshinori, Yoshida Shigeru, Yamashita Mamoru, Kajiyama Hiroaki

    JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE     2021.2

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    Authorship:Lead author  

    DOI: 10.1080/14767058.2021.1892633

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  53. Multiple cytokine analysis in gastroschisis: Association with adverse outcomes including fetal brain damage Reviewed

    Owaki Taro, Imai Kenji, Miki Rika, Niwa Yuri, Kotani Tomomi, Nakano-Kobayashi Tomoko, Ushida Takafumi, Kajiyama Hiroaki

    CYTOKINE   Vol. 138   2021.2

  54. Forced expression of KIAA1199, a novel hyaluronidase, inhibits tumorigenicity of low-grade chondrosarcoma

    Koike Hiroshi, Nishida Yoshihiro, Shinomura Tamayuki, Zhuo Lisheng, Hamada Shunsuke, Ikuta Kunihiro, Ito Kan, Kimata Koji, Ushida Takahiro, Ishiguro Naoki

    JOURNAL OF ORTHOPAEDIC RESEARCH   Vol. 38 ( 9 ) page: 1942 - 1951   2020.9

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  55. A proteome signature of umbilical cord serum associated with congenital diaphragmatic hernia.

    Tachi A, Moriyama Y, Tsuda H, Miki R, Ushida T, Miura M, Ito Y, Imai K, Nakano-Kobayashi T, Hayakawa M, Kikkawa F, Kotani T

    Nagoya journal of medical science   Vol. 82 ( 2 ) page: 345 - 354   2020.5

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    DOI: 10.18999/nagjms.82.2.345

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  56. Determination of the cytokine levels in fetal pleural effusion and their association with fetal/neonatal findings

    Imai Kenji, Kotani Tomomi, Tsuda Hiroyuki, Kobayashi Tomoko, Ushida Takafumi, Moriyama Yoshinori, Kikkawa Fumitaka

    CYTOKINE   Vol. 127   2020.3

  57. Adverse effects of endometriosis on pregnancy: a case-control study Reviewed

    Miura Mayo, Ushida Takafumi, Imai Kenji, Wang Jingwen, Moriyama Yoshinori, Nakano-Kobayashi Tomoko, Osuka Satoko, Kikkawa Fumitaka, Kotani Tomomi

    BMC PREGNANCY AND CHILDBIRTH   Vol. 19 ( 1 )   2019.10

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    DOI: 10.1186/s12884-019-2514-1

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  58. A pitfall in diagnosing fetal abdominal lymphangioma: A report of two cases Reviewed

    Niwa Yuri, Imai Kenji, Kotani Tomomi, Nakano Tomoko, Ushida Takafumi, Moriyama Yoshinori, Kikkawa Fumitaka

    JOURNAL OF CLINICAL ULTRASOUND   Vol. 47 ( 8 ) page: 494 - 496   2019.10

  59. Feasibility of using a handheld tissue hardness meter to quantify uterine contractions and its clinical application for obstetric bleeding management Reviewed

    Imai Kenji, Kotani Tomomi, Ushida Takafumi, Moriyama Yoshinori, Nakano Tomoko, Kikkawa Fumitaka

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY   Vol. 39 ( 6 ) page: 757 - 762   2019.8

  60. ABERRANT INFLAMMATION IN RAT PREGNANCY CONTRIBUTES TO RISK FACTORS ASSOCIATED WITH CARDIOVASCULAR DISEASE AND PREGNANCY COMPLICATIONS IN SUBSEQUENT GENERATIONS

    Protopapas Nicole, Ushida Takafumi, Macdonald-Goodfellow Shannyn K., Graham Charles H.

    PLACENTA   Vol. 83   page: E76 - E76   2019.8

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  61. Relationship between cytokine profiles of cord blood and cord S100B levels in preterm infants.

    Niwa Y, Imai K, Kotani T, Miki R, Nakano T, Ushida T, Moriyama Y, Kikkawa F

    Early human development   Vol. 129   page: 65-70   2019.2

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    DOI: 10.1016/j.earlhumdev.2019.01.013

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  62. The role of E2F8 in the human placenta

    Mizuno Masako, Miki Rika, Moriyama Yoshinori, Ushida Takafumi, Imai Kenji, Niimi Kaoru, Nakano Tomoko, Tsuda Hiroyuki, Sumigama Seiji, Yamamoto Eiko, Senga Takeshi, Iwase Akira, Kikkawa Fumitaka, Kotani Tomomi

    MOLECULAR MEDICINE REPORTS   Vol. 19 ( 1 ) page: 293-301   2019.1

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    DOI: 10.3892/mmr.2018.9617

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  63. Clinical utility and limitations of FibCare (R) for the rapid measurement of fibrinogen concentrations: The first clinical experience

    Imai Kenji, Kotani Tomomi, Nakano Tomoko, Ushida Takafumi, Kikkawa Fumitaka

    TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY   Vol. 57 ( 6 ) page: 899-900   2018.12

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    DOI: 10.1016/j.tjog.2018.10.024

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  64. A rare pseudo tumour in the extraembryonic coelom in first trimester of pregnancy: ultrasound and pathology.

    Sumigama S, Enomoto A, Matsukawa S, Ushida T, Imai K, Nakano T, Kotani T, Kikkawa F

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     page: 1-2   2018.11

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    DOI: 10.1080/01443615.2018.1511971

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  65. DRUG REPOSITIONING FOR SEARCH THE DRUG TO SUPPORT PLACENTAL GROWTH

    Nomoto Masataka, Kotani Tomomi, Mizutani Teruyuki, Moriyama Yoshinori, Ushida Takefumi, Imai Kenji, Nakano Tomoko, Kikkawa Fumitaka

    PLACENTA   Vol. 69   page: E21-E21   2018.9

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  66. The rate of neonatal respiratory distress syndrome/transient tachypnea in the newborn and the amniotic lamellar body count in twin pregnancies compared with singleton pregnancies

    Tsuda Hiroyuki, Kotani Tomomi, Nakano Tomoko, Imai Kenji, Ushida Takafumi, Hirakawa Akihiro, Kinoshita Fumie, Takahashi Yuichiro, Iwagaki Shigenori, Kikkawa Fumitaka

    CLINICA CHIMICA ACTA   Vol. 484   page: 293-297   2018.9

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    DOI: 10.1016/j.cca.2018.06.015

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  67. The impact of fertility treatment on the neonatal respiratory outcomes and amniotic lamellar body counts in twin pregnancies

    Tsuda Hiroyuki, Kotani Tomomi, Nakano Tomoko, Imai Kenji, Ushida Takafumi, Hirakawa Akihiro, Kinoshita Fumie, Takahashi Yuichiro, Iwagaki Shigenori, Kikkawa Fumitaka

    CLINICA CHIMICA ACTA   Vol. 484   page: 192-196   2018.9

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    DOI: 10.1016/j.cca.2018.05.060

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  68. PLACENTAL PROTEOMIC ANALYSIS OF PLACENTA ACCRETA

    Moriyama Yoshinori, Sumigama Seiji, Mizutani Teruyuki, Nomoto Masataka, Ushida Takafumi, Imai Kenji, Nakano Tomoko, Kotani Tomomi, Kikkawa Fumitaka

    PLACENTA   Vol. 69   page: E74-E75   2018.9

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  69. PLACENTAL MORPHOLOGY AND PREGNANCY COMPLICATIONS IN FULLTERM PREGNANCY

    Ushida Takafumi, Mizutani Teruyuki, Nomoto Masataka, Moriyama Yoshinori, Imai Kenji, Nakano Tomoko, Kotani Tomomi, Kikkawa Fumitaka

    PLACENTA   Vol. 69   page: E76-E76   2018.9

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  70. EFFECTOR REGULATORY. CELLS IN THE DECIDUA DECREASE IN LABOR

    Mizutani Teruyuki, Kotani Tomomi, Ushida Takafumi, Imai Kenji, Nakano Tomoko, Moriyama Yoshinori, Nomoto Masataka, Kikkawa Fumitaka

    PLACENTA   Vol. 69   page: E69-E69   2018.9

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  71. Altered proteomic profile in umbilical arterial serum from mothers with schizophrenia

    Moriyama Yoshinori, Kotani Tomomi, Ushida Takafumi, Imai Kenji, Nakano Tomoko, Tsuda Hiroyuki, Kikkawa Fumitaka

    SCHIZOPHRENIA RESEARCH   Vol. 197   page: 615-617   2018.7

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    DOI: 10.1016/j.schres.2018.02.024

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  72. Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model

    Imai Kenji, Kotani Tomomi, Tsuda Hiroyuki, Nakano Tomoko, Ushida Takafumi, Iwase Akira, Nagai Taku, Toyokuni Shinya, Suzumura Akio, Kikkawa Fumitaka

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 9221   2018.6

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    DOI: 10.1038/s41598-018-27626-4

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  73. Effect of molecular hydrogen on uterine inflammation during preterm labour

    Nakano Tomoko, Kotani Tomomi, Imai Kenji, Iitani Yukako, Ushida Takafumi, Tsuda Hiroyuki, Li Hua, Iwase Akira, Toyokuni Shinya, Kikkawa Fumitaka

    BIOMEDICAL REPORTS   Vol. 8 ( 5 ) page: 454-460   2018.5

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    DOI: 10.3892/br.2018.1082

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  74. Maternal protein S activity is associated with massive hemorrhage during caesarean section: retrospective case-control study. Reviewed

    Imai K, Kotani T, Nakano T, Ushida T, Hirakawa A, Kikkawa F

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     page: 1-181   2018.2

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    DOI: 10.1080/14767058.2018.1443067

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  75. The expression of Toll-like receptor 5 in preterm histologic chorioamnionitis.

    Moroi H, Kotani T, Miki R, Tsuda H, Mizuno M, Ito Y, Ushida T, Imai K, Nakano T, Li H, Sumigama S, Yamamoto E, Iwase A, Kikkawa F

    Journal of clinical biochemistry and nutrition   Vol. 62 ( 1 ) page: 63-67   2018.1

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    DOI: 10.3164/jcbn.16-103

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  76. Discordant Relationship Between Evaluation of Facial Expression and Subjective Pain Rating Due to the Low Pain Magnitude.

    Hayashi K, Ikemoto T, Ueno T, Arai YP, Shimo K, Nishihara M, Suzuki S, Ushida T

    Basic and clinical neuroscience   Vol. 9 ( 1 ) page: 43 - 50   2018.1

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    DOI: 10.29252/NIRP.BCN.9.1.43

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  77. ABERRANT MATERNAL INFLAMMATION IN PREGNANCY LEADS TO PERSISTENCE OF RISK FACTORS FOR CARDIOVASCULAR DISEASE IN THE OFFSPRING

    Ushida Takafumi, Macdonald-Goodfellow Shannyn, Tse M. Yat, Winn Louise, Pang Stephen, Adams Michael, Kotani Tomomi, Kikkawa Fumitaka, Graham Charles

    PLACENTA   Vol. 57   page: 243-243   2017.9

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    DOI: 10.1016/j.placenta.2017.07.074

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  78. PERSISTENCE OF RISK FACTORS ASSOCIATED WITH MATERNAL CARDIOVASCULAR DISEASE FOLLOWING ABERRANT INFLAMMATION IN RAT PREGNANCY

    Ushida Takafumi, Macdonald-Goodfellow Shannyn, Quadri Allegra, Tse M. Yat, Winn Louise, Pang Stephen, Adams Michael, Kotani Tomomi, Kikkawa Fumitaka, Graham Charles

    PLACENTA   Vol. 57   page: 279-279   2017.9

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    DOI: 10.1016/j.placenta.2017.07.180

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  79. A large mediastinal tumour invading into the liver with foetal hydrops: A rare case of infantile myofibromatosis Reviewed

    Ushida Takafumi, Tsuda Hiroyuki, Takahara Taishi, Takahashi Yuichiro, Kotani Tomomi, Kikkawa Fumitaka

    JOURNAL OF OBSTETRICS AND GYNAECOLOGY   Vol. 37 ( 6 ) page: 821-823   2017

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    DOI: 10.1080/01443615.2017.1303468

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. Interdisciplinary research toward the feto-maternal interface environmental strategies with targeted proteomics

    Grant number:23KK0157  2023.9 - 2027.3

    Grants-in-Aid for Scientific Research  Fund for the Promotion of Joint International Research (International Collaborative Research)

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    Authorship:Coinvestigator(s) 

  2. 妊娠高血圧症候群による児の神経学的後障害の病態解明と先制医療への戦略

    Grant number:22K16857  2022.4 - 2025.3

    科学研究費助成事業  若手研究

    牛田 貴文

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    Authorship:Principal investigator 

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    妊娠高血圧症候群は妊婦の5~10%に発症し、高血圧や蛋白尿を特徴とする疾患である。妊娠高血圧症候群を発症した母から出生した児は、脳性麻痺や運動障害のみならず自閉症スペクトラム障害、注意欠陥多動性障害などの神経学的後障害のリスクが上昇することが報告されている。本研究では妊娠高血圧症候群による胎内での児の脳神経・免疫細胞への影響を解析する。また、MRI画像を用いた解析や日本の約200施設の早産児データベースを用いた解析により、神経学的後障害のハイリスクとなる児をどのように早期に見つけ出すかという臨床上の課題に取り組む。