Updated on 2024/08/01

写真a

 
ARIYASU Shinya
 
Organization
Graduate School of Science Assistant Professor
Graduate School
Graduate School of Science
Undergraduate School
School of Science Department of Chemistry
Title
Assistant Professor

Degree 1

  1. Doctor of Science ( 2010.3   Tokyo University of Science ) 

Research Interests 4

  1. Chemical biology

  2. Bioorganic chemistry

  3. Enzymatic chemistry

  4. Bioinorganic chemistry

Research Areas 1

  1. Nanotechnology/Materials / Inorganic/coordination chemistry  / bioinorganic chemistry

Current Research Project and SDGs 1

  1. Direct hydroxylation of non natural substrates by cytochrome P450s with decoy molecules

Research History 4

  1. Nagoya University   Graduate School of Science   Assistant Professor

    2019.4

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    Country:Japan

  2. Nagoya University   Graduate School of Science   Designated assistant professor

    2016.9 - 2019.3

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    Country:Japan

  3. Nanyang Technological University   School of Physical and Mathematical Science   Researcher

    2014.6 - 2016.9

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    Country:Singapore

  4. Tokyo University of Science   Center for Technologies against Cancer   Researcher

    2010.4 - 2014.5

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    Country:Japan

Education 3

  1. Tokyo University of Science   Faculty of Science   Department of Chemistry

    2006.4 - 2010.3

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    Country: Japan

  2. Tokyo University of Science   Faculty of Science   Department of Chemistry

    2004.4 - 2006.3

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    Country: Japan

  3. Tokyo University of Science   Faculty of Science   Department of Chemistry

    2000.4 - 2004.3

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    Country: Japan

Professional Memberships 7

  1. フロンティア生命化学研究会

  2. 日本ケミカルバイオロジー学会

  3. 日本薬学会

  4. 日本化学会生体機能関連化学部会   若手会幹事

  5. 錯体化学会

  6. 日本化学会

  7. 日本農芸化学会

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Awards 3

  1. 第16回わかしゃち奨励賞 基礎研究部門優秀賞

    2021.11   令和3年度愛知県若手研究者イノベーション創出奨励事業   不活性気体を調節因子とする酵素反応制御技術の創製

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    Award type:Award from publisher, newspaper, foundation, etc. 

  2. 13th Tetrahedron Symposium Asia Edition Best Poster Prize

    2012.11   13th Tetrahedron Symposium Asia Edition  

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    Award type:Award from international society, conference, symposium, etc. 

  3. 東京理科大学理窓博士会学術奨励賞

    2011.9   東京理科大学理窓博士会  

 

Papers 34

  1. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules Reviewed

    Ariyasu, S; Yonemura, K; Kasai, C; Aiba, Y; Onoda, H; Shisaka, Y; Sugimoto, H; Tosha, T; Kubo, M; Kamachi, T; Yoshizawa, K; Shoji, O

    ACS Catalysis   Vol. 13 ( 13 ) page: 8613 - 8623   2023.6

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acscatal.3c01158

    Web of Science

  2. Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom

    Inaba, H; Shisaka, Y; Ariyasu, S; Sakakibara, E; Ueda, G; Aiba, Y; Shimizu, N; Sugimoto, H; Shoji, O

    RSC ADVANCES   Vol. 14 ( 13 ) page: 8829 - 8836   2024.3

  3. Influence of Solvents on Catalytic C-H Bond Oxidation by a Copper(II)-Alkylperoxo Complex Reviewed International coauthorship

    Lee, Y; Kim, B; Kim, S; Ng, EWH; Ariyasu, S; Shoji, O; Yoon, S; Hirao, H; Cho, J

    ACS CATALYSIS   Vol. 14 ( 5 ) page: 3524 - 3532   2024.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acscatal.3c05643

    Web of Science

  4. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 Exploiting Chemically Evolved Decoy Molecules

    Shoji, O; Ariyasu, S; Aiba, Y

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   Vol. 82 ( 5 ) page: 505 - 512   2024

  5. Highly selective hydroxylation of gaseous alkanes at the terminal position by wild-type CYP153A33 Reviewed

    Kodama, Y; Ariyasu, S; Karasawa, M; Aiba, Y; Shoji, O

    Catalysis Science & Technology   Vol. 13 ( 21 ) page: 6146 - 6152   2023.10

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d3cy00752a

    Web of Science

  6. Investigating the applicability of the CYP102A1-decoy-molecule system to other members of the CYP102A subfamily Reviewed International coauthorship

    Stanfield, JK; Onoda, H; Ariyasu, S; Kasai, C; Burfoot, EM; Sugimoto, H; Shoji, O

    Journal of Inorganic Biochemistry   Vol. 245   page: 112235   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jinorgbio.2023.112235

    Web of Science

    PubMed

  7. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations Reviewed

    Suzuki, K; Stanfield, JK; Omura, K; Shisaka, Y; Ariyasu, S; Kasai, C; Aiba, Y; Sugimoto, H; Shoji, O

    Angewandte Chemie-International Edition   Vol. 62 ( 13 ) page: e202215706   2023.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/anie.202215706

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    PubMed

  8. A P450 Harboring Manganese Protoporphyrin IX Generates a Manganese Analogue of Compound I by Activating Dioxygen Reviewed

    Omura, K; Aiba, Y; Suzuki, K; Ariyasu, S; Sugimoto, H; Shoji, O

    ACS Catalysis   Vol. 12 ( 18 ) page: 11108 - 11117   2022.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acscatal.2c0134511108

    Web of Science

  9. Expanding the applicability of cytochrome P450s and other haemoproteins Invited Reviewed

    Ariyasu Shinya, Stanfield Joshua Kyle, Aiba Yuichiro, Shoji Osami

    Current Opinion in Chemical Biology   Vol. 59   page: 155 - 163   2020.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.cbpa.2020.06.010

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  10. Systematic Evolution of Decoy Molecules for the Highly Efficient Hydroxylation of Benzene and Small Alkanes Catalyzed by Wild-Type Cytochrome P450BM3 Reviewed

    Yonemura Kai, Ariyasu Shinya, Stanfield Joshua Kyle, Suzuki Kazuto, Onoda Hiroki, Kasai Chie, Sugimoto Hiroshi, Aiba Yuichiro, Watanabe Yoshihito, Shoji Osami

    ACS Catalysis   Vol. 10 ( 16 ) page: 9136 - 9144   2020.8

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acscatal.0c01951

    Web of Science

  11. Molecular Design and Regulation of Metalloenzyme Activities through Two Novel Approaches: Ferritin and P450s Invited Reviewed

    Watanabe Yoshihito, Aiba Yuichiro, Ariyasu Shinya, Abe Satoshi

    Bulletin of the Chemical Society of Japan   Vol. 93 ( 3 ) page: 379 - 392   2020.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1246/bcsj.20190305

    Web of Science

  12. Development of a High-Pressure Reactor Based on Liquid-Flow Pressurisation to Facilitate Enzymatic Hydroxylation of Gaseous Alkanes Reviewed

    Ariyasu Shinya, Kodama Yusaku, Kasai Chie, Cong Zhiqi, Stanfield Joshua Kyle, Aiba Yuichiro, Watanabe Yoshihito, Shoji Osami

    ChemCatChem   Vol. 11 ( 19 ) page: 4709 - 4714   2019.10

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cctc.201901323

    Web of Science

  13. Simple and Convenient Method for the Isolation, Culture, and Recollection of Cancer Cells from Blood by Using Glass-Bead Filters Reviewed

    Babita Shashni, Hidehiko Matsuura, Riku Saito, Takuma Hirata, Shinya Ariyasu, Kenta Nomura, Hiroshi Takemura, Kazunori Akimoto, Naoyuki Aikawa, Atsuo Yasumori, Shin Aoki

    ACS Biomaterials Science & Engineering   Vol. 5   page: 438 - 452   2018.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsbiomaterials.8b01335

  14. Reconstitution of full-length P450BM3 with an artificial metal complex by utilising the transpeptidase Sortase A Reviewed

    Omura Keita, Aiba Yuichiro, Onoda Hiroki, Stanfield Joshua Kyle, Ariyasu Shinya, Sugimoto Hiroshi, Shiro Yoshitsugu, Shoji Osami, Watanabe Yoshihito

    Chemical Communications   Vol. 54 ( 57 ) page: 7892 - 7895   2018.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c8cc02760a

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    PubMed

  15. Size-based Differentiation of Cancer and Normal Cells by a Particle Size Analyzer Assisted by a Cell-recognition PC Software Reviewed

    Babita Shashni, Shinya Ariyasu, Reisa Takeda, Toshihiro Suzuki, Shota Shiina, Kazunori Akimoto, Takuto Maeda, Naoyuki Aikawa, Ryo Abe, Tomohiro Osaki, Norihiko Itoh, Shin Aoki

    Biological and Pharmaceutical Bulletin   Vol. 41   page: 7892 - 7895   2018.5

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    Language:English  

  16. Reconstitution of self-sufficient cytochrome P450 with artificial metal complexes

    Omura Keita, Aiba Yuichiro, Ariyasu Shinya, Shoji Osami, Sugimoto Hiroshi, Shiro Yoshitsugu, Watanabe Yoshihito

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   Vol. 255   page: .   2018.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    Web of Science

  17. Site-specific Dual Functionalization of Cysteine Residue in Peptides and Proteins with 2-Azidoacrylates Reviewed

    Shinya Ariyasu, Hirohito Hayashi, Bengang Xing, Shunsuke Chiba

    Bioconjugate Chemistry   Vol. 28   page: 897 - 902   2018.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  18. A chemical modulator of p53 transactivation that acts as a radioprotective agonist Reviewed

    Akinori Morita, Ippei Takahashi, Megumi Sasatani, Shin Aoki, Bing Wang, Shinya Ariyasu, Kaoru Tanaka, Tetsuji Yamaguchi, Akiko Sawa, Yurie Nishi, Tatsuro Teraoka, Shohei Ujita, Yosuke Kawate, Chihiro Yanagawa, Keiji Tanimoto, Atsushi Enomoto, Mitsuru Nenoi, Kenji Kamiya, Yasushi Nagata, Yoshio Hosoi, Toshiya Inaba

    Molecular Cancer Therapeutics   Vol. 17   page: 432 - 442   2017.8

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    Language:English  

  19. Investigation of Thermally Induced Cellular Ablation and Heat Response Triggered by Planar MoS2-based Nanocomposite Reviewed

    Shinya Ariyasu, Jing Mu, Xiao Zhang, Ying Huang, Edwin Kok Lee Yeow, Hua Zhang, Bengang Xing

    Bioconjugate Chemistry   Vol. 28   page: 1069 - 1076   2017.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  20. Glycopeptide Antibiotic Analogs for Selective Inactivation and Two-Photon Imaging of Vancomycin-Resistant Strains Reviewed

    Shinya Ariyasu, Pei Chui Too, Jing Mu, Chi Ching Goh, Yichen Ding, Ya Lin Tnay, Edwin Kok Lee Yeow, Liang Yang, Lai Guan Ng, Shunsuke Chiba, Bengang Xing

    Chemical Communications   Vol. 52   page: 4667 - 4670   2016.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  21. Development of a novel sulfonate ester-based prodrug strategy Reviewed

    Kengo Hanaya, Shohei Yoshioka, Shinya Ariyasu, Shin Aoki, Mitsuru Shoji, Takeshi Sugai

    Bioorganic & Medicinal Chemistry Letters   Vol. 26   page: 545 - 550   2015.11

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    Language:English   Publishing type:Research paper (scientific journal)  

  22. Enrichment of circulating tumor cells in tumor-bearing mouse blood by a deterministic lateral displacement microfluidic device Reviewed

    Hiromasa Okano, Tomoki Konishi, Toshihiro Suzuki, Takahiro Suzuki, Shinya Ariyasu, Shin Aoki, Masanori Hayase

    Biomedical Microdevices   Vol. 17   page: 1 - 11   2015.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  23. AS-2, a novel inhibitor of p53-dependent apoptosis, prevents apoptotic mitochondrial dysfunction in a transcription-independent manner and protects mice from a lethal dose of ionizing radiation Reviewed

    Akinori Morita, Shinya Ariyasu, Bing Wang, Tetsuo Asanuma, Takayoshi Onoda, Akiko Sawa, Kaoru Tanaka, Ippei Takahashi, Shotaro Togami, Mitsuru Nenoi, Toshiya Inaba, Shin Aoki

    Biochemical and Biophysical Research Communications   Vol. 450   page: 1498 - 1504   2014.7

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    Language:English   Publishing type:Research paper (scientific journal)  

  24. Design and Synthesis of 8-Hydroxyquinoline-based Radioprotective Agents Reviewed

    Shinya Ariyasu, Akiko Sawa, Akinori Morita, Kengo Hanaya, Misato Hoshi, Ippei Takahashi, Bing Wang and Shin Aoki

    Bioorganic & Medicinal Chemistry Letters   Vol. 22   page: 3891 - 3905   2014.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  25. Design, Synthesis and Photochemical Reactivation of Caged Prodrugs of 8-Hydroxyquinoline-based Enzyme Inhibitors Reviewed

    Shinya Ariyasu, Yuki Mizuseda, Kengo Hanaya, Shin Aoki

    Chemical and Pharmaceutical Bulletin   Vol. 62   page: 642 - 648   2014.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  26. Evaluation of Zinc (II) chelators for inhibiting p53-mediated apoptosis Reviewed

    Akinori Morita, Shinya Ariyasu, Soichiro Ohya, Ippei Takahashi, Bing Wang, Kaoru Tanaka, Takatoshi Uchida, Haruna Okazaki, Kengo Hanaya, Atsushi Enomoto, Mitsuru Nenoi, Masahiko Ikekita, Shin Aoki, Yoshio Hosoi

    Oncotarget   Vol. 4   page: 2439 - 2450   2013.11

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    Language:English   Publishing type:Research paper (scientific journal)  

  27. The Selective Capture and Collection of Live Target Cells Using a Silicon Wafer Device Modified with Antibodies via a Photocleavable Linker Reviewed

    Shinya Ariyasu, Kengo Hanaya, Eita Watanabe, Toshihiro Suzuki, Kazutaka Horie, Masanori Hayase, Ryo Abe, Shin Aoki

    Langmuir   Vol. 59   page: 13118 - 13126   2012.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  28. Photochemical Cleavage Reaction of 8-Quinolinyl Sulfonates That Are Halogenated and Nitrated at the 7-Position Reviewed

    Shinya Ariyasu, Kengo Hanaya, Megumi Tsunoda, Masanori Kitamura, Masanori Hayase, Ryo Abe, Shin Aoki

    Chemical and Pharmaceutical Bulletin   Vol. 59   page: 1355 - 1362   2011.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  29. Affinity Clusters: An Adenine-Coated Gold Cluster Binds to Thymine Loops in DNA. Reviewed

    Takeshi Yamamura, Shinya Ariyasu, Ryota Sakamoto

    Chemistry an Asian Journal   Vol. 6   page: 1761 - 1765   2011.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  30. Inorganic Bioconjugates of Gold Clusters and Nanoparticles -Briefly History and Recent Development- Invited

    Takeshi Yamamura, Shinya Ariyasu

    Bulletin of Japan Society of Coordination Chemistry   Vol. 55   page: 71 - 77   2010.2

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    Language:English   Publishing type:Research paper (scientific journal)  

  31. Alignment of Gold Clusters on DNA via a DNA-recognizing Zinc Finger-Metallothionein Fusion Protein Reviewed

    Shinya Ariyasu, Akira Onoda, Ryota Sakamoto, Takeshi Yamamura

    Bioconjugate Chemistry   Vol. 20   page: 2278 - 2285   2009.9

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  32. Minimal motif peptide structure of metzincin clan zinc peptidases in micelles Reviewed

    Akira Onoda, Takako Suzuki, Hiroaki Ishizuka, Shinya Ariyasu, Takeshi Yamamura

    Journal of Peptide Science   Vol. 15   page: 832 - 841   2009.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  33. Conjugation of Au11 Cluster with Cys-rich Peptides Containing the -Domain of Metallothionein Reviewed

    Shinya Ariyasu, Akira Onoda, Ryota Sakamoto, Takeshi Yamamura

    Dalton Transactions   Vol. 38   page: 3742 - 3747   2009.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  34. Circular Dichroism of Neutral Zinc Porphyrin-Oligonucleotide Conjugates Modified with Flexible Linker Reviewed

    Akira Onoda, Masahiro Igarashi, Satoshi Naganawa, Kiyomi Sasaki, Shinya Ariyasu, Takeshi Yamamura

    Bulletin of the Chemical Society of Japan   Vol. 82   page: 1280 - 1286   2009.2

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 6

  1. Bioinorganic Chemistry and Homogeneous Biomimetic Inorganic Catalysis

    Shoji, O.; Aiba, Y.; Ariyasu, S.; Onoda, H.(2.08 - Heme-containing proteins: Structures, functions, and engineering)

    Elsevier Ltd.  2023  ( ISBN:9780128231531

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    Responsible for pages:194-214   Language:English

  2. 水中有機化学反応プロセスの開発動向

    荘司長三, 有安真也, 愛場雄一郎( Role: Joint author ,  第22章デコイ分子によるシトクロムP450BM3の反応制御と水中での高難度水酸化反応)

    シーエムシー出版  2022 

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    Language:Japanese Book type:Scholarly book

  3. 酵素機能を化学的にハックする新規手法の開発、触媒年鑑:触媒技術の動向と展望 2021年版

    大村 慧太, 愛場 雄一郎, 有安 真也, 荘司 長三( Role: Joint author)

    一般社団法人触媒学会  2021 

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    Language:Japanese Book type:Scholarly book

  4. 気体資源の有効活用を目指した高圧反応装置の開発

    有安真也、荘司長三( Role: Joint author)

    シーエムシー出版  2020.3 

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    Responsible for pages:46-56   Language:Japanese Book type:Scholarly book

  5. シトクロムP450BM3 の誤作動状態を利用したガス状アルカンの直接水酸化

    有安真也、愛場雄一郎、荘司長三( Role: Joint author)

    日本エネルギー学会  2020 

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    Responsible for pages:147-154   Language:Japanese Book type:Scholarly book

  6. 8-quinolinol誘導体の化学反応と酵素阻害剤・バイオケミカルツールへの応用

    青木伸、有安真也、花屋賢悟、久松洋介、須貝威( Role: Joint author)

    有機合成化学協会  2016 

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    Language:Japanese Book type:Scholarly book

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MISC 6

  1. 名古屋大学、化学基礎原料のメタノール 常温で生成

    日本経済新聞電子版     2023.7

  2. 脱炭素の加速へ -メタン活用に新たな選択肢 ~酵素を”だまして”メタノールに変換する新技術

    荘司長三、有安真也、米村開

    名古屋大学プレスリリース     2023.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  3. 脱炭素の加速へ -メタン活用に新たな選択肢 ~酵素を”だまして”メタノールに変換する新技術

    日本の研究.com     2023.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  4. 「簡便な高圧反応装置 ガス状アルカンの水酸化向け HPLC転用、100気圧」

    化学工業新聞     2019.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  5. 「名大、反応性が極めて低い気体分子の化学変換の高効率化に成功」

    日本経済新聞(電子版)     2019.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  6. 「気体を安全に加圧可能な高圧反応装置の開発! ~不活性な気体資源の有効活用に道筋~」

    名古屋大学-JST共同発表プレスリリース     2019.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

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Presentations 45

  1. Catalytic Oxidation of Gaseous Alkanes by Wild-type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules International conference

    Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji

    23rd International Conference on Cytochrome P450  2023.9.28 

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    Event date: 2023.9

    Language:English   Presentation type:Poster presentation  

    Venue:Shizuoka Convention and Arts Center   Country:Japan  

  2. 合成分子で酵素の能力を引き出す技術の最前線 Invited

    有安真也

    第17回バイオ関連化学シンポジウム Graduate Student Session  2023.9.10 

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    Event date: 2023.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京理科大学野田キャンパス   Country:Japan  

  3. Catalytic Oxidation of Methane by Wild-type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules International conference

    Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji

    10th Asian Biological Inorganic Chemistry Conference (AsBIC)  2022.12.3 

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    Event date: 2022.11 - 2022.12

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Kobe International Center   Country:Japan  

  4. 化学的基質特異性変換を用いたシトクロムP450による非天然基質の化学変換 Invited

    有安真也

    日本農芸化学中部支部 第194回例会ミニシンポジウム  2022.11.26 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  5. 基質認識型擬似基質を用いたシトクロムP450による親水性化合物の位置、立体選択的水酸化技術の開発 Invited

    有安 真也, 高山 凌, 愛場 雄一郎, 荘司 長三

    第2回天野エンザイム酵素研究助成報告会  2022.11.18 

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    Event date: 2022.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋大学東山キャンパス   Country:Japan  

  6. 脂肪酸末端水酸化酵素CYP153の基質誤認識を利用した1級選択的ガス状アルカン水酸化

    有安 真也、児玉 侑朔、愛場 雄一郎、荘司 長三

    第31回金属の関与する生体関連反応シンポジウム  2022.6.19 

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    Event date: 2022.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:同志社大学京田田辺キャンパス   Country:Japan  

  7. Enzymatic Methane Hydroxylation by Cytochrome P450BM3 with Chemically Evolved Decoy Molecules

    Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji

    2021.9.18 

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    Event date: 2021.9

    Language:English   Presentation type:Oral presentation (general)  

  8. シトクロムP450を用いた高圧条件下ガス状アルカンの直接水酸化

    2有安真也、児玉侑朔、米村開、笠井千枝、愛場雄一郎、久保稔、當舎武彦、杉本宏、荘司長三

    第47回生体分子科学討論会  2021.6.5 

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    Event date: 2021.6

    Language:Japanese   Presentation type:Oral presentation (general)  

  9. Enzymatic Hydroxylation of Small Alkanes by P450BM3 with Decoy Molecules under High Pressure International conference

    Shinya Ariyasu, Yusaku Kodama, Kai Yonemura, Chie Kasai, Joshua Kyle Stanfield, Yuma Shisaka, Yuichiro Aiba, Yoshihito Watanabe, Osami Shoji

    The 4th IRCCS International Symposium "Multidimensional control over material structure and function”  2021.3.15 

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    Event date: 2021.3

    Language:English   Presentation type:Poster presentation  

  10. 合成分子による酵素の機能改変に基づく化学的生合成リデザイン Invited

    有安 真也

    新学術領域研究「生合成リデザイン」第9回公開シンポジウム  2020.11.14 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

  11. シトクロムP450による高難度ガス状アルカンの直接水酸化

    有安 真也、児玉 侑朔、米村 開、笠井 千枝、愛場 雄一郎、荘司 長三

    第14回バイオ関連化学シンポジウム  2020.9.8 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  12. 合成分子を用いた生体分子の機能制御と改変:シトクロムP450BM3の基質特異性変換とメタンの直接水酸化への応用 Invited

    有安 真也

    第180回名古屋市立大学薬学談話会  2018.10.5 

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    Event date: 2018.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋市立大学  

  13. Catalytic Oxidation of Methane by Cytochrome P450BM3 Variants with Decoy Molecules International conference

    Shinya Ariyasu, Zhiqi Cong, Osami Shoji, Yuichiro Aiba, Chie Kasai, Hiroki Onoda, Kazuto Suzuki, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Kamachi, Kazunari Yoshizawa, Yoshihito Watanabe

    43rd International Conference on Coordination Chemistry (ICCC2018)  2018.8.4 

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    Event date: 2018.7 - 2018.8

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Sendai International Center, Miyagi  

  14. Enzymatic Oxidation of Methane by Cytochrome P450BM3 Variants with Decoy Molecules under High Pressure Condition International conference

    Shinya Ariyasu, Zhiqi Cong, Osami Shoji, Yuichiro Aiba, Chie Kasai, Hiroki Onoda, Kazuto Suzuki, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Kamachi, Kazunari Yoshizawa, Yoshihito Watanabe

    Cytochrome P450 Biodiversity & Biotechnology 2018  2018.7.18 

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    Event date: 2018.7

    Language:English   Presentation type:Poster presentation  

    Venue:University of York   Country:United Kingdom  

  15. Catalytic Oxidation of Small Gaseous Alkanes by P450BM3 with Decoy Molecules International conference

    Shinya Ariyasu, Zhiqi Cong, Osami Shoji, Yuichiro Aiba, Chie Kasai, Hiroki Onoda, Kazuto Suzuki, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Kamachi, Kazunari Yoshizawa, Yoshihito Watanabe

    IRCCS The 1st International Symposium  2018.1.24 

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    Event date: 2018.1

    Language:English   Presentation type:Poster presentation  

    Venue:Kyusyu University  

  16. シトクロムP450 によるガス状アルカンの酸化 Invited

    有安 真也

    生物有機化学フォーラム2017  2017.11.11 

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    Event date: 2017.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京理科大学  

  17. Divalent Glycopeptide Antibiotic Analogs for Selective Inactivation and Two-Photon Imaging of Vancomycin-Resistant Bacteria over Non-Pathogenic Escherichia coli Invited International conference

    Shinya Ariyasu, Pei Chui Too, Jing Mu, Chi Ching Goh, Yichen Ding, Ya Lin Tnay, Edwin Kok Lee Yeow, Liang Yang, Lai Guan Ng, Shunsuke Chiba, Bengang Xing

    4th International Postgraduate Conference on Pharmaceutical Sciences 2016 (iPoPS2016)  2016.2.27 

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    Event date: 2016.2

    Language:English   Presentation type:Oral presentation (invited, special)  

  18. Evaluation of Radioprotective Activity of Zinc-Chelator Derivatives Invited International conference

    Shinya Ariyasu, Akiko Sawa, Misato Hoshi, Kengo Hanaya, Akinori Morita, Ippei Takahashi, Bing Wang, Shin Aoki

    International Symposium on Technologies against Cancer (ISTC2014)  2014.3.8 

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    Event date: 2014.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Edogawa, Japan  

  19. Antibody-Coated Phoreactive Microdevice for Selective Capture and Collection of Live Target Cells International conference

    Shinya Ariyasu, Yuto Mukai, Eita Watanabe, Toshihiro Suzuki, Kazutaka Horie, Masanori Hayase, Ryo Abe, Shin Aoki

    The 15th Asian Chemical Congress  2013.8.20 

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    Event date: 2013.8

    Language:English   Presentation type:Poster presentation  

    Venue:Singapore   Country:Singapore  

  20. Design and Synthesis of a Photocleavable Linker for the Isolation Device of Circulating Tumor Cells (CTCs) Invited International conference

    Shinya Ariyasu, Kengo Hanaya, Eita Watanabe, Toshihiro Suzuki, Megumi Tsunoda, Misato Hoshi, Masanori Kitamura, Masanori Hayase, Ryo Abe, Shin Aoki

    International Symposium on Technologies against Cancer (ISTC2011)  2011.9.2 

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Edogawa, Japan  

  21. Location of a gold cluster at the desired position of DNA via a zinc finger-metallothionein conjugate Invited International conference

    Shinya Ariyasu, Ryota Sakamoto, Takeshi Yamamura

    2nd International Symposium on Bioinorganic Chemistry of the New Era  2009.8.2 

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    Event date: 2009.7 - 2009.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Tateyama, Japan  

  22. ジンクフィンガー・メタロチオネイン融合蛋白質を用いた Au クラスターの DNA 上への配列 Invited

    有安 真也

    錯体化学若手の会関東支部勉強会  2007.12.1 

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    Event date: 2007.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京大学  

  23. Location of a gold cluster at the desired position of DNA via a zinc finger-metallothionein conjugate International conference

    Shinya Ariyasu, Ryota Sakamoto, Takeshi Yamamura

    International Union of Materials Research Societies-International Conference in Asia  2008.12 

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    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  24. Conjugation of Au11 Cluster with Cys-rich Peptides Containing the alpha-Domain of Metallothionein. International conference

    Shinya Ariyasu, Akira Onoda, Ryota Sakamoto, Takeshi Yamamura

    International Conference on Biological Inorganic Chemistry  2009.7 

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    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  25. Alignment of Gold Clusters on DNA via a Zinc Finger-Metallothionein Fusion Protein International conference

    Shinya Ariyasu, Takeshi Yamamura, Shin Aoki

    2010 International Chemical Congress of Pacific Basin Societies (PACICHEM2010)  2010.12 

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    Language:English   Presentation type:Poster presentation  

    Venue:Honolulu, Hawaii   Country:United States  

  26. The Selective Capture and Collection of Live Target Cells Using a Photoreactive Silicon Wafer Device Modified with Antibodies via Photocleavable Linkers

    Shinya Ariyasu, Kengo Hanaya, Eita Watanabe, Misato Hoshi, Toshihiro Suzuki, Kazutaka Horie, Masanori Hayase, Ryo Abe, Shin Aoki

    13th Tetrahedron Symposium Asia Edition  2012.11.27 

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    Language:English   Presentation type:Poster presentation  

    Venue:Taiwan   Country:Taiwan, Province of China  

  27. 光分解性リンカーを介した抗体修飾デバイスによる目的細胞の選択的捕捉と回収

    有安 真也、花屋 賢悟、渡邉 瑛太、星 美里、鈴木 利宙、堀江 和峰、早瀬 仁則、安部 良、青木 伸

    第6回バイオ関連化学シンポジウム  2012.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:北海道大学  

  28. 光分解性リンカーを用いた目的細胞の単離・回収用シリコンデバイスの開発

    有安 真也、花屋 賢悟、星 美里、渡邉 瑛太、鈴木 利宙、早瀬 仁則、安部 良、青木 伸

    日本薬学会第132年会  2012.3 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:北海道大学  

  29. 目的細胞の効率的検出・回収を目的とした光応答性抗体修飾シリコン基板の開発

    有安 真也、花屋 賢悟、星 美里、渡邉 瑛太、鈴木 利宙、早瀬 仁則、安部 良、青木 伸

    第5回バイオ関連化学シンポジウム  2011.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:茨城  

  30. 8-キノリノールスルホン酸エステルの光分解能向上のための官能基導入

    有安 真也、花屋 賢悟、角田 めぐみ、安部 良、青木 伸

    第60回有機合成化学協会関東支部シンポジウム  2011.5 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:千葉大学  

  31. ターゲット細胞の捕捉と回収を可能とする新規光応答性シリコン基板の開発

    有安 真也、花屋 賢悟、村上 明一、鈴木 利宙、渡邉 瑛太、東 隆親、安部 良、早瀬 仁則、青木 伸

    日本薬学会第131年会  2011.3 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:静岡大学  

  32. 8-メルカプトアデニンを配位子とする金クラスターの合成とチミンループ含有 DNA との結合

    有安 真也、角井 俊昭、坂本 良太、山村 剛士

    第58回錯体化学討論会  2009.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長崎大学  

  33. DNA-ジンクフィンガー相互作用を用いた金クラスターの自由配列

    有安 真也、角井 俊昭、坂本 良太、山村 剛士

    日本化学会第88春季年会  2008.3 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:立教大学  

  34. ジンクフィンガー-メタロチオネイン-Au ナノクラスター複合体の DNA 結合能の向上

    有安 真也、角井 俊昭、小野田 晃、坂本 良太、山村 剛士

    第57回錯体化学討論会  2007.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋工業大学  

  35. 温和な条件下での金ナノクラスターのメタロチオネインへの結合

    有安 真也、角井 俊昭、小野田 晃、山村 剛士

    日本化学会第87春季年会  2007.3 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:関西大学  

  36. ジンクフィンガーと Au ナノドット・クラスターの1:1複合体形成

    有安 真也、小野田 晃、山村 剛士

    第56回錯体化学討論会  2006.9 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島大学  

  37. Development of the Specific Antibodies-Coating Photoreactive Silicon Devices for Efficient Detection and Collection of Target Cell

    Shinya Ariyasu, Kengo Hanaya, Misato Hoshi, Eita Watanabe, Toshihiro Suzuki, Masanori Hayase, Ryo Abe, Shin Aoki

    8th AFMC International Medicinal and Chemical Symposium (AIMECS11)  2011 

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    Language:English   Presentation type:Oral presentation (general)  

    Venue:Tokyo  

  38. p53を標的とする放射線防護剤の探索と機構解析

    有安 真也、森田 明典、高橋 一平、澤 晶子、葛岡 朋代、内田 孝俊、大谷 聡一郎、細井 義夫、青木 伸

    日本化学会第93春季年会  2013.3.25 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:立命館大学  

  39. シトクロムP450によるガス状アルカンの高効率水酸化を目指した高圧反応装置の開発

    有安 真也、児玉 侑朔、笠井 千枝、愛場 雄一郎、渡辺 芳人、荘司 長三

    第52回酸化反応討論会  2019.11.10 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:奈良女子大学  

  40. Catalytic Oxidation of Methane by Cytochrome P450BM3 Variants with Decoy Molecules

    Shinya Ariyasu, Zhiqi Cong, Osami Shoji, Yuichiro Aiba, Chie Kasai, Hiroki Onoda, Kazuto Suzuki, Hiroshi Sugimoto, Yoshitsugu Shiro, Takashi Kamachi, Kazunari Yoshizawa, Yoshihito Watanabe

    2018.7.30 

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    Language:English   Presentation type:Oral presentation (general)  

  41. 高圧条件下におけるP450BM3の基質誤認識を用いたガス状アルカンの水酸化

    有安 真也、Zhiqi Cong, 荘司 長三、愛場 雄一郎、笠井 千枝、児玉 侑朔、小野田 浩宜、鈴木 和人、杉本 宏、城 宜嗣、渡辺 芳人

    第28回金属の関与する生体関連反応シンポジウム  2018.6.30 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東北大学  

  42. Hydroxylation of Small Gaseous Alkane by Mutated Cytochrome P450BM3 with Decoy Molecules

    Shinya Ariyasu, Osami Shoji, Yuichiro Aiba, Hiroshi Sugimoto, Yoshitsugu Shiro, Yoshihito Watanabe

    2018.3.20 

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    Language:English   Presentation type:Oral presentation (general)  

  43. 可視光応答性マイクロデバイスによる目的細胞の選択的捕捉と回収

    有安 真也・向井 裕人、竹田 礼紗、鈴木 利宙、早瀬 仁則、安部 良、青木 伸

    日本化学会第94春季年会  2014.3.27 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学  

  44. p53を標的とする放射線防護剤の設計と合成

    有安 真也・森田 明典・高橋 一平・王 冰・澤 晶子・星 美里・内田 孝俊・大谷 聡一郎・細井 義夫・青木 伸

    第7回バイオ関連化学シンポジウム  2013.9.27 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学  

  45. 光分解可能なケミカルリンカーの設計と合成と、目的細胞の選択的捕捉、回収用デバイスへの応用

    有安 真也、向井 裕人、渡邉 瑛太、鈴木 利宙、堀江 和峰、早瀬 仁則、安部 良、青木 伸

    第11回次世代を担う有機化学シンポジウム  2013.5.25 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:日本薬学会長井記念ホール  

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Research Project for Joint Research, Competitive Funding, etc. 1

  1. 基質認識型擬似基質を用いたシトクロムP450 による親水性化合物の位置、立体選択的水酸化技術の開発

    2020.7 - 2022.3

    2021年度天野エンザイム酵素研究助成 

    有安真也

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\600000 ( Direct Cost: \600000 )

KAKENHI (Grants-in-Aid for Scientific Research) 4

  1. Design of transition state of the enzyme catalyzing oxidation reactions by molecules that make the enzyme malfunction

    Grant number:22H05129  2022.6 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

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    Authorship:Coinvestigator(s) 

  2. シトクロムP450による擬似基質誘起1級炭素選択的水酸化反応の開発

    Grant number:21K05271  2021.4 - 2024.3

    科学研究費基金  基盤研究(C)

    有安真也

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

  3. Chemical redesign of biosynthetic system based on functional alteration of enzymes by synthetic molecules

    Grant number:19H04650  2019.4 - 2021.3

    Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3900000 ( Direct Cost: \3000000 、 Indirect Cost:\900000 )

  4. サイズ選択と光反応を利用した新規血中循環細胞回収チップの開発

    Grant number:23790023  2011.4 - 2013.3

    科学研究費補助金  若手研究(B)

    有安真也

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

 

Teaching Experience (On-campus) 12

  1. Chemistry Exercises II

    2023

  2. Chemistry Exercises I

    2023

  3. Laboratory Experiments in Inorganic Chemistry

    2023

  4. Chemistry Exercises II

    2022

  5. Chemistry Exercises I

    2022

  6. Laboratory Experiments in Inorganic Chemistry

    2022

  7. Chemistry Exercises II

    2021

  8. Chemistry Exercises I

    2021

  9. Chemistry Laboratory

    2021

  10. Laboratory Experiments in Inorganic Chemistry

    2021

  11. Laboratory Experiments in Inorganic Chemistry

    2020

  12. Chemistry Laboratory

    2020

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Social Contribution 2

  1. 名大 MIRAI グローバルサイエンスキャンパス 第2ステージ

    Role(s):Advisor

    2023.7 - 2023.8

  2. スーパーサイエンスハイスクール(SSH)事業「課題研究交流会」

    Role(s):Advisor

    2022.8

Academic Activities 3

  1. 日本化学会生体関連化学部会若手の会第34回サマースクール実行委員長

    Role(s):Planning, management, etc.

    2023.7

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    Type:Competition, symposium, etc. 

  2. 日本化学会生体機能関連化学部会若手幹事代表

    Role(s):Planning, management, etc.

    2022.3 - 2023.2

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    Type:Academic society, research group, etc. 

  3. 日本化学会生体機能関連化学部会若手会幹事

    Role(s):Planning, management, etc.

    2019.4

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    Type:Academic society, research group, etc.