2021/03/24 更新

写真a

イシカワ タクヤ
石川 卓哉
ISHIKAWA Takuya
所属
大学院医学系研究科 総合医学専攻 病態内科学 助教
大学院担当
大学院医学系研究科
学部担当
医学部 医学科
職名
助教

学位 2

  1. 医学博士 ( 2011年3月   名古屋大学 ) 

  2. 医学学士 ( 2001年3月   名古屋大学 ) 

研究分野 1

  1. ライフサイエンス / 消化器内科学  / 消化器内科学

現在の研究課題とSDGs 1

  1. 膵疾患に対する超音波内視鏡検査の診断能向上を目的とした人工知能の臨床応用

学歴 1

  1. 名古屋大学   医学系研究科   消化器内科学

    2007年4月 - 2011年3月

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    国名: 日本国

 

論文 82

  1. Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    BMC GASTROENTEROLOGY   21 巻 ( 1 )   2021年2月

  2. Lewis score on capsule endoscopy can predict the prognosis in patients with small bowel lesions of Crohn's disease

    Nishikawa Takahiro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY     2020年12月

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  3. Risks and characteristics of pancreatic cancer and pancreatic relapse in autoimmune pancreatitis patients

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   35 巻 ( 12 ) 頁: 2281 - 2288   2020年12月

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  4. The microbiome can predict mucosal healing in small intestine in patients with Crohn's disease

    Hattori Shun, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Yamamoto Kenta, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    JOURNAL OF GASTROENTEROLOGY   55 巻 ( 12 ) 頁: 1138 - 1149   2020年12月

  5. Endoscopic Ultrasound Elastography as a Novel Diagnostic Method for the Assessment of Hardness and Depth of Invasion in Colorectal Neoplasms

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Suzuki Hiroto, Kuno Takeshi, Yamada Kentaro, Hasegawa Issei, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTION     2020年11月

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  6. Accuracy of carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography using double-balloon endoscopy

    Niwa Yoshiki, Nakamura Masanao, Kawashima Hiroki, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Ishikawa Takuya, Kakushima Naomi, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Ishigami Masatoshi, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   26 巻 ( 42 )   2020年11月

  7. Endoscopic Activity and Serum TNF-alpha Level at Baseline Are Associated With Clinical Response to Ustekinumab in Crohn's Disease Patients

    Murate Kentaro, Maeda Keiko, Nakamura Masanao, Sugiyama Daisuke, Wada Hirotaka, Yamamura Takeshi, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Miyahara Ryoji, Ishigami Masatoshi, Nishikawa Hiroyoshi, Fujishiro Mitsuhiro

    INFLAMMATORY BOWEL DISEASES   26 巻 ( 11 ) 頁: 1669 - 1681   2020年11月

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  8. Mutation analysis of gastrointestinal stromal tumors using RNA obtained via endoscopic ultrasound-guided fine-needle aspiration

    Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Hirooka Yoshiki, Ohmiya Naoki, Fujishiro Mitsuhiro

    TRANSLATIONAL ONCOLOGY   13 巻 ( 11 )   2020年11月

  9. What is the role of measuring shear wave dispersion using shear wave elastography in pancreatic parenchyma?

    Suzuki Hirotaka, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Hashimoto Senju, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    JOURNAL OF MEDICAL ULTRASONICS   47 巻 ( 4 ) 頁: 575 - 581   2020年10月

  10. Diagnostic performance of endoscopic ultrasonography-guided elastography for solid pancreatic lesions: Shear-wave measurements versus strain elastography with histogram analysis

    Ohno Eizaburo, Kawashima Hiroki, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY     2020年9月

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  11. A forward-viewing radial-array echoendoscope is useful for diagnosing the depth of colorectal neoplasia invasion

    Kuno Takeshi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Esaki Masaya, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES     2020年9月

  12. Endoscopic removal of a fish bone piercing the bile duct after pancreaticoduodenectomy

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nakamura Masanao, Yamada Suguru, Hayashi Masamichi, Fujishiro Mitsuhiro

    ENDOSCOPY     2020年8月

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  13. Subjective Symptoms in Patients with Eosinophilic Esophagitis Are Related to Esophageal Wall Thickness and Esophageal Body Pressure

    Muroi Koichi, Kakushima Naomi, Furukawa Kazuhiro, Ishikawa Eri, Sawada Tsunaki, Ishikawa Takuya, Maeda Keiko, Yamamura Takeshi, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Funasaka Kohei, Miyahara Ryoji, Fujishiro Mitsuhiro

    DIGESTIVE DISEASES AND SCIENCES     2020年8月

  14. Can contrast-enhanced harmonic endoscopic ultrasonography accurately diagnose main pancreatic duct involvement in intraductal papillary mucinous neoplasms?

    Ohno Eizaburo, Kawashima Hiroki, Ishikawa Takuya, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    PANCREATOLOGY   20 巻 ( 5 ) 頁: 887 - 894   2020年7月

  15. Gender difference in the transabdominal ultrasound findings of solid-pseudopapillary neoplasm

    Sasaki Yutaka, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Shimoyama Yoshie, Ishikawa Eri, Fujishiro Mitsuhiro

    PANCREATOLOGY   20 巻 ( 5 ) 頁: 997 - 1003   2020年7月

  16. Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett's esophageal adenocarcinoma

    Hosono Isao, Miyahara Ryoji, Furukawa Kazuhiro, Funasaka Kohei, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Yokoi Takio, Hirooka Yoshiki, Fujishiro Mitsuhiro, Tsukamoto Tetsuya

    BMC GASTROENTEROLOGY   20 巻 ( 1 )   2020年6月

  17. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Sawada Tsunaki, Keiko Maeda, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   91 巻 ( 6 ) 頁: AB618 - AB618   2020年6月

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  18. PROSPECTIVE MULTICENTER STUDY ON THE USEFULNESS OF EUS-GUIDED FINE NEEDLE BIOPSY FOR THE DIAGNOSIS OF AUTOIMMUNE PANCREATITIS USING A 22-GAUGE FRANSEEN NEEDLE

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Keiko Maeda, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   91 巻 ( 6 ) 頁: AB172 - AB172   2020年6月

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  19. NOVEL METHOD TO DETERMINE THE DEPTH OF INVASION IN COLORECTAL NEOPLASMS WITH ULTRASOUND ELASTOGRAPHY USING A FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Kentaro, Hasegawa Issei, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   91 巻 ( 6 ) 頁: AB430 - AB430   2020年6月

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  20. EVALUATION OF RESECTABILITY BETWEEN ENDOSCOPIC TREATMENT METHODS FOR RECTAL NEUROENDOCRINE TUMOR

    Toriyama Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   91 巻 ( 6 ) 頁: AB101 - AB101   2020年6月

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  21. Clinical Factors Associated with Missing Colorectal Polyp on Colon Capsule Endoscopy

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Hirooka Yoshiki

    DIGESTION   101 巻 ( 3 ) 頁: 316 - 322   2020年5月

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  22. Double-balloon endoscopic retrograde cholangiopancreatography for patients who underwent liver operation: A retrospective study

    Nishio Ryo, Kawashima Hiroki, Nakamura Masanao, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Tanaka Hiroyuki, Sakai Daisuke, Miyahara Ryoji, Ishigami Masatoshi, Hirooka Yoshiki, Fujishiro Mitsuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   26 巻 ( 10 ) 頁: 1056 - 1066   2020年3月

  23. Usefulness of Endoscopic Ultrasound Elastography Combined With the Strain Ratio in the Estimation of Treatment Effect in Autoimmune Pancreatitis

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Maeda Keiko, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Fujishiro Mitsuhiro

    PANCREAS   49 巻 ( 2 ) 頁: E21 - E22   2020年2月

  24. Color information from linked color imaging is associated with invasion depth and vascular diameter in superficial esophageal squamous cell carcinoma

    Kobayashi Kenichi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Nakaguro Masato, Okumura Yuki, Hirooka Yoshiki, Fujishiro Mitsuhiro

    DIGESTIVE ENDOSCOPY   32 巻 ( 1 ) 頁: 65 - 73   2020年1月

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  25. Generation of magnifying endoscopic images of gastric neoplasms based on an all-in-focus algorithm

    Matsui Kenichi, Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Ohara Kenichi, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   35 巻 ( 1 ) 頁: 65 - 70   2020年1月

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  26. A Prospective Study of Factors Associated with Abdominal Pain in Patients during Unsedated Colonoscopy Using a Magnifying Endoscope

    Suzuki Hiroto, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Honda Takashi, Kawashima Hiroki, Ishigami Masatoshi, Fujishiro Mitsuhiro

    INTERNAL MEDICINE   59 巻 ( 15 ) 頁: 1795 - 1801   2020年

  27. Feasibility and usefulness of endoscopic ultrasonography-guided shear-wave measurement for assessment of autoimmune pancreatitis activity: a prospective exploratory study

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Ishizu Yoji, Kuzuya Teiji, Nakamura Masanao, Honda Takashi

    JOURNAL OF MEDICAL ULTRASONICS   46 巻 ( 4 ) 頁: 425 - 433   2019年10月

  28. Mucinous cystic neoplasm of the pancreas assessed with a real-time three-dimensional imaging using a transesophageal echocardiography probe

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Fujishiro Mitsuhiro

    CLINICAL JOURNAL OF GASTROENTEROLOGY   12 巻 ( 5 ) 頁: 479 - 483   2019年10月

  29. Objective evaluation of the therapeutic effect of ustekinumab on Crohn's disease

    Yamamura T., Nakamura M., Murate K., Maeda K., Sawada T., Mizutani Y., Nishikawa T., Hattori S., Yamamoto K., Pu L. Zorron Cheng Tao, Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   34 巻   頁: 145 - 145   2019年9月

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  30. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori S., Nakamura M., Yamamura T., Maeda K., Sawada T., Mizutani Y., Yamamoto K., Pu L. Zorron Cheng Tao, Honda T., Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   34 巻   頁: 152 - 152   2019年9月

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  31. CLINICAL SIGNIFICANCE OF THE PATENCY OF GASTROINTESTINAL TRACT IN CROHN'S DISEASE EVALUATED BY PATENCY CAPSULE

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Keisaku, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   89 巻 ( 6 ) 頁: AB333 - AB333   2019年6月

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  32. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji

    GASTROINTESTINAL ENDOSCOPY   89 巻 ( 6 ) 頁: AB608 - AB608   2019年6月

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  33. USEFULNESS OF THE FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE IN THE DIAGNOSIS OF INVASION DEPTH OF COLORECTAL NEOPLASIA

    Kuno Takeshi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Suzuki Hiroto, Esaki Masaya, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   89 巻 ( 6 ) 頁: AB324 - AB324   2019年6月

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  34. Utility of linked color imaging for endoscopic diagnosis of early gastric cancer

    Fujiyoshi Toshihisa, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Sawada Tsunaki, Maeda Keiko, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Nakaguro Masato, Nakatochi Masahiro, Hirooka Yoshiki

    WORLD JOURNAL OF GASTROENTEROLOGY   25 巻 ( 10 ) 頁: 1248 - 1258   2019年3月

  35. Comparison of 8-mm and 10-mm Diameter Fully-Covered Self-Expandable Metal Stents: A Multicenter Prospective Study in Patients with Distal Malignant Biliary Obstruction.

    Kawashima H, Hashimoto S, Ohno E, Ishikawa T, Morishima T, Matsubara H, Sugimoto H, Nonogaki K, Kanamori A, Hara K, Kuwahara T, Nakamura M, Miyahara R, Ishigami M, Ando M, Hirooka Y, Nagoya Biliary Stent Study (NABIS)-01 Group.

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society     2019年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/den.13366

    PubMed

  36. Transabdominal ultrasound elastography of the esophagogastric junction predicts reflux esophagitis

    Suhara Hiroki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF MEDICAL ULTRASONICS   46 巻 ( 1 ) 頁: 99 - 104   2019年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10396-018-0890-1

    Web of Science

    PubMed

  37. Randomized Phase II Study of Consecutive-Day versus Alternate-Day Treatment with S-1 as Second-Line Chemotherapy in Advanced Pancreatic Cancer

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Matsubara Hiroshi, Sasaki Yoji, Achiwa Koichi, Kanamori Akira, Sumi Hajime, Hirai Takanori, Nonogaki Koji, Tsuzuki Tomoyuki, Kuroiwa Masanori, Hattori Masashi, Maruta Shinya, Hiramatsu Takeshi, Ando Masahiko, Hashimoto Senju, Hirooka Yoshiki

    ONCOLOGY   96 巻 ( 1 ) 頁: 1-7   2019年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1159/000492388

    Web of Science

    PubMed

  38. Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained

    Hirose Takashi, Funasaka Kohei, Furukawa Kazuhiro, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki

    INTERNAL MEDICINE   58 巻 ( 6 ) 頁: 785 - 789   2019年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2169/internalmedicine.1628-18

    Web of Science

    PubMed

  39. Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji, Hashimoto Senju, Ishigami Masatoshi, Hirooka Yoshiki

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   2019 巻   2019年

  40. Feasibility of EUS-guided shear-wave measurement: A preliminary clinical study

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya

    ENDOSCOPIC ULTRASOUND   8 巻 ( 3 ) 頁: 215 - 216   2019年

  41. Lewis Score on Capsule Endoscopy as a Predictor of the Risk for Crohn's Disease-Related Emergency Hospitalization and Clinical Relapse in Patients with Small Bowel Crohn's Disease

    Nishikawa Takahiro, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki

    GASTROENTEROLOGY RESEARCH AND PRACTICE   2019 巻   2019年

  42. Validity of Capsule Endoscopy in Monitoring Therapeutic Interventions in Patients with Crohn's Disease

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Koulaouzidis Anastasios, Hirooka Yoshiki

    JOURNAL OF CLINICAL MEDICINE   7 巻 ( 10 )   2018年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/jcm7100311

    Web of Science

    PubMed

  43. Effectiveness of a modified 6-Fr endoscopic nasobiliary drainage catheter for patients with preoperative perihilar cholangiocarcinoma

    Kawashima Hiroki, Hirooka Yoshiki, Ohno Eizaburo, Ishikawa Takuya, Miyahara Ryoji, Watanabe Osamu, Hayashi Kazuhiko, Ishigami Masatoshi, Hashimoto Senju, Ebata Tomoki, Nagino Masato, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   6 巻 ( 8 ) 頁: E1020 - E1030   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1055/a-0614-2202

    Web of Science

    PubMed

  44. Objective evaluation of blood flow in the small-intestinal villous: quantification of findings from dynamic endoscopy with concomitant narrow-band imaging

    Takeyama Tomoaki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Ishigami Masatoshi, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   6 巻 ( 8 ) 頁: E941 - E949   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1055/a-0619-4965

    Web of Science

    PubMed

  45. Neuroendocrine neoplasm of pancreas with cystic degeneration mimicking mucinous cystic neoplasm

    Kaosombatwattana Uayporn, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Suhara Hiroki, Goto Hidemi

    CLINICAL JOURNAL OF GASTROENTEROLOGY   11 巻 ( 4 ) 頁: 333 - 337   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s12328-018-0846-4

    Web of Science

    PubMed

  46. Measurements of renal shear wave velocities in chronic kidney disease patients

    Sasaki Yutaka, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Takeshita Kyosuke, Goto Hidemi

    ACTA RADIOLOGICA   59 巻 ( 7 ) 頁: 884 - 890   2018年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1177/0284185117734417

    Web of Science

    PubMed

  47. International consensus statements on early chronic Pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with The International Association of Pancreatology, American Pancreatic Association, Japan Pancreas Society, PancreasFest Working Group and European Pancreatic Club

    Whitcomb David C., Shimosegawa Tooru, Chari Suresh T., Forsmark Christopher E., Frulloni Luca, Garg Pramod, Hegyi Peter, Hirooka Yoshiki, Irisawa Atsushi, Ishikawa Takuya, Isaji Shuiji, Lerch Markus M., Levy Philippe, Masamune Atsushi, Wilcox Charles M., Windsor John, Yadav Dhiraj, Sheel Andrea, Neoptolemos John P.

    PANCREATOLOGY   18 巻 ( 5 ) 頁: 516-527   2018年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.pan.2018.05.008

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  48. DIAGNOSTIC IMAGING SYSTEM WITH VIRTUAL ENTEROSCOPY AND COMPUTER-AIDED DETECTION FOR EVALUATION OF SMALL BOWEL LESIONS OF CROHN'S DISEASE

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Suhara Hiroki, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Oda Masahiro, Mori Kensaku, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB304-AB304   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  49. USEFULNESS OF HISTOLOGICAL ASSESSMENT WITH EUS-GUIDED FINE NEEDLE BIOPSY USING A NEW CORE NEEDLE IN PANCREATIC DISEASES

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Matsushita Masanobu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB432-AB433   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  50. USEFULLNESS OF CONTRAST-ENHANCED HARMONIC EUS(CH-EUS) FOR THE PREOPERATIVE ASSESSMENT OF MPD INVOLVEMENT IN IPMN; A RETROSPECTIVE COMPARISON STUDY OF CH-EUS AND IDUS

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Suhara Hiroki, Takeyama Tomoaki, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Matsushita Masanobu, Furukawa Kazuhiro, Yamamura Takeshi, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB426-AB427   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  51. THE DIAGNOSTIC ABILITY AND PITFALL OF JNET(JAPAN NBI EXPERT TEAM)CLASSIFICATION IN TRAINEES

    Suzuki Hiroto, Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Eri, Niwa Yoshiki, Uchida Genta, Otsuka Hiroyuki, Nishikawa Takahiro, Ishida Tetsuya, Yamada Keisaku, Hattori Shun, Kajikawa Go, Hashiguchi Hiroki, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB489-AB490   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  52. OUTCOMES AND PREDICTORS OF SEVERE SUBMUCOSAL FIBROSIS IN COLORECTAL ENDOSCOPIC SUBMUCOSAL DISSECTION

    Kaosombatwattana Uayporn, Yamamura Takeshi, Limsrivilai Julajak, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Leelakusolvong Somchai, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB377-AB377   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  53. EVALUATION OF LOCAL RECURRENCE AFTER COLD POLYPECTOMY COMPARED WITH CONVENTIONAL HOT POLYPECTOMY IN A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL

    Yamamura Takeshi, Saito Masashi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Suzuki Hiroto, Otsuka Hiroyuki, Uchida Genta, Nishikawa Takahiro, Ishida Tetsuya, Kuno Takeshi, Yamada Keisaku, Hattori Shun, Hashiguchi Hiroki, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB478-AB478   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  54. ENDOSCOPIC TREATMENT FOR SUPERFICIAL NON-AMPULLARY DUODENAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Suhara Hiroki, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   87 巻 ( 6 ) 頁: AB315-AB316   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  55. A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer

    Hirooka Yoshiki, Kasuya Hideki, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Villalobos Itzel B., Naoe Yoshinori, Ichinose Toru, Koyama Nobuto, Tanaka Maki, Kodera Yasuhiro, Goto Hidemi

    BMC CANCER   18 巻 ( 1 ) 頁: 596   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s12885-018-4453-z

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  56. Fecal calprotectin reflects endoscopic activity in patients with small-bowel Crohn's disease according to double-balloon endoscopy findings

    Matsuura Rinzaburo, Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Suhara Hiroki, Furukawa Kazuhiro, Ishikawa Takuya, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   80 巻 ( 2 ) 頁: 257 - 266   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.18999/nagjms.80.2.257

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  57. Nomogram-based prediction of rebleeding in small bowel bleeding patients: the 'PRSBB' score

    Uchida Genta, Hirooka Yoshiki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Suhara Hiroki, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi

    SCIENTIFIC REPORTS   8 巻 ( 1 ) 頁: 6378   2018年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/s41598-018-24868-0

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  58. Multiphase evaluation of contrast-enhanced endoscopic ultrasonography in the diagnosis of pancreatic solid lesions

    Ishikawa Takuya, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Hashizume Kiyotaka, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Goto Hidemi

    PANCREATOLOGY   18 巻 ( 3 ) 頁: 291 - 297   2018年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.pan.2018.02.002

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  59. Increase in breath hydrogen concentration was correlated with the main pancreatic duct stenosis.

    Sakai D, Hirooka Y, Kawashima H, Ohno E, Ishikawa T, Suhara H, Takeyama T, Koya T, Tanaka H, Iida T, Nishio R, Suzuki H, Uetsuki K, Matsushita M, Yamamura T, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Watanabe O, Ishigami M, Tsuruta A, Shin W, Goto H

    Journal of breath research   12 巻 ( 3 ) 頁: 036004   2018年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1088/1752-7163/aaaf77

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  60. Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis

    Kuwahara Takamichi, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   33 巻 ( 3 ) 頁: 756-761   2018年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jgh.13926

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  61. Clinical significance of gastrointestinal patency evaluation by using patency capsule in Crohn's disease

    Yoshimura Toru, Hirooka Yoshiki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   80 巻 ( 1 ) 頁: 121 - 128   2018年2月

  62. Comprehensive immunotherapy combined with intratumoral injection of zoledronate-pulsed dendritic cells, intravenous adoptive activated T lymphocyte and gemcitabine in unresectable locally advanced pancreatic carcinoma: a phase I/II trial

    Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kamigaki Takashi, Goto Shigenori, Takahara Masashi, Goto Hidemi

    ONCOTARGET   9 巻 ( 2 ) 頁: 2838-2847   2018年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.18632/oncotarget.22974

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  63. Natural history of pancreatic cystic lesions: A multicenter prospective observational study for evaluating the risk of pancreatic cancer

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Kanamori Akira, Ishikawa Hideki, Sasaki Yoji, Nonogaki Koji, Hara Kazuo, Hashimoto Senju, Matsubara Hiroshi, Hirai Takanori, Sumi Hajime, Sugimoto Hiroyuki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   33 巻 ( 1 ) 頁: 320-328   2018年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jgh.13967

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  64. Functional Correlation Between the Pancreas and the Small Intestine in Humans: The First Evaluation Using a Newly Developed Enteroscopy

    Hayashi Daijuro, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kuwahara Takamichi, Kawai Manabu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    PANCREAS   47 巻 ( 5 ) 頁: 601 - 608   2018年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MPA.0000000000001039

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  65. Diagnostic yield of small histological cores obtained with a new EUS-guided fine needle biopsy system

    Ishikawa Takuya, Mohamed Rachid, Heitman Steven J., Turbide Christian, Kumar Puja R., Goto Hidemi, Hirooka Yoshiki, Belletrutti Paul J.

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   31 巻 ( 12 ) 頁: 5143 - 5149   2017年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00464-017-5580-3

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  66. Development and validation of a new scoring system to determine the necessity of small-bowel endoscopy in obscure gastrointestinal bleeding

    Uchida Genta, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    DIGESTIVE AND LIVER DISEASE   49 巻 ( 11 ) 頁: 1218 - 1224   2017年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.dld.2017.08.036

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  67. In vivo histological diagnosis for gastric cancer using endocytoscopy

    Tsurudome Issei, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Nakaguro Masato, Satou Akira, Hirooka Yoshiki, Goto Hidemi

    WORLD JOURNAL OF GASTROENTEROLOGY   23 巻 ( 37 ) 頁: 6894 - 6901   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3748/wjg.v23.i37.6894

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  68. Making decision to treat with infliximab by the result of periodic surveillance with double-balloon endoscopy after ilectomy can obtain mucosal healing and avoid re-operation on patients with Crohn's disease for a long-term follow-up study

    Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Saito Masashi, Matsuura Rinzaburou, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Yamada Keishi, Kuno Takeshi, Hattori Shun, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   32 巻   頁: 287-287   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  69. ETV1 expression would be a predictive marker of malignancy in GIST

    Funasaka Kohei, Miyahara Ryoji, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   32 巻   頁: 79-80   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  70. Clinical factors related to false-positive rates of patency capsule examination

    Sawada Tsunaki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Elzaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY   10 巻 ( 8 ) 頁: 589 - 598   2017年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1177/1756283X17722744

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  71. Quantitative diagnosis of chronic pancreatitis using EUS elastography

    Kuwahara Takamichi, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Takeyama Tomoaki, Hashizume Kiyotaka, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Ishigami Masatoshi, Hashimoto Senju, Goto Hidemi

    JOURNAL OF GASTROENTEROLOGY   52 巻 ( 7 ) 頁: 868 - 874   2017年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00535-016-1296-8

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  72. Prospective multicenter phase II study of gemcitabine plus cisplatin in patients with unresectable gallbladder cancer

    Hirooka Yoshiki, Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nonogaki Koji, Kanamori Akira, Hirai Takanori, Uchida Hiroki, Shirai Osamu, Ishikawa Hideki, Goto Hidemi

    CANCER CHEMOTHERAPY AND PHARMACOLOGY   80 巻 ( 1 ) 頁: 119-125   2017年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00280-017-3341-6

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  73. Predicting the Depth of Invasion of Esophageal Squamous Cell Carcinoma: Under Experience of Linked Colored Imaging With LED Light Source

    Kobayashi Kenichi, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB527-AB527   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  74. Establishment of a New Scoring System for Predicting the Necessity of Double-Balloon Endoscopy in Obscure Gastrointestinal Bleeding

    Uchida Genta, Watanabe Osamu, Nakamura Masanao, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB300-AB300   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  75. The Study of Diagnostic Ability for the Colorectal Neoplasms by Imaged Enhanced Endoscopy Using by JNET (Japan NBI Expert Team) Classification

    Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Matsuura Rinzaburo, Saito Masashi, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB402-AB402   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  76. The Outcome of Treatment in Hypopharyngeal and Cervical Esophageal Carcinoma

    Fujiyoshi Toshihisa, Miyahara Ryoji, Funasaka Kohei, Furukawa Kazuhiro, Matsushita Masanobu, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Watanabe Osamu, Hirooka Yoshiki, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB597-AB598   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  77. One Year Follow-Up After Cold Polypectomy Compared With Hot Polypectomy for Small Colorectal Polyps - a Prospective Randomized Controlled Trial

    Saito Masashi, Yamamura Takeshi, Watanabe Osamu, Nakamura Masanao, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB365-AB366   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  78. Objective Assessment of Jejunal Villous Blood Flow for Evaluating Pancreas-Jejunum Functional Correlation Using a Novel Image Analyzing System

    Takeyama Tomoaki, Hirooka Yoshiki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Kawai Manabu, Suhara Hiroki, Hashizume Kiyotaka, Koya Toshinari, Tanaka Hiroyuki, Sakai Daisuke, Matsushita Masanobu, Yamamura Takeshi, Furukawa Kazuhiro, Funasaka Kohei, Nakamura Masanao, Miyahara Ryoji, Watanabe Osamu, Goto Hidemi

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB319-AB320   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  79. Novel EMR Technique for Preoperative Diagnosis and Treatment of Submucosal Tumor in the Small Bowel at Double-Balloon Endoscopy

    Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Sawada Tsunaki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB300-AB300   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  80. Clinical Factors Related to False Positive Rates of Patency Capsule Examination

    Sawada Tsunaki, Nakamura Masanao, Watanabe Osamu, Yamamura Takeshi, Matsushita Masanobu, Oshima Hiroshi, Sato Junichi, Saito Masashi, Matsuura Rinzaburo, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Uchida Genta, Otsuka Hiroyuki, Suzuki Hiroto, Nishikawa Takahiro, Ishida Tetsuya, Ishikawa Takuya, Furukawa Kazuhiro, Funasaka Kohei, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Goto Hidemi, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   85 巻 ( 5 ) 頁: AB305-AB305   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  81. Risk factors for rebleeding and risk-based follow-up of obscure gastrointestinal bleeding after its initial diagnosis.

    Uchida G, Nakamura M, Watanabe O, Yamamura T, Matsushita M, Ishikawa T, Furukawa K, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   114 巻 ( 10 ) 頁: 1819-1829   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.11405/nisshoshi.114.1819

    PubMed

  82. An Unusual Case of Pancreatic Metastasis from Squamous Cell Carcinoma of the Lung Diagnosed by EUS-Guided Fine Needle Biopsy

    Ishikawa Takuya, Hirooka Yoshiki, Teman Carolin J., Goto Hidemi, Belletrutti Paul J.

    CASE REPORTS IN GASTROINTESTINAL MEDICINE   2017 巻   頁: 3212056   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1155/2017/3212056

    Web of Science

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科研費 2

  1. 膵疾患に対する超音波内視鏡検査の診断能向上を目的とした人工知能の臨床応用

    研究課題/研究課題番号:20K12689  2020年4月 - 2023年3月

    石川 卓哉

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    担当区分:研究代表者 

    配分額:3510000円 ( 直接経費:2700000円 、 間接経費:810000円 )

    膵癌は早期発見が困難な上に進行が早く、極めて予後不良である。超音波内視鏡検査(EUS)は体の表面からの超音波検査と違って消化管の空気や脂肪などの影響を受けにくく、小さな膵癌の診断にも有用とされる。近年では超音波用造影剤を組みあわせることで血行動態などさらに詳細な評価も可能となった。しかし、EUSは検査の特性上主観性が高く、術者の技量や経験によるところが大きい。一方、消化器内視鏡画像を用いた人工知能(AI)診断の有用性が報告されており、EUSの分野でも応用が期待される。本研究では、EUSで得られた画像をAIに機械学習させることで術者の技量や経験の差を軽減し、膵癌診断における新たな診断体系の確立を目指す。

  2. 超音波内視鏡下エラストグラフィによる組織硬度測定による膵癌の臨床病理学的病態解析

    研究課題/研究課題番号:18K12054  2018年4月 - 2021年3月

    大野 栄三郎

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    担当区分:研究分担者 

    膵癌は豊富な線維性間質(がん関連線維芽細胞:cancer-associated fibroblast:CAF)を有し、「硬い」腫瘍と認識され、一方で癌細胞は硬い組織環境下において更に悪性度を増すとの報告も認め、膵癌およびその周囲組織の硬度と膵癌細胞の悪性度及び進行度に密接に関連している可能性がある。膵癌組織においてCAFは単なるbystanderではなく膵癌の進展など病態に強く関わっていることも報告されている。我々は臨床的に膵癌の硬度を測定し(超音波内視鏡下エラストグラフィ及び組織に対する原子間力顕微鏡(AFM))、硬度と膵癌の病理像(癌促進性、癌抑制性CAFの比率、分布)と臨床像(予後、化学療法の奏功率)との関連性を明らかにすることを目的としている。
    1)EUS-SWE(EUS-guided shear wave elastography)による膵癌を含む膵病変組織硬度測定
    超音波エラストグラフィは非侵襲的に組織弾性を測定し画像化、数値化する技術である。本年はEUS-SWEの膵癌をはじめとする膵病変の組織硬度測定精度の検証を行うため、もう一つの超音波エラストグラフィシステムであるStrain elastography法と対比して、硬度測定を行い(学会報告、論文報告JMU2019)、膵癌組織硬度測定における超音波エラストグラフィの使用方法に関する最適な測定条件を見いだす。
    2)膵癌、膵腫瘍患者の進行度と治療効果と組織硬度との関連性の検討
    EUS-SWE、超音波エラストグラフィにて得られた組織硬度は膵癌や自己免疫性膵炎(ステロイド治療前)にて他膵腫瘤性病変や正常膵に比して高硬度を示した。切除病理標本の免疫組織染色(AZAN,αSMA, CD31)による検討では、高硬度を示す膵癌においては膵癌組織中の線維芽細胞の比率が高い傾向を認めた。(未発表)
    EUS-SWを用いた膵癌、膵腫瘍測定における精度評価、問題点を抽出し、学会報告を行った。また現在論文投稿中である。硬度測定においてはStrain elastography法をヒストグラム解析にて半定量化する結果を用いることで診断精度の向上を認めた。
    現在、実際の膵癌の組織硬度測定結果と病理組織の免疫組織学的検討との対比を行うと同時に、組織硬度に関連するタンパク、CAFの発現を病理組織FFPE標本を用い検討する準備を行っている。臨床面においては膵癌組織硬度の差異をEUS-FNAによる針生検の病理組織所見との対比を行う前向き研究、膵癌化学療法前後における組織硬度変化の前向き研究を現在on goingにて進行中である。
    1)膵癌切除症例の病理組織所見と術前画像所見の対比:膵癌切除病理標本の間質組織の組成、成分解析を行うための免疫染色を行う。昨年度施行した免疫染色に加え、ミオシン軽鎖染色、Yap染色を追加する予定。さらに、線維芽細胞の組織硬度に関連すると考えられるlysyl oxidase(Lox)発現量を免疫染色にて評価を行う。(継続課題)
    2)膵癌組織硬度と発現遺伝子異常の相関の検討:膵癌組織を間質のCAFの発現、硬度により分類し、硬度の異なる膵癌組織における遺伝子異常の発現プロファイルを探索するため、EUS-FNAにて採取された膵癌検体もしくは切除例の病理組織標本よりlaser microdissection法にて癌組織を切り出し、癌組織よりDNAを抽出し、膵癌に代表的に認められる遺伝子変異をマイクロアレイにて解析し、硬度の異なる膵癌の遺伝子プロファイルの差異を検討する。(継続課題)
    3)物理的な膵癌をはじめとした臓器、組織の硬度測定法の開発を目指す。
    臓器の組織組成、物理学的な生体組織の特性を評価し、既存の診断機器、治療機器、デバイスの機能的特性を新たな研究領域として体系化する。具体的には細胞硬度、細胞集塊硬度、組織硬度、臓器硬度にスケール分類した場合、各スケールに併せた適切な硬度測定方法を確立する。当面、臨床的に最優先の課題としては生検にて採取された細胞集塊の硬度測定の定量化と実際の疾患、病態、既存の硬度測定(エラストデータ)との相関を示すベースとなるデータの集積を行う。
    1)2)に関しては既存の膵癌組織を用いた遺伝子プロファイル、タンパク発現解析を目的としたゲノム解析研究専門審査委員会の承認を得て研究を開始している。