The University of Tokyo   Institute of Molecular and Cellular Bioscience   post-doc

2002.6 - 2003.3

Wadsworth Center, New York State Department of Health   Division of Genetic Disorders   post-doc

2000.4 - 2002.5

Mouse retrotransposons: sequence structure, evolutionary age, genomic distribution and function Open Access

Kawase, M; Ichiyanagi, K

GENES & GENETIC SYSTEMS   Vol. 98 ( 6 ) page： 337 - 351   2023.11

Diversity and evolution of highly repetitive DNA sequences constituting chromosome-site specific heterochromatin in two Gerbillinae species

Uno, Y; Matsubara, K; Inoue, J; Inazawa, J; Shinohara, A; Koshimoto, C; Ichiyanagi, K; Matsuda, Y

CYTOGENETIC AND GENOME RESEARCH   Vol. 163 ( 1-2 ) page： 42 - 51   2023.11

C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia. Open Access

Kobayashi M, Kanbe F, Ishii R, Tsubouchi H, Hirai K, Miyasaka Y, Ohno T, Oda H, Ikeda S, Katoh H, Ichiyanagi K, Ishikawa A, Murai A, Horio F

Scientific reports   Vol. 13 ( 1 ) page： 13813   2023.8

Sequence Divergence and Retrotransposon Insertion Underlie Interspecific Epigenetic Differences in Primates Open Access

Hirata, M; Ichiyanagi, T; Katoh, H; Hashimoto, T; Suzuki, H; Nitta, H; Kawase, M; Nakai, R; Imamura, M; Ichiyanagi, K

MOLECULAR BIOLOGY AND EVOLUTION   Vol. 39 ( 10 )   2022.10

The Expression Dynamics of piRNAs Derived From Male Germline piRNA Clusters and Retrotransposons Open Access

Kawase, M; Ichiyanagi, K

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY   Vol. 10   page： 868746   2022.5

Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells Open Access

Fukuda, K; Makino, Y; Kaneko, S; Shimura, C; Okada, Y; Ichiyanagi, K; Shinkai, Y

ELIFE   Vol. 11   2022.3

The regulatory mechanisms that make mature sperm cells in the mouse Open Access

Ichiyanagi, K

GENES & GENETIC SYSTEMS   Vol. 97 ( 1 ) page： 1 - 1   2022.2

The fifth Japanese meeting on biological function and evolution through interactions between hosts and transposable elements Open Access

Ichiyanagi, K; Saito, K

MOBILE DNA   Vol. 13 ( 1 ) page： 3   2022.1

TFB2M and POLRMT are essential for mammalian mitochondrial DNA replication Open Access

Inatomi, T; Matsuda, S; Ishiuchi, T; Do, Y; Nakayama, M; Abe, S; Kasho, K; Wanrooij, S; Nakada, K; Ichiyanagi, K; Sasaki, H; Yasukawa, T; Kang, D

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH   Vol. 1869 ( 1 ) page： 119167   2022.1

Quantitative Separation of Precipitation and Permafrost Waters Used for Evapotranspiration in a Boreal Forest: A Numerical Study Using Tracer Model Open Access

Park, H; Tanoue, M; Sugimoto, A; Ichiyanagi, K; Iwahana, G; Hiyama, T

JOURNAL OF GEOPHYSICAL RESEARCH-BIOGEOSCIENCES   Vol. 126 ( 12 )   2021.12

melRNA-seq for Expression Analysis of SINE RNAs and Other Medium-Length Non-Coding RNAs Open Access

Mori, Y; Ichiyanagi, K

MOBILE DNA   Vol. 12 ( 1 ) page： 15   2021.6

B2 SINE Copies Serve as a Transposable Boundary of DNA Methylation and histone Modifications in the Mouse Open Access

Ichiyanagi, T; Katoh, H; Mori, Y; Hirafuku, K; Boyboy, BA; Kawase, M; Ichiyanagi, K

MOLECULAR BIOLOGY AND EVOLUTION   Vol. 38 ( 6 ) page： 2380 - 2395   2021.6

Dispersal history of <i>Miniopterus fuliginosus</i> bats and their associated viruses in east Asia Open Access

Kimprasit, T; Nunome, M; Iida, K; Murakami, Y; Wong, ML; Wu, CH; Kobayashi, R; Hengjan, Y; Takemae, H; Yonemitsu, K; Kuwata, R; Shimoda, H; Si, LF; Sohn, JH; Asakawa, S; Ichiyanagi, K; Maeda, K; Oh, HS; Mizutani, T; Kimura, J; Iida, A; Hondo, E

PLOS ONE   Vol. 16 ( 1 ) page： e0244006   2021.1

Combined deletions of <i>IHH</i> and <i>NHEJ1</i> cause chondrodystrophy and embryonic lethality in the Creeper chicken Open Access

Kinoshita, K; Suzuki, T; Koike, M; Nishida, C; Koike, A; Nunome, M; Uemura, T; Ichiyanagi, K; Matsuda, Y

COMMUNICATIONS BIOLOGY   Vol. 3 ( 1 ) page： 144   2020.3

Non-transmissible MV Vector with Segmented RNA Genome Establishes Different Types of iPSCs from Hematopoietic Cells Open Access

Hiramoto, T; Tahara, M; Liao, JY; Soda, Y; Miura, Y; Kurita, R; Hamana, H; Inoue, K; Kohara, H; Miyamoto, S; Hijikata, Y; Okano, S; Yamaguchi, Y; Oda, Y; Ichiyanagi, K; Toh, H; Sasaki, H; Kishi, H; Ryo, A; Muraguchi, A; Takeda, M; Tani, K

MOLECULAR THERAPY   Vol. 28 ( 1 ) page： 129 - 141   2020.1

Characterization of genetic-origin-dependent monoallelic expression in mouse embryonic stem cells Open Access

Ohishi, H; Yeung, WKA; Unoki, M; Ichiyanagi, K; Fukuda, K; Maenohara, S; Shirane, K; Chiba, H; Sado, T; Sasaki, H

GENES TO CELLS   Vol. 25 ( 1 ) page： 54 - 64   2020.1

Selective Reduction Mechanism of Graphene Oxide Driven by the Photon Mode <i>versus</i> the Thermal Mode

Hada, M; Miyata, K; Ohmura, S; Arashida, Y; Ichiyanagi, K; Katayama, I; Suzuki, T; Chen, W; Mizote, S; Sawa, T; Yokoya, T; Seki, T; Matsuo, J; Tokunaga, T; Itoh, C; Tsuruta, K; Fukaya, R; Nozawa, S; Adachi, S; Takeda, J; Onda, K; Koshihara, S; Hayashi, Y; Nishina, Y

ACS NANO   Vol. 13 ( 9 ) page： 10103 - 10112   2019.9

Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring Open Access

Inoguchi, Y; Ichiyanagi, K; Ohishi, H; Maeda, Y; Sonoda, N; Ogawa, Y; Inoguchi, T; Sasaki, H

SCIENTIFIC REPORTS   Vol. 9 ( 1 ) page： 10181   2019.7

Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders.

Wakisaka KT, Tanaka R, Hirashima T, Muraoka Y, Azuma Y, Yoshida H, Tokuda T, Asada S, Suda K, Ichiyanagi K, Ohno S, Itoh M, Yamaguchi M

Brain research   Vol. 1708   page： 207 - 219   2019.4

TE studies in Japan: the fourth Japanese meeting on host-transposon interactions Open Access

Ichiyanagi, K; Saito, K

MOBILE DNA   Vol. 10   page： 11   2019.3

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA Open Access

Matsuda Shigeru, Yasukawa Takehiro, Sakaguchi Yuriko, Ichiyanagi Kenji, Unoki Motoko, Gotoh Kazuhito, Fukuda Kei, Sasaki Hiroyuki, Suzuki Tsutomu, Kang Dongchon

SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page： 5801   2018.4

Combined Loss of JMJD1A and JMJD1B Reveals Critical Roles for H3K9 Demethylation in the Maintenance of Embryonic Stem Cells and Early Embryogenesis Open Access

Kuroki Shunsuke, Nakai Yuji, Maeda Ryo, Okashita Naoki, Akiyoshi Mika, Yamaguchi Yutaro, Kitano Satsuki, Miyachi Hitoshi, Nakato Ryuichiro, Ichiyanagi Kenji, Shirahige Katsuhiko, Kimura Hiroshi, Shinkai Yoichi, Tachibana Makoto

STEM CELL REPORTS   Vol. 10 ( 4 ) page： 1340 - 1354   2018.4

Association of zygotic piRNAs derived from paternal P elements with hybrid dysgenesis in Drosophila melanogaster Open Access

Wakisaka Keiko Tsuji, Ichiyanagi Kenji, Ohno Seiko, Itoh Masanobu

MOBILE DNA   Vol. 9   page： 7   2018.2

Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites Open Access

Shimosuga Ken-ichi, Fukuda Kei, Sasaki Hiroyuki, Ichiyanagi Kenji

MOBILE DNA   Vol. 8   page： 20   2017.12

Locus-specific hypomethylation of the mouse IAP retrotransposon is associated with transcription factor-binding sites. Reviewed Open Access

Shimosuga KI, Fukuda K, Sasaki H, Ichiyanagi K.

MOBILE DNA   Vol. 8   page： 20   2017.12

Diversity of P-element piRNA production among M' and Q strains and its association with P-M hybrid dysgenesis in Drosophila melanogaster. Reviewed Open Access

Wakisaka KT, Ichiyanagi K, Ohno S, Itoh M

MOBILE DNA   Vol. 8   page： 13   2017.10

Diversity of <i>P-</i>element piRNA production among M' and Q strains and its association with P-M hybrid dysgenesis in <i>Drosophila melanogaster</i> Open Access

Wakisaka, KT; Ichiyanagi, K; Ohno, S; Itoh, M

MOBILE DNA   Vol. 8   page： 13   2017.10

Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability. Reviewed Open Access

Fukuda K., Inoguchi Y., Ichiyanagi K., Ichiyanagi T., Go Y., Nagano M., Yanagawa Y., Takaesu N., Ohkawa Y., Imai H., and Sasaki H.

Hum Mol Genet   Vol. 26 ( 18 ) page： 3508 - 3519   2017.9

Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice. Reviewed Open Access

Inoue K., Ichiyanagi K., Fukuda K., Glinka M., and Sasaki H.

PLoS Genet   Vol. 13 ( 7 ) page： e1006926   2017.7

The genetic diversity of D-loop sequences in eastern bent-winged bats (Miniopterus fuliginosus) living in Wakayama Prefecture, Japan. Reviewed Open Access

Iida K., Kobayashi R., Hengjan Y., Nagata N., Yonemitsu K., Nunome M., Kuwata R., Suzuki K., Ichiyanagi K., Maeda K., OhmoriY., and Hondo E.

J Vet Med Sci   Vol. 79 ( 6 ) page： 1142 - 1145   2017.6

Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency. Reviewed Open Access

  Vol. 102 ( 3 ) page： 454 - 465   2017.3

Software updates in the Illumina HiSeq platform affect whole-genome bisulfite sequencing. Reviewed Open Access

Toh H., Shirane K., Miura F., Kubo N. Ichiyanagi K., Hayashi K., Saitou M., Suyama M., Ito T., and Sasaki H

BMC Genomics   Vol. 18 ( 1 ) page： 31   2017.1

Chd5 regulates MuERV-L/MERVL expression in mouse embryonic stem cells via H3K27me3 modification and histone H3.1/H3.2. Reviewed

  Vol. 117   page： 780-792   2016

TE studies in Japan: The third Japanese meeting on host-transposon interactions. Open Access

  Vol. 7   2016

Regulating Pol III transcription to change Pol II transcriptome. Invited Open Access

  Vol. 13   page： 3625-3626   2014

HSP90α plays an important role in piRNA biogenesis and retrotransposon repression in mouse. Reviewed Open Access

Ichiyanagi T., Ichiyanagi K., Ogawa A., Kuramochi-Miyagawa S., Nakano T., Chuma S., Sasaki H., and Udono H.

Nucleic Acids Res   Vol. 42   page： 11903-11911   2014

Transposable elements in eukaryotic genomes: epigenetic regulation by the host and functionalization for the host. Reviewed

Ichiyanagi K.

Genes Genet Syst   Vol. 88   page： 1   2013

Three novel ZBTB24 mutations identified in Japanese and Cape Verdean type 2 ICF syndrome patients. Reviewed Open Access

Nitta H., Unoki M., Ichiyanagi K., Kosho T., Shigemura T., Takahashi H., Velasco G., Francastel C., Picard C., Kubota T., and Sasaki H.

J Hum Genet   ( 58 ) page： 455-460   2013

Targeted gene silencing in mouse germ cells by insertion of a homologous DNA into a piRNA generating locus. Reviewed Open Access

Yamamoto Y., Watanabe T., Hoki Y., Shirane K., Li Y., Ichiyanagi K., Kuramochi- Miyagawa S., Toyoda A., Fujiyama A., Oginuma M., Suzuki H., Sado T., Nakano T., and Sasaki, H.

Genome Res   Vol. 23   page： 292-299   2013

Identification of both copy number variation-type and constant-type core elements in a large segmental duplication region of the mouse genome. Reviewed Open Access

Umemori J., Mori A., Ichiyanagi K., Uno T., and Koide T.

BMC Genomics   Vol. 14   page： 455   2013

DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes. Reviewed

Fukuda K., Ichiyanagi K.*, Yamada Y., Go Y., Udono T., Wada S., Maeda M., Soejima H., Saitou N., Ito T., and Sasaki H.

J Hum Genet   Vol. 58   page： 446-454   2013

Accumulation and loss of non-CpG methylation during male germ-cell development. Reviewed

Ichiyanagi T., Ichiyanagi K., Miyake M., and Sasaki H.

Nucleic Acids Res   Vol. 41   page： 738-745   2013

Epigenetic regulation of transcription and possible functions of mammalian short interspersed elements, SINEs. Reviewed Open Access

  Vol. 88   page： 19-29   2013

Inhibition of MspI cleavage activity by hydroxymethylation of the CpG site: A concern for DNA modification studies using restriction endonucleases. Reviewed

Ichiyanagi K.

Epigenetics   Vol. 7   page： 131-136   2012

Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development. Reviewed Open Access

Ichiyanagi K.*, Li Y., Watanabe T., Ichiyanagi T., Fukuda K., Kitayama J., Yamamoto Y., Kuramochi-Miyagawa S., Nakano T., Yabuta Y., Seki Y., Saitou M., and Sasaki H.

Genome Res   Vol. 21   page： 2058-2066   2011

Role for piRNAs and non-coding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Reviewed

Watanabe T., Tomizawa S., Mitsuya K., Totoki Y., Yamamoto Y., Kuramochi-Miyagawa S., Iida N., Hoki Y., Murphy P.J., Toyoda A., Gotoh K., Hiura H., Arima T., Fujiyama A., Sado T., Shibata T., Nakano T., Lin H., Ichiyanagi K., Soloway P. D., and Sasaki H.

Science   Vol. 332   page： 848-852   2011

Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse

Kenji Ichiyanagi, Beverly Ann Boyboy

2024.9.4 

ヒトAlu SINEの発現制御機構

一柳健司

第17回日本エピジェネティクス研究会  2024.6.13  日本エピジェネティクス研究会

ヒトAlu SINEの発現制御機構 Invited

一柳健司

第46回日本分子生物学会  2023.12.7  日本分子生物学会

melRNA-seqを用いた ヒトAlu SINEの発現解析

一柳健司、近藤咲良、北村颯太

第95回日本遺伝学会  2023.9.6  日本遺伝学会

マウス生殖細胞発生過程におけるエピジェネティック制御 　〜レトロトランスポゾンの視点から Invited International coauthorship

一柳健司

第16回日本エピジェネティクス研究会  2023.6.20  日本エピジェネティクス研究会

霊長類におけるエピゲノム進化過程の解明に向けて Invited

一柳健司

第76回日本人類学会大会・第38回日本霊長類学会大会連合大会  2022.9.18  日本人類学会、日本霊長類学会

ヒトとチンパンジーiPS細胞間のエピジェネティック差のゲノム要因

平田真由 、一柳朋子、加藤大和、橋本琢磨、新田洋久、仲井理沙子、今村公紀、一柳健司

第94回遺伝学会大会  2022.9.15  日本遺伝学会

哺乳類におけるレトロトランスポゾンのエピジェネティック制御機構 Invited

一柳健司

環境エピゲノミクス研究会  2022.6.18  環境エピゲノミクス研究会

ヒトとチンパンジーの iPS細胞のエピゲノム比較解析 Invited

一柳健司

第50回ホミニゼーション研究会  2022.3.22 

マウスB2 SINEはDNAメチル化とヒストン修飾の「動くバウンダリー」として機能する Invited

一柳健司

第44回日本分子生物学会  2021.12.2 

ローカスレベルでのSINE RNA発現解析を 可能にするmelRNA-seq法

一柳健司

第93回日本遺伝学会大会 

SINE配列によるクロマチン区画化 Invited

一柳健司

第5回トランスポゾン研究会  2021.8.27 

B2 SINE copies serve as a transposable boundary of DNA methylation and histone modifications in the mouse Invited International conference

Kenji Ichiyanagi

FASEB meeting on mobile DNA  2021.6.9 

霊長類iPS細胞を用いたエピゲノム進化の解析

一柳健司

第21回日本再生医療学会  2021.3.17 

Paternal Transgenerational Epigenetic Inheritance of Diabetes in Mice

Beverly Ann G. Boyboy, Tomoko Ichiyanagi, Hirohisa Nitta, Kenji Ichiyanagi

2020.12.2 

マウス雄性生殖細胞発生過程におけるレトロトランスポゾンのエピジェネティッ ク制御機構

一柳健司 、杉本大空 、川瀬雅貴

第92回日本遺伝学会年会  2020.9.16 

マウス精母細胞におけるSETDB1による遺伝子トレトロトランスポゾンの転写抑制機構

川瀬雅貴、杉本大空、一柳健司

第92回日本遺伝学会大会 

生活習慣病による生殖細胞のエピジェネティック変化およびゲノム変異の発生機序

2017.10 - 2021.9

生殖細胞形成におけるレトロトランスポゾン制御ネットワークの解明

2013.4 - 2014.3

マウス雄性生殖細胞形成過程におけるSINEレトロトランスポゾンのDNAメチル化ダイナミクス

2009.4 - 2010.4

Development of a method for medium-length RNA, and functional analysis of SINE non-coding RNAs

Grant number：16K14784  2016.4 - 2019.3

Ichiyanagi Kenji

Epigenetic regulatory network for retrotransposon silencing during germ cell development

Grant number：16H04817  2016.4 - 2019.3

Ichiyanagi Kenji

Dynamics and regulation of genomic imprinting and DNA methylation

Grant number：25112010  2013.6 - 2018.3

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Sasaki Hiroyuki

エピジェネティック修飾と分子シャペロンによるレトロトランスポゾンの制御機構

Grant number：25503003  2013.4 - 2016.3

科学研究費補助金  基盤研究(C)

マウス生殖細胞形成におけるSINE配列のDNAメチル化ダイナミクスと機能制御

Grant number：22770009  2010.4 - 2012.3

科学研究費補助金  若手研究(B)

マウスにおけるエピゲノム種内多型の同定および遺伝的多型や表現型多様性との関係性

Grant number：21200037  2009.4 - 2012.3

科学研究費補助金  新学術領域研究

ゲノム中に大量に散在するレトロトラスポゾン配列のゲノム機能における役割

Grant number：19770002  2007.3 - 2009.3

科学研究費補助金  若手研究(B)

遺伝学

2020

生物情報処理演習

2018

動物遺伝学特論

2018

分子細胞生物学１

2018

遺伝学

2018

生物学基礎II

2018

分子生物学基礎II

2017

動物遺伝・生理学特論

2016

遺伝学

2016