
Strong education professional with a Doctor of Philosophy (PhD) focused in Pediatric Oncology from Nagoya University
Updated on 2023/04/18
PhD ( 2010.3 名古屋大学 )
MD degree ( 2002.1 Medical degree )
Life Science / Tumor biology
Life Science / Hematology and medical oncology
Life Science / Immunology / 膵癌
PD-L1を標的としたウイルス表面リガンド改変腫瘍溶解性ウイルスの開発
AMEE: Association for Medical Education in Europe Membershio
2020.3 - 2023.3
Committee type:Academic society
Relapse of leukemia with loss of mismatched HLA due to uniparental disomy following haploidentical hematopoietic stem cell transplantation Invited Reviewed
Itzel Bustos Villalobos, Y. Takahashi, Y. Akatsuka, H. Muramatsu, N. Nishio, A.Hama, H. Yagasaki, H. Saji, M. Kato, S. Ogawa and S. Kojima
Blood Vol. 115 ( 15 ) page: 3158 - 3161 2010
S-1 facilitates canerpaturev (C-REV)-induced antitumor efficacy in a triple-negative breast cancer model
Miyajima Noriyuki, Eissa Ibrahim Ragab, Abdelmoneim Mohamed, Naoe Yoshinori, Ichinose Toru, Matsumura Shigeru, Bustos-Villalobos Itzel, Mukoyama Nobuaki, Morimoto Daishi, Shibata Masahiro, Takeuchi Dai, Tsunoda Nobuyuki, Kikumori Toyone, Tanaka Maki, Kodera Yasuhiro, Kasuya Hideki
NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 83 ( 4 ) page: 683 - 696 2021.11
Oncolytic herpes simplex virus HF10 (canerpaturev) promotes accumulation of CD8(+)PD-1(-) tumor-infiltrating T cells in PD-L1-enriched tumor microenvironment
Eissa Ibrahim Ragab, Mukoyama Nobuaki, Abdelmoneim Mohamed, Naoe Yoshinori, Matsumura Shigeru, Bustos-Villalobos Itzel, Ichinose Toru, Miyajima Noriyuki, Morimoto Daishi, Tanaka Maki, Fujimoto Yasushi, Sone Michihiko, Kodera Yasuhiro, Kasuya Hideki
INTERNATIONAL JOURNAL OF CANCER Vol. 149 ( 1 ) page: 214 - 227 2021.7
C-REV Retains High Infectivity Regardless of the Expression Levels of cGAS and STING in Cultured Pancreatic Cancer Cells
Morimoto Daishi, Matsumura Shigeru, Bustos-Villalobos Itzel, Sibal Patricia Angela, Ichinose Toru, Naoe Yoshinori, Eissa Ibrahim Ragab, Abdelmoneim Mohamed, Mukoyama Nobuaki, Miyajima Noriyuki, Tanaka Maki, Kodera Yasuhiro, Kasuya Hideki
CELLS Vol. 10 ( 6 ) 2021.6
Problem-Based Learning in Child and Adolescent Psychiatry: A Perspective from Japan
Iwatsuki Junko, Kondo Takeshi, Takahashi Noriyuki, Takami Hideki, Nishigori Hiroshi, Bustos-Villalobos Itzel, Aleksic Branko, Kasuya Hideki, Ban Nobutaro, Yagi Tetsuya, Skokauskas Norbert
ADVANCES IN MEDICAL EDUCATION AND PRACTICE Vol. 12 page: 1329 - 1335 2021
Combination of Cetuximab and Oncolytic Virus Canerpturev synergistically inhibits Human colorectal cancer Growth Invited Reviewed
Wu Z, Ichinose T, Naoe Y, Matsumura S, Villalobos IB, Eissa IR, Miyajima N, Kasuya H
Mol Ther Oncolytics 2019.5
Joint degree program for graduate students at the Nagoya University Graduate school of medicine Invited Reviewed
Kasuya H, Aleksic B, Sumigama S, Bustos I, Hasegawa H, Kasai MP, Kobayashi M, Samizo Y
Nagoya J Med Sci 2019.5
The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers
Eissa Ibrahim Ragab, Bustos-Villalobos Itzel, Ichinose Toru, Matsumura Shigeru, Naoe Yoshinori, Miyajima Noriyuki, Morimoto Daishi, Mukoyama Nobuaki, Wu Zhiwen, Tanaka Maki, Hasegawa Hitoki, Sumigama Seiji, Aleksic Branko, Kodera Yasuhiro, Kasuya Hideki
CANCERS Vol. 10 ( 10 ) 2018.10
The current status and future prospect of oncolytic viruses in clinical trials against Melanoma, Glioma, Pancreatic, and Breast cancers Invited Reviewed International coauthorship
Eissa IR, Bustos-Villalobos I, Ichinose T, Matsumura S, Naoe Y, Miyajima N, Morimoto D, Mukoyama N, Tanaka M, Hasegawa H, Sumigama A, Aleksic B, Kodera Y, Kasuya H
Cancers Vol. 10 ( 10 ) 2018.9
A Phase I clinical trial od EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer Invited Reviewed International coauthorship
Hirooka Y, Kasuya H, Ishikawa T, Kawashima H, Ohno E, Villalobos IB, Naoe Y, Ichinose T, Koyama N, Tanaka M, Kodera Y, Goto H
BMC Cancer Vol. 18 ( 1 ) page: 596 2018.5
ITK inhibition for the targeted treatment of CTCL.
Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A, Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis E
Journal of dermatological science Vol. 87 ( 1 ) page: 88 - 91 2017.7
Pathophysiology of autoimmune bullous diseases: Nature versus nurture Invited Reviewed
Forum Patel, Reason Wilken, Falin B Patel, Hawa Sultani, Itzel Bustos, Christopher Duong, John J Zone, Siba P Raychaudhuri, Emanual Maverakis
Indian Journal of Dermatology Vol. 62 ( 3 ) page: 262 - 267 2017.5
Curative effect of HF10 on liver and peritoneal metastasis mediated by host immunity Invited Reviewed
12) Hotta Y, Kasuya H, Bustos Villalobos Itzel, Naoe Y, Ichinose T, Tanaka M, Kodera Y
Oncolytic Virotherapy Vol. 6 page: 31 - 38 2017.3
CD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity Invited Reviewed
Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E
Journal of Autoimmunity Vol. 77 page: 76 - 88 2017.2
Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials.
Eissa IR, Naoe Y, Bustos-Villalobos I, Ichinose T, Tanaka M, Zhiwen W, Mukoyama N, Morimoto T, Miyajima N, Hitoki H, Sumigama S, Aleksic B, Kodera Y, Kasuya H
Frontiers in oncology Vol. 7 page: 149 2017
Serbian Language version of the Modified Checklist for Autism in Toddlers, revised, with Follow-up: Cross-Cultural Adaptation and Assessment of Reliability Invited Reviewed
Carakovac Mia, Jovanovic Jelena, Kalanj Marko, Rudic Nenad, Aleksic-Hil Olivera, Aleksic Branko, Villalobos Bustos Itzel, Kasuya Hideki, Ozaki Norio, Lecic-Tosevski Dusica, Pejovic-Milovancevic Milica
Scientific report Vol. 6 page: 38222 2016.12
Persistence of Autoreactive IgA-Secreting B cells Despite Multiple Immunosuppressive Medications Including Rituximab (Anti-CD20 therapy): A Mechanism For Treatment-Resistant IgA Immunobullous Diseases Invited Reviewed
He Yong, Michiko Shimoda, Yoko Ono, Itzel Bustos Villalobos, Mitra A, Maverakis E
JAMA dermatology Vol. 151 ( 6 ) page: 646 - 650 2015.6
Multimodal therapy of idiopathic gangrenosum Invited Reviewed
Victoria Sharon, Barbara Burrall, Forum Patel, Yong He, Thomas Konia, Itzel Bustos Villalobos, Maverakis E
Dermatology on line Journal Vol. 20 ( 6 ) page: 6 2014
Lack of CD4+CD25+Foxp3+ regulatory T cells is associated with resistance to intravenous immunoglobulin therapy in patients with Kawasaki disease Invited Reviewed
Yu Hirabayashi, Yoshiyuki Takahashi, Yinyan Xu, Kazuyuki Akane, Itzel Bustos Villalobos, Yusuke Okuno, Shinji Hasegawa, Hideki Muramatsu, Asahito Hama, Taichi Kato, S. Kojima
European Journal of Pediatrics Vol. 172 ( 6 ) 2013
The Role of Technology in Education Today and into the Future Invited
Academic Consortium 21 on line international Forum 2020.12.8
Program Mixer on Summer Camp Bologna 2020 International conference
GAME/ TEI
Started on line joint clinical case discussions internationally International coauthorship
Itzel Bustos
PD-L1 as target for the development of a new oncolytic virus
Grant number:18K15274 2018.4 - 2020.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists
Bustos Itzel
Authorship:Principal investigator
Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )
The purpose of this study was to develop a novel oncolytic virus that not only has a tropism for PD-L1-expressing cells but also has a function as an immune checkpoint inhibitor. We have succeeded in constructing the anti-PD-L1 antibody gene vector, but have not yet created the desired virus. The combination of HF10 and anti-PD-L1 antibody against the bilateral flank tumors of mouse squamous cell carcinoma SCC VII showed a strong antitumor effect on the bilateral tumors. It was suggested that the infiltration of immune cells into the tumor is involved in this enhancement of antitumor effect.
Pediatrics
2022
Introduction to Neuroanatomy
2022
Medical English 4th year
2022
On line joint clinical case discussion
2020
Introduction to endocrinology
2020
Basic of neurology
2020
Pediatrics
2020
USMLE quiz review
2020