Organization
Graduate School of Medicine Designated assistant professor
Title
Designated assistant professor
KOCHIN Vitaly
Degree 2
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PhD （ 2009.11 Abo Akademi University, Turku Finland ）
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MSc with honours in Pharmacy （ 2002.6 Sechenov Moscow Medical University ）
Research History 9
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Nagoya University School of Medicine Dpt. of Immunology Assistant professor
2016.5
Country：Japan
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Sapporo Medical University Department of Pathology Postdoctoral fellow
2010.8 - 2016.4
Country：Japan
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Abo Akademi University Department of Biology Postdoctoral Fellow
2009.11 - 2010.6
Country：Finland
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Northwestern University School of Medicine Department of Cell and Molecular Biology Visiting researcher
2008.3 - 2008.6
Country：United States
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Max Planck Institute for Biophysical Chemistry Nanobiophotonics Visiting researcher
2008.1
Country：Germany
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Woods Hole Marine Biological Laboratory Physiology course Visiting researcher
2007.6 - 2007.8
Country：United States
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Ludwig Insitute for Cancer Research Protein Structure Analysis Laboratory Visiting researcher
2005.10 - 2005.12
Country：Sweden
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Max-Plank Institute of Biochemsitry Protein phosphorylation laboratory Visiting researcher
2004.4 - 2004.5
Country：Germany
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Sechenov Moscow Medical University Department of Pharmaceutical chemistry Research assistant
2001.9 - 2002.9
Country：Russian Federation
Education 2
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Abo Akademi University Graduate School, Division of Biological Science Cell biology and biochemistry
2003.1 - 2009.11
Country： Finland
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Sechenov Moscow Medical University Faculty of Pharmaceutical Science
1997.9 - 2002.6
Country： Russian Federation
Papers 8
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Kikuchi Y, Tokita S, Hirama T, Kochin V, Nakatsugawa M, Shinkawa T, Hirohashi Y, Tsukahara T, Hata F, Takemasa I, Sato N, Kanaseki T, Torigoe T.
Cancer Immunol Res 2021.8
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The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies Invited Reviewed
Kumagai S, Togashi Y, Kamada T, Sugiyama E, Nishinakamura H, Takeuchi Y, Vitaly K, Itahashi K, Maeda Y, Matsui S, Shibahara T, Yamashita Y, Irie T, Tsuge A, Fukuoka S, Kawazoe A, Udagawa H, Kirita K, Aokage K, Ishii G, Kuwata T, Nakama K, Kawazu M, Ueno T, Yamazaki N, Goto K, Tsuboi M, Mano H, Doi T, Shitara K, Nishikawa H.
Nature Immunology page： 1346 - 1358 2020.11
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Upstream Position of Proline Defines Peptide-HLA Class I Repertoire Formation and CD8(+) T Cell Responses
Hongo Ayumi, Kanaseki Takayuki, Tokita Serina, Kochin Vitaly, Miyamoto Sho, Hashino Yuiko, Codd Amy, Kawai Noriko, Nakatsugawa Munehide, Hirohashi Yoshihiko, Sato Noriyuki, Torigoe Toshihiko
JOURNAL OF IMMUNOLOGY Vol. 202 ( 10 ) page： 2849-2855 2019.5
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Meddling with meddlers: curbing regulatory T cells and augmenting antitumor immunity
Kochin Vitaly, Nishikawa Hiroyoshi
NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 81 ( 1 ) page： 1-18 2019.2
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The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer.
Miyamoto S, Kochin V, Kanaseki T, Hongo A, Tokita S, Kikuchi Y, Takaya A, Hirohashi Y, Tsukahara T, Terui T, Ishitani K, Hata F, Takemasa I, Miyazaki A, Hiratsuka H, Sato N, Torigoe T
Cancer immunology research Vol. 6 ( 3 ) page： 358-369 2018.3
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Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer.
Vol. 8 ( 15 ) page： 24706-24718 2017.4
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HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses
Kochin Vitaly, Kanaseki Takayuki, Tokita Serina, Miyamoto Sho, Shionoya Yosuke, Kikuchi Yasuhiro, Morooka Daichi, Hirohashi Yoshihiko, Tsukahara Tomohide, Watanabe Kazue, Toji Shingo, Kokai Yasuo, Sato Noriyuki, Torigoe Toshihiko
ONCOIMMUNOLOGY Vol. 6 ( 4 ) page： e1293214 2017
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Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition.
Shionoya Y, Kanaseki T, Miyamoto S, Tokita S, Hongo A, Kikuchi Y, Kochin V, Watanabe K, Horibe R, Saijo H, Tsukahara T, Hirohashi Y, Takahashi H, Sato N, Torigoe T
Oncoimmunology Vol. 6 ( 2 ) page： e1274476 2017
KAKENHI (Grants-in-Aid for Scientific Research) 3
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がん免疫療法における免疫関連有害事象発症のメカニズム解明
2021.4 - 2024.3
日本学術振興会 日本学術振興会
Authorship：Principal investigator
Grant amount：\3100000
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Search for cancer-specific antigens by analyzing human natural peptide repertoire
2014.4 - 2016.3
Grant-in-Aid for Scientific Research
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Search for cancer-specific antigens by analyzing human natural peptide repertoire
2014.4 - 2016.3
Grant-in-Aid for Scientific Research