Updated on 2024/09/18

写真a

 
NISHIWAKI Satoshi
 
Organization
Nagoya University Hospital Lecturer
Graduate School
Graduate School of Medicine
Title
Lecturer

Degree 1

  1. 博士(医学) ( 2012.3   名古屋大学 ) 

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    2009.4 - 2012

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    Country: Japan

  2. Nagoya University   Faculty of Medicine

    1998.4 - 2004

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    Country: Japan

Awards 5

  1. 日本白血病研究基金若手奨励研究賞

    2015.11   日本白血病研究基金  

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    Award type:Award from publisher, newspaper, foundation, etc.  Country:Japan

  2. 2012 ASCO Annual Meeting Merit Award

    2012.6   American Society of Clinical Oncology  

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    Award type:Award from international society, conference, symposium, etc.  Country:United States

  3. 名古屋大学学術奨励賞

    2011.7   名古屋大学  

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    Country:Japan

  4. 日本白血病研究基金一般研究賞(日本臨床血液学会推薦)

    2008.11   日本白血病研究基金  

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    Award type:Award from publisher, newspaper, foundation, etc.  Country:Japan

  5. 日本造血細胞移植学会奨励賞

    2008.2   日本造血細胞移植学会  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

 

Papers 70

  1. Utility of allogeneic stem cell transplantation for adult Ph plus ALL with complete molecular remission

    Nishiwaki, S; Sugiura, I; Fujisawa, S; Hatta, Y; Atsuta, Y; Doki, N; Kurahashi, S; Ueda, Y; Dobashi, N; Maeda, T; Matsumura, I; Tanaka, M; Kako, S; Ichinohe, T; Fukuda, T; Ohtake, S; Ishikawa, Y; Miyazaki, Y; Kiyoi, H

    AMERICAN JOURNAL OF HEMATOLOGY   Vol. 99 ( 5 ) page: 806 - 815   2024.5

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  2. Reduced-intensity allogenic transplantation for children and adolescents with Philadelphia chromosome-positive acute lymphoblastic leukemia

    Ishida, H; Arakawa, Y; Hasegawa, D; Usami, I; Hashii, Y; Arai, Y; Nishiwaki, S; Keino, D; Kato, K; Sato, M; Yoshida, N; Ozawa, Y; Okada, K; Hidaka, M; Yuza, Y; Tanaka, M; Watanabe, K; Takita, J; Kosaka, Y; Fujita, N; Tanaka, J; Sato, A; Atsuta, Y; Imamura, T

    ANNALS OF HEMATOLOGY   Vol. 103 ( 3 ) page: 1015 - 1016   2024.3

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  3. Dabrafenib and trametinib administration in patients with BRAF V600E/R or non-V600 BRAF mutated advanced solid tumours (BELIEVE, NCCH1901): a multicentre, open-label, and single-arm phase II trial

    Shimoi, T; Sunami, K; Tahara, M; Nishiwaki, S; Tanaka, S; Baba, E; Kanai, M; Kinoshita, I; Shirota, H; Hayashi, H; Nishida, N; Kubo, T; Mamesaya, N; Ando, Y; Okita, N; Shibata, T; Nakamura, K; Yamamoto, N

    ECLINICALMEDICINE   Vol. 69   page: 102447   2024.3

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  4. Characteristics and prognosis of patients with COVID-19 and hematological diseases in Japan: a cross-sectional study

    Minakata, D; Uchida, T; Nakano, A; Takase, K; Tsukada, N; Kosugi, H; Kawata, E; Nakane, T; Takahashi, H; Endo, T; Nishiwaki, S; Fujiwara, H; Saito, AM; Saito, TI; Akashi, K; Matsumura, I; Mitani, K

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 119 ( 2 ) page: 183 - 195   2024.2

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  5. Impact of MRD on clinical outcomes of unrelated hematopoietic stem cell transplantation in patients with Ph<SUP>+</SUP> ALL: A retrospective nationwide study

    Hirabayashi, S; Kondo, T; Nishiwaki, S; Mizuta, S; Doki, N; Fukuda, T; Uchida, N; Ozawa, Y; Kanda, Y; Imanaka, R; Takahashi, S; Ishikawa, J; Yano, S; Nakamae, H; Eto, T; Kimura, T; Tanaka, J; Ichinohe, T; Atsuta, Y; Kako, S

    AMERICAN JOURNAL OF HEMATOLOGY   Vol. 98 ( 10 ) page: 1606 - 1618   2023.10

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  6. Phase II trial of dabrafenib and trametinib in patients with BRAFV600E/R or non-BRAFV600 mutated advanced solid tumors: Results from the BELIEVE trial (NCCH1901).

    Tahara, M; Shimoi, T; Nishiwaki, S; Tanaka, S; Baba, E; Muto, M; Kinoshita, I; Sakai, D; Tabata, M; Hayashi, H; Ishioka, C; Mamesaya, N; Yamamoto, N

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 41 ( 16 )   2023.6

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  7. High-risk Combinations of Additional Chromosomal Abnormalities in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia: JALSG Ph plus ALL TKI-SCT Study

    Nishiwaki, S; Sugiura, I; Fujisawa, S; Hatta, Y; Atsuta, Y; Doki, N; Kurahashi, S; Ueda, Y; Dobashi, N; Maeda, T; Taniguchi, Y; Tanaka, M; Kako, S; Ichinohe, T; Fukuda, T; Ohtake, S; Ishikawa, Y; Kiyoi, H; Matsumura, I; Miyazaki, Y

    HEMASPHERE   Vol. 7 ( 6 ) page: e899   2023.6

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  8. Autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia is safe but poses challenges for long-term maintenance of molecular remission: Results of the Auto-Ph17 study

    Nishiwaki, S; Sugiura, I; Sato, T; Kobayashi, M; Osaki, M; Sawa, M; Adachi, Y; Okabe, M; Saito, S; Morishita, T; Kohno, A; Nishiyama, T; Iida, H; Kurahashi, S; Kuwatsuka, Y; Sugiyama, D; Ito, S; Nishikawa, H; Kiyoi, H

    EJHAEM   Vol. 4 ( 2 ) page: 358 - 369   2023.5

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  9. Poor Prognostic Combination of Additional Chromosomal Abnormalities in Ph plus ALL : JALSG Ph plus ALL TKI- SCT Study

    Nishiwaki, S; Sugiura, I; Fujisawa, S; Hatta, Y; Doki, N; Kurahashi, S; Ueda, Y; Dobashi, N; Maeda, T; Taniguchi, Y; Tanaka, M; Kako, S; Ichinohe, T; Fukuda, T; Atsuta, Y; Ohtake, S; Ishikawa, Y; Kiyoi, H; Matsumura, I; Miyazaki, Y

    BLOOD   Vol. 140   page: 6030 - 6032   2022.11

  10. Improvements in allogeneic hematopoietic cell transplantation outcomes for adults with ALL over the past 3 decades

    Nishiwaki, S; Akahoshi, Y; Morita-Fujita, M; Shimizu, H; Uchida, N; Ozawa, Y; Fukuda, T; Tanaka, M; Ikegame, K; Ota, S; Katayama, Y; Takahashi, S; Kawakita, T; Ara, T; Onizuka, M; Kimura, T; Tanaka, J; Atsuta, Y; Arai, Y

    BLOOD ADVANCES   Vol. 6 ( 15 ) page: 4558 - 4569   2022.8

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  11. Dasatinib-based 2-step induction for adults with Philadelphia chromosome-positive acute lymphoblastic leukemia

    Sugiura, I; Doki, N; Hata, T; Cho, R; Ito, T; Suehiro, Y; Tanaka, M; Kako, S; Matsuda, M; Yokoyama, H; Ishikawa, Y; Taniguchi, Y; Hagihara, M; Ozawa, Y; Ueda, Y; Hirano, D; Sakura, T; Tsuji, M; Kamae, T; Fujita, H; Hiramoto, N; Onoda, M; Fujisawa, S; Hatta, Y; Dobashi, N; Nishiwaki, S; Atsuta, Y; Kobayashi, Y; Hayakawa, F; Ohtake, S; Naoe, T; Miyazaki, Y

    BLOOD ADVANCES   Vol. 6 ( 2 ) page: 624 - 636   2022.1

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  12. COVID-19 Pandemic and Trends in Clinical Trials: A Multi-Region and Global Perspective

    Nishiwaki, S; Ando, Y

    FRONTIERS IN MEDICINE   Vol. 8   page: 812370   2021.12

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  13. The differential effect of disease status at allogeneic hematopoietic cell transplantation on outcomes in acute myeloid and lymphoblastic leukemia

    Yanada, M; Konuma, T; Yamasaki, S; Mizuno, S; Hirabayashi, S; Nishiwaki, S; Uchida, N; Doki, N; Tanaka, M; Ozawa, Y; Sawa, M; Eto, T; Kawakita, T; Ota, S; Fukuda, T; Onizuka, M; Kimura, T; Atsuta, Y; Kako, S; Yano, S

    ANNALS OF HEMATOLOGY   Vol. 100 ( 12 ) page: 3017 - 3027   2021.12

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  14. Newly proposed threshold and validation of white blood cell count at diagnosis for Philadelphia chromosome-positive acute lymphoblastic leukemia: risk assessment of relapse in patients with negative minimal residual disease at transplantation-a report from the Adult Acute Lymphoblastic Leukemia Working Group of the JSTCT

    Akahoshi, Y; Arai, Y; Nishiwaki, S; Tachibana, T; Shinohara, A; Doki, N; Uchida, N; Tanaka, M; Kanda, Y; Shiratori, S; Ozawa, Y; Shono, K; Katayama, Y; Tanaka, J; Fukuda, T; Atsuta, Y; Kako, S

    BONE MARROW TRANSPLANTATION   Vol. 56 ( 11 ) page: 2842 - 2848   2021.11

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  15. Optimal treatment for Philadelphia-negative acute lymphoblastic leukemia in first remission in the era of high-intensity chemotherapy

    Kako, S; Hayakawa, F; Imai, K; Tanaka, J; Mizuta, S; Nishiwaki, S; Kanamori, H; Mukae, J; Ozawa, Y; Kondo, T; Fukuda, T; Ichinohe, T; Ota, S; Tanaka, Y; Murayama, T; Kurahashi, S; Sakura, T; Usui, N; Ohtake, S; Kiyoi, H; Matsumura, I; Miyazaki, Y; Atsuta, Y

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 114 ( 5 ) page: 608 - 619   2021.11

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  16. Minimal residual disease (MRD) positivity at allogeneic hematopoietic cell transplantation, not the quantity of MRD, is a risk factor for relapse of Philadelphia chromosome-positive acute lymphoblastic leukemia

    Akahoshi, Y; Arai, Y; Nishiwaki, S; Mizuta, S; Marumo, A; Uchida, N; Kanda, Y; Sakai, H; Takada, S; Fukuda, T; Fujisawa, S; Ashida, T; Tanaka, J; Atsuta, Y; Kako, S

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 113 ( 6 ) page: 832 - 839   2021.6

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  17. Phase I clinical trial of intra-bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation

    Goto, T; Murata, M; Nishida, T; Terakura, S; Kamoshita, S; Ishikawa, Y; Ushijima, Y; Adachi, Y; Suzuki, S; Kato, K; Hirakawa, A; Nishiwaki, S; Nishio, N; Takahashi, Y; Kodera, Y; Matsushita, T; Kiyoi, H

    STEM CELLS TRANSLATIONAL MEDICINE   Vol. 10 ( 4 ) page: 542 - 553   2021.4

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  18. Machine learning-aided risk stratification in Philadelphia chromosome-positive acute lymphoblastic leukemia

    Nishiwaki, S; Sugiura, I; Koyama, D; Ozawa, Y; Osaki, M; Ishikawa, Y; Kiyoi, H

    BIOMARKER RESEARCH   Vol. 9 ( 1 ) page: 13   2021.2

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  19. Measurable residual disease affects allogeneic hematopoietic cell transplantation in Ph<SUP>+</SUP> ALL during both CR1 and CR2

    Nishiwaki, S; Akahoshi, Y; Mizuta, S; Shinohara, A; Hirabayashi, S; Noguchi, Y; Fukuda, T; Uchida, N; Tanaka, M; Onizuka, M; Ozawa, Y; Ota, S; Shiratori, S; Onishi, Y; Kanda, Y; Sawa, M; Tanaka, J; Atsuta, Y; Kako, S

    BLOOD ADVANCES   Vol. 5 ( 2 ) page: 584 - 592   2021.1

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  20. <i>In vivo</i> tracking of transplanted macrophages with near infrared fluorescent dye reveals temporal distribution and specific homing in the liver that can be perturbed by clodronate liposomes

    Nishiwaki, S; Saito, S; Takeshita, K; Kato, H; Ueda, R; Takami, A; Naoe, T; Ogawa, M; Nakayama, T

    PLOS ONE   Vol. 15 ( 12 ) page: e0242488   2020.12

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  21. Multi-Lineage <i>BCR-ABL</i> Expression in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Is Associated With Improved Prognosis but No Specific Molecular Features

    Nishiwaki, S; Kim, JH; Ito, M; Maeda, M; Okuno, Y; Koyama, D; Ozawa, Y; Gunji, M; Osaki, M; Kitamura, K; Ushijima, Y; Ishikawa, Y; Miyamura, K; Sugiura, I; Kiyoi, H

    FRONTIERS IN ONCOLOGY   Vol. 10   page: 586567   2020.10

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  22. Gap between pediatric and adult approvals of molecular targeted drugs

    Nishiwaki, S; Ando, Y

    SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page: 17145   2020.10

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  23. Reduced-intensity conditioning is a reasonable alternative for Philadelphia chromosome-positive acute lymphoblastic leukemia among elderly patients who have achieved negative minimal residual disease: a report from the Adult Acute Lymphoblastic Leukemia Working Group of the JSHCT

    Akahoshi, Y; Nishiwaki, S; Arai, Y; Harada, K; Najima, Y; Kanda, Y; Shono, K; Ota, S; Fukuda, T; Uchida, N; Shiratori, S; Tanaka, M; Tanaka, J; Atsuta, Y; Kako, S

    BONE MARROW TRANSPLANTATION   Vol. 55 ( 7 ) page: 1317 - 1325   2020.7

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  24. A consideration for efficient unrelated hematopoietic stem cell source acquisition-from an experience of Japan

    Nishiwaki, S; Miyamura, K; Kanda, Y; Takanashi, M; Uchida, N; Fukuda, T; Ikegame, K; Ohashi, K; Eto, T; Ozawa, Y; Shiratori, S; Iwato, K; Matsuoka, K; Hidaka, M; Ichinohe, T; Atsuta, Y; Kodera, Y; Okamoto, S

    BONE MARROW TRANSPLANTATION   Vol. 55 ( 3 ) page: 657 - 660   2020.3

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  25. Myeloablative Vs Reduced-Intensity Conditioning for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Among Patients over 50 Years Old Who Achieved Negative Minimal Residual Disease

    Akahoshi, Y; Nishiwaki, S; Arai, Y; Harada, K; Doki, N; Kanda, Y; Shono, K; Ohta, S; Fukuda, T; Uchida, N; Tanakaw, J; Atsuta, Y; Kako, S

    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   Vol. 26 ( 3 ) page: S162 - S163   2020.3

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    Language:Japanese  

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  26. Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells

    Goto, T; Murata, M; Nishida, T; Terakura, S; Kamoshita, S; Ishikawa, Y; Ushijima, Y; Adachi, Y; Kato, K; Hirakawa, A; Nishiwaki, S; Nishio, N; Takahashi, Y; Kodera, Y; Matsushita, T; Kiyoi, H

    BLOOD   Vol. 134   2019.11

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    Language:Japanese  

    DOI: 10.1182/blood-2019-122101

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  27. Dasatinib-Based Two-Step Induction Prior to Allogeneic Hematopoietic Cell Transplantation for Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of the JALSG Ph+ALL213 Study

    Sugiura, I; Doki, N; Hata, T; Cho, R; Ito, T; Suehiro, Y; Kanamori, H; Kako, S; Matsuda, M; Yokoyama, H; Taniguchi, Y; Hagihara, M; Ozawa, Y; Fujisawa, S; Dobashi, N; Hatta, Y; Asada, N; Ohashi, K; Onishi, Y; Shiro, K; Nishiwaki, S; Atsuta, Y; Hayakawa, F; Ohtake, S; Miyazaki, Y

    BLOOD   Vol. 134   2019.11

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    Language:Japanese  

    DOI: 10.1182/blood-2019-123382

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  28. The Optimal Treatment Strategy for Adult Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First Complete Remission in the Era of High-Intensity Chemotherapy

    Kako, S; Hayakawa, F; Imai, K; Tanaka, J; Mizuta, S; Nishiwaki, S; Kanamori, H; Doki, N; Uchida, N; Ikegame, K; Fukuda, T; Ichinohe, T; Ota, S; Tanaka, Y; Murayama, T; Kurahashi, S; Sakura, T; Usui, N; Ohtake, S; Kiyoi, H; Matsumura, I; Miyazaki, Y; Atsuta, Y

    BLOOD   Vol. 134   2019.11

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    Language:Japanese  

    DOI: 10.1182/blood-2019-126012

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  29. Application of the New Process for Unapproved Drug Use: Dilemma of Universal Health Care Coverage in Japan

    Nishiwaki, S; Ando, Y

    JOURNAL OF GLOBAL ONCOLOGY   Vol. 5   page: 1 - 3   2019.11

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  30. Different impact of BCR-ABL transcripts on allogeneic hematopoietic cell transplantation from different graft sources for Ph plus ALL with minimal residual disease

    Nishiwaki, S; Mizuta, S; Ohashi, K; Fukuda, T; Uchida, N; Tachibana, T; Onizuka, M; Ozawa, Y; Onishi, Y; Takahashi, S; Eto, T; Nakamae, H; Tanaka, J; Ichinohe, T; Atsuta, Y; Kako, S

    AMERICAN JOURNAL OF HEMATOLOGY   Vol. 94 ( 11 ) page: E301 - E305   2019.11

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  31. Tyrosine kinase inhibitor prophylaxis after transplant for Philadelphia chromosome-positive acute lymphoblastic leukemia

    Akahoshi, Y; Nishiwaki, S; Mizuta, S; Ohashi, K; Uchida, N; Tanaka, M; Fukuda, T; Ozawa, Y; Takahashi, S; Onizuka, M; Shiratori, S; Nakamae, H; Kanda, Y; Ichinohe, T; Atsuta, Y; Kako, S

    CANCER SCIENCE   Vol. 110 ( 10 ) page: 3255 - 3266   2019.10

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  32. Allogeneic Stem Cell Transplantation for Acute Lymphoblastic Leukemia in Adolescents and Young Adults

    Hangai, M; Urayama, KY; Tanaka, J; Kato, K; Nishiwaki, S; Koh, K; Noguchi, M; Kato, K; Yoshida, N; Sato, M; Goto, H; Yuza, Y; Hashii, Y; Atsuta, Y; Mizuta, S; Kato, M

    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   Vol. 25 ( 8 ) page: 1597 - 1602   2019.8

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  33. Prophylactic Use of Tyrosine Kinase Inhibitors in Patients with Negative Results for Minimal Residual Disease after Allogeneic Stem Cell Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

    Akahoshi, Y; Nishiwaki, S; Mizuta, S; Ohashi, K; Uchida, N; Kanamori, H; Fukuda, T; Ozawa, Y; Kanda, Y; Ichinohe, T; Atsuta, Y; Kako, S

    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   Vol. 25 ( 3 )   2019.3

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  34. Availability of HLA-allele-matched unrelated donors: estimation from haplotype frequency in the Japanese population.

    Nishiwaki S, Tanaka H, Kojima H, Okamoto S

    Bone marrow transplantation   Vol. 54 ( 2 ) page: 300 - 303   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41409-018-0263-9

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  35. Optimal Interval for Detection of Molecular Relapse after Stop of TKI in Ph plus ALL Calculating By M Kinetics

    Miyamura, K; Nishiwaki, S

    BLOOD   Vol. 132   2018.11

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  36. Outcomes of strategic alternative donor selection or suspending donor search based on Japan Marrow Donor Program coordination status

    Kawashima Naomi, Nishiwaki Satoshi, Shimizu Naoko, Kamoshita Sonoko, Watakabe Kyoko, Yokohata Emi, Kurahashi Shingo, Ozawa Yukiyasu, Miyamura Koichi

    INTERNATIONAL JOURNAL OF HEMATOLOGY   Vol. 107 ( 5 ) page: 551 - 558   2018.5

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    DOI: 10.1007/s12185-018-2413-7

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  37. Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol

    Goto, T; Murata, M; Terakura, S; Nishida, T; Adachi, Y; Ushijima, Y; Shimada, K; Ishikawa, Y; Hayakawa, F; Nishio, N; Nishiwaki, S; Hirakawa, A; Kato, K; Takahashi, Y; Kiyoi, H

    MEDICINE   Vol. 97 ( 17 ) page: e0449   2018.4

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  38. Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia: A study protocol for a multicenter exploratory prospective study (Auto-Ph17 study) Reviewed

    Nishiwaki S, Sugiura I, Miyata Y, Saito S, Sawa M, Nishida T, Miyamura K, Kuwatsuka Y, Kohno A, Yuge M, Kasai M, Iida H, Kurahashi S, Osaki M, Goto T, Terakura S, Murata M, Nishikawa H, Kiyoi H

    Medicine   Vol. 96 ( 52 ) page: e9568   2017.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  39. Successful treatment with allogeneic stem cell transplantation followed by DLI and TKIs for e6a2 BCR-ABL-positive acute myeloid leukaemia: A case report and literature review Reviewed

    Harada Y, Nishiwaki S, Sugimoto T, Onodera K, Goto T, Sato T, Kamoshita S, Kawashima N, Seto A, Okuno S, Yamamoto S, Iwasaki T, Ozawa Y, Miyamura K, Akatsuka Y, Sugiura I

    Medicine   Vol. 96 ( 50 ) page: e9160   2017.12

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  40. Impact of Synchronous Multiple Primary Malignant Tumors on Newly Diagnosed Hematological Malignancies Reviewed

    Nishiwaki S, Okuno S, Suzuki K, Kurahashi S, Sugiura I

    Clinical Lymphoma, Myeloma & Leukemia   Vol. 17 ( 12 ) page: E79 - E85   2017.12

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    DOI: 10.1016/j.clml.2017.09.006

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  41. Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia: A study protocol for a multicenter exploratory prospective study (Auto-Ph17 study)

    Nishiwaki, S; Sugiura, I; Miyata, Y; Saito, S; Sawa, M; Nishida, T; Miyamura, K; Kuwatsuka, Y; Kohno, A; Yuge, M; Kasai, M; Iida, H; Kurahashi, S; Osaki, M; Goto, T; Terakura, S; Murata, M; Nishikawa, H; Kiyoi, H

    MEDICINE   Vol. 96 ( 52 ) page: e9568   2017.12

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  42. Successful treatment with allogeneic stem cell transplantation followed by DLI and TKIs for e6a2 <i>BCR</i>-<i>ABL</i>-positive acute myeloid leukaemia A case report and literature review

    Harada, Y; Nishiwaki, S; Sugimoto, T; Onodera, K; Goto, T; Sato, T; Kamoshita, S; Kawashima, N; Seto, A; Okuno, S; Yamamoto, S; Iwasaki, T; Ozawa, Y; Miyamura, K; Akatsuka, Y; Sugiura, I

    MEDICINE   Vol. 96 ( 50 ) page: e9160   2017.12

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  43. Prognostic impact of synchronous multiple primary malignant tumors on newly diagnosed hematological malignancies

    Nishiwaki, S; Okuno, S; Suzuki, K; Kurahashi, S; Sugiura, I

    ANNALS OF ONCOLOGY   Vol. 28   2017.11

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  44. Effective chemomobilization with etoposide and cytarabine (EC regimen) in lymphoma patients: a single-center, retrospective, observational study.

    Koyama D, Nishiwaki S, Harada Y, Yamamoto S, Kurahashi S, Sugimoto T, Iwasaki T, Sugiura I

    Japanese journal of clinical oncology   Vol. 47 ( 9 ) page: 820 - 825   2017.9

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    DOI: 10.1093/jjco/hyx076

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  45. Effective chemomobilization with etoposide and cytarabine (EC regimen) in lymphoma patients: a single-center, retrospective, observational study Reviewed

    Koyama D, Nishiwaki S, Harada Y, Yamamoto S, Kurahashi S, Sugimoto T, Iwasaki T, Sugiura I

    Japanese Journal of Clinical Oncology   Vol. 47 ( 9 ) page: 820-825   2017.9

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  46. Increase of bone marrow macrophages and CD8<SUP>+</SUP> T lymphocytes predict graft failure after allogeneic bone marrow or cord blood transplantation

    Kawashima, N; Terakura, S; Nishiwaki, S; Koyama, D; Ozawa, Y; Ito, M; Miyamura, K

    BONE MARROW TRANSPLANTATION   Vol. 52 ( 8 ) page: 1164 - 1170   2017.8

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  47. PROGNOSTIC IMPACT OF SYNCHRONOUS MULTIPLE PRIMARY MALIGNANT TUMORS ON NEWLY DIAGNOSED LYMPHOMA PATIENTS

    Nishiwaki, S; Okuno, S; Suzuki, K; Kurahashi, S; Sugiura, I

    HAEMATOLOGICA   Vol. 102   page: 700 - 700   2017.6

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  48. Clinical efficacy of fecal occult blood test and colonoscopy for dasatinib-induced hemorrhagic colitis in CML patients

    Nishiwaki, S; Maeda, M; Yamada, M; Okuno, S; Harada, Y; Suzuki, K; Kurahashi, S; Urano, F; Okamura, S; Sugiura, I

    BLOOD   Vol. 129 ( 1 ) page: 126 - 128   2017.1

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  49. Clinical efficacy of fecal occult blood test followed by colonoscopy for dasatinib-induced hemorrhagic colitis in CML patients Reviewed

    Nishiwaki S, Maeda M, Yamada M, Okuno S, Harada Y, Suzuki K, Kurahashi S, Urano F, Okamura S, Sugiura I

    Blood   Vol. 129 ( 1 ) page: 126-128   2017.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  50. A new prognostic index to make short-term prognosis in MDS patients treated with azacitidine; a combination of p53 expression and cytogenetics Reviewed

    Nishiwaki S, Ito M, Watarai R, Okuno S, Harada Y, Yamamoto S, Suzuki K, Kurahashi S, Iwasaki T, Sugiura I

    Leukemia Research   Vol. 41   page: 21-6   2016

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  51. Impact of MRD and TKI on allogeneic hematopoietic cell transplantation for Ph+ALL: a study from the Adult ALL WG of the JSHCT Reviewed

    Nishiwaki S, Imai K, Mizuta S, Kanamori H, Ohashi K, Fukuda T, Onishi Y, Takahashi S, Uchida N, Eto T, Nakamae H, Yujiri T, Mori S, Nagamura-Inoue T, Suzuki R, Atsuta Y, Tanaka J

    Bone Marrow Transplant   Vol. 51 ( 1 ) page: 43-55   2016

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  52. Rules of providing cord blood for iPS cells for research Reviewed

    Nishiwaki S

    Cytotherapy   Vol. 17 ( 7 ) page: 1008   2015

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  53. Cervical epidural hematoma in a healthy donor presenting stroke mimic symptoms: a rare adverse event following peripheral blood stem cell apheresis Reviewed

    Terabe S, Nishiwaki S, Koyama D, Okuno S, Harada Y, Tomita H, Yoshihara H, Iwasaki T, Sugiura I

    Japanese Journal of Clinical Oncology   Vol. 45 ( 6 ) page: 584-7   2015

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  54. Roles of volunteers and professionals in medical development -insights from the development of Allo-HSCT Reviewed

    Nishiwaki S

    Japanese Journal of Clinical Oncology   Vol. 45 ( 5 ) page: 502-3   2015

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  55. Pros and Cons of Legislation on Allogeneic Hematopoietic Stem Cell Transplantation Reviewed

    Nishiwaki S

    Japanese Journal of Clinical Oncology   Vol. 45 ( 3 ) page: 311-2   2015

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  56. Pretransplant administration of imatinib for allo-HSCT in patients with BCR-ABL-positive acute lymphoblastic leukemia Reviewed

    Mizuta S, Matsuo K, Nishiwaki S, Imai K, Kanamori H, Ohashi K, Fukuda T, Onishi Y, Miyamura K, Takahashi S, Onizuka M, Atsuta Y, Suzuki R, Morishima Y, Kato K, Sakamaki H, Tanaka J

    Blood   Vol. 123 ( 15 ) page: 2325-32   2014

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  57. Complete nationwide survey on umbilical cord blood freezing bag breakage in Japan Reviewed

    Nishiwaki S, Izumi J

    Cytotherapy   Vol. 16 ( 11 ) page: 1590-4   2014

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  58. Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions Reviewed

    Nishiwaki S, Nakayama T, Murata M, Nishida T, Terakura S, Saito S, Kato T, Mizuno H, Imahashi N, Seto A, Ozawa Y, Miyamura K, Ito M, Takeshita K, Kato H, Toyokuni D, Nagao K, Ueda R, Naoe T

    PLoS One   Vol. 9 ( 5 ) page: e96252   2014

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  59. Provision of human immunodeficiency virus infection following cord blood transplantation Reviewed

    Nishiwaki S

    British Journal of Haematology   Vol. 166 ( 6 ) page: 956-7   2014

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  60. Impact of donor source on adult Philadelphia chromosome-negative acute lymphoblastic leukemia: a retrospective analysis from the Adult Acute Lymphoblastic Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation Reviewed

    Nishiwaki S, Miyamura K, Ohashi K, Kurokawa M, Taniguchi S, Fukuda T, Ikegame K, Takahashi S, Mori T, Imai K, Iida H, Hidaka M, Sakamaki H, Morisima Y, Kato K, Suzuki R, Tanaka J

    Annals of Oncology   Vol. 24 ( 6 ) page: 1594-602   2013

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  61. Allogeneic hematopoietic cell transplantation from alternative sources for adult Philadelphia chromosome-negative acute lymphoblastic leukemia: What should we choose when no HLA-matched related donor is available? Invited Reviewed

    Nishiwaki S, Atsuta Y, Tanaka J

    Bone Marrow Transplantation   Vol. 48 ( 11 ) page: 1369-76   2013

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  62. Allogeneic stem cell transplant for adult Philadelphia chromosome-negative acute lymphoblastic leukemia Reviewed

    Nishiwaki S, Miyamura K

    Leukemia & Lymphoma   Vol. 53 ( 4 ) page: 550-6   2012

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  63. Efficacy and safety of human adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis Reviewed

    Nishiwaki S, Nakayama T, Saito S, Mizuno H, Ozaki T, Takahashi Y, Maruyama S, Nishida T, Murata M, Kojima S,Naoe T

    International Journal of Hematology   Vol. 96 ( 3 ) page: 295-300   2012

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  64. Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation: macrophage-targeted steroid therapy Reviewed

    Nishiwaki S, Nakayama T, Murata M, Nishida T, Sugimoto K, Saito S, Kato T, Mizuno H, Imahashi N, Seto A, Ozawa Y, Goto T, Koyama D, Yokohata E, Kubota N, Kamoshita S, Miyamura K, Matsumoto K, Ito M, Naoe T

    International Journal of Hematology   Vol. 95 ( 4 ) page: 428-33   2012

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  65. Reduced-intensity versus conventional myeloablative conditioning for patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in complete remission Reviewed

    Nishiwaki S, Inamoto Y, Imamura M, Tsurumi H, Hatanaka K, Kawa K, Suzuki R, Miyamura K

    Blood   Vol. 117 ( 13 ) page: 3698-9   2011

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  66. Allogeneic stem cell transplantation for adult Philadelphia chromosome-negative acute lymphocytic leukemia: comparable survival rates but different risk factors between related and unrelated transplantation in first complete remission Reviewed

    Nishiwaki S, Inamoto Y, Sakamaki H, Kurokawa M, Iida H, Ogawa H, Fukuda T, Ozawa Y, Kobayashi N, Kasai M, Mori T, Iwato K, Yoshida T, Onizuka M, Kawa K, Morisima Y, Suzuki R, Atsuta Y, Miyamura K

    Blood   Vol. 116 ( 20 ) page: 4368-75   2010

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  67. Outcome of allogeneic bone marrow transplantation from unrelated donors for adult Philadelphia chromosome-negative acute lymphocytic leukemia in first complete-remission Reviewed

    Nishiwaki S, Terakura S, Yasuda T, Imahashi N, Sao H, Iida H, Kamiya Y, Niimi K, Morishita Y, Kohno A, Yokozawa T, Ohashi H, Sawa M, Kodera Y, Miyamura K

    International Journal of Hematology   Vol. 91 ( 3 ) page: 419-25   2010

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  68. Impact of Post-transplant Imatinib Administration on Philadelphia Chromosome-positive Acute Lymphoblastic Leukaemia Reviewed

    Nishiwaki S, Miyamura K, Kato C, Terakura S, Ohashi K, Sakamaki H, Nakao S, Harigae H, Kodera Y

    Anticancer Research   Vol. 30 ( 6 ) page: 2415-8   2010

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  69. Impact of macrophage infiltration of skin lesions on survival after allogeneic stem cell transplantation: a clue to refractory graft-versus-host disease Reviewed

    Nishiwaki S, Terakura S, Ito, M, Goto T, Seto A, Watanabe K, Yanagisawa M, Imanashi N, Tsukamoto S, Shimba M, Ozawa Y, Miyamura K

    Blood   Vol. 114 ( 14 ) page: 3113-6   2009

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  70. Impact of the basal metabolic ratio in predicting early deaths after allogeneic stem cell transplantation Reviewed

    Nishiwaki S, Miyamura K, Seto A, Watanabe K, Yanagisawa M, Imahashi N, Shimba M, Yasuda T, Kuwatsuka Y, Oba T, Terakura S, Kodera Y

    American Journal of Hematology   Vol. 84 ( 9 ) page: 608-11   2009

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Books 8

  1. EBM 血液疾患の治療<2019-2020>

    西脇 聡史( Role: Contributor ,  ステロイド抵抗性急性GVHDに対する救援療法)

    中外医学者  2018.10 

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    Total pages:567   Language:Japanese Book type:Scholarly book

  2. 日本臨床 増刊号 白血病学(下)・急性GVHDにおける皮膚マクロファージ浸潤の臨床的意義 

    西脇聡史( Role: Sole author)

    日本臨床社  2016 

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    Language:Japanese Book type:Scholarly book

  3. 日本臨床 増刊号 白血病学(上)・PCRによるMRDの検出

    宮村耕一, 西脇聡史( Role: Joint author)

    日本臨床社  2016 

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    Language:Japanese Book type:Scholarly book

  4. 血液内科・急性リンパ性白血病の分子病態

    西脇聡史( Role: Sole author)

    科学評論社  2014.2 

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    Language:Japanese Book type:Scholarly book

  5. 分子標的薬マスターガイド・血液 白血病 臓器別分子標的薬の位置づけ

    西脇聡史, 直江知樹( Role: Joint author)

    中外医学社  2014.7 

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    Language:Japanese Book type:Scholarly book

  6. 血液内科・成人フィラデルフィア染色体陰性急性リンパ性白血病に対する同種造血幹細胞移植

    西脇聡史( Role: Sole author)

    科学評論社  2011 

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    Language:Japanese Book type:Scholarly book

  7. 血液・腫瘍科・皮膚GVHDにおけるマクロファージ浸潤の臨床的意義:治療抵抗性GVHDの手がかりとなるか?

    西脇聡史, 伊藤雅文( Role: Joint author)

    科学評論社  2010 

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    Language:Japanese Book type:Scholarly book

  8. 内科・微小残存病変の定量 -治療の道しるべとなるか?-

    西脇聡史, 宮村耕一( Role: Joint author)

    南江堂  2007 

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    Language:Japanese Book type:Scholarly book

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Presentations 8

  1. Notes on efficient donor recruitment: estimation from haplotype frequency in the Japanese population International conference

    Satoshi Nishiwaki, Hidenori Tanaka, Hiroto, Kojima, Shinichiro Okamoto

    12th International Donor Registry Conference  

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    Event date: 2018.6

    Language:English   Presentation type:Poster presentation  

    Country:Germany  

  2. Prognostic impact of synchronous multiple primary malignant tumors on newly diagnosed hematological malignancies International conference

    Nishiwaki S, Okuno S, Suzuki K, Kurahashi S, Sugiura I

    ESMO Asia 2017 

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    Event date: 2017.11

    Language:English   Presentation type:Poster presentation  

    Venue:Singapore   Country:Singapore  

  3. Medical treatment system based on patient's request in Nagoya Univ Hospital-Experience of Auto-PBSCT using Thiotepa-

    Nishiwaki S

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    Event date: 2017.7

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Country:Japan  

  4. Significance of Fecal Occult Blood Test Followed by Colonoscopy for Asymptomatic Dasatinib-induced Hemorrhagic Colitis (CML1501 Study) International conference

    Nishiwaki S, Maeda M, Yamada M, Okuno S, Harada Y, Suzuki K, Kurahashi S, Urano F, Okamura S, Sugiura I

    58th Annual Meeting of American Society of Hematology 

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    Event date: 2016.12

    Language:English   Presentation type:Poster presentation  

    Venue:San Diego   Country:United States  

  5. Minimal residual disease-based strategies in hematopoietic cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia Invited International conference

    Nishiwaki S

    20th Winter Meeting of the KSBMT 

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    Event date: 2016.2

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Pyeongchang-gun   Country:Korea, Republic of  

  6. A new prognostic index to predict short-term prognosis in MDS patients treated with azacitidine; combination of p53 expression and cytogenetics International conference

    Nishiwaki S, Ito M, Okuno S, Harada Y, Yamamoto S, Iwasaki T, Sugiura I

    20th Congress of the European Hematology Association 

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    Event date: 2015.6

    Language:English   Presentation type:Poster presentation  

    Venue:Vienna   Country:Austria  

  7. ダサチニブによる無症候性出血性腸炎に対する便潜血検査と下部消化管内視鏡検査の有用性

    西脇聡史, 前多松喜, 山田雅弘, 奥野真吾, 原田靖彦, 鈴木弘太郎, 倉橋信悟, 浦野文博, 岡村正造, 杉浦勇

    第78回日本血液学会 総会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜2016・   Country:Japan  

  8. Ph(+)ALLにおけるMRDと移植成績 Invited

    西脇聡史, 宮村耕一

    第38回日本造血細胞移植学会総会 

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    Event date: 2016.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋   Country:Japan  

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. Multilateral prognostic factor analysis for Ph+ALL in the era of TKI

    Grant number:20K08730  2020.4 - 2023.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Nishiwaki Satoshi

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    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    Additional chromosomal abnormalities other than the Philadelphia chromosome were found in 63.6% of 206 cases of de novo Ph+ALL. The most frequent structural abnormality was +der(22)t(9;22). Among the 43 cases with +der(22)t(9;22), 67.4% had a complex karyotype with three or more chromosomal aberrations. Coexistence of +der(22)t(9;22) and complex karyotype was associated with significantly poorer survival and shorter time to recurrence. In multivariate analysis, +der(22)t(9;22) alone or complex karyotype alone were not significant factors, but coexistence of +der(22)t(9;22) and complex karyotype was a significant risk factor for survival. This study demonstrated that the coexistence of +der(22)t(9;22) and complex karyotype was a significant prognostic factor in Ph+ALL.

  2. Significance of BCR gene breakpoint in Ph + ALL

    Grant number:17K16186  2017.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    NISHIWAKI Satoshi

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    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

    Multi-lineage BCR-ABL expression (Multi-Ph) was defined in 21 of 59 patients (36%). BCR breakpoint was major in 17 of 21 Multi-Ph (81%). In such patients, BCR-ABL was detected at the multipotent progenitor level. However, no IKZF1 deletion patterns that were specific for Multi-Ph were identified. On the other hand, better survival rates were observed in patients with Multi-Ph compared with survival rates in those with uni-lineage BCR-ABL expression. In multivariate analyses, Multi-Ph was identified as a good prognostic factor for both overall survival and event-free survival. We confirmed Multi-Ph in more than one-third of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Although no specific molecular characteristics were identified, Multi-Ph was associated with better treatment outcomes.