Two loci contribute to age-related hearing loss resistance in the Japanese wild-derived inbred MSM/Ms mice Reviewed

Yasuda SP, Miyasaka Y, Hou X, Obara Y, Shitara H, Seki Y, Matsuoka K, Takahashi A, Wakai E, Hibino H, Takada T, Shiroishi T, Kominami R, Kikkawa Y

Biomedicines   Vol. 10 ( 9 ) page： 2221   2022.9

E3 ubiquitin ligase RNF123-deficient mice exhibit reduced parasitemia and mortality in rodent malaria (Plasmodium yoelii 17XL) infection Reviewed

Miyasaka Y, Niwa S, Masuya T, Ishii R, Kobayashi M, Horio F, Ohno T

Parasitol. Int.   Vol. 88   page： 102542   2022.6

UVB-Induced skin autoinflammation due to Nlrp1b mutation and its inhibition by anti-IL-1β antibody Reviewed

Murase Y, Takeichi T, Koseki J, Miyasaka Y, Muro Y, Ohno T, Shimamura T, Akiyama M

Front. Immunol.   Vol. 13   page： 876390   2022.6

Autoinflammatory keratinization disease with hepatitis and autism reveals roles for JAK1 kinase hyperactivity in autoinflammation Reviewed

Takeichi T, Lee JYW, Okuno Y, Miyasaka Y, Murase Y, Yoshikawa T, Tanahashi K, Nishida E, Okamoto T, Ito K, Muro Y, Sugiura K, Ohno T, McGrath JA, Akiyama M

Front. Immunol.   Vol. 12   page： 737747   2022.1

Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition, and Implication of CDH23 in Schizophrenia. Reviewed

Balan S, Ohnishi T, Watanabe A, Ohba H, Iwayama Y, Toyoshima M, Hara T, Hisano Y, Miyasaka Y, Toyota T, Shimamoto-Mitsuyama C, Maekawa M, Numata S, Ohmori T, Shimogori T, Kikkawa Y, Hayashi T, Yoshikawa T.

Schizophr. Bull.   Vol. 47 ( 4 ) page： 1190 - 1200   2021.7

Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice. Reviewed

Masuya T, Suzuki M, Tsujimura J, Kanamori S, Miyasaka Y, Ohno T, Murai A, Horio F, Kobayashi M.

PLoS One.   Vol. 15 ( 5 ) page： e0233087   2020.5

c.753A>G genome editing of a Cdh23 ahl allele delays age-related hearing loss and degeneration of cochlear hair cells in C57BL/6J mice. Reviewed

Yasuda SP, Seki Y, Suzuki S, Ohshiba Y, Hou X, Matsuoka K, Wada K, Shitara H, Miyasaka Y, Kikkawa Y.

Hear. Res.   Vol. 389   page： 107926   2020.4

SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation. Reviewed

Takeichi T, Hirabayashi T, Miyasaka Y, Kawamoto A, Okuno Y, Taguchi S, Tanahashi K, Murase C, Takama H, Tanaka K, Boeglin WE, Calcutt MW, Watanabe D, Kono M, Muro Y, Ishikawa J, Ohno T, Brash AR, Akiyama M.

J. Clin. Invest.   Vol. 130 ( 2 ) page： 890 - 903   2020.2

Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research. Reviewed

Ohno T, Miyasaka Y, Kuga M, Ushida K, Matsushima M, Kawabe T, Kikkawa Y, Mizuno M, Takahashi M

Exp. Anim.   Vol. 68 ( 3 ) page： 243 - 255   2019

OHC-TRECK: A Novel System Using a Mouse Model for Investigation of the Molecular Mechanisms Associated with Outer Hair Cell Death in the Inner Ear. Reviewed

Matsuoka K, Wada K, Miyasaka Y, Yasuda SP, Seki Y, Nishito Y, Yonekawa H, Taya C, Shitara H, Kikkawa Y.

Sci. Rep.   Vol. 9 ( 1 ) page： 5285   2019

Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta. Reviewed

Ohno T, Kai T, Miyasaka Y, Maruyama H, Ishih A, Kino H.

Parasitol. Int.   Vol. 67 ( 4 ) page： 357-361   2018

Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11. Reviewed

Maegawa T, Miyasaka Y, Kobayashi M, Babaya N, Ikegami H, Horio F, Takahashi M, Ohno T.

Mamm. Genome   Vol. 29 ( 3-4 ) page： 273 - 280   2018

A new missense mutation in the paired domain of the mouse Pax3 gene. Reviewed

Ohno T, Maegawa T, Katoh H, Miyasaka Y, Suzuki M, Kobayashi M, Horio F.

Exp. Anim.   Vol. 66 ( 3 ) page： 245-250   2017

A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells. Reviewed

Seki Y, Miyasaka Y, Suzuki S, Wada K, Yasuda SP, Matsuoka K, Ohshiba Y, Endo K, Ishii R, Shitara H, Kitajiri SI, Nakagata N, Takebayashi H, Kikkawa Y.

PLoS One   Vol. 12 ( 8 ) page： e0183477   2017

Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23. Reviewed

Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Hiromichi Y, Kikkawa Y.

Hum. Mol. Genet.   Vol. 25 ( 10 ) page： 2045-2059   2016

Quantitative trait loci on chromosome 5 for susceptibility to frequency-specific effects on hearing in DBA/2J mice. Reviewed

Suzuki S, Ishikawa M, Ueda T, Ohshiba Y, Miyasaka Y, Okumura K, Yokohama M, Taya C, Matsuoka K, Kikkawa Y.

Exp. Anim.   Vol. 64 ( 3 ) page： 241-251   2015

Dilation of the inferior colliculus and hypersensitivity to sound in Wnt1-cre and Wnt1-GAL4 double-transgenic mice. Reviewed

Nakajima M, Nishikawa C, Miyasaka Y, Kikkawa Y, Mori H, Tsuruta M, Okuyama S, Furukawa Y.

  Vol. 566   page： 236-240   2014

Compound Heterozygosity of the Functionally Null Cdh23v-ngt and Hypomorphic Cdh23ahl Alleles Leads to Early-onset Progressive Hearing Loss in Mice. Reviewed

Miyasaka Y, Suzuki S, Ohshiba Y, Watanabe K, Sagara Y, Yasuda SP, Matsuoka K, Shitara H, Yonekawa H, Kominami R, Kikkawa Y.

Exp. Anim.   Vol. 62 ( 4 ) page： 333-346   2013

Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms. Reviewed

Okumura K, Sato M, Saito M, Miura I, Wakana S, Mao JH, Miyasaka Y, Kominami R, Wakabayashi Y.

Carcinogenesis   Vol. 33   page： 2260-2268   2012

Advantages of a mouse model for human hearing impairment. Reviewed

Kikkawa Y, Seki Y, Okumura K, Ohshiba Y, Miyasaka Y, Suzuki S, Ozaki M, Matsuoka K, Noguchi Y, Yonekawa H.

Exp. Anim.   Vol. 61 ( 2 ) page： 85-98   2012

Bcl11b heterozygosity leads to age-related hearing loss and degeneration of outer hair cells of the mouse cochlea. Reviewed

Okumura H, Miyasaka Y, Morita Y, Nomura T, Mishima Y, Takahashi S, Kominami R.

Exp. Anim.   Vol. 60 ( 4 ) page： 355-361   2011