2026/09/02 更新

写真a

ヤナギサワ サトシ
柳澤 哲
YANAGISAWA Satoshi
所属
大学院医学系研究科 先進循環器治療学寄附講座 特任講師
職名
特任講師

学位 1

  1. 博士(医学) ( 2017年1月   名古屋大学 ) 

研究キーワード 5

  1. 心房細動

  2. 電気生理学

  3. ペースメーカ

  4. カテーテルアブレーション

  5. 不整脈

研究分野 1

  1. ライフサイエンス / 循環器内科学  / 不整脈学、電気生理学

所属学協会 6

  1. 日本不整脈心電学会

  2. 日本内科学会

  3. 日本循環器学会

  4. Asia Pacific Heart Rhythm Society (APHRS)

  5. European Heart Rhythm Association (EHRA)

  6. European Society of Cardiology (ESC)

▼全件表示

委員歴 7

  1. 日本内科学会東海支部 評議員  

  2. 日本不整脈心電学会 第3期評議員  

  3. EP Europace: International Editorial Consultant Board  

  4. Fellow of the European Heart Rhythm Association (FEHRA)  

  5. Fellow of the European Society of Cardiology (FESC)  

  6. Fellow of Japanese Circulation Society (FJCS)  

  7. Editorial Board of the Journal of Cardiovascular Electrophysiology (JCE)  

▼全件表示

 

論文 162

  1. Patient vulnerability associated with acute kidney injury after pulsed field ablation: A role for baseline biomarkers and haptoglobin phenotype.

    Suga K, Kato H, Yamazaki K, Sakurai T, Yamazoe S, Tsuzuki K, Ota T, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Heart rhythm   23 巻 ( 9 ) 頁: e1907 - e1915   2026年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2026.04.028

    PubMed

  2. Comparative analysis of hemolysis incidence across 3 different pulsed field ablation systems.

    Miyazawa H, Yanagisawa S, Inden Y, Fukushima T, Hiramatsu T, Adachi K, Teraoka T, Ota R, Miyamae K, Tanaka Y, Shimojo M, Tsuji Y, Murohara T

    Heart rhythm O2   7 巻 ( 8 ) 頁: 1407 - 1415   2026年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hroo.2026.04.009

    PubMed

  3. Enhanced contact of the PulseSelect catheter using the contact index during pulmonary vein isolation.

    Mizutani Y, Fujiwara G, Yanagisawa S, Murohara T

    Heart rhythm   23 巻 ( 8 ) 頁: 1862 - 1863   2026年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2025.08.039

    PubMed

  4. Temporal Coagulation Biomarker Profiles After Andexanet Alfa Use for Procedure-Related Cardiac Tamponade.

    Shimojo M, Inden Y, Kitahara T, Hiramatsu S, Tanaka Y, Hiramatsu T, Fukushima T, Adachi K, Teraoka T, Ota R, Yanagisawa S, Tsuji Y

    Journal of cardiovascular electrophysiology   37 巻 ( 8 ) 頁: 1808 - 1816   2026年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.70415

    PubMed

  5. Contact Index for PulseSelect Catheter Apposition: Validation by Transesophageal Echocardiography.

    Fujiwara G, Mizutani Y, Yanagisawa S, Murohara T

    Pacing and clinical electrophysiology : PACE     2026年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.70376

    PubMed

  6. Differential Time Course of LVEF Recovery Between Conduction System Pacing Versus Biventricular Pacing.

    Kato H, Yanagisawa S, Sakurai T, Suga K, Murakami H, Kada K, Tsuboi N, Ota R, Inden Y, Murohara T

    JACC. Asia   6 巻 ( 7 ) 頁: 1282 - 1285   2026年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacasi.2026.03.020

    PubMed

  7. Novel technique for leadless pacemaker implantation in the small right atrial appendage: a case report.

    Watanabe H, Mizutani Y, Watanabe J, Yanagisawa S, Murohara T

    European heart journal. Case reports   10 巻 ( 7 ) 頁: ytag514   2026年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/ehjcr/ytag514

    PubMed

  8. Smartphone-Based Remote Monitoring for Cardiac Implantable Electronic Devices: Transmission Performance and Early Alert Responsiveness.

    Yanagisawa S, Inden Y, Hibino M, Sato Y, Narita Y, Miyazawa H, Miyamae K, Fukushima T, Hiramatsu T, Adachi K, Teraoka T, Ota R, Tanaka Y, Shimojo M, Tsuji Y, Okumura T, Murohara T

    JACC. Asia   6 巻 ( 7 ) 頁: 1286 - 1289   2026年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacasi.2026.04.028

    PubMed

  9. Optimal Timing for Oral Anticoagulant Discontinuation and Prognosis After Successful Catheter Ablation for Atrial Fibrillation.

    Iwawaki T, Yanagisawa S, Inden Y, Miyamae K, Miyazawa H, Goto T, Kondo S, Tachi M, Fukushima T, Hiramatsu T, Adachi K, Teraoka T, Ota R, Shimojo M, Tsuji Y, Okumura T, Murohara T

    JACC. Clinical electrophysiology   12 巻 ( 7 ) 頁: 1632 - 1647   2026年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2026.02.027

    PubMed

  10. Deep Learning Model for High-Accuracy Classification of Premature Ventricular Contractions With Precordial Transition Zones in Leads V3 or V4.

    Miyamae K, Inden Y, Shimojo M, Miyazawa H, Iwawaki T, Tachi M, Kondo S, Goto T, Yanagisawa S, Tsuji Y, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   90 巻 ( 7 ) 頁: 773 - 782   2026年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.CJ-25-0534

    PubMed

  11. Long-Term Prognosis and Outcomes in Patients Undergoing His Bundle Pacing Implantation - A Multicenter, Prospective Observational Study in Japan.

    Yanagisawa S, Kato H, Kanzaki Y, Murase Y, Fujita M, Nakagomi T, Ishikawa S, Kamikubo Y, Suzuki H, Murakami H, Morishima I, Imai H, Kaneko S, Yoshida Y, Okumura T, Shibata R, Inden Y, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   90 巻 ( 7 ) 頁: 871 - 880   2026年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.CJ-26-0196

    PubMed

  12. Successful Sealing of Steam Pop-Related Left Ventricular Summit Perforation With Partial Impella Support.

    Miyazawa H, Inden Y, Shimojo M, Yanagisawa S, Kazama S, Kondo T, Morimoto R, Yoshizumi T, Mutsuga M, Murohara T

    JACC. Case reports   31 巻 ( 24 ) 頁: 108340   2026年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jaccas.2026.108340

    PubMed

  13. Prospective observational study of the effect of catheter ablation among patients with heart failure with preserved ejection fraction and persistent atrial fibrillation: Findings from BENEFIT-HFpEF.

    Oishi H, Kondo T, Ito R, Kazama S, Haga T, Murase Y, Yamaguchi S, Furui K, Kaneko S, Imai H, Takemoto K, Kobayashi K, Kato T, Suzuki H, Imaizumi T, Hiraiwa H, Morimoto R, Shimojo M, Yanagisawa S, Inden Y, Murohara T

    Heart and vessels     2026年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-026-02716-w

    PubMed

  14. Evaluation of Participant Characteristics and Short-Term Outcomes in a Community-Based Hypertension Awareness Event in Japan.

    Taguchi N, Yanagisawa S, Tsunekawa K, Ota R, Suzuki M, Miyagawa E, Miyahara H, Takemoto S, Murohara T

    International heart journal   67 巻 ( 3 ) 頁: 289 - 291   2026年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1536/ihj.26-054

    PubMed

  15. Efficacy of cardiac resynchronization therapy on cardiac sarcoidosis: Insight into mechanism of mechanical response and the role of myocardial work.

    Kondo S, Inden Y, Yanagisawa S, Miyamae K, Miyazawa H, Goto T, Tachi M, Iwawaki T, Shimojo M, Tsuji Y, Murohara T

    Heart rhythm   23 巻 ( 5 ) 頁: 1187 - 1195   2026年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2025.05.030

    PubMed

  16. Low Perfusion in Heart Failure: The Invisible Half of Hemodynamics at Discharge.

    Okumura T, Hiraiwa H, Yanagisawa S, Murohara T

    Cardiology     頁: 1 - 4   2026年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1159/000551157

    PubMed

  17. Time-course changes in autonomic nervous system activity after pulsed-field ablation for paroxysmal atrial fibrillation: comparison with cryoballoon ablation.

    Fukushima T, Yanagisawa S, Inden Y, Suzuki N, Hiramatsu T, Adachi K, Teraoka T, Ota R, Miyamae K, Miyazawa H, Shimojo M, Tsuji Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     2026年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-026-02321-x

    PubMed

  18. Comparison of left bundle branch area pacing and biventricular pacing for atrioventricular block with heart failure and mild-to-moderately reduced left ventricular systolic function: design and rationale of the BLOCK NAGOYA randomized clinical trial.

    Kato H, Yanagisawa S, Morishima I, Kanzaki Y, Suzuki H, Takasugi N, Sato K, Warita S, Naruse Y, Yokoi K, Ishikawa S, Sugiura S, Mizutani Y, Kamikubo Y, Goto T, Murase Y, Sakamoto Y, Yoshimoto D, Funabiki J, Kuwatsuka Y, Ando M, Okumura T, Inden Y, Murohara T, BLOCK NAGOYA study investigators

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   69 巻 ( 2 ) 頁: 297 - 307   2026年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-025-02210-9

    PubMed

  19. Decreased left ventricular systolic function during the late phase after response to cardiac resynchronization therapy.

    Iwawaki T, Inden Y, Yanagisawa S, Miyamae K, Miyazawa H, Goto T, Kondo S, Tachi M, Shimojo M, Tsuji Y, Murohara T

    Heart rhythm   23 巻 ( 1 ) 頁: 149 - 157   2026年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2025.02.002

    PubMed

  20. Renaissance of Physical Examination in Hemodynamic Heart Failure Assessment.

    Okumura T, Hiraiwa H, Yanagisawa S, Murohara T

    Cardiology   151 巻 ( 3 ) 頁: 322 - 325   2026年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1159/000546543

    PubMed

  21. The Gut-Heart Axis in Heart Failure: Emerging Evidence and Therapeutic Implications.

    Okumura T, Hiraiwa H, Yanagisawa S, Murohara T

    Cardiology   151 巻 ( 3 ) 頁: 326 - 328   2026年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1159/000546542

    PubMed

  22. Cryoballoon Ablation in Older Patients With Heart Failure: Insights From a Large-Scale Multicenter Clinical Study.

    Miyazawa H, Yanagisawa S, Suzuki H, Yoshida Y, Morishima I, Kanzaki Y, Ishikawa S, Kamikubo Y, Kato H, Mizutani Y, Okumura S, Murase Y, Nakasuka K, Warita S, Sekimoto S, Takemoto Y, Takasugi N, Ohguchi S, Senga M, Yokoi K, Ando M, Watanabe R, Ogura Y, Suzuki N, Funabiki J, Shibata R, Inden Y, Murohara T

    JACC. Advances   4 巻 ( 12 Pt 1 ) 頁: 102244   2025年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacadv.2025.102244

    PubMed

  23. Difficult ventilation with suspected laryngospasm in patients undergoing pulsed field ablation for atrial fibrillation under general anesthesia using laryngeal mask airway: A case series.

    Suga K, Kato H, Murakami H, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   11 巻 ( 12 ) 頁: 1271 - 1275   2025年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2025.08.021

    PubMed

  24. Difference in Microembolic Signals Between Flex-Tip Versus Non-Flex-Tip Type Catheters During High-Power Short-Duration Ablation.

    Mizutani Y, Yanagisawa S, Ichikawa M, Nishio K, Sakai H, Nonokawa D, Makino Y, Suzuki H, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Iwawaki T, Kondo S, Yuki Sato, Shibata R, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   36 巻 ( 11 ) 頁: 2919 - 2930   2025年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.70074

    PubMed

  25. Efficacy of Delivery Catheter for the Right Ventricular Septal Placement of a Defibrillator Lead.

    Kato H, Yamazaki K, Sakurai T, Yamazoe S, Tsuzuki K, Suga K, Ota T, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Pacing and clinical electrophysiology : PACE   48 巻 ( 11 ) 頁: 1253 - 1262   2025年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.70060

    PubMed

  26. Selective Left Bundle Branch Capture Using the Uninterrupted Monitoring Technique: Mid-Term Performance and Safety Profile.

    Kato H, Yanagisawa S, Inden Y

    Journal of cardiovascular electrophysiology   36 巻 ( 11 ) 頁: 2849 - 2851   2025年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.70083

    PubMed

  27. Characteristics of Effective Antitachycardia Pacing for Ventricular Tachycardia: The Importance of True Septal Lead Position.

    Yanagisawa S, Inden Y, Sato Y, Watanabe R, Miyazawa H, Miyamae K, Iwawaki T, Goto T, Kondo S, Tachi M, Shimojo M, Tsuji Y, Okumura T, Murohara T

    JACC. Asia   5 巻 ( 10 ) 頁: 1329 - 1343   2025年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacasi.2025.07.005

    PubMed

  28. Plasma proteomics and heart failure: A new frontier beyond ejection fraction.

    Okumura T, Hiraiwa H, Yanagisawa S, Takefuji M, Murohara T

    International journal of cardiology   443 巻   頁: 133943   2025年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijcard.2025.133943

    PubMed

  29. Evaluation of averaged impedance drop percent as a real-time parameter for safe and effective prolonged radiofrequency ablation using the TactiFlex SE catheter: an ex vivo study.

    Suga K, Yamazaki K, Sakurai T, Ota R, Ota T, Kato H, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     2025年8月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-025-02112-w

    PubMed

  30. Benefits of Expert Online Consultations for the Detection of Pulmonary Embolism and Timely Treatment: Enhancing Telemedicine Technology-A Case Report.

    Takenaka M, Yanagisawa S, Yoshida Y, Inden Y, Murohara T

    CJC open   7 巻 ( 8 ) 頁: 1093 - 1096   2025年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.cjco.2025.05.014

    PubMed

  31. Peak frequency drop: a novel intraprocedural parameter predicting acute conduction gaps post-pulmonary vein isolation.

    Mizutani Y, Matsumoto Y, Nishio K, Sakai H, Fujiwara G, Nonokawa D, Makino Y, Suzuki H, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Yanagisawa S, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   68 巻 ( 5 ) 頁: 1035 - 1044   2025年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-025-02019-6

    PubMed

  32. Reply: Side Lobe Artifacts Mimicking False Micro-Perforations.

    Kato H, Yanagisawa S, Shimizu Y, Inden Y, Murohara T

    JACC. Clinical electrophysiology   11 巻 ( 8 ) 頁: 1885 - 1886   2025年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2025.04.032

    PubMed

  33. Reply: Septal Perforation During Left Bundle Branch Pacing: Into the Abyss of the Unknown.

    Kato H, Yanagisawa S, Shimizu Y, Inden Y, Murohara T

    JACC. Clinical electrophysiology   11 巻 ( 8 ) 頁: 1882   2025年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2025.04.024

    PubMed

  34. Char Formation During Very High-Power Short-Duration Ablation for Atrial Fibrillation.

    Suga K, Kato H, Yamazaki K, Sakurai T, Ota R, Ota T, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   36 巻 ( 7 ) 頁: 1569 - 1578   2025年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.16707

    PubMed

  35. Early Left Ventricular Reverse Remodeling After Catheter Ablation of Atrial Fibrillation is Associated With Lower Recurrence Rates and Improved Prognosis in Patients With Left Ventricular Systolic Dysfunction.

    Miyazawa H, Morishima I, Kanzaki Y, Morita Y, Watanabe N, Furui K, Yoshioka N, Shibata N, Arao Y, Yamauchi R, Iwawaki T, Ohi T, Karasawa H, Yanagisawa S, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   36 巻 ( 7 ) 頁: 1548 - 1558   2025年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.16706

    PubMed

  36. Reply to the Editor -Additional value of venous flow pattern for ultrasound-guided venous closure with suture-mediated vascular closure device.

    Tachi M, Tanaka A, Teraoka T, Furuta T, Matsushita E, Hayashi K, Shimojo M, Yanagisawa S, Inden Y, Murohara T

    Heart rhythm   22 巻 ( 7 ) 頁: e259   2025年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2024.11.006

    PubMed

  37. Time-frequency analysis of high-frequency power profile within the QRS complex in patients with ventricular tachycardia using wavelet transform.

    Hiramatsu K, Yanagisawa S, Inden Y, Yamauchi R, Watanabe R, Tsurumi N, Suzuki N, Iwawaki T, Goto T, Kondo S, Tachi M, Shimojo M, Tsuji Y, Murohara T

    Journal of electrocardiology   91 巻   頁: 154027   2025年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jelectrocard.2025.154027

    PubMed

  38. Reply: QS Morphology in a Nonfiltered Unipolar Electrogram From a Left Bundle Branch Pacing Lead.

    Kato H, Yanagisawa S, Shimizu Y, Inden Y, Murohara T

    JACC. Clinical electrophysiology   11 巻 ( 7 ) 頁: 1630   2025年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2025.05.022

    PubMed

  39. A simple technique for manipulating a pentaspline pulsed field ablation catheter to select right inferior pulmonary vein using vertebral body alignment.

    Mizutani Y, Nonokawa D, Kanashiro M, Yanagisawa S, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   68 巻 ( 4 ) 頁: 731 - 733   2025年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-025-01999-9

    PubMed

  40. Clinical Outcomes and Electrophysiological Characteristics of Partial Perforation After Left Bundle Branch Area Pacing.

    Kato H, Yanagisawa S, Shimizu Y, Ota R, Sakurai T, Suga K, Murakami H, Kada K, Tsuboi N, Inden Y, Murohara T

    JACC. Clinical electrophysiology   11 巻 ( 6 ) 頁: 1279 - 1289   2025年6月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2025.01.016

    PubMed

  41. Blood pressure at hospital admission: a window into the prognoses of patients with atrial fibrillation.

    Okumura T, Yanagisawa S, Murohara T

    Hypertension research : official journal of the Japanese Society of Hypertension   48 巻 ( 6 ) 頁: 1985 - 1987   2025年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/s41440-025-02196-x

    PubMed

  42. Global myocardial work index predicts response to biventricular pacing in patients with non-left bundle branch block.

    Kondo S, Inden Y, Yanagisawa S, Miyamae K, Miyazawa H, Goto T, Tachi M, Iwawaki T, Yamauchi R, Hiramatsu K, Shimojo M, Tsuji Y, Murohara T

    ESC heart failure   12 巻 ( 3 ) 頁: 2210 - 2224   2025年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/ehf2.15246

    PubMed

  43. Acute Chest Pain and ST-Segment Changes in a Patient After Permanent His-Bundle Pacing Pacemaker Implantation.

    Yanagisawa S, Inden Y, Tsuji Y, Shibata R, Murohara T

    JACC. Case reports   30 巻 ( 8 ) 頁: 103203   2025年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jaccas.2024.103203

    PubMed

  44. A novel peak frequency mapping algorithm for the precise localization of accessory pathways in the middle cardiac vein: a case report.

    Fujiwara G, Mizutani Y, Yanagisawa S, Inden Y, Murohara T

    European heart journal. Case reports   9 巻 ( 4 ) 頁: ytaf181   2025年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/ehjcr/ytaf181

    PubMed

  45. Pace-mapping guided approach on 3-dimensional imaging predicted the origin of ventricular tachycardia in a non-mirrored dextrocardia patient with counter-clockwise rotation of the cardiac apex: Usefulness of aVR lead for estimation.

    Makino Y, Mizutani Y, Kanashiro M, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   11 巻 ( 4 ) 頁: 287 - 290   2025年4月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2024.12.011

    PubMed

  46. Transmural left atrial roofline block using rescue cryoballoon ablation after unsuccessful radiofrequency ablation.

    Kato H, Yanagisawa S, Suga K, Murakami H, Inden Y, Murohara T

    Heart rhythm O2   6 巻 ( 4 ) 頁: 546 - 550   2025年4月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hroo.2025.01.010

    PubMed

  47. A Practical Scoring System for Estimating Ventricular Arrhythmia Events in Patients with Cardiac Resynchronization Therapy for Primary Prevention.

    Goto T, Inden Y, Yanagisawa S, Tsurumi N, Miyamae K, Miyazawa H, Kondo S, Tachi M, Iwawaki T, Yamauchi R, Hiramatsu K, Shimojo M, Tsuji Y, Murohara T

    International heart journal   66 巻 ( 2 ) 頁: 241 - 251   2025年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1536/ihj.24-646

    PubMed

  48. Discontinuation of Oral Anticoagulation After Successful Atrial Fibrillation Ablation.

    Iwawaki T, Yanagisawa S, Inden Y, Hiramatsu K, Yamauchi R, Miyamae K, Miyazawa H, Goto T, Kondo S, Tachi M, Shimojo M, Tsuji Y, Murohara T

    JAMA network open   8 巻 ( 3 ) 頁: e251320   2025年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1001/jamanetworkopen.2025.1320

    PubMed

  49. Different time course effect of autonomic nervous modulation after cryoballoon and hotballoon catheter ablations for paroxysmal atrial fibrillation.

    Suzuki N, Inden Y, Yanagisawa S, Shimizu Y, Narita S, Hiramatsu K, Yamauchi R, Watanabe R, Tsurumi N, Shimojo M, Suga K, Tsuji Y, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   68 巻 ( 2 ) 頁: 355 - 369   2025年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-023-01581-1

    PubMed

  50. Exploring epicardial arrhythmogenic substrates in long QT syndrome type III overlapping with J-wave syndrome.

    Shimojo M, Inden Y, Yanagisawa S, Tsuji Y, Murohara T

    HeartRhythm case reports   11 巻 ( 3 ) 頁: 256 - 260   2025年3月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2024.12.006

    PubMed

  51. Early catheter ablation: A promising and effective approach for atrial fibrillation and post-heart failure recovery-Timing matters.

    Yanagisawa S, Inden Y, Murohara T

    International journal of cardiology. Heart & vasculature   56 巻   頁: 101604   2025年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijcha.2025.101604

    PubMed

  52. Editorial to "Pre-procedural imaging guiding ventricular tachycardia ablation in structural heart disease".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   41 巻 ( 1 ) 頁: e13211   2025年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13211

    PubMed

  53. Editorial to "Novel mapping techniques for ablation of non-pulmonary vein foci using complex signal identification".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   41 巻 ( 1 ) 頁: e70006   2025年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.70006

    PubMed

  54. Feasibility of left bundle branch area pacing with left axillary pacemaker implantation in a young female patient with heart failure.

    Kato H, Narita Y, Yanagisawa S, Inden Y, Murohara T

    Journal of arrhythmia   41 巻 ( 1 ) 頁: e70022   2025年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.70022

    PubMed

  55. Synthesized V7 QRS Amplitude and Oversensing Episodes in Patients With Subcutaneous Implantable Cardioverter-Defibrillators.

    Okajima T, Ishikawa S, Yanagisawa S, Okamoto T, Uemura Y, Takemoto K, Inden Y, Murohara T, Watarai M

    Pacing and clinical electrophysiology : PACE   47 巻 ( 12 ) 頁: 1565 - 1573   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.15086

    PubMed

  56. An abrupt loss of capture during permanent His-bundle pacing: Assessment of mechanism underlying late capture threshold rise.

    Kato H, Yanagisawa S, Ota R, Inden Y, Murohara T

    Journal of arrhythmia   40 巻 ( 6 ) 頁: 1525 - 1528   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13165

    PubMed

  57. Editorial to "Performance of the novel ANTWERP score in predicting heart function improvement after atrial fibrillation ablation in Asian patients with heart failure".

    Yanagisawa S, Inden Y, Murohara T

    Journal of arrhythmia   40 巻 ( 6 ) 頁: 1370 - 1371   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13173

    PubMed

  58. Editorial to "investigating the role of electroanatomical mapping in single-shot pulsed field catheter ablation".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   40 巻 ( 6 ) 頁: 1379 - 1380   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13184

    PubMed

  59. Do not stop effective atrial-based antitachycardia pacing: Insights into episode duration and success rate for termination.

    Yanagisawa S, Sato Y, Shimizu A, Narita Y, Inden Y, Murohara T

    HeartRhythm case reports   10 巻 ( 12 ) 頁: 867 - 871   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2024.08.016

    PubMed

  60. Differentiation between epicardial and endocardial conduction gaps for left atrial posterior wall isolation using peak frequency annotation algorithm.

    Suga K, Kato H, Murakami H, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   10 巻 ( 12 ) 頁: 912 - 916   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2024.08.028

    PubMed

  61. Identification of regions maintaining atrial fibrillation through cycle length and cycle length gradient mapping.

    Shimojo M, Inden Y, Yanagisawa S, Yamauchi R, Hiramatsu K, Iwawaki T, Tachi M, Kondo S, Goto T, Tsuji Y, Murohara T

    Journal of arrhythmia   40 巻 ( 6 ) 頁: 1389 - 1399   2024年12月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13151

    PubMed

  62. Optimal ablation settings of TactiFlex SE laser-cut irrigated-tip catheter: comparison with ThermoCool SmartTouch SurroundFlow porous irrigated-tip catheter.

    Suga K, Kato H, Akita S, Sakurai T, Ota R, Okada T, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   67 巻 ( 8 ) 頁: 1755 - 1769   2024年11月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-024-01797-9

    PubMed

  63. Early Cryoablation After First Diagnosis of Atrial Fibrillation Reduces Arrhythmia Recurrence in Heart Failure Patients.

    Ando M, Yanagisawa S, Suzuki H, Yoshida Y, Kanzaki Y, Morishima I, Ishikawa S, Kamikubo Y, Okumura S, Kato H, Mizutani Y, Murase Y, Nakasuka K, Warita S, Sekimoto S, Takemoto Y, Takasugi N, Ohguchi S, Senga M, Yokoi K, Watanabe R, Ogura Y, Shibata R, Inden Y, Murohara T

    JACC. Asia   4 巻 ( 11 ) 頁: 857 - 871   2024年11月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacasi.2024.08.005

    PubMed

  64. Feasibility and efficacy of real-time ultrasound-guided venous closure with suture-mediated vascular closure device.

    Tachi M, Tanaka A, Teraoka T, Furuta T, Matsushita E, Hayashi K, Shimojo M, Yanagisawa S, Inden Y, Murohara T

    Heart rhythm   21 巻 ( 10 ) 頁: 2028 - 2036   2024年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2024.04.041

    PubMed

  65. A Novel Liver Fibrosis Marker FIB-5 Index Predicted Response to Cardiac Resynchronization Therapy and Prognostic Outcomes in Patients With Heart Failure. 査読有り

    Iwawaki T, Inden Y, Yanagisawa S, Goto T, Kondo S, Tachi M, Hiramatsu K, Yamauchi R, Shimojo M, Tsuji Y, Murohara T

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc   29 巻 ( 5 ) 頁: e70004   2024年9月

     詳細を見る

    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/anec.70004

    PubMed

  66. Reversible complete left bundle branch block and a wide QRS complex following administration of sodium-glucose cotransporter-2 inhibitor and volume reduction in a patient with systolic heart failure: a case report.

    Takenaka M, Yanagisawa S, Yoshida Y, Inden Y, Murohara T

    European heart journal. Case reports   8 巻 ( 9 ) 頁: ytae512   2024年9月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/ehjcr/ytae512

    PubMed

  67. Long-Term Outcomes in Patients With Relatively High His-Bundle Capture Threshold After Permanent His-Bundle Pacing - A Multicenter Clinical Study. 査読有り Open Access

    Watanabe R, Kato H, Yanagisawa S, Sakurai T, Ota R, Murakami H, Kada K, Tsuboi N, Inden Y, Shibata R, Murohara T

    Circulation reports   6 巻 ( 8 ) 頁: 294 - 302   2024年8月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circrep.CR-24-0035

    Open Access

    PubMed

  68. Elevated liver fibrosis-4 index predicts recurrence after catheter ablation for atrial fibrillation in patients with heart failure.

    Iwawaki T, Morishima I, Kanzaki Y, Morita Y, Watanabe N, Yoshioka N, Shibata N, Miyazawa H, Shimojo K, Yanagisawa S, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   67 巻 ( 5 ) 頁: 1093 - 1108   2024年8月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-023-01661-2

    PubMed

  69. Editorial to "Notched P-wave on digital electrocardiogram predicts the recurrence of atrial fibrillation in patients who have undergone catheter ablation".

    Yanagisawa S, Inden Y, Murohara T

    Journal of arrhythmia   40 巻 ( 4 ) 頁: 790 - 791   2024年8月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13067

    PubMed

  70. Evaluation of microembolic signals on carotid ultrasound during pulmonary vein isolation with high-power short-duration and cryoballoon ablations: When and where do bubble and solid emboli arise?

    Mizutani Y, Yanagisawa S, Ichikawa M, Nishio K, Sakai H, Nonokawa D, Makino Y, Suzuki H, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   35 巻 ( 8 ) 頁: 1589 - 1600   2024年8月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.16337

    PubMed

  71. Mid-term outcomes of delivery catheter-based and stylet-based right ventricular septal pacing: Follow-up results from a multicenter, prospective, randomized study. 査読有り

    Tsurumi N, Naruse Y, Kurebayashi N, Morikawa S, Sano M, Shiozawa T, Takano S, Ogano M, Kimura K, Miyajima K, Sugiura R, Henmi R, Muto M, Hosoya N, Hasebe H, Mizukami A, Iguchi K, Atsumi A, Odagiri K, Yanagisawa S, Inden Y, Murohara T, Maekawa Y

    Journal of arrhythmia   40 巻 ( 3 ) 頁: 605 - 613   2024年6月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.13034

    PubMed

  72. Coagulation Profile After Catheter Ablation for Ventricular Tachycardia in Antiplatelet and Anticoagulant Regimens. 査読有り

    Yanagisawa S, Inden Y, Iwawaki T, Tachi M, Hiramatsu K, Yamauchi R, Shimojo M, Tsuji Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   10 巻 ( 5 ) 頁: 976 - 978   2024年5月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2024.02.013

    PubMed

  73. Comparison of novel intrinsic versus conventional antitachycardia pacing for ventricular tachycardia among implantable cardioverter-defibrillator recipients.

    Yanagisawa S, Inden Y, Sato Y, Watanabe R, Goto T, Kondo S, Tachi M, Iwawaki T, Yamauchi R, Hiramatsu K, Shimojo M, Tsuji Y, Shibata R, Murohara T

    Journal of cardiovascular electrophysiology   35 巻 ( 4 ) 頁: 821 - 831   2024年4月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.16232

    PubMed

  74. Development of a rapid and comprehensive genomic profiling test supporting diagnosis and research for gliomas.

    Nakashima T, Yamamoto R, Ohno M, Sugino H, Takahashi M, Funakoshi Y, Nambu S, Uneda A, Yanagisawa S, Uzuka T, Arakawa Y, Hanaya R, Ishida J, Yoshimoto K, Saito R, Narita Y, Suzuki H

    Brain tumor pathology   41 巻 ( 2 ) 頁: 50 - 60   2024年4月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10014-023-00476-3

    PubMed

  75. Distributions and number of drivers on real-time phase mapping associated with successful atrial fibrillation termination during catheter ablation for non-paroxysmal atrial fibrillation. 査読有り

    Riku S, Inden Y, Yanagisawa S, Fujii A, Tomomatsu T, Nakagomi T, Shimojo M, Okajima T, Furui K, Suga K, Suzuki S, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   67 巻 ( 2 ) 頁: 303 - 317   2024年3月

     詳細を見る

    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-023-01588-8

    PubMed

  76. Reply: Methodological and Mechanistic Considerations in Local Repolarization Mapping.

    Yanagisawa S, Inden Y, Tsuji Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   10 巻 ( 2 ) 頁: 378   2024年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2024.01.009

    PubMed

  77. Editorial to "pseudo-slow-fast atrioventricular nodal reentrant tachycardia: Is the fast pathway a criminal or innocent bystander?".

    Mizutani Y, Yanagisawa S, Inden Y

    Journal of arrhythmia   40 巻 ( 1 ) 頁: 146 - 147   2024年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/joa3.12978

    PubMed

  78. Usefulness of omnipolar technology near field for accessory pathway ablation through the coronary sinus.

    Mizutani Y, Yanagisawa S, Matsumoto Y, Kanashiro M, Inden Y, Murohara T

    HeartRhythm case reports   10 巻 ( 1 ) 頁: 92 - 95   2024年1月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2023.10.030

    PubMed

  79. Clinical outcomes and predictors of delayed echocardiographic response to cardiac resynchronization therapy.

    Tsurumi N, Inden Y, Yanagisawa S, Hiramatsu K, Yamauchi R, Watanabe R, Suzuki N, Shimojo M, Suga K, Tsuji Y, Murohara T

    Journal of cardiovascular electrophysiology   35 巻 ( 1 ) 頁: 97 - 110   2024年1月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.16125

    PubMed

  80. Mechanisms of torsades de pointes: an update. 査読有り

    Tsuji Y, Yamazaki M, Shimojo M, Yanagisawa S, Inden Y, Murohara T

    Frontiers in cardiovascular medicine   11 巻   頁: 1363848   2024年

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3389/fcvm.2024.1363848

    PubMed

  81. Association Between Catheter Ablation for Nonparoxysmal Atrial Fibrillation and Functional Mitral Regurgitation in Patients With Heart Failure With Preserved Ejection Fraction.

    Yamauchi R, Morishima I, Okumura K, Kanzaki Y, Morita Y, Watanabe N, Furui K, Yoshioka N, Shibata N, Miyazawa H, Shimojo K, Imaoka T, Sakamoto G, Goto H, Ohi T, Yanagisawa S, Inden Y, Murohara T

    The American journal of cardiology   207 巻   頁: 192 - 201   2023年11月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.amjcard.2023.08.154

    PubMed

  82. Visualization of Repolarization Heterogeneity in Brugada Syndrome: A Quantitative Analysis of Unipolar Electrogram T-Wave. 査読有り Open Access

    Yanagisawa S, Inden Y, Goto T, Kondo S, Tachi M, Iwawaki T, Hiramatsu K, Yamauchi R, Shimojo M, Tsuji Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   9 巻 ( 11 ) 頁: 2401 - 2411   2023年11月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2023.08.010

    Open Access

    PubMed

  83. Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads. 査読有り Open Access

    Perino AC, Wang PJ, Lloyd M, Zanon F, Fujiu K, Osman F, Briongos-Figuero S, Sato T, Aksu T, Jastrzebski M, Sideris S, Rao P, Boczar K, Yuan-Ning X, Wu M, Namboodiri N, Garcia R, Kataria V, De Pooter J, Przibille O, Gehi AK, Cano O, Katsouras G, Cai B, Astheimer K, Tanawuttiwat T, Datino T, Rizkallah J, Alasti M, Feld G, Barrio-Lopez MT, Gilmore M, Conti S, Yanagisawa S, Indik JH, Zou J, Saha SA, Rodriguez-Munoz D, Chang KC, Lebedev DS, Leal MA, Haeberlin A, Forno ARJD, Orlov M, Frutos M, Cabanas-Grandio P, Lyne J, Leyva F, Tolosana JM, Ollitrault P, Vergara P, Balla C, Devabhaktuni SR, Forleo G, Letsas KP, Verma A, Moak JP, Shelke AB, Curila K, Cronin EM, Futyma P, Wan EY, Lazzerini PE, Bisbal F, Casella M, Turitto G, Rosenthal L, Bunch TJ, Baszko A, Clementy N, Cha YM, Chen HC, Galand V, Schaller R, Jarman JWE, Harada M, Wei Y, Kusano K, Schmidt C, Hurtado MAA, Naksuk N, Hoshiyama T, Kancharla K, Iida Y, Mizobuchi M, Morin DP, Cay S, Paglino G, Dahme T, Agarwal S, Vijayaraman P, Sharma PS

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   66 巻 ( 7 ) 頁: 1589 - 1600   2023年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-022-01417-4

    PubMed

  84. Subclinical persistent atrial fibrillation in left atrium behind the ectopic atrial rhythm on electrocardiogram.

    Mizutani Y, Yanagisawa S, Makino Y, Kanashiro M, Inden Y, Murohara T

    HeartRhythm case reports   9 巻 ( 9 ) 頁: 685 - 688   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2023.07.005

    PubMed

  85. Evaluation of the direction and extent of ice formation during cryoballoon ablation: an experimental study.

    Mizutani Y, Yanagisawa S, Fujiwara G, Kasai Y, Tajima A, Makino Y, Suzuki H, Hiramatsu T, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Inden Y, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   66 巻 ( 4 ) 頁: 981 - 989   2023年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Interventional Cardiac Electrophysiology  

    Background: The distal hemisphere of a balloon is generally cooled during cryoapplication. However, a wide ablation area can be acquired after cryoballoon ablation. This study aimed to evaluate the extent of ice formation on two types of balloon surfaces through experimental and simulation studies. Methods: A standard cryoballoon (SCB; Arctic Front Advance Pro, Medtronic) and novel cryoballoon (NCB; POLARx, Boston Scientific) were frozen for 240 s in 36 °C normal saline solution to observe ice formation on the balloon surface. Pieces of porcine tissue were placed between the upper and lower sides of the balloon, and the balloon was frozen in the horizontal direction for 240 s in 20 attempts (10 for SCB and NCB each). The measured areas of ice formation were evaluated and compared between the upper and lower sides of each balloon. Results: Ice formation was greater on the lower side of the balloon than on the upper side. A larger area of ice formation in the tissue slab was observed on the lower side than on the upper side in both balloons, and the ice formation extended to the proximal hemisphere on the lower side of the balloon. The ice formation area in the NCB was significantly larger than that in SCB. Conclusions: Ice formation was significantly greater on the lower side of the cryoballoon than on the upper side and extended to the proximal hemisphere of the balloon, which might facilitate the acquisition of a wide ablation area on the left atrial posterior wall after cryoballoon ablation. Graphical Abstract: Different ice formation after cryoballoon ablation Greater ice formation on the lower side of cryoballoon and an extensive ice formation in the proximal hemisphere, especially in novel cryoballoon. [Figure not available: see fulltext.]

    DOI: 10.1007/s10840-022-01411-w

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  86. Transmural lesion formation after left atrial roof cryoballoon ablation: Insight from simultaneous high-density epicardial mapping. Open Access

    Kato H, Yanagisawa S, Sakurai T, Murakami H, Inden Y, Murohara T

    Heart rhythm O2   4 巻 ( 5 ) 頁: 329 - 332   2023年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hroo.2023.02.004

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  87. Successful catheter ablation for a dominant atrial fibrillation driver manifested after box isolation using a novel mapping system in a patient with persistent atrial fibrillation.

    Tachi M, Teraoka T, Hayashi K, Yanagisawa S, Inden Y, Murohara T

    HeartRhythm case reports   9 巻 ( 5 ) 頁: 319 - 323   2023年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrcr.2023.02.010

    PubMed

  88. Catheter ablation for atrial fibrillation in heart failure: Getting closer to the full picture in the whole population.

    Yanagisawa S, Inden Y, Murohara T

    International journal of cardiology   376 巻   頁: 81 - 82   2023年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijcard.2023.02.010

    PubMed

  89. A rare case of delayed complete lead dislodgement after deep septal pacing: A hidden risk of the specific procedure.

    Watanabe R, Inden Y, Yanagisawa S, Narita Y, Hiramatsu K, Yamauchi R, Tsurumi N, Suzuki N, Shimojo M, Suga K, Tsuji Y, Murohara T

    Pacing and clinical electrophysiology : PACE   46 巻 ( 4 ) 頁: 341 - 345   2023年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.14688

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  90. A novel practical algorithm using machine learning to differentiate outflow tract ventricular arrhythmia origins. Open Access

    Shimojo M, Inden Y, Yanagisawa S, Suzuki N, Tsurumi N, Watanabe R, Nakagomi T, Okajima T, Suga K, Tsuji Y, Murohara T

    Journal of cardiovascular electrophysiology   34 巻 ( 3 ) 頁: 627 - 637   2023年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.15823

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  91. Efficacy and feasibility of cryoballoon ablation for atrial fibrillation in patients with heart failure: A large-scale multicenter study.

    Yanagisawa S, Suzuki H, Kanzaki Y, Ishikawa S, Kamikubo Y, Okumura S, Kato H, Mizutani Y, Murase Y, Nakasuka K, Warita S, Sekimoto S, Takemoto Y, Takasugi N, Ohguchi S, Senga M, Yokoi K, Shibata R, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   33 巻 ( 12 ) 頁: 2447 - 2464   2022年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Cardiovascular Electrophysiology  

    Introduction: Data are limited regarding outcomes of cryoballoon ablation for atrial fibrillation (AF) in patients with heart failure (HF). This large-scale multicenter study aimed to evaluate the prognosis of patients with HF after cryoballoon ablation for AF. Methods: Among 3655 patients undergoing cryoballoon ablation at 17 institutions, 549 patients (15%) (391 with paroxysmal AF and 158 with persistent AF) diagnosed with HF preoperatively were analyzed. Clinical endpoints were recurrence, mortality, and HF hospitalization after ablation. Results: Most patients had a preserved left ventricular ejection fraction (LVEF) ≥ 50%. During a mean follow-up period of 25.7 months, recurrence, all-cause death, and HF hospitalization occurred in 29%, 4.0%, and 4.8%, respectively. Cardiac function on echocardiography and B-type natriuretic peptide (BNP) levels significantly improved postoperatively, and the effect was more pronounced in the nonrecurrence group. Major complications occurred in 33 patients (6.0%), but most complications were phrenic nerve palsy (3.6%). Although death and HF hospitalization occurred more frequently in patients with LVEF ≤ 40% (n = 73) and New York Heart Association (NYHA) class III–IV (n = 19) than other subgroups, the BNP levels, and LVEF significantly improved after ablation in all LVEF and NYHA class subgroups. High BNP levels, NHYA class, CHADS2 score, and structural heart disease, but not postablation recurrence, independently predicted death, and HF hospitalization on multivariate analysis. The patients with tachycardia-induced cardiomyopathy had better recovery of BNP levels and LVEF after ablation than those with structural heart disease. Conclusions: Cryoballoon ablation for AF in HF patients is feasible and leads to significantly improved cardiac function.

    DOI: 10.1111/jce.15691

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  92. A case of successful catheter ablation of blocked atrial bigeminy and bradycardia with the recovery of normal sinus rhythm and myocardial reverse remodeling. Open Access

    Sugiyama T, Mizutani Y, Yanagisawa S, Kanashiro M, Inden Y, Murohara T

    Clinical case reports   10 巻 ( 12 ) 頁: e6791   2022年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/ccr3.6791

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  93. Regional left atrial conduction velocity in the anterior wall is associated with clinical recurrence of atrial fibrillation after catheter ablation: efficacy in combination with the ipsilateral low voltage area. 査読有り Open Access

    Ohguchi S, Inden Y, Yanagisawa S, Fujita R, Yasuda K, Katagiri K, Oguri M, Murohara T

    BMC cardiovascular disorders   22 巻 ( 1 ) 頁: 457   2022年11月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Cardiovascular Disorders  

    Background: Left atrial (LA) conduction velocity (CV) is an electrical remodeling parameter of atrial fibrillation (AF) substrate. However, the pathophysiological substrate of LA-CV and its impact on outcomes after catheter ablation for AF have not been well evaluated. Methods: We retrospectively evaluated 119 patients with AF who underwent catheter ablation and electroanatomical mapping during sinus rhythm. To measure regional LA-CV, we took triplet sites (A, B, and C) on the activation map and calculated the magnitude of the matched orthogonal projection vector between vector-AB and vector-AC, indicating two-dimensional CV. The median of the LA-CVs from four triad sites in both the anterior and posterior walls was set as the ‘model LA-CV’. We evaluated the impact of the model LA-CV on recurrence after ablation and relationship between the model LA-CV and LA-low voltage area (LVA) of < 0.5 mV. Results: During the 12-month follow-up, 29 patients experienced recurrence. The LA-CV model was significantly correlated with ipsilateral LVA. The lower anterior model LA-CV was significantly associated with recurrence, with the cut-off value of 0.80 m/s having a sensitivity of 72% and specificity of 67%. Multivariable analysis revealed that the anterior model LA-CV (hazard ratio, 0.09; 95% confidence interval, 0.01–0.94; p = 0.043) and anterior LA-LVA (hazard ratio, 1.06; 95% confidence interval, 1.00–1.11; p = 0.033) were independently associated with AF recurrence. The anterior LA-LVA was mildly correlated with the anterior model LA-CV (r = -0.358; p < 0.001), and patients with both lower LA-CV and greater anterior LA-LVA based on each cut-off value had the worst prognosis. However, decreased LA-CV was more likely to be affected by the distribution pattern of the LVA rather than the total size of the LVA. Conclusion: Decreased anterior LA-CV was a significant predictor of AF recurrence and was a useful electrical parameter in addition to LA-LVA for estimating AF arrhythmogenicity.

    DOI: 10.1186/s12872-022-02881-6

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  94. Septal coronary artery fistula after left bundle branch area pacing assessed by multi-imaging modalities and shunt volume quantification.

    Kato H, Yanagisawa S, Ota R, Murakami H, Kada K, Tsuboi N, Inden Y, Murohara T

    Pacing and clinical electrophysiology : PACE   45 巻 ( 11 ) 頁: 1299 - 1302   2022年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.14548

    PubMed

  95. Impact of synchronized left ventricular pacing rate on risk for ventricular tachyarrhythmias after cardiac resynchronization therapy in patients with heart failure. 査読有り

    Okajima T, Inden Y, Yanagisawa S, Suga K, Shimojo M, Nakagomi T, Tsurumi N, Watanabe R, Suzuki N, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   65 巻 ( 1 ) 頁: 239 - 249   2022年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Interventional Cardiac Electrophysiology  

    Background: The adaptive cardiac resynchronization therapy (aCRT) algorithm automatically produces synchronized left ventricular pacing (sLVP) with intrinsic atrioventricular conduction to improve clinical outcomes. However, relationship between sLVP percentage and risk for ventricular tachyarrhythmia (VT/VF) remains unclear. This study aimed to evaluate the clinical impact of sLVP rate on VT/VF occurrence. Methods: In total, 1,419 device interrogation data from 42 consecutive patients who underwent new aCRT device implantation were retrospectively analyzed. The primary endpoint was the first time VT/VF episode after aCRT device implantation. Results: During a median follow-up of 34 months, 15 patients had VT/VF episodes. Patients were divided into a high sLVP (the average sLVP percentage of ≥ 51.5%, n = 27) or low sLVP group (< 51.5%, n = 15). The high sLVP group had a significantly lower VT/VF incidence (22% vs. 60%; p = 0.014) and an independent predictor for VT/VF occurrence on multivariate analysis (hazard ratio 0.21; p = 0.007). LV ejection fraction improvements after 6 months (12.3 ± 8.7% vs. 2.8 ± 10.3%; p = 0.004) and 12 months (13.8 ± 9.3% vs. 6.2 ± 11.1%; p = 0.030) were significantly greater in the high sLVP group than in the low sLVP group. Age, PR interval, and left atrial diameter were significantly associated with the sLVP rate after aCRT. Conclusions: Patients with high sLVP percentage after aCRT had lower long-term risk of VT/VF incidence with a favorable response to CRT. A synchronized pacing algorithm using intrinsic conduction may prevent malignant arrhythmias, as well as recover cardiac functions.

    DOI: 10.1007/s10840-022-01284-z

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  96. Depolarization and repolarization dynamics after His-bundle pacing: Comparison with right ventricular pacing and native ventricular conduction. 査読有り Open Access

    Yanagisawa S, Inden Y, Watanabe R, Tsurumi N, Suzuki N, Nakagomi T, Shimojo M, Okajima T, Riku S, Furui K, Suga K, Shibata R, Murohara T

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc   27 巻 ( 5 ) 頁: e12991   2022年9月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Annals of Noninvasive Electrocardiology  

    Background: The current study aimed to evaluate changes in electrical depolarization and repolarization parameters after His-bundle pacing (HBP) compared with right ventricular pacing (RVP) and its association with ventricular arrhythmia (VA). Methods: Forty-one patients (13 with HBP, 14 with RVP, and 14 controls [AAI mode]) were evaluated. After continuous pacing algorithm, QRS duration, QT interval, QTc, JT interval, T-peak to T-end (Tpe), and Tpe/QT ratio were measured on electrocardiography at baseline and 1 week, 1 month, and 6 months postoperatively. We investigated VA occurrence and adverse events after implantation. Results: At 6 months, QRS duration was significantly shorter in the HBP (121.6 ± 15.6 ms) than in the RVP (150.1 ± 14.9 ms) group. The QT intervals were lower in the HBP (424.0 ± 40.9 ms) and control (405.9 ± 23.0 ms) groups than in the RVP (453.0 ± 40.2 ms) group. The Tpe and Tpe/QT ratios at 6 months differed significantly between the HBP and RVP groups (Tpe, 69.8 ± 19.7 ms vs 87.4 ± 11.9 ms and Tpe/QT, 0.16 ± 0.03 vs 0.19 ± 0.02, respectively). The Tpe and Tpe/QT ratios were similarly shortened in the HBP and control groups. VA occurred less frequently in the HBP (15%) and control (7.1%) groups than in the RVP (50%) group (p = 0.020). The non-RVP group showed significantly lower rates of VA and major adverse events than the RVP group. Patients with VA demonstrated significantly longer QRS duration, QT interval, Tpe, and Tpe/QT at 6 months than those without VA. Conclusion: HBP showed better depolarization and repolarization stability than RVP.

    DOI: 10.1111/anec.12991

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  97. Characteristics of successful reactive atrial-based antitachycardia pacing in patients with cardiac implantable electronic devices: History of catheter ablation of atrial fibrillation as a predictor of high treatment efficacy.

    Nakagomi T, Inden Y, Yanagisawa S, Suzuki N, Tsurumi N, Watanabe R, Shimojo M, Okajima T, Suga K, Shibata R, Murohara T

    Journal of cardiovascular electrophysiology   33 巻 ( 7 ) 頁: 1515 - 1528   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Cardiovascular Electrophysiology  

    Introduction: Reactive atrial-based antitachycardia pacing (rATP) in patients with cardiac implantable electronic devices (CIEDs) suppresses the progression of atrial fibrillation (AF) to the persistent form. However, the clinical factors associated with successful reactive atrial-based antitachycardia pacing (rATP) treatment are unknown. This study aimed to examine the predictors of high rATP efficacy in patients with CIEDs. Methods: The data of 101,325 rATP-treated atrial tachyarrhythmia (AT/AF) episodes in 51 patients, obtained through remote monitoring and device interrogation, were analyzed. The study population was divided into the high and low efficacy groups based on the overall median success rate of rATP. Clinical characteristics were compared between the two groups. Results: During a follow-up period of 28.6 ± 8.6 months, the median success rate was 43.7% (31.5%–64.9%). The prevalence of a history of catheter ablation of AF was significantly higher in the high efficacy group than in the low efficacy group (73.0% vs. 44.0%, p =.048) and was the only independent predictor of high rATP efficacy (odds ratio, 3.45; p =.038). The rATP success rate in patients with (n = 30) and without (n = 21) a history of catheter ablation was 53.9% (40.0%–67.5%) and 36.4% (22.2%–47.7%), respectively (p =.012). The effect of rATP after ablation was more pronounced in patients with long cycle length episodes (≥75% of AT/AF sequences having a cycle length of 200–449 ms) (67.3% [46.0%–73.6%] vs. 30.6% [18.1%–60.3%], p =.027). The high efficacy group had a significantly lower incidence of AT/AF lasting ≥1, ≥7, and ≥30 days than the low efficacy group. Conclusion: rATP combined with catheter ablation therapy is effective in suppressing AT/AF.

    DOI: 10.1111/jce.15551

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  98. Coagulation Response and Prothrombotic Effect of Uninterrupted Oral Anticoagulant Administration After Catheter Ablation for VT. 査読有り

    Yanagisawa S, Inden Y, Riku S, Furui K, Suga K, Nakagomi T, Shimojo M, Okajima T, Watanabe R, Tsurumi N, Suzuki N, Shibata R, Murohara T

    JACC. Clinical electrophysiology   8 巻 ( 6 ) 頁: 735 - 748   2022年6月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JACC: Clinical Electrophysiology  

    Background: Catheter ablation for ventricular tachycardia (VT) is associated with perioperative thromboembolic risk. However, the strategy for postprocedural management remains unknown. Objectives: The aim of this study was to evaluate the prothrombotic response after VT ablation in various coagulation biomarkers in patients with and without the administration of oral anticoagulation (OAC). Methods: Data from 112 patients (58 with uninterrupted OAC and 54 without) with structural heart disease who underwent endocardial VT ablation were retrospectively analyzed. We also included 41 patients who underwent ablation for premature ventricular contraction from the right ventricle and 13 patients who underwent electrophysiology study (the control group). Blood samples of coagulation markers were collected before and 3 days after the procedure in all patients. Results: The percentage of D-dimer levels ≤1.0 μg/mL at baseline was lower in the VT ablation groups (76% and 50% in the OAC and non-OAC groups, respectively) than in the other groups (100%). After 3 days, the percentage remained at 67% in the OAC group; however, the non-OAC VT group demonstrated a remarkable decrease of 20%. Similarly, fibrin monomer complex, thrombin antithrombin, and prothrombin fragment 1+2 levels were well suppressed in the control, premature ventricular contraction, and OAC groups. However, the non-OAC group demonstrated increased coagulation markers both before and after 3 days. Multivariate analysis demonstrated that OAC administration and normal coagulation markers at baseline were independent predictors of stable coagulation status after ablation. Conclusions: The coagulation cascade was significantly activated in patients undergoing VT ablation. Uninterrupted OAC administration suppressed the coagulation response, which might be associated with a reduction in perioperative prothrombotic risk.

    DOI: 10.1016/j.jacep.2022.02.015

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  99. Cryoballoon ablation for atrial fibrillation without the use of a contrast medium: a combination of the intracardiac echocardiography and pressure wave monitoring guided approach.

    Makino Y, Mizutani Y, Yamashita D, Yonekawa J, Satake A, Kurobe M, Hiramatsu T, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Ichimiya S, Yanagisawa S, Inden Y, Murohara T

    Heart and vessels   37 巻 ( 5 ) 頁: 765 - 774   2022年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-021-01963-3

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  100. Short coupling interval with high burden of atrial ectopy predicts recurrence after atrial fibrillation ablation.

    Okajima T, Inden Y, Yanagisawa S, Imai H, Murase Y, Ogawa Y, Kawaguchi K, Murohara T

    Heart and vessels   37 巻 ( 5 ) 頁: 775 - 787   2022年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-021-01966-0

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  101. Identification of high priority focal activations in persistent atrial fibrillation using a novel mapping strategy.

    Shimojo M, Inden Y, Yanagisawa S, Riku S, Suga K, Furui K, Nakagomi T, Okajima T, Shibata R, Murohara T

    Heart and vessels   37 巻 ( 5 ) 頁: 840 - 853   2022年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-021-01977-x

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  102. Long P-wave duration immediately after pulmonary vein isolation on radiofrequency catheter ablation for atrial fibrillation predicts clinical recurrence: correlation with atrial remodeling in persistent atrial fibrillation.

    Ohguchi S, Inden Y, Yanagisawa S, Shigematsu T, Yasuda K, Katagiri K, Oguri M, Murohara T

    Heart and vessels   37 巻 ( 3 ) 頁: 476 - 488   2022年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    © 2021, Springer Japan KK, part of Springer Nature. P-wave morphology reflects atrial remodeling and indicates prognosis after radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF). The impact of p-wave morphology after excluding the effect of pulmonary vein (PV) substrate on outcomes is unknown. We evaluated the p-wave morphology on electrocardiography immediately after PV isolation for clinical outcomes. Eighty-four consecutive patients (47 with paroxysmal AF and 37 with persistent AF) who underwent RFCA were included. P-wave duration (PWD) and amplitude in all leads were examined during sinus rhythm immediately after PV isolation. We evaluated the relationship between electrocardiogram parameters and AF recurrence, according to the type of AF and following ablation, and the correlation with left atrial (LA) volume, low voltage ratio, and fixed conduction time. During 12 months of follow-up, 20 patients experienced recurrence. The cut-off value of PWD > 120 ms in lead I showed a sensitivity of 75% and specificity of 69% for predicting recurrence. PWD was significantly correlated with LA volume, low voltage, and conduction velocity. Significantly higher recurrence rates were observed in patients with PWD > 120 ms than in those with PWD ≤ 120 ms (p < 0.001), and the difference was more pronounced in patients with persistent AF. Multivariate analysis demonstrated that PWD > 120 ms was independently associated with recurrence in the total population (hazard ratio 2.00; 95% confidence interval 1.27–3.22; p = 0.003) and in patients with persistent AF. In conclusion, long PWD after PV isolation predicts AF recurrence, which might be associated with the extent of the LA substrate in persistent AF.

    DOI: 10.1007/s00380-021-01932-w

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  103. Impact of Preoperative Nutritional Status on the Outcome of Catheter Ablation for Atrial Fibrillation. Open Access

    Furui K, Morishima I, Morita Y, Kanzaki Y, Takagi K, Nagai H, Watanabe N, Yoshioka N, Yamauchi R, Miyazawa H, Yanagisawa S, Inden Y, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   86 巻 ( 2 ) 頁: 268 - 276   2022年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.CJ-21-0218

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  104. Comparison of the empirical linear ablation and low voltage area-guided ablation in addition to pulmonary vein isolation in patients with persistent atrial fibrillation: a propensity score-matched analysis. 査読有り Open Access

    Suzuki N, Kaneko S, Fujita M, Shinoda M, Kubota R, Ohashi T, Tatami Y, Suzuki J, Hori H, Adachi K, Ito R, Shirai Y, Yanagisawa S, Inden Y, Murohara T

    BMC cardiovascular disorders   22 巻 ( 1 ) 頁: 13   2022年1月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Cardiovascular Disorders  

    Background: The efficacy of pulmonary vein isolation (PVI) alone is not guaranteed for persistent atrial fibrillation (PeAF), and it is unclear which type of ablation approach should be applied in addition to PVI. This study aimed to compare outcomes and prognosis between empirical linear ablation and low-voltage area (LVA) ablation after PVI for PeAF. Methods: We enrolled 128 patients with PeAF who were assigned to the linear ablation group (n = 64) and the LVA ablation group (n = 64) using a propensity score-matched model. After PVI and cardioversion, the patients underwent either empirical linear ablation or LVA ablation during sinus rhythm. All patients in the linear ablation group underwent both roof line and mitral valve isthmus (MVI) ablations. An electrical-guided ablation targeting LVA (< 0.5 mV) was performed in the LVA group. When there was no LVA in the LVA group, only PVI was applied. We compared the procedural outcomes and recurrence after ablation between the two groups. Results: The baseline characteristics were well-balanced between the two groups. Fifty patients had LVA (22 and 28 patients in the linear and LVA groups). The roof and MVI lines were completed in 100% and 96.9% of the patients. During the mean follow-up of 279.5 ± 161.3 days, the LVA group had significantly lower recurrence than the linear group (15 patients [23%] vs. 29 patients [45%], p = 0.014). Thirty-five patients were prescribed antiarrhythmic drugs during the follow-up period (linear group, n = 17; LVA group, n = 18); amiodarone and bepridil were administered to most of the patients (15 and 17 patients, respectively). The difference in the prognosis was relevant among the patients with LVA, while this trend was not observed in those without LVA. The LVA ablation group demonstrated significantly lower radiofrequency energy and shorter procedural time compared to the linear ablation group. The recurrence of atrial flutter was more likely to occur in the linear group than in the LVA group (14 [22%] vs. 6 [9.4%], p = 0.052). Conclusion: The electrophysiological-guided LVA ablation is more effective than empirical linear ablation in PeAF patients with LVA. Unnecessary empirical linear ablation might have a risk of iatrogenic gap and atrial flutter recurrence.

    DOI: 10.1186/s12872-022-02460-9

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  105. Efficacy of His Bundle Pacing on LV Relaxation and Clinical Improvement in HF and LBBB. 査読有り

    Kato H, Yanagisawa S, Sakurai T, Mizuno C, Ota R, Watanabe R, Suga K, Okada T, Murakami H, Kada K, Inden Y, Tsuboi N, Murohara T

    JACC. Clinical electrophysiology   8 巻 ( 1 ) 頁: 59 - 69   2022年1月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JACC: Clinical Electrophysiology  

    Objectives: This study aimed to compare acute hemodynamic improvements and responses to His bundle pacing (HBP) and conventional biventricular pacing (BVP). Background: HBP can correct left bundle branch block (LBBB) and may be an alternative cardiac resynchronization therapy (CRT) to BVP. Methods: Fourteen consecutive patients with heart failure (HF) and typical LBBB who required CRT were enrolled. The acute hemodynamic responses during HBP and BVP were compared using a micromanometer-tipped catheter inserted into the left ventricle (LV) before CRT. Each configuration was compared with AAI mode. A permanent HBP device was implanted when LBBB correction threshold was ≤1.5 V at 1.0 ms, and remaining patients were treated with BVP. Clinical and echocardiographic improvements were assessed during a 12-month follow-up period. Results: The LV contractile index (positive maximal rate of LV pressure rise [dP/dtmax]) increased similarly during HBP and BVP (18.8% ± 6.4% vs 18.0% ± 10.2%; P = 0.810). LV relaxation indices (negative dP/dtmax and tau) were significantly improved during HBP compared with BVP (negative dP/dtmax: 14.3% ± 5.5% vs 3.1% ± 8.1%; P < 0.001; tau: 7.2% ± 4.3% vs −0.8% ± 8.1%; P = 0.001). Nine (64%) patients received permanent HBP devices, while 5 patients were treated with BVP. The New York Heart Association functional class, LV ejection fraction, LV end-systolic volume, and B-type natriuretic peptide level improved in patients treated with HBP and BVP (all P < 0.05 vs baseline). Patients treated with HBP exhibited earlier and greater improvements of the LV ejection fraction and LV end-systolic volume than did those with BVP. Conclusions: HBP improves systolic function and LV relaxation in patients with HF and LBBB. CRT via HBP produced earlier and greater clinical responses than BVP.

    DOI: 10.1016/j.jacep.2021.06.011

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  106. Usefulness of the Snare Technique During Leadless Pacemaker Implantation for a Patient with a Severely Dilated Right Atrium. Open Access

    Hiramatsu T, Mizutani Y, Yanagisawa S, Sugiyama T, Yamashita D, Tajima A, Yonekawa J, Makino Y, Suzuki H, Ichimiya H, Uchida Y, Watanabe J, Kanashiro M, Inden Y, Murohara T

    International heart journal   63 巻 ( 1 ) 頁: 159 - 162   2022年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:International Heart Journal  

    We report here the case of a 92-year-old woman with atrial fibrillation bradycardia in which leadless pacemaker implantation was performed with a difficult delivery of the catheter sheath due to an extremely large right atrium. Using a snare technique with correction of the direction of the force on the catheter toward the right ventricle (RV) can result in successful delivery of the pacemaker catheter and stable placement of the pacemaker system in the RV septum. This specific snare technique has the potential to facilitate leadless pacemaker implantation safely in a severely dilated chamber of the heart, making this technique effective to use in clinical practice.

    DOI: 10.1536/ihj.21-499

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  107. Evaluation of the Novel Automated Anti-Tachycardia Pacing Algorithm Successfully Terminating Sustained Monomorphic Ventricular Tachycardia in an Electrophysiology Study. 査読有り Open Access

    Yanagisawa S, Inden Y, Okajima T, Nakagomi T, Shimojo M, Watanabe R, Tsurumi N, Suzuki N, Suga K, Shibata R, Murohara T

    International heart journal   63 巻 ( 3 ) 頁: 633 - 638   2022年

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:International Heart Journal  

    We report the usefulness of novel automated anti-tachycardia pacing (ATP) for ventricular tachycardia (VT) termination evaluated in an electrophysiology study. This intrinsic, automated ATP with an implanted cardiac resynchronization therapy-defibrillator successfully terminated the sustained VT, which had not been suppressed by repetitive burst pacing from the electrode catheter. The reproduction of programed pacing of the automated ATP by a right ventricular electrode catheter was effective in terminating VT, and this termination was absolute and reproducible. Further detailed assessment in an electrophysiology study could highlight the algorithm of the automated ATP and its possible benefit in terminating the reentrant VT.

    DOI: 10.1536/ihj.21-755

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  108. Earliest pulmonary vein potential-guided cryoballoon ablation is associated with better clinical outcomes than conventional cryoballoon ablation: A result from two randomized clinical studies.

    Mizutani Y, Yanagisawa S, Kanashiro M, Yamashita D, Yonekawa J, Makino Y, Hiramatsu T, Ichimiya H, Uchida Y, Watanabe J, Ichimiya S, Inden Y, Murohara T

    Journal of cardiovascular electrophysiology   32 巻 ( 11 ) 頁: 2933 - 2942   2021年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.15246

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  109. Permanent His-bundle pacing using distal His-bundle electrogram-guided approach in patients with atrioventricular block.

    Suga K, Kato H, Inden Y, Yanagisawa S, Murakami H, Kada K, Tsuboi N, Murohara T

    Pacing and clinical electrophysiology : PACE   44 巻 ( 11 ) 頁: 1907 - 1917   2021年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.14363

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  110. Incidence of Left Atrial Thrombus Development and Imaging Approach in Patients Scheduled for Repeat Catheter Ablation for Atrial Fibrillation. 査読有り

    Yanagisawa S, Inden Y, Riku S, Suga K, Furui K, Nakagomi T, Shimojo M, Okajima T, Shibata R, Murohara T

    The American journal of cardiology   155 巻   頁: 52 - 63   2021年9月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:American Journal of Cardiology  

    The risk for developing left atrial (LA) thrombi after initial catheter ablation for atrial fibrillation (AF) and requirements for imaging evaluation for thrombi screening at repeat ablation is unclear. This study aimed to assess the occurrence of thrombus development and frequency of any imaging study evaluating thrombus formation during repeat ablation for AF. Of 2,066 patients undergoing initial catheter ablation for AF with uninterrupted oral anticoagulation, 615 patients underwent repeat ablation after 258.0 (105.0–882.0) days. We investigated the factors associated with safety outcomes and requirements for thrombus screening. All patients underwent at least one imaging examination to screen for thrombi in the initial session; however, the examination rate decreased to 476 patients (77%) before the repeat session. The frequency of imaging evaluations was 5.0%, 11%, 21%, 84%, and 91% for transesophageal echocardiography and 18%, 33%, 49%, 98%, and 99% for any imaging modality at repeat ablation performed ≤60 days, ≤90 days, ≤180 days, >180 days, and >1 year after the initial session, respectively. Three patients (0.5%) developed LA thrombi at repeat ablation due to identifiable causes, and no patients experienced thromboembolic events when no imaging evaluation was performed. Multivariate analysis revealed that repeat ablation performed after >180 days, non-paroxysmal atrial arrhythmias, and lower left ventricular ejection fraction were predictors of thrombus development and severe spontaneous echocardiography contrast. In conclusion, the risk for thrombus development at repeat ablation for AF was low. There needs to be a risk stratification of the imaging screening for thrombi at repeat ablation.

    DOI: 10.1016/j.amjcard.2021.06.019

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  111. Disappearance pattern and the last remaining earliest pulmonary vein potential during cryoballoon ablation in predicting recurrence and conduction gap site of pulmonary veins.

    Mizutani Y, Inden Y, Yanagisawa S, Kanashiro M, Makino Y, Satake A, Kurobe M, Ichimiya H, Uchida Y, Watanabe J, Ichimiya S, Murohara T

    Heart and vessels   36 巻 ( 8 ) 頁: 1190 - 1200   2021年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    DOI: 10.1007/s00380-021-01785-3

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  112. Dynamic Changes in Electrocardiogram Parameters After Epicardial Substrate Catheter Ablation of Brugada Syndrome. 査読有り Open Access

    Mamiya K, Inden Y, Yanagisawa S, Fujii A, Tomomatsu T, Okamoto H, Riku S, Suga K, Furui K, Nakagomi T, Shibata R, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   85 巻 ( 8 ) 頁: 1283 - 1293   2021年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Circulation Journal  

    Background: Catheter ablation (CA) is effective for recurrent episodes of ventricular fibrillation (VF) in Brugada syndrome (BrS). VF development in BrS is associated with several electrocardiogram (ECG) abnormalities. This study investigated changes in ECG parameters in high-risk BrS patients who underwent epicardial CA. Methods and Results: In all, 27 BrS patients were implanted with an implantable cardioverter-defibrillator (ICD). Patients were divided into 2 groups: (1) an ablation group (n=11) that underwent epicardial CA because of VF recurrence; and (2) a primary prevention (PP) group (n=16) with ICD implantation only. ECG parameters were evaluated before and 12 months after CA and compared with ECG parameters in the PP group. The T wave peak-to-end interval was significantly longer and the number of abnormal spikes in leads V1-V3 at the second, third, and fourth intercostal spaces was greater in the ablation than PP group. After ablation, ST levels and the sum of abnormal spikes in leads V1-V3 were significantly decreased. The mean (±SD) number of ICD shocks decreased markedly during a mean follow-up period of 42.0 months (from 3.8±3.7 to 0.2±0.4/year). Four patients had an ICD shock following the ablation procedure. Greater reductions in ST-segment elevation and abnormal spikes were observed in the group without than with VF recurrence. Conclusions: Improvements in surface ECG parameters appear to be associated with successful ablation in high-risk BrS patients.

    DOI: 10.1253/circj.CJ-20-1060

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  113. The mechanism and prognosis of acute and late improvement in mitral regurgitation after cardiac resynchronization therapy.

    Okamoto H, Inden Y, Yanagisawa S, Fujii A, Tomomatsu T, Mamiya K, Riku S, Suga K, Furui K, Nakagomi T, Shibata R, Murohara T

    Heart and vessels   36 巻 ( 7 ) 頁: 986 - 998   2021年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    DOI: 10.1007/s00380-021-01771-9

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  114. A case of heart failure complicated with double ventricular response triggered by beta blocker.

    Kazama S, Kondo T, Suga K, Yanagisawa S, Morimoto R, Okumura T, Inden Y, Murohara T

    HeartRhythm case reports   7 巻 ( 3 ) 頁: 174 - 177   2021年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:HeartRhythm Case Reports  

    DOI: 10.1016/j.hrcr.2020.12.004

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  115. Early improvement of daily physical activity after catheter ablation for atrial fibrillation in an accelerometer assessment: A prospective pilot study. Open Access

    Yanagisawa S, Inden Y, Fujii A, Sakamoto Y, Tomomatsu T, Mamiya K, Okamoto H, Murohara T, Shibata R

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc   26 巻 ( 1 ) 頁: e12807   2021年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Annals of Noninvasive Electrocardiology  

    DOI: 10.1111/anec.12807

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  116. Safety and efficacy of first-line cryoablation for para-hisian ventricular arrhythmias using a cryomapping protocol approach: A case series. Open Access

    Mizutani Y, Yanagisawa S, Kanashiro M, Inden Y, Murohara T

    Clinical case reports   8 巻 ( 12 ) 頁: 3248 - 3253   2020年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Clinical Case Reports  

    DOI: 10.1002/ccr3.3401

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  117. Autopsy evaluation of the implantation site of a His bundle pacing lead demonstrating selective capture.

    Kato H, Igawa O, Suga K, Murakami H, Kada K, Tsuboi N, Yanagisawa S, Inden Y, Murohara T

    Pacing and clinical electrophysiology : PACE   43 巻 ( 11 ) 頁: 1412 - 1416   2020年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PACE - Pacing and Clinical Electrophysiology  

    DOI: 10.1111/pace.13989

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  118. Periprocedural Management of Cardiac Tamponade During Catheter Ablation for AF Under Uninterrupted DOAC and Warfarin. Open Access

    Yanagisawa S, Inden Y, Ohguchi S, Nagao T, Fujii A, Tomomatsu T, Mamiya K, Okamoto H, Sakamoto Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   6 巻 ( 7 ) 頁: 786 - 795   2020年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2020.02.005

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  119. The impact of the dominant frequency of body surface electrocardiography in patients with persistent atrial fibrillation.

    Murase Y, Inden Y, Shibata R, Yanagisawa S, Fujii A, Ando M, Otake N, Takenaka M, Funabiki J, Sakamoto Y, Murohara T

    Heart and vessels   35 巻 ( 7 ) 頁: 967 - 976   2020年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    DOI: 10.1007/s00380-020-01563-7

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  120. Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P-wave duration and notched P wave. Open Access

    Yanagisawa S, Inden Y, Okamoto H, Fujii A, Sakamoto Y, Mamiya K, Tomomatsu T, Shibata R, Murohara T

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc   25 巻 ( 2 ) 頁: e12712   2020年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/anec.12712

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  121. Anatomical assessment of crosstalk phenomenon during laser balloon ablation with imaging in a patient with unusual atrial hypertrophy.

    Yanagisawa S, Inden Y, Okamoto H, Tomomatsu T, Fujii A, Mamiya K, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   57 巻 ( 1 ) 頁: 157 - 159   2020年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-019-00632-w

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  122. Study design and protocol for evaluating the long-term prognosis of patients receiving his bundle pacing: A multicenter observational study. Open Access

    Yanagisawa S, Inden Y, Kato H, Suzuki H, Fujita M, Ishikawa S, Kanzaki Y, Kamikubo Y, Murase Y, Murohara T, Shibata R

    Journal of arrhythmia   35 巻 ( 5 ) 頁: 760 - 765   2019年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Arrhythmia  

    DOI: 10.1002/joa3.12229

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  123. Correction to: Differences in prothrombotic response between the uninterrupted and interrupted apixaban therapies in patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation: a randomized controlled study.

    Ando M, Inden Y, Yoshida Y, Sairaku A, Yanagisawa S, Suzuki H, Watanabe R, Takenaka M, Maeda M, Murohara T

    Heart and vessels   34 巻 ( 9 ) 頁: 1542   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    DOI: 10.1007/s00380-019-01424-y

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  124. T-wave changes of cardiac memory caused by frequent premature ventricular contractions originating from the right ventricular outflow tract.

    Sakamoto Y, Inden Y, Okamoto H, Mamiya K, Tomomatsu T, Fujii A, Yanagisawa S, Shibata R, Hirai M, Murohara T

    Journal of cardiovascular electrophysiology   30 巻 ( 9 ) 頁: 1549 - 1556   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Cardiovascular Electrophysiology  

    DOI: 10.1111/jce.14008

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  125. Discontinuous contraction in the left ventricle assessed by 2-D speckle tracking echocardiography benefits from CRT.

    Fujii A, Inden Y, Yanagisawa S, Mamiya K, Okamoto H, Sakamoto Y, Tomomatsu T, Shibata R, Murohara T

    Pacing and clinical electrophysiology : PACE   42 巻 ( 9 ) 頁: 1204 - 1212   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PACE - Pacing and Clinical Electrophysiology  

    DOI: 10.1111/pace.13759

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  126. Differences in prothrombotic response between the uninterrupted and interrupted apixaban therapies in patients undergoing cryoballoon ablation for paroxysmal atrial fibrillation: a randomized controlled study.

    Ando M, Inden Y, Yoshida Y, Sairaku A, Yanagisawa S, Suzuki H, Watanabe R, Takenaka M, Maeda M, Murohara T

    Heart and vessels   34 巻 ( 9 ) 頁: 1533 - 1541   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart and Vessels  

    DOI: 10.1007/s00380-019-01370-9

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  127. Identification of precise accessory pathway using ultra-high-resolution three-dimensional mapping system: utility and feasibility in preliminary experience.

    Yanagisawa S, Inden Y, Fujii A, Sakamoto Y, Ichiyanagi H, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   55 巻 ( 2 ) 頁: 241 - 242   2019年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Interventional Cardiac Electrophysiology  

    DOI: 10.1007/s10840-019-00582-3

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  128. His bundle pacing with unusual automaticity.

    Yanagisawa S, Inden Y, Shibata R, Murohara T

    Journal of cardiovascular electrophysiology   30 巻 ( 6 ) 頁: 966 - 968   2019年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.13904

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  129. Adjacent multiple accessory pathways demonstrated on ultra-high-resolution mapping.

    Yanagisawa S, Inden Y, Murohara T

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology   21 巻 ( 5 ) 頁: 723   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/europace/euz044

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  130. Clinical significance of the timing of early recurrence of atrial arrhythmia after pulmonary vein isolation: a two-institution clinical study. 査読有り

    Murase Y, Inden Y, Imai H, Kyo S, Yanagisawa S, Fujii A, Sakamoto Y, Tomomatsu T, Murohara T

    Heart and vessels   34 巻 ( 5 ) 頁: 842 - 850   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-018-1295-1

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  131. Myocardial viability as shown by left ventricular lead pacing threshold and improved dyssynchrony by QRS narrowing predicts the response to cardiac resynchronization therapy. 査読有り

    Takenaka M, Inden Y, Yanagisawa S, Fujii A, Ando M, Funabiki J, Murase Y, Otake N, Sakamoto Y, Shibata R, Murohara T

    Journal of cardiovascular electrophysiology   30 巻 ( 3 ) 頁: 311 - 319   2019年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/jce.13806

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  132. Uninterrupted Direct Oral Anticoagulant and Warfarin Administration in Elderly Patients Undergoing Catheter Ablation for Atrial Fibrillation: A Comparison With Younger Patients. Open Access

    Yanagisawa S, Inden Y, Fujii A, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

    JACC. Clinical electrophysiology   4 巻 ( 5 ) 頁: 592 - 600   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2018.02.013

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  133. Repression of Nitrogen Starvation Responses by Members of the Arabidopsis GARP-Type Transcription Factor NIGT1/HRS1 Subfamily.

    Kiba T, Inaba J, Kudo T, Ueda N, Konishi M, Mitsuda N, Takiguchi Y, Kondou Y, Yoshizumi T, Ohme-Takagi M, Matsui M, Yano K, Yanagisawa S, Sakakibara H

    The Plant cell   30 巻 ( 4 ) 頁: 925 - 945   2018年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1105/tpc.17.00810

    PubMed

  134. Renal function and risk of stroke and bleeding in patients undergoing catheter ablation for atrial fibrillation: Comparison between uninterrupted direct oral anticoagulants and warfarin administration.

    Yanagisawa S, Inden Y, Fujii A, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

    Heart rhythm   15 巻 ( 3 ) 頁: 348 - 354   2018年3月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hrthm.2017.10.033

    Web of Science

    PubMed

  135. Assessment of autonomic nervous system modulation after novel catheter ablation techniques for atrial fibrillation using multiple short-term electrocardiogram recordings.

    Yanagisawa S, Inden Y, Fujii A, Kamikubo Y, Kanzaki Y, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   51 巻 ( 1 ) 頁: 35 - 44   2018年1月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-017-0295-x

    Web of Science

    PubMed

  136. An ECG Index of P-Wave Force Predicts the Recurrence of Atrial Fibrillation after Pulmonary Vein Isolation.

    Kanzaki Y, Inden Y, Ando M, Kamikubo Y, Ito T, Mizutani Y, Kato H, Fujii A, Yanagisawa S, Hirai M, Murohara T

    Pacing and clinical electrophysiology : PACE   39 巻 ( 11 ) 頁: 1191 - 1197   2016年11月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PACE - Pacing and Clinical Electrophysiology  

    DOI: 10.1111/pace.12956

    Scopus

    PubMed

  137. Effect and Significance of Early Reablation for the Treatment of Early Recurrence of Atrial Fibrillation After Catheter Ablation.

    Yanagisawa S, Inden Y, Kato H, Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Ando M, Hirai M, Shibata R, Murohara T

    The American journal of cardiology   118 巻 ( 6 ) 頁: 833 - 841   2016年9月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.amjcard.2016.06.045

    PubMed

  138. Body mass index is associated with prognosis in Japanese elderly patients with atrial fibrillation: an observational study from the outpatient clinic.

    Yanagisawa S, Inden Y, Yoshida N, Kato H, Miyoshi-Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Hirai M, Murohara T

    Heart and vessels   31 巻 ( 9 ) 頁: 1553 - 61   2016年9月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00380-015-0765-y

    PubMed

  139. Decrease in B-Type Natriuretic Peptide Levels and Successful Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure.

    Yanagisawa S, Inden Y, Kato H, Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Hirai M, Murohara T

    Pacing and clinical electrophysiology : PACE   39 巻 ( 3 ) 頁: 225 - 34   2016年3月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.12788

    PubMed

  140. Elevated Red Blood Cell Distribution Width Predicts Recurrence After Catheter Ablation for Atrial Fibrillation in Patients With Heart Failure - Comparison With Non-Heart Failure Patients. Open Access

    Yanagisawa S, Inden Y, Kato H, Miyoshi A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Hirai M, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   80 巻 ( 3 ) 頁: 627 - 38   2016年

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.CJ-15-1152

    Open Access

    PubMed

  141. Differences in activated clotting time among uninterrupted anticoagulants during the periprocedural period of atrial fibrillation ablation.

    Nagao T, Inden Y, Yanagisawa S, Kato H, Ishikawa S, Okumura S, Mizutani Y, Ito T, Yamamoto T, Yoshida N, Hirai M, Murohara T

    Heart rhythm   12 巻 ( 9 ) 頁: 1972 - 8   2015年9月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart Rhythm  

    DOI: 10.1016/j.hrthm.2015.04.016

    Scopus

    PubMed

  142. Impact of cardiac resynchronization therapy-defibrillator implantation on the association between body mass index and prognosis in patients with heart failure.

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Ishikawa S, Kato H, Okumura S, Miyoshi-Fujii A, Nagao T, Yamamoto T, Mizutani Y, Ito T, Hirai M, Murohara T

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   43 巻 ( 3 ) 頁: 269 - 77   2015年9月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-015-0015-3

    PubMed

  143. Alogliptin, a dipeptidyl peptidase-4 inhibitor, regulates the atrial arrhythmogenic substrate in rabbits.

    Yamamoto T, Shimano M, Inden Y, Takefuji M, Yanagisawa S, Yoshida N, Tsuji Y, Hirai M, Murohara T

    Heart rhythm   12 巻 ( 6 ) 頁: 1362 - 9   2015年6月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Heart Rhythm  

    DOI: 10.1016/j.hrthm.2015.03.010

    Scopus

    PubMed

  144. Efficacy and safety of apixaban in the patients undergoing the ablation of atrial fibrillation.

    Nagao T, Inden Y, Shimano M, Fujita M, Yanagisawa S, Kato H, Ishikawa S, Miyoshi A, Okumura S, Ohguchi S, Yamamoto T, Yoshida N, Hirai M, Murohara T

    Pacing and clinical electrophysiology : PACE   38 巻 ( 2 ) 頁: 155 - 63   2015年2月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PACE - Pacing and Clinical Electrophysiology  

    DOI: 10.1111/pace.12553

    Scopus

    PubMed

  145. Feasibility and safety of uninterrupted dabigatran therapy in patients undergoing ablation for atrial fibrillation. Open Access

    Nagao T, Inden Y, Shimano M, Fujita M, Yanagisawa S, Kato H, Ishikawa S, Miyoshi A, Okumura S, Ohguchi S, Yamamoto T, Yoshida N, Hirai M, Murohara T

    Internal medicine (Tokyo, Japan)   54 巻 ( 10 ) 頁: 1167 - 73   2015年

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Internal Medicine  

    DOI: 10.2169/internalmedicine.54.3520

    Open Access

    Scopus

    PubMed

  146. Clinical characteristics and predictors of super-response to cardiac resynchronization therapy: a combination of predictive factors.

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T

    Pacing and clinical electrophysiology : PACE   37 巻 ( 11 ) 頁: 1553 - 64   2014年11月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.12506

    PubMed

  147. Clinical outcome of implantable cardioverter defibrillators with recalled and non-recalled leads in Japanese patients. Increased failure rate of the Sprint Fidelis lead.

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Ichiyanagi H, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T

    Circulation journal : official journal of the Japanese Circulation Society   78 巻 ( 2 ) 頁: 353 - 9   2014年

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.cj-13-1040

    PubMed

  148. Comparison of medically versus surgically treated acute type a aortic dissection in patients &lt;80 years old versus patients ≥80 years old. 査読有り

    Yanagisawa S, Yuasa T, Suzuki N, Hirai T, Yasuda N, Miki K, Yasuura K, Horiuchi K, Tanaka T

    The American journal of cardiology   108 巻 ( 3 ) 頁: 453 - 9   2011年8月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.amjcard.2011.03.067

    PubMed

  149. Programmed synthesis of tetraarylthiophenes through sequential C-H arylation.

    Yanagisawa S, Ueda K, Sekizawa H, Itami K

    Journal of the American Chemical Society   131 巻 ( 41 ) 頁: 14622 - 3   2009年10月

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1021/ja906215b

    PubMed

  150. Prothrombotic Responses After Catheter Ablation for Atrial Fibrillation During Uninterrupted Oral Anticoagulant Agent Administration. 査読有り

      5 巻 ( 12 ) 頁: 1418-1427   2019年12月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jacep.2019.09.002

    Scopus

    PubMed

  151. Vagal response in cryoballoon ablation of atrial fibrillation and autonomic nervous system: Utility of epicardial adipose tissue location 査読有り

    Yanagisawa Satoshi, Inden Yasuya, Mizutani Yoshiaki, Fujii Aya, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Hattori Tetsuyoshi, Shibata Rei, Murohara Toyoaki

    JOURNAL OF ARRHYTHMIA   33 巻 ( 4 ) 頁: 275-282   2017年8月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.joa.2017.03.001

    Web of Science

    PubMed

  152. Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A potential effect of non-pulmonary vein foci. 査読有り

    Yanagisawa S, Inden Y, Kato H, Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Ando M, Hirai M, Shibata R, Murohara T.

    J Cardiol.   69 巻 ( 1 ) 頁: 3-10   2017年1月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.jjcc.2016.07.008

  153. Effect and Significance of Early Reablation for the Treatment of Early Recurrence of Atrial Fibrillation After Catheter Ablation. 査読有り

    Yanagisawa S, Inden Y, Kato H, Fujii A, Mizutani Y, Ito T, Kamikubo Y, Kanzaki Y, Ando M, Hirai M, Shibata R, Murohara T.

    Am J Cardiol.   118 巻 ( 6 ) 頁: 833-841   2016年9月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.amjcard.2016.06.045

  154. Impact of cardiac resynchronization therapy-defibrillator implantation on the association between body mass index and prognosis in patients with heart failure. 査読有り

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Ishikawa S, Kato H, Okumura S, Miyoshi-Fujii A, Nagao T, Yamamoto T, Mizutani Y, Ito T, Hirai M, Murohara T.

    J Interv Card Electrophysiol.   43 巻 ( 3 ) 頁: 269-277   2015年9月

     詳細を見る

    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10840-015-0015-3

  155. Clinical characteristics and predictors of super-response to cardiac resynchronization therapy: a combination of predictive factors. 査読有り

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T.

    Pacing Clin Electrophysiol.   37 巻 ( 11 ) 頁: 1553-1564   2014年11月

     詳細を見る

    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/pace.12506

  156. Clinical outcome of implantable cardioverter defibrillators with recalled and non-recalled leads in Japanese patients. Increased failure rate of the Sprint Fidelis lead. 査読有り

    Yanagisawa S, Inden Y, Shimano M, Yoshida N, Ichiyanagi H, Fujita M, Ohguchi S, Ishikawa S, Kato H, Okumura S, Miyoshi A, Nagao T, Yamamoto T, Hirai M, Murohara T.

    Circ J.   78 巻 ( 2 ) 頁: 353-359   2014年2月

     詳細を見る

    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  157. Comparison of medically versus surgically treated acute type a aortic dissection in patients <80 years old versus patients >=80 years old. 査読有り

    Yanagisawa S, Yuasa T, Suzuki N, Hirai T, Yasuda N, Miki K, Yasuura K, Horiuchi K, Tanaka T.

    Am J Cardiol.   108 巻 ( 3 ) 頁: 453-459   2011年8月

     詳細を見る

    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  158. The prognostic value of treadmill exercise testing in very elderly patients: Heart rate recovery as a predictor of mortality in octogenarians. 査読有り

    Yanagisawa S, Miki K, Yasuda N, Hirai T, Suzuki N, Tanaka T.

    Europace.   13 巻 ( 1 ) 頁: 114-120   2011年1月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/europace/euq422

  159. Clinical outcomes and prognostic factor for acute heart failure in nonagenarians: Impact of hypoalbuminemia on mortality. 査読有り

    Yanagisawa S, Miki K, Yasuda N, Hirai T, Suzuki N, Tanaka T.

    Int J Cardiol.   145 巻 ( 3 ) 頁: 574-576   2010年12月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijcard.2010.05.061

  160. Poor tolerance of beta-blockers by elderly patients with heart failure. 査読有り

    Yanagisawa S, Suzuki N, Tanaka T.

    Clin Interv Aging.   5 巻   頁: 365-368   2010年11月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2147/CIA.S15158

  161. Right ventricular outflow tract obstruction: metastatic thyroid carcinoma. 査読有り

    Yanagisawa S, Suzuki Y, Yuasa T, Tanaka T.

    J Am Coll Cardiol.   55 巻 ( 11 ) 頁: 1159   2010年3月

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  162. Clinical diagnosis of Schistosoma japonicum infection complicating infective endocarditis and liver cirrhosis. 査読有り

    Yanagisawa S, Yuasa T, Tanaka T.

    Intern Med.   44 巻 ( 11 ) 頁: 1001-1005   2010年

     詳細を見る

    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2169/internalmedicine.49.3121

▼全件表示

書籍等出版物 2

  1. 人体のメカニズムから学ぶ臨床工学 循環器治療学 頻脈性不整脈の発生機序

    柳澤 哲、室原豊明( 担当: 共著)

    メジカルビュー社  2017年 

     詳細を見る

    総ページ数:7   記述言語:日本語 著書種別:教科書・概説・概論

  2. BIO Clinica, TOPICS 心房細動カテーテルアブレーション治療の周術期抗凝固療法

    柳澤 哲( 担当: 共著)

    北隆館  2018年11月 

     詳細を見る

    記述言語:日本語 著書種別:学術書

MISC 1

  1. Septal coronary artery fistula after left bundle branch area pacing assessed by multi-imaging modalities and shunt volume quantification

    Kato H, Yanagisawa S, Ota R, Murakami H, Kada K, Tsuboi N, Inden Y, Murohara T  

    Pacing and clinical electrophysiology : PACE45 巻 ( 11 ) 頁: 1299 - 1302   2022年11月

     詳細を見る

    記述言語:英語   出版者・発行元:PACE - Pacing and Clinical Electrophysiology  

    Septal coronary artery fistula is a rare but concerning complication of left bundle branch area pacing (LBBAP). We report the case of an 82-year-old man who was indicated for cardiac resynchronization therapy and underwent LBBAP. The patient had no chest symptoms during or after implantation. Postoperative echocardiography demonstrated a new abnormal tunnel inside the interventricular septum (IVS) and shunt flow from the IVS toward the right ventricle. Coronary angiography confirmed a septal coronary artery fistula, which might have been formed by failed deep screw attempts. Since the shunt volume assessed by the Qp/Qs was small, the patient was treated conservatively.

    DOI: 10.1111/pace.14548

    Web of Science

    Scopus

    PubMed

共同研究・競争的資金等の研究課題 2

  1. 微小栓子シグナル信号解析法を用いた心筋焼灼時の血栓リスク評価と血液凝固マーカーとの関連探索

    2023年 - 2024年

    鈴木謙三記念医科学応用研究財団 研究助成金 

      詳細を見る

    担当区分:研究代表者 

  2. 加速度センサー搭載型活動量計を用いた日常生活の身体活動強度評価と心房細動アブレーション治療後の予後改善への試み

    2016年 - 2017年

    鈴木謙三記念医科学応用研究財団 研究助成金 

    柳澤 哲

      詳細を見る

    資金種別:競争的資金

科研費 4

  1. 頸動脈波の微小栓子シグナル信号解析を用いた、有効で安全な次世代不整脈治療法の確立

    研究課題/研究課題番号:23K07549  2023年4月 - 2027年3月

    科学研究費補助金   基盤研究(C)

      詳細を見る

    担当区分:研究代表者 

  2. 新しいヒス束ペースメーカの長期予後と刺激伝導系の解明を目指した多施設共同研究

    研究課題/研究課題番号:19K17558  2019年4月 - 2023年3月

    科学研究費助成事業  若手研究

    柳澤 哲

      詳細を見る

    担当区分:研究代表者 

    配分額:4160000円 ( 直接経費:3200000円 、 間接経費:960000円 )

    本研究は、新しいペーシングシステムであるヒス束ペーシングの有効性と安全性、さらにその長期的な予後について多施設で検討を行うものである。日本では、ヒス束ペースメーカは臨床診療に導入されてから間もないため、各施設ともまだ症例数が少なく、その適応や効果について模索している段階である。本研究の目的は、ヒス束ペースメーカを対象として前向きに多施設の症例登録・共同研究を行い、多くのヒス束ペースメーカの症例を収集して長期の追跡を行うことで、その有効性と安全性だけでなく、心機能への影響や長期的な予後について検証を行うものである。
    ヒス束ペースメーカは2017年本邦に導入された全く新しいペーシングシステムである。刺激伝導系であるヒス束を直接捕捉・ペーシングすることにより、従来の右心室ペーシングで懸念された非効率的な心室同期不全や、心拍出量低下から引き起こされる心不全発症を回避できる可能性がある。日本では臨床診療に導入されてから間もないため、各施設ともまだ症例数が少なくその適応や効果について模索している段階である。本研究の目的は、ヒス束ペースメーカ症例を対象として前向きで多施設の共同研究を行い、ヒス束ペースメーカの有効性と安全性、心機能への影響や長期的な予後について検証を行うものである。
    今年度は研究プロトコル・計画について、主管実施施設である当病院の生命倫理審査委員会からの承認が下りた。引き続き共同研究機関において、それぞれの倫理審査委員会から研究実施の承認が得られた。最初にWEBシステムでの症例登録システムを構築し、多施設での症例登録や入力がすみやかに行えるように準備と管理を行った。その後症例の登録と研究を開始しており、これまでに約1年間で25例のヒス束ペースメーカシステム植え込み症例の登録が得られた。現在登録完了施設は6施設からなり、年齢も50から80歳台と多岐にわたっている。同時に、個々の症例について6か月後の短期評価項目の調査入力を行っている状況である。また、本研究のデザイン/プロトコル論文を作成して投稿し、日本不整脈心電学会関連の雑誌に掲載となった。
    症例の組み入れ登録を開始しているが、現時点ではやや症例の見積もり数と比較して不足がちな状況である。
    今後も引き続き症例登録を続けて、できるだけ多くの症例登録を目指す。また得られた結果をもとに分析を開始していく予定である。

  3. 心房細動アブレーション治療の予後改善をめざした積極的生活習慣改善プログラムの導入

    研究課題/研究課題番号:16K19399  2016年4月 - 2019年3月

    科学研究費助成事業  若手研究(B)

    柳澤 哲

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    担当区分:研究代表者 

    配分額:3900000円 ( 直接経費:3000000円 、 間接経費:900000円 )

    加速度センサー搭載型の活動量計を用いて、心房細動カテーテルアブレーション治療前後の運動機能の評価を行った。約半年間の観察期間では、術前に比べて平均1日歩数、最大歩数において増加傾向が認められ、運動強度も増加する傾向が認められた。活動量や運動機能の改善は、アブレーション術後の比較的早期から認められており、心房細動の抑制や血行動態の改善による速やかな運動能力と活動への効果が現れることが確認された。
    本研究は、心房細動アブレーション治療前後の運動機能や活動能力を、活動量計を用いて客観的に評価したものである。その成果として、活動量や運動能力の改善が、アブレーション術後比較的早期から改善していることが判明した。心房細動カテーテルアブレーション治療後では血管穿刺や自律神経への影響もあるが、運動機能と活動量への影響が早期に認められたことは、術後のADL向上や早期社会復帰への指標となりえることが考えられる。

  4. 心電図周波数解析と心内ローターマッピングを用いた新しい心房細動評価と治療法の開発

    研究課題/研究課題番号:15K09076  2015年4月 - 2018年3月

    科学研究費助成事業  基盤研究(C)

    因田 恭也, 室原 豊明, 吉田 直樹, 柳澤 哲, 山崎 正俊

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    担当区分:研究分担者 

    体表面心電図の心房細動波からDominant Frequency (DF)が得られることが知られている。われわれはアブレーションを行った持続性心房細動患者の予後とDFとの関連を調べた。DFが高いとアブレーション後の再発が多く、DFは心房筋のリモデリングを反映していると考えられた。
    また心房細動中のrotorを観察すると、左心房前壁および後壁にrotorが多く観察され、これらをablationにて焼灼すると、心房細動が停止する症例が認められた。またその後の洞調律維持も良好であった。心房細動rotorの評価は、アブレーション治療時の焼灼部位決定に有用であった。