Updated on 2025/04/21

写真a

 
SATO Takehito
 
Organization
Nagoya University Hospital Anesthesiology Lecturer of hospital
Title
Lecturer of hospital

Degree 1

  1. 博士(医学) ( 2021.2 ) 

Research Interests 8

  1. 小児麻酔

  2. 神経麻酔

  3. 麻酔科学

  4. Awake craniotomy

  5. 集中治療

  6. Macrophage

  7. ペインクリニック

  8. 脳境界マクロファージ

Research Areas 1

  1. Life Science / Anesthesiology

Research History 2

  1. Nagoya University   Nagoya University Hospital Anesthesiology   Lecturer of hospital

    2025.4

  2. Nagoya University   Assistant Professor of Hospital

    2020.4 - 2025.3

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    2016.4 - 2020.3

      More details

    Country: Japan

  2. Akita University   Faculty of Medicine

    - 2009.3

      More details

    Country: Japan

Professional Memberships 10

  1. 日本麻酔科学会

  2. ペインクリニック学会

  3. 臨床麻酔学会

  4. 日本集中治療医学会

  5. 心臓血管麻酔学会

▼display all

Committee Memberships 8

  1.   麻酔科学会 神経ワーキンググループ  

    2018.4 - 2019.6   

      More details

    Committee type:Academic society

  2. 日本集中治療医学会   NEXT WAVE From U45 メンバー  

    2025.1   

  3.   日本集中治療医学会・日本呼吸器学会・日本呼吸療法医学会 日本版ARDS診療ガイドライン2026 ワーキンググループメンバー  

    2024.8   

  4. 日本Awake Surgery学会   運営委員  

    2024.8   

  5. 日本麻酔科学会   U-40委員  

    2023.6   

      More details

    Committee type:Academic society

▼display all

Awards 4

  1. 神経 優秀演題

    2024.6   第71回日本麻酔科学会総会  

  2. English Award

    2024.4   Japan Society of Regional Anesthesia  

  3. 第13回日本麻酔科学会北海道・東北支部会 優秀演題

    2023.9  

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

  4. 神経セッション 優秀演題賞

    2018.5   日本麻酔科学会  

     More details

    Award type:International academic award (Japan or overseas)  Country:Japan

 

Papers 35

  1. Prospective Randomized Controlled Trial Comparing Anesthetic Management With Remimazolam Besylate and Flumazenil Versus Propofol During Awake Craniotomy Following an Asleep-awake-asleep Method Reviewed International journal

    Takehito Sato, Takahiro Ando, Kanako Ozeki, Ichiko Asano, Yachiyo Kuwatsuka, Masahiko Ando, Kazuya Motomura, Kimitoshi Nishiwaki

    Journal of Neurosurgical Anesthesiology   Vol. 37 ( 1 ) page: 40 - 46   2025.1

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Ovid Technologies (Wolters Kluwer Health)  

    Background:

    Awake craniotomy is performed to resect brain tumors in eloquent brain areas to maximize tumor reduction and minimize neurological damage. Evidence suggests that intraoperative anesthetic management of awake craniotomy with remimazolam is safe. We compared the time to arousal and efficacy of anesthetic management with remimazolam and propofol during awake craniotomy.

    Methods:

    In a single-institution randomized, prospective study, patients who underwent elective awake craniotomy were randomized to receive remimazolam and reversal with flumazenil (group R) or propofol (group P). The primary end point was time to awaken. Secondary end points were time to loss of consciousness during induction of anesthesia, the frequency of intraoperative complications (pain, hypertension, seizures, nausea, vomiting, and delayed arousal), and postoperative nausea and vomiting. Intraoperative task performance was assessed using a numerical rating scale (NRS) score.

    Results:

    Fifty-eight patients were recruited, of which 52 (26 in each group) were available for the efficacy analysis. Patients in group R had faster mean (±SD) arousal times than those in the P group (890.8±239.8 vs. 1075.4±317.5 s; P=0.013)and higher and more reliable intraoperative task performance (NRS score 8.81±1.50 vs. 7.69±2.36; P=0.043). There were no significant intraoperative complications.

    Conclusions:

    Compared with propofol, remimazolam was associated with more rapid loss of consciousness and, after administration of flumazenil, with faster arousal times and improved intraoperative task performance.

    DOI: 10.1097/ana.0000000000000975

    PubMed

  2. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024. International journal

    Nobuaki Shime, Taka-Aki Nakada, Tomoaki Yatabe, Kazuma Yamakawa, Yoshitaka Aoki, Shigeaki Inoue, Toshiaki Iba, Hiroshi Ogura, Yusuke Kawai, Atsushi Kawaguchi, Tatsuya Kawasaki, Yutaka Kondo, Masaaki Sakuraya, Shunsuke Taito, Kent Doi, Hideki Hashimoto, Yoshitaka Hara, Tatsuma Fukuda, Asako Matsushima, Moritoki Egi, Shigeki Kushimoto, Takehiko Oami, Kazuya Kikutani, Yuki Kotani, Gen Aikawa, Makoto Aoki, Masayuki Akatsuka, Hideki Asai, Toshikazu Abe, Yu Amemiya, Ryo Ishizawa, Tadashi Ishihara, Tadayoshi Ishimaru, Yusuke Itosu, Hiroyasu Inoue, Hisashi Imahase, Haruki Imura, Naoya Iwasaki, Noritaka Ushio, Masatoshi Uchida, Michiko Uchi, Takeshi Umegaki, Yutaka Umemura, Akira Endo, Marina Oi, Akira Ouchi, Itsuki Osawa, Yoshiyasu Oshima, Kohei Ota, Takanori Ohno, Yohei Okada, Hiromu Okano, Yoshihito Ogawa, Masahiro Kashiura, Daisuke Kasugai, Ken-Ichi Kano, Ryo Kamidani, Akira Kawauchi, Sadatoshi Kawakami, Daisuke Kawakami, Yusuke Kawamura, Kenji Kandori, Yuki Kishihara, Sho Kimura, Kenji Kubo, Tomoki Kuribara, Hiroyuki Koami, Shigeru Koba, Takehito Sato, Ren Sato, Yusuke Sawada, Haruka Shida, Tadanaga Shimada, Motohiro Shimizu, Kazushige Shimizu, Takuto Shiraishi, Toru Shinkai, Akihito Tampo, Gaku Sugiura, Kensuke Sugimoto, Hiroshi Sugimoto, Tomohiro Suhara, Motohiro Sekino, Kenji Sonota, Mahoko Taito, Nozomi Takahashi, Jun Takeshita, Chikashi Takeda, Junko Tatsuno, Aiko Tanaka, Masanori Tani, Atsushi Tanikawa, Hao Chen, Takumi Tsuchida, Yusuke Tsutsumi, Takefumi Tsunemitsu, Ryo Deguchi, Kenichi Tetsuhara, Takero Terayama, Yuki Togami, Takaaki Totoki, Yoshinori Tomoda, Shunichiro Nakao, Hiroki Nagasawa, Yasuhisa Nakatani, Nobuto Nakanishi, Norihiro Nishioka, Mitsuaki Nishikimi, Satoko Noguchi, Suguru Nonami, Osamu Nomura, Katsuhiko Hashimoto, Junji Hatakeyama, Yasutaka Hamai, Mayu Hikone, Ryo Hisamune, Tomoya Hirose, Ryota Fuke, Ryo Fujii, Naoki Fujie, Jun Fujinaga, Yoshihisa Fujinami, Sho Fujiwara, Hiraku Funakoshi, Koichiro Homma, Yuto Makino, Hiroshi Matsuura, Ayaka Matsuoka, Tadashi Matsuoka, Yosuke Matsumura, Akito Mizuno, Sohma Miyamoto, Yukari Miyoshi, Satoshi Murata, Teppei Murata, Hiromasa Yakushiji, Shunsuke Yasuo, Kohei Yamada, Hiroyuki Yamada, Ryo Yamamoto, Ryohei Yamamoto, Tetsuya Yumoto, Yuji Yoshida, Shodai Yoshihiro, Satoshi Yoshimura, Jumpei Yoshimura, Hiroshi Yonekura, Yuki Wakabayashi, Takeshi Wada, Shinichi Watanabe, Atsuhiro Ijiri, Kei Ugata, Shuji Uda, Ryuta Onodera, Masaki Takahashi, Satoshi Nakajima, Junta Honda, Tsuguhiro Matsumoto

    Journal of intensive care   Vol. 13 ( 1 ) page: 15 - 15   2025.3

     More details

    Language:English  

    The 2024 revised edition of the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock (J-SSCG 2024) is published by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine. This is the fourth revision since the first edition was published in 2012. The purpose of the guidelines is to assist healthcare providers in making appropriate decisions in the treatment of sepsis and septic shock, leading to improved patient outcomes. We aimed to create guidelines that are easy to understand and use for physicians who recognize sepsis and provide initial management, specialized physicians who take over the treatment, and multidisciplinary healthcare providers, including nurses, physical therapists, clinical engineers, and pharmacists. The J-SSCG 2024 covers the following nine areas: diagnosis of sepsis and source control, antimicrobial therapy, initial resuscitation, blood purification, disseminated intravascular coagulation, adjunctive therapy, post-intensive care syndrome, patient and family care, and pediatrics. In these areas, we extracted 78 important clinical issues. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 42 GRADE-based recommendations, 7 good practice statements, and 22 information-to-background questions were created as responses to clinical questions. We also described 12 future research questions.

    DOI: 10.1186/s40560-025-00776-0

    PubMed

  3. A Case of a One-Month-Old Infant Who Underwent Oral Intubation With Tongue Traction After Decompressing an Oral Cyst Reviewed

    Takehito Sato, Yui Somura, Masashi Takakura, Takahiro Tamura, Shogo Suzuki

    Cureus     2025.2

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7759/cureus.79132

  4. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024. Reviewed International journal

    Nobuaki Shime, Taka-Aki Nakada, Tomoaki Yatabe, Kazuma Yamakawa, Yoshitaka Aoki, Shigeaki Inoue, Toshiaki Iba, Hiroshi Ogura, Yusuke Kawai, Atsushi Kawaguchi, Tatsuya Kawasaki, Yutaka Kondo, Masaaki Sakuraya, Shunsuke Taito, Kent Doi, Hideki Hashimoto, Yoshitaka Hara, Tatsuma Fukuda, Asako Matsushima, Moritoki Egi, Shigeki Kushimoto, Takehiko Oami, Kazuya Kikutani, Yuki Kotani, Gen Aikawa, Makoto Aoki, Masayuki Akatsuka, Hideki Asai, Toshikazu Abe, Yu Amemiya, Ryo Ishizawa, Tadashi Ishihara, Tadayoshi Ishimaru, Yusuke Itosu, Hiroyasu Inoue, Hisashi Imahase, Haruki Imura, Naoya Iwasaki, Noritaka Ushio, Masatoshi Uchida, Michiko Uchi, Takeshi Umegaki, Yutaka Umemura, Akira Endo, Marina Oi, Akira Ouchi, Itsuki Osawa, Yoshiyasu Oshima, Kohei Ota, Takanori Ohno, Yohei Okada, Hiromu Okano, Yoshihito Ogawa, Masahiro Kashiura, Daisuke Kasugai, Ken-Ichi Kano, Ryo Kamidani, Akira Kawauchi, Sadatoshi Kawakami, Daisuke Kawakami, Yusuke Kawamura, Kenji Kandori, Yuki Kishihara, Sho Kimura, Kenji Kubo, Tomoki Kuribara, Hiroyuki Koami, Shigeru Koba, Takehito Sato, Ren Sato, Yusuke Sawada, Haruka Shida, Tadanaga Shimada, Motohiro Shimizu, Kazushige Shimizu, Takuto Shiraishi, Toru Shinkai, Akihito Tampo, Gaku Sugiura, Kensuke Sugimoto, Hiroshi Sugimoto, Tomohiro Suhara, Motohiro Sekino, Kenji Sonota, Mahoko Taito, Nozomi Takahashi, Jun Takeshita, Chikashi Takeda, Junko Tatsuno, Aiko Tanaka, Masanori Tani, Atsushi Tanikawa, Hao Chen, Takumi Tsuchida, Yusuke Tsutsumi, Takefumi Tsunemitsu, Ryo Deguchi, Kenichi Tetsuhara, Takero Terayama, Yuki Togami, Takaaki Totoki, Yoshinori Tomoda, Shunichiro Nakao, Hiroki Nagasawa, Yasuhisa Nakatani, Nobuto Nakanishi, Norihiro Nishioka, Mitsuaki Nishikimi, Satoko Noguchi, Suguru Nonami, Osamu Nomura, Katsuhiko Hashimoto, Junji Hatakeyama, Yasutaka Hamai, Mayu Hikone, Ryo Hisamune, Tomoya Hirose, Ryota Fuke, Ryo Fujii, Naoki Fujie, Jun Fujinaga, Yoshihisa Fujinami, Sho Fujiwara, Hiraku Funakoshi, Koichiro Homma, Yuto Makino, Hiroshi Matsuura, Ayaka Matsuoka, Tadashi Matsuoka, Yosuke Matsumura, Akito Mizuno, Sohma Miyamoto, Yukari Miyoshi, Satoshi Murata, Teppei Murata, Hiromasa Yakushiji, Shunsuke Yasuo, Kohei Yamada, Hiroyuki Yamada, Ryo Yamamoto, Ryohei Yamamoto, Tetsuya Yumoto, Yuji Yoshida, Shodai Yoshihiro, Satoshi Yoshimura, Jumpei Yoshimura, Hiroshi Yonekura, Yuki Wakabayashi, Takeshi Wada, Shinichi Watanabe, Atsuhiro Ijiri, Kei Ugata, Shuji Uda, Ryuta Onodera, Masaki Takahashi, Satoshi Nakajima, Junta Honda, Tsuguhiro Matsumoto

    Acute medicine & surgery   Vol. 12 ( 1 ) page: e70037   2025

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    The 2024 revised edition of the Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock (J-SSCG 2024) is published by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine. This is the fourth revision since the first edition was published in 2012. The purpose of the guidelines is to assist healthcare providers in making appropriate decisions in the treatment of sepsis and septic shock, leading to improved patient outcomes. We aimed to create guidelines that are easy to understand and use for physicians who recognize sepsis and provide initial management, specialized physicians who take over the treatment, and multidisciplinary healthcare providers, including nurses, physical therapists, clinical engineers, and pharmacists. The J-SSCG 2024 covers the following nine areas: diagnosis of sepsis and source control, antimicrobial therapy, initial resuscitation, blood purification, disseminated intravascular coagulation, adjunctive therapy, post-intensive care syndrome, patient and family care, and pediatrics. In these areas, we extracted 78 important clinical issues. The GRADE (Grading of Recommendations Assessment, Development and Evaluation) method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members. As a result, 42 GRADE-based recommendations, 7 good practice statements, and 22 information-to-background questions were created as responses to clinical questions. We also described 12 future research questions.

    DOI: 10.1002/ams2.70037

    PubMed

  5. Successful analgesic treatment with continuous sacral epidural ethanol injection therapy for anal pain caused by multiple metastases of malignant pheochromocytoma Reviewed

    Takehito Sato, Shigeru Inoue, Ichiko Asano, Takahiro Ando, Yasuyuki Shibata

    JA Clinical Reports     2024.12

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40981-024-00760-x

▼display all

Books 1

  1. 最先端外科手術の麻酔管理

    稲垣 喜三 他( Role: Contributor ,  胸部大動脈瘤ステント留置術)

    克誠堂出版  2016.6 

     More details

    Language:Japanese Book type:Textbook, survey, introduction

MISC 39

  1. A case of successful continuous sacral epidural administration of ethanol therapy for anal pain due to multiple metastasis of malignant pheochromocytoma

    Takehito Sato, Ichiko Asano, Takahiro Ando

    Koreanesthesia2024     2024.11

     More details

    Language:English  

  2. 肥満患者における 覚醒下脳腫瘍摘出術の麻酔管理にレミマゾラムを使用した症例

    佐藤 威仁, 田村, 高廣, 西脇 公俊

    第22回日本Awake Surgery学会 抄録     2024.7

  3. 強大音曝露後の耳痛,聞こえ方の違和感に対し内服薬と星状神経節ブロックが奏効した1例報告

    浅野 市子, 佐藤 威仁, 西脇 公俊

    日本ペインクリニック学会誌   Vol. 31 ( 6 ) page: 126 - 127   2024.6

     More details

    Language:Japanese   Publisher:(一社)日本ペインクリニック学会  

  4. Investigation of agitation during awake craniotomy and the relationship between the effect of discomfort associated with urinary catheter insertion and the preventive effect of lidocaine

    Takehito Sato

    Euroanaesthesia 2024     2024.5

     More details

    Publishing type:Article, review, commentary, editorial, etc. (international conference proceedings)  

  5. A successful case of pain management including nerve blocks and implantation of spinal cord stimulation (SCS) for severe lower limb ischemia due to localized scleroderma.

    Takehito Sato, Ichiko Asano, Takahiro Ando

        2024.4

     More details

    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (international conference proceedings)  

▼display all

Presentations 41

  1. Awake craniotomyの麻酔を上手に行うために 合併症の対応 Invited

    佐藤 威仁

    第41回臨床麻酔学会  2021.11.6 

     More details

    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:札幌  

  2. レミマゾラムを極める 覚醒下開頭術の上手な使い方 Invited

    佐藤 威仁

    第25回神経麻酔集中治療学会  2021.6.19 

     More details

    Event date: 2021.6

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:Web開催   Country:Japan  

  3. The case of a 1-month-old infant with emergency airway due to a giant lymphangioma of floor the mouth International conference

    Takehito Sato, Masashi Takakura, Yui Somura, Takahiro Tamura, Shogo Suzuki

    5th Joint Scientific Congress of TSCCM (Thai) and JSICM  2025.3.16 

     More details

    Event date: 2025.3

    Language:English   Presentation type:Poster presentation  

    Venue:Hakata,Fukuoka,Japan   Country:Japan  

  4. A case of successful continuous sacral epidural administration of ethanol therapy for anal pain due to multiple metastasis of malignant pheochromocytoma International conference

    Takehito Sato,Ichiko Asano,Takahiro Ando

    Koreanesthesa2024  2024.11.15 

     More details

    Event date: 2024.11

    Language:English   Presentation type:Poster presentation  

    Country:Korea, Republic of  

  5. Anesthetic manaement of awake craniotomy in elderly patient with remimazolam. International conference

    Takehito Sato,Takahiro Ando,Kimitoshi Nishiwaki

    Koreanesthesia 2023  2023.11.10 

     More details

    Event date: 2023.11

    Language:English   Presentation type:Poster presentation  

    Venue:Seoul, South Korea   Country:Korea, Republic of  

▼display all

Research Project for Joint Research, Competitive Funding, etc. 1

  1. Asleep-Awake-Asleep法で行われる覚醒下脳腫瘍摘出術における レミマゾラム投与の有用性についての検討

    2020.12

    先端医療開発経費③ 

    佐藤 威仁、西脇 公俊

      More details

    Authorship:Coinvestigator(s) 

    Grant amount:\1800000

KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. 中枢神経境界関連マクロファージを標的とした線維筋痛症発症メカニズムの探索

    Grant number:25K19836  2025.4 - 2028.3

    科学研究費助成事業  若手研究

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

  2. 脳硬膜マクロファージを中心とした新たなせん妄発生機序の解明

    Grant number:22K16600  2022.4 - 2025.3

    日本学術振興会  科学研究費助成事業  若手研究

    佐藤 威仁

      More details

    Authorship:Principal investigator 

    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

    脳を包む髄膜のうち、硬膜組織には近年新たにリンパ管の存在が明らかとなったことや、脳硬膜血管周囲にマクロファージが存在する事が報告され、その生理学的意義に関し検討が行われてきている。マクロファージは貪食能をもつ白血球細胞の一種であり、抗原提示やサイトカイン産生などの炎症反応に関連する細胞である。近年、硬膜の炎症が脳実質に影響を及ぼし行動学的に影響を及ぼす可能を示唆した報告がなされ、脳実質と脳硬膜との相互的な関連が示唆されている。
    本研究では、脳硬膜マクロファージがせん妄発生機序と関連するという仮説を立て、せん妄モデルマウスを作成し、せん妄発生の関連並びに予防、治療に関し検討することを目的とする。