Updated on 2024/09/18

写真a

 
MIYATA Seiko
 
Organization
Graduate School of Medicine Department of Clinical Psychiatry Endowed Chair Designated lecturer
Title
Designated lecturer
Contact information
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Degree 1

  1. 博士（医療技術学） （ 2007.3   名古屋大学 ） 

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Research Interests 2

  1. 脳機能

  2. 睡眠

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Research Areas 2

  1. Others / Others  / 睡眠医学

  2. Life Science / Psychiatry

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Current Research Project and SDGs 2

  1. 睡眠と脳機能との関連

  2. 在宅検査法の開発

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Research History 4

  1. 名古屋大学大学院医学系研究科精神医学分野

    2017.4

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    Country：Japan

  2. 名古屋大学大学院医学系研究科睡眠医学寄附講座

    2014.5 - 2017.3

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    Country：Japan

  3. 中部大学臨床検査技術教育・実習センター　助教

    2012.4 - 2014.4

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    Country：Japan

  4. 中部大学臨床検査技術教育・実習センター　助手

    2010.1 - 2012.3

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    Country：Japan

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Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    - 2007.3

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    Country： Japan

  2. Nagoya University   Faculty of Medicine

    - 2002.3

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    Country： Japan

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Professional Memberships 6

  1. 日本睡眠学会

  2. 日本臨床衛生検査技師会

  3. 日本認知症予防学会

  4. Japanese Academy of Sleep Technology

  5. 日本医用マススペクトル学会

  6. 日本生物学的精神医学会

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Committee Memberships 1

  1. 日本臨床衛生検査技師会   認定認知症領域検査技師制度　試験WG  

    2022.7   

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    Committee type：Academic society

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Papers 115

  1. Phenotypes for general behavior, activity, and body temperature in 3q29 deletion model mice.

    Mori D, Ikeda R, Sawahata M, Yamaguchi S, Kodama A, Hirao T, Arioka Y, Okumura H, Inami C, Suzuki T, Hayashi Y, Kato H, Nawa Y, Miyata S, Kimura H, Kushima I, Aleksic B, Mizoguchi H, Nagai T, Nakazawa T, Hashimoto R, Kaibuchi K, Kume K, Yamada K, Ozaki N

    Translational psychiatry   Vol. 14 ( 1 ) page： 138   2024.3

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Translational Psychiatry  

    Whole genome analysis has identified rare copy number variations (CNV) that are strongly involved in the pathogenesis of psychiatric disorders, and 3q29 deletion has been found to have the largest effect size. The 3q29 deletion mice model (3q29-del mice) has been established as a good pathological model for schizophrenia based on phenotypic analysis; however, circadian rhythm and sleep, which are also closely related to neuropsychiatric disorders, have not been investigated. In this study, our aims were to reevaluate the pathogenesis of 3q29-del by recreating model mice and analyzing their behavior and to identify novel new insights into the temporal activity and temperature fluctuations of the mouse model using a recently developed small implantable accelerometer chip, Nano-tag. We generated 3q29-del mice using genome editing technology and reevaluated common behavioral phenotypes. We next implanted Nano-tag in the abdominal cavity of mice for continuous measurements of long-time activity and body temperature. Our model mice exhibited weight loss similar to that of other mice reported previously. A general behavioral battery test in the model mice revealed phenotypes similar to those observed in mouse models of schizophrenia, including increased rearing frequency. Intraperitoneal implantation of Nano-tag, a miniature acceleration sensor, resulted in hypersensitive and rapid increases in the activity and body temperature of 3q29-del mice upon switching to lights-off condition. Similar to the 3q29-del mice reported previously, these mice are a promising model animals for schizophrenia. Successive quantitative analysis may provide results that could help in treating sleep disorders closely associated with neuropsychiatric disorders.

    DOI： 10.1038/s41398-023-02679-w

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  2. Assessment of cognitive function and sleep-wake rhythms in community-dwelling older adults.

    Okuda M, Noda A, Iwamoto K, Hishikawa N, Miyata S, Yasuma F, Taoka T, Ozaki N, Suhr JA, Miyazaki S

    Sleep and biological rhythms   Vol. 22 ( 1 ) page： 137 - 145   2024.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Sleep and Biological Rhythms  

    Disruption of the circadian rhythm and sleep–wake cycles is a consequence of aging and is associated with the cognitive decline and many neurodegenerative conditions. We investigated the bedtime, wake-up time, sleep timing (midpoint between bedtime and wake-up time), and sleep timing standard deviation (SD) using the actigraphy among 80 consecutive volunteers aged ≥ 60 years. Global cognitive function and executive function of detailed cognitive domains were evaluated using the mini-mental state examination (MMSE) and Wisconsin card sorting test (WCST) and subjective daytime sleepiness was assessed using the Epworth Sleepiness Scale (ESS). The category achievement (CA), total errors (TE), perseverative errors of Nelson (PEN), non-perseverative errors (NPE), and difficulties in maintaining set (DMS) on the WCST were significantly correlated with sleep timing SD (CA: r = − 0.276, p = 0.013, TE: r = 0.311, p = 0.005, PEN: r = 0.241, p = 0.032, NPE: r = 0.250, p = 0.025, DMS: r = 0.235, p = 0.036), but not with the MMSE score. Multiple regression analyses with the stepwise forward selection method including age, ESS score, bedtime, sleep timing, and sleep timing SD, revealed that the ESS score, and sleep timing SD were significant factors related to CA on the WCST (ESS score: β = − 0.322, p = 0.004; sleep timing SD: β = − 0.250, p = 0.022). Assessment of sleep–wake rhythms, daytime sleepiness, and cognitive function using the MMSE and WCST is valuable for the prediction of cognitive decline in the geriatric population.

    DOI： 10.1007/s41105-023-00491-z

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  3. Assessing the Real-World, Long-Term Impact of Lemborexant on Sleep Quality in a Home-Based Clinical Study.

    Miyata S, Iwamoto K, Okada I, Fujimoto A, Kogo Y, Mori D, Amano M, Matsuyama N, Nishida K, Ando M, Taoka T, Naganawa S, Ozaki N

    Nature and science of sleep   Vol. 16   page： 291 - 303   2024

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Nature and Science of Sleep  

    Purpose: Both subjective and objective evaluations are essential for the treatment of insomnia. Lemborexant has been shown to be effective in the long-term based solely on a subjective basis, and no long-term objective measures have been evaluated under natural sleep conditions. Small, lightweight sleep electroencephalogram (EEG) monitor was used, instead of polysomnography, to objectively evaluate sleep at home 4 and 12 weeks after lemborexant treatment. Patients and Methods: Adults and elderly subjects with insomnia disorder, per the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, were enrolled in this open-label, single-arm, single-center trial. Objective and subjective measures of sleep were prospectively assessed. Sleep disturbance, excessive sleepiness, and depressive symptoms were assessed using questionnaires. Results: A total of 45 subjects were screened, of which 33 were enrolled. Paired t-tests were conducted to evaluate changes in sleep variables and compared with the baseline; subjects showed significant improvements in objective sleep efficiency (SE) and subjective sleep parameters at weeks 4 and 12 following treatment with lemborexant. When baseline values were taken into account, a repeated-multivariate analysis of variance (MANOVA) revealed statistically significant changes in the objective measures. Sleep disturbance, excessive sleepiness, and depressive symptoms improved after three months of lemborexant treatment. Conclusion: Furthermore, lemborexant therapy improved nocturnal sleep, when measured objectively using sleep EEG monitoring at home, and improved daytime sleepiness and depressive symptoms in older adults with insomnia disorder.

    DOI： 10.2147/NSS.S448871

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  4. LPS and its relationship with subjective-objective discrepancies of sleep onset latency in patients with psychiatric disorders.

    Kawai K, Iwamoto K, Miyata S, Okada I, Ando M, Fujishiro H, Ando M, Noda A, Ozaki N

    Scientific reports   Vol. 13 ( 1 ) page： 22637   2023.12

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Scientific Reports  

    Subjective–objective discrepancies in sleep onset latency (SOL), which is often observed among psychiatric patients, is attributed partly to the definition of sleep onset. Recently, instead of SOL, latency to persistent sleep (LPS), which is defined as the duration from turning out the light to the first consecutive minutes of non-wakefulness, has been utilized in pharmacological studies. This study aimed to determine the non-awake time in LPS that is most consistent with subjective sleep onset among patients with psychiatric disorders. We calculated the length of non-awake time in 30-s segments from lights-out to 0.5–60 min. The root mean square error was then calculated to determine the most appropriate length. The analysis of 149 patients with psychiatric disorders showed that the optimal non-awake time in LPS was 12 min. On the other hands, when comorbid with moderate or severe obstructive sleep apnea (OSA), the optimal length was 19.5 min. This study indicates that 12 min should be the best fit for the LPS non-awake time in patients with psychiatric disorders. When there is comorbidity with OSA, however, a longer duration should be considered. Measuring LPS minimizes discrepancies in SOL and provides important clinical information.

    DOI： 10.1038/s41598-023-49261-4

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  5. Comparison of Polysomnography, Single-Channel Electroencephalogram, Fitbit, and Sleep Logs in Patients With Psychiatric Disorders: Cross-Sectional Study.

    Kawai K, Iwamoto K, Miyata S, Okada I, Fujishiro H, Noda A, Nakagome K, Ozaki N, Ikeda M

    Journal of medical Internet research   Vol. 25 ( 1 ) page： e51336   2023.12

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Journal of Medical Internet Research  

    Background: Sleep disturbances are core symptoms of psychiatric disorders. Although various sleep measures have been developed to assess sleep patterns and quality of sleep, the concordance of these measures in patients with psychiatric disorders remains relatively elusive. Objective: This study aims to examine the degree of agreement among 3 sleep recording methods and the consistency between subjective and objective sleep measures, with a specific focus on recently developed devices in a population of individuals with psychiatric disorders. Methods: We analyzed 62 participants for this cross-sectional study, all having data for polysomnography (PSG), Zmachine, Fitbit, and sleep logs. Participants completed questionnaires on their symptoms and estimated sleep duration the morning after the overnight sleep assessment. The interclass correlation coefficients (ICCs) were calculated to evaluate the consistency between sleep parameters obtained from each instrument. Additionally, Bland-Altman plots were used to visually show differences and limits of agreement for sleep parameters measured by PSG, Zmachine, Fitbit, and sleep logs. Results: The findings indicated a moderate agreement between PSG and Zmachine data for total sleep time (ICC=0.46; P<.001), wake after sleep onset (ICC=0.39; P=.002), and sleep efficiency (ICC=0.40; P=.006). In contrast, Fitbit demonstrated notable disagreement with PSG (total sleep time: ICC=0.08; wake after sleep onset: ICC=0.18; sleep efficiency: ICC=0.10) and exhibited particularly large discrepancies from the sleep logs (total sleep time: ICC=–0.01; wake after sleep onset: ICC=0.05; sleep efficiency: ICC=–0.02). Furthermore, subjective and objective concordance among PSG, Zmachine, and sleep logs appeared to be influenced by the severity of the depressive symptoms and obstructive sleep apnea, while these associations were not observed between the Fitbit and other sleep instruments. Conclusions: Our study results suggest that Fitbit accuracy is reduced in the presence of comorbid clinical symptoms. Although user-friendly, Fitbit has limitations that should be considered when assessing sleep in patients with psychiatric disorders.

    DOI： 10.2196/51336

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  6. Assessment of cognitive function and sleep-wake rhythms in community-dwelling older adults

    Okuda Masato, Noda Akiko, Iwamoto Kunihiro, Hishikawa Nozomi, Miyata Seiko, Yasuma Fumihiko, Taoka Toshiaki, Ozaki Norio, Suhr Julie A., Miyazaki Soichiro

    SLEEP AND BIOLOGICAL RHYTHMS     2023.9

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： 10.1007/s41105-023-00491

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  7. Evaluating sleep-wake rhythm using a wearable device in patients with mental disorders.

    Miyata S, Iwamoto K, Ozaki N

    Psychiatry and clinical neurosciences   Vol. 77 ( 8 ) page： 419 - 419   2023.8

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Psychiatry and Clinical Neurosciences  

    DOI： 10.1111/pcn.13568

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  8. LONG-TERM EFFICACY OF LEMBOREXANT ON OBJECTIVE SLEEP MEASURES IN CLINICAL PRACTICE

    Miyata Seiko, Iwamoto Kunihiro, Okada Ippei, Fujimoto Akihiro, Kogo Yuki, Amano Manabu, Matsuyama Nao, Ozaki Norio

    SLEEP   Vol. 46   2023.5

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  9. Temporal trajectories of proposed biomarkers in psychiatric-onset prodromal dementia with Lewy bodies: a case report

    Fujishiro Hiroshige, Arafuka Shusei, Ogasawara Kazuyoshi, Iwamoto Kunihiro, Miyata Seiko, Torii Youta, Iritani Shuji, Ozaki Norio

    PSYCHOGERIATRICS   Vol. 23 ( 1 ) page： 196 - 200   2023.1

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Psychogeriatrics  

    DOI： 10.1111/psyg.12922

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  10. Feasibility of a wrist-worn wearable device for estimating mental health status in patients with mental illness.

    Nakagome K, Makinodan M, Uratani M, Kato M, Ozaki N, Miyata S, Iwamoto K, Hashimoto N, Toyomaki A, Mishima K, Ogasawara M, Takeshima M, Minato K, Fukami T, Oba M, Takeda K, Oi H

    Frontiers in psychiatry   Vol. 14   page： 1189765   2023

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Frontiers in Psychiatry  

    Object: Real-world data from wearable devices has the potential to understand mental health status in everyday life. We aimed to investigate the feasibility of estimating mental health status using a wrist-worn wearable device (Fitbit Sense) that measures movement using a 3D accelerometer and optical pulse photoplethysmography (PPG). Methods: Participants were 110 patients with mental illnesses from different diagnostic groups. The study was undertaken between 1 October 2020 and 31 March 2021. Participants wore a Fitbit Sense on their wrist and also completed the State–Trait Anxiety Inventory (STAI), Positive and Negative Affect Schedule (PANAS), and EuroQol 5 dimensions 5-level (EQ-5D-5L) during the study period. To determine heart rate (HR) variability (HRV), we calculated the sdnn (standard deviation of the normal-to-normal interval), coefficient of variation of R-R intervals, and mean HR separately for each sleep stage and the daytime. The association between mental health status and HR and HRV was analyzed. Results: The following significant correlations were found in the wake after sleep onset stage within 3 days of mental health status assessment: sdnn, HR and STAI scores, HR and PANAS scores, HR and EQ-5D-5L scores. The association between mental health status and HR and HRV was stronger the closer the temporal distance between mental health status assessment and HR measurement. Conclusion: A wrist-worn wearable device that measures PPG signals was feasible for use with patients with mental illness. Resting state HR and HRV could be used as an objective assessment of mental health status within a few days of measurement.

    DOI： 10.3389/fpsyt.2023.1189765

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  11. Prevalence of obstructive sleep apnea as assessed by polysomnography in psychiatric patients with sleep-related problems.

    Okada I, Miyata S, Iwamoto K, Fujishiro H, Noda A, Ozaki N

    Sleep & breathing = Schlaf & Atmung   Vol. 26 ( 4 ) page： 1983 - 1991   2022.12

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Sleep and Breathing  

    Purpose: Patients with psychiatric disorders often complain of sleep disturbances and are frequently suspected of obstructive sleep apnea (OSA). However, data regarding sleep problems evaluated by attended polysomnography (PSG) remain limited in this population. We analyzed the results of attended PSG from psychiatric patients with sleep-related problems to determine the prevalence and features of sleep disorders among this population. Methods: We retrospectively investigated the attended PSG results of patients with psychiatric disorders: major depressive disorder, bipolar disorder, neurodevelopmental disorder, schizophrenia, neurocognitive disorder, anxiety disorder, somatic symptom disorder. Results: Of 264 patients, 158 men (60%), mean age was 47 ± 19.9 years. More than half of the patients with major depressive disorder (62%), bipolar disorder (70%), schizophrenia (58%), neurocognitive disorders (55%), and somatic symptom disorder (56%) had OSA. Among the psychiatric patients with OSA, 62% of these patients had moderate to severe OSA. The risk factors for OSA were snoring, male, age, and body mass index. The presence of OSA was not associated with the Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale score, or benzodiazepine, antipsychotic, or antidepressant use. Other sleep disorders were insomnia (19%), central disorders of hypersomnia (8%), restless legs syndrome/periodic limb movement of sleep (8%), rapid eye movement sleep behavior disorder (7%), and central sleep apnea syndrome (3%). Conclusions: PSG revealed that moderate to severe OSA was common in psychiatric patients with or without snoring. Subjective symptoms and psychotropics did not predict OSA. Therefore, PSG is needed to reveal sleep conditions in patients with psychiatric disorders.

    DOI： 10.1007/s11325-022-02566-6

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  12. Polysomnographic characteristics and predictors of positional obstructive sleep apnea in Japanese elderly.

    Miyata S, Otake H, Fujishiro H, Iwamoto K, Noda A, Sone M, Ozaki N

    Sleep and biological rhythms   Vol. 20 ( 3 ) page： 403 - 411   2022.7

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Sleep and Biological Rhythms  

    Sleep problems and obstructive sleep apnea (OSA) increase with age and disturb life in old age. Positional therapy is one option to treat OSA, but the differences in clinical pathophysiology between elderly and other age groups have not been fully investigated. We explored the pathophysiological features of sleep apnea, factors that are independently associated with positional OSA and the prevalence in elderly patients. We studied demographic and polysomnographic data of 85 elderly individuals with OSA (age ≥ 65 years) and 124 non-elderly patients with OSA (age, 20–64 years). The Amsterdam Positional OSA Classification (APOC) was used to evaluate positional OSA. Body mass index (BMI) and Epworth sleepiness scale were both significantly lower in the elderly group than in the non-elderly group, although apnea/hypopnea index (AHI) did not differ between groups. OSA severity affected total sleep time, sleep efficiency, and waking after sleep onset more in the elderly than in the non-elderly. AHI in the lateral position was significantly lower in elderly than in non-elderly, although AHI in the supine position was almost the same between two groups. The distribution of APOC 1 and 2 (lateral sleep effective) was significantly higher in the elderly than in the non-elderly. Relative factors such as BMI, rate of hypopnea, and lowest SpO2 associated with positional OSA in non-elderly groups did not differ significantly among APOC subgroups in elderly patients. Our findings are suggesting that characteristics of the positional OSA is different between elderly and younger-age OSA patients.

    DOI： 10.1007/s41105-022-00385-6

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  13. A Study of Factors Causing Sleep State Misperception in Patients with Depression.

    Kawai K, Iwamoto K, Miyata S, Okada I, Ando M, Fujishiro H, Noda A, Ozaki N

    Nature and science of sleep   Vol. 14   page： 1273 - 1283   2022

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Nature and Science of Sleep  

    Purpose: Sleep state misperception, which is the discrepancy between subjective and objective sleep, is often observed in patients with depression. This phenomenon may delay the remission of depression. Previous studies have focused on the total sleep time (TST) misperception, with many of these studies using actigraphy. Thus, our study investigated depressed patients with the exploratory aim of clarifying factors associated with the sleep state misperception including the wake after sleep onset (WASO) misperception, with their objective sleep additionally evaluated by polysomnography (PSG). Patients and Methods: We conducted a cross-sectional study. Before undergoing overnight PSG monitoring, 40 patients with depression completed questionnaires that included the Beck Depression Inventory (BDI), Epworth sleepiness scale, Temperament and Character Inventory, and the Pittsburgh sleep quality index. Patients were also asked to estimate their subjective sleep duration after they woke up in the morning. Based on this data, we calculated the misperception using the following formula: subjective sleep duration minus objective sleep duration. We compared each factor between negative and positive misperception groups and the multiple regression analysis was performed for TST and WASO misperception, respectively. Results: Although sleep architectures, age, severity of depression and obstructive sleep apnea (OSA) exhibited differences in underestimating or overestimating the WASO, only sex differences were associated with underestimating or overestimating their total sleep time (TST). Moreover, BDI, the severity of OSA, sleep architectures (N1% and N2%), and benzodiazepine (BZD) use were significantly correlated with WASO misperception, whereas only OSA severity was significantly correlated with TST misperception. A subsequent multiple regression analysis demonstrated the BDI was independently correlated with the WASO misperception (β=0.341, p=0.049). Conclusion: In clinical practice, interventions especially for OSA, and the reduction of depressive symptoms are an important method for improving patient sleep perception. Moreover, current results suggest that BZD prescriptions should be avoided as well.

    DOI： 10.2147/NSS.S366774

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  14. FLUID study: study protocol for an open-label, single-centre pilot study to investigate the efFect of Lemborexant on sleep management in Japanese sUbjects aged 50 years and older with Insomnia Disorder.

    Okada I, Iwamoto K, Miyata S, Fujimoto A, Tanaka M, Amano M, Matsuyama N, Taoka T, Naganawa S, Ozaki N

    BMJ open   Vol. 11 ( 11 ) page： e054885   2021.11

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：BMJ Open  

    Introduction Bidirectional associations have been reported between sleep disturbance and both cognitive impairment, including Alzheimer’s disease and amyloid beta-peptide (Aβ) accumulation. These relationships can be explained by the glymphatic system, which acts as a garbage drainage system in the brain. As interstitial fluid dynamics are suggested to increase during sleep, clearance of Aβ can be influenced by sleep disturbance or deprivation. We hypothesised that using lemborexant, an orexin receptor antagonist, to improve sleep quality would also improve the function of the glymphatic system. We plan to examine the effect of lemborexant on sleep quality and the glymphatic system among patients with insomnia disorder. Methods and analysis This pilot study is designed as an open-label, single-arm, single-centre trial. Thirty patients aged 50 years and over with insomnia will be recruited. The participants will take lemborexant (5 mg) at bedtime for 12 weeks and undergo a home-based sleep study at baseline and weeks 4 and 12, as well as MRI examinations to evaluate the glymphatic system at baseline and week 12. The primary outcome will be changes in objective sleep parameters as evaluated using a sleep monitoring system. The secondary outcomes will be changes in subjective sleep parameters. The relationships between changes in sleep parameters and the glymphatic system will be evaluated using diffusion tensor image analysis along the perivascular space, which is called the ALPS-index. Sleep parameters and the ALPS-index will be analysed using a paired t-test or Pearson’s correlation coefficient. Ethics and dissemination The study protocol was approved by Nagoya University Certified Review Board. The findings from this research will be published in peer-reviewed journals and be presented at local, national and international conferences.

    DOI： 10.1136/bmjopen-2021-054885

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  15. Performance of an ambulatory electroencephalogram sleep monitor in patients with psychiatric disorders.

    Miyata S, Iwamoto K, Banno M, Eguchi J, Kaneko S, Noda A, Ozaki N

    Journal of sleep research   Vol. 30 ( 4 ) page： e13273   2021.8

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Journal of Sleep Research  

    Key clinical symptoms observed among individuals with psychiatric disorders include difficulty falling asleep or maintaining sleep, poor sleep quality and nightmares. Those suffering from sleep disorders often present with symptoms of discontent with regard to sleep quality, timing and quantity, and these symptoms have an adverse impact on function and quality of life. A minimally invasive technique would be preferable in patients with psychiatric disorders, who tend to be sensitive to environmental change. Accordingly, we evaluated the performance of Zmachine Insight Plus, an ambulatory electroencephalography sleep monitor, in patients with psychiatric disorders. One hundred and three patients undergoing polysomnography were enrolled in this study. Zmachine Insight Plus was performed simultaneously with polysomnography. Total sleep time, sleep efficiency, wake after sleep onset, rapid eye movement (REM) sleep, light sleep (stages N1 and N2) and deep sleep (stage N3) were assessed. Total sleep time, sleep efficiency, wake after sleep onset, REM sleep duration and non-REM sleep duration of Zmachine Insight Plus showed a significant correlation with those of polysomnography. Lower sleep efficiency and increased frequency of waking after sleep onset, the arousal index and the apnea–hypopnea index on polysomnography were significantly associated with the difference in sleep parameters between the two methods. Among patients with psychiatric disorders who are sensitive to environmental change, Zmachine Insight Plus would be a useful technique to objectively evaluate sleep quality.

    DOI： 10.1111/jsr.13273

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  16. Effects of age and sex on eye movement characteristics.

    Takahashi J, Miura K, Morita K, Fujimoto M, Miyata S, Okazaki K, Matsumoto J, Hasegawa N, Hirano Y, Yamamori H, Yasuda Y, Makinodan M, Kasai K, Ozaki N, Onitsuka T, Hashimoto R

    Neuropsychopharmacology reports   Vol. 41 ( 2 ) page： 152 - 158   2021.6

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Neuropsychopharmacology Reports  

    Abnormal eye movements are often associated with psychiatric disorders. Eye movements are sensorimotor functions of the brain, and aging and sex would affect their characteristics. A precise understanding of normal eye movements is required to distinguish disease-related abnormalities from natural differences associated with aging or sex. To date, there is no multicohort study examining age-related dependency and sex effects of eye movements in healthy, normal individuals using large samples to ensure the robustness and reproducibility of the results. In this study, we aimed to provide findings showing the impact of age and sex on eye movement measures. The present study used eye movement measures of more than seven hundred healthy individuals from three large independent cohorts. We herein evaluated eye movement measures quantified by using a set of standard eye movement tests that have been utilized for the examination of patients with schizophrenia. We assessed the statistical significance of the effects of age and sex and its reproducibility across cohorts. We found that 4-18 out of 35 eye movement measures were significantly correlated with age, depending on the cohort, and that 10 of those, which are related to the fixation and motor control of smooth pursuit and saccades, showed high reproducibility. On the other hand, the effects of sex, if any, were less reproducible. The present results suggest that we should take age into account when we evaluate abnormalities in eye movements.

    DOI： 10.1002/npr2.12163

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  17. Sleep fragmentation and working memory in healthy adults.

    Okuda M, Noda A, Mabuchi S, Iwamoto K, Banno M, Miyata S, Yasuma F, Ozaki N

    Sleep science (Sao Paulo, Brazil)   Vol. 14 ( Spec 2 ) page： 111 - 117   2021.4

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Sleep Science  

    Introduction: Sleep is essential for performing cognitive function in humans. We have hypothesized that sleep fragmentation compared to sleep efficiency may have a negative impact on the working memory. Material and Methods: Twenty-eight healthy adults (18 males and 10 females; mean age 27.8±15.5 years) were enrolled in this study. We measured the total sleep time (TST), sleep efficiency, %stage wakefulness (W), %stage rapid eye movement (REM), %stage N1, %stage N2, %stage N3, wake after sleep onset (WASO), and arousal index using polysomnography. Working memory, executive function, and sustained attention of three domains of cognitive function were evaluated with the number of back task (N-back task), Wisconsin card sorting test (WCST), and continuous performance test-identical pairs (CPT-IP), respectively. Results: The percentage of correct answers on the 2-back task was significantly correlated with %stage REM, %stage N1, and %stage N2 (%stage REM: r=0.505, p=0.006; %stage N1: r=-0.637, p<0.001; %stage N2: r=0.670, p<0.001), and multiple regression analysis including the stepwise forward selection method revealed that %stage N2 was the most significant factor (%stage N2: β=0.670, p<0.001). The percentage of correct answers on the 2-back task was also significantly correlated with TST, sleep efficiency, WASO, and arousal index (TST: r=0.492, p=0.008; sleep efficiency: r=0.622, p<0.001; WASO: r=-0.721, p<0.001; arousal index: r=-0.656, p<0.001), and WASO was the significant factor (β=-2.086, p=0.007). The WCST category achievement and CPT-IP d-prime score were correlated with none of the sleep variables. Conclusion: Increased WASO and a decrease in %stage N2 were associated with worse working memory.

    DOI： 10.5935/1984-0063.20200088

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  18. Effects of long sleep time and irregular sleep-wake rhythm on cognitive function in older people.

    Okuda M, Noda A, Iwamoto K, Nakashima H, Takeda K, Miyata S, Yasuma F, Ozaki N, Shimouchi A

    Scientific reports   Vol. 11 ( 1 ) page： 7039   2021.3

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    Sleep disturbances and cognitive decline are common in older adults. We aimed to investigate the effects of the total sleep time (TST) and sleep–wake rhythm on executive function and working memory in older adults. In 63 older participants, we measured the TST, wake after sleep onset (WASO), and sleep timing (midpoint between bedtime and wake-up time) using actigraphy. Executive function was evaluated with the trail making test B (TMT-B) and Wisconsin card sorting test (WCST). The number of back task (N-back task) was used to measure working memory. Participants with a TST ≥ 8 h had a significantly lower percentage of correct answers (% correct) on the 1-back task than those with a TST < 8 h. The % correct on the 1-back task was significantly correlated with the TST, WASO, and sleep timing. Multiple regression analyses revealed that the TST and sleep timing were significant factors of the % correct on the 1-back task. The TMT-B score was significantly correlated with the sleep timing. Category achievement on the WCST was significantly correlated with the standard deviation of the sleep timing. Therefore, a long sleep time and an irregular sleep–wake rhythm could have adverse effects on executive function and working memory in older people.

    DOI： 10.1038/s41598-021-85817-y

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  19. Consideration for daily preventive measures to lead a healthy and comfortable life

    The Society of Heating, Air-Conditioning and Sanitary Engineers of Japan, Chubu,   Vol. 22 ( 0 ) page： 77 - 80   2021

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    DOI： 10.18948/shasec.22.0_77

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  20. Patient characteristics affecting accurate detection of sleep apnea using a bed sheet-type portable monitor

    Miyata Seiko, Otake Hironao, Ando Motoo, Okuda Masato, Fujishiro Hiroshige, Iwamoto Kunihiro, Noda Akiko, Sone Michihiko, Ozaki Norio

    SLEEP AND BREATHING   Vol. 24 ( 2 ) page： 783 - 790   2020.6

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    DOI： 10.1007/s11325-019-01963-8

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  21. SLEEP MONITORING WITH A SINGLE CHANNEL EEG RECORDER IN PATIENTS WITH PSYCHIATRIC DISORDERS

    Miyata S., Iwamoto K., Banno M., Ito Y., Noda A., Ozaki N.

    SLEEP   Vol. 43   page： A220 - A221   2020.4

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  22. Effects of sleep-disordered breathing and hypertension on cognitive function in elderly adults

    Kato Kazuko, Noda Akiko, Yasuma Fumihiko, Matsubara Yuka, Miyata Seiko, Iwamoto Kunihiro, Miyazaki Soichiro, Ozaki Norio

    CLINICAL AND EXPERIMENTAL HYPERTENSION   Vol. 42 ( 3 ) page： 250 - 256   2020

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    DOI： 10.1080/10641963.2019.1632338

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  23. 認知症と睡眠障害

    宮田 聖子

    日本臨牀   Vol. 78   page： 567 - 571   2020

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  24. 高齢者の不眠、過眠、薬物療法が運転に及ぼす影響と指導法を教えてください

    宮田 聖子

    老年医学   Vol. 58   page： 433 - 436   2020

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  25. Clinical profiles of late-onset psychiatric patients exhibiting incidental REM sleep without atonia

    Fujishiro Hiroshige, Okuda Masato, Iwamoto Kunihiro, Miyata Seiko, Torii Youta, Iritani Shuji, Ozaki Norio

    JOURNAL OF NEURAL TRANSMISSION   Vol. 126 ( 8 ) page： 1095 - 1104   2019.8

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    DOI： 10.1007/s00702-019-02035-7

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  26. CUFF-LESS BLOOD PRESSURE MONITORING DURING SLEEP

    Noda A., Mita Y., Miyata S., Ando M., Okumura T.

    JOURNAL OF HYPERTENSION   Vol. 37   page： E254 - E254   2019.7

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    DOI： 10.1097/01.hjh.0000573244.64731.f2

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  27. Effect of Valvular Regurgitation on Left Ventricular Function in Middle-aged and Elderly

    MIYATA Seiko, NODA Akiko

    Journal of Clinical Physiology   Vol. 49 ( 2 ) page： 89 - 96   2019.5

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    <p>Background: Valvular regurgitation, a degenerative condition, increases in prevalence with age. Its impact on left ventricular (LV) function in the elderly remains unclear, however.</p><p>Objective: The purpose of this study was to characterize the relationship between LV function and valvular regurgitation in middle-aged and elderly.</p><p>Methods: Echocardiography was performed to assess LV systolic and diastolic function in 98 community-dwelling middle-aged and older adults. Mitral regurgitation (MR) and aortic regurgitation (AR) were qualitatively graded from absent or trivial to severe.</p><p>Results: The LV ejection fraction was significantly higher and the deceleration time at the mitral level during rapid filling significantly longer in the MR group than in the non-MR group. The ratio of early diastolic wave peak velocity to mitral annular early diastolic peak velocity was significantly greater in the AR group than in the non-AR group.</p><p>Conclusions: Both MR and AR may play an important role in change in LV systolic and diastolic function, even in cases of mild regurgitation, in middle-aged and elderly.</p>

    DOI： 10.34363/jocp.49.2_89

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  28. EFFECTS OF AROMATHERAPY ON SLEEP AND COGNITIVE FUNCTION IN THE ELDERLY

    Noda Akiko, Funaki Narumi, Hirashita Rie, Nakashima Honoka, Mita Yasuaki, Masato Okuda, Miyata Seiko, Iwamoto Kunihiro, Ozaki Norio, Urakami Katsuya

    SLEEP   Vol. 42   page： .   2019.4

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  29. DIFFERENCES IN SLEEP DURATION AND QUALITY BETWEEN WEEKDAYS AND WEEKENDS IN JAPANESE ADULTS

    Miyata Seiko, Iwamoto Kunihiro, Ando Motoo, Ito Yuki, Noda Aiko, Ozaki Norio

    SLEEP   Vol. 42   page： .   2019.4

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  30. Delayed sleep/wake rhythm and excessive daytime sleepiness correlate with decreased daytime brain activity during cognitive task in university students

    Miyata Seiko, Noda Akiko, Kawai Sayumi, Honda Kumiko, Iwamoto Kunihiro, Ozaki Norio, Miyazaki Soichiro, Kondo Takaharu

    BIOLOGICAL RHYTHM RESEARCH   Vol. 50 ( 2 ) page： 171 - 179   2019.3

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    DOI： 10.1080/09291016.2018.1433467

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  31. Application of eye trackers for understanding mental disorders: Cases for schizophrenia and autism spectrum disorder.

    Shishido E, Ogawa S, Miyata S, Yamamoto M, Inada T, Ozaki N

    Neuropsychopharmacology reports     2019.2

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    DOI： 10.1002/npr2.12046

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  32. 今月の特集1 発症を予測する臨床検査-先制医療で5疾病に立ち向かう! 精神疾患の先制医療

    宮田 聖子, 尾崎 紀夫

    臨床検査   Vol. 63 ( 1 ) page： 37 - 41   2019.1

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    DOI： 10.11477/mf.1542201850

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  33. Relationship between Sleep and Lipid Metabolism

    MIYATA Seiko, NODA Akiko, IWAMOTO Kunihiro, OZAKI Norio

    Oleoscience   Vol. 19 ( 7 ) page： 285 - 290   2019

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    <p>Sleep plays an important role in metabolic regulation and insomnia disorder, short sleep and long sleep are also related with dyslipidemia. Among them especially, numerous evidence suggests that sleep disordered breathing is closely associated with dyslipidemia, hypertension and diabetes, and increases the risk of cardiovascular disease. In addition, in recent years, studies that elucidate the molecular mechanism of dyslipidemia due to sleep disorder by a mass spectrometer is increasing. The relationship between severity and lipid species profile in patients with obstructive sleep apnea has been reported, and the previous study revealed a significant overall shift in lipid metabolism, with higher levels of phospholipids under sleep-restricted conditions. Comprehensive analysis of lipid metabolites using a mass spectrometry further the understanding of sleep/wake regulation and the associated metabolic processes, and will be vital to identify robust biomarkers for disease states and drug efficacy. In this paper, we review epidemiological and mass spectrometric studies on the relationship between sleep and dyslipidemia.</p>

    DOI： 10.5650/oleoscience.19.285

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  34. Very low frequency component of heart rate variability as a marker for therapeutic efficacy in patients with obstructive sleep apnea: Preliminary study

    Noda Akiko, Hayano Junichiro, Ito Nami, Miyata Seiko, Yasuma Fumihiko, Yasuda Yoshinari

    JOURNAL OF RESEARCH IN MEDICAL SCIENCES   Vol. 24 ( 1 ) page： 84   2019

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    DOI： 10.4103/jrms.JRMS_62_18

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  35. Effects of hypnotics on prefrontal cortex activity during a verbal fluency task in healthy male subjects: A near-infrared spectroscopy study

    Tsuruta Yoshiyuki, Iwamoto Kunihiro, Banno Masahiro, Kawano Naoko, Kohmura Kunihiro, Miyata Seiko, Fujishiro Hiroshige, Noda Yukihiro, Noda Akiko, Iritani Shuji, Ozaki Norio

    HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL   Vol. 33 ( 6 ) page： e2678   2018.11

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    DOI： 10.1002/hup.2678

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  36. The effect of short sleep on lipid metabolism in Japanese university students

    Miyata S., Noda A., Iwamoto K., Fujishiro H., Taguchi R., Ozaki N.

    JOURNAL OF SLEEP RESEARCH   Vol. 27   page： .   2018.9

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  37. Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension.

    Matsuoka H, Miyata S, Okumura N, Watanabe T, Hashimoto K, Nagahara M, Kato K, Sobue S, Takeda K, Ichihara M, Iwamoto T, Noda A

    Clinical and experimental hypertension (New York, N.Y. : 1993)     page： 1-5   2018.6

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    DOI： 10.1080/10641963.2018.1481419

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  38. Early diagnosis of Lewy body disease in patients with late-onset psychiatric disorders using clinical history of rapid eye movement sleep behavior disorder and [I-123]-metaiodobenzylguanidine cardiac scintigraphy

    Fujishiro Hiroshige, Okuda Masato, Iwamoto Kunihiro, Miyata Seiko, Torii Youta, Iritani Shuji, Ozaki Norio

    PSYCHIATRY AND CLINICAL NEUROSCIENCES   Vol. 72 ( 6 ) page： 423-434   2018.6

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    DOI： 10.1111/pcn.12651

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  39. BENEFICIAL EFFECTS OF POSITIONAL THERAPY ON COGNITIVE FUNCTION IN ELDERLY PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

    Noda A., Miyata S., Iwamoto K., Ozaki N.

    SLEEP   Vol. 41   page： A209 - A209   2018.4

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    DOI： 10.1093/sleep/zsy061.560

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  40. 睡眠覚醒制御系を用いた精神障害の分類システム構築

    宮田 聖子

    精神医学   Vol. 60   page： 33 - 41   2018

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  41. Effects of lower limb vibrations in the supine position on autonomic activity in healthy adults Reviewed

    Noda A, Tsukano S, Miyata S, Inoue S, Honda K, Yasuma F

    Br J Res   Vol. 4   page： 34   2017.12

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  42. POLYSOMNOGRAPHIC AND MORPHOLOGICAL CHARACTERISTICS IN ELDERLY PATIENTS WITH OBSTRUCTIVE SLEEP APNEA

    Miyata S., Otake H., Noda A., Okuda M., Ando M., Fujishiro H., Iwamoto K., Ozaki N.

    SLEEP MEDICINE   Vol. 40   page： E228-E229   2017.12

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  43. Influence of sleep duration on cortical oxygenation in elderly individuals Reviewed

    Kato K, Miyata S, Ando M, Matsuoka H, Yasuma F, Iwamoto K, Kawano N, Banno M, Ozaki N, Noda A

    Psychiatry Clin Neurosci   Vol. 71   page： 44-51   2017.11

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    DOI： 10.1111/pcn.1246

  44. Nitric Oxide Plasma Level as a Barometer of Endothelial Dysfunction in Factory Workers

    Miyata Seiko, Noda Akiko, Hara Yuki, Ueyama Jun, Kitaichi Kiyoyuki, Kondo Takaaki, Koike Yasuo

    EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES   Vol. 125 ( 10 ) page： 684-689   2017.11

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    DOI： 10.1055/s-0043-110054

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  45. Beneficial effects of CPAP treatment on endothelial function in patients with mild to moderate obstructive sleep apnea. Reviewed

    4. Miyata S, Noda A, Yasuda Y, Kojima MS, Tsukano S, Sugiura T, Koike Y, Otake H

    Cardiovasc Disord Med   Vol. 2   page： 1-4   2017.5

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  46. REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series. Reviewed

    5. Fujishiro H, Okuda M, Iwamoto K, Miyata S, Otake H, Noda A, Iritani S, Ozaki N

    Int J Geriatr Psychiatry   Vol. 32   page： 397-406   2017.4

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  47. REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series

    Fujishiro Hiroshige, Okuda Masato, Iwamoto Kunihiro, Miyata Seiko, Otake Hironao, Noda Akiko, Iritani Shuji, Ozaki Norio

    INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY   Vol. 32 ( 4 ) page： 397-406   2017.4

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    DOI： 10.1002/gps.4477

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  48. EFFECTS OF SLEEP DISORDER AND PHYSICAL ACTIVITY ON COGNITIVE FUNCTION IN OLDER ADULTS

    Noda A., Miyata S., Iwamoto K., Ozaki N.

    SLEEP   Vol. 40   page： A314 - A314   2017.4

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  49. Influence of sleep duration on cortical oxygenation in elderly individuals

    Kato Kazuko, Miyata Seiko, Ando Motoo, Matsuoka Hiroki, Yasuma Fumihiko, Iwamoto Kunihiro, Kawano Naoko, Banno Masahiro, Ozaki Norio, Noda Akiko

    PSYCHIATRY AND CLINICAL NEUROSCIENCES   Vol. 71 ( 1 ) page： 44-51   2017.1

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    DOI： 10.1111/pcn.12464

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  50. Chapter 3: Clinical examination for sleep disorders

    NODA Akiko, MIYATA Seiko

    Japanese Journal of Medical Technology   Vol. 66 ( J-STAGE-2 ) page： 95 - 105   2017

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    DOI： 10.14932/jamt.17j2-13

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  51. 第3章睡眠検査.認知症予防のための検査特集 第6部その他の検査 Reviewed

    野田 明子, 宮田 聖子

    医学検査   Vol. 66   page： 95 - 105   2017

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  52. 睡眠検査 Reviewed

    宮田 聖子

    医学検査   Vol. 66   page： 95 - 105   2017

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  53. Endomyocardial radial strain rate imaging during dobutamine stress echocardiography for the evaluation of contractile reserve in patients with dilated cardiomyopathy Reviewed

    Minoshima M, Noda A, Kobayashi M, Miyata S, Hirashiki A, Okumura T, Izawa H, Ishii H, Kondo T, Murohara T

    J Clin Ultrasound   ( 44 ) page： 555-560   2016.11

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    DOI： 10.1002/jcu.22376

  54. Masked hypertension and morning blood pressure surge in patients with obstructive sleep apnea syndrome Reviewed

    Miyata S, Noda A, Otake H, Yasuda Y.

    J Sleep Disor: Treat Care   Vol. 5   page： 1   2016.2

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    DOI： 10.4172/2325-9639.1000168

  55. The effect of habitual physical training on left ventricular function during exercise by three-dimensional echocardiography Reviewed

    Kojima MS, Noda A, Miyata S, Kojima J, Hara Y, Minoshima M, Matsushita T, Murohara T

    Echocardiography   Vol. 32   page： 1670-1675   2015.11

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    DOI： 10.1111/echo.12934

  56. Impaired cortical oxygenation is related to mood disturbance resulting from three nights of sleep restriction. Reviewed

    Miyata S, Noda A, Iwamoto K, Kawano N, Banno M, Tsuruta Y, Noda Y, Ozaki N.

    Sleep Biol Rhythms     2015.7

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    DOI： doi: 10.1111/sbr.12130

  57. The effect of habitual physical training on left ventricular function during exercise by three-dimensional echocardiography Reviewed

    Kojima MS, Noda A, Miyata S, Kojima J, Hara Y, Minoshima M, Matsushita T, Murohara T

    Echocardiography     2015.3

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    DOI： doi: 10.1111/echo.12934

  58. Smoking acutely impaired endothelial function in healthy college students

    Miyata Seiko, Noda Akiko, Ito Yuki, Iizuka Ryo, Shimokata Kaoru

    ACTA CARDIOLOGICA   Vol. 70 ( 3 ) page： 282 - 285   2015

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    DOI： 10.2143/AC.70.3.3080632

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  59. The effects of acute treatment with paroxetine, amitriptyline, and placebo on equilibrium function in healthy subjects: A double-blind crossover trial. Reviewed

    Miyata S, Noda A, Iwamoto K, Takahashi M, Hara Y, Kojima J, Iidaka T, Ozaki N.

    Int J Psy Clin Pract.   Vol. 18 ( 1 ) page： 32-36   2014

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  60. Effects of a custom-made pillow on sleep and blood pressure circadian rhythm Reviewed

    MiyataS, Noda A

    J Hypertens   Vol. 3   page： 183   2014

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  61. 睡眠ポリグラフ検査における心電図モニターの役割

    宮田 聖子, 野田 明子

    睡眠医療   Vol. 7   page： 406 - 410   2014

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  62. Effects of Aged Garlic Extract on Left Ventricular Diastolic Function and Fibrosis in a Rat Hypertension Model

    Hara Yuki, Noda Akiko, Miyata Seiko, Minoshima Makoto, Sugiurai Mari, Kojima Jun, Takeo Masafumi, Furukawa Mayuko, Cheng Xian Wu, Nagata Kohzo, Murohara Toyoaki

    EXPERIMENTAL ANIMALS   Vol. 62 ( 4 ) page： 305-310   2013.10

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  63. Effect of Aged Garlic Extract on Left Ventricular Diastolic Function and Fibrosis in Rats Model of Hypertension. Reviewed

    Hara Y, Noda A, Miyata S, Minoshima M, Sugiura M, Kojima J, Otake M, Furukawa M, Cheng XW, Nagata K, Murohara T.

    Exp Animal.   Vol. 62   page： 305-310   2013

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  64. Disproportionate change of blood flow between the upper limbs and the lower limbs in healthy young adults during recovery from exercise. Reviewed

    Miyata S, Noda A, Nishikimi N, Yamada A, Murohara T, Komori K.

    Gazzetta Medica Italiana.   Vol. 172 ( 3 ) page： 131-136   2013

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  65. Comparison of oxygen desaturation patterns in children and adults with sleep-disordered breathing. Reviewed

    Hara Y, Noda A, Miyata S, Otake H, Yasuda Y, Okuda M, Koike Y, Nakata S, Nakashima T.

    Am J Otolaryngol.   Vol. 34 ( 5 ) page： 537-540   2013

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  66. Poor sleep quality impaired cognitive performance in older adults. Reviewed

    Miyata S, Noda A, Iwamoto K, Kawano N, Okuda M, Ozaki N.

    J Sleep Res   Vol. 22 ( 5 ) page： 535-541   2013

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  67. Therapeutic strategies for sleep apnea in patients with hypertension and heart failure Reviewed

    Noda A, Miyata S, Yasuda Y

    Pulmonary Medicine   Vol. 2013   page： 814169   2013

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    DOI： doi: 10.1155/2013/814169

  68. Therapeutic strategies for sleep apnea in hypertension and heart failure.

    Noda A, Miyata S, Yasuda Y

    Pulmonary medicine   Vol. 2013   page： 814169   2013

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    DOI： 10.1155/2013/814169

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  69. 心房細動と睡眠呼吸障害

    宮田 聖子, 野田 明子

    睡眠医療   Vol. 7   page： 272 - 275   2013

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  70. Rapid eye movement (REM) sleep: New research

    Noda A.

    Rapid Eye Movement Sleep: New Research     page： 73-83   2012.3

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  71. The effects of the prone position on the physiological function in healthy students. Reviewed

    Miyata S, Noda A, Fujii Y, Maekawa A, Okuda M, Nakazaki C, Otake H, Nakata S, Yasuma F, Koike Y, Shimokata K, Nakashima T, Hinohara S.

    Open Gen Intern Med J.   Vol. 5   page： 9-12   2012

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  72. The effects of the prone position on the physiological function in healthy students. Reviewed

    Miyata S, Noda A, Fujii Y, Maekawa A, Okuda M, Nakazaki C, Otake H, Nakata S, Yasuma F, Koike Y, Shimokata K, Nakashima T, Hinohara S

    Open Gen Intern Med J   Vol. 5   page： 9-12   2012

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  73. RELATIONSHIP BETWEEN SLEEP DURATION AND CARDIO-ANKLE VASCULAR INDEX IN HEALTHY YOUNG ADULTS

    Noda A., Miyata S.

    SLEEP   Vol. 35   page： A317 - A317   2012

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  74. The ratio of adiponectin to homeostasis model assessment of insulin resistance is a powerful index of each component of metabolic syndrome in an aged Japanese population: Results from the KING Study

    Nakatochi Masahiro, Miyata Seiko, Tanimura Daisuke, Izawa Hideo, Asano Hiroyuki, Murase Yosuke, Kato Ryuji, Ichihara Sahoko, Naruse Keiko, Matsubara Tatsuaki, Honda Hiroyuki, Yokota Mitsuhiro

    DIABETES RESEARCH AND CLINICAL PRACTICE   Vol. 92 ( 3 ) page： e61 - 5   2011.6

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    DOI： 10.1016/j.diabres.2011.02.029

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  75. Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population.

    Tanimura D, Shibata R, Izawa H, Hirashiki A, Asano H, Murase Y, Miyata S, Nakatochi M, Ouchi N, Ichihara S, Yasui K, Yoshida T, Naruse K, Matsubara T, Yokota M

    European journal of human genetics : EJHG   Vol. 19 ( 3 ) page： 262 - 9   2011.3

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    DOI： 10.1038/ejhg.2010.201

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  76. Monitoring sleep-wake rhythm with actigraphy in patients on CPAP therapy. Reviewed

    Otake M, Miyata S, Noda A, Koike Y, Hara Y, Sugiura M, Minoshima M, Kojima J, Nakata S, Nakashima T.

    Respiration   Vol. 82   page： 136-141   2011

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  77. Monitoring Sleep-Wake Rhythm with Actigraphy in Patients on Continuous Positive Airway Pressure Therapy

    Otake Masafumi, Miyata Seiko, Noda Akiko, Koike Yasuo, Hara Yuki, Sugiura Mari, Minoshima Makoto, Kojima Jun, Nakata Seiichi, Nakashima Tsutomu

    RESPIRATION   Vol. 82 ( 2 ) page： 136 - 41   2011

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    DOI： 10.1159/000321238

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    Scopus

    PubMed

  78. ONE NIGHT SLEEP RESTRICTION IMPAIRS THE CORTICAL OXYGENATION RESPONSES

    Miyata S., Noda A., Ito M., Iwamoto K., Ozaki N.

    EUROPEAN PSYCHIATRY   Vol. 26   page： .   2011

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    Web of Science

  79. Relation of polymorphisms of the adiponectin gene to components of metabolic syndrome in a population-based study in Japan

    Tanimura D., Shibata R., Izawa H., Asano H., Hirashiki A., Miyata S., Nakatochi M., Naruse K., Matsubara T., Yokota M.

    EUROPEAN HEART JOURNAL   Vol. 31   page： 1006-1006   2010.9

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    Web of Science

  80. 健常成人における熟成にんにくの血管内皮機能へ及ぼす影響

    宮田 聖子, 野田 明子, 永井 万由佳, 大嶽 正文, 上山 純, 古池 保雄

    日本臨床生理学会雑誌 = Japanese journal of applied physiology   Vol. 40 ( 2 ) page： 103 - 108   2010.4

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    CiNii Research

  81. Insufficient sleep impairs driving performance and cognitive function. Reviewed

    Miyata S, Noda A, Ozaki N, Hara Y, Minoshima M, Iwamoto K, Takahashi M, Iidaka T, Koike Y

    Neurosci Lett   Vol. 469   page： 229-233   2010

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  82. EFFECT OF SLEEP DISORDER ON CARDIOVASCULAR FUNCTION IN THE ELDERLY

    Nakazaki C., Noda A., Yamada S., Miyata S., Koike Y.

    SLEEP   Vol. 33   page： A353 - A354   2010

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  83. SLEEP FRAGMENTATION AND HYPOXIA IMPAIR ENDOTHELIAL FUNCTION IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME

    Noda A., Miyata S., Nakazaki C., Nakata S., Koike Y.

    SLEEP   Vol. 33   page： A118 - A118   2010

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    Web of Science

  84. Impact of microarousal associated with increased negative esophageal pressure in sleep-disordered breathing. Reviewed

    Sukegawa M, Noda A, Yasuda Y, Nakata S, Sugiura T, Miyata S, Honda K, Hasegawa Y, Nakashima T, Koike Y

    Sleep Breath   Vol. 13   page： 369-373   2009

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  85. Sleep and lifestyle habits in morning and evening types of human circadian rhythm. Reviewed

    Sukegawa M, Noda A, Morishita Y, Ohi H, Miyata S, Honda K, Maeno N, Ozaki N, Koike Y

    Biological Rhythm Research   Vol. 40   page： 121-127   2009

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  86. Aortic Pressure Augmentation as a Marker of Cardiovascular Risk in Obstructive Sleep Apnea Syndrome

    NODA Akiko, NAKATA Seiichi, FUKATSU Hiroshi, YASUDA Yoshinari, MIYAO Etsuko, MIYATA Seiko, YASUMA Fumihiko, MUROHARA Toyoaki, YOKOTA Mitsuhiro, KOIKE Yasuo

    Hypertens Res   Vol. 31 ( 6 ) page： 1109 - 1114   2008.6

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    CiNii Research

  87. Evaluation of left ventricular function in healthy subjects during exercise using three-dimensional echocardiography

    SUGIURA Mari, NODA Akiko, GOTOH Yumi, MINOSHIMA Makoto, HARA Yuki, MIYATA Seiko, ITOH Rieko, IINO Shigeo, NAGATA Kohzou, KOIKE Yasuo

    Choonpa Igaku   Vol. 35 ( 4 ) page： 409 - 414   2008.2

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japan Society of Ultrasonics in Medicine  

    <B>Purpose</B>: Three-dimensional (3D) echocardiography is useful for the accurate evaluation of left ventricular (LV) function, but its reliability during exercise remains unclear. We conducted an investigation to determine whether 3D echocardiography was practicable for evaluating LV function during exercise. <B>Subjects and Methods</B>: We studied 18 healthy subjects (12 males, 6 females: 22.7±1.8 years). All subjects underwent supine bicycle ergometer exercise tests. We compared stroke volume index (SVI, stroke volume / body surface area), cardiac index (CI, cardiac output / body surface area), and LV ejection fraction (LVEF) during exercise using pulsed wave Doppler (PWD) and two-dimensional (2D) and 3D echocardiography. The inter-observer and intra-observer variations were measured repeatedly during exercise. <B>Results</B>: The SVI and CI measured by 3D echocardiography continued to increase during exercise, and these were accompanied by heart rate elevation. The inter-observer and intra-observer variations in LV volume measured by 3D echocardiography were better than those for PWD and 2D echocardiography. We could evaluate the dyssynchrony at maximum exercise using 3D echocardiography. <B>Conclusion</B>: 3D echocardiography is a reproducible tool that could feasibly be used for the evaluation of LV function during exercise.

    DOI： 10.3179/jjmu.35.409

    Scopus

    CiNii Research

  88. Aortic pressure augmentation as a marker of cardiovascular risk in obstructive sleep apnea syndrome. Reviewed

    Noda A, Nakata S, Fukatsu H, Yasuda Y, Miyao E, Miyata S, Yasuma F, Murohara T, Yokota M, Koike Y.

    Hypertens Res   Vol. 31   page： 1109-1114   2008

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  89. Continuous Positive Airway Pressure Improves Daytime Baroreflex Sensitivity and Nitric Oxide Production in Patients with Moderate to Severe Obstructive Sleep Apnea Syndrome

    NODA Akiko, NAKATA Seiichi, KOIKE Yasuo, MIYATA Seiko, KITAICHI Kiyoyuki, NISHIZAWA Takao, NAGATA Kohzo, YASUMA Fumihiko, MUROHARA Toyoaki, YOKOTA Mitsuhiro

    Hypertens Res   Vol. 30 ( 8 ) page： 669 - 676   2007.8

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  90. Obstructive sleep apnea syndrome adversely affects on cerebral blood flow

    Hara Yuhki, Noda Akiko, Miyata Seiko, Minoshima Makoto, Sukegawa Mayo, Sugiura Mari, Iwami Aki, Adachi Yuki, Iidaka Tetsuya, Ozaki Norio, Koike Yasuo

    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY   Vol. 49 ( 9 ) page： 321A-321A   2007.3

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    Web of Science

  91. OE-299 Myocardium Strain during Dobutamine Stress Echocardiography Discriminate Ischemic Heart Disease from Dilated Cardiomyopathy(Echo/Doppler-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

    Miyata Seiko, Noda Akiko, Asano Hiroyuki, Hirashiki Akihiro, Kobayashi Kazumasa, Yamada Takashi, Kataoka Hiroki, Harada Kenji, Nishizawa Takao, Murase Yosuke, Unno Kazumasa, Isobe Satoshi, Iino Shigeo, Izawa Hideo, Nagata Kohzo, Inden Yoshiya, Murohara Toyoaki, Yokota Mitsuhiro, Koike Yasuo

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 71 ( 0 ) page： 225 - 226   2007.3

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  92. OE-298 Assessment of Regional Myocardial Dysfunction in Hypertrophic Cardiomyopathy Using Endomyocardial and Epimyocardial Radial Strain Imaging(Echo/Doppler-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

    Minoshima Makoto, Noda Akiko, Miyata Seiko, Iwami Aki, Hara Yuhki, Sugiura Mari, Nishizawa Takao, Izawa Hideo, Iino Shigeo, Murohara Toyoaki, Yokota Mitsuhiro, Koike Yasuo

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 71 ( 0 ) page： 225   2007.3

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    CiNii Research

  93. Follow-up for Patients with Obstructive Sleep Apnea Syndrome using A Portable Recording Device

    Miyata Seiko, Noda Akiko, Honda Kumiko, Nakata Seiichi, Suzuki Keisuke, Nakashima Tsutomu, Koike Yasuo

    Nagoya Journal of Medical Science   Vol. 69 ( 1 ) page： 37 - 43   2007.1

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    Publishing type：Research paper (scientific journal)   Publisher：名古屋大学  

    A home screening device, LT-200, can record data on both breathing conditions and body positions during sleep for up to 3 consecutive days in patients with obstructive sleep apnea (OSAS). We investigated the usefulness of the LT-200 device for follow-up of OSAS. Eighteen patients (age 51.0±10.8 years, mean±SD) were enrolled in this study. Standard polysomnography (PSG) was performed on all patients. The number of apnea/hypopnea episodes per hour (apnea/hypopnea index: AHI), the total time that nocturnal oxygen saturation was <90% (oxygen desaturation time: ODT), and the minimum oxygen saturation during sleep (lowest Spo_2) were calculated. We used the LT-200 and PSG to evaluate any improvement in the data obtained after auto-continuous positive airway pressure (auto-CPAP) therapy. AHI was also measured using the LT-200 in three sleep positions to evaluate the efficacy of the lateral position. AHI, ODT, and lowest Spo_2 values did not differ significantly between the PSG and LT-200 recordings on the control and therapy nights. The LT-200 recordings showed that AHI, ODT, and lowest Spo_2 tended to be better on the second night of auto-CPAP therapy than on the first. AHI was significantly lower in the right and left lateral sleep positions than that in the supine position. Our findings suggest that since the LT-200 device provides important information about the severity of OSAS, the efficacy of auto-CPAP therapy, and body position under unattended conditions in the home. It may prove to be a useful tool for following up patients.

    DOI： 10.18999/nagjms.69.1-2.37

  94. Follow-up for patients with obstructive sleep apnea syndrome using a portable recording device. Reviewed

    Miyata S, Noda A, Honda K, Nakata S, Suzuki K, Nakashima T, Koike Y

    Nagoya J Med Sci   Vol. 69   page： 37-43   2007

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  95. Influence of nasal resistance on initial acceptance of continuous positive airway pressure in treatment for obstructive sleep apnea syndrome. Reviewed

    Sugiura T, Noda A, Nakata S, Yasuda Y, Soga T, Miyata S, Nakai S, Koike Y

    Respiration   Vol. 74   page： 56-60   2007

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  96. Continuous positive airway pressure improves daytime baroreflex sensitivity and nitric oxide production in patients with moderate to severe obstructive sleep apnea syndrome. Reviewed

    Noda A, Nakata S, Koike Y, Miyata S, Kitaichi K, Nishizawa T, Nagata K, Yasuma F, Murohara T, Yokota M

    Hypertens Res   Vol. 30   page： 669-676   2007

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  97. Daytime polysomnography for early diagnosis and treatment of patients with suspected sleep-disordered breathing. Reviewed

    Miyata S, Noda A, Nakata S, Yagi H, Yanagi E, Honda K, Sugiura T, Nakai S, Nakashima T, Koike Y

    Sleep Breath   Vol. 11   page： 109-115   2007

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  98. Assessment for severity of sleep-disordered breathing in children

    Hara Y., Noda A., Nakata S., Miyata S., Honda K., Minoshima M., Sugiura M., Nakashima T., Koike Y.

    SLEEP   Vol. 30   page： A77 - A78   2007

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    Web of Science

  99. Comprehensive approaches to identification of susceptibility genes for myocardial infarction

    Yokota M., Miyata S., Asano H., Izawa I., Nagata K.

    RECENT ADVANCES IN CARDIOVASCULAR DISEASE: PROCEEDINGS OF THE 13TH WORLD CONGRESS HEART DISEASE     page： 75-+   2007

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    Web of Science

  100. The role of actigraph for cpap therapy followup in patients with sleep-disordered breathing

    Ohtake M., Noda A., Kojima J., Nakata S., Hara Y., Adati Y., Miyata S., Koike Y.

    SLEEP   Vol. 30   page： A174 - A174   2007

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    Web of Science

  101. 食塩感受性高血圧ラットの高血圧進行過程における左心機能評価

    原 祐樹, 野田 明子, 宮田 聖子, 美濃島 慎, 杉浦 真里, 小島 隼, 大嶽 正文, 加藤 まゆ子, 永田 浩三, 古池 保雄

    超音波検査技術抄録集   Vol. 32 ( 0 ) page： 214 - 214   2007

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    Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：一般社団法人 日本超音波検査学会  

    DOI： 10.11272/jssabst.32.0_214_2

    CiNii Research

  102. Sex differences in the relationships between electrocardiographic abnormalities and the extent of left ventricular hypertrophy by echocardiography. Reviewed

    Ochi H, Noda A, Miyata S, Skegawa M, Iwase M, Koike Y, Ito R, Yamada H, Takamatsu J, Yokota M

    Ann Noninvasive Electrocardiol   Vol. 11   page： 222-229   2006.7

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  103. Reduced nasal resistance after conventional tonsillectomy in obstructive sleep apnea patients

    Nakata S., Noda A., Miyata S., Sugiura T., Morinaga M., Nakashima T.

    SLEEP   Vol. 29   page： A174 - A175   2006

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    Web of Science

  104. The predictor for evaluating the efficacy of the lateral sleeping position

    Soga T., Noda A., Nakata S., Sugiura T., Miyata S., Iwami A., Sukegawa M., Adachi Y., Nakai S., Koike Y.

    SLEEP   Vol. 29   page： A176 - A177   2006

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    Web of Science

  105. The influence of insufficient sleep on cerebral blood volume

    Miyata S., Noda A., Adachi Y., Okuda M., Hara Y., Minoshima M., Sukegawa M., Iidaka T., Ozaki N., Koike Y.

    SLEEP   Vol. 29   page： A116 - A116   2006

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  106. Sleeping and life habits in morning and evening types of sleep-wake rhythm

    Kato H., Noda A., Miyata S., Morishita Y., Adachi Y., Iwami A., Sukegawa M., Maeno N., Ozaki N., Koike Y.

    SLEEP   Vol. 29   page： A57 - A57   2006

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    Web of Science

  107. Sleep-disordered breathing and heart rate variability in hemodialysis patient

    Adachi Y., Soga T., Noda A., Sugiura T., Miyata S., Sukegawa M., Yoshizaki S., Tsuruta Y., Nakai S., Koike Y.

    SLEEP   Vol. 29   page： A311 - A311   2006

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  108. Assessment of Plasma NO in Patients with Diabetes Mellitus(Atherosclerosis, Clinical 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)

    Miyata Seiko, Noda Akiko, Ando Akitada, Kitaichi Kiyoyuki, Izawa Hideo, Nagata Kouzo, Koike Yasuo, Yokota Mitsuhiro

    Circulation journal : official journal of the Japanese Circulation Society   Vol. 69 ( 0 ) page： 384   2005.3

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  109. Assessment of Plasma NO in Patients with Life-Style Disease

    MIYATA Seiko, NODA Akiko, ANDO Akitada, YOSHIMURA Atsuko, UEYAMA Jun, KITAICHI Kiyoyuki, KUROKI Shoko, SUKEGAWA Mayo, KOIKE Yasuo, YOKOTA Mitsuhiro

      Vol. 35 ( 1 ) page： 39 - 43   2005.2

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    CiNii Research

  110. The effects of tonsillectomy and nasal surgery respectively on same OSAHS patients

    Nakata S, Noda A, Miyata S, Nakashima T

    SLEEP   Vol. 28   page： A199 - A200   2005

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    Web of Science

  111. Long-term nasal continuous positive airway pressure treatment decreases pulse wave velocity in patients with obstructive sleep apnea syndrome

    Noda A, Sugiura T, Miyata S, Kitaichi K, Nakata S, Kuroki S, Sukegawa M, Nakai S, Yasuma F, Koike Y

    CIRCULATION   Vol. 110 ( 17 ) page： 607-607   2004.10

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  112. REM sleep is impaired by a small amount of alcohol in young women sensitive to alcohol. Reviewed

    Miyata S, Noda A, Ito N, Atarashi M, Yasuma F, Morita S, Koike Y

    Intern Med   Vol. 43   page： 679-684   2004

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  113. Home screening device for follow-up of continuous positive airway pressure therapy in patients with obstructive sleep apnea syndrome

    Miyata S, Noda A, Nakata S, Honda K, Yanagi E, Nakashima T, Yasuda Y, Sugiura T, Nakai S, Koike Y

    SLEEP   Vol. 27   page： 191 - 191   2004

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    Web of Science

  114. Impaired REM sleep by alcohol ingestion and alcohol sensitivity in young women

    Miyata S, Noda A, Ito N, Iwami A, Atarshi M, Morishita Y, Sukegawa M, Kuroki S, Ochi H, Koike Y

    SLEEP   Vol. 27   page： 39 - 39   2004

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  115. Daytime polysomnography for early detection of severe obstructive sleep apnea syndrome

    Miyata S, Noda A, Nakata S, Atarashi M, Honda K, Koike Y

    SLEEP   Vol. 26   page： A245-A245   2003.5

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    Web of Science

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To the head of Papers.▲

Books 11

  1. 学校におけるメンタルヘルス教育の進め方

    宮田聖子, 岩本邦弘, 尾崎紀夫（ Role： Joint author ,  第2部第1章⑥睡眠・覚醒障害）

    大修館書店  2023  （ ISBN:978-4-469-26963-5 ）

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    Language：Japanese

  2. こころとからだの健康サポートテキスト

    野田明子, 宮田聖子, 安間文彦（ Role： Joint author ,  2.在宅における睡眠検査と睡眠指導）

    岐阜県精神保健福祉協会  2023 

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    Language：Japanese

  3. 睡眠の質と脂質代謝

    宮田聖子, 岩本邦弘, 野田明子, 尾崎紀夫（ Role： Joint author）

    NTS Inc.  2022.6  （ ISBN:978-4-86043-784-8 ）

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    Total pages：812   Language：Japanese

  4. 高齢社会における人と自動車 Reviewed

    宮田聖子, 尾崎紀夫（ Role： Joint author ,  2.5　運転中の体調急変　2.5.1　睡眠障害）

    コロナ社  2021.1  （ ISBN:978-4-339-02772-3 ）

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    Total pages：240   Language：Japanese Book type：Scholarly book

  5. メディカルスタッフ専門基礎科目シリーズ 精神医学　第9章睡眠・覚醒障害

    宮田聖子, 藤城弘樹（ Role： Joint author）

    理工図書  2018.8  （ ISBN:4844608770 ）

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    Language：Japanese Book type：Textbook, survey, introduction

  6. 3）PSGの準備・手順・較正　1. 睡眠ポリグラフ検査(PSG)の基礎的知識 改訂版臨床睡眠検査マニュアル(日本睡眠学会 編)

    野田明子, 宮田聖子（ Role： Joint author）

    ライフ・サイエンス  2015.9  （ ISBN:978-4-89801-527-8 ）

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    Language：Japanese Book type：Scholarly book

  7. メディカルサイエンス　臨床化学検査学・8 ホルモン

    宮田聖子, 野田明子, 古川圭子（ Role： Joint author）

    近代出版  2014.1 

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    Language：Japanese

  8. Rapid Eye Movement Sleep: New Research/Rapid Eye Movement (REM) Sleep: New Research

    （ Role： Joint author）

    Nova Science Publishers  2013 

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    Language：English

  9. Rapid eye movement (REM) sleep: New research

    Noda A., Miyata S., Ozaki N.（ Role： Joint author）

    Rapid Eye Movement Sleep: New Research  2012.3  （ ISBN:9781620812921 ）

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    Language：Japanese

    The electroencephalogram (EEG) during rapid eye movement (REM) sleep are characterized by fast rhythms and theta waves: mixed with distinctive saw-tooth waves, some hallmark of REM sleep is presence of rapid eye movements in all directions, the marked diminution or absence of muscle activities in the chin electromyography (EMG) and further reduction of responsiveness to stimulation. REM sleep is triggered by cholinoceptive and/or cholinergic "REM-on" cells, and terminated by aminergic (noradrenergic and serotonergic) inhibitory "REM-off" cells. Two processes participate in sleep regulation, namely, a homeostatic mechanism depending on sleep debt and the circadian system that regulates sleep induction and wakefulness. The firing rate of the suprachiasmatic nuclei (SCN) of the hypothalamus decreases in the transition from NREM to REM sleep, as shown by the simultaneous recording of EEG activity and SCN electrical activity. In healthy subjects, REM sleep decreased, slow wave sleep increased, sleep-onset latency decreased and late-night disturbance of sleep increased with increasing doses of alcohol. Sleep efficiency and total sleep time are generally higher in patients with behaviourally induced insufficient sleep syndrome (BIISS) than in patient with obstructive sleep apnea syndrome (OSAS) or narcolepsy. Compared to narcolepsy, patients with BISS tend to have less REM sleep, less stage 1 sleep, and more slow wave sleep on PSG. The multiple sleep latency test (MSLT) is essential in documenting pathological sleepiness and when diagnosing narcolepsy. The presence of two sleep onset REMs (SOREMPs) in four or five nap studies and sleep onset latency of less than 8 minutes strongly suggests a diagnosis of narcolepsy. One night of insufficient sleep involved in the changes of cortical oxygenation responses to brain activation as well as the deterioration of daytime cognitive function and driving performance. Sleep is a critical aspect of the pathophysiology and treatment of depression. Depression is characterized by a decrease of REM sleep latency and an increase of REM density. Given the relations between excessive daytime sleepiness/insomnia, traffic and industrial accident, life-threatening events, and cognitive and memory problems, an understanding of the sleep quality (REN/NREM) on psychiatric function is important for health practitioners. © 2012 by Nova Science Publishers, Inc. All rights reserved.

    Scopus

  10. 基礎からの睡眠医学・アクチグラフィ

    宮田聖子, 野田明子（ Role： Joint author）

    名古屋大学出版会  2010 

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    Language：Japanese

  11. Daytime polysomnography and portable recording device for diagnosis and CPAP therapy in patients with obstructive sleep apnea syndrome

    （ Role： Joint author）

    [s.n.]  2007 

    　More details

    Language：Japanese

    CiNii Books

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To the head of Books.▲

MISC 1

  1. Temporal trajectories of proposed biomarkers in psychiatric-onset prodromal dementia with Lewy bodies: a case report.

    Fujishiro H, Arafuka S, Ogasawara K, Iwamoto K, Miyata S, Torii Y, Iritani S, Ozaki N

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society   Vol. 23 ( 1 ) page： 196 - 200   2023.1

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    Language：English   Publisher：Psychogeriatrics  

    DOI： 10.1111/psyg.12922

    Scopus

    PubMed

To the head of MISC.▲

Presentations 52

  1. 軽度認知障害と睡眠指標との関係

    古田万奈, 野田明子, 武田祥也, 岩本邦弘, 奥田将人, 武田湖州恵, 河合敬太, 宮田聖子, 宮崎総一郎, 安間文彦

    日本睡眠学会第48回定期学術集会  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Oral presentation (general)  

  2. 在宅での睡眠時異常行動評価のための検査法開発

    宮田聖子, 岩本邦弘, 藤城弘樹

    日本睡眠学会第48回定期学術集会  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

  3. 日本人成人における平日と休日の睡眠時間・睡眠構築の違いに関する検討 International conference

    宮田聖子, 岩本邦弘, 河合敬太, 安藤元郎, 藤城弘樹, 野田明子, 尾崎紀夫, 池田匡志

    日本睡眠学会第48回定期学術集会  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Poster presentation  

  4. 精神疾患患者の睡眠状態誤認を標的とした最適な客観的入眠潜時の開発

    河合敬太, 岩本邦弘, 宮田聖子, 藤城弘樹, 岡田一平, 安藤元郎, 野田明子, 尾崎紀夫, 池田匡志

    日本睡眠学会第48回定期学術集会  2024.7 

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    Event date： 2024.7

    Language：Japanese   Presentation type：Oral presentation (general)  

  5. Impact of hypertension and sleep-disordered breathing on cognitive decline in older adults International conference

    Noda A, Okuda M, Iwamoto K, Miyata S, Yasuma F

    SLEEP2024  2024.6 

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    Event date： 2024.6

    Language：English   Presentation type：Poster presentation  

  6. The influence of daily rest and activity on mental health among Japanese adults during the COVID-19 pandemic International conference

    Miyata S, Iwamoto K, Kawai K, Fujishiro H, Ozaki N, Ikeda M

    SLEEP2024  2024.6 

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    Event date： 2024.6

    Language：English   Presentation type：Poster presentation  

  7. Comparison of various sleep measurement devices in psychiatric patients International conference

    Kawai K, Iwamoto K, Miyata S, Okada I, Fujishiro H, Ando M, Noda A, Ozaki N, Ikeda M

    SLEEP2024  2024.6 

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    Event date： 2024.6

    Language：English   Presentation type：Poster presentation  

  8. Investigation of the Long-term Effects of Lemborexant on Objective Sleep Measures Using a Miniature Electroencephalogram International conference

    Miyata S, Okada I, Iwamoto K, Fujimoto A, Kogo Y, Amano M, Matsuyama N, Ozaki N, Ikeda M

    CINP2024  2024.5 

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    Event date： 2024.5

    Language：English   Presentation type：Poster presentation  

  9. Association between sleep habits and mental health in Japanese workers during the COVID-19pandemic International conference

    Miyata S, Iwamoto K

    East-Asia Sleep Forum combined with the 13th Sleep Respiration Forum  2024.4 

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    Event date： 2024.4

    Language：English   Presentation type：Oral presentation (general)  

  10. PSGからわかる不整脈

    宮田聖子

    第4回日本睡眠検査学会学術集会  2023.11 

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    Event date： 2023.11

    Language：Japanese   Presentation type：Public lecture, seminar, tutorial, course, or other speech  

  11. ライフサイクルと睡眠障害-認知症予防- Invited

    宮田聖子, 岩本邦弘, 野田明子

    第12回日本認知症予防学会学術集会  2023.9.16 

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    Event date： 2023.9

    Language：Japanese  

  12. 小型脳波計を用いたレンボレキサントの客観的睡眠指標への長期的な影響の検討

    宮田聖子, 岡田一平, 岩本邦弘, 藤本明浩, 向後由貴, 天野学, 松山奈央, 尾崎紀夫, 池田匡志

    日本睡眠学会第45回定期学術集会  2023.9 

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    Event date： 2023.9

    Language：Japanese  

  13. Long-term efficacy of lemborexant on objective sleep measures in clinical practice

    Miyata S, Iwamoto K, Okada I, Fujimoto A, Kogo Y, Amano M, Matsuyama N, Ozaki N

    SLEEP2023  2023.6 

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    Event date： 2023.6

    Language：English  

  14. Medical scientists’ education and participation in dementia care in Japan

    Miyata S, Noda A, Fukazawa K, Ozaki N

    35th World Congress of Biomedical Laboratory Science & 60th Conference of the Korean Association of Medical Technologists 

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    Event date： 2022.10

    Language：English   Presentation type：Oral presentation (general)  

  15. 勤労者における睡眠習慣と精神症状との関連

    宮田聖子, 岩本邦弘, 河合敬太, 安藤元郎, 尾崎紀夫

    日本睡眠学会第47回定期学術集会 

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    Event date： 2022.6

    Language：Japanese   Presentation type：Oral presentation (general)  

  16. 睡眠障害評価への新たなアプローチ：ウェアラブル筋電計による在宅検査

    宮田聖子, 岩本邦弘, 藤城弘樹, 野田明子, 尾崎紀夫.

    日本睡眠学会第47回定期学術集会 

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    Event date： 2022.6

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

  17. 精神科診療におけるウェアラブルデバイスを用いた睡眠評価

    宮田聖子, 岩本邦弘, 尾崎紀夫

    日本睡眠学会第46回定期学術集会  2021.9 

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    Event date： 2021.9

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

  18. 高齢者における睡眠モニタリング Invited

    宮田聖子, 岩本邦弘, 野田明子, 尾崎紀夫

    第9回日本認知症予防学会学術集会  2019.10 

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    Event date： 2019.10

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

  19. 若年健常者における脂質メタボローム解析

    宮田聖子, 三田庸暁, 野田明子, 奥田将人, 尾崎紀夫

    第19回愛知県医学検査学会 

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    Event date： 2019.7

    Language：Japanese   Presentation type：Oral presentation (general)  

  20. 小型脳波計による精神障害患者の睡眠評価

    宮田聖子, 岩本邦弘, 阪野正大, 安藤元郎, 伊藤佑樹, 野田明子, 尾崎紀夫

    第41回日本生物学的精神医学会 

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    Event date： 2019.6

    Language：Japanese   Presentation type：Poster presentation  

  21. 小型脳波計を用いた健常成人における休日を含む1週間の睡眠に関する比較検討

    宮田聖子, 岩本邦弘, 阪野正大, 安藤元郎, 伊藤佑樹, 野田明子, 尾崎紀夫

    日本睡眠学会第44回定期学術集会 

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    Event date： 2019.6

    Language：Japanese   Presentation type：Poster presentation  

  22. The effect of short sleep on lipid metabolism in Japanese university students. International conference

    Miyata S, Noda A, Iwamoto K, Fujishiro H, Taguchi R, Ozaki N

    24th Congress of the European Sleep Research Society 

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    Event date： 2018.9

    Language：English   Presentation type：Poster presentation  

    Country：Switzerland  

  23. 高齢睡眠呼吸障害患者における認知機能と嗅覚機能の検討

    宮田聖子、大竹宏直、野田明子

    第8回日本認知症予防学会学術集会 

    　More details

    Event date： 2018.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  24. Brain activity and life style in older people International conference

    Miyata S, Mita Y, Okuda M, Iwamoto K, Miyazaki S, Ozaki N, Noda A

    The 9th Congress of Asian Sleep Research Society 

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    Event date： 2018.7

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  25. Beneficial effects of positional therapy on cognitive function in elderly patients with obstructive sleep apnea International conference

    Noda A, Miyata S, Iwamoto K, Ozaki N

    Beneficial effects of positional therapy on cognitive function in elderly patients with obstructive sleep apnea 

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    Event date： 2018.6

    Language：English   Presentation type：Poster presentation  

    Country：United States  

  26. Polysomnographic and morphological characteristics in elderly patients with obstructive sleep apnea. International conference

    1. Miyata S, Otake H, Noda A, Okuda M, Ando M, Fujishiro H, Iwamoto K, Ozaki N

    World Sleep 2017 

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    Event date： 2017.10

    Language：English   Presentation type：Poster presentation  

    Country：Czech Republic  

  27. 閉塞性睡眠時無呼吸症候群における耳鼻咽喉科所見とCPAP使用状況の検討 Invited

    宮田聖子, 野田明子, 大竹宏直

    第9回中部睡眠循環呼吸研究会 

    　More details

    Event date： 2016.11

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  28. 地域在住高齢者における睡眠・睡眠呼吸障害の認知機能への影響

    宮田聖子, 野田明子, 安藤元郎, 松岡弘樹, 岩本邦弘, 藤城弘樹, 奥田将人, 大竹宏直, 宮﨑総一郎, 尾崎紀夫

    第6回日本認知症予防学会学術集会 

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    Event date： 2016.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  29. 高齢閉塞性睡眠時無呼吸症患者における睡眠ポリグラフ検査所見とCPAP治療継続への影響の検討

    宮田聖子, 大竹宏直, 藤城弘樹, 奥田将人, 岩本邦弘, 安田宜成, 野田明子, 尾崎紀夫

    日本睡眠学会第41回定期学術集会 

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    Event date： 2016.7

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  30. Differences in sleep duration and quality between weekdays and weekends in Japanese adults

    Miyata S, Iwamoto K, Ando M, Ito Y, Noda A, Ozaki N

    SLEEP2019 

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    Event date： 2016.6 - 2019.6

    Language：English   Presentation type：Poster presentation  

  31. Influences of patient characters and polysomnographic parameters on a sheet type home screening test. International conference

    Miyata S, Otake H, Fujishiro H, Okuda M, Noda A, Ozaki N

    SLEEP 

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    Event date： 2016.6

    Language：English   Presentation type：Poster presentation  

    Country：United States  

  32. 食塩感受性Dahlラットにおける水素ガスの高血圧への影響

    宮田聖子, 加藤和子, 野田明子

    第38回日本高血圧学会総会 

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    Event date： 2015.10

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  33. 睡眠不足と認知機能低下・気分障害との関係

    宮田聖子, 野田明子

    第5回日本認知症予防学会学術集会 

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    Event date： 2015.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  34. 閉塞性睡眠時無呼吸症候群における高齢期患者の病態生理に関する検討 Invited

    宮田聖子, 野田明子, 奥田将人, 大竹宏直

    第7回中部睡眠循環呼吸研究会 

    　More details

    Event date： 2014.9

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  35. 短時間睡眠による昼間の生活および精神機能への影響の検討 Invited

    宮田聖子, 野田明子, 尾崎紀夫

    日本睡眠学会第39回定期学術集会 

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    Event date： 2014.7

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  36. オーダーメイド寝具による睡眠への影響.

    宮田聖子, 野田明子

    日本睡眠学会第38回定期学術集会 

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    Event date： 2013.6

    Language：Japanese   Presentation type：Poster presentation  

    Venue：秋田   Country：Japan  

  37. Relation between excessive daytime sleepiness and cortical oxygenation during cognitive function task. International conference

    Miyata S, Noda A, Iwamoto K, Ozaki N.

    SLEEP 2013 Meeting 

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    Event date： 2013.6

    Language：English   Presentation type：Oral presentation (general)  

    Country：Japan  

  38. 睡眠と生活習慣 －寝具・運動・嗜好飲料との関係を中心に.

    宮田聖子, 野田明子

    日本睡眠学会第38回定期学術集会 

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    Event date： 2013.6

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

    Venue：秋田   Country：Japan  

  39. 緊急を要する心電図とアーチファクト.

    宮田聖子, 野田明子

    日本睡眠学会第38回定期学術集会 

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    Event date： 2013.6

    Language：Japanese   Presentation type：Symposium, workshop panel (nominated)  

    Venue：秋田   Country：Japan  

  40. 閉塞性睡眠時無呼吸症候群患者における負荷心エコー法による心機能評価.

    宮田聖子, 野田明子, 安田宜成, 大竹宏直, 平敷安希博, 室原豊明.

    第24回日本心エコー図学会学術集会. 

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    Event date： 2013.4

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  41. Endothelial function is impaired in obstructive sleep apnea syndrome.

    　More details

    Event date： 2013.3

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  42. 閉塞性睡眠時無呼吸症候群の運動時心肺機能応答.

    21. 宮田聖子、野田明子、平敷安希博、奥田将人、大竹宏直、安田宜成、室原豊明、中島務

    第50回睡眠呼吸障害研究会 

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    Event date： 2013.2

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  43. 近赤外線スペクトロスコピーによる短時間睡眠における脳血流量評価

    宮田聖子, 野田明子, 水野華子, 岩本邦弘, 尾崎紀夫

    第７回日本臨床検査学教育学会学術大会 

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    Event date： 2012.8

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  44. Chronic sleep restriction impaired brain tissue oxygenation in frontal lobe. International conference

    Miyata S, Noda A, Iwamoto K, Ozaki N

    SLEEP 2012 Meeting 

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    Event date： 2012.6

    Language：English   Presentation type：Oral presentation (general)  

    Country：United States  

  45. 加速度センサー内蔵歩数計による睡眠・覚醒リズム評価の検討.

    宮田聖子, 野田明子, 本多久美子, 岩本邦弘, 尾崎紀夫

    日本睡眠学会第37回定期学術集会 

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    Event date： 2012.6

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  46. Chronic sleep restriction inhibits brain activity measured by near-infrared spectroscopy. International conference

    Miyata S, Noda A, Ito M, Iwamoto K, Ozaki N

    20th European Congress of Psychiatry 

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    Event date： 2012.3

    Language：English   Presentation type：Oral presentation (general)  

    Country：Czech Republic  

  47. 高齢者における睡眠・睡眠呼吸障害と認知機能との関連

    宮田聖子, 野田明子, 奥田将人, 岩本邦弘, 尾崎紀夫

    第48回睡眠呼吸障害研究会 

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    Event date： 2012.2

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  48. 睡眠と２４時間血圧との関連の検討

    宮田聖子, 野田明子

    第18回日本時間生物学会学術集会 

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    Event date： 2011.11

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  49. Impact of masked hypertension/morning BP surge in obstructive sleep apnea syndrome. International conference

    Miyata S, Noda A, Yasuda Y, Okuda M, Otake H, Ozaki N, Nakashima T

    World Sleep 2011 

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    Event date： 2011.10

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

  50. 閉塞性睡眠時無呼吸症候群患者における仮面高血圧

    宮田聖子, 野田明子

    第50回中部医学検査学会 

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    Event date： 2011.10

    Language：Japanese   Presentation type：Oral presentation (general)  

    Country：Japan  

  51. Strain imaging法によるドブタミン負荷時の心筋虚血・収縮予備能評価

    宮田聖子, 野田明子, 平敷安希博, 大島覚, 奥村貴裕, 室原豊明

    第22回日本心エコー図学会学術集会 

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    Event date： 2011.4

    Language：Japanese   Presentation type：Poster presentation  

    Country：Japan  

  52. One night sleep restriction impairs the cortical oxygenation responses. International conference

    Miyata S, Noda A, Ito M, Iwamoto K, Ozaki N

    　More details

    Event date： 2011.3

    Language：English   Presentation type：Poster presentation  

    Country：Japan  

▼display all

To the head of Presentations.▲

Research Project for Joint Research, Competitive Funding, etc. 4

  1. 活動-休息リズムと休養感・精神症状との関連の検討

    2023.12 - 2024.11

    愛知健康増進財団  愛知健康増進財団　医学研究・健康増進活動 

    　 More details

    Authorship：Principal investigator  Grant type：Competitive

  2. 高齢期における閉塞性睡眠時無呼吸症の病態生理および治療効果への影響の検討

    2016.9 - 2017.8

    小林孫兵衛記念医学振興財団 

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    Grant type：Competitive

  3. 睡眠障害関連の心血管イベ ント予防を目的とする機器の開発

    2014 - 2015

    研究成果最適展開支援プログラム 

    　 More details

    Grant type：Competitive

  4. 短時間睡眠による昼間の生活および精神機能への影響の検討

    2013.7 - 2014.6

    臨床睡眠若手研究者助成 

    　 More details

    Grant type：Competitive

To the head of Research Project for Joint Research, Competitive Funding, etc..▲

KAKENHI (Grants-in-Aid for Scientific Research) 6

  1. Development of a simple method for behaviors during sleep

    Grant number：23K10934  2023.4 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    　 More details

    Authorship：Principal investigator 

    Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）

  2. Development of assessment method for lymphatic system in the brain: Evaluation of the influence by sleep.

    Grant number：21K07563  2021.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship：Coinvestigator(s) 

  3. 脂質網羅的解析による睡眠障害のメタボロミクスへの影響の検討

    Grant number：20K11577  2020.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    宮田 聖子, 野田 明子

    　 More details

    Authorship：Principal investigator 

    Grant amount：\4030000 （ Direct Cost: \3100000 、 Indirect Cost：\930000 ）

    睡眠分野においては質量分析法によるメタボロミクスは始まったばかりであり、睡眠障害による代謝性疾患の発症に関する分子的なメカニズムの解明が期待されている。脂質分子種グループはコレステロールや中性脂肪といった臨床の指標より鋭敏に変動しており、脂質メタボローム解析を用い、睡眠障害患者と大学生を対象に睡眠習慣、睡眠時間との脂質メタボロームとの関連を検討することにより、睡眠の障害が脂質代謝異常に与える影響についてそのメカニズムを包括的に検討する。
    睡眠は、代謝調節に重要な役割を果たし、睡眠障害は脂質代謝異常を来す。近年、質量分析計を用い睡眠障害による脂質代謝異常の分子的なメカニズムを解明しようという試みがなされている。閉塞性睡眠時無呼吸患者において重症度と脂質分子種プロファイルが関連すること、睡眠時間制限によりいくつかの脂質分子種が変動することが報告されている。質量分析計を用いた脂質代謝産物の包括的解析は、睡眠/覚醒調節および関連する代謝プロセスの理解をさらに深め、代謝プロファイリングを利用することで病態および治療効果評価においてバイオマーカー探索に不可欠となると考えられている。本研究では、睡眠覚醒リズムの障害や睡眠の障害のある者を対象に、質量分析法を用いた脂質メタボロミクス解析を実施し、睡眠と網羅的な脂質データとの関連を明らかにすることを目指している。我々のグループでは、若年者を対象に睡眠と血漿脂質分子種との関連を探索してきた。その結果、いくつかの脂質分子種と睡眠と関連が明らかとなってきた。2023年度は、この関係についてさらなる検証をする予定である。当初の計画では、睡眠障害の疑われる者を対象に、睡眠ポリグラフ検査または簡易睡眠検査を実施し、客観的/自覚的な睡眠評価を行い、末梢血の血漿検体をもちいて、質量分析法による網羅的脂質解析を実施する予定であった。しかし、2022年度もCOVID-19の影響により、臨床上の制限があり計画通りの検体採取と測定に困難があった。
    COVID-19による臨床上の制限により検体採取や測定が計画通りに進まなかった。
    本年度は、昨年度実施できなかった検体の収集を推進する。また、質量分析法については、情報収集を行い、測定を円滑に進められるよう測定法の進め方について計画の改善を図っていく。

  4. Study of mechanism of abnormal lipid metabolism in sleep-disordered breathing using mass spectrometry

    Grant number：16K16600  2016.4 - 2020.3

    Miyata Seiko

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    Authorship：Principal investigator 

    Grant amount：\3900000 （ Direct Cost: \3000000 、 Indirect Cost：\900000 ）

    The recent development of mass-spectrometry-based methods to resolve complex lipid components is having a profound effect on current approaches to analyzing the pathophysiological role of lipid species. In this study, we investigated the effect of sleep disordered-breathing (SDB) on lipid metabolism. Twelve patients with SDB and 15 healthy controls enrolled in this study. Lipid from plasma was evaluated using liquid extraction surface analysis with nanoelectrospray ionization mass spectrometry (LESA-MS). LESA-MS detected more than 1,400 lipid molecule species from seven lipid classes, including phosphatidylcholines (PC), phosphatidylethanolamines (PE), phosphatidylserine (PS), triacylglyceride (TAG), and sphingomyelins (SM). We identified 96 significantly different lipid species between patients with SDB and healthy controls. The association of SDB with molecular lipid species might reflect the importance of changes in lipid homeostasis in the pathogenesis of SDB.

  5. Development of an exercise and sleep habit program for improvement of cognitive function and prevention of depression

    Grant number：25282210  2013.4 - 2018.3

    NODA Akiko

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    Authorship：Coinvestigator(s) 

    Sleep disorder and insufficient sleep are frequently co-morbid with psychiatric disorders such as depression, which lead to cognitive performance declines. Although exercise and sleep duration habits are associated with cognitive function, their beneficial effects on cognitive function remain unclear. Hence, we developed an unrestricted sheet-shaped home monitoring including multipoint sensors, which could be a useful tool to monitor and manage sleep, resulting in prevention of sleep disorder, depression, and cognitive impairment. Moreover, we demonstrated that daily physical activity and sleep were differentially associated with cognitive function and brain activity using near-infrared spectroscopy. Our findings suggest that this new device is valuable and the exercise program that considers sleep cycle may have beneficial effects on extension of healthy life expectancy and reduction of health disparities.

  6. The analysis of lipid metabolism changes by short sleep duration and smoking

    Grant number：25870868  2013.4 - 2017.3

    MIYATA Seiko

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    Authorship：Principal investigator 

    Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）

    We studied the effect of short sleep duration and smoking on lipid metabolic changes and brain and endothelial function. Three nights of sleep restriction reduced the cortical oxygenation response during cognitive task compared to that in natural sleep. Endothelial function after smoking was significantly impaired than that at rest in young smokers. We identified significant changes of 168, 72 and 39 lipid species between natural sleep and sleep restriction, smokers and non-smokers, and pre- and post-smoking using electrospray ionization mass spectrometry.

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Industrial property rights 1

  1. 分類システム

    藤原幸一、尾崎紀夫、岩本邦弘、宮田聖子、角田柊二

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    Application no：特願2022-169896 

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Teaching Experience (On-campus) 2

  1. 現代医学入門

    2023

  2. 健康と文化

    2020

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Teaching Experience (Off-campus) 2

  1. 臨床検査総合実習、人体情報学

    2018.4 （Chubu University）

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    Level：Undergraduate (specialized) 

  2. 歯科診療補助論Ⅳ（臨床検査）

    2017.4

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Social Contribution 4

  1. 認知症対応力向上講習会B

    Role(s)：Lecturer,　Organizing member

    愛知県臨床検査技師会/日本臨床検査技師会  2019.2

  2. 認知症対応力向上講習会B

    Role(s)：Lecturer,　Organizing member

    愛知県臨床検査技師会/日本臨床検査技師会  2018.2

  3. 全国「検査と健康展」実務委員

    Role(s)：Organizing member,　Demonstrator

    愛知県臨床検査技師会/日本臨床検査技師会  2017.11

  4. 日本PSG研究会東海支部例会実習講師

    Role(s)：Lecturer,　Organizing member

    日本PSG研究会東海支部  2006.7

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