Updated on 2024/04/03

写真a

 
YAMAMURA Takeshi
 
Organization
Nagoya University Hospital Gastroenterology Lecturer of hospital
Title
Lecturer of hospital

Degree 1

  1. 医学博士 ( 2014.1   名古屋大学 ) 

Research Areas 1

  1. Others / Others  / 小腸・大腸

Education 1

  1. Nagoya University   Faculty of Medicine

    - 2002.3

      More details

    Country: Japan

Professional Memberships 5

  1. 日本消化器病学会   専門医・指導医・支部評議員・学会評議員

  2. 日本消化器内視鏡学会   専門医・指導医・支部評議員・学会評議員

  3. 日本内科学会   認定医・専門医・指導医

  4. 日本消化管学会   専門医,指導医

  5. 日本カプセル内視鏡学会   認定医・代議員

 

Papers 200

  1. Artificial intelligence-based diagnostic imaging system with virtual enteroscopy and virtual unfolded views to evaluate small bowel lesions in Crohn's disease.

    Furukawa K, Oda M, Watanabe O, Nakamura M, Yamamura T, Maeda K, Mori K, Kawashima H

    Revista espanola de enfermedades digestivas     2024.3

     More details

    Language:English  

    DOI: 10.17235/reed.2024.10405/2024

    PubMed

  2. Efficacy of endoscopic submucosal resection with a ligation device for small rectal neuroendocrine tumor: study protocol of a multicenter open-label randomized control trial (BANDIT trial)

    Takada, K; Imai, K; Yamada, T; Ohata, K; Kanesaka, T; Nagami, Y; Yamasaki, Y; Kobara, H; Inokuchi, Y; Chino, A; Yamaguchi, S; Ikehara, H; Kawamura, T; Yabuuchi, Y; Mizuguchi, Y; Ikematsu, H; Yokoi, C; Hattori, S; Ohno, K; Yoshizawa, Y; Fukuzawa, M; Tsuji, Y; Konishi, J; Yamamura, T; Osawa, S; Oka, S; Hikichi, T; Togashi, K; Hirasawa, K; Uraoka, T; Takeuchi, Y; Chiba, H; Komeda, Y; Doyama, H; Oba, MS; Saito, Y

    BMC GASTROENTEROLOGY   Vol. 24 ( 1 ) page: 69   2024.2

     More details

  3. Risk factors for rebleeding in gastroduodenal ulcers

    Ito, N; Funasaka, K; Fujiyoshi, T; Nishida, K; Satta, Y; Furukawa, K; Kakushima, N; Furune, S; Ishikawa, E; Mizutani, Y; Sawada, T; Maeda, K; Ishikawa, T; Yamamura, T; Ohno, E; Nakamura, M; Miyahara, R; Sasaki, Y; Haruta, JI; Fujishiro, M; Kawashima, H

    IRISH JOURNAL OF MEDICAL SCIENCE   Vol. 193 ( 1 ) page: 173 - 179   2024.2

     More details

  4. An Analysis of Delayed Bleeding in Cases of Colorectal Endoscopic Submucosal Dissection Due to Types of Direct Oral Anticoagulants in Japan

    Yoshida, N; Hayashi, Y; Togo, D; Oka, S; Takada, K; Fukunaga, S; Morita, Y; Hayashi, T; Kozuka, K; Tsuji, Y; Murakami, T; Yamamura, T; Komeda, Y; Takeuchi, Y; Shinmura, K; Fukuda, H; Yoshii, S; Ono, S; Katsuki, S; Kawashima, K; Nemoto, D; Yamamoto, H; Saito, Y; Tamai, N; Iwao, A; Itoi, Y; Tsuji, S; Inagaki, Y; Inada, Y; Soga, K; Hasegawa, D; Murakami, T; Yoriki, H; Fukumoto, K; Motoyoshi, T; Nakatani, Y; Sano, Y; Iguchi, M; Fujii, S; Ban, HRMT; Harada, K; Okamoto, K; Nishiyama, H; Sasaki, F; Mizukami, K; Shono, T; Shimoda, R; Miike, T; Yamaguchi, N

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY   Vol. 22 ( 2 ) page: 271 - 282.e3   2024.2

     More details

  5. Monoclonal Antibody Against Mature Interleukin-18 Ameliorates Colitis in Mice and Improves Epithelial Barrier Function

    Ikegami, S; Maeda, K; Urano, T; Mu, JX; Nakamura, M; Yamamura, T; Sawada, T; Ishikawa, E; Yamamoto, K; Muto, H; Oishi, A; Iida, T; Mizutani, Y; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Ishigami, M; Kawashima, H

    INFLAMMATORY BOWEL DISEASES     2023.12

     More details

  6. Association of direct oral anticoagulant and delayed bleeding with pharmacokinetics after endoscopic submucosal dissection.

    Murata M, Sugimoto M, Ueshima S, Nagami Y, Ominami M, Sawaya M, Nakatani Y, Furumoto Y, Dohi O, Sumiyoshi T, Fukuzawa M, Tsuji S, Miyahara K, Takeuchi Y, Suzuki S, Tominaga N, Yagi N, Osawa S, Sakata Y, Yamada T, Yoshizawa Y, Yamauchi A, Yamamura T, Orihara S, Miyamoto S, Matsuda S, Hira D, Terada T, Katsura T, Gotoda T, Fujishiro M, Kawai T

    Gastrointestinal endoscopy     2023.12

     More details

    Language:English  

    DOI: 10.1016/j.gie.2023.11.048

    PubMed

  7. Current status of and future issues related to endoscopic papillectomy

    Kawashima, H; Ishikawa, T; Yamao, K; Mizutani, Y; Iida, T; Uetsuki, K; Yamamura, T; Furukawa, K; Nakamura, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 85 ( 4 ) page: 648 - 658   2023.11

     More details

  8. Real-World Effectiveness and Risk Factors for Discontinuation of Ustekinumab in Ulcerative Colitis.

    Uchida G, Nakamura M, Yamamura T, Maeda K, Sawada T, Ishikawa E, Furukawa K, Iida T, Mizutani Y, Yamao K, Ishikawa T, Ishizu Y, Honda T, Ishigami M, Kawashima H

    Inflammatory intestinal diseases   Vol. 8 ( 2 ) page: 60 - 68   2023.10

     More details

    Language:English  

    DOI: 10.1159/000531497

    PubMed

  9. Multicenter prospective registration study of efficacy and safety of capsule endoscopy in Crohn's disease in Japan (SPREAD-J study)

    Sakurai, T; Omori, T; Tanaka, H; Ito, T; Ando, K; Yamamura, T; Nanjjo, S; Osawa, S; Takeda, T; Watanabe, K; Hiraga, H; Yamamoto, S; Ozeki, K; Tanaka, S; Tajiri, H; Saruta, M; SPREAD J Grp

    JOURNAL OF GASTROENTEROLOGY   Vol. 58 ( 10 ) page: 1003 - 1014   2023.10

     More details

  10. Randomized trial comparing 15 <i>vs</i> 5 actuations per pass during endoscopic ultrasound-guided fine-needle biopsy for specimen acquisition of solid pancreatic lesions

    Kataoka, K; Ishikawa, T; Ohno, E; Yamao, K; Mizutani, Y; Iida, T; Kato, K; Kinoshita, F; Yamamura, T; Furukawa, K; Nakamura, M; Kawashima, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 38 ( 9 ) page: 1647 - 1655   2023.9

     More details

  11. Clinical characteristics of Dieulafoy's lesion in the small bowel diagnosed and treated by double-balloon endoscopy

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Furukawa, K; Iida, T; Mizutani, Y; Yamao, K; Ishikawa, T; Honda, T; Ishigami, M; Kawashima, H

    BMC GASTROENTEROLOGY   Vol. 23 ( 1 ) page: 290   2023.8

     More details

  12. Real-world effectiveness of ustekinumab for patients with ulcerative colitis: a systematic review and meta-analysis

    Uchida, G; Nakamura, M; Yamamura, T; Tsuzuki, T; Kawashima, H

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 85 ( 3 ) page: 402 - 427   2023.8

     More details

  13. Systematic Review and Meta-Analysis of the Use of Serum Leucine-Rich Alpha-2 Glycoprotein to Assess Crohn's Disease Activity

    Okita, M; Nakashima, K; Yamamura, T; Matsui, S

    INFLAMMATORY BOWEL DISEASES     2023.7

     More details

  14. Efficacy of 1-kestose supplementation in patients with mild to moderate ulcerative colitis: A randomised, double-blind, placebo-controlled pilot study International journal

    Ikegami, S; Nakamura, M; Honda, T; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Yamamoto, K; Furune, S; Ishikawa, T; Furukawa, K; Ohno, E; Ishigami, M; Kinoshita, F; Kadota, Y; Tochio, T; Shimomura, Y; Hirooka, Y; Kawashima, H

    ALIMENTARY PHARMACOLOGY & THERAPEUTICS   Vol. 57 ( 11 ) page: 1249 - 1257   2023.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/apt.17387

    Web of Science

    PubMed

  15. Management of colorectal high-grade dysplasia or cancer resected by cold snare polypectomy: a multicenter exploratory study

    Inoki, K; Takamaru, H; Furuhashi, H; Kishida, Y; Shimodate, Y; Sumida, Y; Hosotani, K; Ueyama, H; Furumoto, Y; Hashimoto, S; Takeuchi, Y; Ichijima, R; Yoshizawa, Y; Suzuki, T; Minoda, Y; Mizukami, K; Matsumura, T; Kasai, T; Yamamura, T; Ohnita, K; Hara, K; Esaki, M; Katagiri, A; Ishikawa, H; Gotoda, T

    JOURNAL OF GASTROENTEROLOGY   Vol. 58 ( 6 ) page: 554 - 564   2023.6

     More details

  16. Linked-Color Imaging Detects More Colorectal Adenoma and Serrated Lesions: An International Randomized Controlled Trial

    Suzuki, S; Aniwan, S; Chiu, HM; Laohavichitra, K; Chirapongsathorn, S; Yamamura, T; Kuo, CY; Yoshida, N; Ang, TL; Takezawa, T; Rerknimitr, R; Ishikawa, H; Gotoda, T

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY   Vol. 21 ( 6 ) page: 1493 - +   2023.6

     More details

  17. ENDOSCOPIC TREATMENT OF DUODENAL NEUROENDOCRINE TUMORS

    Furukawa, K; Furune, S; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Nakamura, M; Kawashima, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 97 ( 6 ) page: AB1211 - AB1212   2023.6

     More details

  18. COMPARISON OF COLON ADENOMA DETECTION RATE USING TRANSPARENT CAP-ASSISTED AND CONVENTIONAL COLONOSCOPY: RESULT FROM A CONSORTIUM OF INTERNATIONAL TERTIARY-CARE ENDOSCOPY CENTERS IN ASIA

    Chirapongsathorn, S; Prasanwon, P; Suzuki, S; Aniwan, S; Chen, YN; Chantarojanasiri, T; Yamamura, T; Kuo, CY; Yoshida, N; Ang, TL; Takezawa, T; Ishikawa, H; Gotoda, T

    GASTROINTESTINAL ENDOSCOPY   Vol. 97 ( 6 ) page: AB237 - AB237   2023.6

     More details

  19. Diagnostic Performance of Endocytoscopy for Esophageal Eosinophilia

    Hida, E; Muroi, K; Kakushima, N; Furune, S; Ishikawa, E; Mizutani, Y; Sawada, T; Keiko, M; Yamamura, T; Ishikawa, T; Furukawa, K; Ohno, E; Nakamura, M; Nishida, K; Fujishiro, M; Kawashima, H

    DIGESTION   Vol. 104 ( 3 ) page: 202 - 211   2023.6

     More details

  20. COMPARISON OF COLON ADENOMA DETECTION RATE USING TRANSPARENT CAP-ASSISTED AND CONVENTIONAL COLONOSCOPY: RESULT FROM A CONSORTIUM OF INTERNATIONAL TERTIARY-CARE ENDOSCOPY CENTERS IN ASIA

    Chirapongsathorn, S; Prasanwon, P; Suzuki, S; Aniwan, S; Chen, YN; Chantarojanasiri, T; Yamamura, T; Kuo, CY; Yoshida, N; Ang, TL; Takezawa, T; Ishikawa, H; Gotoda, T

    GASTROINTESTINAL ENDOSCOPY   Vol. 97 ( 6 ) page: AB135 - AB135   2023.6

     More details

  21. CO<sub>2</sub> enterography in endoscopic retrograde cholangiography using double-balloon endoscopy: A randomized clinical trial

    Murate, K; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Kida, Y; Esaki, M; Hamazaki, M; Iida, T; Mizutani, Y; Yamao, K; Ishikawa, T; Furukawa, K; Ohno, E; Honda, T; Ishigami, M; Kinoshita, F; Ando, M; Kawashima, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 38 ( 5 ) page: 761 - 767   2023.5

     More details

  22. Novel endoscopic approaches using the endocytoscopy for the target biopsy in esophageal eosinophilia

    Muroi, K; Kakushima, N; Furukawa, K; Furune, S; Ito, N; Hirose, T; Hida, E; Suzuki, T; Suzuki, T; Hirai, K; Shibata, H; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ohno, E; Nakamura, M; Fujishiro, M; Kawashima, H

    ESOPHAGUS   Vol. 20 ( 2 ) page: 325 - 332   2023.4

     More details

  23. Accuracy of Serum Leucine-Rich Alpha-2 Glycoprotein in Evaluating Endoscopic Disease Activity in Crohn's Disease Reviewed International journal

    Kawamura, T; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Ishikawa, E; Iida, T; Mizutani, Y; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M

    INFLAMMATORY BOWEL DISEASES   Vol. 29 ( 2 ) page: 245 - 253   2023.2

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ibd/izac076

    Web of Science

    PubMed

  24. Factors Related to Delayed Adverse Events of Endoscopic Submucosal Dissection in the Duodenum

    Kawamura, T; Hirose, T; Kakushima, N; Furukawa, K; Furune, S; Ishikawa, E; Sawada, T; Keiko, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Honda, T; Ishigami, M; Kawashima, H; Fujishiro, M

    DIGESTIVE DISEASES   Vol. 41 ( 1 ) page: 80 - 88   2023.1

     More details

  25. Current status of transanal total mesorectal excision for rectal cancer and the expanding indications of the transanal approach for extended pelvic surgeries

    Uehara, K; Ogura, A; Murata, Y; Sando, M; Mukai, T; Aiba, T; Yamamura, T; Nakamura, M

    DIGESTIVE ENDOSCOPY   Vol. 35 ( 2 ) page: 243 - 254   2023.1

     More details

  26. Network Analysis of Gut Microbiota Including <i>Fusobacterium</i> and Oral Origin Bacteria and Their Distribution on Tumor Surface, Normal Mucosa, and in Feces in Patients with Colorectal Cancer

    Ohashi, A; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Ishikawa, E; Yamamoto, K; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    DIGESTION   Vol. 103 ( 6 ) page: 451 - 461   2022.12

     More details

  27. The effects of ustekinumab on small intestinal lesions and stenotic lesions

    Wada, H; Murate, K; Nakamura, M; Furukawa, K; Kakushima, N; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Ishikawa, T; Ohno, E; Honda, T; Kawashima, H; Nakayama, G; Hattori, N; Umeda, S; Ishigami, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 4 ) page: 825 - 838   2022.11

     More details

  28. Analysis of immunologic comorbidities in ulcerative colitis patients: a tool to prevent exacerbations in ulcerative colitis cases

    Meza, MRR; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Kakushima, N; Furukawa, K; Iida, T; Mizutani, Y; Ishikawa, T; Ohno, E; Honda, T; Kawashima, H; Ishigami, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 4 ) page: 733 - 745   2022.11

     More details

  29. The role of EUS elastography-guided fine needle biopsy in the histological diagnosis of solid pancreatic lesions: a prospective exploratory study

    Ohno, E; Kawashima, H; Ishikawa, T; Mizutani, Y; Iida, T; Nishio, R; Uetsuki, K; Yashika, J; Yamada, K; Yoshikawa, M; Gibo, N; Aoki, T; Kataoka, K; Mori, H; Takada, Y; Aoi, H; Takahashi, H; Yamamura, T; Furukawa, K; Nakamura, M; Shimoyama, Y; Hirooka, Y; Fujishiro, M

    SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page: 16603   2022.10

     More details

  30. Modified N score is helpful for identifying patients who need endoscopic intervention among those with black stools without hematemesis

    Ito, N; Funasaka, K; Fujiyoshi, T; Furukawa, K; Kakushima, N; Furune, S; Ishikawa, E; Mizutani, Y; Sawada, T; Maeda, K; Ishikawa, T; Yamamura, T; Ohno, E; Nakamura, M; Kawashima, H; Miyahara, R; Hirooka, Y; Haruta, JI; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 34 ( 6 ) page: 1157 - 1165   2022.9

     More details

  31. Examination of Abnormal Alpha-synuclein Aggregates in the Enteric Neural Plexus in Patients with Ulcerative Colitis

    Gibo, N; Hamaguchi, T; Miki, Y; Yamamura, T; Nakaguro, M; Ito, M; Nakamura, M; Kawashima, H; Hirayama, M; Hirooka, Y; Wakabayashi, K; Ohno, K

    JOURNAL OF GASTROINTESTINAL AND LIVER DISEASES   Vol. 31 ( 3 ) page: 290 - 300   2022.9

     More details

  32. Endoscopic management of perihilar cholangiocarcinoma

    Kawashima, H; Ohno, E; Ishikawa, T; Mizutani, Y; Iida, T; Yamamura, T; Kakushima, N; Furukawa, K; Nakamura, M

    DIGESTIVE ENDOSCOPY   Vol. 34 ( 6 ) page: 1147 - 1156   2022.9

     More details

  33. Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan

    Hamazaki, M; Sawada, T; Yamamura, T; Maeda, K; Mizutani, Y; Ishikawa, E; Furune, S; Yamamoto, K; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Nakamura, M; Fujishiro, M

    BMC GASTROENTEROLOGY   Vol. 22 ( 1 ) page: 342   2022.7

     More details

  34. Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma

    Aoki, T; Ohno, E; Ishikawa, T; Mizutani, Y; Iida, T; Yamao, K; Yamamura, T; Furukawa, K; Nakamura, M; Honda, T; Ishigami, M; Yatsuya, H; Kawashima, H

    BMC GASTROENTEROLOGY   Vol. 22 ( 1 ) page: 329   2022.7

     More details

  35. Effects of steroid use for stenosis prevention after endoscopic submucosal dissection for cervical esophageal cancer

    Muroi, K; Kakushima, N; Furukawa, K; Furune, S; Ito, N; Hirose, T; Ishikawa, E; Mizutani, Y; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Funasaka, K; Miyahara, R; Fujishiro, M

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 27 ( 5 ) page: 940 - 947   2022.5

     More details

  36. Relationship between psoas muscle index and long-term survival in older patients aged ≥ 80 years after endoscopic submucosal dissection for gastric cancer

    Ito, N; Funasaka, K; Miyahara, R; Furukawa, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Hirooka, Y; Fujishiro, M

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 27 ( 4 ) page: 729 - 738   2022.4

     More details

  37. Gelsolin as a Potential Biomarker for Endoscopic Activity and Mucosal Healing in Ulcerative Colitis

    Maeda, K; Nakamura, M; Yamamura, T; Sawada, T; Ishikawa, E; Oishi, A; Ikegami, S; Kakushima, N; Furukawa, K; Iida, T; Mizutani, Y; Ishikawa, T; Ohno, E; Honda, T; Ishigami, M; Kawashima, H

    BIOMEDICINES   Vol. 10 ( 4 )   2022.4

     More details

  38. Diagnostic performance of endoscopic classifications for neoplastic lesions in patients with ulcerative colitis: A retrospective case-control study

    Kida, Y; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Mizutani, Y; Kakushima, N; Furukawa, K; Ishikawa, T; Ohno, E; Kawashima, H; Nakamura, M; Ishigami, M; Fujishiro, M

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 28 ( 10 ) page: 1055 - 1066   2022.3

     More details

  39. The impact of the age-adjusted Charlson comorbidity index as a prognostic factor for endoscopic papillectomy in ampullary tumors

    Takada, Y; Kawashima, H; Ohno, E; Ishikawa, T; Mizutani, Y; Iida, T; Yamamura, T; Kakushima, N; Furukawa, K; Nakamura, M; Honda, T; Ishigami, M; Ito, A; Hirooka, Y

    JOURNAL OF GASTROENTEROLOGY   Vol. 57 ( 3 ) page: 199 - 207   2022.3

     More details

  40. Fecal incontinence and oral regurgitation during duodenal endoscopic submucosal dissection using the water pressure method

    Takada, Y; Hirose, T; Nishida, K; Kakushima, N; Furukawa, K; Furune, S; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Honda, T; Ishigami, M; Kawashima, H; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 34 ( 3 ) page: 526 - 534   2022.3

     More details

  41. Artificial intelligence-based diagnosis of upper gastrointestinal subepithelial lesions on endoscopic ultrasonography images

    Hirai, K; Kuwahara, T; Furukawa, K; Kakushima, N; Furune, S; Yamamoto, H; Marukawa, T; Asai, H; Matsui, K; Sasaki, Y; Sakai, D; Yamada, K; Nishikawa, T; Hayashi, D; Obayashi, T; Komiyama, T; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Ishigami, M; Fujishiro, M

    GASTRIC CANCER   Vol. 25 ( 2 ) page: 382 - 391   2022.3

     More details

  42. A novel scoring system to predict therapeutic intervention for non-variceal upper gastrointestinal bleeding

    Ito, N; Funasaka, K; Furukawa, K; Kakushima, N; Hirose, T; Muroi, K; Suzuki, T; Suzuki, T; Hida, E; Ishikawa, T; Yamamura, T; Ohno, E; Nakamura, M; Kawashima, H; Miyahara, R; Fujishiro, M

    INTERNAL AND EMERGENCY MEDICINE   Vol. 17 ( 2 ) page: 423 - 430   2022.3

     More details

  43. Initial experience of tofacitinib for treating refractory moderate-to-severe ulcerative colitis

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, H; Honda, T; Ishigami, M; Fujishiro, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 1 ) page: 169 - 179   2022.2

     More details

  44. Gastrointestinal: Idiopathic omental hemorrhage

    Furukawa, K; Yamamura, T; Nakamura, M; Kawashima, H; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 37 ( 2 ) page: 282 - 282   2022.2

     More details

  45. Usefulness of Macroscopic On-Site Evaluation Using a Stereomicroscope during EUS-FNB for Diagnosing Solid Pancreatic Lesions

    Ishikawa, T; Ohno, E; Mizutani, Y; Iida, T; Uetsuki, K; Yashika, J; Yamada, K; Gibo, N; Aoki, T; Kataoka, K; Mori, H; Takada, Y; Takahashi, H; Aoi, H; Kato, K; Yamamura, T; Kakushima, N; Furukawa, K; Nakamura, M; Hirooka, Y; Kawashima, H

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 2022   page: 2737578   2022.1

     More details

  46. Evaluation of ulcerative colitis activity using transabdominal ultrasound shear wave elastography

    Yamada, K; Ishikawa, T; Kawashima, H; Ohno, E; Iida, T; Ishikawa, E; Mizutani, Y; Sawada, T; Maeda, K; Yamamura, T; Kakushima, N; Furukawa, K; Nakamura, M; Ishigami, M; Fujishiro, M

    QUANTITATIVE IMAGING IN MEDICINE AND SURGERY   Vol. 12 ( 1 ) page: 618 - 626   2022.1

     More details

  47. Preliminary Comparison of Endoscopic Brush and Net Catheters as the Sampling Tool to Analyze the Intestinal Mucus in the Rectum with Ulcerative Colitis Patients

    Nakamura, M; Maeda, K; Yamamoto, K; Yamamura, T; Sawada, T; Ishikawa, E; Kakushima, N; Furukawa, K; Iida, T; Mizutani, Y; Ishikawa, T; Ohno, E; Honda, T; Ishigami, M; Kawashima, H

    DIGESTION   Vol. 103 ( 3 ) page: 232 - 243   2022

     More details

  48. Immunoproliferative Small Intestinal Disease Diagnosed by Double-balloon Endoscopy with Biopsy Sampling

    Meza, MRR; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M

    INTERNAL MEDICINE   Vol. 61 ( 17 ) page: 2593 - 2599   2022

     More details

  49. Comparison of Endoscopic Ultrasonography and Conventional Endoscopy for Prediction of Tumor Depth in Superficial Nonampullary Duodenal Epithelial Tumors

    Matsuda, N; Hirose, T; Kakushima, N; Furukawa, K; Furune, S; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Honda, T; Ishigami, M; Kawashima, H; Fujishiro, M

    DIGESTION   Vol. 103 ( 4 ) page: 319 - 328   2022

     More details

  50. Real-world local recurrence rate after cold polypectomy in colorectal polyps less than 10 mm using propensity score matching

    Saito, M; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Ishikawa, E; Mizutani, Y; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, H; Ishigami, M; Fujishiro, M

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 27 ( 47 ) page: 8182 - 8193   2021.12

     More details

  51. Clinical characteristics of gastrointestinal immune-related adverse events of immune checkpoint inhibitors and their association with survival

    Yamada, K; Sawada, T; Nakamura, M; Yamamura, T; Maeda, K; Ishikawa, E; Iida, T; Mizutani, Y; Kakushima, N; Ishikawa, T; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Furune, S; Hase, T; Yokota, K; Maeda, O; Hashimoto, N; Akiyama, M; Ando, Y; Fujishiro, M

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 27 ( 41 ) page: 7190 - 7206   2021.11

     More details

  52. Endocytoscopy Is Useful for the Diagnosis of Superficial Nonampullary Duodenal Epithelial Tumors

    Hirose, T; Kakushima, N; Furukawa, K; Furune, S; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Nishida, K; Yokoi, T; Kawashima, H; Fujishiro, M

    DIGESTION   Vol. 102 ( 6 ) page: 895 - 902   2021.11

     More details

  53. Usefulness of functional splicing analysis to confirm precise disease pathogenesis in Diamond-Blackfan anemia caused by intronic variants in RPS19

    Takafuji Satoru, Mori Takeshi, Nishimura Noriyuki, Yamamoto Nobuyuki, Uemura Suguru, Nozu Kandai, Terui Kiminori, Toki Tsutomu, Ito Etsuro, Muramatsu Hideki, Takahashi Yoshiyuki, Matsuo Masafumi, Yamamura Tomohiko, Iijima Kazumoto

    PEDIATRIC HEMATOLOGY AND ONCOLOGY   Vol. 38 ( 6 ) page: 515 - 527   2021.9

     More details

  54. The role of early video capsule endoscopy in the diagnosis and prognosis of obscure gastrointestinal bleeding: A multi-center propensity score matching study

    Zhao, R; Nakamura, M; Wu, S; Uchida, G; Yamamura, T; Gao, YJ; Goto, H; Fujishiro, M; Ge, ZZ

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36 ( 9 ) page: 2540 - 2548   2021.9

     More details

  55. Endoscopic Ultrasound Elastography as a Novel Diagnostic Method for the Assessment of Hardness and Depth of Invasion in Colorectal Neoplasms

    Esaki, M; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Suzuki, H; Kuno, T; Yamada, K; Hasegawa, I; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, H; Hirooka, Y; Fujishiro, M

    DIGESTION   Vol. 102 ( 5 ) page: 701 - 713   2021.9

     More details

  56. Feasibility of patency capsule and colon capsule endoscopy in patients with suspected gastrointestinal stenosis: a prospective study

    Otsuka, H; Nakamura, M; Yamamura, T; Maeda, K; Sawade, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, I; Honda, T; Ishigami, M; Fujishiro, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 3 ) page: 419 - 430   2021.8

     More details

  57. Detection of Colorectal Neoplasms Using Linked Color Imaging: A Prospective, Randomized, Tandem Colonoscon Trial

    Hasegawa, I; Yamamura, T; Suzuki, H; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, H; Nakamura, M; Fujishiro, M

    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY   Vol. 19 ( 8 ) page: 1708 - +   2021.8

     More details

  58. Difference of efficacy for small bowel lesion in Crohn

    Sawada T., Nakamura M., Yamamura T., Maeda K., Ishikawa E., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36   page: 116 - 116   2021.8

     More details

  59. Difference of efficacy for small bowel lesion in Crohn

    Sawada, T; Nakamura, M; Yamamura, T; Maeda, K; Ishikawa, E; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36   page: 116 - 116   2021.8

     More details

  60. A forward-viewing radial-array echoendoscope is useful for diagnosing the depth of colorectal neoplasia invasion

    Kuno, T; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Mizutani, Y; Esaki, M; Ishikawa, T; Furukawa, K; Ohno, E; Kawashima, H; Fujishiro, M

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 35 ( 8 ) page: 4389 - 4398   2021.8

     More details

  61. Subjective Symptoms in Patients with Eosinophilic Esophagitis Are Related to Esophageal Wall Thickness and Esophageal Body Pressure

    Muroi, K; Kakushima, N; Furukawa, K; Ishikawa, E; Sawada, T; Ishikawa, T; Maeda, K; Yamamura, T; Ohno, E; Nakamura, M; Kawashima, H; Funasaka, K; Miyahara, R; Fujishiro, M

    DIGESTIVE DISEASES AND SCIENCES   Vol. 66 ( 7 ) page: 2291 - 2300   2021.7

     More details

  62. Lewis score on capsule endoscopy can predict the prognosis in patients with small bowel lesions of Crohn's disease

    Nishikawa, T; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 36 ( 7 ) page: 1851 - 1858   2021.7

     More details

  63. Long-Term Prognostic Predictors of Esophageal Squamous Cell Carcinoma Potentially Indicated for Endoscopic Submucosal Dissection

    Suzuki, T; Furukawa, K; Funasaka, K; Ishikawa, E; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Miyahara, R; Fujishiro, M

    DIGESTION   Vol. 102 ( 4 ) page: 563 - 571   2021.6

     More details

  64. Comparison of High-Resolution Manometry in Patients Complaining of Dysphagia among Patients with or without Diabetes Mellitus

    Muroi, K; Miyahara, R; Funasaka, K; Furukawa, K; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Onoue, T; Arima, H; Hirooka, Y; Fujishiro, M

    DIGESTION   Vol. 102 ( 4 ) page: 554 - 562   2021.6

     More details

  65. An evaluation of resectability among endoscopic treatment methods for rectal neuroendocrine tumors &lt;10 mm

    Toriyama, K; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Furukawa, K; Ishikawa, T; Ohno, E; Kawashima, H; Fujishiro, M

    ARAB JOURNAL OF GASTROENTEROLOGY   Vol. 22 ( 2 ) page: 104 - 110   2021.6

     More details

  66. New modality for the quantitative evaluation of tissue elasticity using a forward-viewing radial-array echoendoscope for colorectal neoplasms

    Esaki, M; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Furukawa, K; Kawashima, H; Hirooka, Y; Fujishiro, M

    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE   Vol. 36 ( 5 ) page: 919 - 927   2021.5

     More details

  67. Diagnostic performance of endoscopic ultrasonography-guided elastography for solid pancreatic lesions: Shear-wave measurements versus strain elastography with histogram analysis

    Ohno, E; Kawashima, H; Ishikawa, T; Iida, T; Suzuki, H; Uetsuki, K; Yashika, J; Yamada, K; Yoshikawa, M; Gibo, N; Aoki, T; Kataoka, K; Mori, H; Yamamura, T; Furukawa, K; Nakamura, M; Hirooka, Y; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 33 ( 4 ) page: 629 - 638   2021.5

     More details

  68. Clinical Features of Ischemic Enteritis Diagnosed by Double-Balloon Endoscopy

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Kakushima, N; Furukawa, K; Ishikawa, T; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 2021   page: 8875564   2021.4

     More details

  69. Filtrated Adipose Tissue-Derived Mesenchymal Stem Cell Lysate Ameliorates Experimental Acute Colitis in Mice

    Nishikawa, T; Maeda, K; Nakamura, M; Yamamura, T; Sawada, T; Mizutani, Y; Ito, T; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Honda, T; Ishigami, M; Yamamoto, T; Matsumoto, S; Hotta, Y; Fujishiro, M

    DIGESTIVE DISEASES AND SCIENCES   Vol. 66 ( 4 ) page: 1034 - 1044   2021.4

     More details

  70. Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract

    Yamada, K; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Kawashima, H; Honda, T; Ishigami, M; Fujishiro, M

    BMC GASTROENTEROLOGY   Vol. 21 ( 1 ) page: 75   2021.2

     More details

  71. Ustekinumab is effective against small bowel lesions in Crohn's disease: two case reports

    Murate, K; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 14 ( 1 ) page: 129 - 135   2021.2

     More details

  72. Clinical characteristics and long-term prognosis of autoimmune pancreatitis with renal lesions

    Ishikawa, T; Kawashima, H; Ohno, E; Iida, T; Suzuki, H; Uetsuki, K; Yashika, J; Yamada, K; Yoshikawa, M; Gibo, N; Aoki, T; Kataoka, K; Mori, H; Yamamura, T; Furukawa, K; Nakamura, M; Hirooka, Y; Fujishiro, M

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 406   2021.1

     More details

  73. Neurokinin 3 receptor-selective agonist, senktide, decreases core temperature in Japanese Black cattle

    Nakamura S., Miwa M., Morita Y., Ohkura S., Yamamura T., Wakabayashi Y., Matsuyama S.

    DOMESTIC ANIMAL ENDOCRINOLOGY   Vol. 74   2021.1

     More details

  74. Systematic review and meta-analysis of the diagnostic and therapeutic yield of small bowel endoscopy in patients with overt small bowel bleeding

    Uchida, G; Nakamura, M; Yamamura, T; Furukawa, K; Kawashima, H; Honda, T; Ishigami, M; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 33 ( 1 ) page: 66 - 82   2021.1

     More details

  75. Gastrointestinal tract metastasis of lung cancer: The PD-L1 expression and correlated clinicopathological variables

    Ishikawa, E; Nakaguro, M; Nakamura, M; Yamamura, T; Sawada, T; Mizutani, Y; Maeda, K; Furukawa, K; Shimoyama, Y; Kawashima, H; Fujishiro, M

    PATHOLOGY INTERNATIONAL   Vol. 71 ( 1 ) page: 33 - 41   2021.1

     More details

  76. A novel Lugol's iodine staining technique to visualize the upper margin of the surgical anal canal intraoperatively for Hirschsprung disease: a case series

    Yokota, K; Amano, H; Kudo, T; Yamamura, T; Tanaka, Y; Tainaka, T; Shirota, C; Sumida, W; Makita, S; Takimoto, A; Nakamura, M; Fujishiro, M; Hinoki, A; Uchida, H

    BMC SURGERY   Vol. 20 ( 1 ) page: 317   2020.12

     More details

  77. The microbiome can predict mucosal healing in small intestine in patients with Crohn's disease

    Hattori, S; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Yamamoto, K; Ishikawa, T; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Hirooka, Y; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 12 ) page: 1138 - 1149   2020.12

     More details

  78. Accuracy of carbon dioxide insufflation for endoscopic retrograde cholangiopancreatography using double-balloon endoscopy

    Niwa, Y; Nakamura, M; Kawashima, H; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ishikawa, T; Kakushima, N; Furukawa, K; Ohno, E; Honda, T; Ishigami, M; Fujishiro, M

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 26 ( 42 ) page: 6669 - 6678   2020.11

     More details

  79. Mutation analysis of gastrointestinal stromal tumors using RNA obtained via endoscopic ultrasound-guided fine-needle aspiration

    Funasaka, K; Miyahara, R; Furukawa, K; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Hirooka, Y; Ohmiya, N; Fujishiro, M

    TRANSLATIONAL ONCOLOGY   Vol. 13 ( 11 ) page: 100848   2020.11

     More details

  80. Endoscopic Activity and Serum TNF-α Level at Baseline Are Associated With Clinical Response to Ustekinumab in Crohn's Disease Patients

    Murate, K; Maeda, K; Nakamura, M; Sugiyama, D; Wada, H; Yamamura, T; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Miyahara, R; Ishigami, M; Nishikawa, H; Fujishiro, M

    INFLAMMATORY BOWEL DISEASES   Vol. 26 ( 11 ) page: 1669 - 1681   2020.11

     More details

  81. Computer-aided diagnosis for characterization of colorectal lesions: comprehensive software that includes differentiation of serrated lesions

    Pu, LZCT; Maicas, G; Tian, Y; Yamamura, T; Nakamura, M; Suzuki, H; Singh, G; Rana, K; Hirooka, Y; Burt, AD; Fujishiro, M; Carneiro, G; Singh, R

    GASTROINTESTINAL ENDOSCOPY   Vol. 92 ( 4 ) page: 891 - 899   2020.10

     More details

  82. Comparison of different virtual chromoendoscopy classification systems for the characterization of colorectal lesions

    Pu, LZCT; Yamamura, T; Nakamura, M; Koay, DSC; Ovenden, A; Edwards, S; Burt, AD; Hirooka, Y; Fujishiro, M; Singh, R

    JGH OPEN   Vol. 4 ( 5 ) page: 818 - 826   2020.10

     More details

  83. Low ETV1 mRNA expression is associated with recurrence in gastrointestinal stromal tumors

    Sakamaki, K; Funasaka, K; Miyahara, R; Furukawa, K; Yamamura, T; Ohno, E; Nakamura, M; Kawashima, H; Hirooka, Y; Fujishiro, M; Goto, H

    SCIENTIFIC REPORTS   Vol. 10 ( 1 ) page: 14767   2020.9

     More details

  84. Reappraisal of Primary Epstein-Barr Virus (EBV)-positive Diffuse Large B-Cell Lymphoma of the Gastrointestinal Tract Comparative Analysis Among Immunosuppressed and Nonimmunosuppressed Stage I and II-IV Patients

    Miyagi, S; Ishikawa, E; Nakamura, M; Shimada, K; Yamamura, T; Furukawa, K; Tanaka, T; Mabuchi, S; Tsuyuki, Y; Kohno, K; Sakakibara, A; Satou, A; Kato, S; Fujishiro, M; Nakamura, S

    AMERICAN JOURNAL OF SURGICAL PATHOLOGY   Vol. 44 ( 9 ) page: 1173 - 1183   2020.9

     More details

  85. Learning curve for mastery of colorectal endoscopic submucosal dissection: Perspectives from a large Japanese cohort

    Pu, LZCT; Yamamura, T; Nakamura, M; Esaki, M; Kaosombatwattana, U; Rodriguez, MR; Edwards, S; Burt, AD; Singh, R; Hirooka, Y; Fujishiro, M

    JGH OPEN   Vol. 4 ( 4 ) page: 611 - 616   2020.8

     More details

  86. Polyp Detection Rate as a Surrogate for Adenoma and Sessile Serrated Adenoma/Polyp Detection Rates

    Pu, LZCT; Singh, G; Rana, K; Nakamura, M; Yamamura, T; Krishnamurthi, S; Ovenden, A; Edwards, S; Ruszkiewicz, A; Hirooka, Y; Fujishiro, M; Burt, AD; Singh, R

    GASTROINTESTINAL TUMORS   Vol. 7 ( 3 ) page: 74 - 82   2020.7

     More details

  87. Use of Immunostaining for the diagnosis of Lymphovascular invasion in superficial Barrett's esophageal adenocarcinoma

    Hosono, I; Miyahara, R; Furukawa, K; Funasaka, K; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Yokoi, T; Hirooka, Y; Fujishiro, M; Tsukamoto, T

    BMC GASTROENTEROLOGY   Vol. 20 ( 1 ) page: 175   2020.6

     More details

  88. PROSPECTIVE MULTICENTER STUDY ON THE USEFULNESS OF EUS-GUIDED FINE NEEDLE BIOPSY FOR THE DIAGNOSIS OF AUTOIMMUNE PANCREATITIS USING A 22-GAUGE FRANSEEN NEEDLE

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Keiko Maeda, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB172 - AB172   2020.6

     More details

  89. PROSPECTIVE MULTICENTER STUDY ON THE USEFULNESS OF EUS-GUIDED FINE NEEDLE BIOPSY FOR THE DIAGNOSIS OF AUTOIMMUNE PANCREATITIS USING A 22-GAUGE FRANSEEN NEEDLE

    Ishikawa, T; Kawashima, H; Ohno, E; Nishio, R; Iida, T; Suzuki, H; Uetsuki, K; Yamada, K; Yashika, J; Yoshikawa, M; Gibo, N; Aoki, T; Kataoka, K; Mori, H; Keiko, M; Sawada, T; Yamamura, T; Furukawa, K; Nakamura, M; Fujishiro, M

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB172 - AB172   2020.6

     More details

  90. NOVEL METHOD TO DETERMINE THE DEPTH OF INVASION IN COLORECTAL NEOPLASMS WITH ULTRASOUND ELASTOGRAPHY USING A FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE

    Esaki Masaya, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Kentaro, Hasegawa Issei, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB430 - AB430   2020.6

     More details

  91. NOVEL METHOD TO DETERMINE THE DEPTH OF INVASION IN COLORECTAL NEOPLASMS WITH ULTRASOUND ELASTOGRAPHY USING A FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE

    Esaki, M; Yamamura, T; Nakamura, M; Keiko, M; Sawada, T; Mizutani, Y; Kuno, T; Yamada, K; Hasegawa, I; Ishikawa, T; Furukawa, K; Ohno, E; Kawashima, H; Fujishiro, M

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB430 - AB430   2020.6

     More details

  92. EVALUATION OF RESECTABILITY BETWEEN ENDOSCOPIC TREATMENT METHODS FOR RECTAL NEUROENDOCRINE TUMOR

    Toriyama Kazuhiro, Yamamura Takeshi, Nakamura Masanao, Keiko Maeda, Sawada Tsunaki, Mizutani Yasuyuki, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB101 - AB101   2020.6

     More details

  93. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Sawada Tsunaki, Keiko Maeda, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB618 - AB618   2020.6

     More details

  94. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Sawada Tsunaki, Keiko Maeda, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB618 - AB618   2020.6

     More details

  95. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS

    Furukawa, K; Miyahara, R; Funasaka, K; Sawada, T; Keiko, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Fujishiro, M

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB618 - AB618   2020.6

     More details

  96. EVALUATION OF RESECTABILITY BETWEEN ENDOSCOPIC TREATMENT METHODS FOR RECTAL NEUROENDOCRINE TUMOR

    Toriyama, K; Yamamura, T; Nakamura, M; Keiko, M; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Kawashima, H; Fujishiro, M

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 6 ) page: AB101 - AB101   2020.6

     More details

  97. Nonexposed wall-inversion surgery as a novel local resection method for neoplasms in the gastrointestinal tract

    Fujishiro, M; Furukawa, K; Yamamura, T; Nakamura, M; Honda, T; Maeda, O; Ishigami, M; Kawashima, H

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page: 175 - 182   2020.5

     More details

  98. Narrow-band imaging for scar (NBI-SCAR) classification: from conception to multicenter validation

    Pu, LZCT; Chiam, KH; Yamamura, T; Nakamura, M; Berzin, TM; Mir, FF; de Moura, EGH; Neto, ACM; Koay, DSC; Loong, CK; Ovenden, A; Edwards, S; Burt, AD; Hirooka, Y; Fujishiro, M; Singh, R

    GASTROINTESTINAL ENDOSCOPY   Vol. 91 ( 5 ) page: 1146 - +   2020.5

     More details

  99. Different factors are associated with conventional adenoma and serrated colorectal neoplasia

    Pu, LZCT; Rana, K; Singh, G; Nakamura, M; Yamamura, T; Koay, DSC; Ovenden, A; Edwards, S; Ruszkiewicz, A; Hirooka, Y; Fujishiro, M; Burt, AD; Singh, R

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 2 ) page: 335 - 343   2020.5

     More details

  100. Clinical Factors Associated with Missing Colorectal Polyp on Colon Capsule Endoscopy

    Yamada, K; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Hotta, N; Hirooka, Y

    DIGESTION   Vol. 101 ( 3 ) page: 316 - 322   2020.5

     More details

  101. An International Study on the Diagnostic Accuracy of the Japan Narrow-Band Imaging Expert Team Classification for Colorectal Polyps Observed with Blue Laser Imaging

    Suzuki, H; Yamamura, T; Nakamura, M; Hsu, CM; Su, MY; Chen, TH; Chiu, CT; Hirooka, Y; Goto, H

    DIGESTION   Vol. 101 ( 3 ) page: 339 - 346   2020.5

     More details

  102. Double-balloon endoscopic retrograde cholangiopancreatography for patients who underwent liver operation: A retrospective study

    Nishio, R; Kawashima, H; Nakamura, M; Ohno, E; Ishikawa, T; Yamamura, T; Maeda, K; Sawada, T; Tanaka, H; Sakai, D; Miyahara, R; Ishigami, M; Hirooka, Y; Fujishiro, M

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 26 ( 10 ) page: 1056 - 1066   2020.3

     More details

  103. Microbiota profile is different for early and invasive colorectal cancer and is consistent throughout the colon

    Pu, LZCT; Yamamoto, K; Honda, T; Nakamura, M; Yamamura, T; Hattori, S; Burt, AD; Singh, R; Hirooka, Y; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 35 ( 3 ) page: 433 - 437   2020.3

     More details

  104. Usefulness of Endoscopic Ultrasound Elastography Combined With the Strain Ratio in the Estimation of Treatment Effect in Autoimmune Pancreatitis

    Ishikawa, T; Kawashima, H; Ohno, E; Tanaka, H; Maeda, K; Sawada, T; Yamamura, T; Furukawa, K; Nakamura, M; Miyahara, R; Ishigami, M; Fujishiro, M

    PANCREAS   Vol. 49 ( 2 ) page: E21 - E22   2020.2

  105. Magnetic anchor-guided endoscopic submucosal dissection for colorectal tumors (with video)

    Matsuzaki, I; Hattori, M; Yamauchi, H; Goto, N; Iwata, Y; Yokoi, T; Tsunemi, M; Kobayashi, M; Yamamura, T; Miyahara, R

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 34 ( 2 ) page: 1012 - 1018   2020.2

     More details

  106. Prognostic impact of PD-L1 expression in primary gastric and intestinal diffuse large B-cell lymphoma

    Ishikawa, E; Nakamura, M; Shimada, K; Tanaka, T; Satou, A; Kohno, K; Sakakibara, A; Furukawa, K; Yamamura, T; Miyahara, R; Nakamura, S; Kato, S; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY   Vol. 55 ( 1 ) page: 39 - 50   2020.1

     More details

  107. Generation of magnifying endoscopic images of gastric neoplasms based on an all-in-focus algorithm

    Matsui, K; Funasaka, K; Miyahara, R; Furukawa, K; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Ohara, K; Hirooka, Y; Goto, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 35 ( 1 ) page: 65 - 70   2020.1

     More details

  108. Endoscopic detorsion using single-balloon endoscopy for cecal volvulus

    Suzuki, H; Yamamura, T; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 32 ( 1 ) page: 149 - 149   2020.1

     More details

  109. Color information from linked color imaging is associated with invasion depth and vascular diameter in superficial esophageal squamous cell carcinoma

    Kobayashi, K; Miyahara, R; Funasaka, K; Furukawa, K; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Nakaguro, M; Okumura, Y; Hirooka, Y; Fujishiro, M

    DIGESTIVE ENDOSCOPY   Vol. 32 ( 1 ) page: 65 - 73   2020.1

     More details

  110. Refractory Ulcerative Colitis Improved by Scheduled Combination Therapy of Vedolizumab and Granulocyte and Monocyte Adsorptive Apheresis

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, E; Ohashi, A; Kajikawa, G; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    INTERNAL MEDICINE   Vol. 59 ( 23 ) page: 3009 - 3014   2020

     More details

  111. A Prospective Study of Factors Associated with Abdominal Pain in Patients during Unsedated Colonoscopy Using a Magnifying Endoscope

    Suzuki, H; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Honda, T; Kawashima, H; Ishigami, M; Fujishiro, M

    INTERNAL MEDICINE   Vol. 59 ( 15 ) page: 1795 - 1801   2020

     More details

  112. Nasal patency as a factor for successful transnasal endoscopy

    Nagaya, T; Miyahara, R; Funasaka, K; Furukawa, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Nakashima, T; Nakata, S; Hirooka, Y

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 4 ) page: 587 - 595   2019.11

     More details

  113. The relationship between portal hypertension and the microbiome

    Yamamoto, K; Honda, T; Hattori, S; Pu, LZCT; Ito, T; Yamamura, T; Ishizu, Y; Kuzuya, T; Ishigami, M; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 106 - 107   2019.9

     More details

  114. Prospective study assessing a comprehensive computer-aided diagnosis for characterization of colorectal lesions: Results from different centers and imaging technologies

    Pu L. Zorron Cheng Tao, Maicas G., Tian Y., Yamamura T., Singh G., Rana K., Suzuki H., Nakamura M., Hirooka Y., Burt A., Fujishiro M., Carneiro G., Singh R.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 25 - 26   2019.9

     More details

  115. Prospective study assessing a comprehensive computer-aided diagnosis for characterization of colorectal lesions: Results from different centers and imaging technologies

    Pu, LZCT; Maicas, G; Tian, Y; Yamamura, T; Singh, G; Rana, K; Suzuki, H; Nakamura, M; Hirooka, Y; Burt, A; Fujishiro, M; Carneiro, G; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 25 - 26   2019.9

     More details

  116. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori, S; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Yamamoto, K; Pu, LZCT; Honda, T; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 152 - 152   2019.9

     More details

  117. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori, S; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Yamamoto, K; Pu, LZCT; Honda, T; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 152 - 152   2019.9

     More details

  118. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori S., Nakamura M., Yamamura T., Maeda K., Sawada T., Mizutani Y., Yamamoto K., Pu L. Zorron Cheng Tao, Honda T., Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 152 - 152   2019.9

     More details

  119. Objective evaluation of the therapeutic effect of ustekinumab on Crohn's disease

    Yamamura T., Nakamura M., Murate K., Maeda K., Sawada T., Mizutani Y., Nishikawa T., Hattori S., Yamamoto K., Pu L. Zorron Cheng Tao, Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 145 - 145   2019.9

     More details

  120. Learning curve for mastery of colorectal endoscopic submucosal dissection: Perspectives from a Japanese cohort of more than 500 procedures

    Pu, LZCT; Yamamura, T; Kaosombatwattana, U; Esaki, M; Edwards, MNS; Edwards, S; Burt, A; Hirooka, Y; Singh, R; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 20 - 21   2019.9

     More details

  121. Microbiota profile is markedly different for early and invasive colorectal cancer and is consistent throughout the colon

    Pu L. Zorron Cheng Tao, Yamamoto K., Honda T., Hattori S., Nakamura M., Yamamura T., Burt A., Hirooka Y., Singh R., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 40 - 41   2019.9

     More details

  122. Microbiota profile is markedly different for early and invasive colorectal cancer and is consistent throughout the colon

    Pu, LZCT; Yamamoto, K; Honda, T; Hattori, S; Nakamura, M; Yamamura, T; Burt, A; Hirooka, Y; Singh, R; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 40 - 41   2019.9

     More details

  123. Modified Sano's classification is the most accurate for characterizing serrated polyps and adenomas with different virtual chromoendoscopy methods: Results of a prospective observational study

    Pu L. Zorron Cheng Tao, Yamamura T., Nakamura M., Koay D., Ovenden A., Edwards S., Hirooka Y., Burt A., Fujishiro M., Singh R.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 226 - 227   2019.9

     More details

  124. Modified Sano's classification is the most accurate for characterizing serrated polyps and adenomas with different virtual chromoendoscopy methods: Results of a prospective observational study

    Pu, LZCT; Yamamura, T; Nakamura, M; Koay, D; Ovenden, A; Edwards, S; Hirooka, Y; Burt, A; Fujishiro, M; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 226 - 227   2019.9

     More details

  125. Narrow-band imaging for scar (NBI-SCAR) classification: From conception to multicenter validation

    Pu, LZCT; Chiam, K; Yamamura, T; Nakamura, M; Berzin, T; Mir, F; De Moura, E; Neto, AM; Koay, D; Loong, C; Ovenden, A; Edwards, S; Hirooka, Y; Fujishiro, M; Burt, A; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 227 - 228   2019.9

     More details

  126. Objective evaluation of the therapeutic effect of ustekinumab on Crohn's disease

    Yamamura, T; Nakamura, M; Murate, K; Maeda, K; Sawada, T; Mizutani, Y; Nishikawa, T; Hattori, S; Yamamoto, K; Pu, LZCT; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Fujishiro, M

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34   page: 145 - 145   2019.9

     More details

  127. THE PROPAGATION DISPLAY METHOD IMPROVES THE REPRODUCIBILITY OF PANCREATIC SHEAR WAVE ELASTOGRAPHY

    Hashizume, K; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Kawai, M; Suhara, H; Takeyama, T; Koya, T; Tanaka, H; Sakai, D; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Ishigami, M; Kuwahara, T; Hashimoto, S; Goto, H

    ULTRASOUND IN MEDICINE AND BIOLOGY   Vol. 45 ( 8 ) page: 2242 - 2247   2019.8

     More details

  128. USEFULNESS OF THE FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE IN THE DIAGNOSIS OF INVASION DEPTH OF COLORECTAL NEOPLASIA

    Kuno, T; Yamamura, T; Nakamura, M; Maeda, K; Sawada, T; Mizutani, Y; Suzuki, H; Esaki, M; Ishikawa, T; Furukawa, K; Ohno, E; Kawashima, H; Miyahara, R; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB324 - AB324   2019.6

  129. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB608 - AB608   2019.6

  130. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno, E; Hirooka, Y; Kawashima, H; Ishikawa, T; Tanaka, H; Sakai, D; Iida, T; Nishio, R; Suzuki, H; Uetsuki, K; Yashika, J; Yamada, K; Yoshikawa, M; Gibo, N; Aoki, T; Yamamura, T; Furukawa, K; Nakamura, M; Miyahara, R

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB608 - AB608   2019.6

  131. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB608 - AB608   2019.6

  132. USEFULNESS OF THE FORWARD-VIEWING RADIAL-ARRAY ECHOENDOSCOPE IN THE DIAGNOSIS OF INVASION DEPTH OF COLORECTAL NEOPLASIA

    Kuno Takeshi, Yamamura Takeshi, Nakamura Masanao, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Suzuki Hiroto, Esaki Masaya, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Kawashima Hiroki, Miyahara Ryoji, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB324 - AB324   2019.6

  133. FACTORS RELATED TO MISSED COLORECTAL POLYPS ON COLON CAPSULE ENDOSCOPY IN CLINICAL PRACTICE

    Yamada, K; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Niwa, Y; Ishikawa, E; Otsuka, H; Suzuki, H; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Hotta, N; Pu, LZCT; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB155 - AB155   2019.6

  134. FACTORS RELATED TO MISSED COLORECTAL POLYPS ON COLON CAPSULE ENDOSCOPY IN CLINICAL PRACTICE

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Pu Leonardo Zorron Cheng Tao, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB155 - AB155   2019.6

  135. FACTORS RELATED TO MISSED COLORECTAL POLYPS ON COLON CAPSULE ENDOSCOPY IN CLINICAL PRACTICE

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Pu Leonardo Zorron Cheng Tao, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB155 - AB155   2019.6

  136. CLINICAL SIGNIFICANCE OF THE PATENCY OF GASTROINTESTINAL TRACT IN CROHN'S DISEASE EVALUATED BY PATENCY CAPSULE

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Kuno, T; Yamada, K; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB333 - AB333   2019.6

  137. CLINICAL SIGNIFICANCE OF THE PATENCY OF GASTROINTESTINAL TRACT IN CROHN'S DISEASE EVALUATED BY PATENCY CAPSULE

    Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Kuno Takeshi, Yamada Keisaku, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY   Vol. 89 ( 6 ) page: AB333 - AB333   2019.6

  138. The utility of ultrathin endoscopy with flexible spectral imaging color enhancement for early gastric cancer

    Yokoyama, T; Miyahara, R; Funasaka, K; Furukawa, K; Yamamura, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Hirooka, Y; Hirakawa, A; Goto, H

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 2 ) page: 241 - 248   2019.5

     More details

  139. Effect of time of day and specialty on polyp detection rates in Australia

    Pu, LZCT; Lu, K; Ovenden, A; Rana, K; Singh, G; Krishnamurthi, S; Edwards, S; Wilson, B; Nakamura, M; Yamamura, T; Ruszkiewicz, A; Hirooka, Y; Burt, AD; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 34 ( 5 ) page: 899 - 906   2019.5

     More details

  140. Colorectal endoscopic submucosal dissection in special locations

    Kaosombatwattana, U; Yamamura, T; Nakamura, M; Hirooka, Y; Goto, H

    WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY   Vol. 11 ( 4 ) page: 262 - 270   2019.4

     More details

  141. Preoperative endoscopic predictors of severe submucosal fibrosis in colorectal tumors undergoing endoscopic submucosal dissection

    Kaosombatwattana, U; Yamamura, T; Limsrivilai, J; Nakamura, M; Leelakusolvong, S; Hirooka, Y; Goto, H

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 7 ( 4 ) page: E421 - E430   2019.4

     More details

  142. Utility of linked color imaging for endoscopic diagnosis of early gastric cancer

    Fujiyoshi, T; Miyahara, R; Funasaka, K; Furukawa, K; Sawada, T; Maeda, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Nakaguro, M; Nakatochi, M; Hirooka, Y

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 25 ( 10 ) page: 1248 - 1258   2019.3

     More details

  143. Plummer-Vinson Syndrome with Esophageal Web Formation in which Detailed Endoscopic Images Were Obtained

    Hirose, T; Funasaka, K; Furukawa, K; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Miyahara, R; Hirooka, Y

    INTERNAL MEDICINE   Vol. 58 ( 6 ) page: 785 - 789   2019

     More details

  144. Lewis Score on Capsule Endoscopy as a Predictor of the Risk for Crohn's Disease-Related Emergency Hospitalization and Clinical Relapse in Patients with Small Bowel Crohn's Disease

    Nishikawa, T; Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Miyahara, R; Kawashima, H; Hirooka, Y

    GASTROENTEROLOGY RESEARCH AND PRACTICE   Vol. 2019   page: 4274257   2019

     More details

  145. Clinical Impact of EUS-Guided Fine Needle Biopsy Using a Novel Franseen Needle for Histological Assessment of Pancreatic Diseases

    Ishikawa, T; Kawashima, H; Ohno, E; Tanaka, H; Sakai, D; Iida, T; Nishio, R; Yamamura, T; Furukawa, K; Nakamura, M; Miyahara, R; Hashimoto, S; Ishigami, M; Hirooka, Y

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 2019   page: 8581743   2019

     More details

  146. Clinicopathological analysis of primary intestinal diffuse large B-cell lymphoma: Prognostic evaluation of CD5, PD-L1, and Epstein-Barr virus on tumor cells

    Ishikawa, E; Kato, S; Shimada, K; Tanaka, T; Suzuki, Y; Satou, A; Kohno, K; Sakakibara, A; Yamamura, T; Nakamura, M; Miyahara, R; Goto, H; Nakamura, S; Hirooka, Y

    CANCER MEDICINE   Vol. 7 ( 12 ) page: 6051 - 6063   2018.12

     More details

  147. Validity of Capsule Endoscopy in Monitoring Therapeutic Interventions in Patients with Crohn's Disease

    Nakamura, M; Yamamura, T; Maeda, K; Sawada, T; Mizutani, Y; Ishikawa, T; Furukawa, K; Ohno, E; Kawashima, H; Miyahara, R; Koulaouzidis, A; Hirooka, Y

    JOURNAL OF CLINICAL MEDICINE   Vol. 7 ( 10 )   2018.10

     More details

  148. Prospective study predicting histology in colorectal lesions using wNICE, wJNET, and MS classifications

    Pu, LZCT; Yamamura, T; Nakamura, M; Koay, DSC; Ovenden, A; Edwards, S; Hoong, CK; Burt, AD; Hirooka, Y; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 14 - 14   2018.9

     More details

  149. Prevalence and distribution of serrated polyps in the colon

    Pu, LZCT; Singh, G; Krishnamurthi, S; Ovenden, A; Nakamura, M; Yamamura, T; Rana, K; Lu, K; Edwards, S; Ruszkiewicz, A; Hoong, CK; Hirooka, Y; Burt, A; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 185 - 186   2018.9

     More details

  150. Prospective study assessing associated factors in patients with colorectal lesions

    Pu, LZCT; Ovenden, A; Nakamura, M; Yamamura, T; Sawada, T; Koay, DSC; Edwards, S; Hoong, CK; Burt, AD; Hirooka, Y; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 186 - 186   2018.9

     More details

  151. Effect of training and time of the day on polyp detection rates

    Pu, LZCT; Lu, K; Ovenden, A; Rana, K; Singh, G; Krishnamurthi, S; Edwards, S; Wilson, B; Nakamura, M; Yamamura, T; Ruszkiewicz, A; Hoong, CK; Hirooka, Y; Burt, AD; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 184 - 185   2018.9

     More details

  152. Effect of training and time of the day on polyp detection rates

    Pu, LZCT; Lu, K; Ovenden, A; Rana, K; Singh, G; Krishnamurthi, S; Edwards, S; Wilson, B; Nakamura, M; Yamamura, T; Ruszkiewicz, A; Hoong, CK; Hirooka, Y; Burt, AD; Singh, R

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 184 - 185   2018.9

     More details

  153. Objective evaluation of blood flow in the small-intestinal villous: quantification of findings from dynamic endoscopy with concomitant narrow-band imaging.

    Takeyama T, Hirooka Y, Kawashima H, Ohno E, Ishikawa T, Yamamura T, Furukawa K, Funasaka K, Nakamura M, Miyahara R, Ishigami M, Goto H

    Endoscopy international open   Vol. 6 ( 8 ) page: E941 - E949   2018.8

     More details

    Language:English  

    DOI: 10.1055/a-0619-4965

    PubMed

  154. Increase in breath hydrogen concentration was correlated with the main pancreatic duct stenosis

    Sakai, D; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Suhara, H; Takeyama, T; Koya, T; Tanaka, H; Iida, T; Nishio, R; Suzuki, H; Uetsuki, K; Matsushita, M; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Ishigami, M; Tsuruta, A; Shin, W; Goto, H

    JOURNAL OF BREATH RESEARCH   Vol. 12 ( 3 ) page: 036004   2018.7

     More details

  155. USEFULNESS OF HISTOLOGICAL ASSESSMENT WITH EUS-GUIDED FINE NEEDLE BIOPSY USING A NEW CORE NEEDLE IN PANCREATIC DISEASES

    Ishikawa, T; Hirooka, Y; Kawashima, H; Ohno, E; Suhara, H; Takeyama, T; Koya, T; Tanaka, H; Sakai, D; Nishio, R; Iida, T; Suzuki, H; Uetsuki, K; Matsushita, M; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB432 - AB433   2018.6

     More details

  156. PROSPECTIVE STUDY OF SMALL BOWEL CAPSULE ENDOSCOPY FOR EVALUATING THE THERAPEUTIC EFFECTS IN PATIENTS WITH CROHN'S DISEASE

    Nakamura, M; Hirooka, Y; Watanabe, O; Yamamura, T; Matsushita, M; Suhara, H; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Koulaouzidis, A; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB393 - AB393   2018.6

     More details

  157. THE DIAGNOSTIC ABILITY AND PITFALL OF JNET(JAPAN NBI EXPERT TEAM)CLASSIFICATION IN TRAINEES

    Suzuki, H; Yamamura, T; Watanabe, O; Nakamura, M; Matsushita, M; Sawada, T; Mizutani, Y; Ishikawa, E; Niwa, Y; Uchida, G; Otsuka, H; Nishikawa, T; Ishida, T; Yamada, K; Hattori, S; Kajikawa, G; Hashiguchi, H; Suhara, H; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB489 - AB490   2018.6

     More details

  158. USEFULLNESS OF CONTRAST-ENHANCED HARMONIC EUS(CH-EUS) FOR THE PREOPERATIVE ASSESSMENT OF MPD INVOLVEMENT IN IPMN; A RETROSPECTIVE COMPARISON STUDY OF CH-EUS AND IDUS

    Ohno, E; Hirooka, Y; Kawashima, H; Ishikawa, T; Suhara, H; Takeyama, T; Koya, T; Tanaka, H; Sakai, D; Nishio, R; Iida, T; Suzuki, H; Uetsuki, K; Matsushita, M; Furukawa, K; Yamamura, T; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB426 - AB427   2018.6

     More details

  159. OUTCOMES AND PREDICTORS OF SEVERE SUBMUCOSAL FIBROSIS IN COLORECTAL ENDOSCOPIC SUBMUCOSAL DISSECTION

    Kaosombatwattana, U; Yamamura, T; Limsrivilai, J; Watanabe, O; Nakamura, M; Matsushita, M; Suhara, H; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Miyahara, R; Kawashima, H; Leelakusolvong, S; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB377 - AB377   2018.6

     More details

  160. EVALUATION OF LOCAL RECURRENCE AFTER COLD POLYPECTOMY COMPARED WITH CONVENTIONAL HOT POLYPECTOMY IN A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL

    Yamamura, T; Saito, M; Watanabe, O; Nakamura, M; Matsushita, M; Sawada, T; Mizutani, Y; Niwa, Y; Ishikawa, E; Suzuki, H; Otsuka, H; Uchida, G; Nishikawa, T; Ishida, T; Kuno, T; Yamada, K; Hattori, S; Hashiguchi, H; Suhara, H; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Miyahara, R; Kawashima, H; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB478 - AB478   2018.6

     More details

  161. DIAGNOSTIC IMAGING SYSTEM WITH VIRTUAL ENTEROSCOPY AND COMPUTER-AIDED DETECTION FOR EVALUATION OF SMALL BOWEL LESIONS OF CROHN'S DISEASE

    Furukawa, K; Miyahara, R; Funasaka, K; Suhara, H; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Oda, M; Mori, K; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB304 - AB304   2018.6

     More details

  162. ENDOSCOPIC TREATMENT FOR SUPERFICIAL NON-AMPULLARY DUODENAL TUMORS

    Furukawa, K; Miyahara, R; Funasaka, K; Suhara, H; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 87 ( 6 ) page: AB315 - AB316   2018.6

     More details

  163. Functional Correlation Between the Pancreas and the Small Intestine in Humans: The First Evaluation Using a Newly Developed Enteroscopy

    Hayashi, D; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Kuwahara, T; Kawai, M; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Ishigami, M; Hashimoto, S; Goto, H

    PANCREAS   Vol. 47 ( 5 ) page: 601 - 608   2018.5

  164. Fecal calprotectin reflects endoscopic activity in patients with small-bowel Crohn's disease according to double-balloon endoscopy findings

    Matsuura, R; Watanabe, O; Nakamura, M; Yamamura, T; Matsushita, M; Suhara, H; Furukawa, K; Ishikawa, T; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Hirooka, Y; Goto, H

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 2 ) page: 257 - 266   2018.5

     More details

  165. Nomogram-based prediction of rebleeding in small bowel bleeding patients: the 'PRSBB' score

    Uchida, G; Hirooka, Y; Nakamura, M; Watanabe, O; Yamamura, T; Matsushita, M; Suhara, H; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 6378   2018.4

     More details

  166. Usefulness of shear wave elastography as a quantitative diagnosis of chronic pancreatitis

    Kuwahara, T; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Ishigami, M; Hashimoto, S; Goto, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33 ( 3 ) page: 756 - 761   2018.3

     More details

  167. Clinical significance of gastrointestinal patency evaluation by using patency capsule in Crohn's disease

    Yoshimura, T; Hirooka, Y; Nakamura, M; Watanabe, O; Yamamura, T; Matsushita, M; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 1 ) page: 121 - 128   2018.2

     More details

  168. Endoscopic ultrasound in diagnosis of solid pancreatic lesions: Elastography or contrast-enhanced harmonic alone versus the combination.

    Chantarojanasiri T, Hirooka Y, Kawashima H, Ohno E, Kuwahara T, Yamamura T, Funasaka K, Nakamura M, Miyahara R, Ishigami M, Watanabe O, Hashimoto S, Hirakawa A, Ratanachu-Ek T, Goto H

    Endoscopy international open   Vol. 5 ( 11 ) page: E1136 - E1143   2017.11

     More details

    Language:English  

    DOI: 10.1055/s-0043-118829

    PubMed

  169. Development and validation of a new scoring system to determine the necessity of small-bowel endoscopy in obscure gastrointestinal bleeding

    Uchida, G; Nakamura, M; Watanabe, O; Yamamura, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    DIGESTIVE AND LIVER DISEASE   Vol. 49 ( 11 ) page: 1218 - 1224   2017.11

     More details

  170. <i>In vivo</i> histological diagnosis for gastric cancer using endocytoscopy

    Tsurudome, I; Miyahara, R; Funasaka, K; Furukawa, K; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Nakaguro, M; Satou, A; Hirooka, Y; Goto, H

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 23 ( 37 ) page: 6894 - 6901   2017.10

     More details

  171. Making decision to treat with infliximab by the result of periodic surveillance with double-balloon endoscopy after ilectomy can obtain mucosal healing and avoid re-operation on patients with Crohn's disease for a long-term follow-up study

    Watanabe, O; Nakamura, M; Yamamura, T; Matsushita, M; Saito, M; Matsuura, R; Sawada, T; Mizutani, Y; Niwa, Y; Ishikawa, E; Uchida, G; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Yamada, K; Kuno, T; Hattori, S; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Miyahara, R; Kawashima, H; Hirooka, Y; Goto, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 32   page: 287 - 287   2017.9

     More details

  172. ETV1 expression would be a predictive marker of malignancy in GIST

    Funasaka, K; Miyahara, R; Furukawa, K; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Hirooka, Y; Goto, H

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 32   page: 79 - 80   2017.9

     More details

  173. Clinical factors related to false-positive rates of patency capsule examination

    Sawada, T; Nakamura, M; Watanabe, O; Yamamura, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY   Vol. 10 ( 8 ) page: 589 - 598   2017.8

     More details

  174. Quantitative diagnosis of chronic pancreatitis using EUS elastography

    Kuwahara, T; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Kawai, M; Suhara, H; Takeyama, T; Hashizume, K; Koya, T; Tanaka, H; Sakai, D; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Ishigami, M; Hashimoto, S; Goto, H

    JOURNAL OF GASTROENTEROLOGY   Vol. 52 ( 7 ) page: 868 - 874   2017.7

     More details

  175. Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction

    Ishiguro, K; Watanabe, O; Nakamura, M; Yamamura, T; Matsushita, M; Goto, H; Hirooka, Y

    CLINICAL IMMUNOLOGY   Vol. 180   page: 120 - 127   2017.7

     More details

  176. Combinational use of lipid-based reagents for efficient transfection of primary fibroblasts and hepatoblasts

    Ishiguro, K; Watanabe, O; Nakamura, M; Yamamura, T; Matsushita, M; Goto, H; Hirooka, Y

    BIOTECHNIQUES   Vol. 63 ( 1 ) page: 37 - 39   2017.7

     More details

  177. The Study of Diagnostic Ability for the Colorectal Neoplasms by Imaged Enhanced Endoscopy Using by JNET (Japan NBI Expert Team) Classification

    Yamamura, T; Watanabe, O; Nakamura, M; Matsushita, M; Oshima, H; Sato, J; Matsuura, R; Saito, M; Mizutani, Y; Sawada, T; Niwa, Y; Ishikawa, E; Uchida, G; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB402 - AB402   2017.5

  178. The Outcome of Treatment in Hypopharyngeal and Cervical Esophageal Carcinoma

    Fujiyoshi, T; Miyahara, R; Funasaka, K; Furukawa, K; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB597 - AB598   2017.5

  179. Predicting the Depth of Invasion of Esophageal Squamous Cell Carcinoma: Under Experience of Linked Colored Imaging With LED Light Source

    Kobayashi, K; Miyahara, R; Funasaka, K; Furukawa, K; Matsushita, M; Yamamura, T; Ishikawa, T; Ohno, E; Nakamura, M; Kawashima, H; Watanabe, O; Hirooka, Y; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB527 - AB527   2017.5

  180. Novel EMR Technique for Preoperative Diagnosis and Treatment of Submucosal Tumor in the Small Bowel at Double-Balloon Endoscopy

    Nakamura, M; Watanabe, O; Yamamura, T; Matsushita, M; Oshima, H; Sato, J; Saito, M; Matsuura, R; Mizutani, Y; Sawada, T; Niwa, Y; Ishikawa, E; Uchida, G; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB300 - AB300   2017.5

  181. Objective Assessment of Jejunal Villous Blood Flow for Evaluating Pancreas-Jejunum Functional Correlation Using a Novel Image Analyzing System

    Takeyama, T; Hirooka, Y; Kawashima, H; Ohno, E; Ishikawa, T; Kawai, M; Suhara, H; Hashizume, K; Koya, T; Tanaka, H; Sakai, D; Matsushita, M; Yamamura, T; Furukawa, K; Funasaka, K; Nakamura, M; Miyahara, R; Watanabe, O; Goto, H

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB319 - AB320   2017.5

  182. One Year Follow-Up After Cold Polypectomy Compared With Hot Polypectomy for Small Colorectal Polyps - a Prospective Randomized Controlled Trial

    Saito, M; Yamamura, T; Watanabe, O; Nakamura, M; Matsushita, M; Oshima, H; Sato, J; Matsuura, R; Mizutani, Y; Sawada, T; Niwa, Y; Ishikawa, E; Uchida, G; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB365 - AB366   2017.5

  183. Establishment of a New Scoring System for Predicting the Necessity of Double-Balloon Endoscopy in Obscure Gastrointestinal Bleeding

    Uchida, G; Watanabe, O; Nakamura, M; Yamamura, T; Matsushita, M; Oshima, H; Sato, J; Saito, M; Matsuura, R; Mizutani, Y; Sawada, T; Niwa, Y; Ishikawa, E; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB300 - AB300   2017.5

  184. Clinical Factors Related to False Positive Rates of Patency Capsule Examination

    Sawada, T; Nakamura, M; Watanabe, O; Yamamura, T; Matsushita, M; Oshima, H; Sato, J; Saito, M; Matsuura, R; Mizutani, Y; Niwa, Y; Ishikawa, E; Uchida, G; Otsuka, H; Suzuki, H; Nishikawa, T; Ishida, T; Ishikawa, T; Furukawa, K; Funasaka, K; Ohno, E; Miyahara, R; Kawashima, H; Goto, H; Hirooka, Y

    GASTROINTESTINAL ENDOSCOPY   Vol. 85 ( 5 ) page: AB305 - AB305   2017.5

  185. Comparison of the diagnostic ability of blue laser imaging magnification versus pit pattern analysis for colorectal polyps.

    Nakano A, Hirooka Y, Yamamura T, Watanabe O, Nakamura M, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H

    Endoscopy international open   Vol. 5 ( 4 ) page: E224 - E231   2017.4

     More details

    Language:English  

    DOI: 10.1055/s-0043-102400

    PubMed

  186. Specific characteristics of hemorrhagic Meckel's diverticulum at double-balloon endoscopy.

    Mizutani Y, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Murino A, Goto H Professor, Hirooka Y

    Endoscopy international open   Vol. 5 ( 1 ) page: E35 - E40   2017.1

     More details

    Language:English  

    DOI: 10.1055/s-0042-119810

    PubMed

  187. Prospective study of factors important to achieve observation of the entire colon on colon capsule endoscopy

    Sato, J; Nakamura, M; Watanabe, O; Yamamura, T; Funasaka, K; Ohno, E; Miyahara, R; Kawashima, H; Goto, H; Hirooka, Y

    THERAPEUTIC ADVANCES IN GASTROENTEROLOGY   Vol. 10 ( 1 ) page: 20 - 31   2017.1

     More details

  188. Endoscopic Characteristics, Risk Grade, and Prognostic Prediction in Gastrointestinal Stromal Tumors of the Small Bowel

    Nakano, A; Nakamura, M; Watanabe, O; Yamamura, T; Funasaka, K; Ohno, E; Kawashima, H; Miyahara, R; Goto, H; Hirooka, Y

    DIGESTION   Vol. 95 ( 2 ) page: 122 - 131   2017

     More details

  189. Dexmedetomidine provides less body motion and respiratory depression during sedation in double-balloon enteroscopy than midazolam.

    Oshima H, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y

    SAGE open medicine   Vol. 5   page: 2050312117729920   2017

     More details

    Language:English  

    DOI: 10.1177/2050312117729920

    PubMed

  190. [Risk factors for rebleeding and risk-based follow-up of obscure gastrointestinal bleeding after its initial diagnosis].

    Uchida G, Nakamura M, Watanabe O, Yamamura T, Matsushita M, Ishikawa T, Furukawa K, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H, Hirooka Y

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   Vol. 114 ( 10 ) page: 1819 - 1829   2017

     More details

    Language:Japanese  

    DOI: 10.11405/nisshoshi.114.1819

    PubMed

  191. Effectiveness of Endoscopic Ultrasonography during Double Balloon Enteroscopy for characterization and management of small bowel submucosal tumours. Reviewed

    Murino A, Nakamura M, Watanabe O, Yamamura T, Nagura A, Yoshimura T, Nakano A, Goto H, Hirooka Y

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver   Vol. 48 ( 10 ) page: 1187-93   2016.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.dld.2016.06.026

    PubMed

  192. Evaluation of radiation exposure dose at double-balloon endoscopy for the patients with small bowel disease. Reviewed

    Nagura A, Nakamura M, Watanabe O, Yamamura T, Funasaka K, Ohno E, Miyahara R, Kawashima H, Koyama S, Hinami T, Goto H, Hirooka Y

    Nagoya journal of medical science   Vol. 78 ( 3 ) page: 245-53   2016.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  193. Evaluation of the mRNA and Protein Expressions of Nutritional Biomarkers in the Gastrointestinal Mucosa of Patients with Small Intestinal Disorders. Reviewed

    Nakamura M, Hirooka Y, Watanabe O, Yamamura T, Funasaka K, Ohno E, Miyahara R, Kawashima H, Shimoyama Y, Goto H

    Internal medicine (Tokyo, Japan)   Vol. 55 ( 16 ) page: 2145-52   2016

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/internalmedicine.55.6781

    PubMed

  194. A Retrospective Evaluation of the Utility of Capsule Endoscopy and Double-Balloon Endoscopy in Crohn's Disease. Reviewed

    Nakamura M, Hirooka Y, Watanabe O, Yamamura T, Funasaka K, Ohno E, Kawashima H, Miyahara R, Goto H

    Gastroenterology research and practice   Vol. 2016   page: 1085027   2016

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2016/1085027

    PubMed

  195. Utility of endoscopic diagnosis for postoperative small-bowel lesions in patients with Crohn's disease at double-balloon endoscopy. Reviewed

    Yamada K, Hirooka Y, Watanabe O, Nakamura M, Yamamura T, Funasaka K, Ohno E, Miyahara R, Kawashima H, Goto H

    Nagoya journal of medical science   Vol. 77 ( 3 ) page: 409-15   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  196. Clinical usefulness of novel tag-less Agile patency capsule prior to capsule endoscopy for patients with suspected small bowel stenosis. Reviewed

    Nakamura M, Hirooka Y, Yamamura T, Miyahara R, Watanabe O, Ando T, Ohmiya N, Goto H

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   Vol. 27 ( 1 ) page: 61-6   2015.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/den.12306

    PubMed

  197. Cowden syndrome complicated by a gastrointestinal stromal tumor. Reviewed

    Nakamura M, Hirooka Y, Yamamura T, Yamada K, Nagura A, Yoshimura T, Ohmiya N, Uehara K, Yoshioka Y, Nagino M, Goto H

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society   Vol. 26 ( 5 ) page: 673-5   2014.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/den.12167

    PubMed

  198. Steroid-resistant Cronkhite-Canada syndrome successfully treated by cyclosporine and azathioprine. Reviewed

    Ohmiya N, Nakamura M, Yamamura T, Yamada K, Nagura A, Yoshimura T, Hirooka Y, Matsumoto T, Hirata I, Goto H

    Journal of clinical gastroenterology   Vol. 48 ( 5 ) page: 463-4   2014.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MCG.0000000000000009

    PubMed

  199. Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition. Reviewed

      Vol. 59 ( 4 ) page: 1591-9   2014.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/hep.26930

    PubMed

  200. Management of small-bowel polyps in Peutz-Jeghers syndrome by using enteroclysis, double-balloon enteroscopy, and videocapsule endoscopy. Reviewed

    Ohmiya N, Nakamura M, Takenaka H, Morishima K, Yamamura T, Ishihara M, Miyahara R, Kawashima H, Itoh A, Hirooka Y, Watanabe O, Ando T, Goto H

    Gastrointestinal endoscopy   Vol. 72 ( 6 ) page: 1209-16   2010.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.gie.2010.08.018

    PubMed

▼display all

Presentations 10

  1. FACTORS RELATED TO MISSED COLORECTAL POLYPS ON COLON CAPSULE ENDOSCOPY IN CLINICAL PRACTICE

    Yamada Keisaku, Nakamura Masanao, Yamamura Takeshi, Maeda Keiko, Sawada Tsunaki, Mizutani Yasuyuki, Niwa Yoshiki, Ishikawa Eri, Otsuka Hiroyuki, Suzuki Hiroto, Ishikawa Takuya, Furukawa Kazuhiro, Ohno Eizaburo, Miyahara Ryoji, Kawashima Hiroki, Hotta Naoki, Pu Leonardo Zorron Cheng Tao, Hirooka Yoshiki

    GASTROINTESTINAL ENDOSCOPY  2019.6 

  2. USEFULLNESS OF EUS-GUIDED SHEAR-WAVE MEASUREMENT (EUS-SWM) FOR THE ASSESSMENT OF ACTIVITIES OF AUTOIMMUNE PANCREATITIS; A PROSPECTIVE EXPLORATORY STUDY

    Ohno Eizaburo, Hirooka Yoshiki, Kawashima Hiroki, Ishikawa Takuya, Tanaka Hiroyuki, Sakai Daisuke, Iida Tadashi, Nishio Ryo, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yamada Kenta, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Miyahara Ryoji

    GASTROINTESTINAL ENDOSCOPY  2019.6 

  3. The relationship between portal hypertension and the microbiome

    Yamamoto K., Honda T., Hattori S., Pu L. Zorron Cheng Tao, Ito T., Yamamura T., Ishizu Y., Kuzuya T., Ishigami M., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2019.9 

  4. Specific members of gut microbiota predict mucosal healing in Crohn's disease

    Hattori S., Nakamura M., Yamamura T., Maeda K., Sawada T., Mizutani Y., Yamamoto K., Pu L. Zorron Cheng Tao, Honda T., Ishikawa T., Furukawa K., Ohno E., Miyahara R., Kawashima H., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2019.9 

  5. Prospective study assessing a comprehensive computer-aided diagnosis for characterization of colorectal lesions: Results from different centers and imaging technologies

    Pu L. Zorron Cheng Tao, Maicas G., Tian Y., Yamamura T., Singh G., Rana K., Suzuki H., Nakamura M., Hirooka Y., Burt A., Fujishiro M., Carneiro G., Singh R.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2019.9 

  6. PROSPECTIVE MULTICENTER STUDY ON THE USEFULNESS OF EUS-GUIDED FINE NEEDLE BIOPSY FOR THE DIAGNOSIS OF AUTOIMMUNE PANCREATITIS USING A 22-GAUGE FRANSEEN NEEDLE

    Ishikawa Takuya, Kawashima Hiroki, Ohno Eizaburo, Nishio Ryo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yamada Kenta, Yashika Jun, Yoshikawa Masakatsu, Gibo Noriaki, Aoki Toshinori, Kataoka Kunio, Mori Hiroshi, Keiko Maeda, Sawada Tsunaki, Yamamura Takeshi, Furukawa Kazuhiro, Nakamura Masanao, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY  2020.6 

  7. Modified Sano's classification is the most accurate for characterizing serrated polyps and adenomas with different virtual chromoendoscopy methods: Results of a prospective observational study

    Pu L. Zorron Cheng Tao, Yamamura T., Nakamura M., Koay D., Ovenden A., Edwards S., Hirooka Y., Burt A., Fujishiro M., Singh R.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2019.9 

  8. Microbiota profile is markedly different for early and invasive colorectal cancer and is consistent throughout the colon

    Pu L. Zorron Cheng Tao, Yamamoto K., Honda T., Hattori S., Nakamura M., Yamamura T., Burt A., Hirooka Y., Singh R., Fujishiro M.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2019.9 

  9. ENDOSCOPIC DIAGNOSIS USING MAGNIFYING IMAGE-ENHANCED ENDOSCOPY FOR SUPERFICIAL NON-AMPULLARY DUODENAL EPITHELIAL TUMORS

    Furukawa Kazuhiro, Miyahara Ryoji, Funasaka Kohei, Sawada Tsunaki, Keiko Maeda, Yamamura Takeshi, Ishikawa Takuya, Ohno Eizaburo, Nakamura Masanao, Kawashima Hiroki, Fujishiro Mitsuhiro

    GASTROINTESTINAL ENDOSCOPY  2020.6 

  10. Effect of training and time of the day on polyp detection rates

    Pu L. Zorron Cheng Tao, Lu K., Ovenden A., Rana K., Singh G., Krishnamurthi S., Edwards S., Wilson B., Nakamura M., Yamamura T., Ruszkiewicz A., Hoong C. K., Hirooka Y., Burt A. D., Singh R.

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY  2018.9 

▼display all

Research Project for Joint Research, Competitive Funding, etc. 1

  1. 大腸内視鏡における画像強調昨日LCI(Lincked color imaging)の有用性に関する臨床研究

      More details

    Authorship:Principal investigator  Grant type:Competitive

KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. クローン病術後抗TNFα抗体維持療法の有効性と安全性に関する検討

    Grant number:22K08768  2022.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    中山 吾郎, 山村 健史, 梅田 晋一, 中村 正直, 服部 憲史

      More details

    Authorship:Coinvestigator(s) 

    クローン病は小腸・大腸を中心とした消化管に慢性肉芽腫性炎症を生じる原因不明の炎症性腸疾患であり,厚生労働省より特定疾患(指定難病)に指定されている.現在クローン病を完治させる治療法はなく,薬物治療により活動性をコントロールし,患者のQoLを高めることが治療の主体である.一方で腸管切除を含む手術が必要となる症例も多く,また術後再発による再手術率が高いことは大きな問題である.本研究では難治性腸管病変に対する手術後の寛解維持療法としての生物学的製剤の再発抑制効果と安全性を臨床第2相試験として検証し,科学的根拠に基づく新たな治療戦略を創世することを目標とする.
    クローン病は小腸・大腸を中心とした消化管に慢性肉芽腫性炎症を生じる原因不明の炎症性腸疾患であり、厚生労働省より特定疾患に指定されている。現在クローン病を完治させる治療法はなく、薬物治療により活動性をコントロールし、患者のQoLを高めることが治療の主体である。一方で腸管切除を含む手術が必要となる症例も多く、また術後再発による再手術率が高いことは大きな問題である。本研究では難治性腸管病変に対する手術後の寛解維持療法としての生物学的製剤の再発抑制効果と安全性を臨床第2相試験として検証し、科学的根拠に基づく新たな治療戦略を創世することを目標とする。
    当施設の炎症性腸疾患治療センターを中心に内科・外科共同でクローン病の難治性腸管病変に対する術後ウステキヌマブ寛解維持療法の有効性と安全性について評価を行った。2022年度は、過去に当院でクローン病に対する腸管切除・吻合術後にウステキヌマブが投与された患者のうち、術前に抗TNF-α抗体薬の投与歴があるクローン病患者(コホートA)16例、術前に抗TNF-α抗体薬の投与歴がないクローン病患者(コホートB)11例を対象として、術後1年の臨床的再発に関して後方視的に検討を行い、本研究の妥当性について検討を行った。各コホートの再発率は、19%/10%と良好であり、この結果をもとに本研究の実施計画書を作成した。2023年度は研究実施計画書を名古屋大学医学部附属病院IRBへ提出し、認可を取得の上で症例登録を開始する(予定登録数50例)。
    2022年度は、本研究の妥当性の検証及び名古屋大学医学部附属病院IRBに提出する研究実施計画書作成を目的とし、historical dataを用いた後方視的検討を行い、本研究の実施計画書を作成した。
    2023年度は研究実施計画書を名古屋大学医学部附属病院IRBへ提出し、認可を取得の上で症例登録を開始する(予定登録数50例)。プロトコール治療(術後、2-4 週の期間にウステキヌマブを開始し、原則内視鏡的もしくは臨床的な再発が確認されるまで継続)及び内視鏡的評価を含むフォローアップは、研究代表者及び研究分担者を中心に実施する。2024年度には、主要評価項目である術後1年内視鏡的吻合部再発率について、2025年度には副次的評価項目(臨床的再発率,再手術率,各無再発生存期間,治療成功期間,有害事象発生割合等)について適宜評価・解析を行い、関連学会や論文において結果を公表する。

  2. 炎症性腸疾患における新規粘膜関連細菌叢検出法を用いた腸粘膜炎症プロファイルの作成

    Grant number:20K07801  2020.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    中村 正直, 本多 隆, 山村 健史, 川嶋 啓揮, 藤城 光弘

      More details

    Authorship:Coinvestigator(s) 

    炎症性腸疾患の腸表面の粘膜関連細菌叢から粘膜固有層までの免疫増幅経路は同時に同部位で評価すべき事象である。同じ部位の内視鏡生検検体を用いて、A)粘膜関連細菌叢の最適検出法を見出したうえで採取、細菌16SrRNA次世代シークエンス解析を行う。B)生検組織のフローサイトメトリーによる免疫担当細胞とT細胞の分布解析、細胞内炎症性サイトカインの定量を行い、免疫応答をカテゴリー化する。C)粘膜内蛋白質量解析により、炎症反応のKeyとなる分子の量と種類につき網羅的に解析する。A)B)C)から得た結果を疾患活動性とリンクさせ、腸粘膜炎症プロファイルを作成する。
    20名の潰瘍性大腸炎患者において大腸内視鏡時に回腸末端、盲腸、直腸の生検組織、腸粘液を採取した検体について、腸炎の活動性と各炎症マーカー、神経ー免疫系にかかわる測定項目について既報を基に研究分担者と選定中である。
    追加で潰瘍性大腸炎患者3名の大腸内視鏡時における腸粘液をサンプルとし発症、再燃増悪に関連する因子の同定を目的とした。適切な検体採取の整合性を評価後、採取サンプル(炎症有無部位での比較)の網羅的解析を行った。独自の方法を用いて粘液層採取及びRNA抽出を行い、粘液層でのbulkのRNA seqを行った。ネットカテーテルによる粘液採取ではRNA抽出初期にネット自体が試薬内に溶け出し順調に進まなかったため、この実験は全てブラシ鉗子を用いて行った。腸粘液のRNAシークエンス実現性につき採取、抽出されたRNAの濃度、純度を測定しRNAシークエンスが可能と判断した。RNAシークエンスについてはraw dataから解析(QC, mapping, quantification, clustering, DE analysis, functional enrichment)を施行した際に神経伝達に関わる因子が複数指摘された。また我々の粘液層でのdata解析結果と、public dataの腸管上皮のRNA seqの解析結果を比較した。粘液層と腸管粘膜の網羅的解析結果を比較すると神経伝達に関連する因子が同定され、これらの因子が炎症に関与する可能性を考慮した。候補となった神経伝達因子については粘液内、粘膜内における存在をリアルタイムPCRで確認し、その各々が潰瘍性大腸炎の寛解期、活動期のいずれかで影響が大きいか調べた。
    大腸内視鏡によるサンプル採取方法の調整については、既報が無かったため時間を要し、更に測定項目の選定に時間を要したため全体の進行としてはやや遅れている。
    サンプル採取調整が終わり、現在はサンプル採取方法、実験系は確立できたため現在のペースで進めることができれば研究を完遂できると考えている。

  3. 焦点調節画像を用いた新規大腸腫瘍診断の解析と治療への応用

    Grant number:19K20667  2019.4 - 2024.3

    科学研究費助成事業  若手研究

    山村 健史

      More details

    Authorship:Principal investigator 

    Grant amount:\3770000 ( Direct Cost: \2900000 、 Indirect Cost:\870000 )

    増加する大腸癌の診療において、大腸内視鏡は必要不可欠である。適切な診断と最適な治療方法を決定するために、狭帯域光観察(NBI)やpit pattern診断を高い正診率で行うことが重要であるが、主観に頼らざるを得ない内視鏡診断においては、診断能にバラツキが生じてしまう。本研究では、内視鏡画面全体に焦点の最適化を行った焦点調節画像を作成し、その特殊画像を用いることにより大腸腫瘍の診断能の向上を図る。また焦点調節画像を統合することにより、腫瘍の2Dマッピングや3D画像構築を行い内視鏡治療に活用することで治療成績の向上を図る。
    2019年度に様々な大腸腫瘍の内視鏡観察法で焦点調節画像を試し、白色光観察やpit pattern観察よりもImaged enhanced endoscopy拡大観察が最も本方法の条件に合致していると考えられた。また撮影法も動かす速度や画像の取り方などを色々と試し、最適な条件を決定した。
    次に撮影技術固定されたところで作成した焦点調節画像が内視鏡医に与える影響に関して検討した。具体的に作成した画像を動画と静止画単位で視認性や診断能の検討を行い、どこまで診断能が向上し得るかを評価した。初学者と熟練者に分け、それぞれを主観的評価と客観的評価に分けて検証した。その結果、客観的評価である診断精度(正診率など)は初学者と熟練者共に焦点調節画像になっても有意な改善は認めなかったが、主観的評価(読影結果の信頼度・画像の質の評価など)は両者で有意に改善した。また診断時間も同様に両者で改善した。以上より、焦点調節画像が内視鏡医に与える影響は主観的評価の向上であることが明らかとなった。これまでの結果については現在、論文投稿中である。
    3D構築については2020年度に試行したところ、画像を構築することは可能となった。ただし精密な図を作成するには、現技術ではまだ精度に問題があることが判明し、画像をマッチングさせる特徴点を大幅に増量し、それらを高速処理で処理時間を増やさない技術を名城大学と共同で開発していた。しかしコロナ蔓延による影響で相互の交流停止となる事情があり開発が遅れている。現在再度構築のプログラムを模索中である。
    3D構築については、前技術ではまだ精度に問題があり、評価は困難と判断した。動画の特徴点を大幅に増量し、それらを高速処理で処理時間を増やすことのない技術を名城大学と共同で開発しようとしているが、コロナ蔓延による活動停止時期などがあり十分な成果を得るに至っていない。現在は違うアプローチからの方法も模索している。
    現在、焦点調節画像が内視鏡医に与える影響に関しては成果を得ており論文投稿を進めている。
    今後の研究の方向としては、3D構築を可能とする方法の確立を目標としている。以前の画像をマッチングさせる特徴点を大幅に増量し、それらを高速処理で処理時間を増やすことなく3D構築を可能とする方法だと特徴点を合わせる部分で、対象の移動距離により正確性にやや難があることが分かった。ハレーションを除去する技術を進めたが、それ単独では良好な画像を作り出すことは困難であった。そのため特徴点を増やすことにより、同一物体のずれをより正確に感知し、3D化することを目指している。また別の方法も模索をしている。3D画像が構築可能となれば、実際の内視鏡手技において周囲(襞や蠕動による変形)との関係を3D画像構築することで、事前の有用な情報となりうる。