Updated on 2022/04/27

写真a

 
DAMNJANOVIC Jasmina
 
Organization
Graduate School of Bioagricultural Sciences Department of Applied Biosciences Lecturer
Graduate School
Graduate School of Bioagricultural Sciences
Undergraduate School
School of Agricultural Sciences Department of Applied Biosciences
Title
Lecturer
Contact information
メールアドレス

Degree 1

  1. Doctor of Agriculture ( 2013.9   Nagoya University ) 

Research Interests 5

  1. Enzymology

  2. Protein engineering

  3. in vitro screening

  4. cDNA display

  5. Directed evolution

Research Areas 1

  1. Life Science / Applied biochemistry  / Applied biochemistry

Current Research Project and SDGs 1

  1. Development of enzymes for sustainable life

Research History 4

  1. Nagoya University   Nagoya University Graduate School of Bioagricultural Sciences   Lecturer

    2020.9

  2. Nagoya University   Graduate School of Bioagricultural Sciences Department of Bioengineering Sciences Department of Bioengineering Sciences   Assistant Professor

    2015.3 - 2020.8

  3. Nagoya University   Graduate School of Bioagricultural Sciences Department of Bioengineering Sciences Department of Bioengineering Sciences   Designated assistant professor

    2014.3 - 2015.3

  4. Nagoya University   Graduate School of Bioagricultural Sciences Department of Bioengineering Sciences Department of Bioengineering Sciences   Researcher

    2013.10 - 2014.2

Education 1

  1. Nagoya University   Graduate School of Bioagricultural Sciences   PhD

    2010.10 - 2013.9

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    Country: Japan

Professional Memberships 2

  1. Japan Society for Bioscience, Biotechnology and Agrochemistry

  2. The Society for Biotechnology, Japan

Committee Memberships 3

  1. Women Leaders Program to Promote Well-being in Asia   Executive committee member for Women Leaders Program to Promote Well-being in Asia  

    2021   

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    Committee type:Other

  2. The Society for Biotechnology Japan   Bioinformatics consultation forum Steering comittee member  

    2017   

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    Committee type:Academic society

  3. Women Leaders Program to Promote Well-being in Asia   Organizing committee member for Women Leaders Program to Promote Well-being in Asia  

    2015   

Awards 3

  1. Best Poster Award

    2014.11   13th China-Japan-Korea Joint Symposium on Enzyme Engineering  

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    Country:Korea, Republic of

  2. Chubu Branch Chief Award

    2013.8   The Society for Biotechnology, Japan, Chubu affiliate regular meeting  

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    Country:Japan

  3. MEXT Scholarship

    2009.10   Ministry of Education, Culture, Sports, Science and Technology, Japan  

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    Country:Japan

 

Papers 19

  1. Structures of an engineered phospholipase D with specificity for secondary alcohol transphosphatidylation: insights into plasticity of substrate binding and activation Reviewed International coauthorship

    Samantha Ariela, Damnjanovic Jasmina, Iwasaki Yugo, Nakano Hideo, Vrielink Alice

    Biochemical Journal   Vol. 478 ( 9 ) page: 1749 - 1767   2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  2. A simple chemo-enzymatic synthesis of alkyl-acyl (plasmanyl) phospholipids Reviewed

    Iwasaki Yugo, Sakurai Yuuki, Damnjanovic Jasmina

    Biocatalysis and Agricultural Biotechnology   Vol. 26   page: 101625   2020.7

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bcab.2020.101625

    Web of Science

  3. cDNA display coupled with next-generation sequencing for rapid activity-based screening: Comprehensive analysis of transglutaminase substrate preference

    Damnjanović Jasmina, Odake Nana, Fan Jicheng, Jia Beixi, Kojima Takaaki, Nemoto Naoto, Hitomi Kiyotaka, Nakano Hideo

    bioRxiv     2021.9

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (other academic)  

    DOI: https://doi.org/10.1101/2021.09.08.459404

    DOI: https://doi.org/10.1101/2021.09.08.459404

  4. Synthesis of difficult-tosynthesize phospholipids with modified phospholipase D Invited Reviewed

    Iwasaki Yugo, Damnjanović Jasmina

    Biotechnology   Vol. 98 ( 9 ) page: 481 - 484   2020

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    Authorship:Last author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  5. Production of active manganese peroxidase in Escherichia coli by co-expression of chaperones and in vitro maturation by ATP-dependent chaperone release Reviewed

    Alfi Almasul, Zhu Bo, Damnjanovic Jasmina, Kojima Takaaki, Iwasaki Yugo, Nakano Hideo

    Journal of Bioscience and Bioengineering   Vol. 128 ( 3 ) page: 290 - 295   2019.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2019.02.011

    Web of Science

    PubMed

  6. Application of molecular docking simulation in biotechnology (in Japanese) Invited

    Damnjanović J., and Iwasaki Y.

    Biotechnology (in Japanese)   Vol. 97 ( 5 ) page: 257-260   2019.8

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  7. Acyl chain that matters: Introducing sn-2 acyl chain preference to a phospholipase D by protein engineering Reviewed

    Damnjanović, J., Nakano, H., and Iwasaki, Y.

    Protein Engineering Design and Seection   Vol. 32   page: 1-11   2019.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  8. SKIK-zipbody-alkaline phosphatase, a novel antibody fusion protein expressed in Escherichia coli cytoplasm Reviewed

    Ritthisan P., Ojima-Kato T., Damnjanovic J., Kojima T., Nakano H.

    Journal of Bioscience and Bioengineering   Vol. 126 ( 6 ) page: 705-709   2018.12

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    Language:English   Publishing type:Research paper (scientific journal)  

  9. Facile enzymatic synthesis of phosphatidylthreonine using an engineered phospholipase D Reviewed

    Damnjanovic J., Matsunaga N., Adachi M., Nakano H., Iwasaki Y.

    European Journal of Lipid Science and Technology   Vol. 120 ( 1800089 ) page: 1-7   2018.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  10. Direct enzymatic synthesis of 1-phosphatidyl-β-D-glucose by engineered phospholipase D Reviewed

    Inoue A., Adachi M., Damnjanovic J., Nakano H., and Iwasaki Y.

    Chemistry Select   Vol. 1   page: 4121-4125   2016.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  11. Salt-induced increase in the yield of enzymatically synthesized phosphatidylinositol and the underlying mechanism Reviewed

    Muraki M., Damnjanovic J., Nakano H., and Iwasaki Y.

    Journal of Bioscence and Bioengineering   Vol. 122 ( 3 ) page: 276-282   2016.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  12. Directing positional specificity in enzymatic synthesis of bioactive 1-phosphatidylinositol by protein engineering of a phospholipase D Reviewed

    Damnjanovic J., Kuroiwa C., Tanaka H., Ishida K., Nakano H., Iwasaki Y.

    Biotechnology and Bioengineering   Vol. 113 ( 1 ) page: 62-71   2015.9

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  13. Deletion of a dynamic surface loop improves stability and changes kinetic behavior of phosphatidylinositol-synthesizing Streptomyces phospholipase D Reviewed

    Damnjanovic J., Nakano H. and Iwasaki Y.

    Biotechnology and Bioengineering   Vol. 111   page: 674-682   2014.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  14. Phospholipase D as a catalyst: application in phospholipid synthesis, molecular structure and protein engineering Invited Reviewed

    Damnjanovic J. and Iwasaki Y.

    Journal of Bioscience and Bioengineering   Vol. 116   page: 271-280   2013.9

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    Authorship:Lead author   Language:English  

  15. Simple and efficient profiling of phospholipids in phospholipase D-modified soy lecithin by HPLC with charged aerosol detection Reviewed

    Damnjanovic J., Nakano H., Iwasaki Y.

    Journal of the American Oil Chemists Society   Vol. 90   page: 951-957   2013.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  16. Improving thermostability of phosphatidylinositol-synthesizing, Streptomyces phospholipase D Reviewed

    Damnjanovic J., Takahashi R., Nakano H., Iwasaki Y.

    Protein Engineering, Design & Selection   Vol. 25   page: 415-424   2012.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  17. Covalently immobilized lipase catalyzing high-yielding optimized geranyl butyrate synthesis in a batch and fluidized bed reactor Reviewed

    Damnjanovic J., Zuza M., Savanovic J., Bezbradica D., Mijin D., Boskovic- Vragolovic N., Knezevic-Jugovic Z

    Journal of Molecular Catalysis B: Enzymatic   Vol. 75   page: 50-59   2011.11

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  18. The immobilization of lipase on Sepabeads®: Coupling, characterization and application in geranyl-butyrate synthesis in a low aqueous system Reviewed

    Knezevic Z., Damnjanovic J., Bezbradica D., Mijin D.

    Chemical Industry & Chemical Engineering Quarterly   Vol. 14   page: 245-249   2008.11

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    Language:English   Publishing type:Research paper (scientific journal)  

  19. Covalent immobilization of lipase from Candida rugosa on Eupergit® Reviewed

    Bezbradica D., Corovic J., Prodanovic R., Milosavic N, Knezevic Z.

    Acta Periodica Technologica   Vol. 36   page: 179-186   2005.11

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 2

  1. Chapter 3: Enzymatic modification of phospholipids. in "Recent Advances in Biotechnology Vol. 4. Progress in Food Biotechnology" (Ali Osman, ed.)

    Jasmina Damnjanovic, Yugo Iwasaki( Role: Joint author)

    Bentham Science  2018 

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    Language:English Book type:Scholarly book

  2. Chapter 4: Enzymatic Modification of Phospholipids by Phospholipase D. in "Lipid Modification by Enzymes and Engineered Microbes" (U.T. Bornscheuer, ed.)

    Jasmina Damnjanovic, Yugo Iwasaki( Role: Joint author)

    AOCS press  2018 

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    Language:English Book type:Scholarly book

Presentations 12

  1. cDNA display coupled with next-generation sequencing for rapid activity-based screening: Analysis of transglutaminase substrate preference International conference

    Jasmina Damnjanovic, Nana Odake1, Takaaki Kojima, Naoto Nemoto, Kiyotaka Hitomi, Hideo Nakano

    The 3rd Aachen Protein Engineering Symposium (AcES)  European Federation of Biotechnology

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    Event date: 2022.9

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Aachen (online)   Country:Germany  

  2. Comprehensive analysis of transglutaminase substrate preference by cDNA display

    Damnjanovic Jasmina,Nezu Moeri,Jia Beixi,Odake Nana,Hitomi Kiyotaka,Kojima Takaaki,Nemoto Naoto,Nakano Hideo

    The 2022 Annual Meeting of the Japan Society for Bioscience, Biotechnology and Agrochemistry  2022.3.18  Japan Society for Bioscience, Biotechnology and Agrochemistry

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    Event date: 2022.3

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Kyoto (online)  

  3. cDNA display coupled with next-generation sequencing for activity-based selection: Comprehensive analysis of transglutaminase substrate preference

    Damnjanovic Jasmina, Odake Nana, Kojima Takaaki, Nemoto Naoto, Hitomi Kiyotaka, Nakano Hideo

    2021 Sakura-Bio Meeting  2021.5.29  The Society for Biotechnology Japan, Chubu branch

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    Event date: 2021.5

    Language:English   Presentation type:Oral presentation (general)  

  4. Novel cDNA display platform for activity-based selection in protein engineering

    Damnjanovic Jasmina, Odake Nana, Kojima Takaaki, Nemoto Naoto, Nakano Hideo

    Annual Meeting of Japan Society of Bioscience, Biotechnology and Agrochemistry 2020  2021.3.21  Japan Society of Bioscience, Biotechnology and Agrochemistry

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    Event date: 2021.3

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Sendai (online)  

  5. Comprehensive analysis of transglutaminase 1 substrate preferences using cDNA display

    T.I.K Munaweera, Jasmina Damnjanovic, Moeri Nezu, Maurizio Camagna, Takaaki Kojima, Kiyotaka Hitomi, Hideo Nakano

    The first report meeting of Amano Enzyme research fund  Amano Enzyme

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    Event date: 2022.3

    Language:English   Presentation type:Oral presentation (general)  

  6. The reaction mechanism of microbial phospholipase D

    Iwamoto Haruka, Goto Tomoaki, Damnjanovic Jasmina, Nakano Hideo, Iwasaki Yugo

    Annual Meeting of Japan Society of Bioscience, Biotechnology and Agrochemistry 2021  2021.3.20  Japan Society of Bioscience, Biotechnology and Agrochemistry

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  7. Functional studies and protein engineering of industrially-relevant enzymes Invited International conference

    Jasmina Damnjanovic

    Bayliss seminar   2020.3.5  School of Molecular Sciences, University of Western Australia

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    Event date: 2020.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:School of Molecular Sciences, University of Western Australia   Country:Australia  

  8. Protein engineering of phospholipase D for enzymatic synthesis of bioactive phospholipids Invited

    Jasmina Damnjanovic, Nozomi Matsunaga, Michiko Muraki, Arisa Inoue, Hideo Nakano, Yugo Iwasaki

    2nd Research Meeting of Genome-Epigenome Research Project 

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    Event date: 2017.12

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  9. Directing positional specificity in phospholipase D-catalyzed synthesis of 1-phosphatidylinositol

    Jasmina Damnjanovic, Chisato Kuroiwa, Ken Ishida, Hidetoshi Tanaka, Michiko Muraki, Hideo Nakano, Yugo Iwasaki

    2015 Joint Chubu-Kansai Meeting of the Japan Society for Bioscience, Biotechnology and Agrochemistry 

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    Event date: 2015.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  10. Deletion of a dynamic loop as a rational strategy to improve stability of phospholipase D

    Damnjanovic Jasmina, Nakano Hideo, Iwasaki Yugo

    Annual Meeting of the Society for Biotechnology Japan, Chubu branch 

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  11. Surface loop deletion as a strategy for enzyme thermostabilization

    Damnjanovic Jasmina, Nakano Hideo, Iwasaki Yugo

    90th Anniversary Meeting/64th Annual Meeting of the Society for Biotechnology Japan 

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    Event date: 2012.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  12. Influence of surface loop (D40) deletion on expression and stability of Streptomyces antibioticus phospholipase D

    Damnjanovic Jasmina, Nakano Hideo, Iwasaki Yugo

    Annual meeting of Japan Society of Bioscience, Biotechnology and Agrochemistry 

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    Event date: 2012.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 1

  1. Engineering phospholipase D for novel substrate specificity and catalytic chemistry International coauthorship

    2018.1 - 2020.3

    International Cooperative Research 

    Damnjanovic Jasmina, Vrielink Alice, Iwasaki Yugo, Hideo Nakano

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\2312504

    The project aims to elucidate how the engineered enzyme, phospholipase D (PLD), recognizes and accommodates bulky substrates in a specific orientation to preferably afford certain positional isomers of rare phospholipids, and to understand whether PLD utilizes an alternative catalytic mechanism in the synthesis of cyclic phospholipids.
    This research is important since it will provide entirely new knowledge on structure-function relationship of PLD, valuable for the synthesis of bioactive, but otherwise unavailable, phospholipids. Since enzymatic synthesis is advantageous to other methods in terms of cost, yield, and specificity, we expect increased availability of rare and unnatural phospholipids for both, research and industry. This will foster further discovery into the roles and functions of phospholipids in the human body and will assist in drug development, since the same catalytic mechanism of PLD is shared among many enzymes with key functions in humans and microorganisms, such as endonucleases, ribonucleases, and kinases.

KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. Development of cDNA display platform for selection of enzymes in enzyme engi neering

    Grant number: 22K14828  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grant-in-Aid for Scientific Research  

    Damnjanovic Jasmina

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3640000 ( Direct Cost: \2800000 、 Indirect Cost:\840000 )

  2. Development of novel monoclonal antibody creation system using AI and single cell technoogy

    Grant number:19H02523  2019.4 - 2023.3

    Japan Society for the Promotion of Science  Grant-in-Aid for Scientific Research  

    Nakano Hideo

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  3. Development of single molecule display platform for directed evolution of enzymes

    Grant number:18K14387  2018.4 - 2022.3

    Japan Society for the Promotion of Science  Grant-in-Aid for Scientific Research  

    Damnjanovic Jasmina

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

 

Teaching Experience (On-campus) 22

  1. Biotechnology for G30 (COIL with North Carolina State University)

    2021

  2. Special Lecture on Multicultural Societies

    2021

  3. Laboratory training in organic chemistry

    2021

  4. Bioagricultural practice 4

    2020

  5. Bioagricultural practice 3

    2020

  6. Bioagricultural practice 2

    2020

  7. Bioagricultural practice 1

    2020

  8. Biomolecular engineering

    2020

  9. Laboratory training in organic chemistry

    2020

  10. Special Lecture on Multicultural Societies

    2020

  11. Biotechnology Science V

    2018

  12. Laboratory course in Organic chemistry

    2018

  13. Cell Biology II

    2018

  14. Introduction to Information Literacy

    2017

  15. Biotechnology Science V

    2017

  16. Laboratory course in Organic chemistry

    2017

  17. Fundamentals of Biology I

    2017

  18. Introduction to Information Literacy

    2016

  19. Biotechnology Science V

    2016

  20. Laboratory course in Organic chemistry

    2016

  21. Biotechnology Science V

    2015

  22. Laboratory course in Organic chemistry

    2015

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Teaching Experience (Off-campus) 1

  1. Biotechnology for G30 (COIL with North Carolina State University)

    2021.10 - 2021.11 North Carolina State University)

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    Level:Undergraduate (liberal arts)  Country:United States

 

Social Contribution 2

  1. 2021 Sakura-Bio meeting

    Role(s):Organizing member

    The Society for Biotechnology, Japan, Chubu branch  2021.5

  2. 2020 Sakura-Bio meeting

    Role(s):Organizing member

    The Society for Biotechnology, Japan, Chubu branch  2020.3

Academic Activities 4

  1. International Journal of Biological Macromolecules International contribution

    Role(s):Peer review

    2022.1

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    Type:Peer review 

  2. FEBS Open Bio International contribution

    Role(s):Peer review

    2020.10 - 2021.2

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    Type:Peer review 

  3. Journal of Bioscience and Bioengineering

    Role(s):Peer review

    2019.5

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    Type:Peer review 

  4. Bioscience, Biotechnology, and Biochemistry International contribution

    Role(s):Peer review

    2019.2

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    Type:Peer review