Updated on 2021/03/16

写真a

 
TAKEUCHI Kazuhito
 
Organization
Nagoya University Nagoya University Hospital Neurosurgery Lecturer of hospital
Title
Lecturer of hospital

Degree 1

  1. 博士(医) ( 名古屋大学 ) 

Research Areas 1

  1. Others / Others  / 神経内視鏡外科

Professional Memberships 4

  1. 日本頭蓋底外科学会

  2. 日本間脳下垂体腫瘍学会

  3. 日本神経内視鏡学会

  4. 日本脳神経外科学会

 

Papers 16

  1. Novel Endoscopic Technique for Inserting a Sheath into a Slit Ventricle: The Water-Slide Technique

    Yamamoto Taiki, Takeuchi Kazuhito, Nagata Yuichi, Mizuno Akihiro, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 145   page: 1 - 4   2021.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2020.08.206

    Web of Science

  2. Fully Endoscopic Transcylinder Trans-Magendie Foraminal Approach for Fourth Ventricular Cavernoma: A Technical Case Report

    Nagata Yuichi, Takeuchi Kazuhito, Yamamoto Taiki, Mizuno Akihiro, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 142   page: 104 - 107   2020.10

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2020.06.171

    Web of Science

  3. Endoscopic Treatment Strategy for a Disproportionately Large Communicating Fourth Ventricle: Case Series and Literature Review

    Kawabata Teppei, Takeuchi Kazuhito, Nagata Yuichi, Ishikawa Takayuki, Choo Jungsu, Wakabayashi Toshihiko

    NEUROLOGIA MEDICO-CHIRURGICA   Vol. 60 ( 7 ) page: 351 - 359   2020.7

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.2176/nmc.oa.2019-0299

    Web of Science

  4. Steroid-responsive recurrent tumefactive demyelination with multiple petechial hemorrhages along non-displaced medullary veins

    Tsuboi Takashi, Harada Yumiko, Suzuki Masashi, Ando Takashi, Atsuta Naoki, Ohka Fumiharu, Takeuchi Kazuhito, Taoka Toshiaki, Ohba Shigeo, Nakaguro Masato, Abe Masato, Nakashima Ichiro, Yoshida Mari, Katsuno Masahisa

    CLINICAL NEUROLOGY AND NEUROSURGERY   Vol. 193   2020.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.clineuro.2020.105764

    Web of Science

  5. H3F3A mutant allele specific imbalance in an aggressive subtype of diffuse midline glioma, H3 K27M-mutant

    Maeda Sachi, Ohka Fumiharu, Okuno Yusuke, Aoki Kosuke, Motomura Kazuya, Takeuchi Kazuhito, Kusakari Hironao, Yanagisawa Nobuyuki, Sato Shinya, Yamaguchi Junya, Tanahashi Kuniaki, Hirano Masaki, Kato Akira, Shimizu Hiroyuki, Kitano Yotaro, Yamazaki Shintaro, Yamashita Shinji, Takeshima Hideo, Shinjo Keiko, Kondo Yutaka, Wakabayashi Toshihiko, Natsume Atsushi

    ACTA NEUROPATHOLOGICA COMMUNICATIONS   Vol. 8 ( 1 )   2020.2

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40478-020-0882-4

    Web of Science

  6. Preservation of Olfactory Function Following Endoscopic Single-Nostril Transseptal Transsphenoidal Surgery

    Kawabata Teppei, Takeuchi Kazuhito, Nagata Yuichi, Ishikawa Takayuki, Choo Jungsu, Sato Yusuke, Tambara Masao, Teranishi Masaaki, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 132   page: E665 - E669   2019.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2019.08.051

    Web of Science

  7. Three types of dural suturing for closure of CSF leak after endoscopic transsphenoidal surgery

    Ishikawa Takayuki, Takeuchi Kazuhito, Nagata Yuichi, Choo Jungsu, Kawabata Teppei, Ishizaki Tomotaka, Wakabayashi Toshihiko

    JOURNAL OF NEUROSURGERY   Vol. 131 ( 5 ) page: 1625 - 1631   2019.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3171/2018.4.JNS18366

    Web of Science

    PubMed

  8. Peel-off resection of the pituitary gland for functional pituitary adenomas: pathological significance and impact on pituitary function

    Nagata Yuichi, Takeuchi Kazuhito, Yamamoto Taiki, Ishikawa Takayuki, Kawabata Teppei, Shimoyama Yoshie, Inoshita Naoko, Wakabayashi Toshihiko

    PITUITARY   Vol. 22 ( 5 ) page: 507 - 513   2019.10

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11102-019-00980-w

    Web of Science

  9. Endoscopic clipping of intraventricular aneurysms using the "wet-field" technique.

    Takeuchi K, Handa T, Chu J, Wada K, Wakabayashi T

    Journal of neurosurgery   Vol. 131 ( 1 ) page: 104 - 108   2019.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3171/2018.1.JNS172393

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    PubMed

  10. Removal of the Medial Wall of the Cavernous Sinus for Functional Pituitary Adenomas: A Technical Report and Pathologic Significance

    Nagata Yuichi, Takeuchi Kazuhito, Yamamoto Taiki, Ishikawa Takayuki, Kawabata Teppei, Shimoyama Yoshie, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 126   page: 53 - 58   2019.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2019.02.134

    Web of Science

  11. Quality of Life Changes Before and After Transsphenoidal Surgery for Sellar and Faros llar Lesions

    Ishikawa Takayuki, Takeuchi Kazuhito, Nagatani Tetsuya, Aimi Yuri, Tanemura Eriko, Tambara Masao, Nagata Yuichi, Choo Jungsu, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 122   page: E1202-E1210   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7076/j.wneu.2018.71.017

    Web of Science

  12. Quality of Life Changes Before and After Transsphenoidal Surgery for Sellar and Parasellar Lesions.

    Ishikawa T, Takeuchi K, Nagatani T, Aimi Y, Tanemura E, Tambara M, Nagata Y, Choo J, Wakabayashi T

    World neurosurgery   Vol. 122   page: e1202-e1210   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2018.11.017

    PubMed

  13. Neuroendoscopic Cylinder Surgery and 5-Aminolevulinic Acid Photodynamic Diagnosis of Deep-Seated Intracranial Lesions

    Choo Jungsu, Takeuchi Kazuhito, Nagata Yuichi, Ohka Fumiharu, Kishida Yugo, Watanabe Tadashi, Satoh Yusuke, Nagatani Tetsuya, Kato Kyozo, Wakabayashi Toshihiko, Natsume Atsushi

    WORLD NEUROSURGERY   Vol. 116   page: E35 - E41   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2018.03.112

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    PubMed

  14. Long-standing overt ventriculomegaly without aqueductal stenosis: A case report

    Ikumi Kazuhiro, Tsuboi Takashi, Atsuta Naoki, Takeuchi Kazuhito, Koike Haruki, Katsuno Masahisa

    NEUROLOGY AND CLINICAL NEUROSCIENCE   Vol. 6 ( 2 ) page: 42-44   2018.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ncn3.12176

    Web of Science

  15. Fully endoscopic combined transsphenoidal and supraorbital keyhole approach for parasellar lesions

    Nagata Yuichi, Watanabe Tadashi, Nagatani Tetsuya, Takeuchi Kazuhito, Chu Jonsu, Wakabayashi Toshihiko

    JOURNAL OF NEUROSURGERY   Vol. 128 ( 3 ) page: 685 - 694   2018.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3171/2016.11.JNS161833

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  16. A Novel Dissection Method Using a Flexible Neuroendoscope for Resection of Tumors Around the Aqueduct of Sylvius

    Ishikawa Takayuki, Takeuchi Kazuhito, Tsukamoto Nobuhiro, Kawabata Teppei, Wakabayashi Toshihiko

    WORLD NEUROSURGERY   Vol. 110   page: 391 - 396   2018.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.wneu.2017.11.044

    Web of Science

    PubMed

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. 脳室上衣繊毛ダイニン異常による非閉塞性水頭症の発症、増悪機序の分子学的解明

    Grant number:20K17959  2020.4 - 2023.3

    若手研究

    竹内 和人

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    Authorship:Principal investigator 

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    非閉塞性水頭症発症の一因として、脳室上衣の繊毛運動の機能不全による髄液還流障害が考えられている。Dpcd遺伝子異常により、脳室上衣繊毛内分子群の発現異常、構造変化が引き起こされる。Dpcdノックアウトマウスの運動繊毛ダイニンのトランスクリプトーム・プロテオーム解析を行い、非閉塞性水頭症に寄与する分子メカニズムの解明を目指す。また、Dpcdノックアウトマウスでは水頭症は経時的に増悪することも確認されている。繊毛運動障害による異常な髄液流が二次的に繊毛極性異常を引き起こすと考えられる。このメカニズムを、脳室間での違いや経時的な変化から解析し、非閉塞性水頭症の発生及び増悪の原因究明につなげる。

  2. Abnormal cerebrospinal fluid dynamics due to ciliary movement disorder and molecular biological analysis of dynein

    Grant number:17K17792  2017.4 - 2020.3

    Takeuchi Kazuhito

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    Authorship:Principal investigator 

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    Using a hydrocephalic model mouse (Dpcd knockout mouse: Dpcd KO mouse) showing abnormal ciliary movement, the expression pattern and mechanism of hydrocephalus were investigated. This hydrocephalus showed lateral ventricle and third ventricle enlargement, but no fourth ventricle enlargement, suggesting that there is a phenotypic difference between the ventricles. Among the eight molecular species that compose the mouse inner arm dynein, it was revealed that the mRNA expression of Dnah1 was decreased and that of Dnah6 was increased. In addition, partial loss of the inner arm dynein was confirmed by structural analysis using a transmission electron microscope. It was clarified that the knockout of Dpcd gene resulted in gene polymorphism and structural abnormality of multiple dynein molecular species.