Updated on 2024/03/15

写真a

 
UCHIDA Hiroo
 
Organization
Institutes of Innovation for Future Society Professor
Graduate School of Medicine Professor
Graduate School
Graduate School of Medicine
Title
Professor
Contact information
メールアドレス
External link

Degree 1

  1. 博士(医学) ( 2001.3   東京大学 ) 

Research Interests 8

  1. pediatric cancer

  2. minimally invasive surgery

  3. medical instrument

  4. pediatric surgery

  5. pediatric surgery

  6. minimally invasive surgery

  7. medical instrument

  8. pediatric cancer

Research Areas 1

  1. Life Science / General surgery and pediatric surgery

Current Research Project and SDGs 3

  1. 胆道閉鎖症の原因解明

  2. 低侵襲手術

  3. pediatric oncology

Research History 18

  1. Nagoya University   Nagoya University Hospital Children's Cancer Center

    2016.4

  2. Nagoya University   Nagoya University Hospital Children's Cancer Center

    2016.4

  3. 名古屋大学大学院医学系研究科 小児外科学 教授

    2013.8

      More details

    Country:Japan

  4. Nagoya University   Graduate School of Medicine

    2013.8

  5. Nagoya University   Graduate School of Medicine Program in Integrated Medicine Musculoskeletal and Cutaneous Medicine   Professor

    2013.8

  6. 埼玉県立小児医療センター 小児外科 科長

    2009.2 - 2013.7

      More details

    Country:Japan

  7. 埼玉県立小児医療センター 小児外科 科長

    2009.2 - 2013.7

  8. 埼玉県立小児医療センター 小児外科 副部長

    2006.4 - 2009.1

      More details

    Country:Japan

  9. 埼玉県立小児医療センター 小児外科 副部長

    2006.4 - 2009.1

  10. 埼玉県立小児医療センター 小児外科 医長

    2003.4 - 2006.3

      More details

    Country:Japan

  11. 埼玉県立小児医療センター 小児外科 医長

    2003.4 - 2006.3

  12. 獨協医科大学越谷病院 小児外科講師

    2001.4 - 2003.3

      More details

    Country:Japan

  13. Dokkyo Medical University   Koshigaya Hospital

    2001.4 - 2003.3

  14. 自治医科大学一般外科・小児外科助手

    1995.7 - 1997.3

      More details

    Country:Japan

  15. 自治医科大学一般外科・小児外科医員

    1994.4 - 1995.6

      More details

    Country:Japan

  16. 東京大学医学部附属病院小児外科医員

    1993.6 - 1994.3

      More details

    Country:Japan

  17. 財団法人竹田綜合病院 外科医員

    1990.12 - 1993.5

      More details

    Country:Japan

  18. 東京大学医学部附属病院第2外科系研修医

    1989.6 - 1990.11

      More details

    Country:Japan

▼display all

Education 4

  1. The University of Tokyo   Graduate School, Division of Medical Sciences

    1997.4 - 2001.3

      More details

    Country: Japan

  2. The University of Tokyo   Graduate School, Division of Medical Sciences

    1997.4 - 2001.3

      More details

    Country: Japan

  3. The University of Tokyo   Graduate School, Division of Medical Sciences

    1997.4 - 2001.3

      More details

    Country: Japan

  4. The University of Tokyo   Faculty of Medicine

    1983.4 - 1989.3

      More details

    Country: Japan

Professional Memberships 18

  1. 日本内視鏡外科学会   理事

    2020.12

  2. 日本小児外科学会   理事

    2021.6

  3. 日本外科学会   代議員

    2014.2

  4. 日本内視鏡外科学会

  5. 日本小児外科学会   評議員

    2009.4

  6. International Pediatric Endosurgery Group

  7. The Pacific Association of Pediatric Surgeons

  8. 日本小児血液・がん学会

  9. 日本小児泌尿器科学会

  10. 日本臨床外科学会

  11. International Pediatric Endosurgery Group

  12. 日本臨床外科学会

  13. 日本小児血液・がん学会

  14. 日本小児泌尿器科学会

  15. 日本小児外科学会

  16. 日本外科学会

  17. 日本内視鏡外科学会

  18. The Pacific Association of Pediatric Surgeons

▼display all

 

Papers 432

  1. Multicenter, retrospective, comparative study of laparoscopic and open Kasai portoenterostomy in children with biliary atresia from Japanese high-volume centers Reviewed

    Murase Naruhiko, Hinoki Akinari, Shirota Chiyoe, Tomita Hirofumi, Shimojima Naoki, Sasaki Hideyuki, Nio Masaki, Tahara Kazunori, Kanamori Yutaka, Shinkai Masato, Yamamoto Hirotoshi, Sugawara Yasuhiko, Hibi Taizo, Ishimaru Tetsuya, Kawashima Hiroshi, Koga Hiroyuki, Yamataka Atsuyuki, Uchida Hiroo

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 26 ( 1 ) page: 43 - 50   2019.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jhbp.594

    Web of Science

    PubMed

  2. Surgical Strategies for Neonates with Prenatally Diagnosed Congenital Biliary Dilatation. Reviewed

    Shirota C, Hinoki A, Tainaka T, Sumida W, Makita S, Amano H, Takimoto A, Yasui A, Nakagawa Y, Liu J, Guo Y, Kato D, Goda Y, Maeda T, Uchida H

    Journal of pediatric surgery   Vol. 59 ( 3 ) page: 385 - 388   2024.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2023.10.045

    PubMed

  3. Scoring system for diagnosis and pretreatment risk assessment of neuroblastoma using urinary biomarker combinations. Reviewed International journal

    Hizuru Amano, Hiroo Uchida, Kazuharu Harada, Atsushi Narita, Shigehisa Fumino, Yuji Yamada, Shun Kumano, Mayumi Abe, Takashi Ishigaki, Minoru Sakairi, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Shuhei Karakawa, Yuichi Mitani, Shojiro Matsumoto, Yutaka Tomioka, Hideki Muramatsu, Nobuhiro Nishio, Tsuyoshi Osawa, Masataka Taguri, Katsuyoshi Koh, Tatsuro Tajiri, Motohiro Kato, Kimikazu Matsumoto, Yoshiyuki Takahashi, Akinari Hinoki

    Cancer science     2024.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    The urinary catecholamine metabolites, homovanillic acid (HVA) and vanillylmandelic acid (VMA), are used for the adjunctive diagnosis of neuroblastomas. We aimed to develop a scoring system for the diagnosis and pretreatment risk assessment of neuroblastoma, incorporating age and other urinary catecholamine metabolite combinations. Urine samples from 227 controls (227 samples) and 68 patients with neuroblastoma (228 samples) were evaluated. First, the catecholamine metabolites vanillactic acid (VLA) and 3-methoxytyramine sulfate (MTS) were identified as urinary marker candidates through comprehensive analysis using liquid chromatography-mass spectrometry. The concentrations of these marker candidates and conventional markers were then compared among controls, patients, and numerous risk groups to develop a scoring system. Participants were classified into four groups: control, low risk, intermediate risk, and high risk, and the proportional odds model was fitted using the L2-penalized maximum likelihood method, incorporating age on a monthly scale for adjustment. This scoring model using the novel urine catecholamine metabolite combinations, VLA and MTS, had greater area under the curve values than the model using HVA and VMA for diagnosis (0.978 vs. 0.964), pretreatment risk assessment (low and intermediate risk vs. high risk: 0.866 vs. 0.724; low risk vs. intermediate and high risk: 0.871 vs. 0.680), and prognostic factors (MYCN status: 0.741 vs. 0.369, histology: 0.932 vs. 0.747). The new system also had greater accuracy in detecting missing high-risk neuroblastomas, and in predicting the pretreatment risk at the time of screening. The new scoring system employing VLA and MTS has the potential to replace the conventional adjunctive diagnostic method using HVA and VMA.

    DOI: 10.1111/cas.16116

    PubMed

  4. 特集 胆道閉鎖症の研究update 胆道閉鎖症診療ガイドラインの改訂に向けて Reviewed

    仁尾 正記, 虻川 大樹, 内田 広夫, 黒田 達夫, 鈴木 達也, 山髙 篤行, 吉田 雅博, 和田 基, 佐々木 英之, 大久保 龍二

    小児外科   Vol. 56 ( 2 ) page: 170 - 173   2024.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000726

    CiNii Research

  5. Laparoscopic Fundoplication in Patients with Ventriculoperitoneal Shunts: A Systematic Review and Our Experience Reviewed

    Kato, D; Uchida, H; Tainaka, T; Amano, H; Ono, Y; Yasui, A; Shirota, C; Sumida, W; Yokota, K; Makita, S; Takimoto, A; Takada, S; Nakagawa, Y; Gohda, Y; Maeda, T; Hinoki, A

    JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES   Vol. 34 ( 3 ) page: 268 - 273   2024.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2023.0220

    Web of Science

    PubMed

  6. M U-Net: Intestine Segmentation Using Multi-dimensional Features for Ileus Diagnosis Assistance Reviewed

    Qin An, Hirohisa Oda, Yuichiro Hayashi, Takayuki Kitasaka, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Aitaro Takimoto, Masahiro Oda, Kensaku Mori

    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)   Vol. 14313   page: 135 - 144   2024

     More details

    Language:English   Publishing type:Research paper (international conference proceedings)  

    The intestine is an essential digestive organ that can cause serious health problems once diseased. This paper proposes a method for intestine segmentation to intestine obstruction diagnosis assistance called multi-dimensional U-Net (M U-Net). We employ two encoders to extract features from two-dimensional (2D) CT slices and three-dimensional (3D) CT patches. These two encoders collaborate to enhance the segmentation accuracy of the model. Additionally, we incorporate deep supervision with the M U-Net to reduce the limitation of training with sparse label data sets. The experimental results demonstrated that the Dice of the proposed method was 73.22%, the recall was 79.89%, and the precision was 70.61%.

    DOI: 10.1007/978-3-031-47076-9_14

    Web of Science

    Scopus

  7. Anastomotic time was associated with postoperative complications: a cumulative sum analysis of thoracoscopic repair of tracheoesophageal fistula in a single surgeon's experience. Reviewed

    Yaohui Guo, Akinari Hinoki, Kyoichi Deie, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Masamune Okamoto, Aitarou Takimoto, Akihiro Yasui, Shunya Takada, Yoichi Nakagawa, Daiki Kato, Takuya Maeda, Hizuru Amano, Hiroshi Kawashima, Hiroo Uchida, Chiyoe Shirota

    Surgery today   Vol. 53 ( 12 ) page: 1363 - 1371   2023.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: This study aimed to evaluate the learning curve of thoracoscopic repair of tracheoesophageal fistula (TEF) by a single surgeon using a cumulative sum (CUSUM) analysis. METHODS: Prospective clinical data of consecutive Gross type-C TEF repairs performed by a pediatric surgeon from 2010 to 2020 were recorded. CUSUM charts for anastomosis and operating times were generated. The learning curves were compared with the effect of accumulation based on case experience. RESULTS: For 33 consecutive cases, the mean operative and anastomosis times were 139 ± 39 min and 3137 ± 1110 s, respectively. Significant transitions beyond the learning phase for total operating and anastomosis times were observed at cases 13 and 17. Both the total operating time and anastomosis time were significantly faster in the proficiency improvement phase than in the initial learning phase. Postoperative complications significantly decreased after the initial anastomosis learning phase but not after the initial total operating learning phase. CONCLUSIONS: Thoracoscopic repair of TEF is considered safe and feasible after 13 cases, where the surgeon can improve their proficiency with the total operation procedure, and 17 cases, which will enable the surgeon to achieve proficiency in anastomosis. Postoperative complications significantly decreased after gaining familiarity with the anastomosis procedure through the learning phase.

    DOI: 10.1007/s00595-023-02687-9

    Web of Science

    PubMed

  8. Preoperative management comprising tube irrigation using a trans-anal indwelling tube for infants with hirschsprung disease can allow single-stage radical surgery. Reviewed International journal

    Nakagawa Y, Uchida H, Hinoki A, Tainaka T, Shirota C, Sumida W, Makita S, Yokota K, Amano H, Yasui A, Maeda T, Kato D, Gohda Y

    BMC SURGERY   Vol. 23 ( 1 ) page: 333   2023.11

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12893-023-02232-y

    PubMed

  9. Variations of the hepatic artery and bile duct in patients with pancreaticobiliary maljunction: Impact on postoperative outcomes Reviewed

    Takada, S; Uchida, H; Hinoki, A; Shirota, C; Sumida, W; Tainaka, T; Makita, S; Takimoto, A; Nakagawa, Y; Maeda, T

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 30 ( 11 ) page: 1241 - 1248   2023.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jhbp.1381

    Web of Science

    PubMed

  10. A new criterion including the aspartate aminotransferase-to-platelet ratio index and liver and spleen stiffness to rule out varices needing treatment in children with biliary atresia: Modification of the Baveno VII criteria. Reviewed International journal

    Shinya Yokoyama, Yoji Ishizu, Takashi Honda, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Hisanori Muto, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Shunya Takada, Yoichi Nakagawa, Takuya Maeda, Masanao Nakamura, Masatoshi Ishigami, Hiroo Uchida, Hiroki Kawashima

    Hepatology research : the official journal of the Japan Society of Hepatology     2023.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    AIMS: Biliary atresia (BA) is a congestive biliary disease that develops in the neonatal period or early infancy. It may present with portal hypertension and varices needing treatment (VNT) even after successful Kasai portoenterostomy. This study aimed to stratify the risk of VNT in children and adolescents with BA. METHODS: In this prospective cross-sectional study, we measured liver stiffness (LS) and spleen stiffness (SS) by two-dimensional shear wave elastography and checked for VNT endoscopically in 53 patients with BA who attended for follow-up between July 2018 and September 2022. Varices needing treatment were defined as large esophageal varices, esophageal varices of any size with red color signs, and/or gastric varices along the cardia. RESULTS: Twenty-five patients (aged 0-18 years) had VNT. Eighteen patients met the Baveno VI criteria (LS <20 kPa; platelet count >150 000/L) and were deemed to be at low risk of VNT (spared endoscopies) while three had missed VNT (16.7%). Applying the Baveno VII criteria, which combines the SS cut-off value of 40 kPa with the Baveno VI criteria, resulted in five missed VNTs among 22 spared endoscopies (22.7%). A modification of the Baveno VII criteria using the aspartate aminotransferase-to-platelet ratio index (APRI) instead of the platelet count with cut-off values of 25 kPa, 30 kPa, and 1.04 for LS, SS, and APRI, respectively, missed only one VNT (5.0%) among 20 spared endoscopies. CONCLUSIONS: A novel diagnostic criterion that combines LS, SS, and APRI reduced the risk of missing VNT to 5% in children and adolescents with BA.

    DOI: 10.1111/hepr.13976

    PubMed

  11. Safe thoracoscopic repair of recurrent congenital diaphragmatic hernia after initial open abdominal repair Reviewed

    Gohda, Y; Yokota, K; Uchida, H; Shirota, C; Tainaka, T; Sumida, W; Makita, S; Takimoto, A; Takada, S; Nakagawa, Y; Maeda, T; Guo, YH; Hinoki, A

    SURGERY TODAY     2023.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-023-02757-y

    Web of Science

    PubMed

  12. Refractory esophageal anastomotic stricture after esophageal atresia surgery improved with retrograde balloon dilatation through gastrostomy followed by laparoscopic fundoplication: a case report Reviewed

    Nakagawa, Y; Uchida, H; Hinoki, A; Shirota, C; Sumida, W; Makita, S; Yokota, K; Amano, H; Yasui, A; Kato, D; Gohda, Y; Maeda, T

    SURGICAL CASE REPORTS   Vol. 9 ( 1 ) page: 169   2023.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40792-023-01754-0

    Web of Science

    PubMed

  13. How many cases do instructor class pediatric surgeons need to experience to be an independent operator in performing advanced endoscopic surgery? A nationwide survey to establish an ideal curriculum for pediatric endoscopic surgery in Japan Reviewed

    Murakami, M; Onishi, S; Yamada, K; Ogawa, K; Yokoyama, S; Kurashima, Y; Miyano, G; Ishimaru, T; Kawashima, H; Uchida, H; Yamataka, A; Okuyama, H; Ieiri, S

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 39 ( 1 ) page: 271   2023.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-023-05550-7

    Web of Science

    PubMed

  14. Robotic versus laparoscopic radical surgery for pediatric congenital biliary dilatation: a comparison of surgical outcomes of a single surgeon's initial experience Reviewed

    Maeda, T; Liu, JH; Uchida, H; Amano, H; Shirota, C; Tainaka, T; Sumida, W; Makita, S; Takimoto, A; Takada, S; Nakagawa, Y; Gouda, A; Guo, YH; Hinoki, A

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 39 ( 1 ) page: 261   2023.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-023-05548-1

    Web of Science

    PubMed

  15. Management of congenital and postoperative chylothorax: Use of thoracoscopic lymphatic leak ligations with intraoperative ICG lymphangiography. Reviewed International journal

    Shunya Takada, Chiyoe Shirota, Hiroo Uchida, Hizuru Amano, Akinari Hinoki, Wataru Sumida, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Youichi Nakagawa, Daiki Kato, Yaohui Guo, Takahisa Tainaka

    Journal of pediatric surgery   Vol. 58 ( 9 ) page: 1754 - 1761   2023.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Congenital chylothorax (CCT) and postoperative chylothorax (POCT) are rare and difficult to treat. We report our treatment strategy and outcomes for chylothorax, including thoracoscopic surgery with indocyanine-green (ICG) near-infrared fluorescence lymphangiography. METHODS: A retrospective review of patients with CCT and POCT from 2014 to 2021 was performed. After definitive diagnosis, conservative treatments with octreotide, followed by intravenous steroids as needed, were performed. Patients who were refractory to conservative treatment were transferred to surgical treatment, consisting of thoracoscopic lymphatic leak ligations using ICG intraoperative lymphangiography. The effectiveness of conservative and surgical treatment was then examined. RESULTS: We included 19 cases of CCT and 31 cases of POCT. The 31 POCT patients included 23 of 84 postoperative patients with congenital diaphragmatic hernia (CDH), 7 of 54 postoperative patients with esophageal atresia (EA), and 1 of 3 postoperative patients with lymphatic malformation. The efficacy of conservative treatment was 12/19 for CCT, 22/23 for CDH, and 4/7 for EA. Surgical intervention was performed in 10 patients, and the rate of resolution of chylothorax within 3 weeks after surgery was 90%. CONCLUSION: Thoracoscopic lymphatic leak ligations with intraoperative ICG lymphangiography are feasible and useful in patients with chylothorax refractory to conservative treatment. LEVEL OF EVIDENCE: Level IV.

    DOI: 10.1016/j.jpedsurg.2022.11.018

    Web of Science

    PubMed

  16. Comprehension of fundamental knowledge about pediatric endoscopic surgery: a cross-sectional study in Japan Reviewed

    Yokoyama, S; Kurashima, Y; Ieiri, S; Yamataka, A; Okuyama, H; Uchida, H; Ishimaru, T; Hirano, S

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 37 ( 8 ) page: 6408 - 6416   2023.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00464-023-09975-y

    Web of Science

    PubMed

  17. IgG4-related disease of duodenal obstruction due to multiple ulcers in a 12-year-old girl Reviewed

    BMC PEDIATRICS   Vol. 23 ( 1 ) page: 376   2023.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12887-023-04190-z

    Web of Science

    PubMed

  18. 特集 急性虫垂炎:診断,治療,研究 複雑性虫垂炎の緊急手術 Reviewed

    田井中 貴久, 城田 千代栄, 住田 亙, 横田 一樹, 牧田 智, 岡本 眞宗, 小梛 地洋, 長島 俊介, 檜 顕成, 内田 広夫

    小児外科   Vol. 55 ( 7 ) page: 751 - 754   2023.7

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000514

    CiNii Research

  19. Case report: Laparoscopic gastrojejunostomy for duodenal atresia with situs inversus and preduodenal portal vein: a report of two cases Reviewed

    Nakagawa, Y; Sumida, W; Makita, S; Uchida, H; Hinoki, A; Shirota, C; Tainaka, T; Yokota, K; Amano, H; Yasui, A; Takimoto, A; Kato, D; Maeda, T; Gohda, Y

    FRONTIERS IN PEDIATRICS   Vol. 11   page: 1220393   2023.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fped.2023.1220393

    Web of Science

    PubMed

  20. Case Report: Retropancreatic fascia hernia protruding into the thoracic cavity through a Bochdalek hernia Reviewed

    Nakagawa, Y; Maeda, T; Uchida, H; Takada, S; Hinoki, A; Shirota, C; Tainaka, T; Sumida, W; Makita, S; Amano, H; Takimoto, A; Gohda, Y

    FRONTIERS IN PEDIATRICS   Vol. 11   page: 1149515   2023.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fped.2023.1149515

    Web of Science

    PubMed

  21. Preoperative Contrast Examinations Help Determine the Appropriate Cervical Approach for Congenital Gross Type C Esophageal Atresia: A Report of Two Cases Reviewed

    Nakagawa, Y; Uchida, H; Shirota, C; Tainaka, T; Sumida, W; Amano, H; Takimoto, A; Ogata, S; Takada, S; Maeda, T; Gohda, Y; Guo, YH; Hinoki, A

    AMERICAN JOURNAL OF CASE REPORTS   Vol. 24   page: e938723   2023.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.12659/AJCR.938723

    Web of Science

    PubMed

  22. 特集 ロボット支援手術 ロボット支援下胆管切除術 Reviewed

    牧田 智, 内田 広夫, 住田 亙, 檜 顕成, 城田 千代栄, 田井中 貴久, 天野 日出, 滝本 愛太朗, 高田 瞬也, 中川 洋一, 合田 陽祐, 前田 拓也, 郭 垚輝, 劉 佳慧

    小児外科   Vol. 55 ( 5 ) page: 544 - 551   2023.5

     More details

    Authorship:Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000451

    CiNii Research

  23. 特集 ロボット支援手術 小児外科領域におけるプロクター制度 Invited

    内田 広夫

    小児外科   Vol. 55 ( 5 ) page: 497 - 501   2023.5

     More details

    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000439

    CiNii Research

  24. Hemi-circumferential mucosal resection and anastomosis procedure for rectal prolapse following anorectoplasty for anorectal malformations. Reviewed

    Aitaro Takimoto, Hizuru Amano, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Masamune Okamoto, Seiya Ogata, Shunya Takada, Yoichi Nakagawa, Daiki Kato, Yosuke Gohda, Akinari Hinoki, Hiroo Uchida

    Surgery today   Vol. 53 ( 5 ) page: 628 - 632   2023.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Rectal prolapse after radical surgery for anorectal malformations (ARMs) is a common postoperative complication that causes bleeding and stenosis, and sometimes requires surgical treatment. Different surgical techniques have been reported, but most are associated with high recurrence rates and a long postoperative stay. We performed the hemi-circumferential mucosal resection and anastomosis procedure (HCMR) to preserve anal muscle and anal function. Here, we report the success of our minimally invasive surgical approach to correct rectal prolapse in patients with ARMs. METHODS: The subjects of this retrospective review were patients who underwent HCMR for rectal prolapse after radical surgery for ARMs between January, 2014 and August, 2021. HCMR involves rectal mucosal resection without muscle plication. RESULTS: A collective 15 HCMR procedures were performed in 10 patients. The median age at repair was 1.8 years (range, 10 months-18 years). The median operation time and postoperative length of stay were 46 min (range, 17-85 min) and 3 days (range, 1-7 days), respectively. The median postoperative observation period was 3 years 4 months (range, 8 months-7 years 10 months) and no complications or recurrences were observed. CONCLUSIONS: HCMR is a safe and effective surgical treatment for rectal prolapse after radical operation for ARMs, which is minimally invasive and preserves rectal muscle and function.

    DOI: 10.1007/s00595-022-02611-7

    Web of Science

    PubMed

  25. Single-cell RNA sequencing of intestinal immune cells in neonatal necrotizing enterocolitis. Reviewed International journal

    Kazuo Oshima, Akinari Hinoki, Hiroo Uchida, Yujiro Tanaka, Yusuke Okuno, Yasuhiro Go, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Aitaro Takimoto, Yoko Kano, Shinichiro Sawa

    Pediatric surgery international   Vol. 39 ( 1 ) page: 179 - 179   2023.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Necrotizing enterocolitis (NEC) causes fatal intestinal necrosis in neonates, but its etiology is unknown. We analyzed the intestinal immune response to NEC. METHODS: Using single-cell RNA sequencing (scRNA-seq), we analyzed the gene expression profiles of intestinal immune cells from four neonates with intestinal perforation (two with NEC and two without NEC). Target mononuclear cells were extracted from the lamina propria of the resected intestines. RESULTS: In all four cases, major immune cells, such as T cells (15.1-47.7%), B cells (3.1-19.0%), monocytes (16.5-31.2%), macrophages (1.6-17.4%), dendritic cells (2.4-12.2%), and natural killer cells (7.5-12.8%), were present in similar proportions to those in the neonatal cord blood. Gene set enrichment analysis showed that the MTOR, TNF-α, and MYC signaling pathways were enriched in T cells of the NEC patients, suggesting upregulated immune responses related to inflammation and cell proliferation. In addition, all four cases exhibited a bias toward cell-mediated inflammation, based on the predominance of T helper 1 cells. CONCLUSION: Intestinal immunity in NEC subjects exhibited stronger inflammatory responses compared to non-NEC subjects. Further scRNA-seq and cellular analysis may improve our understanding of the pathogenesis of NEC.

    DOI: 10.1007/s00383-023-05461-7

    Web of Science

    PubMed

  26. Rare case of a right Bochdalek hernia with retroperitoneal prolapse of organs into the thoracic cavity in infancy: A case report. Reviewed

    Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Hizuru Amano, Okamoto Masamune, Aitaro Takimoto, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda, Yaohui Guo

    Asian journal of endoscopic surgery   Vol. 16 ( 2 ) page: 284 - 288   2023.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    We report an extremely rare case of a right Bochdalek hernia with a sac, in which the retroperitoneal and intra-abdominal organs prolapsed into the thoracic cavity at the same time. The patient was a 7-month-old female with no comorbidities. She presented with cough and fever, and chest radiography revealed a right diaphragmatic hernia. Computed tomography showed that the right kidney, intestine, colon, and liver had prolapsed into the thoracic cavity. The patient underwent thoracoscopic surgery, which showed that the abdominal and retroperitoneal organs prolapsed into the thoracic cavity through the Bochdalek hernia. The herniated organs were spontaneously reduced using thoracoscopic insufflation. The defect hole was closed with artificial mesh. We adopted a thoracoscopic approach, in terms of easy reduction of herniated organs and accurate evaluation of the hernia orifice, which was useful.

    DOI: 10.1111/ases.13139

    Web of Science

    PubMed

  27. Editorial: Infants with cholestasis Reviewed

    Uchida, H; Tiao, GM; Shivakumar, P; Wong, KKY; Asai, A; Amano, H

    FRONTIERS IN PEDIATRICS   Vol. 11   page: 1175231   2023.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fped.2023.1175231

    Web of Science

    PubMed

  28. Update on aortopexy and posterior tracheopexy for tracheomalacia in patients with esophageal atresia Reviewed

    Sumida, W; Yasui, A; Shirota, C; Makita, S; Okamoto, M; Ogata, S; Takimoto, A; Takada, S; Nakagawa, Y; Kato, D; Gohda, Y; Amano, H; Guo, YH; Hinoki, A; Uchida, H

    SURGERY TODAY   Vol. 54 ( 3 ) page: 211 - 219   2023.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-023-02652-6

    Web of Science

    PubMed

  29. A new type of retropancreatic fascia hernia in the supramesocolic space preoperatively misdiagnosed as a diaphragmatic hernia: report of two cases. Reviewed International journal

    Yoichi Nakagawa, Hiroo Uchida, Satoshi Makita, Kazuki Yokota, Akinari Hinoki, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Hizuru Amano, Seiya Ogata, Aitaro Takimoto, Shunya Takada, Takuya Maeda, Yousuke Gohda

    Surgical case reports   Vol. 9 ( 1 ) page: 5 - 5   2023.1

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: We encountered two cases of a new type of retroperitoneal hernia. We herein report the unique features of these cases. CASE PRESENTATION: Case 1: A Japanese girl was born at a gestational age of 37 weeks, weighing 2550 g. She underwent laparotomic left diaphragmatic hernia repair for a left Bochdalek hernia at the age of one day. The postoperative course was uneventful; however, chest radiography at the age of 35 days revealed bowel gas in the mediastinum, while computed tomography exhibited intestinal prolapses from the medial side of the mesh into the thoracic cavity. Reoperation was performed at the age of 77 days, showing that the defect hole was not at the diaphragm but in the absence of retropancreatic fascia, which was connected to the posterior mediastinum from the supramesocolic space. The mediastinum space was closed with a suturing spine and artificial mesh, and the defect hole in the pancreatic body was sutured. Case 2: A Japanese boy was born at a gestational age of 40 weeks, weighing 3502 g. He was diagnosed with a left diaphragmatic hernia at birth and underwent laparotomy at the age of two days. Operative findings showed no defect hole in the diaphragm, and no intestine was observed in the abdominal cavity. After close observation of the abdominal cavity, the intestine was found around the pancreatic body, and manual reduction of the intestine was performed. The defect hole existed in the absence of the retropancreatic fascia, which was connected to the extra-pleural space. The defect hole in the pancreatic body was sutured and closed with a non-absorbable thread. CONCLUSIONS: We assumed that our cases were a new type of retroperitoneal hernia, which we named "retropancreatic fascia hernia".

    DOI: 10.1186/s40792-023-01586-y

    PubMed

  30. Laparoscopic restorative proctocolectomy with ileal-J-pouch anal canal anastomosis without diverting ileostomy for total colonic and extensive aganglionosis is safe and feasible with combined Lugol's iodine staining technique and indocyanine green fluorescence angiography Reviewed

    Nakagawa, Y; Yokota, K; Uchida, H; Hinoki, A; Shirota, C; Tainaka, T; Sumida, W; Makita, S; Amano, H; Takimoto, A; Ogata, S; Takada, S; Maeda, T; Gohda, Y

    FRONTIERS IN PEDIATRICS   Vol. 10   page: 1090336   2023.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fped.2022.1090336

    Web of Science

    PubMed

  31. Laparoscopic closure of Roux limb perforation during double-balloon endoscopic retrograde cholangiography with laparoscopy-assisted endoscopic hepatolithectomy 30 years after congenital biliary dilatation radical surgery: A case report. Reviewed

    Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Okamoto Masamune, Seiya Ogata, Aitaro Takimoto, Shunya Takada, Daiki Kato, Yousuke Gohda

    Asian journal of endoscopic surgery   Vol. 16 ( 1 ) page: 118 - 122   2023.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    We report a case of hepatolithiasis 30 years after congenital biliary dilatation (CBD) surgery. A 31-year-old woman presented with fever and epigastric pain. She had a history of radical surgery for type I CBD at the age of 1 year and had no significant symptoms for approximately 30 years after surgery. Laboratory and imaging results showed hepatolithiasis at the common trunk of segments II and III with cholangitis. She was admitted to our hospital for antibiotics and underwent double-balloon endoscopic retrograde cholangiography (DBERC) to treat the hepatolithiasis. Roux-limb jejunum was perforated during DBERC; hence, emergent laparoscopic perforation site closure and simultaneous endoscopic lithotomy through the Roux-limb jejunum with exteriorization via umbilical incision were performed. The postoperative course was uneventful, and the patient was discharged without any complications.

    DOI: 10.1111/ases.13116

    Web of Science

    PubMed

  32. Retroperitoneoscopic resection of a large paraganglioma surrounded by the right diaphragmatic crus on the dorsal side of the inferior vena cava: A pediatric case report. Reviewed

    Aitaro Takimoto, Wataru Sumida, Chiyoe Shirota, Satoshi Makita, Masamune Okamoto, Seiya Ogata, Shunya Takada, Yoichi Nakagawa, Daiki Kato, Yosuke Goda, Akinari Hinoki, Hiroo Uchida

    Asian journal of endoscopic surgery   Vol. 16 ( 1 ) page: 131 - 134   2023.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Pheochromocytomas and paragangliomas are rare tumors. A 10 year-old girl was brought to the emergency room with complaints of sudden vomiting and convulsions, and was initially diagnosed with hypertensive encephalopathy. Magnetic resonance imaging and computed tomography scan showed a large mass (6 × 3 × 3 cm) on the dorsal side of the inferior vena cava, surrounded by the right diaphragmatic crus, and closely attached to the aorta. Blood noradrenaline, urinary normetanephrine, and noradrenaline levels were elevated. The final diagnosis was retroperitoneal paraganglioma, then, surgery was contemplated. The location of the liver and great vessels in front of the tumor made the commonly performed transabdominal approach complicated. Therefore, retroperitoneoscopic surgery was preferred for safer resection, with better visualization in a sufficient space with less risk of damaging the surrounding organs. The retroperitoneoscopic approach is a good indication for tumors located behind the great vessels.

    DOI: 10.1111/ases.13119

    PubMed

  33. The presence of high-risk varices after sclerotherapy in biliary atresia. Reviewed International journal

    Shinya Yokoyama, Yoji Ishizu, Takashi Honda, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Aitaro Takimoto, Yoichi Nakagawa, Shunya Takada, Masatoshi Ishigami, Hiroo Uchida, Hiroki Kawashima

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 65 ( 1 ) page: e15454   2023.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Esophagogastric varices (EGVs) may develop as a result of portal hypertension in children with biliary atresia (BA). Although endoscopic injection sclerotherapy (EIS) with ethanolamine oleate (EO) is reported useful for children, risk factors associated with the presence of high-risk EGVs after treatment remain unknown. METHODS: The subjects were BA patients under 15 years of age who underwent EO-EIS. We retrospectively reviewed a total of 28 treatment sessions of EGVs with red signs and those larger than F2, which were considered to be at high risk of bleeding. Survival analysis was performed for the presence of high-risk EGVs at the time of follow-up endoscopy as the occurrence of an event. RESULTS: Univariate analysis showed a significantly increased risk of the presence of high-risk EGVs post-EO-EIS in patients with increased liver stiffness (LS) and Mac-2 binding protein glycan isomer (M2BPGi), with hazard ratios of 1.48 and 1.15, respectively. The median presence-free period was significantly shorter in the LS ≥ 2.8 m/sec patients than in those with LS < 2.8 m/sec (189 vs. 266 days). Similarly, the median presence-free period was significantly shorter in patients with M2BPGi ≥ 4.0 than in those with M2BPGi < 4.0 (182 vs. 203 days). The results of multivariate analysis revealed that the risk of the presence of high-risk EGVs was significantly higher only in the high-LS group, with a hazard ratio of 2.76. CONCLUSIONS: Increased LS is associated with risk of the presence of high-risk EGVs following EO-EIS in children with BA. (246 words).

    DOI: 10.1111/ped.15454

    Web of Science

    PubMed

  34. 先天性十二指腸閉鎖症・狭窄症に合併した膵・胆管合流異常の4例 Reviewed

    牧田 智, 内田 広夫, 檜顕 成, 寺脇 幹, 城田 千代栄, 田井中 貴久, 住田 亙, 横田 一樹, 天野 日出, 滝本 愛太朗, 安井 昭洋, 中川 洋一, 加藤 大幾, 合田 陽祐, 前田 拓也, 郭 垚輝, 劉 佳慧

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 46 ( 0 ) page: 52 - 53   2023

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.46.0_52

    CiNii Research

  35. AI画像解析による内視鏡外科手術手技のビデオ評価及び手術支援システムの構築 Reviewed

    安井 昭洋, 内田 広夫, 森 健策, 石田 昇平, 出家 亨一, 檜 顕成, 城田 千代栄, 小田 昌宏, 林 雄一郎

    生体医工学   Vol. Annual61 ( Abstract ) page: 127_2 - 127_2   2023

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:公益社団法人 日本生体医工学会  

    <p>【はじめに】術後成長発達する小児患者にとって、低侵襲手術は非常に重要である。しかし患者数は限られているため、しっかりとした手術を行うためにoff the job-training(OJT)が重要である。さらにOJTでの効率的な手技獲得には、手技を客観的に評価しfeed backを行うシステムが必須である。また安全で効率的な内視鏡手術を行うためには、臓器の位置関係の把握が必要であるため、術中ナビゲーションは重要な要件となる。これらの課題に対して、AIを用いた内視鏡手技評価および手術支援システムの構築に着手しており現状の成果を報告する。【方法と結果】食道閉鎖症モデルを用いた吻合手技を被験者に課し、各被験者の手技を最初に人の目で「check 表」「エラー項目」「時間」を用いて評価した。次にビデオから検出した鉗子の動きと人が判定した手技優劣の関係性をAIで学習させ、上位88%・下位95%の精度で手技優劣が自動判定可能となった。この結果を解析することで今まで必要だった50項目以上の肉眼チェックが、わずか7項目チェックするだけで手技の優劣を判断できることが明らかになった。現在食道閉鎖症の手術画像を用いて、食道・迷走神経・気管を深層学習させ、各種構造物の自動認識を進めている。【まとめ】AI画像解析により内視鏡手技の優劣をビデオで判定可能となった。この結果から新たに効率的な手技判断基準を定めることができた。術中ナビゲーションは現在精度のさらなる向上を目指している。</p>

    DOI: 10.11239/jsmbe.annual61.127_2

    CiNii Research

  36. Refractory tracheoesophageal fistula treated using multi-stage surgery: A case report. Reviewed International journal

    Yoichi Nakagawa, Satoshi Makita, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda, Yaohui Guo

    Frontiers in pediatrics   Vol. 10   page: 1053154 - 1053154   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    A tracheoesophageal fistula (TEF) recurs in approximately 2%-13% of cases of esophageal atresia with TEF that are treated surgically. Currently, there is no consensus on the most effective treatment to prevent recurrent TEF (RTEF). Herein, we present a patient with type C esophageal atresia who underwent thoracoscopic esophago-esophageal anastomosis and TEF repair at 2 days old. However, RTEFs were observed at ages 3, 6, and 11 months, and thoracoscopic TEF repairs using a pleural patch, fascia lata graft, and pectoralis major myocutaneous (PMMC) flap were performed, respectively. A fourth recurrence led to mediastinitis, shock liver, disseminated intravascular coagulopathy, and a compromised respiratory status. Hence, laparoscopic esophageal transection was first performed to improve the respiratory condition by preventing the regurgitation of gastric contents. Once the patient was stable, a subtotal esophageal resection with TEF closure followed by gastric tube reconstruction was performed. In conclusion, we encountered a case of refractory RTEF that was repaired four times using various techniques, including a fascia lata graft and PMMC flap. However, TEF still recurred after these four operations. The final surgical strategy involved an esophageal transection as a palliative therapy, which improved the respiratory condition, followed by closure of the TEF and subtotal esophageal resection. Finally, esophageal reconstruction using a gastric tube after the complete remission of inflammation was effective. This multi-stage surgery was considered the only choice to rescue the patient and effectively prevent another recurrence.

    DOI: 10.3389/fped.2022.1053154

    Web of Science

    PubMed

  37. Preoperative imaging contributes to pathologically complete resection of the urachal remnant by determining an appropriate surgical approach without unnecessary and excessive surgical invasion: a retrospective study. Reviewed International journal

    Yoichi Nakagawa, Wataru Sumida, Hizuru Amano, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Satoshi Makita, Masamune Okamoto, Seiya Ogata, Aitaro Takimoto, Shunya Takada, Daiki Kato, Yousuke Gohda

    BMC urology   Vol. 22 ( 1 ) page: 207 - 207   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: The urachus is an embryonic structure that connects the bladder to the allantois during early embryonic development. Occasionally, it fails to disappear at birth, leading to a case of urachal remnant (UR). This study aimed to determine whether our policy for selecting an appropriate UR resection approach is valid. We performed preoperative imaging to examine whether UR continued toward the bladder apex. If so, the UR and bladder apex were excised using the trans-umbilical approach, in addition to laparoscopy, if necessary. If preoperative imaging indicated that the UR ended near the umbilicus, the UR from the umbilicus to the duct end was resected. Pathological evaluations were performed to determine the appropriateness of the surgical approach indicated by preoperative imaging. METHODS: We retrospectively reviewed pediatric patients with UR who underwent surgery between 2015 and 2021. Their background characteristics and surgical outcomes were evaluated. RESULTS: Twenty patients with UR were included (median age, 7 [interquartile range, 2-10.25] years). UR continued toward the bladder apex in 10 patients and ended near the umbilicus in 10 patients. Urachus tissue at the bladder site was observed when the UR and bladder apex were excised. When UR was resected from the umbilicus to the duct end, urachus tissue was not pathologically detected at the resection margin. CONCLUSION: Our policy results in complete resection without excessive surgical invasion.

    DOI: 10.1186/s12894-022-01153-x

    Web of Science

    PubMed

  38. Endoscopic injection sclerotherapy with polidocanol for cardiac varices in children and adolescents. Reviewed International journal

    Shinya Yokoyama, Yoji Ishizu, Takashi Honda, Norihiro Imai, Takanori Ito, Kenta Yamamoto, Akinari Hinoki, Wataru Sumida, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Kazuki Yokota, Hiroo Uchida, Masatoshi Ishigami

    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie     2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Like esophageal varices, cardiac varices are often treated with endoscopic variceal ligation (EVL). However, we previously reported that EVL for cardiac varices may be associated with a high risk of rebleeding from the ulcer if the O-ring spontaneously drops off early. The efficacy and safety of para-variceal endoscopic injection sclerotherapy (EIS) with polidocanol for the treatment of cardiac varices in children and adolescents were evaluated. METHODS: Eleven patients under 18 years of age with portal hypertension who underwent para-variceal EIS with polidocanol for cardiac varices with red signs, which were considered to be at high risk of bleeding, were retrospectively reviewed. RESULTS: One session of para-variceal polidocanol-EIS was performed for each of the 11 patients. One patient experienced temporary hypoxia due to aspiration of saliva when the tracheal intubation tube was removed after the procedure but recovered by endotracheal suctioning; there were no other adverse events. In six of the eight cases in which efficacy could be evaluated, eradication of cardiac varices was achieved. CONCLUSION: Para-variceal polidocanol-EIS may be considered instead of EVL for small cardiac varices with red signs in pediatric patients with cardiac varices.

    DOI: 10.1016/j.arcped.2022.11.016

    PubMed

  39. Adding a spur valve to laparoscopic portoenterostomy for patients with biliary atresia can achieve a high jaundice clearance rate and lower the number of episodes of cholangitis. Reviewed International journal

    Akihiro Yasui, Akinari Hinoki, Hizuru Amano, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Yoichi Nakagawa, Hiroo Uchida

    Pediatric surgery international   Vol. 38 ( 12 ) page: 1881 - 1885   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: This study aimed to evaluate the efficacy of adding a spur valve to laparoscopic portoenterostomy for patients with biliary atresia. METHODS: We retrospectively reviewed the records of all patients diagnosed with biliary atresia (BA) who underwent laparoscopic portoenterostomy (Lap-PE) between 2013 and 2021. The patients were divided into two groups: Lap-PE with a spur valve (spur group) and without it (control group). Perioperative management was the same in both groups. We compared patient backgrounds and clinical outcomes, including jaundice clearance and the number of postoperative cholangitis episodes. RESULTS: Of 63 patients reviewed, 16 received a spur valve. There were no statistically significant differences in the patient backgrounds between the groups. All patients in the spur group achieved jaundice clearance. The number of postoperative cholangitis episodes one year after surgery was significantly lower in the spur group than in the control group (1 [0-3] vs. 3 [0-9], p = 0.04). The jaundice-free survival rate with the native liver at one year after surgery was significantly higher in the spur group (100% vs. 53%, p = 0.01). CONCLUSIONS: Adding a spur valve during Lap-PE significantly lowered the number of cholangitis episodes 1 year after surgery.

    DOI: 10.1007/s00383-022-05230-y

    Web of Science

    PubMed

  40. Laparoscopic revision of Kasai portoenterostomy after initial laparoscopic portoenterostomy in patients with biliary atresia: a limited but positive effect on native liver survival. Reviewed International journal

    Daiki Kato, Hiroo Uchida, Hizuru Amano, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Yoichi Nakagawa

    Pediatric surgery international   Vol. 38 ( 12 ) page: 1821 - 1827   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: It is important for patients with biliary atresia (BA) to retain the native liver after Kasai portoenterostomy (PE). Laparoscopic PE (Lap-PE) is standard, whereas laparoscopic revision of PE (Lap-revision) is performed as needed. We report the medium-term outcomes of Lap-revision. METHODS: We retrospectively reviewed the demographics and outcomes of 63 patients who underwent Lap-PE between 2013 and 2021. Indications for revision included recurrent jaundice, repeat cholangitis, and persistent jaundice with temporary biliary excretion following the initial PE. We compared liver transplantation (LT) data of patients who underwent Lap-revision with those of patients who did not. RESULTS: Lap-revision was performed in 20 patients. Of those 17 (excluding the two who were jaundice-free before the age of 1, and the one who underwent open conversion for bleeding), 11 (65%) were jaundice-free 1 year after Lap-revision. The surgical parameters of LT did not differ between patients who underwent Lap-revision and those who did not. CONCLUSION: Lap-revision for patients with BA had a limited but positive effect on native liver survival and did not adversely affect subsequent LT. Therefore, Lap-revision could be second-line standard therapy in patients with BA who have demonstrated biliary drainage at least once after initial PE.

    DOI: 10.1007/s00383-022-05235-7

    PubMed

  41. Encouraging Young Pediatric Surgeons and Evaluation of the Effectiveness of a Pediatric Endosurgery Workshop by Self-Assessment and an Objective Skill Validation System. Reviewed International journal

    Katsuhiro Ogawa, Satoshi Ieiri, Toshihiko Watanabe, Yuko Bitoh, Hiroo Uchida, Atsuyuki Yamataka, Yasuharu Ohno, Masayuki Ohta, Masafumi Inomata, Elena Dorofeeva, Yulia Podurovskaya, Ekaterina Yarotskaya, Seigo Kitano

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 32 ( 12 ) page: 1272 - 1279   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Background: Japanese pediatric endosurgery experts conducted a workshop for young pediatric surgeons in Russia in collaboration with Russian expert pediatric surgeons. This study was aimed to develop a contributive workshop program and evaluate its impact on young pediatric surgeons. Methods: A 2-day pediatric endosurgery workshop was held in Moscow in February 2020. After conducting a needs assessment survey, Japanese and Russian faculties developed the workshop contents, including pre- and postworkshop skills assessments, lectures, and hands-on training. Skills assessments were performed using the objective skill validation system, the "A-Lap Mini," mimicking intestinal anastomosis. The trainees self-evaluated their knowledge and skills using a five-point scale. Results: Fifteen novice trainee participated and 14 (93.3%) completed the workshop program. The completion rate for the suturing task before and after the workshop was 40.0% (6/15) and 85.7% (12/14), respectively. The following five skill evaluation criteria, which were objectively evaluated: performance time changed from 751.6 ± 247.1 seconds to 780.0 ± 313.3 seconds (P > .05), number of full-thickness sutures improved from 1.0 ± 1.41 to 2.64 ± 0.84 (P = .003), area of wound-opening changed from 0.42 ± 0.83 mm2 to 0.53 ± 1.13 mm2 (P > .05), suture tension improved from 55.48% ± 19.51% to 61.95% ± 23.91% (P > .05), and maximum air leakage pressure improved from 3.76 ± 2.11 kPa to 8.42 ± 7.68 kPa (P > .05). Regarding the self-assessed questionnaire administered before and after the workshop, the confidence in endosurgery skills significantly improved as follows: forceps manipulation ability improved from 2.7 to 3.7 (P < .05), and suturing performance improved from 2.5 to 3.6 (P < .05). The usefulness of the workshop for clinical surgery was scored at 4.3. Conclusions: Quantitative skill evaluation with an automatic feedback function was useful for endosurgery training. Delivering feedback concerning the assessment results to the trainee helps them to determine the specific training requirements needed for clinical endosurgery.

    DOI: 10.1089/lap.2022.0152

    PubMed

  42. Biochemical markers to predict the development of gastrointestinal bleeding and esophageal varices after portoenterostomy in biliary atresia. Reviewed International journal

    Wataru Sumida, Takahisa Tainaka, Chiyoe Shirota, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Yoichi Nakagawa, Daiki Kato, Shinya Yokoyama, Yoji Ishizu, Hizuru Amano, Yaohui Guo, Akinari Hinoki, Hiroo Uchida

    Pediatric surgery international   Vol. 38 ( 12 ) page: 1799 - 1805   2022.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Gastrointestinal bleeding (GIB) due to esophageal varices (EV) is one of the factors that negatively impact native liver survival of patients with biliary atresia (BA). Gastrointestinal fibroscopy (GIF) is usually used to determine the presence of EVs; however, it requires general anesthesia. The aim of this study is to search for markers in blood tests obtained during routine check-ups that can predict the development of GIB. METHODS: Data of patients with BA who underwent portoenterostomy at our hospital from 2014 to 2020 were retrospectively reviewed. The patients' data were assigned to three groups according to specific time points: Group B, which included data at GIB; Group NB-T, which included data at GIF and EV treatment; and Group NB-NT, which included data at GIF without treatment. The data in Group B were compared to those of other groups. RESULTS: In our study, GIB occurred in 11 patients, and 12 cases and 8 cases were classified into Groups NB-NT and NB-T, respectively. Compared with the other groups, only ChE and M2BPGi in Group B showed statistically significant differences. CONCLUSIONS: ChE and M2BPGi are useful for predicting GIB.

    DOI: 10.1007/s00383-022-05243-7

    PubMed

  43. Combined negative pressure wound therapy with irrigation and dwell time and artificial dermis prevents infection and promotes granulation formation in a ruptured giant omphalocele: a case report. Reviewed International journal

    Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Satoshi Makita, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda

    BMC pediatrics   Vol. 22 ( 1 ) page: 680 - 680   2022.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Omphalocele is a congenital abdominal wall defect of the umbilical cord insertion site. A giant omphalocele, with a fascial defect > 5 cm in diameter and/or containing > 50% of the liver within the hernia sac, can be challenging for pediatric surgeons. Recently, negative pressure wound therapy has been reported as an effective management for giant omphaloceles; however, it is not recommended for an infected wound with necrotic tissue as it may exacerbate infection. We adopted negative pressure wound therapy with irrigation and dwell time (NPWTi-d) for a case of a ruptured giant omphalocele. Artificial membranes, followed by artificial dermis, were used to promote fibrous capsule formation, and then NPWTi-d was used to promote granulation while controlling infection. However, studies have not been conducted regarding NPWTi-d for ruptured giant omphaloceles; hence, we present our treatment experience with NPWTi-d for a giant omphalocele. CASE PRESENTATION: The patient was a boy born at 38 weeks and 3 days of gestation, weighing 1896 g. He was diagnosed with a ruptured giant omphalocele with a total liver and intestine defect hole of 10 cm × 10 cm. The patient underwent silo placement using an artificial mesh, followed by plicating the artificial mesh at 4 days of age. The herniated viscera were gradually reduced into the abdominal cavity; however, the defect size was still large. Hence, a collagen-based artificial dermis was patched on the defect hole. After creating a fresh and smooth granulated tissue, NPWTi-d was applied at 33 days of age to promote granulation and control infection. We used the 3 M™ V.A.C.® Ulta Therapy Unit with 3 M™ VeraFlo™ therapy. NPWTi-d was stopped at 60 days of age when the granulation tissue was well formed including at the artificial dermis site. The wound was managed with prostandin ointment and appropriate debridement, resulting in complete epithelialization at 5 months of age. CONCLUSIONS: Artificial membranes followed by artificial dermis were used to promote a fibrous capsule and artificial dermis granulation, which protects against organ damage. NPWTi-d achieved better control of infection and promoted wound healing. NPWTi-d combined with artificial dermis can effectively treat ruptured giant omphaloceles.

    DOI: 10.1186/s12887-022-03755-8

    Web of Science

    PubMed

  44. Laparoscopic Duodenal-Caudal Detachment Method: Early Experience of a Novel Technique for Malrotation with Volvulus in Neonates. Reviewed International journal

    Aitaro Takimoto, Hizuru Amano, Wataru Sumida, Chiyoe Shirota, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Seiya Ogata, Shunya Takada, Youichi Nakagawa, Daiki Kato, Yosuke Goda, Akinari Hinoki, Hiroo Uchida

    Journal of laparoendoscopic & advanced surgical techniques. Part A     2022.11

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    Purpose: A laparoscopic approach for malrotation is feasible and safe in hemodynamically stable neonates without intestinal necrosis; however, volvulus is associated with recurrence and conversion. We developed a novel approach using a laparoscopic duodenal-caudal detachment method to perform the Ladd procedure for neonates with volvulus under the limited view of laparoscopy. This study presents the results, effectiveness, and details of the method. Materials and Methods: In the laparoscopic duodenal-caudal detachment method, we first detached the adhesions around the duodenum, including the Ladd's band. After the adhesions were completely removed, the duodenum was freely drawn caudally, leading to the release of torsion. We retrospectively reviewed the medical records of patients who underwent surgery for malrotation of the volvulus at 30 days of age between January 2014 and September 2021. Results: Seven neonates underwent the laparoscopic duodenal-caudal detachment method and 13 underwent the open Ladd procedure. The new technique was performed in all 7 patients, and there were no conversions or recurrences. The operation time was significantly longer in the laparoscopic procedure group (55 minutes versus 111 minutes; P < .01). Conclusions: Our detorsion method, involving an initial incision of the Ladd's band, is safe and effective for neonates and may lead to an improvement in the conversion rates.

    DOI: 10.1089/lap.2022.0390

    Web of Science

    PubMed

  45. Development of wearable multi-lead ECG measurement device using cubic flocked electrode. Reviewed International journal

    Toshihiro Takeshita, Manabu Yoshida, Yusuke Takei, Atsushi Ouchi, Akinari Hinoki, Hiroo Uchida, Takeshi Kobayashi

    Scientific reports   Vol. 12 ( 1 ) page: 19308 - 19308   2022.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    This paper describes the fabrication and fundamental evaluation of the cubic flocked electrode (CFE), which is a dry electrode that is fabricated using electrostatic flocking technology. The development of a wearable multi-lead electrocardiogram (ECG) measurement device using the CFE is also reported. To enable the measurement of ECG signals with sufficient quality for medical applications, the occurrence of motion artifacts (MAs) is the most important problem to be overcome. Therefore, it is necessary to stabilize the contact between the patient's skin and the dry electrode. Because the CFE developed in this work offers both contact stability and flexibility, it is expected to enable ECG measurements with low MA levels. In this study, it is demonstrated that the number of MAs caused by respiration can be reduced when the CFE contact is made at a contact pressure of approximately 500 Pa using MA evaluation equipment that was developed in-house. Additionally, a wearable multi-lead ECG is designed and fabricated based on this contact pressure (500 Pa). The results of the demonstration experiment show that the ECG measurements are successful to the same extent as a conventional medical device.

    DOI: 10.1038/s41598-022-24043-6

    Web of Science

    PubMed

  46. Case report: A giant bilateral inguinal hernia requiring artificial mesh and multi-stage surgery in infancy; hernioplasty with silo placement to prevent acute compartment syndrome. Reviewed International journal

    Yoichi Nakagawa, Satoshi Makita, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Seiya Ogata, Shunya Takada, Daiki Kato, Yousuke Gohda, Guo Yaohui

    Frontiers in pediatrics   Vol. 10   page: 1030934 - 1030934   2022.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Hernioplasty for giant inguinal hernias can cause abdominal compartment syndrome (ACS) in adults but rarely does in infants. We encountered a case of a giant bilateral inguinal hernia in infancy complicated by ACS after hernioplasty. Silo placement via a skin incision effectively treated ACS, after which the abdominal wall was safely closed. Hernioplasty performed early in the clinical course can help expand the abdominal cavity and avoid ACS. Thus, hernioplasty should be performed earlier if the hernia size in the flank space gradually increases.

    DOI: 10.3389/fped.2022.1030934

    Web of Science

    PubMed

  47. Intraoperative indocyanine green fluorescence cholangiography can rule out biliary atresia: A preliminary report. Reviewed International journal

    Chiyoe Shirota, Akinari Hinoki, Takao Togawa, Shogo Ito, Wataru Sumida, Satoshi Makita, Hizuru Amano, Aitaro Takimoto, Shunya Takada, Masamune Okamoto, Yoichi Nakagawa, Daiki Kato, Hiroo Uchida

    Frontiers in pediatrics   Vol. 10   page: 1005879 - 1005879   2022.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: The prognosis of BA is known to be poor if definitive surgery is performed too late. Therefore, excluding BA as a diagnosis at an early stage is crucial. Conventional cholangiography requiring cannulation through the gallbladder may be unnecessarily invasive for patients, especially when ruling out BA. Therefore, a less invasive alternative such as indocyanine green (ICG) cholangiography, which does not require cannulation, should be established. In this study, we focused on excluding BA and confirmed the usefulness of intravenous ICG fluorescence cholangiography. To the best of our knowledge, this is the first preliminary study to report the use of intravenous ICG cholangiography for BA exclusion. METHODS: The study participants were patients who underwent liver biopsy and intraoperative cholangiography after they were suspected to have BA, between 2013 and 2022. ICG fluorescence cholangiography was performed on all patients who provided informed consent. RESULTS: During the study period, 88 patients underwent a laparoscopic liver biopsy and cholangiography. Among them, 65 (74%) were diagnosed with BA and underwent a subsequent laparoscopic Kasai portoenterostomy. BA was ruled out intraoperatively in 23 patients. Of the 23 patients in whom BA was ruled out, 14 underwent ICG cholangiography, 11 had gallbladder (GB) fluorescence, and 9 had both GB and common bile duct (CBD) fluorescence. Conventional cholangiography was very difficult in 2 of 23 cases: in 1 case, cannulation of the atrophic gallbladder was impossible, and cholecystectomy was indicated after multiple attempts; in 1 case, upstream cholangiography was not possible. In both cases, ICG fluorescence cholangiography successfully imaged the CBD and the GB. CONCLUSIONS: In conclusion, intravenous ICG fluorescence cholangiography might be a useful and less invasive diagnostic procedure that can rule out BA in infants.

    DOI: 10.3389/fped.2022.1005879

    Web of Science

    PubMed

  48. Circumumbilical incision for neonatal abdominal surgery: additional skin incision when there is difficulty in manipulating the intestine. Reviewed

    Yoichi Nakagawa, Akinari Hinoki, Hizuru Amano, Hiroo Uchida, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Daiki Kato

    Nagoya journal of medical science   Vol. 84 ( 4 ) page: 716 - 722   2022.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    This study aimed to evaluate the safety and effectiveness of circumumbilical incision (CUI) for neonates requiring intestinal anastomosis. Seventy neonates requiring intestinal anastomosis at our institution between 2003 and 2020 were included in this retrospective case-control study. Patients were classified into the CUI (25 patients: 36%) and transverse incision (TI) groups (45 patients: 64%). Postoperative complications and surgical outcomes were compared between the two groups. Intestinal perforation at the non-anastomotic site occurred significantly more often in the CUI group than in the TI group (3 patients: 12%, and 0 patients: 0%, respectively (p = 0.042)). There were no between-group differences regarding anastomotic leakages, anastomotic strictures, time to enteral feeding, operative time, and blood loss. Neonatal intestinal surgery employing CUI might be associated with increased intestinal perforation at the non-anastomotic site. Hesitating to enlarge the skin incision to maintain favorable cosmetic outcomes might cause severe injury to the delicate neonatal intestine during the surgical procedure owing to the restricted surgical field. When performing CUI, we suggest that the skin incision should be extended without hesitation whenever there is difficulty in manipulating the intestine.

    DOI: 10.18999/nagjms.84.4.716

    Web of Science

    PubMed

  49. 特集 小児外科を取り巻く最新テクノロジー Hirschsprung病に対する機械学習を用いた病理診断支援システムの開発 Reviewed

    天野 日出, 木村 和恵, 今井 佑太, 加藤 竜司, 中澤 温子, 城田 千代栄, 滝本 愛太朗, 住田 亙, 牧田 智, 岡本 眞宗, 安井 昭洋, 高田 瞬也, 中川 洋一, 加藤 大幾, 檜 顕成, 内田 広夫

    小児外科   Vol. 54 ( 10 ) page: 1007 - 1011   2022.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000254

    CiNii Research

  50. Laparoscopic definitive surgery for congenital biliary dilatation with aggressive hilar bile ductoplasty and complete resection of the intrapancreatic bile duct in pediatric patients is safe and effective, comparable to open surgery. Reviewed International journal

    Takahisa Tainaka, Chiyoe Shirota, Akinari Hinoki, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Hizuru Amano, Yujiro Tanaka, Hiroo Uchida

    Surgical endoscopy   Vol. 36 ( 10 ) page: 7352 - 7359   2022.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: After surgery for congenital biliary dilatation (CBD), hilar and hepatic bile duct stenosis and intrapancreatic bile duct remnants can cause many postoperative complications. We investigated the efficacy of laparoscopic surgery with aggressive bile ductoplasty and complete excision of the intrapancreatic bile duct in CBD patients compared to open surgery. METHODS: Pediatric patients who underwent surgery for CBD at our institution between 2006 and 2020 were divided into two groups: laparoscopic surgery (Lap group) and open surgery (Op group). Surgical outcomes were compared between the two groups. RESULTS: We enrolled 160 patients (85 in the Lap group and 75 in the Op group). Hilar bile ductoplasty was performed in 52 (61%) patients from the Lap group and 40 (53%) patients from the Op group. The operative time was significantly longer, the amount of blood loss was significantly lower, and the length of hospital stay was significantly shorter in the Lap group than in the Op group. Postoperative early and late complications occurred at a similarly low rate in both groups. When the surgical outcomes were compared between the group who underwent laparoscopic bile ductoplasty and the group that did not, postoperative early and late complications occurred similarly in both groups. CONCLUSIONS: Laparoscopic surgery for CBD with aggressive hilar bile ductoplasty and complete excision of the intrapancreatic bile duct is safe and effective, comparable to open surgery. However, it is necessary to verify whether long-term occurrence of hepatolithiasis similar to open definitive surgery can be obtained in the future.

    DOI: 10.1007/s00464-022-09132-x

    Web of Science

    PubMed

  51. Laparoscopic internal intestinal drainage of bile lakes in a patient with recurrence of jaundice after laparoscopic revision of Kasai portoenterostomy for biliary atresia: A case report Reviewed

    Gohda Yousuke, Uchida Hiroo, Hinoki Akinari, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Okamoto Masamune, Ogata Seiya, Takimoto Aitaro, Takada Shunya, Nakagawa Yoichi, Kato Daiki, Guo Yaohui

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY     2022.9

     More details

    Authorship:Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ases.13133

    Web of Science

    PubMed

  52. 特集 先天性胆道拡張症up-to-date 肝側合併症(肝内胆管狭窄)に対する肝内胆管形成術 Reviewed

    中川 洋一, 内田 広夫, 檜 顕成, 城田 千代栄, 住田 亙, 牧田 智, 岡本 眞宗, 尾形 誠弥, 滝本 愛太朗, 高田 瞬也, 加藤 大幾, 合田 陽祐

    小児外科   Vol. 54 ( 9 ) page: 904 - 907   2022.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000234

    CiNii Research

  53. 特集 先天性胆道拡張症up-to-date 腹腔鏡下先天性胆道拡張症根治術中に膵管損傷した2例 Reviewed

    加藤 大幾, 檜 顕成, 城田 千代栄, 住田 亙, 牧田 智, 天野 日出, 岡本 眞宗, 尾形 誠弥, 滝本 愛太朗, 高田 瞬也, 中川 洋一, 合田 陽祐, 内田 広夫

    小児外科   Vol. 54 ( 9 ) page: 924 - 927   2022.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/ps.0000000238

    CiNii Research

  54. Laparoscopic bile duct plasty for hilar bile duct stenosis (HBDS) in patients with congenital biliary dilatation: Diagnosis of HBDS by preoperative MRCP and laparoscopic strategy to relieve HBDS. Reviewed

    Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Akihiro Yasui, Aitaro Takimoto, Yaohui Guo

    Journal of hepato-biliary-pancreatic sciences     2022.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND/PURPOSE: Congenital biliary dilatation (CBD) is a disease associated with pancreaticobiliary maljunction. The most frequent postoperative complication is intrahepatic stones, which are caused by hilar bile duct stenosis (HBDS). METHODS: We retrospectively reviewed the records of patients who underwent primary surgery for CBD between 2013 and 2021. We evaluated images and videos of HBDS, the laparoscopic technique of releasing the stenosis, and its occurrence rate and compared intraoperative bile duct findings with those of preoperative magnetic resonance cholangiopancreatography (MRCP). RESULTS: There were 87 CBD cases in this study. HBDS occurred in 52% and preoperative MRCP for HBDS showed a 96% sensitivity and 74% specificity in this study. Bile duct plasty was performed in 45% of the cases and videos demonstrated typical methods of laparoscopic bile duct plasty. The mid- to long-term complications were hepatolithiasis in three patients, anastomotic site stricture in three, and postoperative obstruction in two. CONCLUSIONS: Our study revealed that preoperative imaging studies are useful for the prediction of HBDS. Our laparoscopic meticulous probing method for finding BDS reveals more intrahepatic BDS through magnification. Therefore, this may reduce the incidence of intrahepatic stones. Preoperative imaging and intraoperative findings can be complemented to plan management that reduces long-term complications.

    DOI: 10.1002/jhbp.1235

    Web of Science

    PubMed

  55. 食道疾患の診療 Ⅳ その他の食道疾患の診療 6 先天異常に伴う食道疾患 Invited

    内田 広夫

    臨床消化器内科   Vol. 37 ( 9 ) page: 1203 - 1210   2022.8

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:日本メディカルセンター  

    DOI: 10.19020/cg.0000002333

    CiNii Research

  56. Evaluation of minimally invasive surgical skills training: comparing a neonatal esophageal atresia/tracheoesophageal fistula model with a dry box. Reviewed International journal

    Kyoichi Deie, Yoichi Nakagawa, Hiroo Uchida, Akinari Hinoki, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Michimasa Fujiogi, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Takuya Maeda

    Surgical endoscopy   Vol. 36 ( 8 ) page: 6035 - 6048   2022.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Pediatric surgeons require highly advanced minimally invasive surgical skills to perform rare and complex surgeries in a very vulnerable population. We developed a neonatal esophageal atresia (EA) model to improve thoracoscopic surgical skills. This study aimed to evaluate the concurrent validity of the model by undertaking pre- and post-training skills assessments in two groups of students with no prior experience performing minimally invasive surgery, using the EA model and a dry box (DB). METHODS: A pilot study was performed. The participants were randomly divided into two groups: one trained using the DB and one trained using the EA model. Both groups practiced a minimally invasive surgical suture task. The task completion time, 29-point checklist score, modified suturing error sheet score, and three-dimensional forceps movement in both groups were compared pre-and post-training by video analysis. RESULTS: The EA model task was significantly more difficult than that of the DB. Both groups showed significant improvement in the task time, 29-point checklist score, and modified suturing error sheet score; however, the EA model training was more efficient in improving each error item. Regarding forceps movement, the EA model training significantly decreased wasted motion, whereas the DB was limited in this regard. CONCLUSIONS: Short-term training on the EA model, which was more technically demanding than the DB, decreased technical error and wasted motion, and allowed learners to acquire surgical skills more efficiently than training with the DB model. These facts revealed the concurrent validity of the EA model.

    DOI: 10.1007/s00464-022-09185-y

    Web of Science

    PubMed

  57. Thoracoscopic posterior tracheopexy during primary esophageal atresia repair ameliorate tracheomalacia in neonates: a single-center retrospective comparative cohort study. Reviewed International journal

    Akihiro Yasui, Akinari Hinoki, Hizuru Amano, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Yoichi Nakagawa, Hiroo Uchida

    BMC surgery   Vol. 22 ( 1 ) page: 285 - 285   2022.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Esophageal atresia (EA) is often associated with tracheomalacia (TM). The severity of TM symptoms varies widely, with serious cases requiring prolonged respiratory support and surgical treatment. Although we performed thoracoscopic posterior tracheopexy (TPT) during primary EA repair to prevent or reduce the symptoms of TM, few studies have investigated the safety and effectiveness of TPT during primary EA repair. Therefore, this study aimed to evaluate the safety and efficacy of TPT in neonates. METHODS: We retrospectively reviewed the records of all patients diagnosed with TM who underwent primary thoracoscopic EA repair between 2013 and 2020 at the Nagoya University Hospital. Patients were divided into two groups: TPT (TPT group) and without TPT (control group). TPT has been performed in all patients with EA complicated by TM since 2020. We compared patient backgrounds, surgical outcomes, postoperative complications, and treatment efficacy. RESULTS: Of the 22 patients reviewed, eight were in the TPT group and 14 were in the control group. There were no statistically significant differences in the surgical outcomes between the groups (operation time: p = 0.31; blood loss: p = 0.83; time to extubation: p = 0.30; time to start enteral feeding: p = 0.19; time to start oral feeding: p = 0.43). Conversion to open thoracotomy was not performed in any case. The median operative time required for posterior tracheopexy was 10 (8-15) min. There were no statistically significant differences in postoperative complications between the groups (chylothorax: p = 0.36; leakage: p = 1.00; stricture: p = 0.53). The respiratory dependence rate 30 days postoperative (2 [25%] vs. 11 [79%], p = 0.03) and the ratio of the lateral and anterior-posterior diameter of the trachea (LAR) were significantly lower in the TPT group (1.83 [1.66-2.78] vs. 3.59 [1.80-7.70], p = 0.01). CONCLUSIONS: TPT during primary EA repair for treatment of TM significantly lowered respiratory dependence rate at 30 days postoperative without increasing the risk of postoperative complications. This study suggested that TPT could improve TM associated with EA.

    DOI: 10.1186/s12893-022-01738-1

    Web of Science

    PubMed

  58. Laparoscopic definitive surgery for choledochal cyst is performed safely and effectively in infants. Reviewed International journal

    Takahisa Tainaka, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Hizuru Amano, Masamune Okamoto, Aitaro Takimoto, Yoko Kano, Akihiro Yasui, Yoichi Nakagawa, Akinari Hinoki, Hiroo Uchida

    Journal of minimal access surgery   Vol. 18 ( 3 ) page: 372 - 377   2022.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Laparoscopic definitive surgery for choledochal cyst (CC) in infants requires advanced skills because of their small size. If patients with a prenatal diagnosis of CC have any biliary symptoms, they need semi-emergency definitive surgery. This study aimed to estimate whether laparoscopic definitive surgery for CC can be performed safely and effectively in infants, especially when emergency surgery is required. PATIENTS AND METHODS: From January 2006 to December 2019, 21 patients under 1 year of age underwent laparoscopically or open definitive surgery, and 16 patients aged 3-5 years underwent laparoscopic surgery for CC at our institution. In cases of prenatal diagnosis, elective surgery (EL) was performed at about 6 months of age for patients with no biliary symptoms; the semi-emergency surgery (EM) was performed when patients had any biliary symptoms. Surgical outcomes were retrospectively compared between the Lap <1 y and Op <1 y groups and between the Lap <1 y and Lap 3-5 y groups. In addition, the surgical outcomes of those who underwent EM were also evaluated. RESULTS: Operative time was significantly longer, and blood loss was significantly lower in the Lap <1 y group than in the Op <1 y group. All surgical outcomes were similar between the Lap <1 y and Lap 3-5 y groups and between the EM and EL groups. CONCLUSION: Laparoscopic definitive surgery for CC in infants under 1 year of age is safe and feasible. Even semi-emergency laparoscopic surgery can be performed safely and effectively in small infants.

    DOI: 10.4103/jmas.JMAS_98_21

    Web of Science

    PubMed

  59. Patients with gastric volvulus recurrence have high incidence of wandering spleen requiring laparoscopic gastropexy and splenopexy. Reviewed International journal

    Yoichi Nakagawa, Hiroo Uchida, Hizuru Amano, Akinari Hinoki, Takahisa Tainaka, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Daiki Kato

    Pediatric surgery international   Vol. 38 ( 6 ) page: 875 - 881   2022.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Though gastric volvulus in neonates and infants resolves by conservative therapy and aging, some cases require surgical intervention. This study aimed to review the cases of gastric volvulus requiring surgical intervention and evaluate their characteristics. METHODS: We retrospectively reviewed gastric volvulus cases requiring surgical intervention. Surgical indication was persistent acute gastric volvulus and repeated hospitalization for gastric volvulus. We evaluated the characteristics of those cases requiring surgical intervention and the surgical results of laparoscopic gastropexy. RESULTS: The median age of patients included was 4 years (range: 1-6 years). All eight cases of gastric volvulus requiring sugery had congenital spleen diseases. Six of the eight cases suffered from a wandering spleen, while two cases presented with situs inversus with asplenia. Both splenopexy (preperitoneal distension balloon [PDB] or blunt separaion methods) and gastropexy were performed in cases with wandering spleen. No postoperative complications were reported in any of the eight cases, except the recurrence of gastric volvulus due to suture shedding in one case. CONCLUSION: Laparoscopic gastropexy for gastric volvulus and splenopexy for cases concomitant with wandering spleen were found to be effective surgical approaches. Both PDB and blunt separation methods for making extraperitoneal pockets for the spleen were employed successfully.

    DOI: 10.1007/s00383-022-05125-y

    Web of Science

    PubMed

  60. Serum matrix metalloproteinase-7 in biliary atresia: A Japanese multicenter study. Reviewed International journal

    Hirotaka Sakaguchi, Ken-Ichiro Konishi, Ryosuke Yasuda, Hideyuki Sasaki, Koichiro Yoshimaru, Takahisa Tainaka, Suguru Fukahori, Yukihiro Sanada, Itaru Iwama, Hiromichi Shoji, Masahiro Kinoshita, Toshiharu Matsuura, Jun Fujishiro, Hiroo Uchida, Masaki Nio, Yushiro Yamashita, Tatsuki Mizuochi

    Hepatology research : the official journal of the Japan Society of Hepatology   Vol. 52 ( 5 ) page: 479 - 487   2022.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Biliary atresia (BA) is among the commonest indications for liver transplantation (LT) in children. We examined whether serum matrix metalloproteinase-7 (MMP-7) is useful for diagnosis of BA in Japanese infants, and whether serum MMP-7 concentrations before and after Kasai portoenterostomy (KP) predicted LT within a year. METHODS: Subjects under 6 months old at eight pediatric centers in Japan were enrolled retrospectively, including patients with cholestasis and normal controls (NC) without liver disease. Patients with cholestasis were divided into groups representing BA versus cholestasis from other causes (non-BA). Serum samples were collected from patients with BA at diagnosis and 1 and 4 weeks after KP, as well as from non-BA and NC. RESULTS: Serum MMP-7 concentrations were significantly higher in BA at diagnosis (median, 89.1 ng/ml) than in non-BA (11.0; p < 0.001) or NC (10.3; p < 0.001). Receiver operating characteristic (ROC) analysis of MMP-7 for BA versus non-BA yielded an area under the ROC curve of 0.99 (95% confidence interval, 0.96-1.00). An optimal cut-off value of 18.6 ng/ml for serum MMP-7 in diagnosing BA demonstrated sensitivity and specificity of 100% and 90%, respectively. Serum MMP-7 before and 1 week and 4 weeks after KP did not differ significantly between BA requiring only KP and BA requiring LT after KP. CONCLUSION: Serum MMP-7 is a useful marker for diagnosis of BA in Japanese infants, but it could not predict LT within a year.

    DOI: 10.1111/hepr.13753

    Web of Science

    PubMed

  61. Utility of endoscopic retrograde cholangiopancreatography in management of pediatric pancreaticobiliary disease. Reviewed International journal

    Satoshi Makita, Hizuru Amano, Hiroki Kawashima, Akinari Hinoki, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Yoichi Nakagawa, Hiroo Uchida

    BMC pediatrics   Vol. 22 ( 1 ) page: 134 - 134   2022.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: The purpose of this study was to evaluate the utility of endoscopic retrograde cholangiopancreatography (ERCP) in pediatric patients with pancreaticobiliary diseases. METHODS: A retrospective review was performed on patients who underwent ERCP for the treatment of biliary tract disease and detailed examination of pancreatitis at our institution from January 1999 to December 2020. RESULTS: ERCP was performed for congenital biliary dilatation (CBD) (n = 42), choledocholithiasis (n = 9), common bile duct stenosis (n = 1), and several types of pancreatitis (n = 13). The only severe complication of ERCP was common bile duct injury. Three (5.8%) of 52 biliary diseases failed to be treated by ERCP. All patients with pancreatic disease were correctly diagnosed and treated. CONCLUSIONS: Endoscopic biliary drainage with a temporary stent was adequate for symptomatic relief in CBD. Stenting of the pancreatic duct was useful for improving the angulation and drainage of the pancreatic duct. ERCP was useful for understanding the anatomy of the pancreatic duct and revealing potential treatments. Therefore, ERCP and transendoscopic therapy are sufficiently feasible in pediatric patients and should be actively introduced for the investigation and treatment of pancreaticobiliary diseases.

    DOI: 10.1186/s12887-022-03207-3

    Web of Science

    PubMed

  62. 特集 プライマリケアにおける単純X線検査-ここまで読影することができる 胸部:各論 肺葉の異常 囊胞性肺疾患 Reviewed

    内田 広夫, 城田 千代栄, 田井中 貴久, 住田 亙

    小児内科   Vol. 54 ( 3 ) page: 423 - 431   2022.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:東京医学社  

    DOI: 10.24479/pm.0000000090

    CiNii Research

  63. Safety and feasibility of primary radical surgery for meconium peritonitis considering patients' general condition and perioperative findings. Reviewed

    Yoichi Nakagawa, Hiroo Uchida, Hizuru Amano, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Shunya Takada, Takuya Maeda

    Nagoya journal of medical science   Vol. 84 ( 1 ) page: 148 - 154   2022.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    We reviewed the outcomes of meconium peritonitis and evaluated the safety and feasibility of primary radical surgery for meconium peritonitis. A total of 21 cases of meconium peritonitis between 2006 and 2020 were retrospectively reviewed. The patients were classified into two groups based on the type of surgery: group I (primary radical surgery, n = 16) and group II (multistage surgery; drainage only or ileostomy, followed by elective surgery, n = 5). Patient backgrounds and surgical outcomes were compared between the two groups. The term of prenatal diagnosis, preoperative white blood cell count, and preoperative catecholamine use were not significantly different between the two groups. Group I included more mature neonates than group II (gestational age at birth, 35w1d vs 30w1d, p = 0.02; birth weight, 2.5 kg vs 1.1 kg, p < 0.01). Preoperative C-reactive protein was significantly lower in group I (0.37 mg/dL vs 2.8 mg/dL, p < 0.05). Operation time, blood loss, time to enteral feeding, and complication rates were not significantly different between the two groups. The surgical outcomes of primary radical surgery were comparable to those of multistage surgery, although the patients' backgrounds were different. Our strategy of selecting one-stage or multiple-stage surgery for treatment of meconium peritonitis, depending on the patient's general condition and degree of intestinal ischemia, was reasonable.

    DOI: 10.18999/nagjms.84.1.148

    Web of Science

    PubMed

  64. 血清MMP-7は胆道閉鎖症の葛西手術後1年以内の肝移植を予測できるか? Reviewed

    安田 亮輔, 坂口 廣高, 深堀 優, 吉丸 耕一朗, 松浦 俊治, 眞田 幸弘, 藤代 準, 田井中 貴久, 内田 広夫, 佐々木 英之, 仁尾 正記, 水落 建輝

    日本小児外科学会雑誌   Vol. 58 ( 1 ) page: 119 - 120   2022.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本小児外科学会  

  65. Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia. Reviewed

    Shirota C, Hinoki A, Tainaka T, Sumida W, Kinoshita F, Yokota K, Makita S, Amano H, Nakagawa Y, Uchida H

    World journal of gastrointestinal surgery   Vol. 14 ( 1 ) page: 56 - 63   2022.1

     More details

    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4240/wjgs.v14.i1.56

    PubMed

  66. 胆道拡張症術後肝内結石への DBERC 中に小腸穿孔をきたし、腹腔鏡下穿孔部閉鎖+内視鏡下採石した1例 Reviewed

    中川 洋一, 内田 広夫, 檜 顕成, 城田 千代栄, 住田 亙, 牧田 智, 岡本 眞宗, 尾形 誠弥, 滝本 愛太朗, 高田 瞬也, 加藤 大幾, 合田 陽祐

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 45 ( 0 ) page: 77 - 78   2022

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.45.0_77

    CiNii Research

  67. 多発肝内胆管狭窄を伴う先天性胆道拡張症術後難治性肝内結石の1例 Reviewed

    牧田 智, 内田 広夫, 檜 顕成, 城田 千代栄, 住田 亙, 天野 日出, 岡本 眞宗, 尾形 誠弥, 滝本 愛太朗, 高田 瞬也, 中川 洋一, 加藤 大幾, 合田 陽祐

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 45 ( 0 ) page: 74 - 75   2022

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.45.0_74

    CiNii Research

  68. Multi-class prediction for improving intestine segmentation on non-fecal-tagged CT volume Reviewed

    Oda, H; Hayashi, Y; Kitasaka, T; Takimoto, A; Hinoki, A; Uchida, H; Suzuki, K; Oda, M; Mori, K

    MEDICAL IMAGING 2022: COMPUTER-AIDED DIAGNOSIS   Vol. 12033   2022

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1117/12.2611441

    Web of Science

  69. 特集 小児外科疾患の家族内発生 胆道閉鎖症の家族内発症 Reviewed

    安井 昭洋, 内田 広夫, 城田 千代栄, 住田 亙, 横田 一樹, 牧田 智, 岡本 眞宗, 滝本 愛太朗, 高田 瞬也, 中川 洋一

    小児外科   Vol. 53 ( 12 ) page: 1288 - 1290   2021.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2022081278

    CiNii Research

  70. <Editors' Choice> Long-term outcomes of the partial splenectomy for hypersplenism after portoenterostomy of patients with biliary atresia. Reviewed

    Takahisa Tainaka, Akinari Hinoki, Yujiro Tanaka, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Kazuo Oshima, Hizuru Amano, Aitaro Takimoto, Yoko Kano, Hiroo Uchida

    Nagoya journal of medical science   Vol. 83 ( 4 ) page: 765 - 771   2021.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Massive splenomegaly and hypersplenism in patients with biliary atresia after Kasai portoenterostomy were treated with partial splenic embolization or total splenectomy. We performed partial splenectomy to reduce the complications of partial splenic embolization and avoid overwhelming post-splenectomy infection. This study aimed to evaluate the long-term effects of partial splenectomy for hypersplenism on postoperative liver and spleen function in patients with biliary atresia. Among jaundice-free patients with biliary atresia who underwent Kasai portoenterostomy between January 1992 and December 2012, 15 underwent partial splenectomy for massive splenomegaly and hypersplenism at our institution. Changes in the laboratory data 10 years post partial splenectomy were retrospectively investigated, and these along with the latest data were measured. A total of four patients (27%) required living-donor liver transplantation after partial splenectomy, a proportion similar to those who did not undergo partial splenectomy. Compared to the preoperative baseline, the platelet counts were significantly higher at 1 and 3 years after surgery (p < 0.05). Aspartic aminotransferase-to-platelet ratio index was significantly lower at 1, 7, and 10 years after partial splenectomy (p < 0.05). No further surgeries were required for hypersplenism after partial splenectomy over 10 years, and there were no cases of overwhelming post-splenectomy infection after partial splenectomy. Partial splenectomy is safe and effective for the treatment of hypersplenism with biliary atresia over a long time period. It could be considered as an alternative to partial splenic embolization as it can suppress hypersplenism for a long time and induces fewer postoperative complications.

    DOI: 10.18999/nagjms.83.4.765

    Web of Science

    PubMed

  71. Single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) for inguinal hernia with prolapsed ovary. Reviewed

    Shirota C, Tainaka T, Sumida W, Yokota K, Makita S, Amano H, Okamoto M, Takimoto A, Yasui A, Nakagawa Y, Hinoki A, Uchida H

    Surgical endoscopy     2021.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Surgical Endoscopy  

    Background: Most studies reporting the outcomes of laparoscopic ovarian prolapsed hernia operations with large sample sizes are based on intracorporeal closure, while studies on extraperitoneal closure have limited sample sizes. We proactively used the single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) technique and obtained favorable outcomes, which we report in this paper. Methods: We retrospectively reviewed patients who had undergone laparoscopic surgery for inguinal hernia at our institution. They were retrospectively classified into two groups based on the pre- or intraoperative diagnosis of hernia with a prolapsed ovary, namely the prolapse group and the non-prolapse group, respectively. The data were statistically analyzed and p < 0.05 was considered statistically significant. Results: A total of 771 subjects underwent SILPEC during the study period, including 400 girls. Among them, 63 girls were diagnosed with an ovarian prolapsed hernia. SILPEC was successfully performed through a single port in all cases, with a single exception, in whom the forceps was inserted directly through the right lower quadrant to pull up the ovary. The duration of surgery in the prolapse group was not higher than that in the non-prolapse group. During the SILPEC surgery, the ovaries were successfully reverted into the abdominal cavity by external compression of the inguinal area alone in 38 of the 63 patients. In the remaining 25 cases, the ovaries were reverted into the abdominal cavity by external compression of the inguinal area and traction of the round ligament with forceps. None of these cases failed to return to the ovaries. Conclusion: Our study results indicate that SILPEC may be performed safely for the treatment of ovarian prolapsed inguinal hernia. Since the ovary and fallopian tube are close to the internal inguinal ring due to the short round ligament, the procedure requires careful suturing with traction of the round ligament.

    DOI: 10.1007/s00464-021-08777-4

    Scopus

    PubMed

  72. Factors associated with bleeding after endoscopic variceal ligation in children Reviewed

    Yokoyama Shinya, Ishizu Yoji, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ito Takanori, Hinoki Akinari, Sumida Wataru, Shirota Chiyoe, Tainaka Takahisa, Makita Satoshi, Yokota Kazuki, Uchida Hiroo, Fujishiro Mitsuhiro

    PEDIATRICS INTERNATIONAL   Vol. 63 ( 10 ) page: 1223 - 1229   2021.10

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatrics International  

    Background: Endoscopic variceal ligation (EVL) is a widely accepted treatment for esophagogastric varices in patients with portal hypertension (PHT). It is used for urgent treatment and prophylactic treatment of esophagogastric varices in pediatric as well as adult patients. However, major life-threatening adverse events such as early rebleeding can occur. Although early rebleeding after EVL among children and adolescents has been reported, the risk factors remain obscure. This study evaluated the risk factors for early rebleeding after EVL in children and adolescents. Methods: The subjects were children and adolescents (<18 years) with PHT who underwent EVL for esophagogastric varices. Early rebleeding was defined as hematemesis, active bleeding, or blood retention in the stomach, confirmed by esophagogastroduodenoscopy from 2 h to 5 days after EVL. Results: A total of 50 EVL sessions on 22 patients were eligible for this study. There were four episodes of early rebleeding. No other major adverse event has occurred. Multivariate analysis showed that EVL implemented at cardiac varices just below the esophagogastric junction (EGJ), within 5 mm from the EGJ, is the independent factor for a higher risk of early rebleeding: odds ratio 18.2 (95% confidence interval: 1.40–237.0), P = 0.02. Conclusions: Children and adolescents who undergo EVL for cardiac varices just below the EGJ have a higher risk of early rebleeding than those who do not.

    DOI: 10.1111/ped.14614

    Web of Science

    Scopus

    PubMed

  73. SERUM MATRIX METALLOPROTEINASE-7 IN JAPANESE INFANTS WITH BILIARY ATRESIA Reviewed

    Mizuochi, T; Sakaguchi, H; Konishi, KI; Yasuda, R; Kinoshita, M; Fukahori, S; Shoji, H; Yoshimaru, K; Matsuura, T; Sanada, Y; Tainaka, T; Uchida, H; Sasaki, H; Iwama, I; Fujishiro, J; Nio, M

    HEPATOLOGY   Vol. 74   page: 1178A - 1178A   2021.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Web of Science

  74. Late postoperative complications of congenital biliary dilatation in pediatric patients: a single-center experience of managing complications for over 20 years Reviewed

    Amano Hizuru, Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Tanaka Yujiro, Hinoki Akinari, Kawashima Hiroki, Uchida Hiroo

    SURGERY TODAY   Vol. 51 ( 9 ) page: 1488 - 1495   2021.9

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Surgery Today  

    Purpose: To investigate late complications after surgery for congenital biliary dilatation (CBD). Methods: We retrospectively reviewed the patients treated for late postoperative complications of extrahepatic bile duct resection with bilioenteric anastomosis for CBD at our hospital between 1999 and 2019. Results: Twenty-seven complications, including bile duct stenosis with (n = 19) or without (n = 3) hepatolithiasis, remnant intrapancreatic bile duct (n = 2), intestinal obstruction (n = 2), and refractory cholangitis (n = 1) were treated in 26 patients. The median age at radical surgery and the initial treatment of complications was 3 years, 2 months and 14 years, 5 months, respectively. The median period from radical surgery to initial treatment of complications was 7 years, 1 month. Before 2013, bile duct stenosis was initially treated with bile duct plasty (n = 11) or hepatectomy (n = 3), and 71.4% (n = 10) of patients needed further treatment; after 2013, double-balloon endoscopic retrograde cholangiography (DBERC) was used (n = 8), and 25% (n = 2) of patients needed further treatment. Patients with remnant intrapancreatic bile duct, intestinal obstruction, and refractory cholangitis required surgery. Conclusion: Long-term follow-up is necessary after surgery for congenital biliary dilatation. DBERC is thus considered to be useful for bile duct stenosis management.

    DOI: 10.1007/s00595-021-02238-0

    Web of Science

    Scopus

    PubMed

  75. 血清MMP-7は胆道閉鎖症の肝移植予測マーカーとなりうるか? Reviewed

    安田 亮輔, 坂口 廣高, 深堀 優, 吉丸 耕一朗, 松浦 俊治, 眞田 幸弘, 藤代 準, 田井中 貴久, 内田 広夫, 佐々木 英之, 仁尾 正記, 水落 建輝

    日本小児栄養消化器肝臓学会雑誌   Vol. 35 ( Suppl. ) page: 106 - 106   2021.9

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本小児栄養消化器肝臓学会  

  76. An imaging study on tracheomalacia in infants with esophageal atresia: the degree of tracheal compression by the brachiocephalic artery is a good indicator for therapeutic intervention Reviewed

    Sumida Wataru, Tainaka Takahisa, Shirota Chiyoe, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Yasui Akihiro, Okamoto Masamune, Nakagawa Yoichi, Hinoki Akinari, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL     2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    Purpose: Tracheomalacia (TM) is a frequent complication after esophageal atresia (EA) repair. This study aimed to review patients who underwent aortopexy for TM after EA repair and to compare their imaging features. Methods: The patients who underwent thoracoscopic EA repair and contrast-enhanced computed tomography (CECT) at our hospital between 2013 and 2020 were retrospectively reviewed. The ratio of the lateral and anterior–posterior diameter of the trachea (LAR) where the brachiocephalic artery (BCA) crosses the trachea was defined. The LAR of the patients who underwent CECT for asymptomatic pulmonary disease was set as a normal reference. The Z-score of each LAR was calculated and compared between the patients that did or did not undergo aortopexy. Results: A total of 51 patients represented the controls, 5 patients underwent aortopexy, and 12 patients were discharged without surgery. The mean LARs in the patients who underwent aortopexy, did not undergo aortopexy, and controls were 3.54, 1.54, and 1.15, respectively. The mean Z-score of the aortopexy group was 21.2. After successful aortopexy, each patient’s LAR decreased to < 1.5. Conclusion: Aortopexy was preferred if the trachea was compressed by the BCA. The LAR is a useful indicator for predicting the therapeutic effect of aortopexy.

    DOI: 10.1007/s00383-021-04985-0

    Web of Science

    Scopus

    PubMed

  77. Urinary N-1,N-12-diacetylspermine as a biomarker for pediatric cancer: a case-control study Reviewed

    Yokota Kazuki, Hinoki Akinari, Hiramatsu Kyoko, Amano Hizuru, Kawamura Machiko, Kuwatsuka Yachiyo, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Okamoto Masamune, Takimoto Aitaro, Yasui Akihiro, Nakagawa Yoichi, Uchida Hiroo, Kawakita Masao

    PEDIATRIC SURGERY INTERNATIONAL     2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    Purpose: Minimally invasive examinations are particularly important in pediatric patients. Although the significance of urinary N1,N12-diacetylspermine (DiAcSpm) as a tumor marker (TM) has been reported in many types of adult cancers, its usefulness in pediatric cancers has not been reported. This may be due to urinary DiAcSpm level variations with age. This study aims to measure the normal levels of urinary DiAcSpm in healthy individuals and investigate its usefulness as a TM in childhood cancer. Methods: Urinary samples were collected from pediatric patients with and without cancer. The urinary DiAcSpm levels were measured, and the values were compared. Results: A total of 32 patients with cancer and 405 controls were enrolled in the study. Of the 32 patients, 13 had neuroblastoma, 9 had malignant lymphoma (ML), and 10 had leukemia. In the control group, the urinary DiAcSpm values markedly fluctuated among those with young age, especially infants; meanwhile, the values converged among those aged roughly 10 years and above. The sensitivity of DiAcSpm was significantly different among the three types of cancers: neuroblastoma (30.8%), ML (77.8%), and leukemia (40%). Conclusion: The urinary DiAcSpm value is a useful TM for both screening and follow-up of ML.

    DOI: 10.1007/s00383-021-04987-y

    Web of Science

    Scopus

    PubMed

  78. Comparative study of open and laparoscopic Kasai portoenterostomy in children undergoing living donor liver transplantation for biliary atresia Reviewed

    Takeda Masahiro, Sakamoto Seisuke, Uchida Hajime, Shimizu Seiichi, Yanagi Yusuke, Fukuda Akinari, Uchida Hiroo, Yamataka Atsuyuki, Kasahara Mureo

    PEDIATRIC SURGERY INTERNATIONAL     2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    Purpose: The effectiveness of laparoscopic Kasai portoenterostomy (Laparoscopic-KPE) for biliary atresia (BA) has been reported but remains controversial. We reviewed our own cases and cases described in previous studies of liver transplantation (LT) for BA after Laparoscopic-KPE to investigate the efficacy of Laparoscopic-KPE. Methods: Subjects were children of ≤ 2 years old with LT for BA after KPE who underwent Laparoscopic-KPE (n = 10) or Open-KPE (n = 115) between 2009 and 2020. Propensity score matching was performed to reduce the effect of treatment selection bias. The clinical data regarding the preoperative characteristics and surgical results were compared. Results: The rates of hypoplastic portal vein and retrograde portal vein flow were lower in the Laparoscopic-KPE group than in the Open-KPE group (0 vs. 40.0%, p = 0.02 and 0 vs. 35.0%, p = 0.04). There was no marked difference in the operation time or duration of hepatectomy. For portal vein reconstruction, a vein graft was not required in the Laparoscopic-KPE group (0 vs. 35.0%, p = 0.03). No patients in the Laparoscopic-KPE group developed portal vein complications or required re-laparotomy for bowel perforation or re-bleeding, in contrast to the Open-KPE group (0 vs. 15.0% and 0 vs. 10.0%, respectively). Conclusion: Laparoscopic-KPE may reduce postoperative complications that necessitate re-laparotomy in LT.

    DOI: 10.1007/s00383-021-04994-z

    Web of Science

    Scopus

    PubMed

  79. Current thoracoscopic approach for mediastinal neuroblastoma in Japan-results from nationwide multicenter survey Reviewed

    Kawano Takafumi, Souzaki Ryota, Sumida Wataru, Shimojima Naoki, Hishiki Tomoro, Kinoshita Yoshiaki, Uchida Hiroo, Tajiri Tatsuro, Yoneda Akihiro, Oue Takaharu, Kuroda Tatsuo, Hirobe Seiichi, Koshinaga Tsugumichi, Hiyama Eiso, Nio Masaki, Inomata Yukihiro, Taguchi Tomoaki, Ieiri Satoshi

    PEDIATRIC SURGERY INTERNATIONAL     2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    Background: Minimally invasive surgery (MIS) is appropriate for the treatment of some neuroblastomas (NBs); however, the indications and technical issues are unclear. This study aimed to clarify the current status of MIS for mediastinal NB in Japan. Methods: Preliminary questionnaires requesting the numbers of neuroblastoma cases in which MIS was performed from 2004 to 2016 were sent to 159 Japanese institutes of pediatric surgery. Secondary questionnaires were sent to institutions with MIS cases to collect detailed data. Results: One hundred thirty-four (84.2%) institutions returned the preliminary questionnaire and 83 institutions (52.2%) reported a total of 1496 operative cases. MIS was performed for 175 (11.6%) cases. Among the 175 cases, completed forms of 140 patients were returned and 40 (male, n = 28; female, n = 12) cases had mediastinal NB. Fourteen patients received thoracoscopic biopsy, none were converted to thoracotomy. Twenty-eight patients received MIS for radical resection, none were converted to thoracotomy. Perioperative complications (Horner’s syndrome) were recognized after radical resection in one (2.5%) case. Conclusions: MIS was performed in a limited number of mediastinal NB cases. A thoracoscopic approach would be feasible for mediastinal NB.

    DOI: 10.1007/s00383-021-04998-9

    Web of Science

    Scopus

    PubMed

  80. Clinical characteristics and outcomes of the right congenital diaphragmatic hernia compared to the left: a 10-year single-center experience Reviewed

    Okamoto Masamune, Amano Hizuru, Uchida Hiroo, Hinoki Akinari, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Yasui Akihiro, Nakagawa Yoichi

    PEDIATRIC SURGERY INTERNATIONAL     2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    Purpose: The features of right-sided congenital diaphragmatic hernias (RCDHs) are quite different from those of left-sided CDHs (LCDHs). We have summarized the features of RCDHs experienced in our institution. Methods: This retrospective study analyzed the cases of patients with CDH registered at our institution between 2011 and 2020. Defects on each side were compared based on prenatal diagnosis, medical treatment, type of surgery, and outcomes. Results: A total of 101 patients underwent surgery at our institution during the neonatal period, and 11 had RCDHs. RCDHs and LCDHs were significantly different in terms of extracorporeal membrane oxygenation (36% vs. 6%, p = 0.002), patch repair (81% vs. 28%, p < 0.001), recurrence rate (36% vs. 11%, p = 0.022), and length of hospital stay (117 days vs. 51 days, p = 0.012). The severity of the fetal diagnosis did not reflect postnatal severity. All patients with RCDH survived to discharge, and there was no significant difference in survival rate between the right and left sides. Conclusion: Neonates with RCDH required more intensive treatments; however, the survival rate was comparable between RCDH and LCDH. RCDH was significantly different from LCDH and an optimal treatment strategy for RCDHs should be established.

    DOI: 10.1007/s00383-021-04999-8

    Web of Science

    Scopus

    PubMed

  81. Double common bile duct associated with pancreaticobiliary maljunction Reviewed

    Yamada Kenta, Ishikawa Takuya, Ohno Eizaburo, Iida Tadashi, Suzuki Hirotaka, Uetsuki Kota, Yashika Jun, Yoshikawa Masakatsu, Takami Hideki, Inokawa Yoshikuni, Uchida Hiroo, Kawashima Hiroki, Fujishiro Mitsuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 3 ) page: 655 - 661   2021.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Nagoya Journal of Medical Science  

    A 45-year-old female was admitted to the hospital with a diagnosis of acute pancreatitis. A computed tomography scan showed two extrahepatic bile ducts. Magnetic resonance cholangiopancreatography suggested a stone in one of the bile ducts. Endoscopic retrograde cholangiopancreatography revealed two extrahepatic bile ducts joining at the hilum of the liver accompanied with pancreaticobiliary maljunction. Sphincterotomy was performed and a protein plug was drained from the bile duct. Several treatment options were discussed, and the patient was treated with laparoscopic cholecystectomy without extrahepatic bile duct resection and planned to be followed up considering the risk of carcinogenesis in the bile ducts.

    DOI: 10.18999/nagjms.83.3.655

    Web of Science

    Scopus

    PubMed

  82. Development of a novel diagnostic system for bile duct cancer using urinary metabolites. Reviewed

    Amano Hizuru, Hinoki Akinari, Uchida Hiroo, Yokota Kazuki, Ishigaki Takashi, Sakairi Minoru, Abe Mayumi, Terui Yasushi, Oda Hirohisa, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Takimoto Aitaro, Okamoto Masamune, Yasui Akihiro, Nakagawa Yoichi

    CANCER RESEARCH   Vol. 81 ( 13 )   2021.7

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  83. A patient with very early onset FH-deficient renal cell carcinoma diagnosed at age seven Reviewed

    Taniguchi Rieko, Muramatsu Hideki, Okuno Yusuke, Yoshida Taro, Wakamatsu Manabu, Hamada Motoharu, Shirota Chiyoe, Sumida Wataru, Hinoki Akinari, Tainaka Takahisa, Gotoh Yoshimitsu, Tsuzuki Toyonori, Tanaka Yukichi, Kojima Seiji, Uchida Hiroo, Takahashi Yoshiyuki

    FAMILIAL CANCER     2021.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Familial Cancer  

    Hereditary leiomyomatosis and renal cell cancer (HLRCC) is caused by heterozygous germline variants in the fumarate hydratase (FH) gene and is associated with increased susceptibility to cutaneous leiomyomas, uterine leiomyomas, and renal cell carcinoma (RCC). HLRCC-associated RCC usually occurs in the middle age, with the median age being 40–44 years. This report describes a seven-year-old (84-month-old) male who developed a large right kidney tumor with multiple cystic lesions that contained enhanced solid components. There was no evidence of distant metastasis. The male patient underwent right nephrectomy and has been recovering well without metastasis or recurrence. Pathological examination revealed that tumor cells with relatively prominent nucleoli and surrounded by halos, were located in a limited area. Immunohistochemical staining was negative for FH. Whole-exome sequencing identified his germline variant in the FH gene and its loss of heterozygosity in the tumor. At nine years (114 months) of age, the male patient showed no recurrence of the tumor. This was the youngest-onset case of HLRCC-associated RCC to date. This report may affect the starting age for future RCC-surveillance programs for patients with HLRCC.

    DOI: 10.1007/s10689-021-00268-8

    Web of Science

    Scopus

    PubMed

  84. Laparoscopic approach for abdominal neuroblastoma in Japan: results from nationwide multicenter survey Reviewed

    Kawano Takafumi, Souzaki Ryota, Sumida Wataru, Ishimaru Tetsuya, Fujishiro Jun, Hishiki Tomoro, Kinoshita Yoshiaki, Kawashima Hiroshi, Uchida Hiroo, Tajiri Tatsuro, Yoneda Akihiro, Oue Takaharu, Kuroda Tatsuo, Koshinaga Tsugumichi, Hiyama Eiso, Nio Masaki, Inomata Yukihiro, Taguchi Tomoaki, Ieiri Satoshi

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES     2021.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Surgical Endoscopy  

    Background: Some neuroblastoma (NB) cases are suitable for minimally invasive surgery (MIS), but indication and technical issue are unclear. We assessed the current status of MIS for abdominal NB after mass screening period in Japan. Methods: Preliminary questionnaires requesting the numbers of NB cases that underwent MIS from 2004 to 2016 were sent to 159 Japanese institutes of pediatric surgery. The secondary questionnaires were then sent to the institutions that reported MIS cases of NB in order to collect detailed data. Results: One hundred and thirty-four (84.2%) institutions responded to the preliminary questionnaires, and 83 (52.2%) reported managing operative cases. The total number of operative cases was 1496. MIS was performed for 175 (11.6%) cases, of which the completed forms of 140 patients were returned, including 100 abdominal NB cases. The male/female ratio was 51/49. Forty-seven cases underwent a laparoscopic biopsy, and 2 (4.3%) cases were converted to laparotomy due to bleeding. Sixty-five cases underwent MIS for radical resection, and 7 (10.8%) were converted to laparotomy. The reasons for open conversion were bleeding and severe adhesion. Regarding open conversion, there were no significant relationships between conversion and neo-adjuvant chemotherapy, biopsies, stage, size, or MYCN amplification. We found no relationship between resectability and vascular encasement in this study. There was relationship between the resected tumor size and the patients’ height, which was expressed using the following formula: y= 0.0316 x+ 1.4812 (x, patients height, y, tumor size; p = 0.004219, SE: 1.55566). Postoperative complications after radical resection were recognized in 7 (10.8%) cases. Conclusions: MIS was performed in limited cases of abdominal NB. A laparoscopic biopsy with careful attention to bleeding is feasible. The resected tumor size was shown to correlate with the patients’ height. Tumor size within 6 cm of maximum diameter can be resected safely.

    DOI: 10.1007/s00464-021-08599-4

    Web of Science

    Scopus

    PubMed

  85. Postoperative intestinal obstruction in patients with biliary atresia impedes biliary excretion and results in subsequent liver transplantation (vol 37, pg 229, 2021) Reviewed

    Takimoto Aitaro, Sumida Wataru, Amano Hizuru, Shirota Chiyoe, Tainaka Takahisa, Yokota Kazuki, Makita Satoshi, Yasui Akihiro, Kanou Yoko, Hinoki Akinari, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 37 ( 6 ) page: 835 - 835   2021.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Pediatric Surgery International  

    A correction to this paper has been published: https://doi.org/10.1007/s00383-021-04873-7.

    DOI: 10.1007/s00383-021-04873-7

    Web of Science

    Scopus

    PubMed

  86. NOVEL BIOMARKER DISCOVERY FOR CHILDHOOD RHABDOMYOSARCOMA USING URINARY METABOLITES Reviewed

    Amano Hizuru, Hinoki Akinari, Uchida Hiroo, Yokota Kazuki, Ishigaki Takashi, Sakairi Minoru, Abe Mayumi, Terui Yasushi, Oda Hirohisa, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Takimoto Aitaro, Kano Yoko, Okamoto Masamune, Yasui Akihiro, Nakagawa Yoichi

    PEDIATRIC BLOOD & CANCER   Vol. 68   page: S46 - S46   2021.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  87. 胆道閉鎖症におけるオキシステロール及び胆汁酸分析の有用性 a pilot study Reviewed

    小西 健一郎, 水落 建輝, 橋詰 直樹, 八木 実, 松浦 俊治, 田口 智章, 眞田 幸弘, 田井中 貴久, 内田 広夫, 佐々木 英之, 仁尾 正記, 藤代 準, 武井 一, 入戸野 博, 木村 昭彦

    日本小児外科学会雑誌   Vol. 57 ( 4 ) page: 786 - 787   2021.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本小児外科学会  

  88. Double-balloon endoscopic retrograde cholangiography can make a reliable diagnosis and good prognosis for postoperative complications of congenital biliary dilatation Reviewed

    Shirota Chiyoe, Kawashima Hiroki, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Amano Hizuru, Takimoto Aitaro, Hinoki Akinari, Uchida Hiroo

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 11052   2021.5

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Scientific Reports  

    Bile duct and anastomotic strictures and intrahepatic stones are common postoperative complications of congenital biliary dilatation (CBD). We performed double-balloon endoscopic retrograde cholangiography (DBERC) for diagnostic and therapeutic purposes after radical surgery. We focused on the effectiveness of DBERC for the treatment of postoperative complications of CBD patients. Bile duct and anastomotic strictures and intrahepatic stones are common postoperative complications of congenital biliary dilatation (CBD). We performed double-balloon endoscopic retrograde cholangiography (DBERC) for diagnostic and therapeutic purposes after radical surgery. We focused on the effectiveness of DBERC for the treatment of postoperative complications of CBD patients. This retrospective study included 28 patients who underwent DBERC (44 procedures) after radical surgery for CBD between January 2011 and December 2019. Strictures were diagnosed as “bile duct strictures” if endoscopy confirmed the presence of bile duct mucosa between the stenotic and anastomotic regions, and as “anastomotic strictures” if the mucosa was absent. The median patient age was 4 (range 0–67) years at the time of primary surgery for CBD and 27.5 (range 8–76) years at the time of DBERC. All anastomotic strictures could be treated with only by 1–2 courses of balloon dilatation of DBERC, while many bile duct strictures (41.2%) needed ≥ 3 treatments, especially those who underwent operative bile duct plasty as the first treatment (83.3%). Although the study was limited by the short follow-up period after DBERC treatment, DBERC is recommended as the first-line treatment for hepatolithiasis associated with biliary and anastomotic strictures in CBD patients, and it can be safely performed multiple times.

    DOI: 10.1038/s41598-021-90550-7

    Web of Science

    Scopus

    PubMed

  89. 特集 シミュレーションとナビゲーション 精索静脈瘤 Reviewed

    田井中 貴久, 田中 裕次郎, 檜 顕成, 城田 千代栄, 住田 亙, 横田 一樹, 牧田 智, 内田 広夫

    小児外科   Vol. 53 ( 5 ) page: 560 - 563   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2021229976

    CiNii Research

  90. Urinary biomarkers for monitoring treatment response in neuroblastoma patients. Reviewed

    Amano, H; Hinoki, A; Uchida, H; Yokota, K; Ishigaki, T; Sakairi, M; Abe, M; Takahashi, Y; Narita, A; Tainaka, T; Shirota, C; Sumida, W; Makita, S; Takimoto, A; Kano, Y; Yasui, A; Okamoto, M; Nakagawa, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 39 ( 15 )   2021.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1200/JCO.2021.39.15_suppl.e22008

    Web of Science

  91. A Retrospective Study on the Effect of Surgical Experiences of Laparoscopic Kasai Portenterostomy Reviewed

    Kurano Yui, Shirota Chiyoe, Hinoki Akinari, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 57 ( 3 ) page: 596 - 599   2021.4

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p><i>Purpose</i>: The treatment outcomes of patients with laparoscopic surgery for biliary atresia (laparoscopic portoenterostomy) were retrospectively evaluated to determine whether to limit the laparoscopic surgery for biliary atresia to fully experienced surgeons.</p><p><i>Methods</i>: We included 37 patients with laparoscopic portoenterostomy for biliary atresia at our institution from 2014 to 2018. Twelve patients were treated by a surgeon fully experienced in laparoscopic portoenterostomy (Group A) and 23 patients were treated by other surgeons (Group B). Jaundice reduction and jaundice-free survival of patients with the native liver in the two groups were compared.</p><p><i>Results</i>: Differences in age at the time of surgery, body weight, perioperative blood loss, time of drain removal, and time that milk or formula feeding resumed in both groups were not significant. The duration of surgery was significantly shorter in Group A than in Group B. The jaundice-free survival rates of patients with the native liver were 58.3% in Group A and 60.9% in Group B at 6 months after surgery, 66.7% in Group A and 65.2% in Group B at 1 year after surgery, and 58.3% in Group A and 56.5% in Group B at 2 years after surgery. No significant difference was observed.</p><p><i>Conclusions</i>: In this study, no significant difference in the rate of jaundice-free survival of patients with the native liver depending on the amount of surgical experience was observed under the guidance of an operator who was skilled in laparoscopic portoenterostomy.</p>

    DOI: 10.11164/jjsps.57.3_596

    CiNii Research

  92. A Japanese prospective multicenter study of urinary oxysterols in biliary atresia Reviewed

    Konishi Ken-ichiro, Mizuochi Tatsuki, Takei Hajime, Yasuda Ryosuke, Sakaguchi Hirotaka, Ishihara Jun, Takaki Yugo, Kinoshita Masahiro, Hashizume Naoki, Fukahori Suguru, Shoji Hiromichi, Miyano Go, Yoshimaru Koichiro, Matsuura Toshiharu, Sanada Yukihiro, Tainaka Takahisa, Uchida Hiroo, Kubo Yumiko, Tanaka Hiromu, Sasaki Hideyuki, Murai Tsuyoshi, Fujishiro Jun, Yamashita Yushiro, Nio Masaki, Nittono Hiroshi, Kimura Akihiko

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 4986   2021.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Scientific Reports  

    Diagnosis of biliary atresia (BA) can involve uncertainties. In the present prospective multicenter study, we considered whether urinary oxysterols represent a useful marker for diagnosis of BA in Japanese children. Subjects under 6 months old at 7 pediatric centers in Japan were prospectively enrolled, including patients with cholestasis and healthy controls (HC) without liver disease. Patients with cholestasis constituted 2 groups representing BA patients and others with cholestasis from other causes (non-BA). We quantitatively analyzed 7 oxysterols including 4β-, 20(S)-, 22(S)-, 22(R)-, 24(S)-, 25-, and 27-hydroxycholesterol by liquid chromatography/electrospray ionization-tandem mass spectrometry. Enrolled subjects included 14 with BA (median age 68 days; range 26–170) and 10 non-BA cholestatic controls (59; 14–162), as well as 10 HC (57; 25–120). Total urinary oxysterols were significantly greater in BA (median, 153.0 μmol/mol creatinine; range 24.1–486.7; P < 0.001) and non-BA (36.2; 5.8–411.3; P < 0.05) than in HC (2.7; 0.8–7.6). In patients with BA, urinary 27-hydroxycholesterol (3.61; 0.42–11.09; P < 0.01) was significantly greater than in non-BA (0.71; 0–5.62). In receiver operating characteristic (ROC) curve analysis for distinguishing BA from non-BA, the area under the ROC curve for urinary 27-hydroxycholesterol was 0.83. In conclusion, this first report of urinary oxysterol analysis in patients with BA indicated that 27-hydroxycholesterol may be a useful marker for distinguishing BA from other causes of neonatal cholestasis.

    DOI: 10.1038/s41598-021-84445-w

    Web of Science

    Scopus

    PubMed

  93. Identification of novel neuroblastoma biomarkers in urine samples Reviewed

    Yokota Kazuki, Uchida Hiroo, Sakairi Minoru, Abe Mayumi, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Oshima Kazuo, Makita Satoshi, Amano Hizuru, Hinoki Akinari

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 4055   2021.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Scientific Reports  

    Urine is a complex liquid containing numerous small molecular metabolites. The ability to non-invasively test for cancer biomarkers in urine is especially beneficial for screening child patients. This study attempted to identify neuroblastoma biomarkers by comprehensively analysing urinary metabolite samples from children. A total of 87 urine samples were collected from 54 participants (15 children with neuroblastoma and 39 without cancer) and used to perform a comprehensive analysis. Urine metabolites were extracted using liquid chromatography/mass spectrometry and analysed by Metabolon, Inc. Biomarker candidates were extracted using the Wilcoxon rank sum test, random forest method (RF), and orthogonal partial least squares discriminant analysis (OPLS-DA). RF identified three important metabolic pathways in 15 samples from children with neuroblastoma. One metabolite was selected from each of the three identified pathways and combined to create a biomarker candidate (3-MTS, CTN, and COR) that represented each of the three pathways; using this candidate, all 15 cases were accurately distinguishable from the control group. Two cases in which known biomarkers were negative tested positive using this new biomarker. Furthermore, the predictive value did not decrease in cases with a low therapeutic effect. This approach could be effectively applied to identify biomarkers for other cancer types.

    DOI: 10.1038/s41598-021-83619-w

    Web of Science

    Scopus

    PubMed

  94. Risk factors and outcomes of bile leak after laparoscopic surgery for congenital biliary dilatation Reviewed International journal

    Tanaka Yujiro, Tainaka Takahisa, Hinoki Akinari, Shirota Chiyoe, Sumida Wataru, Yokota Kazuki, Oshima Kazuo, Makita Satoshi, Amano Hizuru, Takimoto Aitaro, Kano Yoko, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 37 ( 2 ) page: 235 - 240   2021.2

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-020-04791-0

    Web of Science

  95. Thoracoscopic surgery for congenital lung cysts: an attempt to limit pulmonary resection in cases of lesions involving multiple lobes Reviewed International journal

    Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Takimoto Aitaro, Amano Hizuru, Hinoki Akinari, Ono Yasuyuki, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 37 ( 2 ) page: 213 - 221   2021.2

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-020-04793-y

    Web of Science

  96. Usefulness of web search queries for early detection of diseases in infants Reviewed

    Yamaguchi Shuji, Hinoki Akinari, Tsubouchi Kota, Amandu Hizuru, Tajima Akira, Uchida Hiroo

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 83 ( 1 ) page: 107 - 111   2021.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Nagoya Journal of Medical Science  

    Early detection of diseases is critical in infants. This study evaluates the usefulness of web searches in predicting diseases in order to encourage guardians to consult a doctor promptly if their children are ill. We collected six months of search queries from Yahoo! JAPAN Search between October 2016 and March 2017. Using a machine learning model, we investigated the accuracy of the search query’s ability to predict the diagnosis of biliary atresia and hypertrophic pyloric stenosis. Both diseases were modeled with an accuracy of approximately 80&, and symptoms related to the disease were significant features in the model. These findings suggest the possibility of detecting diseases from web search queries performed by guardians. Through future research, we intend to propose a method that uses web search queries for early detection of these diseases by providing appropriate and timely information to support the guardians of patients.

    DOI: 10.18999/nagjms.83.1.107

    Web of Science

    Scopus

    PubMed

  97. One-Stage Functional End-To-End Anastomosis Followed by Sutureless Abdominal Wall Closure for Colonic Atresia With Gastroschisis Reviewed

    Chiba Kosuke, Tanaka Yujiro, Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Oshima Kazuo, Makita Satoshi, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 57 ( 1 ) page: 22 - 26   2021

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>The patient was a newborn female with colonic atresia and gastroschisis. A silo was placed immediately after birth and surgery was scheduled the following day. Adhesive detachment was performed by washing the intestinal tract with saline. The oral and anal segments of the colonic atresia were identified, and functional end-to-end anastomosis was performed. Severe edema precluded the immediate return of the intestines to the abdominal cavity and required ongoing treatment with a silo. The intestines gradually returned to the abdominal cavity during the following week. The abdominal wall was closed on postnatal day 9 by a sutureless method. The patient's postoperative course was good, and full feeding was initiated on postnatal day 19. The patient was discharged from the hospital on postnatal day 32 and recovered without complications. In cases of gastroschisis with colonic atresia, a two-stage surgical procedure is commonly employed. However, functional end-to-end anastomosis using a linear stapler is also an effective method because anastomoses can be performed without regard to differences in intestinal caliber.</p>

    DOI: 10.11164/jjsps.57.1_22

  98. Laparoscopic One-Stage Radical Surgery for Congenital Biliary Dilatation With Biliary Perforation Reviewed

    Ishii Hiroki, Makita Satoshi, Yasui Akihiro, Takimoto Aitaro, Yokota Kazuki, Sumida Wataru, Tainaka Takahisa, Shirota Chiyoe, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 57 ( 5 ) page: 855 - 859   2021

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>A 21-month-old girl with chief complaints of vomiting and fever was admitted to a hospital and diagnosed as having congenital biliary dilatation. Magnetic resonance imaging performed on the sixth day of hospitalization revealed bile duct perforation, and the patient was transferred to our department for further treatment. A perforation approximately 2 cm in diameter was found at the confluence of the common bile duct and cystic duct. We concluded that biliary drainage and repair of the perforation would not improve her pathophysiology. Therefore, laparoscopic one-stage radical surgery was performed. In addition, bile duct plasty was performed to treat the severe intrahepatic bile duct membranous stenosis that were observed in the right and left bile ducts of the hepatic hilum. The patient was discharged without complications on the tenth postoperative day.</p><p>Two-stage surgery is the recommended treatment method for congenital biliary dilatation with biliary perforation. However, in recent years, there have been few reports showing that one-stage open radical surgery is useful. In this case, we successfully performed laparoscopic one-stage radical surgery for congenital biliary dilatation with biliary perforation. If laparoscopic radical surgery for congenital biliary dilatation is established at the institution, and the patient is in good general condition, laparoscopic one-stage radical surgery may be an effective modality for treating this condition.</p>

    DOI: 10.11164/jjsps.57.5_855

  99. Intestinal region reconstruction of ileus cases from 3D CT images based on graphical representation and its visualization Reviewed

    Hirohisa Oda, Yuichiro Hayashi, Takayuki Kitasaka, Yudai Tamada, Aitaro Takimoto, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Hayato Itoh, Masahiro Oda, Kensaku Mori

    Medical Imaging 2021: Computer-Aided Diagnosis   Vol. 11597   2021

     More details

    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:SPIE  

    DOI: 10.1117/12.2581261

    Web of Science

    Scopus

  100. 先天性胆道拡張症の晩期合併症についての検討 Reviewed

    城田 千代栄, 天野 日出, 檜 顕成, 住田 亙, 横田 一樹, 牧田 智, 岡本 眞宗, 滝本 愛太朗, 安井 昭洋, 高田 瞬也, 中川 洋一, 前田 拓也, 内田 広夫

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 44 ( 0 ) page: 50 - 51   2021

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.44.0_50

    CiNii Research

  101. 先天性胆道拡張症において術前MRI 画像による胆管狭窄部位の予測と術中胆管形成の検討 Reviewed

    中川 洋一, 内田 広夫, 檜 顕成, 城田 千代栄, 住田 亙, 横田 一樹, 牧田 智, 岡本 眞宗, 滝本 愛太朗, 安井 昭洋, 高田 舜也, 前田 拓也

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 44 ( 0 ) page: 72 - 73   2021

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.44.0_72

    CiNii Research

  102. Intestine Segmentation with Small Computational Cost for Diagnosis Assistance of Ileus and Intestinal Obstruction. Reviewed

    Hirohisa Oda, Yuichiro Hayashi, Takayuki Kitasaka, Aitaro Takimoto, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Masahiro Oda, Kensaku Mori

    Clinical Image-Based Procedures, Distributed and Collaborative Learning, Artificial Intelligence for Combating COVID-19 and Secure and Privacy-Preserving Machine Learning - 10th Workshop, CLIP 2021, Second Workshop, DCL 2021, First Workshop, LL-COVID19 2021, and First Workshop and Tutorial, PPML 2021, Held in Conjunction with MICCAI 2021, Strasbourg, France, September 27 and October 1(CLIP/DCL/LL-COVID19/PPML@MICCAI)   Vol. 12969   page: 3 - 12   2021

     More details

    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:Springer  

    DOI: 10.1007/978-3-030-90874-4_1

    Web of Science

    Other Link: https://dblp.uni-trier.de/db/conf/clip-ws/clip2019.html#OdaHKTHUSOM21

  103. 特集 小児がん手術の問題点-わたしはここを重視している 当院での腹腔鏡下腫瘍生検の実際 Reviewed

    住田 亙, 田井中 貴久, 城田 千代栄, 横田 一樹, 牧田 智, 滝本 愛太朗, 安井 昭洋, 天野 日出, 石井 宏樹, 檜 顕成, 内田 広夫

    小児外科   Vol. 52 ( 12 ) page: 1331 - 1335   2020.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2021085587

    CiNii Research

  104. A novel Lugol's iodine staining technique to visualize the upper margin of the surgical anal canal intraoperatively for Hirschsprung disease: a case series Reviewed International journal

    Yokota Kazuki, Amano Hizuru, Kudo Toyoki, Yamamura Takeshi, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Makita Satoshi, Takimoto Aitaro, Nakamura Masanao, Fujishiro Mitsuhiro, Hinoki Akinari, Uchida Hiroo

    BMC SURGERY   Vol. 20 ( 1 )   2020.12

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12893-020-00986-3

    Web of Science

  105. URINARY OXYSTEROLS IN BILIARY ATRESIA: A PROSPECTIVE MULTICENTER STUDY IN JAPAN Reviewed

    Konishi Ken-ichiro, Mizuochi Tatsuki, Takei Hajime, Yesuda Ryosuke, Sakaguchi Hirotaka, Ishihara Jun, Takaki Yugo, Kinoshita Masahiro, Hashizume Naoki, Fukahori Suguru, Shoji Hiromichi, Miyano Go, Yoshimaru Koichiro, Matsuura Toshiharu, Sanada Yukihiro, Tainaka Takahisa, Uchida Hiroo, Kubo Yumiko, Tanaka Hiromu, Sasaki Hideyuki, Murai Tsuyoshi, Fujishiro Jun, Yamashita Yushiro, Nio Masaki, Nittono Hiroshi, Kimura Akihiko

    HEPATOLOGY   Vol. 72   page: 224A - 225A   2020.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  106. Safe diagnostic management of malignant mediastinal tumors in the presence of respiratory distress: a 10-year experience Reviewed International journal

    Tanaka Tomoko, Amano Hizuru, Tanaka Yujiro, Takahashi Yoshiyuki, Tajiri Tatsuro, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Tani Yukiko, Hinoki Akinari, Uchida Hiroo

    BMC PEDIATRICS   Vol. 20 ( 1 )   2020.6

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12887-020-02183-w

    Web of Science

  107. Clinical characteristics and surgical outcomes of retroperitoneal tumors: a comprehensive data collection from multiple departments Reviewed International journal

    Sassa Naoto, Yokoyama Yukihiro, Nishida Yoshihiro, Yamada Suguru, Uchida Hiroo, Kajiyama Hiroaki, Nagino Masato, Kodera Yasuhiro, Gotoh Momokazu

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 5 ) page: 929 - 936   2020.5

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10147-020-01620-1

    Web of Science

  108. 特集 Hirschsprung病手術の現在 腹腔鏡補助下Swenson法 Reviewed

    横田 一樹, 内田 広夫, 田井中 貴久, 城田 千代栄, 住田 亙, 牧田 智, 大島 一夫, 滝本 愛太朗, 狩野 陽子

    小児外科   Vol. 52 ( 4 ) page: 369 - 373   2020.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2020230886

    CiNii Research

  109. Intestinal flow after anastomotic operations in neonates Reviewed International journal

    Ito Yasumasa, Asato Koichiro, Cho Inhyeok, Sakai Yasuhiko, Iwano Koji, Tainaka Takahisa, Uchida Hiroo

    COMPUTERS IN BIOLOGY AND MEDICINE   Vol. 118   2020.3

     More details

    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.compbiomed.2019.103471

    Web of Science

  110. Novel zinc alloys for biodegradable surgical staples Reviewed International journal

    Amano Hizuru, Miyake Koichi, Hinoki Akinari, Yokota Kazuki, Kinoshita Fumie, Nakazawa Atsuko, Tanaka Yujiro, Seto Yasuhiro, Uchida Hiroo

    WORLD JOURNAL OF CLINICAL CASES   Vol. 8 ( 3 ) page: 504 - 516   2020.2

     More details

    Publishing type:Research paper (scientific journal)  

    Web of Science

  111. 術中膵管損傷に対して内視鏡的に膵管ステントを挿入した1例 Reviewed

    城田 千代栄, 檜 顕成, 内田 広夫, 田井中 貴久, 住田 亙, 横田 一樹, 牧田 智, 天野 日出, 滝本 愛太朗, 安井 昭洋, 石井 宏樹

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 43 ( 0 ) page: 84 - 85   2020

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.43.0_84

  112. 小児腹腔鏡手術における肝内胆管形成術 Reviewed

    田井中 貴久, 内田 広夫, 城田 千代栄, 住田 亙, 横田 一樹, 牧田 智, 滝本 愛太朗, 安井 昭洋, 石井 宏樹, 檜 顕成

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 43 ( 0 ) page: 36 - 36   2020

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

    DOI: 10.34410/jspbm.43.0_36

  113. Visualizing intestines for diagnostic assistance of ileus based on intestinal region segmentation from 3D CT images Reviewed

    Hirohisa Oda, Kohei Nishio, Takayuki Kitasaka, Hizuru Amano, Aitaro Takimoto, Hiroo Uchida, Kojiro Suzuki, Hayato Itoh, Masahiro Oda, Kensaku Mori

    MEDICAL IMAGING 2020: COMPUTER-AIDED DIAGNOSIS   Vol. 11314   2020

     More details

    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:SPIE-INT SOC OPTICAL ENGINEERING  

    This paper presents a visualization method of intestine (the small and large intestines) regions and their stenosed parts caused by ileus from CT volumes. Since it is difficult for non-expert clinicians to find stenosed parts, the intestine and its stenosed parts should be visualized intuitively. Furthermore, the intestine regions of ileus cases are quite hard to be segmented. The proposed method segments intestine regions by 3D FCN (3D U-Net). Intestine regions are quite difficult to be segmented in ileus cases since the inside the intestine is filled with fluids. These fluids have similar intensities with intestinal wall on 3D CT volumes. We segment the intestine regions by using 3D U-Net trained by a weak annotation approach. Weak-annotation makes possible to train the 3D U-Net with small manually-traced label images of the intestine. This avoids us to prepare many annotation labels of the intestine that has long and winding shape. Each intestine segment is volume-rendered and colored based on the distance from its endpoint in volume rendering. Stenosed parts (disjoint points of an intestine segment) can be easily identified on such visualization. In the experiments, we showed that stenosed parts were intuitively visualized as endpoints of segmented regions, which are colored by red or blue.

    DOI: 10.1117/12.2548910

    Web of Science

    Scopus

    Other Link: https://dblp.uni-trier.de/db/journals/corr/corr2003.html#abs-2003-01290

  114. Identification and Validation of Novel Non-invasive Biomarkers in Patient Urine Samples for Diagnosis of New and Recurrent Neuroblastoma Reviewed International journal

    Yokota Kazuki, Uchida Hiroo, Hinoki Akinari, Sakairi Minoru, Abe Mayumi, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Sumida Wataru, Oshima Kazuo, Makita Satoshi, Takimoto Aitaro, Kano Yoko, Inada Kosuke

    PEDIATRIC BLOOD & CANCER   Vol. 66   page: S106 - S106   2019.12

     More details

    Publishing type:Research paper (scientific journal)  

    Web of Science

  115. 特集 ピーンチ!私はこうして切り抜けた 胆道閉鎖症 腹腔鏡手術中に門脈から出血 Reviewed

    内田 広夫, 田中 裕次郎, 田井中 貴久, 城田 千代栄, 住田 亙, 牧田 智, 横田 一樹, 滝本 愛太郎, 大島 一夫, 狩野 陽子, 稲田 亘佑

    小児外科   Vol. 51 ( 10 ) page: 1020 - 1023   2019.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2020041175

    CiNii Research

  116. Biodegradable Surgical Staple Composed of Magnesium Alloy.

    Amano H, Hanada K, Hinoki A, Tainaka T, Shirota C, Sumida W, Yokota K, Murase N, Oshima K, Chiba K, Tanaka Y, Uchida H

    Scientific reports   Vol. 9 ( 1 ) page: 14671   2019.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-019-51123-x

    PubMed

  117. Efficacy of and prognosis after steroid pulse therapy in patients with poor reduction of jaundice after laparoscopic Kasai portoenterostomy

    Tanaka Yujiro, Shirota Chiyoe, Tainaka Takahisa, Sumida Wataru, Oshima Kazuo, Makita Satoshi, Tanaka Tomoko, Tani Yukiko, Chiba Kosuke, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 35 ( 10 ) page: 1059-1063   2019.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-019-04537-7

    Web of Science

    PubMed

  118. Therapeutic strategy for thoracoscopic repair of esophageal atresia and its outcome

    Shirota Chiyoe, Tanaka Yujiro, Tainaka Takahisa, Sumida Wataru, Yokota Kazuki, Makita Satoshi, Oshima Kazuo, Tanaka Tomoko, Tani Yukiko, Uchida Hiroo

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 35 ( 10 ) page: 1071-1076   2019.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-019-04541-x

    Web of Science

    PubMed

  119. NON-INVASIVE SCREENING FOR DETECTING ESOPHAGOGASTRIC VARICES IN CHILDREN WITH BILIARY ATRESIA Reviewed International journal

    Yokoyama Shinya, Ishigami Masatoshi, Honda Takashi, Kuzuya Teiji, Ishizu Yoji, Ito Takanori, Shirota Chiyoe, Uchida Hiroo, Fujishiro Mitsuhiro

    HEPATOLOGY   Vol. 70   page: 200A - 200A   2019.10

     More details

    Publishing type:Research paper (scientific journal)  

    Web of Science

  120. Laparoscopic Kasai portoenterostomy is advantageous over open Kasai portoenterostomy in subsequent liver transplantation.

    Shirota C, Murase N, Tanaka Y, Ogura Y, Nakatochi M, Kamei H, Kurata N, Hinoki A, Tainaka T, Sumida W, Yokota K, Makita S, Oshima K, Uchida H

    Surgical endoscopy     2019.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00464-019-07108-y

    PubMed

  121. Spleen stiffness by 2-D shear wave elastography is the most accurate predictor of high-risk esophagogastric varices in children with biliary atresia.

    Yokoyama S, Ishigami M, Honda T, Kuzuya T, Ishizu Y, Ito T, Hirooka Y, Tanaka Y, Tainaka T, Shirota C, Chiba K, Uchida H, Fujishiro M

    Hepatology research : the official journal of the Japan Society of Hepatology     2019.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13381

    PubMed

  122. 特集 技術認定取得医が解説する高難度内視鏡外科手術 胆道閉鎖症に対する腹腔鏡による肝門部空腸吻合術 Reviewed

    内田 広夫

    小児外科   Vol. 51 ( 4 ) page: 393 - 398   2019.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    DOI: 10.24479/j00645.2019185000

    CiNii Research

  123. Relationship between Contact Pressure and Motion Artifacts in ECG Measurement with Electrostatic Flocked Electrodes Fabricated on Textile. Reviewed International journal

    Toshihiro Takeshita, Manabu Yoshida, Yusuke Takei, Atsushi Ouchi, Akinari Hinoki, Hiroo Uchida, Takeshi Kobayashi

    Scientific reports   Vol. 9 ( 1 ) page: 5897 - 5897   2019.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    To develop a wearable multi-lead electrocardiogram (ECG) measuring system, we fabricated the electrodes and wires by using electrostatic flocking technology on a textile. By using this technology, it was possible to fabricate many electrodes and wires, simultaneously. Also the flocked electrodes and wires had stretchability and washing resistance properties. To use dry electrodes, it is important to reduce the influence of motion artifacts (MAs). The results of the experiment with the skin phantom revealed that the contact pressure between the skin and the electrode is an important factor in MA reduction. Then, we conducted experiments with a human body to determine the relationship between the contact pressure and the MAs. Under the pressures of 200 Pa and 500 Pa, MAs were observed. Meanwhile, under the pressures of 1000 Pa, 2000Pa and 4000 Pa, the ECG signals under rest and deep breathing conditions were able to be measured without MAs. Considering the comfortability, the contact pressure from 1000 Pa to 2000 is preferable. Finally, we fabricated the wearable ECG measuring system and succeeded in measuring 18-lead ECG signals. The measured ECG waveform is in good agreement with the ECG waveform measured by a commercial system.

    DOI: 10.1038/s41598-019-42027-x

    Web of Science

    PubMed

  124. 静電植毛技術を用いた心電図測定用立体ドライ電極の作製と応用 Reviewed

    竹下 俊弘, 吉田 学, 竹井 裕介, 大内 篤, 檜 顕成, 内田 広夫, 小林 健

    エレクトロニクス実装学術講演大会講演論文集   Vol. 33 ( 0 ) page: 13A2-01   2019

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:一般社団法人エレクトロニクス実装学会  

    <p>心電図モニタリング用のドライ電極の開発を行った。ドライ電極を用いた心電図モニタリングにおいての課題は皮膚-電極間の安定した接触である。我々は立体構造の樹脂に銀メッキ加工を施した繊維を静電植毛することにより、体の形状に沿った形状であり、皮膚-電極間の安定した接触を実現した、ドライ電極の作製を行った。また作製したドライ電極を用いて心電図モニタリングウェアを作製し、医療的意義のある心電図測定に成功した。</p>

    DOI: 10.11486/ejisso.33.0_13a2-01

    CiNii Research

  125. 内視鏡外科手術における熟練医の追体験トレーニングシステムとその評価 Reviewed

    安藤 英由樹, 坂井 義治, 小濱 和貴, 内田 広夫, 出家 亨一, 松田 公志, 吉田 健志, 早石 直広

    生体医工学   Vol. 57 ( 0 ) page: S198_1 - S198_1   2019

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:公益社団法人 日本生体医工学会  

    <p>腹腔鏡手術は低侵襲性であることから普及が進んでいる。しかしながら、カメラを通じた状況把握、ポート留置部を支点とするため移動方向が手の動きと逆になる腹腔鏡用鉗子の利用など、手術の難易度が高く、習得に時間がかかることことから熟練者不足が問題となっている。また熟練医の不足は修練者のための教育に当てる時間も不足するという悪循環を生んでいる。従って、熟練者を短期間で養成し増やすための術式教育そのものが重要な課題である。本研究では、内視鏡外科手術は術野像がモニタによって同じ視野が「共有される」という特性を利用して、段階的な学習ステップに応じた、熟練者の適切かつスムースな動きを修練者が追体験することで、非言語的なスキルの伝達を行い、効果的なトレーニングを行うシステムである「追いトレ」を用いた場合の効果について、妥当性、効果の範囲、適応可能な範囲を明らかし、製品化・実用化・普及を実現するエビデンスを獲得するために、様々な内視鏡外科分野で十分な検証実験を踏まえたデータ取得とデータ解析を行なうことを目的とした。</p>

    DOI: 10.11239/jsmbe.Annual57.S198_1

  126. Spaciousness Filters for Non-contrast CT Volume Segmentation of the Intestine Region for Emergency Ileus Diagnosis

    Hirohisa Oda, Kohei Nishio, Takayuki Kitasaka, Benjamin Villard, Hizuru Amano, Kosuke Chiba, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Hayato Itoh, Masahiro Oda, Kensaku Mori

    MICCAI 2019   Vol. 11840   page: 104 - 114   2019

     More details

    Language:English   Publishing type:Research paper (other academic)   Publisher:Springer  

    DOI: 10.1007/978-3-030-32689-0_11

    Web of Science

    Other Link: https://dblp.uni-trier.de/db/conf/miccai/clip2019.html#OdaNKVACHUSIOM19

  127. Nuss procedure for patients with pectus excavatum with a history of intrathoracic surgery.

    Takanari K, Toriyama K, Kambe M, Nakamura Y, Uchibori T, Ebisawa K, Shirota C, Tainaka T, Uchida H, Kamei Y

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS     2018.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bjps.2018.12.027

    PubMed

  128. Air test as a simple method of screening for Hirschsprung's disease Reviewed

    Sumida W, Uchida H, Ono Y, Tanaka Y, Tainaka T, Shirota C, Yokota K, Oshima K, Chiba K

    Clin Radiol   Vol. 73 ( 12 ) page: 1041 - 1045   2018.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.crad.2018.08.008

    Web of Science

    Other Link: http://orcid.org/0000-0002-1818-6697

  129. Indications for total esophagogastric dissociation in children with gastroesophageal reflux disease Reviewed

    Yujiro Tanaka, Takahisa Tainaka, Hiroo Uchida

    Surgery Today   Vol. 48 ( 11 ) page: 971 - 977   2018.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Tokyo  

    Total esophagogastric dissociation (TED) is used to treat gastroesophageal reflux (GER) after failed fundoplication in neurologically impaired patients. It is now performed for some otherwise healthy patients with severe GER. In this procedure, the gastrointestinal tract is reconstructed in a non-physiological way with a Roux-en-Y esophagojejunal anastomosis and jejuno-jejunostomy. Although TED eliminates almost all GER, some patients experience late complications. In this review, we investigated the long-term outcomes after TED to determine the best indications. In total, 147 neurologically impaired patients and 28 neurologically normal patients were identified. The total rate of complications requiring re-operation was 17.2% in neurologically impaired patients and 32.1% in normal patients, both higher than the rates associated with fundoplication. Although most authors added pyloroplasty when there was a concern of gastric emptying, this sometimes caused bile reflux. Nutritional and metabolic complications, including dumping syndrome and chronic digestive malabsorption, were also reported to occur after TED. TED is an option for the treatment of neurologically impaired patients with recurrent GER after fundoplication or who are at a high risk of recurrence of GER with fundoplication. However, neurologically normal patients who have the ability to obtain nutrition orally should consider options other than TED, as postoperative complications are frequent.

    DOI: 10.1007/s00595-018-1636-9

    Web of Science

    Scopus

    PubMed

    Other Link: http://orcid.org/0000-0002-1818-6697

  130. A new laparoscopic triangle fixation technique for gastrostomy: a safe and effective procedure for reduction of the wound infection rate. Reviewed

    Michimasa Fujiogi, Yujiro Tanaka, Hizuru Amano, Kyoichi Deie, Keisuke Suzuki, Hiroshi Kawashima, Naruhiko Murase, Hiroo Uchida

    Nagoya journal of medical science   Vol. 80 ( 4 ) page: 497 - 503   2018.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Gastrostomy is often performed with fundoplication in handicapped children. We devised a new laparoscopic triangle fixation technique for gastrostomy. In this study, 100 patients underwent gastrostomy with fundoplication between January 2008 and January 2016. We retrospectively reviewed the early postoperative results between the new laparoscopic procedure (NLP) group (n = 63) and conventional procedure (CP) group (n = 37). In the CP, the gastrostomy tube was inserted with a purse-string ligature at the gastric wall, and the gastric wall was sutured to the peritoneum under a small laparotomy. In NLP, three sutures were placed on the gastric wall, forming the three sides of a triangle, and the tube was inserted into the center of the triangle. The ends of each suture were pulled directly through the abdominal wall using a laparoscopic percutaneous extraperitoneal closure needle to join the gastric wall and peritoneum. Both groups showed no significant differences in age, body weight, and external leakage rate. The wound infection rate was significantly lower in the NLP group. In conclusions, the NLP is straightforward and can achieve firm fixation between the stomach and abdominal wall by suturing in the form of a triangle. The NLP was associated with a lower complication rate, especially concerning infection.

    DOI: 10.18999/nagjms.80.4.497

    Web of Science

    Scopus

    PubMed

  131. Laparoscopically Assisted Anorectoplasty for Intermediate-Type Imperforate Anus: Comparison of Surgical Outcomes with the Sacroperineal Approach

    Ishimaru Tetsuya, Kawashima Hiroshi, Tainaka Takahisa, Suzuki Keisuke, Takami Shohei, Kakihara Tomo, Katoh Reiko, Aoyama Tomohiro, Uchida Hiroo, Iwanaka Tadashi

    JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES     2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2018.0330

    Web of Science

    PubMed

  132. Oral administration of eicosapentaenoic acid suppresses liver fibrosis in postoperative patients with biliary atresia

    Sumida Wataru, Uchida Hiroo, Tainaka Takahisa, Shirota Chiyoe, Hinoki Akinari, Kato Takazumi, Yokota Kazuki, Oshima Kazuo, Shirotuki Ryo, Chiba Kosuke, Tanaka Yujiro

    PEDIATRIC SURGERY INTERNATIONAL   Vol. 34 ( 10 ) page: 1059-1063   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-018-4313-6

    Web of Science

    PubMed

  133. Long-term outcomes and complications after laparoscopic-assisted anorectoplasty vs. posterior sagittal anorectoplasty for high- and intermediate-type anorectal malformation. Reviewed International journal

    Takahisa Tainaka, Hiroo Uchida, Yujiro Tanaka, Akinari Hinoki, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Kazuo Oshima, Kosuke Chiba, Tetsuya Ishimaru, Hiroshi Kawashima

    Pediatric surgery international   Vol. 34 ( 10 ) page: 1111 - 1115   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compare them to those after posterior sagittal anorectoplasty (PSARP). METHODS: Forty-five male patients with high and intermediate anorectal malformation (aged ≥ 4 years) who underwent LAARP or PSARP (LAARP 29, PSARP 16) from 1999 to 2013 were included. Postoperative complications and postoperative fecal continence were retrospectively evaluated and compared. Postoperative complications were also compared before and after introducing a urethroscope during fistula resection. RESULTS: Complications after LAARP and PSARP were seen in 12 vs. 2 cases (p = 0.09) of mucosal prolapse and in 9 vs. 1 case (p = 0.07) of posterior urethral diverticulum (PUD), respectively. The incidence of PUD decreased after introduction of a urethroscopy from 40% in 8/20 cases to 11% in 1/9 cases. No significant difference was found in terms of fecal continence in both groups. CONCLUSION: Through our study, greater improvement of postoperative fecal continence after LAARP has not been shown. LAARP was at higher risk for mucosal prolapse and PUD. However, precise dissection of the urethral fistula could be performed after the introduction of urethroscopy.

    DOI: 10.1007/s00383-018-4323-4

    Web of Science

    PubMed

  134. Investigation of the feasibility and safety of single-stage anorectoplasty in neonates with anovestibular fistula. Reviewed International journal

    Chiyoe Shirota, Keisuke Suzuki, Hiroo Uchida, Hiroshi Kawashima, Akinari Hinoki, Takahisa Tainaka, Wataru Sumida, Naruhiko Murase, Kazuo Oshima, Kosuke Chiba, Satoshi Makita, Yujiro Tanaka

    Pediatric surgery international   Vol. 34 ( 10 ) page: 1117 - 1120   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: Anovestibular fistula (AVF) is the most common type of anorectal malformation in females. Delayed anorectoplasty with fistula dilatation is commonly performed during infancy; however, we have been actively performing anorectoplasty in neonates. We report the surgical complications and postoperative defecation function associated with single-stage anorectoplasty performed in neonates. METHODS: Patients who underwent surgery for AVF between 2007 and 2017 at two institutions were retrospectively studied. The operation time, amount of bleeding, time to start oral intake, perioperative complications, and Kelly's score were compared among patients who underwent surgery as neonates and those who underwent surgery as infants. RESULTS: Eighteen neonates and 17 infants underwent anterior sagittal anorectoplasty. The median operation time and time to start oral intake were significantly shorter in the neonatal group (72 min; 3 days, respectively) than in the infant group (110 min, p = 0.0002; 5 days, p = 0.0024, respectively). Postoperative wound disruption was significantly more frequent in the infant group. Of the ten patients each in the neonatal and infant groups, there was no significant difference in Kelly's score at age ≥ 4 years. CONCLUSION: Single-stage anorectoplasty in neonates with AVF can be feasibly performed and does not impair postoperative defecation function. LEVELS OF EVIDENCE: III.

    DOI: 10.1007/s00383-018-4324-3

    Web of Science

    PubMed

  135. Introduction of resection of intrahepatic bile duct stenosis-causing membrane or septum into laparoscopic choledochal cyst excision. Reviewed International journal

    Yujiro Tanaka, Takahisa Tainaka, Wataru Sumida, Akinari Hinoki, Chiyoe Shirota, Naruhiko Murase, Kazuo Oshima, Ryo Shirotsuki, Kosuke Chiba, Hiroo Uchida

    Pediatric surgery international   Vol. 34 ( 10 ) page: 1087 - 1092   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: We previously showed that meticulous probing and resection of the intrahepatic bile duct stenosis (IHBDS)-causing membrane or septum was effective in preventing hepatolithiasis after choledochal cyst excisions in open surgeries. Then, we introduced this maneuver into laparoscopic choledochal cyst excisions in 2014 and performed routine resections since then. The aim of this study was to show the feasibility of this method in laparoscopic surgery. METHODS: We retrospectively reviewed the demographics and outcomes of patients who underwent laparoscopic choledochal cyst excisions at our hospital between January 2014 and December 2017. The patients who underwent surgical treatment for IHBDS-causing membrane or septum were compared with those who did not undergo the procedure. The outcomes of the patients with IHBDS were also compared between patients who were ≥ 3 years of age and those < 3 years at operation. RESULTS: Seventeen of 35 patients underwent laparoscopic resection of IHBDS-causing membrane or septum. There were no complications related to the procedure although the operative time and intraoperative bleeding amount increased in the patients with IHBDS who were ≥ 3 years of age. CONCLUSIONS: Meticulous probing and excision of the IHBDS-causing membrane or septum is safe and feasible during laparoscopic choledochal cyst excision.

    DOI: 10.1007/s00383-018-4320-7

    Web of Science

    PubMed

  136. The impact of body weight on stapled anastomosis in pediatric patients. Reviewed International journal

    Hizuru Amano, Yujiro Tanaka, Takahisa Tainaka, Akinari Hinoki, Hiroshi Kawashima, Tomo Kakihara, Kaori Morita, Hiroo Uchida

    Journal of pediatric surgery   Vol. 53 ( 10 ) page: 2036 - 2040   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: The purpose of this study is to clarify the impact of body weight on outcomes of stapled anastomosis in pediatric patients. METHODS: A total of 253 pediatric patients who underwent intestinal anastomosis were classified according to body weight (<3.5 kg: light group, ≥3.5 kg: heavy group), and clinical outcomes of stapled and hand-sewn anastomoses were compared. RESULTS: The light and heavy groups included 77 (stapled: n = 13, hand-sewn: n = 64) and 176 (stapled: n = 58, hand-sewn: n = 118) patients, respectively. In both groups, stapled anastomosis was associated with reduced time to initial oral feeding (light group: 4 vs. 7 days, p = 0.006; heavy group: 3 vs. 5 days, p < 0.001) and full feeding (light group: 12 vs. 16 days, p = 0.026; heavy group: 7 vs. 9 days, p = 0.001), whereas its complication rate was not significantly different from that of hand-sewn anastomosis (light group: 30.8 vs. 12.5%, p = 0.112; heavy group: 3.4 vs. 2.5%, p = 0.665). In patients who underwent stapled anastomosis, the complication rate was significantly higher in the light group (30.8 vs. 3.4%, p = 0.009), with two cases of volvulus related to anastomotic dilatation. CONCLUSIONS: Stapled anastomosis is an effective procedure facilitating prompt oral feeding. However, the risk of complications, including volvulus related to anastomotic dilatation, should be considered among patients weighing <3.5 kg. LEVEL OF EVIDENCE: III.

    DOI: 10.1016/j.jpedsurg.2018.04.030

    Web of Science

    PubMed

  137. Single-stage laparoscopic transanal pull-through modified Swenson procedure without leaving a muscular cuff for short- and long-type Hirschsprung disease: a comparative study. Reviewed International journal

    Kazuki Yokota, Hiroo Uchida, Takahisa Tainaka, Yujiro Tanaka, Chiyoe Shirota, Akinari Hinoki, Takazumi Kato, Wataru Sumida, Kazuo Oshima, Kosuke Chiba, Tetsuya Ishimaru, Hiroshi Kawashima

    Pediatric surgery international   Vol. 34 ( 10 ) page: 1105 - 1110   2018.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PURPOSE: The Soave procedure (SO) is performed most commonly for Hirschsprung disease. SO reduces the risk of injury to the pelvic structures; however, a residual aganglionic muscle cuff could interfere with bowel movement and lead to obstructive enterocolitis. The Swenson procedure is considered ideal in terms of peristalsis. Currently, laparoscopic surgery provides better visualization and facilitates precise dissection, possibly leading to feasible performance of the laparoscopic modified Swenson procedure (SW). We present our operative technique and the efficacy of the SW compared with that of SO. METHODS: We retrospectively reviewed the records of 16 and 27 patients who underwent SW and SO, respectively, between 2012 and 2017. RESULTS: Operative time, blood loss, length of stay, and frequency of bowel movements showed no significant difference between the two groups. In the SW group, temporary dysuria occurred in one patient, postoperative enterocolitis in two, wound infection in one, and severe perianal excoriation in four, whereas in the SO group, obstructive symptoms occurred in three patients, small-bowel obstruction in one, and severe perianal excoriation in three. The complications and outcomes were comparable between both groups. CONCLUSION: Laparoscopic SW was safe and feasible for the short-term follow-up outcomes.

    DOI: 10.1007/s00383-018-4318-1

    Web of Science

    PubMed

  138. BESNet: Boundary-enhanced Segmentation of Cells in Histopathological Images

    Hirohisa Oda, Holger Roth, Kosuke Chiba, Jure Sokolic, Takayuki Kitasaka, Masahiro Oda, Akinari Hinoki, Hiroo Uchida, Julia A Schnabel, Kensaku Mori

    MICCAI 2018, LNCS 11071     page: 228-236   2018.9

     More details

    Language:English   Publishing type:Research paper (other academic)  

  139. Automated ganglion cell detection using fully convolutional networks and evaluation under different training losses

    Hirohisa Oda, Kosuke Chiba, Holger R. Roth, Takayuki Kitasaka, Masahiro Oda, Akinari Hinoki, Hiroo Uchida, Kensaku Mori

    International Journal of Computer Assisted Radiology and Surgery   Vol. 13 ( 1 ) page: s104-106   2018.6

     More details

    Language:English   Publishing type:Research paper (other academic)  

  140. Development of multi-lead ECG measurement wear using electrostatic flocking technology Reviewed

    T. Takeshita, M. Yosihda, A. Ouchi, A. Hinoki, H. Uchida, T. Kobayashi

    2018 International Conference on Electronics Packaging and iMAPS All Asia Conference, ICEP-IAAC 2018     page: 145 - 146   2018.6

     More details

    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:Institute of Electrical and Electronics Engineers Inc.  

    We developed textile-based multi-lead ECG measurement wear. The textile-based ECG measurement wear was fabricated by printed electronics and electrostatic flocking technology. We also developed a wireless communication system of multi-lead ECG signals. Moreover, we succeeded to get 18-lead ECG signals around heart using the ECG measurement wear and the wireless measuring system.

    DOI: 10.23919/ICEP.2018.8374690

    Scopus

  141. Novel thoracoscopic navigation surgery for neonatal chylothorax using indocyanine-green fluorescent lymphography. Reviewed International journal

    Ryo Shirotsuki, Hiroo Uchida, Yujiro Tanaka, Chiyoe Shirota, Kazuki Yokota, Naruhiko Murase, Akinari Hinoki, Kazuo Oshima, Kosuke Chiba, Wataru Sumida, Masahiro Hayakawa, Takahisa Tainaka

    Journal of pediatric surgery   Vol. 53 ( 6 ) page: 1246 - 1249   2018.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Postoperative chylothorax after surgery for esophageal atresia/tracheoesophageal fistula (TEF) is a rare but serious complication, especially in neonates. This study aimed to identify the thoracic duct and ligate chylous leakage sites, using thoracoscopic navigation of an indocyanine-green (ICG)-based near-infrared (NIR) fluorescence imaging system. METHODS: From November 2014 to April 2017, thoracoscopic intraoperative ICG-NIR imaging was performed in 10 newborns (11 surgeries) with first TEF operation or with persistent postoperative chylothorax after TEF operation. NIR imaging was performed 1h after an inter-toe injection of ICG. Thoracoscopic ligations against the NIR-detected leakage sites were performed with sutures. RESULTS: The thoracic duct or lymphatic leakage was directly visualized in each patient. In 8 surgeries with first thoracoscopic TEF operation, one case had suspected minor chylous leakage without postoperative chylothorax. Another case with no chylous leakage at the first operation resulted in chylothorax at postoperative day 11. In three neonates with postoperative chylothorax, leakage points were detected near the ablation site of the azygos vein during the first operation. These points were properly ligated, and postoperative chylous leakage ceased with no adverse events. CONCLUSIONS: Thoracoscopic ICG-NIR imaging encourages the repair of refractory chylothorax and seems reliable. LEVEL OF EVIDENCE: IV.

    DOI: 10.1016/j.jpedsurg.2018.01.019

    Web of Science

    PubMed

  142. 特集 小児外科における消化器内視鏡外科手術 胆道閉鎖症に対する腹腔鏡下肝門部空腸吻合術 Reviewed

    内田 広夫, 田中 裕次郎, 田井中 貴久, 城田 千代栄, 住田 亙, 村瀬 成彦

    手術   Vol. 72 ( 6 ) page: 861 - 870   2018.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:金原出版  

    DOI: 10.18888/op.0000000707

    CiNii Research

  143. Clinical, Pathologic, and Genetic Features of Neonatal Dubin-Johnson Syndrome: A Multicenter Study in Japan

    Togawa Takao, Mizuochi Tatsuki, Sugiura Tokio, Kusano Hironori, Tanikawa Ken, Sasaki Takato, Ichinose Fumio, Kagimoto Seiichi, Tainaka Takahisa, Uchida Hiroo, Saitoh Shinji

    JOURNAL OF PEDIATRICS   Vol. 196   page: 161-+   2018.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpeds.2017.12.058

    Web of Science

    PubMed

  144. Evaluation of Surgical Devices Using an Artificial Pediatric Thoracic Model: A Comparison Between Robot-Assisted Thoracoscopic Suturing Versus Conventional Video-Assisted Thoracoscopic Suturing. Reviewed International journal

    Shinya Takazawa, Tetsuya Ishimaru, Kanako Harada, Kyoichi Deie, Akinari Hinoki, Hiroo Uchida, Naohiko Sugita, Mamoru Mitsuishi, Tadashi Iwanaka, Jun Fujishiro

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 28 ( 5 ) page: 622 - 627   2018.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Pediatric robot-assisted surgery is increasingly being performed, but it is difficult to perform this procedure in infants. A pediatric thoracoscopic model of a 1-year-old patient was developed in our previous study, and this model was used to evaluate the use of a surgical robot for infant surgery. METHODS: Eight pediatric surgeons performed an intracorporeal suturing and knot-tying task using the da Vinci Xi Robotic Surgical System. The task completion time, number of needle manipulations, and force applied during suturing of the robot-assisted thoracoscopic surgery (RATS) group were compared with those of the video-assisted thoracoscopic surgery (VATS) group whose data had been collected from the same 8 surgeons in our previous study. RESULTS: The RATS group showed a significantly shorter completion time than the VATS group in the knot-tying phase (P = .016) and in the total phase (P = .0078). The RATS group showed a significantly smaller number of manipulations than the VATS group in the total phase (P = .039). The RATS group showed a significantly smaller pushing force index than the VATS group in the suturing phase (P = .031), knot-tying phase (P = .031), and in the total phase (P = .031). A seventh rib in the model was dislocated in all RATS group cases. CONCLUSIONS: The da Vinci Surgical System might be useful in infants because of fast movement and small pushing force. However, the robotic 8 mm instruments were too large for use in the thoracic cavity of the 1-year-old infant.

    DOI: 10.1089/lap.2017.0307

    Web of Science

    PubMed

  145. Usefulness of fetal magnetic resonance imaging for postnatal management of congenital lung cysts: prediction of probability for emergency surgery. Reviewed International journal

    Chiyoe Shirota, Takahisa Tainaka, Toshiki Nakane, Yujiro Tanaka, Akinari Hinoki, Wataru Sumida, Naruhiko Murase, Kazuo Oshima, Kosuke Chiba, Ryo Shirotsuki, Hiroo Uchida

    BMC pediatrics   Vol. 18 ( 1 ) page: 105 - 105   2018.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    BACKGROUND: Emergency rescue lung resection is rarely performed to treat congenital lung cysts (CLCs) in neonates. Many reports have described fetal CLC treatment; however, prenatal predictors for postnatal respiratory failure have not been characterized. We hypothesized that fetal imaging findings are useful predictors of emergency surgery. METHODS: We retrospectively studied patients with CLC who underwent lung surgery during the neonatal period in our hospital between January 2001 and December 2015. The demographic data, fetal imaging findings, and intra- and postoperative courses of patients who underwent emergency surgery (Em group) were compared with those of patients who received elective surgery, i.e., non-emergency surgery (Ne group). RESULTS: The Em group and Ne group included 7 and 11 patients, respectively. No significant difference was noted in gestational age, time at prenatal diagnosis, birth weight, and body weight at surgery. The volumes of contralateral lung per thoracic volume were significantly smaller in the Em group than in the Ne group (p = 0.0188). Mediastinal compression was more common in the Em group (7/7) than in the Ne group (4/11) (p = 0.0128). CONCLUSIONS: This is the report describing neonatal emergency lobectomy in patients with CLC evaluated by fetal MRI using the lung volume ratio and mediastinal shift. In patients with CLC, mediastinal shift and significant decreases in contralateral lung volumes during the fetal stages are good prenatal predictors of postnatal emergency lung resection.

    DOI: 10.1186/s12887-018-1085-z

    Web of Science

    PubMed

  146. Fabrication of Multi-lead ECG measurement wear using electrostatic flocking technology Reviewed

    Proceedings of JIEP Annual Meeting   Vol. 32 ( 0 ) page: 179 - 180   2018

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japan Institute of Electronics Packaging  

    DOI: 10.11486/ejisso.32.0_179

  147. Idiopathic Omental Torsion Relieved With Conservative Management Reviewed

    Yokota Kazuki, Chiba Kosuke, Uchida Hiroo, Tanaka Yujiro, Tainaka Takahisa, Shirota Chiyoe, Hinoki Akinari, Sumida Wataru, Kato Takazumi, Oshima Kazuo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 54 ( 2 ) page: 302 - 306   2018

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>The patient was a 5-year-old boy who had no medical history. He was referred to us with suspected acute appendicitis and complaints of fever and lower abdominal pain. Although his abdominal pain was intense, rebound tenderness and muscular protection were negative. There were no symptoms of problems in the digestive tract such as vomiting or diarrhea. His blood examination revealed an increase in inflammatory reactions, as indicated by the increased white blood cell count and C-reactive protein levels. Computed tomography (CT) revealed wall thickening of the ascending colon; therefore, we started antibiotic administration after acute enterocolitis was diagnosed. After admission, we performed CT again and found a fatty and dense mass with a swirling structure inside the mass; therefore, we diagnosed the patient as having idiopathic omental torsion. Because the symptoms were relieved, conservative management was continued and the patient was discharged on the fourth day after hospitalization. Omental torsion is a rare condition, particularly seen in children; its classical treatment option is surgery. Although conservative management was successful in this case, there are few reports on it. There are many cases where surgery is performed after an initial diagnosis of acute appendicitis is made owing to the presence of similar symptoms. However, in recent years, because of advances in imaging diagnostic techniques such as CT, more patients are being accurately diagnosed. We believe that if patients are accurately diagnosed, surgery will always be required; however, conservative management is sometimes possible.</p>

    DOI: 10.11164/jjsps.54.2_302

  148. BESNet: Boundary-Enhanced Segmentation of Cells in Histopathological Images Reviewed

    Oda Hirohisa, Roth Holger R., Chiba Kosuke, Sokolic Jure, Kitasaka Takayuki, Oda Masahiro, Hinoki Akinari, Uchida Hiroo, Schnabel Julia A., Mori Kensaku

    MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2018, PT II   Vol. 11071   page: 228 - 236   2018

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/978-3-030-00934-2_26

    Web of Science

    Scopus

  149. The efficacy of resection of intrahepatic bile duct stenosis-causing membrane or septum for preventing hepatolithiasis after choledochal cyst excision. Reviewed

    Tanaka Y, Tainaka T, Sumida W, Shirota C, Hinoki A, Murase N, Oshima K, Shirotsuki R, Chiba K, Uchida H

    Journal of pediatric surgery   Vol. 52 ( 12 ) page: 1930-1933   2017.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2017.08.056

    PubMed

  150. Intralobar pulmonary sequestration expanding toward the contralateral thorax: two case reports. Reviewed

    Amano H, Fujishiro J, Hinoki A, Uchida H

    BMC surgery   Vol. 17 ( 1 ) page: 110   2017.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12893-017-0313-z

    PubMed

  151. Excellent prognosis of patients with intermediate-risk neuroblastoma and residual tumor postchemotherapy. Reviewed

    Amano H, Uchida H, Tanaka Y, Tainaka T, Mori M, Oguma E, Kishimoto H, Kawashima H, Arakawa Y, Hanada R, Koh K

    Journal of pediatric surgery     2017.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2017.10.061

    PubMed

  152. Mesh hiatal reinforcement in laparoscopic Nissen fundoplication for neurologically impaired children is safe and feasible. Reviewed

    Amano H, Tanaka Y, Kawashima H, Deie K, Suzuki K, Fujiogi M, Morita K, Iwanaka T, Uchida H

    Nagoya journal of medical science   Vol. 79 ( 4 ) page: 427-433   2017.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.79.4.427

    PubMed

  153. Comparison of outcomes of thoracoscopic primary repair of gross type C esophageal atresia performed by qualified and non-qualified surgeons. Reviewed

    Tanaka Y, Tainaka T, Sumida W, Shirota C, Murase N, Oshima K, Shirotsuki R, Chiba K, Uchida H

    Pediatric surgery international   Vol. 33 ( 10 ) page: 1081-1086   2017.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-017-4140-1

    PubMed

  154. A Novel Laparoscopic Surgery Model with a Device to Expand the Abdominal Working Space in Rats: The Influence of Pneumoperitoneum and Skin Incision Length on Postoperative Inflammatory Cytokines. Reviewed

    Murase N, Tainaka T, Uchida H, Hinoki A, Shirota C, Yokota K, Oshima K, Shirotsuki R, Chiba K, Tanaka Y

    Journal of investigative surgery : the official journal of the Academy of Surgical Research     page: 1-6   2017.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/08941939.2017.1366603

    PubMed

  155. Review of redo-Kasai portoenterostomy for biliary atresia in the transition to the liver transplantation era. Reviewed

    Sumida W, Uchida H, Tanaka Y, Tainaka T, Shirota C, Murase N, Oshima K, Shirotsuki R, Chiba K

    Nagoya journal of medical science   Vol. 79 ( 3 ) page: 415-420   2017.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.79.3.415

    PubMed

  156. Comparison of single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) and open repair for pediatric inguinal hernia: a single-center retrospective cohort study of 2028 cases. Reviewed

    Amano H, Tanaka Y, Kawashima H, Deie K, Fujiogi M, Suzuki K, Morita K, Iwanaka T, Uchida H

    Surgical endoscopy     2017.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00464-017-5472-6

    PubMed

  157. New Navigation Surgery for Resection of Lymphatic Malformations Using Indocyanine Green Fluorescence Imaging. Reviewed

    Shirota C, Hinoki A, Takahashi M, Tanaka Y, Tainaka T, Sumida W, Murase N, Oshima K, Shirotsuki R, Chiba K, Morimoto Y, Uchida H

    The American journal of case reports   Vol. 18   page: 529-531   2017.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  158. New Navigation Surgery for Resection of Lymphatic Malformations Using Indocyanine Green Fluorescence Imaging

    Shirota Chiyoe, Hinoki Akinari, Takahashi Masataka, Tanaka Yujiro, Tainaka Takahisa, Sumida Wataru, Murase Naruhiko, Oshima Kazuo, Shirotsuki Ryo, Chiba Kosuke, Morimoto Yuji, Uchida Hiroo

    AMERICAN JOURNAL OF CASE REPORTS   Vol. 18   2017.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.12659/AJCR.903465

    Web of Science

  159. Laparoscopic resection of neuroblastomas in low- to high-risk patients without image-defined risk factors is safe and feasible. Reviewed

    Shirota C, Tainaka T, Uchida H, Hinoki A, Chiba K, Tanaka Y

    BMC pediatrics   Vol. 17 ( 1 ) page: 71   2017.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12887-017-0826-8

    PubMed

  160. Two-Stage Thoracoscopic Repair of Long-Gap Esophageal Atresia Using Internal Traction Is Safe and Feasible. Reviewed

    Tainaka T, Uchida H, Tanano A, Shirota C, Hinoki A, Murase N, Yokota K, Oshima K, Shirotsuki R, Chiba K, Amano H, Kawashima H, Tanaka Y

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 27 ( 1 ) page: 71-75   2017.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2016.0207

    PubMed

  161. Pure Laparoscopic Partial Hepatectomy for Hepatoblastoma in an Infant: A Case Report Reviewed

    Amano Hizuru, Kawashima Hiroshi, Tanaka Yujiro, Deie Kyoichi, Fujiogi Michimasa, Suzuki Keisuke, Morita Kaori, Iwanaka Tadashi, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 53 ( 5 ) page: 1073 - 1078   2017

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>Reports on laparoscopic hepatectomy for malignant tumors in children are few. We present a case of pure laparoscopic partial hepatectomy for hepatoblastoma. A baby girl with Beckwith-Wiedemann syndrome underwent surgical closure of an omphalocele on the sixth day of life. At 4 months, sonographic screening revealed a liver tumor. The alpha-fetoprotein level was 23,060.69 ng/ml, and contrast-enhanced computed tomography revealed a 3.7-cm mass at the left lateral segment of the liver. A biopsy of the mass confirmed the diagnosis of hepatoblastoma (PRETEXT I). After 4 cycles of cisplatin monotherapy, the size of the tumor decreased to 2.7 cm. Laparoscopic partial hepatectomy was performed when she was 6 months old. An umbilical incision was made in an inverted Y shape, allowing for E-Z Access<sup>TM</sup> with a Lap Protector<sup>TM</sup> insertion through which a 1.2-cm trocar was introduced. Two 5-mm working ports were placed lateral to the rectus muscle of either side immediately superior to the umbilicus. After placing a tape around the porta hepatis for the Pringle maneuver in the case of severe bleeding, intraoperative ultrasonography was performed for the identification of the vascular tree and hepatic and portal veins, and the localization of the tumor for accurate and safe resection. Enseal<sup>®</sup> was used to divide the hepatic parenchyma. Branched vessels and ducts were clipped and transected using Enseal<sup>®</sup>. The surgical specimen was extracted through the umbilical incision without enlarging the incision. The patient had an uncomplicated recovery. No recurrence was observed during a 2-year follow-up.</p>

    DOI: 10.11164/jjsps.53.5_1073

  162. Comparing surgical outcomes of complete thoracoscopic lobectomy for congenital cystic lung disease between neonatal and infantile patients. Reviewed

    Tainaka T, Uchida H, Tanaka Y, Shirota C, Yokota K, Murase N, Oshima K, Shirotsuki R, Chiba K, Hinoki A

    Nagoya journal of medical science   Vol. 78 ( 4 ) page: 447-454   2016.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.78.4.447

    PubMed

  163. Large retroperitoneal immature teratoma leading to renovascular hypertension. Reviewed

    Tainaka T, Ono Y, Yamada Y, Mutoh D, Uchida H

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 58 ( 12 ) page: 1363-1364   2016.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.13040

    PubMed

  164. ◆実践報告 先天性中枢性肺胞低換気症候群に合併したヒルシュスプルング病乳児の作業療法─ストレス反応の軽減と姿勢コントロールの獲得 Reviewed

    吉田 彬人, 辛島 千恵子, 牧田 智, 西川 貴久子, 内田 広夫

    作業療法   Vol. 35 ( 6 ) page: 654 - 661   2016.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:株式会社医学書院  

    DOI: 10.11477/mf.6003200186

    CiNii Research

  165. Risk factors for thoracic and spinal deformities following lung resection in neonates, infants, and children. Reviewed

    Makita S, Kaneko K, Ono Y, Uchida H

    Surgery today     2016.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-016-1434-1

    PubMed

  166. Neonatal Cholestasis in East-Asian patients with Dubin-Johnson Syndrome: Clinical, Pathological and Genetic Features Reviewed International journal

    Takao Togawa, Tokio Sugiura, Tatsuki Mizuochi, Hironori Kusano, Ken Tanikawa, Takahisa Tainaka, Hiroo Uchida, Tomoko Hara, Ryusuke Nambu, Seiichi Kagimoto, Shinji Saitoh

    HEPATOLOGY   Vol. 64   page: 278A - 278A   2016.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY  

    Web of Science

  167. Classification of biliary atresia in the laparoscopic era. Reviewed

    Nakamura H, Murase N, Koga H, Cazares J, Lane GJ, Uchida H, Yamataka A

    Pediatric surgery international     2016.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-016-3973-3

    PubMed

  168. More than one-third of successfully nonoperatively treated patients with complicated appendicitis experienced recurrent appendicitis: Is interval appendectomy necessary? Reviewed

    Tanaka Y, Uchida H, Kawashima H, Fujiogi M, Suzuki K, Takazawa S, Deie K, Amano H, Iwanaka T

    Journal of pediatric surgery     2016.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2016.09.017

    PubMed

  169. Long-term outcomes after revision of Kasai portoenterostomy for biliary atresia. Reviewed

    Shirota C, Uchida H, Ono Y, Murase N, Tainaka T, Yokota K, Oshima K, Shirotsuki R, Hinoki A, Ando H

    Journal of hepato-biliary-pancreatic sciences     2016.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jhbp.395

    PubMed

  170. Steroid pulse therapy prevents restenosis following balloon dilatation for esophageal stricture. Reviewed

    Yokota K, Uchida H, Tanano A, Shirota C, Tainaka T, Hinoki A, Murase N, Oshima K, Shirotsuki R, Chiba K

    Pediatric surgery international   Vol. 32 ( 9 ) page: 875-9   2016.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-016-3939-5

    PubMed

  171. Contraindications and image-defined risk factors in laparoscopic resection of abdominal neuroblastoma. Reviewed

    Tanaka Y, Kawashima H, Mori M, Fujiogi M, Suzuki K, Amano H, Morita K, Arakawa Y, Koh K, Oguma E, Iwanaka T, Uchida H

    Pediatric surgery international   Vol. 32 ( 9 ) page: 845-50   2016.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-016-3932-z

    PubMed

  172. Laparoscopic side-to-side pancreaticojejunostomy for chronic pancreatitis in children. Reviewed

    Deie K, Uchida H, Kawashima H, Tanaka Y, Fujiogi M, Amano H, Murase N, Tainaka T

    Journal of minimal access surgery     2016.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4103/0972-9941.182655

    PubMed

  173. Left thoracoscopic two-stage repair of tracheoesophageal fistula with a right aortic arch and a vascular ring. Reviewed

    Oshima K, Uchida H, Tainaka T, Tanano A, Shirota C, Yokota K, Murase N, Shirotsuki R, Chiba K, Hinoki A

    Journal of minimal access surgery     2016.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4103/0972-9941.181771

    PubMed

  174. Cytomegalovirus (CMV) Monitoring After Liver Transplantation: Comparison of CMV Pp65 Antigenemia Assay with Real-Time PCR Calibrated to WHO International Standard. Reviewed

    Kamei H, Ito Y, Onishi Y, Suzuki M, Imai H, Kurata N, Hori T, Tainaka T, Uchida H, Ogura Y

    Annals of transplantation   Vol. 21   page: 131-6   2016.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  175. A feasibility of single-incision laparoscopic percutaneous extraperitoneal closure for treatment of incarcerated inguinal hernia in children: our preliminary outcome and review of the literature. Reviewed

    Murase N, Uchida H, Seki T, Hiramatsu K

    Nagoya journal of medical science   Vol. 78 ( 1 ) page: 19-25   2016.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  176. A feasibility of single-incision laparoscopic percutaneous extraperitoneal closure for treatment of incarcerated inguinal hernia in children: our preliminary outcome and review of the literature Reviewed

    Naruhiko Murase, Hiroo Uchida, Takashi Seki, Kiyoshi Hiramatsu

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 78 ( 1 ) page: 19 - 25   2016.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NAGOYA UNIV, SCH MED  

    The purpose of this study is to examine the feasibility of single-incision laparoscopic percutaneous extraperitoneal closure (LPEC) for incarcerated inguinal hernia (IIH) repair. 6 single-incision LPEC procedures were performed for IIH repair and 60 procedures were performed for reducible inguinal hernia (RIH) in the same period of time in one hospital. The laparoscope and one pair of grasping forceps were placed through the same umbilical incision. In IIH repair, the herniated organ was gently pulled using the grasping forceps with external manual pressure. If it was difficult to reduce the herniated organ with one pair of forceps, another pair of forceps were inserted through a multi-channel port without extending the umbilical incidion. Using the LPEC needle, the hernia orifice was closed extraperitoneally. We performed a retrospective analysis to compare the outcomes of single-incision LPEC for IIH repair or reducible inguinal hernia. All procedures were completed by single-incision without open conversion. A multi-channel port with another pair of forceps was needed in three cases. The operation time and the length of stay were significantly longer with IIH repair than with RIH repair. There were no major complications and there was no evidence of early recurrence in any patient. In conclusion, single-incision LPEC with a multi-channel port is feasible and safe for IIH repair.

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  177. A feasibility of single-incision laparoscopic percutaneous extraperitoneal closure for treatment of incarcerated inguinal hernia in children: our preliminary outcome and review of the literature Reviewed

    Murase Naruhiko, Uchida Hiroo, Seki Takashi, Hiramatsu Kiyoshi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 78 ( 1 ) page: 19 - 25   2016.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  178. Operative procedures of single-incision laparoscopic repair of pediatric epigastric hernia have become simple and feasible with the use of a novel suture-assisting needle Reviewed International journal

    Kyoichi Deie, Hiroo Uchida, Hiroshi Kawashima, Yujiro Tanaka, Hizuru Amano, Naruhiko Murase, Takahisa Tainaka

    Journal of Pediatric Surgery Case Reports   Vol. 4   page: 22 - 26   2016.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier Inc.  

    We describe a simple and feasible procedure for single-incision laparoscopic repair of a pediatric epigastric hernia using a novel suture-assisting needle. A multichannel port was inserted through the umbilical vertical incision. After the orifice of the hernia was identified, a suture-assisting needle, which can hold a suture at its tip, with a 2-0 thread was pierced through the skin into one side of the rectus muscle sheath into the abdominal cavity. Next, after releasing the thread, the needle was pulled out to the subcutis and pierced through another side of the rectus muscle sheath. The needle, grasping the thread again, was subsequently pulled out through the abdominal wall outside, and the thread was tied extracorporeally. This knot was buried subcutaneously. Operative procedures of single-incision laparoscopic repair of an epigastric hernia have become simple and feasible with the use of a novel suture-assisting needle with an excellent cosmetic result.

    DOI: 10.1016/j.epsc.2015.11.010

    Web of Science

    Scopus

  179. A Case of Fibrolamellar Hepatocellular Carcinoma Treated by Gemcitabine/Oxaliplatin Chemotherapy (GEMOX Chemotherapy) Preoperatively and Postoperatively Reviewed

    Makita Satoshi, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 52 ( 6 ) page: 1251 - 1255   2016

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    <p>Fibrolamellar hepatocellular carcinoma (FLHCC) is rare in children. In Japan, there are only six reports of children with FLHCC. We report a case of FLHCC aggressively treated by surgery and chemotherapy. A 12-year-old girl with liver tumor was admitted to our hospital for treatment. FLHCC with lymph node metastases was suspected from various imaging studies and definitively diagnosed as FLHCC by laparotomy biopsy. One cycle of gemcitabine/oxaliplatin (GEMOX) chemotherapy was administered preoperatively because of multiple lymph node metastases. After chemotherapy, her PIVKA-II level decreased but there was no reduction in tumor size. As a result, left hepatectomy and lymphadenectomy were performed. GEMOX chemotherapy was administered as a postoperative adjuvant. After 2 cycles of GEMOX chemotherapy, she developed adhesive ileus and adhesiotomy was performed. Ten cycles of GEMOX chemotherapy were administered after adhesiotomy, and then she was discharged. To date, 3 years after surgery, there is no evidence of recurrence.</p>

    DOI: 10.11164/jjsps.52.6_1251

  180. Emergency hepatectomy for hepatic arteriovenous malformation combined with pulmonary hypertension in an infant Reviewed International journal

    Naruhiko Murase, Hiroo Uchida, Akihide Tanano, Chiyoe Shirota, Akinari Hinoki, Takahisa Tainaka, Kazuki Yokota, Kazuo Oshima, Ryo Shirotsuki

    Journal of Pediatric Surgery Case Reports   Vol. 3 ( 12 ) page: 534 - 536   2015.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier Inc.  

    Patients with hepatic arteriovenous malformations rarely present with pulmonary hypertension. We report the case of a 3-month-old boy who developed severe pulmonary hypertension due to a hepatic arteriovenous malformation. The use of pulmonary vasodilators to treat the patient's pulmonary hypertension worsened his high-output heart failure. This is the first case in which emergency hepatectomy rescued a patient with hepatic arteriovenous malformations who developed pulmonary hypertension.

    DOI: 10.1016/j.epsc.2015.10.017

    Web of Science

    Scopus

  181. Laparoscopic-assisted pancreaticoduodenectomy in a child with gastrinoma. Reviewed

    Murase N, Uchida H, Tainaka T, Kawashima H, Tanaka Y, Amano H, Kishimoto H

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 57 ( 6 ) page: 1196-8   2015.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.12715

    PubMed

  182. Pediatric Surgery. Reviewed

    Iwanaka T, Yamataka A, Uemura S, Okuyama H, Segawa O, Nio M, Yoshizawa J, Yagi M, Ieiri S, Uchida H, Koga H, Sato M, Soh H, Take H, Hirose R, Fukuzawa H, Mizuno M, Watanabe T

    Asian journal of endoscopic surgery   Vol. 8 ( 4 ) page: 390-407   2015.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ases.12263

    PubMed

  183. An Easy and Safe Technique for Laparoscopic Pyloromyotomy: Using a Vascular Clamp for Stabilization of the Pylorus. Reviewed

    Fujiogi M, Tanaka Y, Kawashima H, Toma M, Suzuki K, Amano H, Morita K, Uchida H, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A     2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2015.0109

    PubMed

  184. Influence of surgical intervention on neurodevelopmental outcome in infants with focal intestinal perforation. Reviewed

    Tanaka Y, Uchida H, Kawashima H, Sato K, Takazawa S, Deie K, Masuko T, Kanno K, Shimizu M

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 57 ( 4 ) page: 687-9   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.12599

    PubMed

  185. Accessory scrotum with perineal lipoma diagnosed prenatally: case report and review of the literature. Reviewed

    Murase N, Uchida H, Hiramatsu K

    Nagoya journal of medical science   Vol. 77 ( 3 ) page: 501-6   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  186. A new modification of laparoscopic percutaneous extraperitoneal closure procedure for repairing pediatric femoral hernias involving a special needle and a wire loop. Reviewed

    Tainaka T, Uchida H, Ono Y, Tanano A, Shirota C, Yokota K, Murase N, Makita S, Shirotsuki R

    Nagoya journal of medical science   Vol. 77 ( 3 ) page: 531-5   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  187. Accessory scrotum with perineal lipoma diagnosed prenatally: case report and review of the literature Reviewed

    Naruhiko Murase, Hiroo Uchida, Kiyoshi Hiramatsu

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 77 ( 3 ) page: 501 - 506   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NAGOYA UNIV, SCH MED  

    We report a case of accessory scrotum (AS) in the perineal region with peduncular lipoma, diagnosed prenatally. A male fetus of 31 weeks' gestation was referred to our department with a perineal mass. Prenatal ultrasonography and magnetic resonance imaging showed a mass of 1.0 x 1.2 cm located posterior to the scrotum. No other abnormalities were noted during pregnancy. The patient was delivered vaginally at 38 weeks of gestation. On physical examination, a soft peduncular mass with a rugged and pigmented swelling was located between the normally developed scrotum and the anus. There were no specific symptoms or any other associated congenital anomalies. We completely excised the mass at one month of age. A histological examination revealed lipoma, with tissue suggestive of scrotum, so a definite diagnosis of AS was made. AS is a rare congenital anomaly of the scrotum. We review the literature.

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  188. A new modification of laparoscopic percutaneous extraperitoneal closure procedure for repairing pediatric femoral hernias involving a special needle and a wire loop Reviewed

    Takahisa Tainaka, Hiroo Uchida, Yasuyuki Ono, Akihide Tanano, Chiyoe Shirota, Kazuki Yokota, Naruhiko Murase, Satoshi Makita, Ryo Shirotsuki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 77 ( 3 ) page: 531 - 535   2015.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NAGOYA UNIV, SCH MED  

    Femoral hernias are relatively rare in children, and more than half of pediatric femoral hernias are misdiagnosed. A 3-year-old boy was treated for an indirect inguinal hernia at the age of 2, but he exhibited an inguinal bulge one month after the operation. He underwent laparoscopy, and a right femoral hernia was detected. The femoral hernia was laparoscopically repaired via two small incisions: a 1.0-cm umbilical incision for a 3-mm 30 degrees laparoscope and 3-mm grasping forceps and a 5-mm right lateral incision for 3-mm grasping forceps. After the hernia sac had been reflected into the abdominal cavity and resected, the iliopubic tract was sutured to Cooper's ligament using a laparoscopic percutaneous extracorporeal closure (LPEC) needle and 2-0 non-absorbable sutures. Laparoscopy enables the accurate diagnosis of rare and often missed pediatric femoral hernias. Our laparoscopic technique for treating femoral hernias is easy and effective. Although these early results are encouraging, more cases involving longer follow-up periods should be accumulated to confirm the efficacy of our technique.

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  189. Long-term outcomes of operative versus nonoperative treatment for uncomplicated appendicitis. Reviewed

    Tanaka Y, Uchida H, Kawashima H, Fujiogi M, Takazawa S, Deie K, Amano H

    Journal of pediatric surgery     2015.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2015.07.008

    PubMed

  190. Prophylactic effect of H2 blocker for anastomotic stricture after esophageal atresia repair. Reviewed

    Murase N, Uchida H, Kaneko K, Ono Y, Makita S, Yokota K

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 57 ( 3 ) page: 461-4   2015.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ped.12529

    PubMed

  191. Current Practice and Outcomes of Thoracoscopic Esophageal Atresia and Tracheoesophageal Fistula Repair: A Multi-institutional Analysis in Japan. Reviewed

    Okuyama H, Koga H, Ishimaru T, Kawashima H, Yamataka A, Urushihara N, Segawa O, Uchida H, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 25 ( 5 ) page: 441-4   2015.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2014.0250

    PubMed

  192. Effectiveness and safety of immunization with live-attenuated and inactivated vaccines for pediatric liver transplantation recipients. Reviewed

    Kawano Y, Suzuki M, Kawada J, Kimura H, Kamei H, Ohnishi Y, Ono Y, Uchida H, Ogura Y, Ito Y

    Vaccine   Vol. 33 ( 12 ) page: 1440-5   2015.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.vaccine.2015.01.075

    PubMed

  193. Laparoscopic ligation of varicocele testis in children:TANKO operation Reviewed

      Vol. 69 ( 2 ) page: 179 - 185   2015.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.11477/mf.1413205164

    CiNii Research

  194. Laparoscopic partial gastrectomy of a huge gastric duplication cyst in an infant. Reviewed

    Takazawa S, Uchida H, Kawashima H, Tanaka Y, Sato K, Jimbo T, Iwanaka T

    Nagoya journal of medical science   Vol. 77 ( 1-2 ) page: 291-6   2015.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  195. LAPAROSCOPIC PARTIAL GASTRECTOMY OF A HUGE GASTRIC DUPLICATION CYST IN AN INFANT Reviewed

    Shinya Takazawa, Hiroo Uchida, Hiroshi Kawashima, Yujiro Tanaka, Kaori Sato, Takahiro Jimbo, Tadashi Iwanaka

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 77 ( 1-2 ) page: 291 - 296   2015.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NAGOYA UNIV, SCH MED  

    Gastric duplication cyst is a rare anomaly, and most cases are recognized during childhood. Recently, several pediatric cases with small gastric duplication cysts treated by laparoscopic resection have been reported. Here, we describe an infant in whom we successfully performed laparoscopic partial gastrectomy for the treatment of a huge gastric duplication cyst. To the best of our knowledge, this is the largest gastric duplication cyst treated by laparoscopic surgery among infants. We introduce our procedure and some tips.

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  196. The umbilical Benz incision for reduced port surgery in pediatric patients. Reviewed

    Amano H, Uchida H, Kawashima H, Deie K, Murase N, Makita S, Yokota K, Tanaka Y

    JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons   Vol. 19 ( 1 ) page: e2014.00238   2015.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4293/JSLS.2014.00238

    PubMed

  197. Initial treatment of septated parapneumonic empyema with drainage plus fibrinolytic agents is equally effective as video-assisted thoracoscopic surgery, and is suitable as first-line therapy. Reviewed

    Shirota C, Uchida H

    Translational pediatrics   Vol. 4 ( 1 ) page: 41-4   2015.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3978/j.issn.2224-4336.2015.02.01

    PubMed

  198. Laparoendoscopic-assisted Single-site Surgery of an Ileal Duplication Diagnosed Prenatally as an Intraabdominal Cyst Reviewed

    MURASE Naruhiko, UCHIDA Hiroo, HIRAMATSU Kiyoshi, AMEMIYA Takeshi, SEKI Takashi, ARAI Toshiyuki

    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)   Vol. 76 ( 3 ) page: 529 - 533   2015

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Surgical Association  

    A baby girl delivered at the gestational age of 38 week's was referred to our department because of an intraabdominal cyst diagnosed prenatally. There were no specific symptoms after birth. USG revealed a cyst-like structure with gut signature, and CT showed a cystic mass in the abdomen containing air. A preoperative diagnosis of duplication of the alimentary tract or Meckel's diverticulum was made, and a laparoendoscopic single-site surgery was performed when the baby girl was ten months old. An inverted Y-shaped incision was made at the umbilicus, and laparoscopic exploration revealed a cystic mass sharing a common wall and blood supply with the ileum on the mesenteric side. We exteriorized the duplication cyst with normal ileum from the umbilical incision, and performed resection of the segment of the small bowel including the cystic mass. Histopathology revealed that the ileal duplication cyst was lined with gastric epithelium. The postoperative course was uneventful.

    DOI: 10.3919/jjsa.76.529

  199. A New Era of Laparoscopic Revision of Kasai Portoenterostomy for the Treatment of Biliary Atresia. Reviewed

    Murase N, Uchida H, Ono Y, Tainaka T, Yokota K, Tanano A, Shirota C, Shirotsuki R

    BioMed research international   Vol. 2015   page: 173014   2015

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2015/173014

    PubMed

  200. Laparoscopic ligation of varicocele testis in children: Tanko operation Reviewed International journal

    Kawashima H, Tada M, Sato A, Hori Y, Funakoshi D, Uchida H

    Japanese Journal of Clinical Urology   Vol. 69 ( 2 ) page: 179 - 185   2015

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  201. Laparoscopic partial nephrectomy for the treatment of large cystic nephroma in children. Reviewed

    Tanaka Y, Uchida H, Kawashima H, Masuko T, Takazawa S, Deie K, Amano H, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 24 ( 12 ) page: 901-6   2014.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2014.0222

    PubMed

  202. Surgical complications, especially gastroesophageal reflux disease, intestinal adhesion obstruction, and diaphragmatic hernia recurrence, are major sequelae in survivors of congenital diaphragmatic hernia. Reviewed

    Yokota K, Uchida H, Kaneko K, Ono Y, Murase N, Makita S, Hayakawa M

    Pediatric surgery international   Vol. 30 ( 9 ) page: 895-9   2014.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-014-3575-x

    PubMed

  203. Urethroscopic holmium: YAG laser ablation for acquired posterior urethral diverticulum after repair of anorectal malformations. Reviewed

    Takazawa S, Uchida H, Kawashima H, Tanaka Y, Masuko T, Deie K, Amano H, Kobayashi K, Tada M, Iwanaka T

    Pediatric surgery international   Vol. 30 ( 9 ) page: 945-9   2014.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-014-3569-8

    PubMed

  204. Full-thickness small intestine necrosis with midgut volvulus, distributed in a patchy fashion, is reversible with moderate blood flow: resumption of normal function to non-viable intestine. Reviewed

    Amano H, Uchida H, Kawashima H, Tanaka Y, Kishimoto H

    Nagoya journal of medical science   Vol. 76 ( 3-4 ) page: 375-80   2014.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  205. Massive hemorrhage after Kasai portoenterostomy in a patient with a congenital extrahepatic portosystemic shunt, malrotation and a double aortic arch: report of a case. Reviewed

    Takazawa S, Uchida H, Kawashima H, Tanaka Y, Sato K, Jimbo T, Deie K, Koiwai K, Nomura K, Iwanaka T

    Surgery today   Vol. 44 ( 8 ) page: 1561-4   2014.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-013-0605-6

    PubMed

  206. FULL-THICKNESS SMALL INTESTINE NECROSIS WITH MIDGUT VOLVULUS, DISTRIBUTED IN A PATCHY FASHION, IS REVERSIBLE WITH MODERATE BLOOD FLOW: RESUMPTION OF NORMAL FUNCTION TO NON-VIABLE INTESTINE Reviewed

    Hizuru Amano, Hiroo Uchida, Hiroshi Kawashima, Yujiro Tanaka, Hiroshi Kishimoto

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 76 ( 3-4 ) page: 375 - 380   2014.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NAGOYA UNIV, SCH MED  

    Midgut volvulus is a highly life-threatening condition that carries a high risk of short gut syndrome. We report a case of catastrophic neonatal midgut volvulus in which second-look laparotomy revealed apparently non-viable remnant small intestine but with a moderate blood supply. Full-thickness small intestine necrosis was distributed in a patchy fashion, with non-viable and necrotic areas distributed so widely that no portion of the intestine could be resected. A section of full-thickness necrotic intestine preserved at surgery was able to regenerate, and normal function was restored over a period of 1 month. This case indicated that intestinal resumption may be dependent on blood flow. Even when intestinal viability is questionable, preservation enables the chance of regeneration if moderate blood flow is present.

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  207. OP-052-7 当施設における小児膵SPT(Solid pseudopapillary tumor)の治療経験(OP-052 膵 IPMN・その他,一般演題,第114回日本外科学会定期学術集会) Reviewed

    牧田 智, 金子 健一朗, 小野 靖之, 横田 一樹, 村瀬 成彦, 内田 広夫

    日本外科学会雑誌   Vol. 115 ( 2 ) page: 408   2014.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:一般社団法人日本外科学会  

    CiNii Research

  208. 【直腸肛門奇形術後遠隔期の評価と再手術】 遺残瘻孔の嚢胞化に対する再手術

    高澤 慎也, 内田 広夫

    小児外科   Vol. 46 ( 1 ) page: 31 - 34   2014.1

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

  209. Thoracoscopic Resection of an Intralobar Pulmonary Sequestration in a Neonate With Heart Failure Reviewed

    Murase Naruhiko, Kaneko Kenichiro, Ono Yasuyuki, Yokota Kazuki, Makita Satoshi, Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 50 ( 5 ) page: 946 - 949   2014

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    High-output heart failure in a neonate due to pulmonary sequestration is rare. We report a case of neonatal heart failure relieved with thoracoscopic resection of an intralobar pulmonary sequestration. A male neonate of 39-week gestational age presented with respiratory distress, chest X-ray and echocardiography revealed high-output heart failure. A computed tomography showed a left lower pulmonary sequestration with venous drainage into the azygos system. Preoperative diagnosis is an extralobar pulmonary sequestration, and high-output heart failure is caused by arteriovenous shunt in the pulmonary sequestration. We intervened with thoracoscopic resection on day-of-life 21. Intraoperative diagnosis is an intralobar pulmonary sequestration. Postoperative course was uneventful, and the patient was discharged on postoperative day 20 without any sign of heart failure.

    DOI: 10.11164/jjsps.50.5_946

  210. NOTES for Surgical Treatment of Long-Segment Hirschsprung's Disease: Report of Three Cases Reviewed

    Li, N; Zhang, W; Yu, DH; Sun, XY; Wei, MF; Weng, YZ; Feng, JX

    JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES   Vol. 23 ( 12 ) page: 1020 - 1023   2013.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2013.0180

    Web of Science

    PubMed

  211. Multicenter retrospective comparative study of laparoscopically assisted and conventional anorectoplasty for male infants with rectoprostatic urethral fistula Reviewed

    Yamataka Atsuyuki, Morikawa Yasuhide, Yagi Makoto, Kimura Osamu, Kuroda Tatsuo, Ueno Shigeru, Iwanaka Tadashi, Iwai Jun, Zaizen Yoshio, Koga Hiroyuki, Shimono Ryuichi, Yagi Makoto, Kimura Osamu, Kubota Masayuki, Murase Naruhiko, Kanamori Yutaka, Tanaka Hideaki, Takahashi Masataka, Ikeda Taro, Kubota Akio, Nara Keigo, Satoh Kaori, Amano Hizuru, Takazawa Shinya, Tanaka Yujiro, Uchida Hiroo, Kawashima Hiroshi, Jimbo Takahiro, Fukumoto Kohji, Ueno Shigeru, Ishimaru Tetsuya

    JOURNAL OF PEDIATRIC SURGERY   Vol. 48 ( 12 ) page: 2383-2388   2013.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2013.08.010

    Web of Science

  212. Laparoscopic excision of urachal remnants is a safe and effective alternative to open surgery in children. Reviewed

    Masuko T, Uchida H, Kawashima H, Tanaka Y, Deie K, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 23 ( 12 ) page: 1016-9   2013.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2013.0127

    PubMed

  213. External stabilization for severe tracheobronchomalacia using separated ring-reinforced ePTFE grafts is effective and safe on a long-term basis. Reviewed

    Takazawa S, Uchida H, Kawashima H, Tanaka Y, Masuko T, Deie K, Nagase Y, Iwanaka T

    Pediatric surgery international   Vol. 29 ( 11 ) page: 1165-9   2013.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-013-3383-8

    PubMed

  214. Single-incision laparoscopic-assisted appendectomy in children: exteriorization of the appendix is a key component of a simple and cost-effective surgical technique. Reviewed

    Deie K, Uchida H, Kawashima H, Tanaka Y, Masuko T, Takazawa S

    Pediatric surgery international   Vol. 29 ( 11 ) page: 1187-91   2013.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-013-3373-x

    PubMed

  215. Complete thoracoscopic versus video-assisted thoracoscopic resection of congenital lung lesions. Reviewed

    Tanaka Y, Uchida H, Kawashima H, Sato K, Takazawa S, Masuko T, Deie K, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 23 ( 8 ) page: 719-22   2013.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2013.0110

    PubMed

  216. Successful two-stage thoracoscopic repair of long-gap esophageal atresia using simple internal traction and delayed primary anastomosis in a neonate: report of a case. Reviewed

    Tanaka Y, Uchida H, Kawashima H, Sato K, Takazawa S, Jimbo T, Iwanaka T

    Surgery today   Vol. 43 ( 8 ) page: 906-9   2013.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-012-0426-z

    PubMed

  217. Development of a needle driver with multiple degrees of freedom for neonatal laparoscopic surgery. Reviewed

    Ishimaru T, Takazawa S, Uchida H, Kawashima H, Fujii M, Harada K, Sugita N, Mitsuishi M, Iwanaka T

    Journal of laparoendoscopic & advanced surgical techniques. Part A   Vol. 23 ( 7 ) page: 644-8   2013.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/lap.2013.0130

    PubMed

  218. Long-term survivor of relapsed stage IV malignant rhabdoid tumor of the kidney Reviewed

    Kato Motohiro, Koh Katsuyoshi, Oshima Koichi, Oguma Eiji, Uchida Hiroo, Kishimoto Hiroshi, Kikuchi Akira, Hanada Ryoji

    PEDIATRICS INTERNATIONAL   Vol. 55 ( 2 ) page: 245-248   2013.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/j.1442-200X.2012.03663.x

    Web of Science

  219. Sacrococcygeal yolk sac tumor developing after teratoma: a clinicopathological study of pediatric sacrococcygeal germ cell tumors and a proposal of the pathogenesis of sacrococcygeal yolk sac tumors. Reviewed

    Yoshida M, Matsuoka K, Nakazawa A, Yoshida M, Inoue T, Kishimoto H, Nakayama M, Takaba E, Hamazaki M, Yokoyama S, Horie H, Tanaka M, Gomi K, Ohama Y, Kigasawa H, Kitano Y, Uchida H, Kanamori Y, Iwanaka T, Tanaka Y

    Journal of pediatric surgery   Vol. 48 ( 4 ) page: 776-81   2013.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2012.08.028

    PubMed

  220. Long-term survivor of relapsed stage IV malignant rhabdoid tumor of the kidney. Reviewed

    Kato M, Koh K, Oshima K, Oguma E, Uchida H, Kishimoto H, Kikuchi A, Hanada R

    Pediatrics international : official journal of the Japan Pediatric Society   Vol. 55 ( 2 ) page: 245-8   2013.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi: 10.1111/j.1442-200X.2012.03663.x.

    PubMed

  221. Minimally invasive surgery for pediatric cases of large extraovarian teratoma with considerable solid component Reviewed International journal

    Shinya Takazawa, Hiroo Uchida, Hiroshi Kawashima, Yujiro Tanaka, Kaori Sato, Takahiro Jimbo, Takayuki Masuko, Kyoichi Deie, Tadashi Iwanaka

    Journal of Pediatric Surgery Case Reports   Vol. 1 ( 8 ) page: 226 - 229   2013

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier Inc.  

    Pediatric patients with large extraovarian teratomas with a significant solid component are usually treated using open surgery because the size of the intracorporeal cavity does not facilitate the manipulation of large tumors. Here, we describe the cases of 3 children who underwent minimally invasive surgery for large extraovarian teratomas (diameter &gt
    10 cm), including 2 cases of retroperitoneal teratoma and 1 case of a thoracic teratoma. All tumors had a large amount of sebaceous material that displaced other surrounding organs. Tumor volumes were reduced by intraoperative needle aspiration using a SAND balloon catheter with a double balloon that is designed to minimize the risk of spillage. Intraoperative needle aspiration of cystic content can provide sufficient working space and facilitates safe separation of the major vessels from the tumor. Treatment of large extraovarian teratomas by minimally invasive surgery involving skin incisions that result in a less noticeable scar, such as a Pfannenstiel incision or axillary incision, can achieve improved cosmetic outcomes. © 2013 The Authors.

    DOI: 10.1016/j.epsc.2013.07.003

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  222. 肺転移を認めるStage IV肝芽腫の1例 Reviewed

    森 麻希子, 康 勝好, 磯部 清孝, 秋山 康介, 安井 直子, 関 正史, 高橋 寛吉, 加藤 元博, 田中 裕次郎, 内田 広夫, 小熊 栄二, 岸本 宏志, 花田 良二

    日本小児血液・がん学会雑誌   Vol. 49 ( 3 ) page: 410 - 410   2012.10

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本小児血液・がん学会  

  223. Stapled intestinal anastomosis is a simple and reliable method for management of intestinal caliber discrepancy in children. Reviewed

    Sato K, Uchida H, Tanaka Y, Takazawa S, Jimbo T, Deie K

    Pediatric surgery international   Vol. 28 ( 9 ) page: 893-8   2012.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-012-3146-y

    PubMed

  224. 【虫垂炎-最近の話題】 急性虫垂炎の術式選択 腫瘤形成性虫垂炎に対するinterval appendectomy

    高澤 慎也, 内田 広夫

    小児外科   Vol. 44 ( 5 ) page: 451 - 454   2012.5

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

  225. 【小児消化管内視鏡:診断と治療の最前線】 小児膵疾患に対する内視鏡的経乳頭的治療

    高澤 慎也, 内田 広夫, 糸井 隆夫

    小児外科   Vol. 44 ( 3 ) page: 287 - 291   2012.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

  226. Differences in the characteristics and management of pyriform sinus fistula between neonates and young children. Reviewed

    Amano H, Uchida H, Sato K, Kawashima H, Tanaka Y, Takazawa S, Jimbo T

    Pediatric surgery international   Vol. 28 ( 1 ) page: 15-20   2012.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-011-3008-z

    PubMed

  227. 22. 絞扼性イレウスによりY脚消失,および短腸症候群となった総胆管拡張症術後の1例の治療戦略(一般演題,第47回日本小児外科学会関東甲信越地方会) Reviewed

    益子 貴行, 内田 広夫, 川嶋 寛, 田中 裕次郎, 出家 亨一

    日本小児外科学会雑誌   Vol. 48 ( 7 ) page: 1078   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.7_1078_3

  228. WS2-10 単孔式腹腔鏡下鼠径ヘルニア根治術は鼠径ヘルニア根治術の標準術式となりうるか : 手術習熟度からみた考察(ワークショップ2 手術の教育) Reviewed

    内田 広夫, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 出家 亨一, 小岩井 和樹, 多田 実, 小林 堅一郎, 益子 貴行

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 400   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_400_2

  229. WS2-08 内視鏡手術手技トレーニングシステムの構築(ワークショップ2 手術の教育) Reviewed

    高澤 慎也, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 益子 貴行, 神保 教広, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 399   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_399_2

  230. V2-02 左肺底動脈大動脈起始症に対する胸腔鏡手術(ビデオセッション2 食道・肺) Reviewed

    田中 裕次郎, 内田 広夫, 佐藤 かおり, 高澤 慎也, 神保 教広, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 445   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_445_2

  231. V1-02 腎孟尿管移行部狭窄症に対する腹腔鏡下腎孟形成術 : laparoscopic Anderson-Hynes dismembered pyeloplasty(ビデオセッション1 泌尿器他) Reviewed

    内田 広夫, 多田 実, 川島 寛, 益子 貴行, 小林 堅一郎, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 443   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_443_2

  232. V1-01 大動脈食道瘻により大量吐血した,胆道閉鎖症,門脈大循環シャントType 1を合併した重複大動脈弓症の一例(ビデオセッション1 泌尿器他) Reviewed

    高澤 慎也, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 神保 教広, 出家 亨一, 小岩井 和樹, 宮林 寛, 菅野 啓一, 清水 正樹, 野村 耕司

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 443   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_443_1

  233. P9-05 骨髄移植後のStage IV神経芽細胞腫に対する腹腔鏡下摘出術(ポスターセッション9 腫瘍1) Reviewed

    神保 教広, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 539   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_539_2

  234. P43-05 虫垂炎に対する単孔式腹腔鏡補助下虫垂切除術 : 多孔式腹腔鏡下虫垂切除より,簡便で経済的な術式を目指して(ポスターセッション43 虫垂炎) Reviewed

    出家 亨一, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 668   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_668_1

  235. P23-04 当センターにおける極低出生体重児の外科手術とその予後(ポスターセッション23 新生児) Reviewed

    田中 裕次郎, 内田 広夫, 佐藤 かおり, 高澤 慎也, 神保 教広, 出家 亨一, 小岩井 和樹, 清水 正樹, 菅野 啓一

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 596   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_596_2

  236. P19-04 完全胸腔鏡下肺葉切除術の実際 : 胸腔鏡補助下肺葉切除術との比較(ポスターセッション19 循環呼吸器外科の最前線1) Reviewed

    高澤 慎也, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 神保 教広, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 585   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_585_2

  237. O9-02 手術歴のない腸閉塞症患児に対する治療戦略(一般口演9 腸管) Reviewed

    神保 教広, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 出家 亨一, 小岩井 和樹

    日本小児外科学会雑誌   Vol. 48 ( 3 ) page: 505   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.3_505_2

  238. 32. 胃軸捻の原因となった遊走脾に対して腹腔鏡下脾固定術(腹膜外ポケット法)を行った1例(一般演題,第46回日本小児外科学会関東甲信越地方会) Reviewed

    高澤 慎也, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 神保 教広

    日本小児外科学会雑誌   Vol. 48 ( 1 ) page: 143 - 143   2012

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.48.1_143_2

  239. 小児に対する腹腔鏡下腎摘除術

    高澤 慎也, 多田 実, 小林 堅一郎, 益子 貴行, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 神保 教広, 宮川 亨平, 中村 譲

    埼玉県医学会雑誌   Vol. 46 ( 1 ) page: 55 - 57   2011.10

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:埼玉県医学会  

    腹腔鏡下腎摘除術を施行した小児患者16例(男児4例、女児12例、中央値5歳)の成績を報告した。男児の基礎疾患はそれぞれ精嚢腺嚢胞と同側単純性尿管瘤合併、膀胱尿管逆流症と腎盂尿管移行部狭窄合併、単純性尿管瘤とMCDK合併、尿管異所開口であった。女児は全例尿管異所開口で、9例は開口部が同定不能であった。手術は患側を上にした半側臥位とし、3ポート或いは4ポートで行った。経腹腔的に腎に到達し、腎周囲を電気メス、超音波凝固切開装置を用いて剥離した。尿管と腎茎部の血管はエンドループ或いはクリップを用いて切離し、臍の創より腎臓を摘出した。手術時間は中央値120分、麻酔時間217分、出血量0mlで、術中合併症はなかった。術後在院日数は中央値5.5日で、精嚢腺嚢胞切除を併施した1例に術後尿閉を認め、一時的な間歇導尿を要したが自然に軽快した。病理組織学的にはhypoplastickidnyが多く、一部にrenal dysplasiaを伴うものも認めた。

  240. 精巣を伴った鼠径部異所性陰嚢の一例

    高澤 慎也, 多田 実, 小林 堅一郎, 益子 貴行, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 神保 教広, 渡邊 彰二

    小児外科   Vol. 43 ( 9 ) page: 1003 - 1005   2011.9

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    1歳4ヵ月男児。出生時より右陰嚢が鼠径部に認められ、産院で異所性陰嚢と診断後、著者らの施設へ紹介来院となった。初診時、陰嚢右側は本来の位置から離れ右鼠径部にあり、内部には精巣が存在していた。一方、陰嚢左側と左精巣は正常の位置に存在しており、陰嚢正中に縫線が認められた。また他の体表奇形はみられず、腹部エコーでも泌尿生殖器系の異常は認められなかった。そこで、1歳4ヵ月目に手術が施行され、手術はZ形成術により右鼠径部の陰嚢を本来の位置に移動させた。その結果、合併症は認めず、術後5日目で退院となり、更に術後1ヵ月経過では右陰嚢の色調良好が確認された。尚、右精巣にも萎縮性変化は認められなかった。

  241. Sialolipoma of the submandibular gland in a child. Reviewed

    Sato K, Gotoh C, Uchida H, Kawashima H, Yoshida M, Kitano Y, Kishimoto H

    Journal of pediatric surgery   Vol. 46 ( 2 ) page: 408-10   2011.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2010.09.097

    PubMed

  242. 【小児腹部救急における腹腔鏡手術の適応と限界】 小児腹部救急疾患に対する腹腔鏡手術

    吉田 真理子, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 高澤 慎也, 岩中 督

    日本腹部救急医学会雑誌   Vol. 31 ( 1 ) page: 31 - 35   2011.1

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本腹部救急医学会  

    腹腔鏡手術は低侵襲で整容的に優れるため,腹部救急疾患に対しても適応が拡大しつつある。当科では最近12年間に,急性虫垂炎・肥厚性幽門狭窄症を除く小児腹部救急疾患75例に対し腹腔鏡手術を行った。診断は腸閉塞17例,脳室腹腔シャント障害9例,卵巣・卵管捻転8例,Meckel憩室(腸閉塞を除く),横隔膜ヘルニア各7例等であった。診断確定目的の腹腔鏡を21例に行い6例は観察のみで終了した。新生児例は捻転のない腸回転異常症と卵巣嚢腫捻転の計3例であった。術中小腸損傷は2例(2.5%),開腹移行は4例(5.0%)あった。腹部救急疾患に対して腹腔鏡手術を行うには,迅速な開腹移行にも対応できる,チームとしての熟練が必要である。腹腔鏡手術の絶対的禁忌は全身麻酔・気腹のハイリスク例であり,相対的禁忌として腸管壊死を伴う絞扼性イレウスがあげられるが,その他の症例では腹腔鏡手術の適応を考慮できると考えられた。(著者抄録)

    DOI: 10.11231/jaem.31.31

  243. WS2-03 Hirschsprung病根治術の術後合併症と排便機能 : 開腹Duhamel法と腹腔鏡補助下Soave伝田法の比較(Hirschsprung病術後の術式別排便機能,ワークショップII,第48回日本小児外科学会学術集会) Reviewed

    高澤 慎也, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 神保 教広, 宮川 亨平, 天野 日出, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 516 - 516   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_516_1

  244. 3.重症尿路感染後に無機能腎となり腹腔鏡下腎摘出術を施行した1例(一般演題,第45回日本小児外科学会関東甲信越地方会) Reviewed

    高澤 慎也, 多田 実, 小林 堅一郎, 内田 広夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 宮川 亨平, 天野 日出

    日本小児外科学会雑誌   Vol. 47 ( 3 ) page: 375 - 375   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.3_375_4

  245. 8.短腸症候群に尿路結石を合併した1例(一般演題,第40回日本小児外科代謝研究会) Reviewed

    高澤 慎也, 多田 実, 小林 堅一郎, 内田 広夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 宮川 亨平

    日本小児外科学会雑誌   Vol. 47 ( 2 ) page: 298 - 299   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.2_298_4

  246. 8.臍帯を利用し非縫合的腹壁閉鎖術を行った新生児腹壁異常の2例(一般演題,第45回日本小児外科学会関東甲信越地方会) Reviewed

    宮川 亨平, 内田 広夫, 五藤 周, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 天野 日出

    日本小児外科学会雑誌   Vol. 47 ( 3 ) page: 376 - 377   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.3_376_5

  247. O-16 腹腔鏡補助下鎖肛根治術の術後合併症と術後排便機能(鎖肛術後の排便機能,一般口演,第48回日本小児外科学会学術集会) Reviewed

    川嶋 寛, 内田 広夫, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 582 - 582   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_582_2

  248. O-27 単孔式腹腔鏡下鼠径ヘルニア根治術(SILPEC)におけるSILPEC鉗子の開発と有用性(私はこうしている(各種デバイスを用いた一工夫)2,一般口演,第48回日本小児外科学会学術集会) Reviewed

    神保 教広, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 588 - 588   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_588_1

  249. P-264 梨状窩瘻の診断と治療 : 梨状窩嚢胞と瘻孔の違いと確実な摘出法の確立(頸部,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    天野 日出, 内田 広夫, 佐藤 かおり, 川嶋 寛, 田中 裕次郎, 高澤 慎也, 神保 教広

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 715 - 715   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_715_2

  250. P-304 肺分画症を合併した横隔膜ヘルニアの3例(横隔膜2,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    高澤 慎也, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 神保 教広, 宮川 亨平, 天野 日出

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 732 - 732   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_732_1

  251. P-322 小児における器械吻合の有用性(手術の工夫,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 田中 裕次郎, 高澤 慎也, 神保 教広

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 741 - 741   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_741_1

  252. P-342 当院で経験した卵巣腫瘍58症例の検討と卵巣腫瘍茎捻転の治療戦略(良性腫瘍3,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    神保 教広, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 751 - 751   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_751_1

  253. P-350 腹腔内精巣より発生した成熟奇形腫の1例(良性腫瘍4,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    宮川 亨平, 多田 実, 小林 堅一郎, 内田 広夫, 川嶋 寛, 佐藤 かおり, 田中 裕次郎, 高澤 慎也, 神保 教広, 天野 日出, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 755 - 755   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_755_1

  254. P-46 小児における脾臓温存膵体尾部切除術の実際 : 2つの異なったアプローチによる脾臓温存の試み(膵・脾,ポスターセッション,第48回日本小児外科学会学術集会) Reviewed

    田中 裕次郎, 内田 広夫, 川嶋 寛, 佐藤 かおり, 高澤 慎也, 神保 教広, 宮川 亨平, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 610 - 610   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_610_2

  255. S1-04 極低出生体重児の腹部疾患の特殊性と手術の短期および長期予後(低出生体重児に対する外科治療の長期予後,シンポジウムI,第48回日本小児外科学会学術集会) Reviewed

    内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 490 - 490   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_490_2

  256. S5-5.極低出生体重児の外科疾患と予後(シンポジウム5「外科治療を受けた低出生体重児の予後」,低出生体重児の外科,第27回日本小児外科学会秋季シンポジウム) Reviewed

    田中 裕次郎, 内田 広夫, 佐藤 かおり, 高澤 慎也, 神保 教広

    日本小児外科学会雑誌   Vol. 47 ( 6 ) page: 929 - 929   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.6_929_2

  257. V-03 A型long gap食道閉鎖症に対する食道延長による二期的胸腔鏡下食道食道吻合術(ビデオセッション1,第48回日本小児外科学会学術集会) Reviewed

    田中 裕次郎, 内田 広夫, 川嶋 寛, 佐藤 かおり, 高澤 慎也, 神保 教広, 宮川 亨平, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 560 - 560   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_560_1

  258. V-13 腹腔鏡下根治術を施行した先天性十二指腸狭窄の1例(ビデオセッション3,第48回日本小児外科学会学術集会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 田中 裕次郎, 高澤 慎也, 神保 教広

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 565 - 565   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_565_1

  259. V-18 膵体部Solid pseudopapillary tumorに対する腹腔鏡下脾臓,脾動静脈温存膵体尾部切除術(ビデオセッション4,第48回日本小児外科学会学術集会) Reviewed

    内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 岸本 宏志

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 567 - 567   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_567_2

  260. V-19 膵中央切除を行ったSolid Pseudopapirally Tumorの1例(ビデオセッション4,第48回日本小児外科学会学術集会) Reviewed

    川嶋 寛, 内田 広夫, 神保 教広, 田中 裕次郎, 佐藤 かおり, 高澤 慎也

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 568 - 568   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_568_1

  261. V-20 下大静脈内腫瘍塞栓が肝静脈流入部を越えて浸潤した腎芽腫に対する下大静脈のplicationを用いた腫瘍摘出術(ビデオセッション5,第48回日本小児外科学会学術集会) Reviewed

    内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 神保 教広, 康 勝好, 松野 良介, 岸本 宏志, 野村 耕司

    日本小児外科学会雑誌   Vol. 47 ( 4 ) page: 568 - 568   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.4_568_2

  262. JOS-0912.腹腔鏡下に摘出した巨大後腹膜奇形腫の1乳児例(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    五藤 周, 内田 広夫, 川嶋 寛, 佐藤 かおり, 高澤 慎也, 田中 裕次郎, 宮川 亨平

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 182 - 183   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_182_3

  263. 12.完全胸腔鏡下に摘出した後縦隔まで進展した肺葉内肺分画症の1例(一般演題,第45回日本小児外科学会関東甲信越地方会) Reviewed

    天野 日出, 内田 広夫, 岸本 宏志, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 宮川 亨平

    日本小児外科学会雑誌   Vol. 47 ( 3 ) page: 377 - 377   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.3_377_4

  264. JOS-0862.腹腔鏡下精巣検索および手術に難渋した臍帯ヘルニア術後(Beckwith-Wiedemann症候群)の3症例(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    多田 実, 川嶋 寛, 内田 広夫, 小林 堅一郎, 宮川 享平, 高澤 慎也

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 167 - 167   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_167_1

  265. JOS-0867.経尿道的逆流防止術を施行した原発性膀胱尿管逆流症(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    小林 堅一郎, 多田 実, 高澤 慎也, 宮川 享平, 川嶋 寛, 内田 広夫

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 168 - 168   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_168_3

  266. JOS-0868.小児に対する腹腔鏡下腎摘除術(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    高澤 慎也, 多田 実, 小林 堅一郎, 内田 広夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 宮川 亨平

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 168 - 169   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_168_4

  267. JOS-0883.急性腹症における腹腔鏡手術の有用性(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 高澤 慎也, 宮川 亨平, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 173 - 174   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_173_3

  268. JOS-0890.3歳未満の乳幼児に対する完全胸腔鏡下肺切除術の検討 : 胸腔鏡補助下手術との比較(要望演題・一般演題,第30回日本小児内視鏡外科・手術手技研究会) Reviewed

    川嶋 寛, 内田 広夫, 五藤 周, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 宮川 亨平, 岩中 督

    日本小児外科学会雑誌   Vol. 47 ( 1 ) page: 175 - 176   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.1_175_3

  269. 33.肺靭帯を通して後縦隔まで進展した先天性肺葉内肺分画症の1例(セッション7 一般演題(嚢胞性肺疾患),第21回日本小児呼吸器外科研究会) Reviewed

    天野 日出, 内田 広夫, 岸本 宏志, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 宮川 亨平

    日本小児外科学会雑誌   Vol. 47 ( 7 ) page: 1094 - 1094   2011

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.47.7_1094_2

  270. Inguinal hernia repair in children using single-incision laparoscopic-assisted percutaneous extraperitoneal closure. Reviewed

    Uchida H, Kawashima H, Goto C, Sato K, Yoshida M, Takazawa S, Iwanaka T

    Journal of pediatric surgery   Vol. 45 ( 12 ) page: 2386-9   2010.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2010.08.037

    PubMed

  271. 当センターにおける完全胸腔鏡下および胸腔鏡補助下肺葉切除術の検討 Reviewed

    高澤 慎也, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 城 宏輔, 岩中 督

    埼玉県医学会雑誌   Vol. 45 ( 1 ) page: 91 - 93   2010.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:埼玉県医学会  

    2000年1月〜2009年12月に胸腔鏡補助下(VATS)12例および完全胸腔鏡下(CTL)肺葉切除3例について、手術成績・合併症などを後方視的に検討した。VATSとCTLにおける中央値はそれぞれ、手術時年齢5歳10ヵ月・1歳3ヵ月、手術時体重は17.8kg・9.5kg、手術時間は184分・222分、出血量は116g・28g、術後在院日数は8.5日・6日であった。VATSで1例が出血のため開胸移行したが、いずれも術後合併症は認めなかった。

  272. 【高位鎖肛 基礎から臨床の最前線まで】 腹腔鏡補助下肛門形成術後の問題点と排便機能

    内田 広夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 宮川 亨平, 石丸 哲也, 岩中 督

    小児外科   Vol. 42 ( 11 ) page: 1187 - 1190   2010.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    2005年以降に腹腔鏡補助下肛門形成術(LAARP)を施行した28症例(男児22例、女児6例、手術時平均月齢6.5±3.1ヵ月)を対象に術式の問題点および術後の排便機能について後方視的に検討した。その結果、平均手術時間は194±61分、出血量は7.8±8.4mlで、早期合併症としては直腸肛門縫合不全が3例にみられ、1例は保存的に軽快、2例は再吻合を要した。晩期合併症としては大きな尿道後部嚢胞が3例にみられ、うち2例は嚢胞摘出標本に直腸粘膜がみられたことから、瘻孔切離部が直腸側に寄りすぎたため遺残瘻孔となり、徐々に増大したと考えられた。術後1年以上経過時に施行のMRIでは1.5cm以下の嚢胞が6例に認められたが、それらは2年以上経過しても増大傾向はみられなかった。排便機能は4歳時では1日おきに浣腸を行っている症例が多くみられたが、失禁はほとんどみられず時に汚染がみられる症例が多かった。7・8歳時では4歳時と比べ各項目で徐々に改善がみられ、便意と総合点では有意な改善が認められた。尚、肛門静止圧・肛門管長・直腸肛門弛緩反射についてはPSARPと差は認められなかった。

  273. Laparoscopic spleen-preserving distal pancreatectomy for solid pseudopapillary tumor with conservation of splenic vessels in a child. Reviewed

    Uchida H, Goto C, Kishimoto H, Kawashima H, Sato K, Yoshida M, Takazawa S

    Journal of pediatric surgery   Vol. 45 ( 7 ) page: 1525-9   2010.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2010.03.013

    PubMed

  274. Histopathologic improvement in biliary cirrhosis after definitive surgery for choledochal cyst Reviewed International journal

    Tetsuya Ishimaru, Yoshihiro Kitano, Hiroo Uchida, Hiroshi Kawashima, Chikashi Gotoh, Kaori Satoh, Mariko Yoshida, Hiroshi Kishimoto, Tadashi Iwanaka

    JOURNAL OF PEDIATRIC SURGERY   Vol. 45 ( 5 ) page: E11 - E14   2010.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:W B SAUNDERS CO-ELSEVIER INC  

    Choledochal cyst causes liver fibrosis, the extent of which varies with each case. Liver damage seldom progresses to cirrhosis, but when it does, it is generally irreversible. We report an infantile case of liver cirrhosis associated with choledochal cyst in which complete clinical resolution was achieved by surgery. Pancytopenia caused by splenomegaly, massive ascites, hypoalbuminemia, and coagulation abnormality that were observed during the early postoperative period had disappeared within 4 months after surgery. Needle liver biopsy performed at 1 year after surgery revealed marked improvement in liver fibrosis. (C) 2010 Elsevier Inc. All rights reserved.

    DOI: 10.1016/j.jpedsurg.2010.01.030

    Web of Science

    PubMed

  275. 重症心身障害児における小児外科医の役割 腹腔鏡下噴門形成術の長期予後 Reviewed

    川嶋 寛, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 524 - 524   2010.5

  276. S7-4.重症心身障害児に発症した絞扼性イレウスの4例(シンポジウム7「緊急手術」,障がい児を支える-小児外科医の役割-,第26回日本小児外科学会秋季シンポジウム) Reviewed

    五藤 周, 内田 広夫, 川嶋 寛, 田中 裕次郎, 佐藤 かおり, 高澤 慎也, 宮川 亨平

    日本小児外科学会雑誌   Vol. 46 ( 6 ) page: 911 - 912   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.6_911_2

  277. PS-140 術創が残らない単孔式腹腔鏡下鼠径ヘルニア根治術(SILPEC)の確立(内視鏡手術の進歩2,ポスターシンポジウム,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会) Reviewed

    内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 560 - 560   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.3_560_2

  278. PS-119 小児急性虫垂炎に対する保存療法の有用性 : 待機手術は本当に必要か?(虫垂炎の診断と治療,ポスターシンポジウム,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会) Reviewed

    吉田 真理子, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 550 - 550   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.3_550_1

  279. 11.術前に頭蓋内出血を認めた胆道閉鎖症の7例(一般演題,第36回日本胆道閉鎖症研究会) Reviewed

    五藤 周, 内田 広夫, 川嶋 寛, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 4 ) page: 820 - 821   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.4_820_4

  280. 11. 腹腔鏡補助下造肛術の術後合併症(要望演題II,第66回直腸肛門奇形研究会) Reviewed

    内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也, 岩中 督, 石丸 哲也

    日本小児外科学会雑誌   Vol. 46 ( 1 ) page: 136 - 136   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.1_136_1

  281. PO-205 当院における小腸瘻閉鎖術の術後合併症と小児における器械吻合の可能性(各種手術の工夫,ポスターセッション,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 701 - 701   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.3_701_1

  282. PS-059 当センターにおける先天性肺嚢胞性疾患に対する術式の検討(頚・胸部疾患治療の最前線,ポスターシンポジウム,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会) Reviewed

    高澤 慎也, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 520 - 520   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.3_520_1

  283. PS-068 腹腔鏡下噴門形成術の長期予後(重症心身障害児における小児外科医の役割2,ポスターシンポジウム,病気の子供達に笑顔 小児外科に夢そして革新を,第47回 日本小児外科学会学術集会) Reviewed

    川嶋 寛, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 3 ) page: 524 - 524   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.3_524_2

  284. 16.原因不明の発熱・下痢・嘔吐を繰り返した1乳児例(一般演題,第44回日本小児外科学会関東甲信越地方会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 4 ) page: 800 - 800   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.4_800_3

  285. 84.新生児・乳児における腸捻転症53例の検討(一般演題,第29回日本小児内視鏡外科・手術手技研究会) Reviewed

    吉田 真理子, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 6 ) page: 1011 - 1011   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.6_1011_3

  286. 55.両側腎動脈瘤の1男児例(一般演題,第29回日本小児内視鏡外科・手術手技研究会) Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子, 高澤 慎也

    日本小児外科学会雑誌   Vol. 46 ( 6 ) page: 1004 - 1004   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.6_1004_2

  287. 20.肛門膣前庭瘻に子宮・膣欠損を合併した1例(一般演題,第29回日本小児内視鏡外科・手術手技研究会) Reviewed

    高澤 慎也, 五藤 周, 内田 広夫, 川嶋 寛, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 46 ( 6 ) page: 995 - 996   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.6_995_4

  288. 2.小児膵疾患に対する内視鏡的経乳頭的治療の経験(一般演題,第37回日本小児内視鏡研究会) Reviewed

    高澤 慎也, 糸井 隆夫, 川嶋 寛, 五藤 周, 田中 裕次郎, 佐藤 かおり, 宮川 享平, 内田 広夫

    日本小児外科学会雑誌   Vol. 46 ( 6 ) page: 1014 - 1015   2010

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.46.6_1014_4

  289. 小児内視鏡外科における機能温存と低侵襲の追及 小児内視鏡手術における機能温存と低侵襲の追求 胸腔鏡下食道閉鎖症根治術 Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也, 古村 眞, 田中 裕次郎, 石丸 哲也

    日本内視鏡外科学会雑誌   Vol. 14 ( 7 ) page: 203 - 203   2009.12

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本内視鏡外科学会  

  290. 重症心身障害児に対する内視鏡手術 胃食道逆流症とその治療戦略 Reviewed

    川嶋 寛, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本内視鏡外科学会雑誌   Vol. 14 ( 7 ) page: 276 - 276   2009.12

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本内視鏡外科学会  

  291. 腹腔鏡補助下鎖肛根治術の問題点と術後排便機能 Reviewed

    内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也

    日本内視鏡外科学会雑誌   Vol. 14 ( 7 ) page: 391 - 391   2009.12

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(一社)日本内視鏡外科学会  

  292. Stage 3の神経芽腫に対して集学的な治療は必要か Reviewed

    内田 広夫, 康 勝好, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也, 花田 良二

    小児がん   Vol. 46 ( プログラム・総会号 ) page: 312 - 312   2009.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(NPO)日本小児がん学会  

  293. 【低出生体重児の外科Update】院外出生後、当センターに搬送された低出生体重児の外科手術症例 Reviewed

    川嶋 寛, 内田 広夫, 吉田 真理子

    小児外科   Vol. 41 ( 11 ) page: 1222 - 1225   2009.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:(株)東京医学社  

    1999〜2008年の10年間に著者等の施設における2500g未満の低出生体重児で外科手術を行った124症例(男児71例、女児53例)を対象に、出生体重・在胎週数・診断・予後について後方視的に検討した。その結果、平均在胎週数は34(21〜41)週、出生体重は平均1817(506〜2486)gで、出生体重の内訳は1000g未満の超低出生体重児25例、1000g以上1500g未満の極低出生体重児10例、1500g以上2500g未満の低出生体重児89例であった。疾病別では腸閉鎖・狭窄22例、消化管穿孔21例、直腸肛門奇形20例、食道閉鎖症16例、腸回転異常症8例、壊死性腸炎7例、臍帯ヘルニア6例、腹壁破裂5例、肥厚性幽門狭窄症4例、横隔膜ヘルニア・ヒルシュスプルング病・胆道閉鎖症各2例であった。出生前診断は124例中14例(11.2%)で、全国集計の26.7%より胎児診断率が低かった。予後では術後死亡率は13%(16例)で全国集計の16.2%と同等であった。

  294. Growth spurt-related recurrence after Nuss procedure Reviewed International journal

    Tetsuya Ishimaru, Yoshihiro Kitano, Hiroo Uchida, Hiroshi Kawashima, Chikashi Gotoh, Kaori Satoh, Mariko Yoshida, Ayanori Sugita, Tadashi Iwanaka

    JOURNAL OF PEDIATRIC SURGERY   Vol. 44 ( 8 ) page: E13 - E16   2009.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:W B SAUNDERS CO-ELSEVIER INC  

    We report 2 cases of growth spurt-related recurrence after Nuss procedure. Each of the 2 cases underwent bar insertion at the age of 6 and I I years, respectively. The support bar was removed 2 years later followed by severe redepression during the growth spurt. One patient underwent redo Nuss procedure elsewhere. The other patient was diagnosed as idiopathic precocious puberty and is in treatment. The possibility of growth spurt-related recurrence must be explained to those who undergo early correction before surgery, and follow-up is mandatory at least until patients&apos; puberty is over. (C) 2009 Elsevier Inc. All rights reserved.

    DOI: 10.1016/j.jpedsurg.2009.04.014

    Web of Science

    PubMed

  295. 当院における先天性胆道拡張症の長期予後 Reviewed

    佐藤 かおり, 内田 広夫, 川嶋 寛, 五藤 周, 芳田 真理子, 高澤 慎也

    日本膵・胆管合流異常研究会プロシーディングス   Vol. 32   page: 41 - 41   2009.8

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:日本膵・胆管合流異常研究会  

  296. Recurrence of a congenital pancreatic cyst mimicking omental cyst after laparoscopic cyst resection. Reviewed

    Ishimaru T, Uchida H, Yotsumoto K, Gotoh C, Yoshida M, Oguma E, Kishimoto H, Iwanaka T, Kitano Y

    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie   Vol. 19 ( 1 ) page: 53-4   2009.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/s-2008-1038590

    PubMed

  297. Residual fistula after laparoscopically assisted anorectoplasty: is it a rare problem? Reviewed

    Uchida H, Iwanaka T, Kitano Y, Kudou S, Ishimaru T, Yotsumoto K, Gotoh C, Yoshida M

    Journal of pediatric surgery   Vol. 44 ( 1 ) page: 278-81   2009.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2008.10.056

    PubMed

  298. S4-4.腹腔鏡補助下造肛術の術後合併症と排便機能(シンポジウム4「鏡視下鎖肛手術の適応と問題点」,術後評価からみた高位鎖肛各術式の功罪,第25回日本小児外科学会秋季シンポジウム) Reviewed

    内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 高澤 慎也, 岩中 督

    日本小児外科学会雑誌   Vol. 45 ( 6 ) page: 920 - 921   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.6_920_2

  299. P-123 当科での臍ヘルニア・臍突出に対する手術方法(ポスター へそ4,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    佐藤 かおり, 北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 584 - 584   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_584_2

  300. 15.腹腔鏡補助下鎖肛根治術の功罪(一般演題,第19回日本小児外科QOL研究会) Reviewed

    内田 広夫, 北野 良博, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 5 ) page: 890 - 890   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.5_890_2

  301. MW-01 非触知精巣に対する腹腔鏡手術(ミニワークショップ 停留精巣・非蝕知精巣をどうするか?,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    川嶋 寛, 多田 実, 小林 堅一郎, 北野 良博, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 447 - 447   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_447_1

  302. O-33 開腹手術歴のない腸閉塞に対する腹腔鏡下手術の有用性(一般口演 虫垂炎・ヘルニア他,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    内田 広夫, 北野 良博, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 499 - 499   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_499_1

  303. O-37 ラブドイド腫瘍8例の検討(一般口演 悪性腫瘍,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    吉田 真理子, 北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 501 - 501   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_501_2

  304. O-78 小児外科学会指導医の現状(一般口演 その他,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 522 - 522   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_522_2

  305. P-008 当院で手術した胆道閉鎖症90例の予後(ポスター 移植2,Science and Art for Sick Children,第46回日本小児外科学会学術集会) Reviewed

    北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 3 ) page: 526 - 526   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.3_526_2

  306. 22.再発予防の観点から再考したNuss法の至適手術時期(要望演題・一般演題,第28回日本小児内視鏡外科・手術手技研究会) Reviewed

    石丸 哲也, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子, 杉田 礼典, 北野 良博

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 297 - 298   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_297_4

  307. 8.肛門膣前庭瘻に対するanterior sagittal anorectoplasty(ASARP)(要望演題「低位鎖肛治療のコンセンサス」,第65回直腸肛門奇形研究会) Reviewed

    五藤 周, 北野 良博, 内田 広夫, 川嶋 寛, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 269 - 270   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_269_5

  308. 8.当院における喉頭気管分離術症例のまとめ(一般演題,第19回日本小児呼吸器外科研究会) Reviewed

    吉田 真理子, 北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 274 - 274   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_274_1

  309. 5.無瘻孔性鎖肛の初期診断(要望演題「低位鎖肛治療のコンセンサス」,第65回直腸肛門奇形研究会) Reviewed

    北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 269 - 269   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_269_2

  310. 42.再手術を要した手術合併症(要望演題・一般演題,第28回日本小児内視鏡外科・手術手技研究会) Reviewed

    北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 302 - 303   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_302_4

  311. 35. 卵管捻転の3例(第43回日本小児外科学会関東甲信越地方会) Reviewed

    佐藤 かおり, 北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 4 ) page: 794 - 794   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.4_794_3

  312. 33.重症心身障害児の胃食道逆流症に対する治療戦略(要望演題・一般演題,第28回日本小児内視鏡外科・手術手技研究会) Reviewed

    内田 広夫, 北野 良博, 佐藤 かおり, 川嶋 寛, 五藤 周, 吉田 真理子

    日本小児外科学会雑誌   Vol. 45 ( 2 ) page: 300 - 300   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.2_300_3

  313. 32. 高位鎖肛に対する腹腔鏡補助下根治術後の機能評価(一般演題,第38回日本小児消化管機能研究会) Reviewed

    工藤 寿美, 北野 良博, 内田 広夫, 四本 克己, 石丸 哲也, 五藤 周, 川嶋 寛, 金子 道夫, 岩中 督

    日本小児外科学会雑誌   Vol. 45 ( 4 ) page: 813 - 814   2009

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.45.4_813_5

  314. Seminal vesicle abscesses associated with ipsilateral multicystic dysplastic kidney in an infant. Reviewed

    Fujinaga S, Hirano D, Hara S, Uchida H, Kitano Y, Kobayashi K, Tada M, Someya T, Ohtomo Y, Shimizu T

    Pediatric nephrology (Berlin, Germany)   Vol. 23 ( 9 ) page: 1551-4   2008.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00467-008-0839-5

    PubMed

  315. Present status of pancreas transplantation in Japan-donation predominantly from marginal donors and modified surgical technique: Report of Japan pancreas transplantation registry Reviewed

    Ishibashi M., Ito T., Sugitani A., Furukawa H., Sekiguchi S., Gotoh M., Teraoka S., Sato Y., Matsuno N., Kenmochi S., Uchida H., Yoshimura N., Nakajima Y., Kuroda Y., Odan H., Idezuki Y., Kanazawa Y.

    TRANSPLANTATION PROCEEDINGS   Vol. 40 ( 2 ) page: 486 - 490   2008.3

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.transproceed.2008.01.047

    Web of Science

  316. Present status of pancreas transplantation in Japan-donation predominantly from marginal donors and modified surgical technique: Report of Japan pancreas transplantation registry Reviewed

    M. Ishibashi, T. Ito, A. Sugitani, H. Furukawa, S. Sekiguchi, M. Gotoh, S. Teraoka, Y. Sato, N. Matsuno, S. Kenmochi, H. Uchida, N. Yoshimura, Y. Nakajima, Y. Kuroda, H. Odan, Y. Idezuki, Y. Kanazawa

    TRANSPLANTATION PROCEEDINGS   Vol. 40 ( 2 ) page: 486 - 490   2008.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE INC  

    In Japan, organ donation has been still limited because of the strict donor criteria. The aim of this study was to show the effectiveness of pancreas transplantation (PTx) by analyzing the outcomes even under poor donor conditions. Thirty-six cases of PTx (32 simultaneous pancreas and kidney transplantations [SPK], 4 pancreas after kidney transplantations) performed during the last 8 years were examined especially for donor characteristics. Mean donor age of 41.4 +/- 11.9 years was considerably older compared with that in the United States and Europe; donors aged over 40 years comprised 67% of the total. According to the criteria described by Kapur, 29 cases (81%) in our series would be considered marginal. Thus, to increase blood supply into the pancreatic head, the gastroduodenal artery (GDA) was anastomosed using donor artery to common hepatic artery or iliac Y graft. These procedures were performed in 16 of the 24 cases in which there was liver procurement. Eventually, 34 cases (94%) preserved GDA continuity. Mean total cold ischemic time of pancreatic grafts was 12 hours 1.5 minutes. Of 214 registrants, 17 patients on the waiting list for SPK died of diabetic complications. To date, patient survival remains 100% with a mean follow-up period of 33 months. Pancreas graft survivals at 1, 3, and 5 years posttransplantation were 92%, 80%, and 80%, respectively. In contrast, kidney survivals were 91%, 91%, and 91%, respectively. The integrity of the pancreas head and duodenum by preservation of the GDA continuity might have decreased the risk associated with the marginal donors.

    DOI: 10.1016/j.transproceed.2008.01-047

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  317. S2-5.高位鎖肛に対する腹腔鏡補助下造肛術 : 術後排便機能と晩期合併症(シンポジウム-2:直腸肛門奇形,小児内視鏡手術,第24回日本小児外科学会秋季シンポジウム) Reviewed

    岩中 督, 川嶋 寛, 内田 広夫, 北野 良博, 工藤 寿美, 江村 隆起

    日本小児外科学会雑誌   Vol. 44 ( 6 ) page: 764 - 765   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.44.6_764_2

  318. S4-1.腹腔鏡下幽門筋切開術(シンポジウム-4:幽門狭窄症,小児内視鏡手術,第24回日本小児外科学会秋季シンポジウム) Reviewed

    佐藤 かおり, 北野 良博, 内田 広夫, 川嶋 寛, 五藤 周, 吉田 真理子

    日本小児外科学会雑誌   Vol. 44 ( 6 ) page: 781 - 782   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.44.6_781_2

  319. S5-1.腹腔鏡下噴門形成術 : 当院での手術法(シンポジウム-5:噴門形成術,小児内視鏡手術,第24回日本小児外科学会秋季シンポジウム) Reviewed

    川嶋 寛, 北野 良博, 内田 広夫, 五藤 周, 佐藤 かおり, 吉田 真理子

    日本小児外科学会雑誌   Vol. 44 ( 6 ) page: 784 - 784   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.44.6_784_2

  320. VS-005 Laparoscopic fundoplication-Our procedure(Video Symposium Endoscopic surgical skill qualification system in pediatric minimally invasive surgery using laparoscopic fundoplication,Better Life for Sick Children, Better Future for Pediatric Surgery,the 45th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Kawashima Hiroshi

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 44 ( 3 ) page: 386 - 386   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.44.3_386

  321. B-049 Patient satisfaction of Nuss Procedure(Oral Presentation Funnel chest,Better Life for Sick Children, Better Future for Pediatric Surgery,the 45th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Ishimaru Tetsuya

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 44 ( 3 ) page: 410 - 410   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.44.3_410_2

  322. B-011 Our screening program for solid tumors in patients with malformation syndromes(Oral Presentation Oncology 2,Better Life for Sick Children, Better Future for Pediatric Surgery,the 45th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Yoshida Mariko

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 44 ( 3 ) page: 392 - 392   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.44.3_392_1

  323. 42 腹腔鏡下噴門形成術再手術後に生じた絞扼性横隔膜ヘルニアの1例(一般演題,第27回日本小児内視鏡外科・手術手技研究会) Reviewed

    五藤 周, 北野 良博, 内田 広夫, 四本 克己, 石丸 哲也, 芳田 真理子, 岩中 督, 川嶋 寛

    日本小児外科学会雑誌   Vol. 44 ( 1 ) page: 102 - 102   2008

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.44.1_102_3

  324. The laparoscopic approach of neuroblastoma. Reviewed

    Iwanaka T, Kawashima H, Uchida H

    Seminars in pediatric surgery   Vol. 16 ( 4 ) page: 259-65   2007.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.sempedsurg.2007.06.008

    PubMed

  325. Usability Needs to be Improved for Patient Safety Reviewed

    SOMA T, UCHIDA H, HITSUISHI H, TAKEDA S, NAKAJIMA K

    Japan Journal of Medical Informatics   Vol. 27 ( 1 ) page: 29 - 32   2007.5

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Association for Medical Informatics  

    Information and communication technology has been introduced rapidly into health-care field, and can contribute to system complexity and new human errors. Nielsen has defined 5 facets of usability: learnability, efficiency, memorability, errors and satisfaction. The more the usability progress, the more likely patient safety will be achieved, however, there is the trade-off relationship between safety ensuring and efficiency seeking. Technology needs to be designed and improved to support real workflow and care processes.

    DOI: 10.14948/jami.27.29

  326. R-006 Evaluation of laparoscopically assisted anorectoplasty for high and intermediate-type imperforted anus(Minimally invasive surgery I, the 44th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Uchida Hiroo

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 43 ( 3 ) page: 373 - 373   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.43.3_373_2

  327. P-274A A rare case of chronic pancreatitis with choledochal cyst and pancreaticobiliary malformation(Newborn surgery 2/Hepatobiliary, the 44th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Yotsumoto Katsumi

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 43 ( 3 ) page: 573 - 573   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.43.3_573_2

  328. 14.小児肺疾患に対する胸腔鏡および胸腔鏡補助下手術症例の検討(第17回日本小児呼吸器外科研究会) Reviewed

    内田 広夫, 岩中 督, 四本 克己, 川嶋 寛, 石丸 哲也, 五藤 周

    日本小児外科学会雑誌   Vol. 43 ( 4 ) page: 648 - 648   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.4_648_2

  329. 12.Caudal duplicationの2例(II.第63回直腸肛門奇形研究会抄録(主題:重複肛門),第63回直腸肛門奇形研究会) Reviewed

    石丸 哲也, 岩中 督, 内田 広夫, 四本 克己, 川嶋 寛, 五藤 周, 多田 実, 小林 堅一郎, 岩中 督

    日本小児外科学会雑誌   Vol. 43 ( 1 ) page: 125 - 125   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.1_125_1

  330. 1.新生児期に手術を施行した先天性梨状窩嚢胞の2例(一般演題,第26回日本小児内視鏡外科・手術手技研究会) Reviewed

    石丸 哲也, 岩中 督, 内田 広夫, 四本 克己, 川嶋 寛, 五藤 周, 岩中 督

    日本小児外科学会雑誌   Vol. 43 ( 1 ) page: 104 - 104   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.1_104_2

  331. P-032B Surgical complications with open Duhamel procedure and laparoscopy assisted endorectal pullthrough(Gastrointestinal, the 44th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Ishimaru Tetsuya

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 43 ( 3 ) page: 452 - 452   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.43.3_452_2

  332. P-273A Surgical disorders in neonates with trisomy 13 and trisomy 18(Newborn surgery 2/Hepatobiliary, the 44th Annual Meeting of Japanese Society of Pediatric Surgeons) Reviewed

    Gotoh Chikashi

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 43 ( 3 ) page: 573 - 573   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    DOI: 10.11164/jjsps.43.3_573_1

  333. 18.小児内鏡視手術の術中,術後合併症の検討(一般演題,第26回日本小児内視鏡外科・手術手技研究会) Reviewed

    五藤 周, 岩中 督, 内田 広夫, 四本 克己, 川嶋 寛, 石丸 哲也

    日本小児外科学会雑誌   Vol. 43 ( 1 ) page: 109 - 109   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.1_109_1

  334. 65.ターナー症候群の索状性腺に対する腹腔鏡下性腺摘除術の手術経験(一般演題,第26回日本小児内視鏡外科・手術手技研究会) Reviewed

    四本 克己, 岩中 督, 内田 広夫, 川嶋 寛, 五藤 周, 石丸 哲也, 岩中 督, 会津 克哉, 望月 弘

    日本小児外科学会雑誌   Vol. 43 ( 1 ) page: 121 - 121   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.1_121_1

  335. 3.顎下腺に生じたsialolipomaの1例(一般演題,第41回日本小児外科学会関東甲信越地方会) Reviewed

    五藤 周, 岩中 督, 内田 広夫, 四本 克己, 川嶋 寛, 石丸 哲也, 岸本 宏志

    日本小児外科学会雑誌   Vol. 43 ( 6 ) page: 794 - 794   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.6_794_3

  336. 23.下部空腸に胎便が充満したmeconium diseaseの1例(一般演題,第41回日本小児外科学会関東甲信越地方会) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 四本 克己, 五藤 周, 石丸 哲也, 藤澤 ますみ, 鬼本 博文

    日本小児外科学会雑誌   Vol. 43 ( 6 ) page: 799 - 799   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.6_799_1

  337. 20.過去10年間のHirschsprung病の検討 : Duhamel池田法と腹腔鏡補助下Soave伝田法の比較(一般演題,第37回日本小児消化管機能研究会) Reviewed

    石丸 哲也, 北野 良博, 内田 広夫, 四本 克己, 五藤 周, 芳田 真理子, 岩中 督

    日本小児外科学会雑誌   Vol. 43 ( 5 ) page: 709 - 709   2007

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.43.5_709_4

  338. P-62 待機的腹腔鏡下虫垂切除術;その効用と妥当性の検討(示説15 小腸2,第43回 日本小児外科学会総会) Reviewed

    内田 広夫, 岩中 督, 岸本 宏志, 川嶋 寛, 四本 克己, 石丸 哲也, 五藤 周, 浜野 志穂

    日本小児外科学会雑誌   Vol. 42 ( 3 ) page: 450 - 450   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.3_450_2

  339. 16. 新生児十二指腸穿孔の1例(第40回日本小児外科学会関東甲信越地方会) Reviewed

    石丸 哲也, 岩中 督, 内田 広夫, 川嶋 寛, 四本 克己, 五藤 周, 浜野 志穂

    日本小児外科学会雑誌   Vol. 42 ( 1 ) page: 111 - 111   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.1_111_4

  340. Or-55 腹腔鏡下幽門筋切開術の臨床的検討(口演14 内視鏡,第43回 日本小児外科学会総会) Reviewed

    浜野 志穂, 岩中 督, 川嶋 寛, 内田 広夫, 四本 克己, 石丸 哲也, 五藤 周

    日本小児外科学会雑誌   Vol. 42 ( 3 ) page: 414 - 414   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.3_414_1

  341. Or-56 腹腔鏡下噴門形成術後に再発した6症例 : 再発原因の検討と腹腔鏡下再手術(口演14 内視鏡,第43回 日本小児外科学会総会) Reviewed

    石丸 哲也, 岩中 督, 内田 広夫, 川嶋 寛, 四本 克己, 五藤 周, 浜野 志穂

    日本小児外科学会雑誌   Vol. 42 ( 3 ) page: 414 - 414   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.3_414_2

  342. 18. 小児慢性排便障害に対する結腸瘻ボタンを用いた腹腔鏡下順行性浣腸路の経験(第25回日本小児内視鏡外科・手術手技研究会) Reviewed

    浜野 志穂, 岩中 督, 四本 克己, 内田 広夫, 川嶋 寛, 五藤 周, 石丸 哲也

    日本小児外科学会雑誌   Vol. 42 ( 1 ) page: 149 - 149   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.1_149_3

  343. 7.腹腔鏡下肥厚性幽門狭窄症の手術と消化管機能(一般演題,第36回日本小児消化管機能研究会) Reviewed

    浜野 志穂, 岩中 督, 川嶋 寛, 内田 広夫, 四本 克己, 石丸 哲也

    日本小児外科学会雑誌   Vol. 42 ( 4 ) page: 546 - 546   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.4_546_4

  344. 49. 超低出生体重児腸重積症の1例(第25回日本小児内視鏡外科・手術手技研究会) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 四本 克己, 五藤 周, 浜野 志穂, 石丸 哲也, 長澤 真由美, 鬼本 博文

    日本小児外科学会雑誌   Vol. 42 ( 1 ) page: 157 - 157   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.1_157_2

  345. 25. 食道狭窄, 胃食道逆流症, 先天性食道裂孔ヘルニアを合併し診断・治療に難渋したBPFMの1例(第25回日本小児内視鏡外科・手術手技研究会) Reviewed

    四本 克己, 岩中 督, 内田 広夫, 川嶋 寛, 石丸 哲也, 五藤 周, 浜野 志穂, 岸本 宏志

    日本小児外科学会雑誌   Vol. 42 ( 1 ) page: 151 - 151   2006

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.42.1_151_2

  346. Midterm follow-up study of high-type imperforate anus after laparoscopically assisted anorectoplasty. Reviewed

    Kudou S, Iwanaka T, Kawashima H, Uchida H, Nishi A, Yotsumoto K, Kaneko M

    Journal of pediatric surgery   Vol. 40 ( 12 ) page: 1923-6   2005.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jpedsurg.2005.08.008

    PubMed

  347. B-51 食道閉鎖症long gap症例の術後長期予後について(食道) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 3 ) page: 455 - 455   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.3_455_1

  348. A-21 小児内視鏡下手術における術中合併症予防の工夫(鏡視下手術の合併症予防の工夫) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 四本 克己, 西 明, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 3 ) page: 375 - 375   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.3_375_1

  349. B-32 腹腔鏡下噴門形成術の手術適応と合併症 : 当センター78例の検討(内視鏡・内視鏡手術) Reviewed

    内田 広夫, 岩中 督, 川嶋 寛, 西 明, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 3 ) page: 450 - 450   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.3_450_2

  350. 22. 胆道閉鎖症疑診例に対する腹腔鏡下肝門部観察および胆道造影の適応と有用性(第31回胆道閉鎖症研究会) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 4 ) page: 706 - 706   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.4_706_2

  351. 40. 食道閉鎖症術後のGER手術適応について(コンセンサスカンファレンス(GERDの手術適応): 食道閉鎖症術後, 第35回日本小児消化管機能研究会) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 6 ) page: 839 - 839   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.6_839_1

  352. 38.交通外傷により肛門から結腸の脱出がみられた小児の1例(第39回日本小児外科学会関東甲信越地方会) Reviewed

    内田 広夫, 岩中 督, 西 明, 川嶋 寛, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 1 ) page: 90 - 91   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.1_90_4

  353. 33. 重症心身障害児の胃食道逆流症に対する手術適応(コンセンサスカンファレンス(GERDの手術適応): 重症心身障害児(者), 第35回日本小児消化管機能研究会) Reviewed

    内田 広夫, 岩中 督, 川嶋 寛, 西 明, 四本 克己, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 6 ) page: 837 - 837   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.6_837_2

  354. 32.吐血, 腹腔内遊離ガス像を認めた急性虫垂炎の1例(第39回日本小児外科学会関東甲信越地方会) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 四本 克己, 西 明, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 1 ) page: 89 - 89   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.1_89_3

  355. 27. 呼吸障害を合併する胃食道逆流症に対する腹腔鏡下噴門形成術の手術適応(コンセンサスカンファレンス(GERDの手術適応): 呼吸器症状, 第35回日本小児消化管機能研究会) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 四本 克己, 西 明, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 41 ( 6 ) page: 836 - 836   2005

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.41.6_836_1

  356. Complications of laparoscopic surgery in neonates and small infants. Reviewed

    Iwanaka T, Uchida H, Kawashima H, Nishi A, Kudou S, Satake R

    Journal of pediatric surgery   Vol. 39 ( 12 ) page: 1838-41   2004.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  357. Infantile intestinal leiomyosarcoma is prognostically favorable despite histologic aggressiveness: case report and literature review. Reviewed

    Yamamoto H, Tsuchiya T, Ishimaru Y, Kisaki Y, Fujino J, Uchida H, Yoshida M, Mori Y, Ikeda H

    Journal of pediatric surgery   Vol. 39 ( 8 ) page: 1257-60   2004.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  358. D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics. Reviewed

    Uchida H, Yamamoto H, Kisaki Y, Fujino J, Ishimaru Y, Ikeda H

    Journal of pediatric surgery   Vol. 39 ( 4 ) page: 634-6   2004.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  359. Umbilicoplasty for large protruding umbilicus accompanying umbilical hernia: a simple and effective technique. Reviewed

    Ikeda H, Yamamoto H, Fujino J, Kisaki Y, Uchida H, Ishimaru Y, Hasumi T, Hamajima A

    Pediatric surgery international   Vol. 20 ( 2 ) page: 105-7   2004.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00383-003-1097-z

    PubMed

  360. Epidermoid cyst: rare testicular tumor in children. Reviewed

    Fujino J, Yamamoto H, Kisaki Y, Ishimaru Y, Uchida H, Mori Y, Nozaki M, Ikeda H

    Pediatric radiology   Vol. 34 ( 2 ) page: 172-4   2004.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00247-003-1052-0

    PubMed

  361. P-177 当センターにおける鎖肛根治術の変遷と周術期の問題点(示説 直腸肛門奇形) Reviewed

    工藤 寿美, 岩中 督, 内田 広夫, 西 明, 川嶋 寛, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 40 ( 3 ) page: 526 - 526   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.3_526_1

  362. 14. 術後直腸狭窄に対する経肛門的狭窄切開術の経験(第30回日本小児内視鏡研究会) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 工藤 寿美, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 40 ( 2 ) page: 223 - 224   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.2_223_4

  363. 11. ITPに対する腹腔鏡下脾摘術中の血小板数の変動について(第17回日本小児脾臓研究会) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 工藤 寿美, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 40 ( 2 ) page: 231 - 231   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.2_231_2

  364. 1. 腹腔鏡下噴門形成術の再発症例に対する腹腔鏡下手術(セッション8 ミニシンポジウム1 : 内視鏡手術における合併症の予防と対処法)(第23回日本小児外科手術手技・小児内視鏡手術研究会) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 西 明, 工藤 寿美, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 40 ( 1 ) page: 160 - 160   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.1_160_2

  365. P-143 突然の小腸穿孔で発症したクロストリディウム腸炎の1例(示説 十二指腸・小腸1) Reviewed

    川嶋 寛, 岩中 督, 内田 広夫, 西 明, 工藤 寿美, 佐竹 亮介, 岸本 宏志

    日本小児外科学会雑誌   Vol. 40 ( 3 ) page: 509 - 509   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.3_509_1

  366. 2. 腹腔鏡下造肛術時の膣,尿道の同定の工夫(セッション9 腹腔鏡,手術手技 : 直腸肛門・泌尿生殖器1)(第23回日本小児外科手術手技・小児内視鏡手術研究会) Reviewed

    西 明, 岩中 督, 内田 広夫, 川嶋 寛, 工藤 寿美, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 40 ( 1 ) page: 162 - 162   2004

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.40.1_162_2

  367. Impact of graft length on surgical damage after intestinal transplantation in rats. Reviewed

    Inoue S, Tahara K, Sakuma Y, Hori T, Uchida H, Hakamada Y, Murakami T, Takahashi M, Kawarasaki H, Hashizume K, Kaneko M, Kobayashi E

    Transplant immunology   Vol. 11 ( 2 ) page: 207-14   2003.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/S0966-3274(03)00008-X

    PubMed

  368. Impact of graft length on surgical damage after intestinal transplantation in rats Reviewed

    S Inoue, K Tahara, Y Sakuma, T Hori, H Uchida, Y Hakamada, T Murakami, M Takahashi, H Kawarasaki, K Hashizume, M Kaneko, E Kobayashi

    TRANSPLANT IMMUNOLOGY   Vol. 11 ( 2 ) page: 207 - 214   2003.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE BV  

    Background: Intestinal grafts greatly affect nutrition and immunology in the host. The growth of the recipient and incidence of graft-versus-host disease depend on graft length. A larger graft may affect the host immune system, but little is known about how the length of the intestinal graft severely affects surgical intervention. We developed a cervical small bowel transplantation (SBT) rat model that minimized technical variations using a cuff method and studied the effects of graft length on surgical damage in SBT. Materials and methods: We transplanted a whole (70 cm) or partial (15 cm) intestine into a syngeneic rat combination of LEW (MHC haplotype: RT1(1)) to LEW and evaluated changes in perioperative hemodynamics and the endogenous endotoxin level. Natural killer (NK) cell activity in the peripheral blood and the immunologic response of the recipient spleen were also studied. Results: In the whole SBT model, body weight loss was more severe than in the segmental SBT model; the rats in the former model often died, while all in the latter survived indefinitely. The systemic blood pressure markedly decreased in the whole SBT group immediately after reperfusion. The proliferative activity of splenic lymphocytes stimulated by concanavalin A was also more severely inhibited in the former model than in the latter postoperatively. NK cell activity in the whole SBT rats declined more severely than the segmental SBT rats 3 days postoperatively. Conclusion: The longer graft severely induced surgical intervention; and influenced host immunosuppression, resulting in the higher mortality in rats undergoing whole SBT. (C) 2003 Elsevier Science B.V. All rights reserved.

    Web of Science

  369. Increase of bile acid production by tacrolimus in the rat liver. Reviewed

    Mizuta K, Kobayashi E, Uchida H, Hishikawa S, Kawarasaki H

    Transplantation proceedings   Vol. 35 ( 1 ) page: 437-8   2003.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  370. Increase of bile acid production by tacrolimus in the rat liver Reviewed

    K Mizuta, E Kobayashi, H Uchida, S Hishikawa, H Kawarasaki

    TRANSPLANTATION PROCEEDINGS   Vol. 35 ( 1 ) page: 437 - 438   2003.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE INC  

    DOI: 10.1016/S0041-1345(02)03794-6

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  371. V-026 ブタ部分小腸移植モデル : VCS クリップを用いた血管吻合法 Reviewed

    吉野 浩之, 山内 仁, 井上 成一朗, 田原 和典, 内田 広夫, 宇野 武治, 水田 耕一, 河原 秀雄, 橋都 浩平, 小林 英司

    日本小児外科学会雑誌   Vol. 39 ( 3 ) page: 241 - 241   2003

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.39.3_241_2

  372. 4. 極低出生体重児のC型食道閉鎖症に対する新しい治療法の試み(セッションIV 低出生体重児)(第19回日本小児外科学会秋季シンポジウム : 先天性食道閉鎖症) Reviewed

    岩中 督, 内田 広夫, 川嶋 寛, 西 明, 工藤 寿美, 佐竹 亮介

    日本小児外科学会雑誌   Vol. 39 ( 6 ) page: 738 - 739   2003

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.39.6_738_3

  373. Short-course methotrexate and long-term acceptance of fully allogeneic rat cardiac grafts: a possible mechanism of tolerance. Reviewed

    Sakuma Y, Xiu D, Uchida H, Hakamata Y, Takahashi M, Murakami T, Nagai H, Kobayashi E

    Transplant immunology   Vol. 10 ( 1 ) page: 49-54   2002.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  374. Short-course methotrexate and long-term acceptance of fully allogeneic rat cardiac grafts: a possible mechanism of tolerance Reviewed

    Sakuma Y, Xiu D, Uchida H, Hakamata Y, Takahashi M, Murakami T, Nagai H, Kobayashi E

    TRANSPLANT IMMUNOLOGY   Vol. 10 ( 1 ) page: 49 - 54   2002.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  375. Combined cuff and suture technique for orthotopic whole intestinal transplantation in rats. Reviewed

    Nakao A, Tahara K, Inoue S, Mizuta K, Takeichi T, Uchida H, Tanaka N, Kobayashi E

    Microsurgery   Vol. 22 ( 3 ) page: 85-90   2002

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/micr.21731

    PubMed

  376. Chronotherapy of sublethal doses of methotrexate on rats allogeneic heart grafts Reviewed International journal

    Xiu D.R, Sakuma Y, Nagai H, To H, Sugimoto K, Fujimura A, Uchida H, Kobayashi E

    Research Communications in Pharmacology and Toxicology   Vol. 7 ( 1-2 ) page: 77 - 85   2002

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  377. Comparison of efficacy and toxicity between Sandimmune® and Neoral® in the cyclosporine-resistant rat allo-pancreas transplantation Reviewed International journal

    Sakuma Y, Nagai H, Sugimoto K.-I, Fujimura A, Murakami T, Uchida H, Hakamata Y, Takahashi M, Kobayashi E

    Research Communications in Pharmacology and Toxicology   Vol. 7 ( 1-2 ) page: 86 - 94   2002

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  378. Blunt Abdominal Injury and Pediatric Trauma Score in Children Reviewed

    Fujino Junko, Ishimaru Yuki, Yamamoto Hideki, Uchida Hiroo, Ikeda Hitoshi

    Journal of the Japanese Society of Pediatric Surgeons   Vol. 38 ( 6 ) page: 826 - 832   2002

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Pediatric Surgeons  

    Purpose : To investigate whether the Pediatric Trauma Score (PTS) correlates with the need for surgery in patients with blunt abdominal injury, a retrospective study was done. Methods : There were 39 injuries of solid organs (liver, spleen and kidneys) and 9 injuries of other organs (duodenum, jejunum and diaphragm). These 48 organ injuries in 42 patients were classified according to the classifications of each organ injury and PTS, treatment and outcome were reviewed. Results and Conclusion : Surgery was done to manage 5 out of the 39 solid organ injuries. PTSs in patients who needed surgery ranged from 1 to 10 (median, 7) and were significantly lower than those with nonoperative management, 4-12 (median, 11)(p=0.004). In the 9 injuries of other organs, PTSs were 4-12 (median, 12) in patients who needed surgery and were not significantly different from the scores 10-12 (median, 10) in patients who were treated nonoperatively. These results indicate that surgical procedures may be necessary in patients with injuries of the liver, the spleen and the kidneys whose PTSs are low. PTS may be important in triage in children with abdominal blunt trauma, although an organspecific grading system should be developed to diagnose the extent of the injury and determine the treatment approach.

    DOI: 10.11164/jjsps.38.6_826

    CiNii Books

    Other Link: http://search.jamas.or.jp/link/ui/2008346366

  379. Surgery: ... An enabling profession? Reviewed

    Lineaweaver, WC

    MICROSURGERY   Vol. 22 ( 4 ) page: 131 - 132   2002

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/micr.21739

    Web of Science

    PubMed

  380. A-16 新生児小腸を用いた移植治療のための基礎的研究 Reviewed

    内田 広夫, 田原 和典, 井上 成一朗, 石丸 由紀, 小林 英司, 池田 均

    日本小児外科学会雑誌   Vol. 38 ( 3 ) page: 422 - 422   2002

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.38.3_422_2

  381. Experimental small bowel transplantation using a newborn intestine in rats: IV. Effect of cold preservation on graft neovascularization. Reviewed

    Uchida H, Tahara K, Takizawa T, Inose K, Yashiro T, Hashizume K, Ikeda H, Takahashi M, Kobayashi E

    Journal of pediatric surgery   Vol. 36 ( 12 ) page: 1805-10   2001.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/jpsu.2001.28843

    PubMed

  382. Experimental small bowel transplantation using a newborn intestine in rats: IV. Effect of cold preservation on graft neovascularization Reviewed

    H Uchida, K Tahara, T Takizawa, K Inose, T Yashiro, K Hashizume, H Ikeda, M Takahashi, E Kobayashi

    JOURNAL OF PEDIATRIC SURGERY   Vol. 36 ( 12 ) page: 1805 - 1810   2001.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:W B SAUNDERS CO  

    Background/Purpose: University of Wisconsin (UW) solution is one of the most superior organ preservation solutions for liver, kidney, and pancreas; however, it still is controversial for intestinal preservation. Here, the authors studied the efficacy of preservation with 2 kinds of solutions, UW and modified TOM (m-TOM) solutions in our experimental newborn intestinal transplantation model. UW solution was used as a standard intracellular and m-TOM solution as an extracellular preservation solution. Lactated ringer (LR) solution was used as a control.
    Methods. Newborn intestine, which were preserved in these solutions for 24 or 48 hours, were transplanted in the subcutaneous spaces of the syngeneic recipients without surgical vascular anastomosis and histologically examined 14 days after grafting. The preserved grafts were evaluated histologically by use of light and electron microscopy just after preservation. The biochemical parameters such as LDH and serotonin also were measured in the supernatants of preservation solutions.
    Results: Fresh newborn grafts were revascularized successfully at a rate of 80% (16 of 20). After 24 hours of preservation, 65% (13 of 20), 75% (15 of 20), and 85% (17 of 20) of the grafts were observed to be revascularized in LR, m-TOM, and UW solutions, respectively. After 48 hours of preservation, 60% (12 of 20), 80% (16 of 20), and 80% (16 of 20) of the grafts also were revascularized in the respective solutions (no statistic difference among the groups). The cold-preservation did not affect the neovascularization of newborn intestine until 48 hours. Histologic findings of the preserved intestine and biochemical analyses showed that UW and m-TOM solutions kept villous architectures of the preserved grafts, however, might be harmful to enterochromaffin cells.
    Conclusion: Long-time preservation of newborn intestine did not interfere with neovascularization and maturation. Copyright (C) 2001 by W.B. Saunders Company.

    Web of Science

  383. High-dose tacrolimus and lengthy survival of the combined rat pancreas/spleen graft in a high-responder combination. Reviewed

    Sakuma Y, Uchida H, Nagai H, Kobayashi E

    Transplant immunology   Vol. 9 ( 1 ) page: 37-42   2001.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  384. High-dose tacrolimus and lengthy survival of the combined rat pancreas/spleen graft in a high-responder combination Reviewed

    Y Sakuma, H Uchida, H Nagai, E Kobayashi

    TRANSPLANT IMMUNOLOGY   Vol. 9 ( 1 ) page: 37 - 42   2001.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE BV  

    Pancreas grafts do not survive for lengthy periods, especially in a high-responder rat combination. Recent data indicated that a combined spleen/pancreas graft protects against acute graft rejection and induces donor-specific tolerance. In this study, we performed a combination spleen/pancreas transplantation using high-dose tacrolimus in a high-responder rat combination of DA (RTla) to LEW(RT1(l)) and induced permanent survival in the few recipient rats. In these recipients, there was no difference in the mixed lymphocyte reaction (MLR) of the recipients when compared with that of the naive LEW splenic cells, but MLR inhibition by the serum from the recipients was significantly decreased. We also performed immunoblotting and detected a protein that has an affinity for the anti-DA class antibody. This protein may be an anti-idiotypic antibody and contribute to donor- and tissue-specific tolerance. (C) 2001 Elsevier Science BN. All rights reserved.

    DOI: 10.1016/S0966-3274(01)00049-1

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  385. Green fluorescent protein-transgenic rat: a tool for organ transplantation research. Reviewed

    Hakamata Y, Tahara K, Uchida H, Sakuma Y, Nakamura M, Kume A, Murakami T, Takahashi M, Takahashi R, Hirabayashi M, Ueda M, Miyoshi I, Kasai N, Kobayashi E

    Biochemical and biophysical research communications   Vol. 286 ( 4 ) page: 779-85   2001.8

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1006/bbrc.2001.5452

    PubMed

  386. Experimental small bowel transplantation using newborn intestine in rats: III. Long-term cryopreservation of rat newborn intestine. Reviewed

    Tahara K, Uchida H, Kawarasaki H, Hasizume K, Kobayashi E

    Journal of pediatric surgery   Vol. 36 ( 4 ) page: 602-4   2001.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/jpsu.2001.22295

    PubMed

  387. Experimental small bowel transplantation using newborn intestine in rats: III. Long-term cryopreservation of rat newborn intestine Reviewed

    K Tahara, H Uchida, H Kawarasaki, K Hasizume, E Kobayashi

    JOURNAL OF PEDIATRIC SURGERY   Vol. 36 ( 4 ) page: 602 - 604   2001.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:W B SAUNDERS CO  

    Background: If long-term organ cryopreservation can be attained, a significant achievement will have been made to address the problem for donor shortage. Fetal intestine has been known to revascularize naturally without vascular anastmosis. The authors have confirmed previously that the newborn intestine also could develop to maturity in the host omentum. Here, the authors examined whether the cryopreserved newborn intestine could revascularize in the syngeneic combination using the 2 different solutions and whether cryopreservation affect their antigenicity in the allogeneic combination.
    Methods: Inbred rat strains of LEW (MHC haplotype; RT1(1)) and BN (RT1(n)) were used. LEW newborn intestinal grafts were stored in RPMI-1640 or University of Wisconsin solution with 10% DEMSO (n = 10 in each group). The grafts were placed into a cold (4 degreesC) preservation solution for 30 minutes and then placed into a freezing chamber and cooled to -80 degreesC at -1 degreesC/min after 12 hours quenched to -180 degreesC in liquid nitrogen for longer than 30 days. Then, the cryopreserved grafts under the 2 different solutions were transplanted syngenicaly (LEW to LEW). The cryopreserved BN grafts also were implanted into the LEW omentum pouch. The allotransplantation was received with a 14-day high-dose course of tacrolimus (0.64 mg/kg, intramuscularly). The grafts were evaluated histologically at 4 weeks after transplantation. Fresh newborn intestines implanted in this syngeneic and allogeneic combination were evaluated as each control group.
    Result: In the syngeneic combination, more than 90% of the mature intestine were obtained. There was no significant difference among the different solution and the fresh group. However, in the allogeneic combination, both fresh and cryo preserved grafts were histologically poor.
    Conclusions: This is the first report showing that long-term cryopreservation was not harmful for neovascularization of newborn intestine. Long-term cryopreservation did not reduce the antigenicity of the newborn intestine.

    Web of Science

  388. Rat auxiliary liver transplantation without portal vein reconstruction: comparison with the portal vein-arterialized model. Reviewed

    Rong Xiu D, Hishikawa S, Sato M, Nagai H, Uchida H, Kobayashi E

    Microsurgery   Vol. 21 ( 5 ) page: 189-95   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  389. Chronopharmacology of oral prednisolone in rats. Reviewed

    Tomizawa N, Uchida H, Xiu DR, To H, Fujimura A, Kobayashi E

    Journal of medicine   Vol. 32 ( 3-4 ) page: 135-51   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  390. Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft. Reviewed

    To H, Xiu DR, Hishikawa S, Uchida H, Sudoh T, Sunaga K, Sugimoto K, Higuchi S, Fujimura A, Kobayashi E

    Research communications in molecular pathology and pharmacology   Vol. 110 ( 5-6 ) page: 319-32   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  391. Orthotopic intestinal transplantation using the cuff method in rats: a histopathological evaluation of the anastomosis. Reviewed

    Nakao A, Ogino Y, Tahara K, Uchida H, Kobayashi E

    Microsurgery   Vol. 21 ( 1 ) page: 12-5   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  392. Simplified method of heterotopic rat heart transplantation using the cuff technique: application to sublethal dose protocol of methotrexate on allograft survival. Reviewed

    Xiu D, Uchida H, To H, Sugimoto K, Kasahara K, Nagai H, Fujimura A, Kobayashi E

    Microsurgery   Vol. 21 ( 1 ) page: 16-21   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  393. Simplified method of heterotopic rat heart transplantation using the cuff technique: Application to sublethal dose protocol of methotrexate on allograft survival Reviewed

    Xiu DR, Uchida H, To H, Sugimoto K, Kasahara K, Nagai H, Fujimura A, Kobayashi E

    MICROSURGERY   Vol. 21 ( 1 ) page: 16 - 21   2001

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  394. Rat auxiliary liver transplantation without portal vein reconstruction: Comparison with the portal vein-arterialized model Reviewed

    Xiu DR, Hishikawa S, Sato M, Nagai H, Uchida H, Kobayashi E

    MICROSURGERY   Vol. 21 ( 5 ) page: 189 - 195   2001

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  395. Orthotopic intestinal transplantation using the cuff method in rats: A histopathological evaluation of the anastomosis Reviewed

    A Nakao, Y Ogino, K Tahara, H Uchida, E Kobayashi

    MICROSURGERY   Vol. 21 ( 1 ) page: 12 - 15   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-LISS  

    Segmental small intestine transplantation (SIT) in rats, using a cuff technique, has achieved a high success rate. However, there have been few reports on the influence of the foreign body reaction to polyethylene cuff on vessel anastomoses and graft after SIT. This study involves the histopathological examination of the site of cuff anastomosis and grafts in the short- and long-term survival of segmental SIT. The data obtained from the suture anastomosis model also served as a control. One week after heterotopic segmental SIT using the cuff technique, orthotopic continuations were carried out in syngeneic combination. Twenty-five of 30 rats surviving &gt;200 days (83.3%) were examined for vessel anastomosis. All arterial anastomoses were patent, but the portovenous anastomoses in 10 grafts (33%) were totally occluded and were associated with the formation of collateral vessels. Histopathological examination demonstrated good patency of the artery and vein anastomotic site in the short term, but granulation, fibrosis, and neovascularization at the anastomosis site surrounding the cuffs in the long-surviving group. However, the grafts appeared to be intact, with normal features of the villi. On the contrary, the site of the sutured anastomosis in the long-survival rats showed no inflammatory reaction. Although a polyethylene cuff caused foreign body reaction, the graft blood supplies were maintained by collateral vessels. Considering the low mortality and high success rate, polyethylene cuff is good for short-term study and an alternative method for long-term SIT experiments. (C) 2001 Wiley-Liss, Inc.

    Web of Science

  396. Rat auxiliary liver transplantation without portal vein reconstruction: Comparison with the portal vein-arterialized model Reviewed

    DR Xiu, S Hishikawa, M Sato, H Nagai, H Uchida, E Kobayashi

    MICROSURGERY   Vol. 21 ( 5 ) page: 189 - 195   2001

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-LISS  

    Auxiliary liver transplantation (ALT) has been reintroduced in clinical cases recently and is now believed to be a viable alternative to orthotopic liver transplantation. To provide a simple rat ALT model for studying the physiological and immunological aspects of the ALT graft, a new ALT was performed, and the comparison between this new model and the portal arterialized one that was reported by other investigators was carried out. At first, we confirmed that liver could tolerate the deprivation of its portal flow well, using a portosystemic shunted rat model. The new rat ALT model, in which the ALT graft obtained its blood inflow only from the hepatic artery, was then performed. Our results demonstrated that 50% of the hepatic artery-alone ALT graft showed almost normal structure histologically at 1 month after grafting, with bile secretion preserved. By contrast, only 8% 1-month graft survival was noted in the portal arterialized group, and all grafts stopped bile secretion 1 week after operation. In conclusion, with arterial blood supply-alone, the ALT graft survived and demonstrated normal bile secretion function for more than 1 month. Portal vein arterialization is not an appropriate way to establish the graft's blood supply if no pressure adjustment measures were taken in advance. (C) 2001 Wiley-Liss, Inc.

    Web of Science

  397. 22. 新生仔小腸を用いた実験的小腸移植の可能性(Session 2. 長期栄養管理のコツ : ここがポイントだ, 小児外科と代謝・栄養, 第 17 回 日本小児外科学会秋季シンポジウム) Reviewed

    内田 広夫, 池田 均, 田原 和典, 小林 英司

    日本小児外科学会雑誌   Vol. 37 ( 6 ) page: 885 - 886   2001

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:特定非営利活動法人 日本小児外科学会  

    DOI: 10.11164/jjsps.37.6_885_2

  398. [Characterization of humoral immunosuppressive factors induced after allogeneic blood transfusion and their application for organ transplantation]. Reviewed

    Uchida H, Tanaka H, Tahara K, Kobayashi E

    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology   Vol. 23 ( 6 ) page: 627-9   2000.12

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    PubMed

  399. Hepatic lymphocyte transplantation in hyperbilirubinemic Gunn rats Reviewed

    Y Yoshida, E Kobayashi, M Nozawa, H Uchida, A Fujimura, T Yamanaka, M Miyata

    EUROPEAN SURGICAL RESEARCH   Vol. 32 ( 4 ) page: 223 - 227   2000.7

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:KARGER  

    Hepatic lymphomyeloid cells (HLCs) are thought to contain liver stem cells. We investigated whether HLCs generated enzyme-producing cells in vivo. HLCs from normal Wistar/Shi rats and rats in which liver ischemia was induced using a portal clamp 4 days previously were studed histopathologically and characterized using flow cytometry. Splenic lymphocytes obtained from these animals were compared as a control. The proliferative activity of HLCs and splenic cells from both groups was also tested by stimulation with concanavalin A. HLCs contained a significantly higher number of NK-T cells and OV6+ cells compared with the splenic cells. The HLCs from rats in which liver ischemia was induced tended to have greater proliferative activity than those from normal rats, while the proliferative activity of splenic lymphocytes was impaired by liver ischemia. The HLCs obtained from Wistar/Shi rats with liver ischemia were then injected into hereditary hyperbilirubinemic Gunn rats to determine whether the HLCs generated enzyme-producing cells. After injection of these stimulated HLCs, the titer of serum bilirubin in the recipient rats was markedly reduced over a long time course (6.80 +/- 0.93 to 4.87 +/- 0.22 mg/dl after 1 month and 3.52 +/- 1.33 mg/dl after 6 months). The results of the present study indicate that HLCs have different populations than splenic cells, and ischemia-reperfusion of the liver increased their proliferative activity. HLC transplantation successfully reduced high bilirubin levels over a long time course. Copyright (C) 2000 S. Karger AG, Basel.

    DOI: 10.1159/000008768

    Web of Science

  400. Effect of erythromycin on ischemia-reperfusion injury of liver in rats. Reviewed

    Ohmori M, Miyashita F, Uchida H, Kitoh Y, Tsuruoka S, Harada K, Sugimoto K, Fujimura A, Kobayashi E

    Transplantation proceedings   Vol. 32 ( 4 ) page: 811-4   2000.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  401. Effect of erythromycin on ischemia-reperfusion injury of liver in rats Reviewed

    Ohmori M, Miyashita F, Uchida H, Kitoh Y, Tsuruoka S, Harada K, Sugimoto K, Fujimura A, Kobayashi E

    TRANSPLANTATION PROCEEDINGS   Vol. 32 ( 4 ) page: 811 - 814   2000.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  402. Mechanisms of immunomodulation induced by blood transfusion: identification of humoral factors. Reviewed

    Uchida H, Tanaka H, Kitoh Y, Yanagisawa K, To H, Tago K, Mizuta K, Fujimura A, Tominaga S, Hashizume K, Kobayashi E

    Transplantation proceedings   Vol. 32 ( 2 ) page: 255-6   2000.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  403. Mechanisms of immunomodulation induced by blood transfusion: Identification of humoral factors Reviewed

    H Uchida, H Tanaka, Y Kitoh, K Yanagisawa, H To, K Tago, K Mizuta, A Fujimura, S Tominaga, K Hashizume, E Kobayashi

    TRANSPLANTATION PROCEEDINGS   Vol. 32 ( 2 ) page: 255 - 256   2000.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE INC  

    DOI: 10.1016/S0041-1345(99)00948-3

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  404. プレドニゾロンの時間薬理学的研究 : 投与時刻による毒性および薬効の検討 Reviewed

    冨沢 直子, 小林 英司, 内田 広夫, 藤 秀人, XIU Dian Rong, 藤村 昭夫

    臨床薬理   Vol. 31 ( 2 ) page: 261 - 262   2000.2

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Clinical Pharmacology and Therapeutics  

    DOI: 10.3999/jscpt.31.261

    CiNii Books

    Other Link: http://search.jamas.or.jp/link/ui/2000211916

  405. Hepatic lymphocyte transplantation in hyperbilirubinemic gunn rats. Reviewed

    Yoshida Y, Kobayashi E, Nozawa M, Uchida H, Fujimura A, Yamanaka T, Miyata M

    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes   Vol. 32 ( 4 ) page: 223-7   2000

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 8768

    PubMed

  406. Detection of membrane-bound and soluble-form MHC class I antigen from rat pancreas/spleen grafts during ongoing rejection. Reviewed

    Kobayashi E, Lord R, Green M, Walker NI, Kamada N, Uchida H, Fujimura A

    Transplantation proceedings   Vol. 31 ( 8 ) page: 3409-13   1999.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  407. Detection of membrane-bound and soluble-form MHC class I antigen from rat pancreas/spleen grafts during ongoing rejection Reviewed

    E Kobayashi, R Lord, M Green, NI Walker, N Kamada, H Uchida, A Fujimura

    TRANSPLANTATION PROCEEDINGS   Vol. 31 ( 8 ) page: 3409 - 3413   1999.12

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER SCIENCE INC  

    DOI: 10.1016/S0041-1345(99)00838-6

    Web of Science

  408. Survival of rats undergoing continuous bile drainage depends on maintenance of circadian rhythm of bile secretion. Reviewed

    Mizuta K, Hishikawa S, Yoshida T, Kobayashi E, Uchida H, Fujimura A, Kawarasaki H, Hashizume K

    Chronobiology international   Vol. 16 ( 6 ) page: 759-65   1999.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  409. Chronopharmacology of tacrolimus in rats: toxicity and efficacy in a mouse-to-rat intestinal transplant model and its pharmacokinetic profile. Reviewed

    Uchida H, Kobayashi E, Ogino Y, Mizuta K, To H, Okabe R, Hashizume K, Fujimura A

    Transplantation proceedings   Vol. 31 ( 7 ) page: 2751-3   1999.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  410. Cyclosporine inhibits transport of bile acid in rats: comparison of bile acid composition between liver and bile. Reviewed

    Mizuta K, Kobayashi E, Uchida H, Ogino Y, Fujimura A, Kawarasaki H, Hashizume K

    Transplantation proceedings   Vol. 31 ( 7 ) page: 2755-6   1999.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  411. Chronotoxicity of mizoribine under repeated administration in the rat. Reviewed

    Hishikawa S, To H, Kobayashi E, Uchida H, Fujimura A

    Transplantation proceedings   Vol. 31 ( 7 ) page: 2765-6   1999.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  412. Experimental intestinal transplantation using mouse fetal intestine in the rat: combination effect of FK 506 with cyclophosphamide. Reviewed

    Uchida H, Kobayashi E, Ogino Y, Mizuta K, Hashizume K, Fujimura A

    Transplantation proceedings   Vol. 31 ( 7 ) page: 2799-800   1999.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  413. Experimental intestinal transplantation using mouse fetal intestine in the rat: Combination effect of FK 506 with cyclophosphamide Reviewed

    Uchida H, Kobayashi E, Ogino Y, Mizuta K, Hashizume K, Fujimura A

    TRANSPLANTATION PROCEEDINGS   Vol. 31 ( 7 ) page: 2799 - 2800   1999.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  414. Chronopharmacology of tacrolimus in rats: Toxicity and efficacy in a mouse-to-rat intestinal transplant model and its pharmacokinetic profile Reviewed

    Uchida H, Kobayashi E, Ogino Y, Mizuta K, To H, Okabe R, Hashizume K, Fujimura A

    TRANSPLANTATION PROCEEDINGS   Vol. 31 ( 7 ) page: 2751 - 2753   1999.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  415. Chronotoxicity of mizoribine under repeated administration in the rat Reviewed

    Hishikawa S, To H, Kobayashi E, Uchida H, Fujimura A

    TRANSPLANTATION PROCEEDINGS   Vol. 31 ( 7 ) page: 2765 - 2766   1999.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  416. Cyclosporine inhibits transport of bile acid in rats: Comparison of bile acid composition between liver and bile Reviewed

    Mizuta K, Kobayashi E, Uchida H, Ogino Y, Fujimura A, Kawarasaki H, Hashizume K

    TRANSPLANTATION PROCEEDINGS   Vol. 31 ( 7 ) page: 2755 - 2756   1999.11

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  417. Influence of tacrolimus on bile acid and lipid composition in continuously drained bile using a rat model - Comparative study with cyclosporine Reviewed International journal

    K Mizuta, E Kobayashi, H Uchida, A Fujimura, H Kawarasaki, K Hashizume

    TRANSPLANT INTERNATIONAL   Vol. 12 ( 5 ) page: 316 - 322   1999.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:SPRINGER VERLAG  

    Cholestatic effects have been reported for cyclosporine (CsA), but information is still limited for tacrolimus (TCR). The purpose of this study was to investigate the influence of TCR on biliary bile acid and lipid composition as compared with CsA, using a continuously bile-drained rat model. Adult male Wistar rats received TCR (0.4 mg/kg, 1 mg/kg, and 4 mg/kg) or CsA (2.5 mg/kg, 10 mg/kg, and 25 mg/kg) by intramuscular injection (i.m.) daily for 10 days,On day 7, the common bile duct of all rats was cannulated, then bile was continuously collected for the following 3 days. Bile flow, bile acid secretion rate (BASR), and biliary lipids secretion were measured for each of the groups. TCR increased bile acid-dependent flow (BADF) but with no statistical significance. However this agent did not influence total bile flow and biliary lipids secretion, while bile acid-independent flow (BAIF) was significantly reduced and bile acid synthesis (mainly cholic acid, CA, synthesis) was increased. In contrast, CsA was cholestatic, showing a tendency to reduce both BADF and BAIF. BASR was dose-dependently suppressed, especially in chenodeoxycholic acid (CDCA). Furthermore biliary lipids secretions were also significantly decreased under a higher dose of CsA, TCR increased BADF with no influence on total bile Row, having a stimulating effect on CA production, although CsA dose-dependently diminishes CDCA production and consequently reduced bile secretion. Our results suggest that TCR is a less effective agent on cholestasis as compared to CsA.

    DOI: 10.1111/j.1432-2277.1999.tb00616.x

    Web of Science

  418. Experimental small bowel transplantation using newborn intestine in rats: II. Revascularization of newborn intestine is independent of vascular endothelial growth factor. Reviewed

    Uchida H, Kobayashi E, Yanagisawa K, Mizuta K, Kitoh Y, Fujimura A, Tominaga S, Kawarasaki H, Hashizume K

    Journal of pediatric surgery   Vol. 34 ( 9 ) page: 1396-400   1999.9

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  419. Experimental small bowel transplantation using newborn intestine in rats: II. Revascularization of newborn intestine is independent of vascular endothelial growth factor Reviewed

    Uchida H, Kobayashi E, Yanagisawa K, Mizuta K, Kitoh Y, Fujimura A, Tominaga S, Kawarasaki H, Hashizume K

    JOURNAL OF PEDIATRIC SURGERY   Vol. 34 ( 9 ) page: 1396 - 1400   1999.9

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  420. Experimental small bowel transplantation using newborn intestine in rats: I. Lipid absorption restored after transplantation of nonvascularized graft. Reviewed

    Uchida H, Yoshida T, Kobayashi E, Mizuta K, Fujimura A, Miyata M, Kawarasaki H, Hashizume K

    Journal of pediatric surgery   Vol. 34 ( 6 ) page: 1007-11   1999.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  421. Experimental small bowel transplantation using newborn intestine in rats: I. Lipid absorption restored after transplantation of nonvascularized graft Reviewed

    Uchida H, Yoshida T, Kobayashi E, Mizuta K, Fujimura A, Miyata M, Kawarasaki H, Hashizume K

    JOURNAL OF PEDIATRIC SURGERY   Vol. 34 ( 6 ) page: 1007 - 1011   1999.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  422. Chronopharmacology for deoxyspergualin: toxicity and efficacy in the rat. Reviewed

    Uchida H, Kobayashi E, Matsuda K, Mizuta K, Sugimoto K, Kawarasaki H, Hashizume K, Fujimura A

    Transplantation   Vol. 67 ( 9 ) page: 1269-74   1999.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  423. Chronopharmacology for deoxyspergualin - Toxicity and efficacy in the rat Reviewed

    Uchida H, Kobayashi E, Matsuda K, Mizuta K, Sugimoto K, Kawarasaki H, Hashizume K, Fujimura A

    TRANSPLANTATION   Vol. 67 ( 9 ) page: 1269 - 1274   1999.5

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  424. Chronopharmacology for deoxyspergualin - Toxicity and efficacy in the rat Reviewed International journal

    H Uchida, E Kobayashi, K Matsuda, K Mizuta, K Sugimoto, H Kawarasaki, K Hashizume, A Fujimura

    TRANSPLANTATION   Vol. 67 ( 9 ) page: 1269 - 1274   1999.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:LIPPINCOTT WILLIAMS & WILKINS  

    Background Deoxyspergualin (DSG), a potent immunosuppressive drug, has been clinically used as a rescue therapy for acute graft rejection. However, DSG has severe adverse effects that limits its use. Here, we examined the optimized therapeutic protocol for DSG using chronopharmacological profiles of it.
    Methods. First, a dosing time-dependent difference in the toxicity and efficacy of DSG was determined using a heterotopic heart transplantation model. Second, chronokinetics of DSG were examined to reveal the mechanism for dosing time-dependent differences in the effect.
    Results. In rats treated with DSG at the active period, bone marrow suppression and damage of small intestine were significantly severe. However, no significant difference was found in cardiac allograft survival and pharmacokinetics according to the timing of drug administration.
    Conclusions. The toxicity of DSG varied with the dosing time, whereas its efficacy did not. The chronopharmacological approach may provide merits for immunosuppressive therapy with DSG in clinical organ transplantation.

    DOI: 10.1097/00007890-199905150-00012

    Web of Science

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  425. Influence of tacrolimus on bile acid and lipid composition in continuously drained bile using a rat model. Comparative study with cyclosporine. Reviewed

    Mizuta K, Kobayashi E, Uchida H, Fujimura A, Kawarasaki H, Hashizume K

    Transplant international : official journal of the European Society for Organ Transplantation   Vol. 12 ( 5 ) page: 316-22   1999

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  426. Effect of immunosuppressants on bile acid kinetics - Comparative study of cyclosporine with tacrolimus Reviewed International journal

    Mizuta K, Kawarasaki H, Hashizume K, Fujimura A, Uchida H, Kobayashi E

    Japanese Pharmacology and Therapeutics   Vol. 27 ( SUPPL. 7 ) page: 93 - 98   1999

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  427. Mechanism of neovascularization in rat newborn organs - Expression of VEGF mRNA and effect of TNP-470 on graft survival Reviewed International journal

    Uchida H, Kobayashi E, Yanagisawa K, Mizuta K, Tominaga S.-I, Hashizume K, Fujimura A

    Biotherapy   Vol. 13 ( 5 ) page: 439 - 441   1999

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    Scopus

    Other Link: http://orcid.org/0000-0002-1818-6697

  428. Survival of rats undergoing continuous bile drainage depends on maintenance of circadian rhythm of bile secretion Reviewed

    Mizuta K, Hishikawa S, Yoshida T, Kobayashi E, Uchida H, Fujimura A, Kawarasaki H, Hashizume K

    CHRONOBIOLOGY INTERNATIONAL   Vol. 16 ( 6 ) page: 759 - 765   1999

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)  

    Web of Science

  429. Experimental small bowel transplantation using newborn intestine in rats - Some immunological studies and considerations for immunological advantage Reviewed

    T Yoshida, H Uchida, E Kobayashi, A Fujimura, M Miyata

    JAPANESE JOURNAL OF TRANSPLANTATION   Vol. 34 ( 4 ) page: 165 - 173   1999

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:JAPANESE SOC TRANSPLANTATION  

    Web of Science

  430. Do immunosuppressants directly affect neutrophils, resulting in protection of the liver against ischemia-reperfusion injury? Reviewed

    Ohmori M, Kobayashi E, Harada K, Kitoh Y, Mizuta K, Uchida H, Ogino Y, Fujimura A

    Transplantation   Vol. 66 ( 7 ) page: 940-1   1998.10

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  431. Dose-dependent reduction of bile secretion in cyclosporine-treated rats. Reviewed

    Mizuta K, Kobayashi E, Uchida H, Fujimura A, Kawarasaki H, Hashizume K

    Transplantation   Vol. 65 ( 5 ) page: 758-9   1998.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  432. Antenatal diagnosis of biliary atresia (type I cyst) at 19 weeks' gestation: differential diagnosis and etiologic implications. Reviewed

    Tsuchida Y, Kawarasaki H, Iwanaka T, Uchida H, Nakanishi H, Uno K

    Journal of pediatric surgery   Vol. 30 ( 5 ) page: 697-9   1995.5

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

▼display all

Books 2

  1. Introduction to Biliary Atresia International journal

    Uchida H, Shirota C, Tainaka T( Role: Joint author)

    Singapore, Springer  2021.4 

     More details

    Responsible for pages:147-156   Language:English Book type:Scholarly book

    DOI: 10.1007/978-981-16-2160-4_22

  2. スタンダード小児内視鏡外科手術 : 押さえておきたい手技のポイント

    山高 篤行, 内田 広夫, 家入 里志, 田口 智章, 奥山 宏臣( Role: Sole author)

    メジカルビュー社  2020  ( ISBN:9784758304672

     More details

    Language:Japanese

    CiNii Books

MISC 111

  1. Urinary Biomarkers Predicting Treatment Outcomes in Neuroblastoma

    Atsushi Narita, Akinari Hinoki, Kazuki Yokota, Motoharu Hamada, Shinsuke Kataoka, Nozomu Kawashima, Hideki Muramatsu, Nobuhiro Nishio, Hiroo Uchida, Yoshiyuki Takahashi

    PEDIATRIC BLOOD & CANCER   Vol. 68   2021.11

     More details

    Language:English   Publishing type:Research paper, summary (international conference)   Publisher:WILEY  

    Web of Science

  2. 内視鏡手術の利点と問題点;合併症、中・長期成績、医療経済、教育 腹腔鏡下葛西術後の胆道閉鎖症に対する生体肝移植の手術成績

    武田 昌寛, 内田 孟, 柳 佑典, 清水 誠一, 福田 晃也, 阪本 靖介, 内田 広夫, 山高 篤行, 笠原 群生

    日本小児外科学会雑誌   Vol. 57 ( 2 ) page: 247 - 247   2021.4

     More details

    Language:Japanese   Publisher:(一社)日本小児外科学会  

  3. 当院における小児胆道閉鎖症の食道胃静脈瘤に対する内視鏡診療経験

    横山 晋也, 石上 雅敏, 本多 隆, 葛谷 貞二, 石津 洋二, 伊藤 隆徳, 内田 広夫, 藤城 光弘

    肝臓   Vol. 61 ( Suppl.1 ) page: A500 - A500   2020.4

     More details

    Language:Japanese   Publisher:(一社)日本肝臓学会  

  4. 血清MMP-7は本邦における胆道閉鎖症の診断に有用か? a pilot study

    坂口 廣高, 小西 健一郎, 石原 潤, 木下 正啓, 橋詰 直樹, 八木 実, 松浦 俊治, 田口 智章, 眞田 幸弘, 田井中 貴久, 内田 広夫, 佐々木 英之, 仁尾 正記, 水落 建輝

    日本小児栄養消化器肝臓学会雑誌   Vol. 33 ( 2 ) page: 155 - 155   2019.12

     More details

    Language:Japanese   Publisher:(一社)日本小児栄養消化器肝臓学会  

  5. 胆道閉鎖症におけるオキシステロール及び胆汁酸分析の有用性 a pilot study

    小西 健一郎, 水落 建輝, 高木 祐吾, 坂口 廣高, 石原 潤, 木下 正啓, 橋詰 直樹, 八木 実, 松浦 俊治, 田口 智章, 眞田 幸弘, 田井中 貴久, 内田 広夫, 佐々木 英之, 仁尾 正記, 藤代 準, 武井 一, 入戸野 博, 木村 昭彦

    日本小児栄養消化器肝臓学会雑誌   Vol. 33 ( 2 ) page: 148 - 148   2019.12

     More details

    Language:Japanese   Publisher:(一社)日本小児栄養消化器肝臓学会  

  6. 反復的に内視鏡的静脈瘤硬化療法を行い、奏効した小児胆道閉鎖症の一例

    横山 晋也, 石上 雅敏, 本多 隆, 葛谷 貞二, 石津 洋二, 伊藤 隆徳, 城田 千代栄, 内田 広夫, 藤城 光弘

    日本門脈圧亢進症学会雑誌   Vol. 25 ( 3 ) page: 143 - 143   2019.9

     More details

    Language:Japanese   Publisher:(一社)日本門脈圧亢進症学会  

  7. 胆道閉鎖症における食道胃静脈瘤の診断に対するshear wave elastographyの有用性

    横山 晋也, 石上 雅敏, 本多 隆, 葛谷 貞二, 石津 洋二, 伊藤 隆徳, 藤城 光弘, 田中 裕次郎, 檜 顕成, 城田 千代栄, 田井中 貴久, 牧田 智, 谷 有希子, 田中 智子, 内田 広夫

    日本小児外科学会雑誌   Vol. 55 ( 3 ) page: 539 - 539   2019.5

     More details

    Language:Japanese   Publisher:(一社)日本小児外科学会  

  8. 医工連携による生分解性外科手術用デバイスの研究開発

    天野 日出, 檜 顕成, 花田 幸太郎, 三宅 行一, 田井中 貴久, 城田 千代栄, 住田 亙, 横田 一樹, 村瀬 成彦, 大島 一夫, 千馬 耕亮, 藤代 準, 田中 裕次郎, 内田 広夫

    日本外科学会定期学術集会抄録集   Vol. 119回   page: SP - 5   2019.4

     More details

    Language:Japanese   Publisher:(一社)日本外科学会  

  9. 胆道閉鎖症における非侵襲的な門脈圧亢進症の診断能に関する検討

    横山 晋也, 石津 洋二, 伊藤 隆徳, 葛谷 貞二, 本多 隆, 石上 雅敏, 藤城 光弘, 城田 千代栄, 内田 広夫

    肝臓   Vol. 60 ( Suppl.1 ) page: A341 - A341   2019.4

     More details

    Language:Japanese   Publisher:(一社)日本肝臓学会  

  10. 静電植毛電極を用いた多誘導心電図測定ウェア

    竹下俊弘, 吉田学, 竹井祐介, 大内篤, 檜顕成, 内田広夫, 小林健

    バイオメカニクス研究センター&エレクトロニクス実装学会九州支部合同研究会   Vol. 7th (CD-ROM)   2019

     More details

  11. 静電植毛技術を用いた心電図測定用立体ドライ電極の作製と応用

    竹下俊弘, 吉田学, 竹井祐介, 大内篤, 檜顕成, 内田広夫, 小林健

    エレクトロニクス実装学会講演大会講演論文集(CD-ROM)   Vol. 33rd   2019

     More details

  12. Development of ECG measuring wear using cubic dry electrode

    竹下俊弘, 吉田学, 竹井裕介, 大内篤, 小林健, 檜顕成, 内田広夫

    センサ・マイクロマシンと応用システムシンポジウム(CD-ROM)   Vol. 36th   2019

     More details

  13. 小児内視鏡外科手術の教育についての工夫と提言 小児高難度内視鏡手術の技術習得には疾患特異的模擬臓器モデルによるOff the Job Trainingは必須である

    出家 亨一, 内田 広夫, 増山 秀徳, 檜 顕成, 石丸 哲也, 藤雄木 亨真, 田中 智子, 大島 一夫, 横田 一樹, 村瀬 成彦, 住田 亙, 田井中 貴久, 城田 千代栄, 藤代 準, 田中 裕次郎

    日本内視鏡外科学会雑誌   Vol. 23 ( 7 ) page: PD6 - 4   2018.12

     More details

    Language:Japanese   Publisher:(一社)日本内視鏡外科学会  

  14. インドシアニングリーン内包高分子ミセルを用いた小児悪性固形腫瘍への応用展開

    高橋 正貴, 守本 祐司, 檜 顕成, 小関 英一, 原 功, 藤代 準, 野村 信介, 佐藤 あやの, 高山 英次, 内田 広夫

    日本レーザー医学会誌   Vol. 39 ( 3 ) page: 225 - 225   2018.9

     More details

    Language:Japanese   Publisher:(NPO)日本レーザー医学会  

    J-GLOBAL

  15. 神経芽腫に対する新規治療法の開発 インドシアニングリーン内包生分解性ナノ粒子を用いた光温熱療法

    高橋 正貴, 守本 祐司, 檜 顕成, 小関 英一, 原 功, 藤代 準, 野村 信介, 田井中 貴久, 佐藤 あやの, 高山 英次, 内田 広夫

    日本小児外科学会雑誌   Vol. 54 ( 3 ) page: 684 - 684   2018.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  16. 少ない経験数にも関わらず内視鏡手術を安全に行うための生体質感臓器モデルを用いたトレーニングの有用性

    出家 亨一, 内田 広夫, 増山 秀徳, 檜 顕成, 石丸 哲也, 藤代 準, 城田 千代栄, 田中 裕次郎

    日本小児外科学会雑誌   Vol. 54 ( 3 ) page: 649 - 649   2018.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  17. 生分解性新規マグネシウム合金を用いた体内残存異物とならないステープルの開発

    天野 日出, 檜 顕成, 花田 幸太郎, 田井中 貴久, 城田 千代栄, 住田 亙, 横田 一樹, 村瀬 成彦, 大島 一夫, 白月 遼, 千馬 耕亮, 藤代 準, 田中 裕次郎, 内田 広夫

    日本小児外科学会雑誌   Vol. 54 ( 3 ) page: 680 - 680   2018.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  18. 小児内視鏡手術支援のための患者固有データを用いたトロッカーシミュレーションは非常に効果的である

    出家 亨一, 内田 広夫, 檜 顕成, 石丸 哲也, 横田 一樹, 村瀬 成彦, 城田 千代栄, 田井中 貴久, 田中 裕次郎, 藤代 準

    日本内視鏡外科学会雑誌   Vol. 22 ( 7 ) page: EP075 - 02   2017.12

     More details

    Language:Japanese   Publisher:(一社)日本内視鏡外科学会  

  19. 体内残存異物とならない亜鉛合金を用いた内視鏡外科手術用デバイスの開発

    天野 日出, 檜 顕成, 三宅 行一, 田井中 貴久, 城田 千代栄, 住田 亙, 横田 一樹, 村瀬 成彦, 大島 一夫, 白月 遼, 千馬 耕亮, 藤代 準, 田中 裕次郎, 内田 広夫

    日本内視鏡外科学会雑誌   Vol. 22 ( 7 ) page: SF023 - 02   2017.12

     More details

    Language:Japanese   Publisher:(一社)日本内視鏡外科学会  

  20. 小児内視鏡外科手術のためのOn the job training回避を目的とした統合的トレーニングシステムの開発

    出家 亨一, 内田 広夫, 檜 顕成, 石丸 哲也, 城田 千代栄, 横田 一樹, 村瀬 成彦, 田井中 貴久, 田中 裕次郎, 藤代 準

    日本コンピュータ外科学会誌   Vol. 19 ( 4 ) page: 288 - 288   2017.10

     More details

    Language:Japanese   Publisher:(一社)日本コンピュータ外科学会  

  21. 小児内視鏡手術支援のための患者特異的バーチャルリアリティーシミュレーションシステムの開発

    出家 亨一, 内田 広夫, 檜 顕成, 石丸 哲也, 藤代 準, 城田 千代栄, 田中 裕次郎

    日本小児外科学会雑誌   Vol. 53 ( 3 ) page: 783 - 783   2017.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  22. 小児内視鏡外科手術におけるナビゲーション・シミュレーション 小児外科医にとって手術ロボットは有用か 小児胸腔モデルを用いた縫合シミュレーション

    高澤 慎也, 石丸 哲也, 檜 顕成, 原田 香奈子, 出家 亨一, 藤代 準, 杉田 直彦, 光石 衛, 岩中 督, 内田 広夫

    日本内視鏡外科学会雑誌   Vol. 21 ( 7 ) page: WS7 - 1   2016.12

     More details

    Language:Japanese   Publisher:(一社)日本内視鏡外科学会  

  23. 小児外科医が手術ロボットを使用したらどうなる?―小児胸腔モデルを用いた縫合シミュレーション―

    高澤慎也, 石丸哲也, 原田香奈子, 出家亨一, 藤代準, 杉田直彦, 光石衛, 岩中督, 内田広夫

    第29回日本内視鏡外科学会総会 WS7-1     2016.12

  24. [THE CURRENT SITUATION AND THE DESIRED FUTURE OF PEDIATRIC MINIMALLY INVASIVE SURGERY]. Invited Reviewed

    Uchida H

    Nihon Geka Gakkai zasshi   Vol. 117 ( 4 ) page: 324-8   2016.7

     More details

    Language:Japanese  

    PubMed

  25. 肥厚性幽門狭窄症 (特集 退院から1カ月健診までの新生児対応) -- (見落としてはならない疾患)

    村瀬 成彦, 内田 広夫

    周産期医学   Vol. 46 ( 1 ) page: 63 - 65   2016.1

     More details

    Language:Japanese   Publisher:東京医学社  

    CiNii Books

    Other Link: http://search.jamas.or.jp/link/ui/2016139544

  26. 横隔膜ヘルニアの術式による検討

    新井 真理, 岩中 督, 杉山 正彦, 藤代 準, 石丸 哲也, 佐藤 かおり, 吉田 真理子, 出家 亨一, 宮川 亨平, 魚谷 千都絵, 加藤 怜子, 川嶋 寛, 内田 広夫

    日本小児外科学会雑誌   Vol. 51 ( 6 ) page: 1119 - 1119   2015.10

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  27. Children's Oncology Groupの神経芽腫中リスク群に対して腫瘍切除は必要か?

    天野 日出, 内田 広夫, 川嶋 寛, 田中 裕次郎, 東間 未来, 藤雄木 亨真, 鈴木 啓介, 森田 香織, 森 麻希子, 康 勝好, 岸本 宏志, 小熊 栄二

    日本小児外科学会雑誌   Vol. 51 ( 3 ) page: 481 - 481   2015.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  28. 新生児・乳児領域における内視鏡手術の展開 当院における胸腔鏡下食道閉鎖症根治術・胸腔鏡下肺切除の経験と今後の展開

    川嶋 寛, 田中 裕次郎, 東間 未来, 益子 貴行, 出家 亨一, 藤雄木 亨真, 天野 日出, 内田 広夫

    日本周産期・新生児医学会雑誌   Vol. 51 ( 1 ) page: 9 - 11   2015.5

     More details

    Language:Japanese   Publisher:(一社)日本周産期・新生児医学会  

    1997年1月から2014年3月までに行われた新生児に対する胸腔鏡下食道閉鎖症根治術17例について検討した。C型11例には一期的根治術を行い、開胸移行は1例、術後合併症は吻合不全2例と吻合部狭窄1例であった。C型4例、A型1例、D型1例には多期的根治術を行い、開胸移行は1例、術後合併症は吻合不全5例と吻合部狭窄3例であった。また、同時期に行われた2歳以下の胸腔鏡下肺切除術11例について検討した。原疾患はCCAM 5例、肺分画症5例、気管支狭窄1例で、術式は肺葉切除10例、区域切除1例、肺外分画肺切除1例であり、術後合併症は無気肺、肺炎、皮下気腫、胸水貯留、創感染などであった。胸腔鏡下食道閉鎖症根治術、胸腔鏡下肺切除術はいずれも術式が標準化されており、小児においても安全に施行可能と思われた。

  29. 腹腔鏡下肝生検の検討

    益子 貴行, 内田 広夫, 川嶋 寛, 田中 裕次郎, 出家 亨一, 鍵本 聖一, 越永 從道

    日本小児外科学会雑誌   Vol. 51 ( 3 ) page: 601 - 601   2015.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  30. 【エンジョイ!症例報告:手術・治療の工夫(I)】Long gap C型食道閉鎖症術後気管食道瘻再開通に対する胸腔鏡根治術

    出家 亨一, 内田 広夫, 川嶋 寛, 田中 裕次郎, 益子 貴行, 天野 日出, 岩中 督

    小児外科   Vol. 47 ( 1 ) page: 23 - 27   2015.1

     More details

    Language:Japanese   Publisher:(株)東京医学社  

    生後4ヵ月男児。出生直後よりチアノーゼと呼吸不全を発症、X線像にてcoil up signを認め、食道閉鎖症の診断にて日齢0に前医より転院となった。所見より約4椎体のgapがあるC型食道閉鎖症に対して日齢1に胸腔鏡食道閉鎖根治術を施行するも術後縫合不全となり、保存的治療にて改善が得られたものの、術後4週目の食道造影にて吻合部狭窄、気管食道瘻(TEF)の再発、胃食道逆流(GER)が認められた。以後、GERに伴った徐脈、嘔吐や呼吸不全が頻回に出現したため日齢37に腹腔鏡下Collis-Nissen噴門形成術をはじめ、胃瘻造設術の施行により徐脈や嘔吐などの症状は消失した。一方、TEFに対しては食道の再開通部口側に食道チューブを留置し、持続吸引するなど保存的加療を試みたがTEFの閉鎖は得られず、保存的加療は断念して体重が3.4kgに増加した日齢122に胸腔鏡によるTEF根治術が施行された。その際、術中TEFとその周囲組織との間に癒着が認められたもののTEF自体の同定は比較的容易であり、癒着を剥離していくと瘻孔部分は周囲よりも硬い組織で覆われていた。このことはTEF同定の一助となった。尚、術後は34日目経過の食道造影で明らかな縫合不全や吻合部狭窄、TEFの再発は認められず、38日目より患者は経口摂取訓練を開始、術後78日目に胃瘻を閉鎖した。経過は良好で退院は術後85日目となった。

  31. 回盲部狭窄を来した腸管ベーチェット病疑いに対して待機的に単孔式腹腔鏡下回盲部切除を行った13歳女児例

    寺脇 幹, 古村 眞, 佐竹 亮介, 小高 哲郎, 森岡 真吾, 内田 広夫

    日本内視鏡外科学会雑誌   Vol. 19 ( 7 ) page: 773 - 773   2014.10

     More details

    Language:Japanese   Publisher:(一社)日本内視鏡外科学会  

  32. CLINICAL TOPICS : Thoracoscopic Repair of Esophageal Atresia With or Without Tracheoesophageal Fistula, Pursuing Development of an Innovative Treatment

      Vol. 62 ( 1 ) page: 93 - 99   2014.6

     More details

  33. 【単孔式内視鏡手術】単孔式虫垂切除術

    出家 亨一, 内田 広夫, 川嶋 寛

    小児外科   Vol. 46 ( 3 ) page: 247 - 251   2014.3

     More details

    Language:Japanese   Publisher:(株)東京医学社  

  34. 【小児外傷性臓器損傷の治療戦略と手術のポイント】膵損傷の治療戦略と手術ポイント 小児IIIb型症例に対する内視鏡治療の可能性

    出家 亨一, 内田 広夫, 糸井 隆夫

    小児外科   Vol. 45 ( 9 ) page: 990 - 993   2013.9

     More details

    Language:Japanese   Publisher:(株)東京医学社  

  35. 消化管穿孔を生じた極低出生体重児の神経学的予後 非外科疾患児との比較

    田中 裕次郎, 内田 広夫, 川嶋 寛, 佐藤 かおり, 高澤 慎也, 出家 亨一, 菅野 啓一, 清水 正樹

    日本小児外科学会雑誌   Vol. 49 ( 3 ) page: 613 - 613   2013.5

     More details

    Language:Japanese   Publisher:(NPO)日本小児外科学会  

  36. 臍帯ヘルニ