Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.12659/AJCR.938723

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PURPOSE: Rectal prolapse after radical surgery for anorectal malformations (ARMs) is a common postoperative complication that causes bleeding and stenosis, and sometimes requires surgical treatment. Different surgical techniques have been reported, but most are associated with high recurrence rates and a long postoperative stay. We performed the hemi-circumferential mucosal resection and anastomosis procedure (HCMR) to preserve anal muscle and anal function. Here, we report the success of our minimally invasive surgical approach to correct rectal prolapse in patients with ARMs. METHODS: The subjects of this retrospective review were patients who underwent HCMR for rectal prolapse after radical surgery for ARMs between January, 2014 and August, 2021. HCMR involves rectal mucosal resection without muscle plication. RESULTS: A collective 15 HCMR procedures were performed in 10 patients. The median age at repair was 1.8 years (range, 10 months-18 years). The median operation time and postoperative length of stay were 46 min (range, 17-85 min) and 3 days (range, 1-7 days), respectively. The median postoperative observation period was 3 years 4 months (range, 8 months-7 years 10 months) and no complications or recurrences were observed. CONCLUSIONS: HCMR is a safe and effective surgical treatment for rectal prolapse after radical operation for ARMs, which is minimally invasive and preserves rectal muscle and function.

DOI： 10.1007/s00595-022-02611-7

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PURPOSE: This study aimed to evaluate the learning curve of thoracoscopic repair of tracheoesophageal fistula (TEF) by a single surgeon using a cumulative sum (CUSUM) analysis. METHODS: Prospective clinical data of consecutive Gross type-C TEF repairs performed by a pediatric surgeon from 2010 to 2020 were recorded. CUSUM charts for anastomosis and operating times were generated. The learning curves were compared with the effect of accumulation based on case experience. RESULTS: For 33 consecutive cases, the mean operative and anastomosis times were 139 ± 39 min and 3137 ± 1110 s, respectively. Significant transitions beyond the learning phase for total operating and anastomosis times were observed at cases 13 and 17. Both the total operating time and anastomosis time were significantly faster in the proficiency improvement phase than in the initial learning phase. Postoperative complications significantly decreased after the initial anastomosis learning phase but not after the initial total operating learning phase. CONCLUSIONS: Thoracoscopic repair of TEF is considered safe and feasible after 13 cases, where the surgeon can improve their proficiency with the total operation procedure, and 17 cases, which will enable the surgeon to achieve proficiency in anastomosis. Postoperative complications significantly decreased after gaining familiarity with the anastomosis procedure through the learning phase.

DOI： 10.1007/s00595-023-02687-9

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PURPOSE: Necrotizing enterocolitis (NEC) causes fatal intestinal necrosis in neonates, but its etiology is unknown. We analyzed the intestinal immune response to NEC. METHODS: Using single-cell RNA sequencing (scRNA-seq), we analyzed the gene expression profiles of intestinal immune cells from four neonates with intestinal perforation (two with NEC and two without NEC). Target mononuclear cells were extracted from the lamina propria of the resected intestines. RESULTS: In all four cases, major immune cells, such as T cells (15.1-47.7%), B cells (3.1-19.0%), monocytes (16.5-31.2%), macrophages (1.6-17.4%), dendritic cells (2.4-12.2%), and natural killer cells (7.5-12.8%), were present in similar proportions to those in the neonatal cord blood. Gene set enrichment analysis showed that the MTOR, TNF-α, and MYC signaling pathways were enriched in T cells of the NEC patients, suggesting upregulated immune responses related to inflammation and cell proliferation. In addition, all four cases exhibited a bias toward cell-mediated inflammation, based on the predominance of T helper 1 cells. CONCLUSION: Intestinal immunity in NEC subjects exhibited stronger inflammatory responses compared to non-NEC subjects. Further scRNA-seq and cellular analysis may improve our understanding of the pathogenesis of NEC.

DOI： 10.1007/s00383-023-05461-7

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

We report an extremely rare case of a right Bochdalek hernia with a sac, in which the retroperitoneal and intra-abdominal organs prolapsed into the thoracic cavity at the same time. The patient was a 7-month-old female with no comorbidities. She presented with cough and fever, and chest radiography revealed a right diaphragmatic hernia. Computed tomography showed that the right kidney, intestine, colon, and liver had prolapsed into the thoracic cavity. The patient underwent thoracoscopic surgery, which showed that the abdominal and retroperitoneal organs prolapsed into the thoracic cavity through the Bochdalek hernia. The herniated organs were spontaneously reduced using thoracoscopic insufflation. The defect hole was closed with artificial mesh. We adopted a thoracoscopic approach, in terms of easy reduction of herniated organs and accurate evaluation of the hernia orifice, which was useful.

DOI： 10.1111/ases.13139

Web of Science

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00595-023-02652-6

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: We encountered two cases of a new type of retroperitoneal hernia. We herein report the unique features of these cases. CASE PRESENTATION: Case 1: A Japanese girl was born at a gestational age of 37 weeks, weighing 2550 g. She underwent laparotomic left diaphragmatic hernia repair for a left Bochdalek hernia at the age of one day. The postoperative course was uneventful; however, chest radiography at the age of 35 days revealed bowel gas in the mediastinum, while computed tomography exhibited intestinal prolapses from the medial side of the mesh into the thoracic cavity. Reoperation was performed at the age of 77 days, showing that the defect hole was not at the diaphragm but in the absence of retropancreatic fascia, which was connected to the posterior mediastinum from the supramesocolic space. The mediastinum space was closed with a suturing spine and artificial mesh, and the defect hole in the pancreatic body was sutured. Case 2: A Japanese boy was born at a gestational age of 40 weeks, weighing 3502 g. He was diagnosed with a left diaphragmatic hernia at birth and underwent laparotomy at the age of two days. Operative findings showed no defect hole in the diaphragm, and no intestine was observed in the abdominal cavity. After close observation of the abdominal cavity, the intestine was found around the pancreatic body, and manual reduction of the intestine was performed. The defect hole existed in the absence of the retropancreatic fascia, which was connected to the extra-pleural space. The defect hole in the pancreatic body was sutured and closed with a non-absorbable thread. CONCLUSIONS: We assumed that our cases were a new type of retroperitoneal hernia, which we named "retropancreatic fascia hernia".

DOI： 10.1186/s40792-023-01586-y

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: Esophagogastric varices (EGVs) may develop as a result of portal hypertension in children with biliary atresia (BA). Although endoscopic injection sclerotherapy (EIS) with ethanolamine oleate (EO) is reported useful for children, risk factors associated with the presence of high-risk EGVs after treatment remain unknown. METHODS: The subjects were BA patients under 15 years of age who underwent EO-EIS. We retrospectively reviewed a total of 28 treatment sessions of EGVs with red signs and those larger than F2, which were considered to be at high risk of bleeding. Survival analysis was performed for the presence of high-risk EGVs at the time of follow-up endoscopy as the occurrence of an event. RESULTS: Univariate analysis showed a significantly increased risk of the presence of high-risk EGVs post-EO-EIS in patients with increased liver stiffness (LS) and Mac-2 binding protein glycan isomer (M2BPGi), with hazard ratios of 1.48 and 1.15, respectively. The median presence-free period was significantly shorter in the LS ≥ 2.8 m/sec patients than in those with LS < 2.8 m/sec (189 vs. 266 days). Similarly, the median presence-free period was significantly shorter in patients with M2BPGi ≥ 4.0 than in those with M2BPGi < 4.0 (182 vs. 203 days). The results of multivariate analysis revealed that the risk of the presence of high-risk EGVs was significantly higher only in the high-LS group, with a hazard ratio of 2.76. CONCLUSIONS: Increased LS is associated with risk of the presence of high-risk EGVs following EO-EIS in children with BA. (246 words).

DOI： 10.1111/ped.15454

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.3389/fped.2023.1175231

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.3389/fped.2023.1220393

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.3389/fped.2023.1149515

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: The urachus is an embryonic structure that connects the bladder to the allantois during early embryonic development. Occasionally, it fails to disappear at birth, leading to a case of urachal remnant (UR). This study aimed to determine whether our policy for selecting an appropriate UR resection approach is valid. We performed preoperative imaging to examine whether UR continued toward the bladder apex. If so, the UR and bladder apex were excised using the trans-umbilical approach, in addition to laparoscopy, if necessary. If preoperative imaging indicated that the UR ended near the umbilicus, the UR from the umbilicus to the duct end was resected. Pathological evaluations were performed to determine the appropriateness of the surgical approach indicated by preoperative imaging. METHODS: We retrospectively reviewed pediatric patients with UR who underwent surgery between 2015 and 2021. Their background characteristics and surgical outcomes were evaluated. RESULTS: Twenty patients with UR were included (median age, 7 [interquartile range, 2-10.25] years). UR continued toward the bladder apex in 10 patients and ended near the umbilicus in 10 patients. Urachus tissue at the bladder site was observed when the UR and bladder apex were excised. When UR was resected from the umbilicus to the duct end, urachus tissue was not pathologically detected at the resection margin. CONCLUSION: Our policy results in complete resection without excessive surgical invasion.

DOI： 10.1186/s12894-022-01153-x

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: Like esophageal varices, cardiac varices are often treated with endoscopic variceal ligation (EVL). However, we previously reported that EVL for cardiac varices may be associated with a high risk of rebleeding from the ulcer if the O-ring spontaneously drops off early. The efficacy and safety of para-variceal endoscopic injection sclerotherapy (EIS) with polidocanol for the treatment of cardiac varices in children and adolescents were evaluated. METHODS: Eleven patients under 18 years of age with portal hypertension who underwent para-variceal EIS with polidocanol for cardiac varices with red signs, which were considered to be at high risk of bleeding, were retrospectively reviewed. RESULTS: One session of para-variceal polidocanol-EIS was performed for each of the 11 patients. One patient experienced temporary hypoxia due to aspiration of saliva when the tracheal intubation tube was removed after the procedure but recovered by endotracheal suctioning; there were no other adverse events. In six of the eight cases in which efficacy could be evaluated, eradication of cardiac varices was achieved. CONCLUSION: Para-variceal polidocanol-EIS may be considered instead of EVL for small cardiac varices with red signs in pediatric patients with cardiac varices.

DOI： 10.1016/j.arcped.2022.11.016

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: Omphalocele is a congenital abdominal wall defect of the umbilical cord insertion site. A giant omphalocele, with a fascial defect > 5 cm in diameter and/or containing > 50% of the liver within the hernia sac, can be challenging for pediatric surgeons. Recently, negative pressure wound therapy has been reported as an effective management for giant omphaloceles; however, it is not recommended for an infected wound with necrotic tissue as it may exacerbate infection. We adopted negative pressure wound therapy with irrigation and dwell time (NPWTi-d) for a case of a ruptured giant omphalocele. Artificial membranes, followed by artificial dermis, were used to promote fibrous capsule formation, and then NPWTi-d was used to promote granulation while controlling infection. However, studies have not been conducted regarding NPWTi-d for ruptured giant omphaloceles; hence, we present our treatment experience with NPWTi-d for a giant omphalocele. CASE PRESENTATION: The patient was a boy born at 38 weeks and 3 days of gestation, weighing 1896 g. He was diagnosed with a ruptured giant omphalocele with a total liver and intestine defect hole of 10 cm × 10 cm. The patient underwent silo placement using an artificial mesh, followed by plicating the artificial mesh at 4 days of age. The herniated viscera were gradually reduced into the abdominal cavity; however, the defect size was still large. Hence, a collagen-based artificial dermis was patched on the defect hole. After creating a fresh and smooth granulated tissue, NPWTi-d was applied at 33 days of age to promote granulation and control infection. We used the 3 M™ V.A.C.® Ulta Therapy Unit with 3 M™ VeraFlo™ therapy. NPWTi-d was stopped at 60 days of age when the granulation tissue was well formed including at the artificial dermis site. The wound was managed with prostandin ointment and appropriate debridement, resulting in complete epithelialization at 5 months of age. CONCLUSIONS: Artificial membranes followed by artificial dermis were used to promote a fibrous capsule and artificial dermis granulation, which protects against organ damage. NPWTi-d achieved better control of infection and promoted wound healing. NPWTi-d combined with artificial dermis can effectively treat ruptured giant omphaloceles.

DOI： 10.1186/s12887-022-03755-8

Web of Science

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

Purpose: A laparoscopic approach for malrotation is feasible and safe in hemodynamically stable neonates without intestinal necrosis; however, volvulus is associated with recurrence and conversion. We developed a novel approach using a laparoscopic duodenal-caudal detachment method to perform the Ladd procedure for neonates with volvulus under the limited view of laparoscopy. This study presents the results, effectiveness, and details of the method. Materials and Methods: In the laparoscopic duodenal-caudal detachment method, we first detached the adhesions around the duodenum, including the Ladd's band. After the adhesions were completely removed, the duodenum was freely drawn caudally, leading to the release of torsion. We retrospectively reviewed the medical records of patients who underwent surgery for malrotation of the volvulus at 30 days of age between January 2014 and September 2021. Results: Seven neonates underwent the laparoscopic duodenal-caudal detachment method and 13 underwent the open Ladd procedure. The new technique was performed in all 7 patients, and there were no conversions or recurrences. The operation time was significantly longer in the laparoscopic procedure group (55 minutes versus 111 minutes; P < .01). Conclusions: Our detorsion method, involving an initial incision of the Ladd's band, is safe and effective for neonates and may lead to an improvement in the conversion rates.

DOI： 10.1089/lap.2022.0390

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

This paper describes the fabrication and fundamental evaluation of the cubic flocked electrode (CFE), which is a dry electrode that is fabricated using electrostatic flocking technology. The development of a wearable multi-lead electrocardiogram (ECG) measurement device using the CFE is also reported. To enable the measurement of ECG signals with sufficient quality for medical applications, the occurrence of motion artifacts (MAs) is the most important problem to be overcome. Therefore, it is necessary to stabilize the contact between the patient's skin and the dry electrode. Because the CFE developed in this work offers both contact stability and flexibility, it is expected to enable ECG measurements with low MA levels. In this study, it is demonstrated that the number of MAs caused by respiration can be reduced when the CFE contact is made at a contact pressure of approximately 500 Pa using MA evaluation equipment that was developed in-house. Additionally, a wearable multi-lead ECG is designed and fabricated based on this contact pressure (500 Pa). The results of the demonstration experiment show that the ECG measurements are successful to the same extent as a conventional medical device.

DOI： 10.1038/s41598-022-24043-6

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

This study aimed to evaluate the safety and effectiveness of circumumbilical incision (CUI) for neonates requiring intestinal anastomosis. Seventy neonates requiring intestinal anastomosis at our institution between 2003 and 2020 were included in this retrospective case-control study. Patients were classified into the CUI (25 patients: 36%) and transverse incision (TI) groups (45 patients: 64%). Postoperative complications and surgical outcomes were compared between the two groups. Intestinal perforation at the non-anastomotic site occurred significantly more often in the CUI group than in the TI group (3 patients: 12%, and 0 patients: 0%, respectively (p = 0.042)). There were no between-group differences regarding anastomotic leakages, anastomotic strictures, time to enteral feeding, operative time, and blood loss. Neonatal intestinal surgery employing CUI might be associated with increased intestinal perforation at the non-anastomotic site. Hesitating to enlarge the skin incision to maintain favorable cosmetic outcomes might cause severe injury to the delicate neonatal intestine during the surgical procedure owing to the restricted surgical field. When performing CUI, we suggest that the skin incision should be extended without hesitation whenever there is difficulty in manipulating the intestine.

DOI： 10.18999/nagjms.84.4.716

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：東京医学社  

DOI： 10.24479/ps.0000000254

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2022.0152

PubMed

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ases.13133

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：東京医学社  

DOI： 10.24479/ps.0000000234

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)   Publisher：東京医学社  

DOI： 10.24479/ps.0000000238

CiNii Research

Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-022-05243-7

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-022-05230-y

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-022-05235-7

PubMed

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/jhbp.1235

Web of Science

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ases.13119

PubMed

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ases.13116

Web of Science

PubMed

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：日本メディカルセンター  

DOI： 10.19020/cg.0000002333

CiNii Research

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12893-022-01738-1

PubMed

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-022-05125-y

Web of Science

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00464-022-09185-y

PubMed

Authorship：Last author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12887-022-03207-3

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：東京医学社  

DOI： 10.24479/pm.0000000090

CiNii Research

Authorship：Last author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00464-022-09132-x

Web of Science

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/hepr.13753

Web of Science

PubMed

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.84.1.148

Web of Science

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.4240/wjgs.v14.i1.56

PubMed

Authorship：Last author   Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.4103/jmas.JMAS_98_21

Web of Science

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

A tracheoesophageal fistula (TEF) recurs in approximately 2%-13% of cases of esophageal atresia with TEF that are treated surgically. Currently, there is no consensus on the most effective treatment to prevent recurrent TEF (RTEF). Herein, we present a patient with type C esophageal atresia who underwent thoracoscopic esophago-esophageal anastomosis and TEF repair at 2 days old. However, RTEFs were observed at ages 3, 6, and 11 months, and thoracoscopic TEF repairs using a pleural patch, fascia lata graft, and pectoralis major myocutaneous (PMMC) flap were performed, respectively. A fourth recurrence led to mediastinitis, shock liver, disseminated intravascular coagulopathy, and a compromised respiratory status. Hence, laparoscopic esophageal transection was first performed to improve the respiratory condition by preventing the regurgitation of gastric contents. Once the patient was stable, a subtotal esophageal resection with TEF closure followed by gastric tube reconstruction was performed. In conclusion, we encountered a case of refractory RTEF that was repaired four times using various techniques, including a fascia lata graft and PMMC flap. However, TEF still recurred after these four operations. The final surgical strategy involved an esophageal transection as a palliative therapy, which improved the respiratory condition, followed by closure of the TEF and subtotal esophageal resection. Finally, esophageal reconstruction using a gastric tube after the complete remission of inflammation was effective. This multi-stage surgery was considered the only choice to rescue the patient and effectively prevent another recurrence.

DOI： 10.3389/fped.2022.1053154

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

Hernioplasty for giant inguinal hernias can cause abdominal compartment syndrome (ACS) in adults but rarely does in infants. We encountered a case of a giant bilateral inguinal hernia in infancy complicated by ACS after hernioplasty. Silo placement via a skin incision effectively treated ACS, after which the abdominal wall was safely closed. Hernioplasty performed early in the clinical course can help expand the abdominal cavity and avoid ACS. Thus, hernioplasty should be performed earlier if the hernia size in the flank space gradually increases.

DOI： 10.3389/fped.2022.1030934

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: The prognosis of BA is known to be poor if definitive surgery is performed too late. Therefore, excluding BA as a diagnosis at an early stage is crucial. Conventional cholangiography requiring cannulation through the gallbladder may be unnecessarily invasive for patients, especially when ruling out BA. Therefore, a less invasive alternative such as indocyanine green (ICG) cholangiography, which does not require cannulation, should be established. In this study, we focused on excluding BA and confirmed the usefulness of intravenous ICG fluorescence cholangiography. To the best of our knowledge, this is the first preliminary study to report the use of intravenous ICG cholangiography for BA exclusion. METHODS: The study participants were patients who underwent liver biopsy and intraoperative cholangiography after they were suspected to have BA, between 2013 and 2022. ICG fluorescence cholangiography was performed on all patients who provided informed consent. RESULTS: During the study period, 88 patients underwent a laparoscopic liver biopsy and cholangiography. Among them, 65 (74%) were diagnosed with BA and underwent a subsequent laparoscopic Kasai portoenterostomy. BA was ruled out intraoperatively in 23 patients. Of the 23 patients in whom BA was ruled out, 14 underwent ICG cholangiography, 11 had gallbladder (GB) fluorescence, and 9 had both GB and common bile duct (CBD) fluorescence. Conventional cholangiography was very difficult in 2 of 23 cases: in 1 case, cannulation of the atrophic gallbladder was impossible, and cholecystectomy was indicated after multiple attempts; in 1 case, upstream cholangiography was not possible. In both cases, ICG fluorescence cholangiography successfully imaged the CBD and the GB. CONCLUSIONS: In conclusion, intravenous ICG fluorescence cholangiography might be a useful and less invasive diagnostic procedure that can rule out BA in infants.

DOI： 10.3389/fped.2022.1005879

PubMed

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.3389/fped.2022.1090336

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.45.0_77

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.45.0_74

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2022081278

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.83.4.765

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：Surgical Endoscopy  

Background: Most studies reporting the outcomes of laparoscopic ovarian prolapsed hernia operations with large sample sizes are based on intracorporeal closure, while studies on extraperitoneal closure have limited sample sizes. We proactively used the single-incision laparoscopic percutaneous extraperitoneal closure (SILPEC) technique and obtained favorable outcomes, which we report in this paper. Methods: We retrospectively reviewed patients who had undergone laparoscopic surgery for inguinal hernia at our institution. They were retrospectively classified into two groups based on the pre- or intraoperative diagnosis of hernia with a prolapsed ovary, namely the prolapse group and the non-prolapse group, respectively. The data were statistically analyzed and p < 0.05 was considered statistically significant. Results: A total of 771 subjects underwent SILPEC during the study period, including 400 girls. Among them, 63 girls were diagnosed with an ovarian prolapsed hernia. SILPEC was successfully performed through a single port in all cases, with a single exception, in whom the forceps was inserted directly through the right lower quadrant to pull up the ovary. The duration of surgery in the prolapse group was not higher than that in the non-prolapse group. During the SILPEC surgery, the ovaries were successfully reverted into the abdominal cavity by external compression of the inguinal area alone in 38 of the 63 patients. In the remaining 25 cases, the ovaries were reverted into the abdominal cavity by external compression of the inguinal area and traction of the round ligament with forceps. None of these cases failed to return to the ovaries. Conclusion: Our study results indicate that SILPEC may be performed safely for the treatment of ovarian prolapsed inguinal hernia. Since the ovary and fallopian tube are close to the internal inguinal ring due to the short round ligament, the procedure requires careful suturing with traction of the round ligament.

DOI： 10.1007/s00464-021-08777-4

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatrics International  

Background: Endoscopic variceal ligation (EVL) is a widely accepted treatment for esophagogastric varices in patients with portal hypertension (PHT). It is used for urgent treatment and prophylactic treatment of esophagogastric varices in pediatric as well as adult patients. However, major life-threatening adverse events such as early rebleeding can occur. Although early rebleeding after EVL among children and adolescents has been reported, the risk factors remain obscure. This study evaluated the risk factors for early rebleeding after EVL in children and adolescents. Methods: The subjects were children and adolescents (<18 years) with PHT who underwent EVL for esophagogastric varices. Early rebleeding was defined as hematemesis, active bleeding, or blood retention in the stomach, confirmed by esophagogastroduodenoscopy from 2 h to 5 days after EVL. Results: A total of 50 EVL sessions on 22 patients were eligible for this study. There were four episodes of early rebleeding. No other major adverse event has occurred. Multivariate analysis showed that EVL implemented at cardiac varices just below the esophagogastric junction (EGJ), within 5 mm from the EGJ, is the independent factor for a higher risk of early rebleeding: odds ratio 18.2 (95% confidence interval: 1.40–237.0), P = 0.02. Conclusions: Children and adolescents who undergo EVL for cardiac varices just below the EGJ have a higher risk of early rebleeding than those who do not.

DOI： 10.1111/ped.14614

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Surgery Today  

Purpose: To investigate late complications after surgery for congenital biliary dilatation (CBD). Methods: We retrospectively reviewed the patients treated for late postoperative complications of extrahepatic bile duct resection with bilioenteric anastomosis for CBD at our hospital between 1999 and 2019. Results: Twenty-seven complications, including bile duct stenosis with (n = 19) or without (n = 3) hepatolithiasis, remnant intrapancreatic bile duct (n = 2), intestinal obstruction (n = 2), and refractory cholangitis (n = 1) were treated in 26 patients. The median age at radical surgery and the initial treatment of complications was 3 years, 2 months and 14 years, 5 months, respectively. The median period from radical surgery to initial treatment of complications was 7 years, 1 month. Before 2013, bile duct stenosis was initially treated with bile duct plasty (n = 11) or hepatectomy (n = 3), and 71.4% (n = 10) of patients needed further treatment; after 2013, double-balloon endoscopic retrograde cholangiography (DBERC) was used (n = 8), and 25% (n = 2) of patients needed further treatment. Patients with remnant intrapancreatic bile duct, intestinal obstruction, and refractory cholangitis required surgery. Conclusion: Long-term follow-up is necessary after surgery for congenital biliary dilatation. DBERC is thus considered to be useful for bile duct stenosis management.

DOI： 10.1007/s00595-021-02238-0

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

Purpose: Tracheomalacia (TM) is a frequent complication after esophageal atresia (EA) repair. This study aimed to review patients who underwent aortopexy for TM after EA repair and to compare their imaging features. Methods: The patients who underwent thoracoscopic EA repair and contrast-enhanced computed tomography (CECT) at our hospital between 2013 and 2020 were retrospectively reviewed. The ratio of the lateral and anterior–posterior diameter of the trachea (LAR) where the brachiocephalic artery (BCA) crosses the trachea was defined. The LAR of the patients who underwent CECT for asymptomatic pulmonary disease was set as a normal reference. The Z-score of each LAR was calculated and compared between the patients that did or did not undergo aortopexy. Results: A total of 51 patients represented the controls, 5 patients underwent aortopexy, and 12 patients were discharged without surgery. The mean LARs in the patients who underwent aortopexy, did not undergo aortopexy, and controls were 3.54, 1.54, and 1.15, respectively. The mean Z-score of the aortopexy group was 21.2. After successful aortopexy, each patient’s LAR decreased to < 1.5. Conclusion: Aortopexy was preferred if the trachea was compressed by the BCA. The LAR is a useful indicator for predicting the therapeutic effect of aortopexy.

DOI： 10.1007/s00383-021-04985-0

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

Purpose: Minimally invasive examinations are particularly important in pediatric patients. Although the significance of urinary N1,N12-diacetylspermine (DiAcSpm) as a tumor marker (TM) has been reported in many types of adult cancers, its usefulness in pediatric cancers has not been reported. This may be due to urinary DiAcSpm level variations with age. This study aims to measure the normal levels of urinary DiAcSpm in healthy individuals and investigate its usefulness as a TM in childhood cancer. Methods: Urinary samples were collected from pediatric patients with and without cancer. The urinary DiAcSpm levels were measured, and the values were compared. Results: A total of 32 patients with cancer and 405 controls were enrolled in the study. Of the 32 patients, 13 had neuroblastoma, 9 had malignant lymphoma (ML), and 10 had leukemia. In the control group, the urinary DiAcSpm values markedly fluctuated among those with young age, especially infants; meanwhile, the values converged among those aged roughly 10 years and above. The sensitivity of DiAcSpm was significantly different among the three types of cancers: neuroblastoma (30.8%), ML (77.8%), and leukemia (40%). Conclusion: The urinary DiAcSpm value is a useful TM for both screening and follow-up of ML.

DOI： 10.1007/s00383-021-04987-y

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

Purpose: The effectiveness of laparoscopic Kasai portoenterostomy (Laparoscopic-KPE) for biliary atresia (BA) has been reported but remains controversial. We reviewed our own cases and cases described in previous studies of liver transplantation (LT) for BA after Laparoscopic-KPE to investigate the efficacy of Laparoscopic-KPE. Methods: Subjects were children of ≤ 2 years old with LT for BA after KPE who underwent Laparoscopic-KPE (n = 10) or Open-KPE (n = 115) between 2009 and 2020. Propensity score matching was performed to reduce the effect of treatment selection bias. The clinical data regarding the preoperative characteristics and surgical results were compared. Results: The rates of hypoplastic portal vein and retrograde portal vein flow were lower in the Laparoscopic-KPE group than in the Open-KPE group (0 vs. 40.0%, p = 0.02 and 0 vs. 35.0%, p = 0.04). There was no marked difference in the operation time or duration of hepatectomy. For portal vein reconstruction, a vein graft was not required in the Laparoscopic-KPE group (0 vs. 35.0%, p = 0.03). No patients in the Laparoscopic-KPE group developed portal vein complications or required re-laparotomy for bowel perforation or re-bleeding, in contrast to the Open-KPE group (0 vs. 15.0% and 0 vs. 10.0%, respectively). Conclusion: Laparoscopic-KPE may reduce postoperative complications that necessitate re-laparotomy in LT.

DOI： 10.1007/s00383-021-04994-z

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

Background: Minimally invasive surgery (MIS) is appropriate for the treatment of some neuroblastomas (NBs); however, the indications and technical issues are unclear. This study aimed to clarify the current status of MIS for mediastinal NB in Japan. Methods: Preliminary questionnaires requesting the numbers of neuroblastoma cases in which MIS was performed from 2004 to 2016 were sent to 159 Japanese institutes of pediatric surgery. Secondary questionnaires were sent to institutions with MIS cases to collect detailed data. Results: One hundred thirty-four (84.2%) institutions returned the preliminary questionnaire and 83 institutions (52.2%) reported a total of 1496 operative cases. MIS was performed for 175 (11.6%) cases. Among the 175 cases, completed forms of 140 patients were returned and 40 (male, n = 28; female, n = 12) cases had mediastinal NB. Fourteen patients received thoracoscopic biopsy, none were converted to thoracotomy. Twenty-eight patients received MIS for radical resection, none were converted to thoracotomy. Perioperative complications (Horner’s syndrome) were recognized after radical resection in one (2.5%) case. Conclusions: MIS was performed in a limited number of mediastinal NB cases. A thoracoscopic approach would be feasible for mediastinal NB.

DOI： 10.1007/s00383-021-04998-9

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

Purpose: The features of right-sided congenital diaphragmatic hernias (RCDHs) are quite different from those of left-sided CDHs (LCDHs). We have summarized the features of RCDHs experienced in our institution. Methods: This retrospective study analyzed the cases of patients with CDH registered at our institution between 2011 and 2020. Defects on each side were compared based on prenatal diagnosis, medical treatment, type of surgery, and outcomes. Results: A total of 101 patients underwent surgery at our institution during the neonatal period, and 11 had RCDHs. RCDHs and LCDHs were significantly different in terms of extracorporeal membrane oxygenation (36% vs. 6%, p = 0.002), patch repair (81% vs. 28%, p < 0.001), recurrence rate (36% vs. 11%, p = 0.022), and length of hospital stay (117 days vs. 51 days, p = 0.012). The severity of the fetal diagnosis did not reflect postnatal severity. All patients with RCDH survived to discharge, and there was no significant difference in survival rate between the right and left sides. Conclusion: Neonates with RCDH required more intensive treatments; however, the survival rate was comparable between RCDH and LCDH. RCDH was significantly different from LCDH and an optimal treatment strategy for RCDHs should be established.

DOI： 10.1007/s00383-021-04999-8

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Nagoya Journal of Medical Science  

A 45-year-old female was admitted to the hospital with a diagnosis of acute pancreatitis. A computed tomography scan showed two extrahepatic bile ducts. Magnetic resonance cholangiopancreatography suggested a stone in one of the bile ducts. Endoscopic retrograde cholangiopancreatography revealed two extrahepatic bile ducts joining at the hilum of the liver accompanied with pancreaticobiliary maljunction. Sphincterotomy was performed and a protein plug was drained from the bile duct. Several treatment options were discussed, and the patient was treated with laparoscopic cholecystectomy without extrahepatic bile duct resection and planned to be followed up considering the risk of carcinogenesis in the bile ducts.

DOI： 10.18999/nagjms.83.3.655

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Familial Cancer  

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is caused by heterozygous germline variants in the fumarate hydratase (FH) gene and is associated with increased susceptibility to cutaneous leiomyomas, uterine leiomyomas, and renal cell carcinoma (RCC). HLRCC-associated RCC usually occurs in the middle age, with the median age being 40–44 years. This report describes a seven-year-old (84-month-old) male who developed a large right kidney tumor with multiple cystic lesions that contained enhanced solid components. There was no evidence of distant metastasis. The male patient underwent right nephrectomy and has been recovering well without metastasis or recurrence. Pathological examination revealed that tumor cells with relatively prominent nucleoli and surrounded by halos, were located in a limited area. Immunohistochemical staining was negative for FH. Whole-exome sequencing identified his germline variant in the FH gene and its loss of heterozygosity in the tumor. At nine years (114 months) of age, the male patient showed no recurrence of the tumor. This was the youngest-onset case of HLRCC-associated RCC to date. This report may affect the starting age for future RCC-surveillance programs for patients with HLRCC.

DOI： 10.1007/s10689-021-00268-8

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Surgical Endoscopy  

Background: Some neuroblastoma (NB) cases are suitable for minimally invasive surgery (MIS), but indication and technical issue are unclear. We assessed the current status of MIS for abdominal NB after mass screening period in Japan. Methods: Preliminary questionnaires requesting the numbers of NB cases that underwent MIS from 2004 to 2016 were sent to 159 Japanese institutes of pediatric surgery. The secondary questionnaires were then sent to the institutions that reported MIS cases of NB in order to collect detailed data. Results: One hundred and thirty-four (84.2%) institutions responded to the preliminary questionnaires, and 83 (52.2%) reported managing operative cases. The total number of operative cases was 1496. MIS was performed for 175 (11.6%) cases, of which the completed forms of 140 patients were returned, including 100 abdominal NB cases. The male/female ratio was 51/49. Forty-seven cases underwent a laparoscopic biopsy, and 2 (4.3%) cases were converted to laparotomy due to bleeding. Sixty-five cases underwent MIS for radical resection, and 7 (10.8%) were converted to laparotomy. The reasons for open conversion were bleeding and severe adhesion. Regarding open conversion, there were no significant relationships between conversion and neo-adjuvant chemotherapy, biopsies, stage, size, or MYCN amplification. We found no relationship between resectability and vascular encasement in this study. There was relationship between the resected tumor size and the patients’ height, which was expressed using the following formula: y= 0.0316 x+ 1.4812 (x, patients height, y, tumor size; p = 0.004219, SE: 1.55566). Postoperative complications after radical resection were recognized in 7 (10.8%) cases. Conclusions: MIS was performed in limited cases of abdominal NB. A laparoscopic biopsy with careful attention to bleeding is feasible. The resected tumor size was shown to correlate with the patients’ height. Tumor size within 6 cm of maximum diameter can be resected safely.

DOI： 10.1007/s00464-021-08599-4

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Pediatric Surgery International  

A correction to this paper has been published: https://doi.org/10.1007/s00383-021-04873-7.

DOI： 10.1007/s00383-021-04873-7

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Scientific Reports  

Bile duct and anastomotic strictures and intrahepatic stones are common postoperative complications of congenital biliary dilatation (CBD). We performed double-balloon endoscopic retrograde cholangiography (DBERC) for diagnostic and therapeutic purposes after radical surgery. We focused on the effectiveness of DBERC for the treatment of postoperative complications of CBD patients. Bile duct and anastomotic strictures and intrahepatic stones are common postoperative complications of congenital biliary dilatation (CBD). We performed double-balloon endoscopic retrograde cholangiography (DBERC) for diagnostic and therapeutic purposes after radical surgery. We focused on the effectiveness of DBERC for the treatment of postoperative complications of CBD patients. This retrospective study included 28 patients who underwent DBERC (44 procedures) after radical surgery for CBD between January 2011 and December 2019. Strictures were diagnosed as “bile duct strictures” if endoscopy confirmed the presence of bile duct mucosa between the stenotic and anastomotic regions, and as “anastomotic strictures” if the mucosa was absent. The median patient age was 4 (range 0–67) years at the time of primary surgery for CBD and 27.5 (range 8–76) years at the time of DBERC. All anastomotic strictures could be treated with only by 1–2 courses of balloon dilatation of DBERC, while many bile duct strictures (41.2%) needed ≥ 3 treatments, especially those who underwent operative bile duct plasty as the first treatment (83.3%). Although the study was limited by the short follow-up period after DBERC treatment, DBERC is recommended as the first-line treatment for hepatolithiasis associated with biliary and anastomotic strictures in CBD patients, and it can be safely performed multiple times.

DOI： 10.1038/s41598-021-90550-7

Web of Science

Scopus

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2021229976

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1200/JCO.2021.39.15_suppl.e22008

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p><i>Purpose</i>: The treatment outcomes of patients with laparoscopic surgery for biliary atresia (laparoscopic portoenterostomy) were retrospectively evaluated to determine whether to limit the laparoscopic surgery for biliary atresia to fully experienced surgeons.</p><p><i>Methods</i>: We included 37 patients with laparoscopic portoenterostomy for biliary atresia at our institution from 2014 to 2018. Twelve patients were treated by a surgeon fully experienced in laparoscopic portoenterostomy (Group A) and 23 patients were treated by other surgeons (Group B). Jaundice reduction and jaundice-free survival of patients with the native liver in the two groups were compared.</p><p><i>Results</i>: Differences in age at the time of surgery, body weight, perioperative blood loss, time of drain removal, and time that milk or formula feeding resumed in both groups were not significant. The duration of surgery was significantly shorter in Group A than in Group B. The jaundice-free survival rates of patients with the native liver were 58.3% in Group A and 60.9% in Group B at 6 months after surgery, 66.7% in Group A and 65.2% in Group B at 1 year after surgery, and 58.3% in Group A and 56.5% in Group B at 2 years after surgery. No significant difference was observed.</p><p><i>Conclusions</i>: In this study, no significant difference in the rate of jaundice-free survival of patients with the native liver depending on the amount of surgical experience was observed under the guidance of an operator who was skilled in laparoscopic portoenterostomy.</p>

DOI： 10.11164/jjsps.57.3_596

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Scientific Reports  

Diagnosis of biliary atresia (BA) can involve uncertainties. In the present prospective multicenter study, we considered whether urinary oxysterols represent a useful marker for diagnosis of BA in Japanese children. Subjects under 6 months old at 7 pediatric centers in Japan were prospectively enrolled, including patients with cholestasis and healthy controls (HC) without liver disease. Patients with cholestasis constituted 2 groups representing BA patients and others with cholestasis from other causes (non-BA). We quantitatively analyzed 7 oxysterols including 4β-, 20(S)-, 22(S)-, 22(R)-, 24(S)-, 25-, and 27-hydroxycholesterol by liquid chromatography/electrospray ionization-tandem mass spectrometry. Enrolled subjects included 14 with BA (median age 68 days; range 26–170) and 10 non-BA cholestatic controls (59; 14–162), as well as 10 HC (57; 25–120). Total urinary oxysterols were significantly greater in BA (median, 153.0 μmol/mol creatinine; range 24.1–486.7; P < 0.001) and non-BA (36.2; 5.8–411.3; P < 0.05) than in HC (2.7; 0.8–7.6). In patients with BA, urinary 27-hydroxycholesterol (3.61; 0.42–11.09; P < 0.01) was significantly greater than in non-BA (0.71; 0–5.62). In receiver operating characteristic (ROC) curve analysis for distinguishing BA from non-BA, the area under the ROC curve for urinary 27-hydroxycholesterol was 0.83. In conclusion, this first report of urinary oxysterol analysis in patients with BA indicated that 27-hydroxycholesterol may be a useful marker for distinguishing BA from other causes of neonatal cholestasis.

DOI： 10.1038/s41598-021-84445-w

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Scientific Reports  

Urine is a complex liquid containing numerous small molecular metabolites. The ability to non-invasively test for cancer biomarkers in urine is especially beneficial for screening child patients. This study attempted to identify neuroblastoma biomarkers by comprehensively analysing urinary metabolite samples from children. A total of 87 urine samples were collected from 54 participants (15 children with neuroblastoma and 39 without cancer) and used to perform a comprehensive analysis. Urine metabolites were extracted using liquid chromatography/mass spectrometry and analysed by Metabolon, Inc. Biomarker candidates were extracted using the Wilcoxon rank sum test, random forest method (RF), and orthogonal partial least squares discriminant analysis (OPLS-DA). RF identified three important metabolic pathways in 15 samples from children with neuroblastoma. One metabolite was selected from each of the three identified pathways and combined to create a biomarker candidate (3-MTS, CTN, and COR) that represented each of the three pathways; using this candidate, all 15 cases were accurately distinguishable from the control group. Two cases in which known biomarkers were negative tested positive using this new biomarker. Furthermore, the predictive value did not decrease in cases with a low therapeutic effect. This approach could be effectively applied to identify biomarkers for other cancer types.

DOI： 10.1038/s41598-021-83619-w

Web of Science

Scopus

PubMed

Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-020-04791-0

Web of Science

Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-020-04793-y

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Nagoya Journal of Medical Science  

Early detection of diseases is critical in infants. This study evaluates the usefulness of web searches in predicting diseases in order to encourage guardians to consult a doctor promptly if their children are ill. We collected six months of search queries from Yahoo! JAPAN Search between October 2016 and March 2017. Using a machine learning model, we investigated the accuracy of the search query’s ability to predict the diagnosis of biliary atresia and hypertrophic pyloric stenosis. Both diseases were modeled with an accuracy of approximately 80&, and symptoms related to the disease were significant features in the model. These findings suggest the possibility of detecting diseases from web search queries performed by guardians. Through future research, we intend to propose a method that uses web search queries for early detection of these diseases by providing appropriate and timely information to support the guardians of patients.

DOI： 10.18999/nagjms.83.1.107

Web of Science

Scopus

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p>The patient was a newborn female with colonic atresia and gastroschisis. A silo was placed immediately after birth and surgery was scheduled the following day. Adhesive detachment was performed by washing the intestinal tract with saline. The oral and anal segments of the colonic atresia were identified, and functional end-to-end anastomosis was performed. Severe edema precluded the immediate return of the intestines to the abdominal cavity and required ongoing treatment with a silo. The intestines gradually returned to the abdominal cavity during the following week. The abdominal wall was closed on postnatal day 9 by a sutureless method. The patient's postoperative course was good, and full feeding was initiated on postnatal day 19. The patient was discharged from the hospital on postnatal day 32 and recovered without complications. In cases of gastroschisis with colonic atresia, a two-stage surgical procedure is commonly employed. However, functional end-to-end anastomosis using a linear stapler is also an effective method because anastomoses can be performed without regard to differences in intestinal caliber.</p>

DOI： 10.11164/jjsps.57.1_22

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p>A 21-month-old girl with chief complaints of vomiting and fever was admitted to a hospital and diagnosed as having congenital biliary dilatation. Magnetic resonance imaging performed on the sixth day of hospitalization revealed bile duct perforation, and the patient was transferred to our department for further treatment. A perforation approximately 2 cm in diameter was found at the confluence of the common bile duct and cystic duct. We concluded that biliary drainage and repair of the perforation would not improve her pathophysiology. Therefore, laparoscopic one-stage radical surgery was performed. In addition, bile duct plasty was performed to treat the severe intrahepatic bile duct membranous stenosis that were observed in the right and left bile ducts of the hepatic hilum. The patient was discharged without complications on the tenth postoperative day.</p><p>Two-stage surgery is the recommended treatment method for congenital biliary dilatation with biliary perforation. However, in recent years, there have been few reports showing that one-stage open radical surgery is useful. In this case, we successfully performed laparoscopic one-stage radical surgery for congenital biliary dilatation with biliary perforation. If laparoscopic radical surgery for congenital biliary dilatation is established at the institution, and the patient is in good general condition, laparoscopic one-stage radical surgery may be an effective modality for treating this condition.</p>

DOI： 10.11164/jjsps.57.5_855

Language：English   Publishing type：Research paper (international conference proceedings)   Publisher：SPIE  

DOI： 10.1117/12.2581261

Web of Science

Scopus

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.44.0_50

CiNii Research

Language：English   Publishing type：Research paper (international conference proceedings)   Publisher：Springer  

DOI： 10.1007/978-3-030-90874-4_1

Other Link： https://dblp.uni-trier.de/db/conf/clip-ws/clip2019.html#OdaHKTHUSOM21

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.44.0_72

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2021085587

CiNii Research

Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12893-020-00986-3

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)  

Web of Science

Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12887-020-02183-w

Web of Science

Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s10147-020-01620-1

Web of Science

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2020230886

CiNii Research

Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.compbiomed.2019.103471

Web of Science

Publishing type：Research paper (scientific journal)  

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.43.0_84

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

DOI： 10.34410/jspbm.43.0_36

Language：English   Publishing type：Research paper (international conference proceedings)   Publisher：SPIE-INT SOC OPTICAL ENGINEERING  

This paper presents a visualization method of intestine (the small and large intestines) regions and their stenosed parts caused by ileus from CT volumes. Since it is difficult for non-expert clinicians to find stenosed parts, the intestine and its stenosed parts should be visualized intuitively. Furthermore, the intestine regions of ileus cases are quite hard to be segmented. The proposed method segments intestine regions by 3D FCN (3D U-Net). Intestine regions are quite difficult to be segmented in ileus cases since the inside the intestine is filled with fluids. These fluids have similar intensities with intestinal wall on 3D CT volumes. We segment the intestine regions by using 3D U-Net trained by a weak annotation approach. Weak-annotation makes possible to train the 3D U-Net with small manually-traced label images of the intestine. This avoids us to prepare many annotation labels of the intestine that has long and winding shape. Each intestine segment is volume-rendered and colored based on the distance from its endpoint in volume rendering. Stenosed parts (disjoint points of an intestine segment) can be easily identified on such visualization. In the experiments, we showed that stenosed parts were intuitively visualized as endpoints of segmented regions, which are colored by red or blue.

DOI： 10.1117/12.2548910

Web of Science

Scopus

Other Link： https://dblp.uni-trier.de/db/journals/corr/corr2003.html#abs-2003-01290

Publishing type：Research paper (scientific journal)  

Web of Science

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2020041175

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1038/s41598-019-51123-x

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-019-04541-x

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-019-04537-7

Web of Science

PubMed

Publishing type：Research paper (scientific journal)  

Web of Science

Language：English   Publishing type：Research paper (other academic)   Publisher：Springer  

DOI： 10.1007/978-3-030-32689-0_11

Other Link： https://dblp.uni-trier.de/db/conf/miccai/clip2019.html#OdaNKVACHUSIOM19

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00464-019-07108-y

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/hepr.13381

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

DOI： 10.24479/j00645.2019185000

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1038/s41598-019-42027-x

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/jhbp.594

Web of Science

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：一般社団法人エレクトロニクス実装学会  

<p>心電図モニタリング用のドライ電極の開発を行った。ドライ電極を用いた心電図モニタリングにおいての課題は皮膚-電極間の安定した接触である。我々は立体構造の樹脂に銀メッキ加工を施した繊維を静電植毛することにより、体の形状に沿った形状であり、皮膚-電極間の安定した接触を実現した、ドライ電極の作製を行った。また作製したドライ電極を用いて心電図モニタリングウェアを作製し、医療的意義のある心電図測定に成功した。</p>

DOI： 10.11486/ejisso.33.0_13a2-01

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：公益社団法人 日本生体医工学会  

<p>腹腔鏡手術は低侵襲性であることから普及が進んでいる。しかしながら、カメラを通じた状況把握、ポート留置部を支点とするため移動方向が手の動きと逆になる腹腔鏡用鉗子の利用など、手術の難易度が高く、習得に時間がかかることことから熟練者不足が問題となっている。また熟練医の不足は修練者のための教育に当てる時間も不足するという悪循環を生んでいる。従って、熟練者を短期間で養成し増やすための術式教育そのものが重要な課題である。本研究では、内視鏡外科手術は術野像がモニタによって同じ視野が「共有される」という特性を利用して、段階的な学習ステップに応じた、熟練者の適切かつスムースな動きを修練者が追体験することで、非言語的なスキルの伝達を行い、効果的なトレーニングを行うシステムである「追いトレ」を用いた場合の効果について、妥当性、効果の範囲、適応可能な範囲を明らかし、製品化・実用化・普及を実現するエビデンスを獲得するために、様々な内視鏡外科分野で十分な検証実験を踏まえたデータ取得とデータ解析を行なうことを目的とした。</p>

DOI： 10.11239/jsmbe.Annual57.S198_1

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.bjps.2018.12.027

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.crad.2018.08.008

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.80.4.497

Web of Science

Scopus

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00595-018-1636-9

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2018.0330

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-018-4318-1

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-018-4313-6

Web of Science

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

PURPOSE: Laparoscopic-assisted anorectoplasty (LAARP) is a minimally invasive procedure in which the levator ani muscle is left to potentially improve postoperative fecal continence. This study aimed to retrospectively evaluate postoperative complications and long-term outcomes of fecal continence after LAARP and compare them to those after posterior sagittal anorectoplasty (PSARP). METHODS: Forty-five male patients with high and intermediate anorectal malformation (aged ≥ 4 years) who underwent LAARP or PSARP (LAARP 29, PSARP 16) from 1999 to 2013 were included. Postoperative complications and postoperative fecal continence were retrospectively evaluated and compared. Postoperative complications were also compared before and after introducing a urethroscope during fistula resection. RESULTS: Complications after LAARP and PSARP were seen in 12 vs. 2 cases (p = 0.09) of mucosal prolapse and in 9 vs. 1 case (p = 0.07) of posterior urethral diverticulum (PUD), respectively. The incidence of PUD decreased after introduction of a urethroscopy from 40% in 8/20 cases to 11% in 1/9 cases. No significant difference was found in terms of fecal continence in both groups. CONCLUSION: Through our study, greater improvement of postoperative fecal continence after LAARP has not been shown. LAARP was at higher risk for mucosal prolapse and PUD. However, precise dissection of the urethral fistula could be performed after the introduction of urethroscopy.

DOI： 10.1007/s00383-018-4323-4

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PURPOSE: Anovestibular fistula (AVF) is the most common type of anorectal malformation in females. Delayed anorectoplasty with fistula dilatation is commonly performed during infancy; however, we have been actively performing anorectoplasty in neonates. We report the surgical complications and postoperative defecation function associated with single-stage anorectoplasty performed in neonates. METHODS: Patients who underwent surgery for AVF between 2007 and 2017 at two institutions were retrospectively studied. The operation time, amount of bleeding, time to start oral intake, perioperative complications, and Kelly's score were compared among patients who underwent surgery as neonates and those who underwent surgery as infants. RESULTS: Eighteen neonates and 17 infants underwent anterior sagittal anorectoplasty. The median operation time and time to start oral intake were significantly shorter in the neonatal group (72 min; 3 days, respectively) than in the infant group (110 min, p = 0.0002; 5 days, p = 0.0024, respectively). Postoperative wound disruption was significantly more frequent in the infant group. Of the ten patients each in the neonatal and infant groups, there was no significant difference in Kelly's score at age ≥ 4 years. CONCLUSION: Single-stage anorectoplasty in neonates with AVF can be feasibly performed and does not impair postoperative defecation function. LEVELS OF EVIDENCE: III.

DOI： 10.1007/s00383-018-4324-3

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-018-4320-7

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2018.04.030

Web of Science

PubMed

Language：English   Publishing type：Research paper (other academic)  

Language：English   Publishing type：Research paper (other academic)  

Language：English   Publishing type：Research paper (international conference proceedings)   Publisher：Institute of Electrical and Electronics Engineers Inc.  

We developed textile-based multi-lead ECG measurement wear. The textile-based ECG measurement wear was fabricated by printed electronics and electrostatic flocking technology. We also developed a wireless communication system of multi-lead ECG signals. Moreover, we succeeded to get 18-lead ECG signals around heart using the ECG measurement wear and the wireless measuring system.

DOI： 10.23919/ICEP.2018.8374690

Scopus

Language：Japanese   Publishing type：Research paper (scientific journal)  

BACKGROUND: Postoperative chylothorax after surgery for esophageal atresia/tracheoesophageal fistula (TEF) is a rare but serious complication, especially in neonates. This study aimed to identify the thoracic duct and ligate chylous leakage sites, using thoracoscopic navigation of an indocyanine-green (ICG)-based near-infrared (NIR) fluorescence imaging system. METHODS: From November 2014 to April 2017, thoracoscopic intraoperative ICG-NIR imaging was performed in 10 newborns (11 surgeries) with first TEF operation or with persistent postoperative chylothorax after TEF operation. NIR imaging was performed 1h after an inter-toe injection of ICG. Thoracoscopic ligations against the NIR-detected leakage sites were performed with sutures. RESULTS: The thoracic duct or lymphatic leakage was directly visualized in each patient. In 8 surgeries with first thoracoscopic TEF operation, one case had suspected minor chylous leakage without postoperative chylothorax. Another case with no chylous leakage at the first operation resulted in chylothorax at postoperative day 11. In three neonates with postoperative chylothorax, leakage points were detected near the ablation site of the azygos vein during the first operation. These points were properly ligated, and postoperative chylous leakage ceased with no adverse events. CONCLUSIONS: Thoracoscopic ICG-NIR imaging encourages the repair of refractory chylothorax and seems reliable. LEVEL OF EVIDENCE: IV.

DOI： 10.1016/j.jpedsurg.2018.01.019

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：金原出版  

DOI： 10.18888/op.0000000707

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpeds.2017.12.058

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2017.0307

Web of Science

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12887-018-1085-z

Web of Science

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japan Institute of Electronics Packaging  

DOI： 10.11486/ejisso.32.0_179

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p>The patient was a 5-year-old boy who had no medical history. He was referred to us with suspected acute appendicitis and complaints of fever and lower abdominal pain. Although his abdominal pain was intense, rebound tenderness and muscular protection were negative. There were no symptoms of problems in the digestive tract such as vomiting or diarrhea. His blood examination revealed an increase in inflammatory reactions, as indicated by the increased white blood cell count and C-reactive protein levels. Computed tomography (CT) revealed wall thickening of the ascending colon; therefore, we started antibiotic administration after acute enterocolitis was diagnosed. After admission, we performed CT again and found a fatty and dense mass with a swirling structure inside the mass; therefore, we diagnosed the patient as having idiopathic omental torsion. Because the symptoms were relieved, conservative management was continued and the patient was discharged on the fourth day after hospitalization. Omental torsion is a rare condition, particularly seen in children; its classical treatment option is surgery. Although conservative management was successful in this case, there are few reports on it. There are many cases where surgery is performed after an initial diagnosis of acute appendicitis is made owing to the presence of similar symptoms. However, in recent years, because of advances in imaging diagnostic techniques such as CT, more patients are being accurately diagnosed. We believe that if patients are accurately diagnosed, surgery will always be required; however, conservative management is sometimes possible.</p>

DOI： 10.11164/jjsps.54.2_302

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/978-3-030-00934-2_26

Web of Science

Scopus

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2017.08.056

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12893-017-0313-z

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2017.10.061

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.79.4.427

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-017-4140-1

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1080/08941939.2017.1366603

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.79.3.415

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00464-017-5472-6

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.12659/AJCR.903465

Web of Science

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1186/s12887-017-0826-8

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2016.0207

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p>Reports on laparoscopic hepatectomy for malignant tumors in children are few. We present a case of pure laparoscopic partial hepatectomy for hepatoblastoma. A baby girl with Beckwith-Wiedemann syndrome underwent surgical closure of an omphalocele on the sixth day of life. At 4 months, sonographic screening revealed a liver tumor. The alpha-fetoprotein level was 23,060.69 ng/ml, and contrast-enhanced computed tomography revealed a 3.7-cm mass at the left lateral segment of the liver. A biopsy of the mass confirmed the diagnosis of hepatoblastoma (PRETEXT I). After 4 cycles of cisplatin monotherapy, the size of the tumor decreased to 2.7 cm. Laparoscopic partial hepatectomy was performed when she was 6 months old. An umbilical incision was made in an inverted Y shape, allowing for E-Z Access^TM with a Lap Protector^TM insertion through which a 1.2-cm trocar was introduced. Two 5-mm working ports were placed lateral to the rectus muscle of either side immediately superior to the umbilicus. After placing a tape around the porta hepatis for the Pringle maneuver in the case of severe bleeding, intraoperative ultrasonography was performed for the identification of the vascular tree and hepatic and portal veins, and the localization of the tumor for accurate and safe resection. Enseal^® was used to divide the hepatic parenchyma. Branched vessels and ducts were clipped and transected using Enseal^®. The surgical specimen was extracted through the umbilical incision without enlarging the incision. The patient had an uncomplicated recovery. No recurrence was observed during a 2-year follow-up.</p>

DOI： 10.11164/jjsps.53.5_1073

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.18999/nagjms.78.4.447

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ped.13040

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：株式会社医学書院  

DOI： 10.11477/mf.6003200186

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00595-016-1434-1

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：WILEY  

Web of Science

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-016-3973-3

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2016.09.017

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1002/jhbp.395

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-016-3939-5

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-016-3932-z

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.4103/0972-9941.182655

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.4103/0972-9941.181771

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：NAGOYA UNIV, SCH MED  

The purpose of this study is to examine the feasibility of single-incision laparoscopic percutaneous extraperitoneal closure (LPEC) for incarcerated inguinal hernia (IIH) repair. 6 single-incision LPEC procedures were performed for IIH repair and 60 procedures were performed for reducible inguinal hernia (RIH) in the same period of time in one hospital. The laparoscope and one pair of grasping forceps were placed through the same umbilical incision. In IIH repair, the herniated organ was gently pulled using the grasping forceps with external manual pressure. If it was difficult to reduce the herniated organ with one pair of forceps, another pair of forceps were inserted through a multi-channel port without extending the umbilical incidion. Using the LPEC needle, the hernia orifice was closed extraperitoneally. We performed a retrospective analysis to compare the outcomes of single-incision LPEC for IIH repair or reducible inguinal hernia. All procedures were completed by single-incision without open conversion. A multi-channel port with another pair of forceps was needed in three cases. The operation time and the length of stay were significantly longer with IIH repair than with RIH repair. There were no major complications and there was no evidence of early recurrence in any patient. In conclusion, single-incision LPEC with a multi-channel port is feasible and safe for IIH repair.

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：Japanese   Publishing type：Research paper (scientific journal)  

Web of Science

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Elsevier Inc.  

We describe a simple and feasible procedure for single-incision laparoscopic repair of a pediatric epigastric hernia using a novel suture-assisting needle. A multichannel port was inserted through the umbilical vertical incision. After the orifice of the hernia was identified, a suture-assisting needle, which can hold a suture at its tip, with a 2-0 thread was pierced through the skin into one side of the rectus muscle sheath into the abdominal cavity. Next, after releasing the thread, the needle was pulled out to the subcutis and pierced through another side of the rectus muscle sheath. The needle, grasping the thread again, was subsequently pulled out through the abdominal wall outside, and the thread was tied extracorporeally. This knot was buried subcutaneously. Operative procedures of single-incision laparoscopic repair of an epigastric hernia have become simple and feasible with the use of a novel suture-assisting needle with an excellent cosmetic result.

DOI： 10.1016/j.epsc.2015.11.010

Web of Science

Scopus

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

<p>Fibrolamellar hepatocellular carcinoma (FLHCC) is rare in children. In Japan, there are only six reports of children with FLHCC. We report a case of FLHCC aggressively treated by surgery and chemotherapy. A 12-year-old girl with liver tumor was admitted to our hospital for treatment. FLHCC with lymph node metastases was suspected from various imaging studies and definitively diagnosed as FLHCC by laparotomy biopsy. One cycle of gemcitabine/oxaliplatin (GEMOX) chemotherapy was administered preoperatively because of multiple lymph node metastases. After chemotherapy, her PIVKA-II level decreased but there was no reduction in tumor size. As a result, left hepatectomy and lymphadenectomy were performed. GEMOX chemotherapy was administered as a postoperative adjuvant. After 2 cycles of GEMOX chemotherapy, she developed adhesive ileus and adhesiotomy was performed. Ten cycles of GEMOX chemotherapy were administered after adhesiotomy, and then she was discharged. To date, 3 years after surgery, there is no evidence of recurrence.</p>

DOI： 10.11164/jjsps.52.6_1251

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ped.12715

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Elsevier Inc.  

Patients with hepatic arteriovenous malformations rarely present with pulmonary hypertension. We report the case of a 3-month-old boy who developed severe pulmonary hypertension due to a hepatic arteriovenous malformation. The use of pulmonary vasodilators to treat the patient's pulmonary hypertension worsened his high-output heart failure. This is the first case in which emergency hepatectomy rescued a patient with hepatic arteriovenous malformations who developed pulmonary hypertension.

DOI： 10.1016/j.epsc.2015.10.017

Web of Science

Scopus

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ases.12263

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2015.0109

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ped.12599

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：NAGOYA UNIV, SCH MED  

We report a case of accessory scrotum (AS) in the perineal region with peduncular lipoma, diagnosed prenatally. A male fetus of 31 weeks' gestation was referred to our department with a perineal mass. Prenatal ultrasonography and magnetic resonance imaging showed a mass of 1.0 x 1.2 cm located posterior to the scrotum. No other abnormalities were noted during pregnancy. The patient was delivered vaginally at 38 weeks of gestation. On physical examination, a soft peduncular mass with a rugged and pigmented swelling was located between the normally developed scrotum and the anus. There were no specific symptoms or any other associated congenital anomalies. We completely excised the mass at one month of age. A histological examination revealed lipoma, with tissue suggestive of scrotum, so a definite diagnosis of AS was made. AS is a rare congenital anomaly of the scrotum. We review the literature.

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：English   Publishing type：Research paper (scientific journal)   Publisher：NAGOYA UNIV, SCH MED  

Femoral hernias are relatively rare in children, and more than half of pediatric femoral hernias are misdiagnosed. A 3-year-old boy was treated for an indirect inguinal hernia at the age of 2, but he exhibited an inguinal bulge one month after the operation. He underwent laparoscopy, and a right femoral hernia was detected. The femoral hernia was laparoscopically repaired via two small incisions: a 1.0-cm umbilical incision for a 3-mm 30 degrees laparoscope and 3-mm grasping forceps and a 5-mm right lateral incision for 3-mm grasping forceps. After the hernia sac had been reflected into the abdominal cavity and resected, the iliopubic tract was sutured to Cooper's ligament using a laparoscopic percutaneous extracorporeal closure (LPEC) needle and 2-0 non-absorbable sutures. Laparoscopy enables the accurate diagnosis of rare and often missed pediatric femoral hernias. Our laparoscopic technique for treating femoral hernias is easy and effective. Although these early results are encouraging, more cases involving longer follow-up periods should be accumulated to confirm the efficacy of our technique.

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2015.07.008

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/ped.12529

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2014.0250

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.vaccine.2015.01.075

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.11477/mf.1413205164

CiNii Research

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：NAGOYA UNIV, SCH MED  

Gastric duplication cyst is a rare anomaly, and most cases are recognized during childhood. Recently, several pediatric cases with small gastric duplication cysts treated by laparoscopic resection have been reported. Here, we describe an infant in whom we successfully performed laparoscopic partial gastrectomy for the treatment of a huge gastric duplication cyst. To the best of our knowledge, this is the largest gastric duplication cyst treated by laparoscopic surgery among infants. We introduce our procedure and some tips.

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.4293/JSLS.2014.00238

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.3978/j.issn.2224-4336.2015.02.01

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Japan Surgical Association  

A baby girl delivered at the gestational age of 38 week's was referred to our department because of an intraabdominal cyst diagnosed prenatally. There were no specific symptoms after birth. USG revealed a cyst-like structure with gut signature, and CT showed a cystic mass in the abdomen containing air. A preoperative diagnosis of duplication of the alimentary tract or Meckel's diverticulum was made, and a laparoendoscopic single-site surgery was performed when the baby girl was ten months old. An inverted Y-shaped incision was made at the umbilicus, and laparoscopic exploration revealed a cystic mass sharing a common wall and blood supply with the ileum on the mesenteric side. We exteriorized the duplication cyst with normal ileum from the umbilical incision, and performed resection of the segment of the small bowel including the cystic mass. Histopathology revealed that the ileal duplication cyst was lined with gastric epithelium. The postoperative course was uneventful.

DOI： 10.3919/jjsa.76.529

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1155/2015/173014

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2014.0222

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-014-3575-x

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-014-3569-8

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00595-013-0605-6

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：NAGOYA UNIV, SCH MED  

Midgut volvulus is a highly life-threatening condition that carries a high risk of short gut syndrome. We report a case of catastrophic neonatal midgut volvulus in which second-look laparotomy revealed apparently non-viable remnant small intestine but with a moderate blood supply. Full-thickness small intestine necrosis was distributed in a patchy fashion, with non-viable and necrotic areas distributed so widely that no portion of the intestine could be resected. A section of full-thickness necrotic intestine preserved at surgery was able to regenerate, and normal function was restored over a period of 1 month. This case indicated that intestinal resumption may be dependent on blood flow. Even when intestinal viability is questionable, preservation enables the chance of regeneration if moderate blood flow is present.

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：一般社団法人日本外科学会  

CiNii Research

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

High-output heart failure in a neonate due to pulmonary sequestration is rare. We report a case of neonatal heart failure relieved with thoracoscopic resection of an intralobar pulmonary sequestration. A male neonate of 39-week gestational age presented with respiratory distress, chest X-ray and echocardiography revealed high-output heart failure. A computed tomography showed a left lower pulmonary sequestration with venous drainage into the azygos system. Preoperative diagnosis is an extralobar pulmonary sequestration, and high-output heart failure is caused by arteriovenous shunt in the pulmonary sequestration. We intervened with thoracoscopic resection on day-of-life 21. Intraoperative diagnosis is an intralobar pulmonary sequestration. Postoperative course was uneventful, and the patient was discharged on postoperative day 20 without any sign of heart failure.

DOI： 10.11164/jjsps.50.5_946

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2013.0180

Web of Science

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2013.08.010

Web of Science

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2013.0127

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-013-3383-8

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-013-3373-x

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2013.0110

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00595-012-0426-z

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1089/lap.2013.0130

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1111/j.1442-200X.2012.03663.x

Web of Science

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2012.08.028

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： doi: 10.1111/j.1442-200X.2012.03663.x.

PubMed

Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier Inc.  

Pediatric patients with large extraovarian teratomas with a significant solid component are usually treated using open surgery because the size of the intracorporeal cavity does not facilitate the manipulation of large tumors. Here, we describe the cases of 3 children who underwent minimally invasive surgery for large extraovarian teratomas (diameter &gt
10 cm), including 2 cases of retroperitoneal teratoma and 1 case of a thoracic teratoma. All tumors had a large amount of sebaceous material that displaced other surrounding organs. Tumor volumes were reduced by intraoperative needle aspiration using a SAND balloon catheter with a double balloon that is designed to minimize the risk of spillage. Intraoperative needle aspiration of cystic content can provide sufficient working space and facilitates safe separation of the major vessels from the tumor. Treatment of large extraovarian teratomas by minimally invasive surgery involving skin incisions that result in a less noticeable scar, such as a Pfannenstiel incision or axillary incision, can achieve improved cosmetic outcomes. © 2013 The Authors.

DOI： 10.1016/j.epsc.2013.07.003

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本小児血液・がん学会  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-012-3146-y

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00383-011-3008-z

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.7_1078_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.1_143_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_400_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_399_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_445_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_443_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_443_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_539_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_668_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_596_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_585_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.48.3_505_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：埼玉県医学会  

腹腔鏡下腎摘除術を施行した小児患者16例(男児4例、女児12例、中央値5歳)の成績を報告した。男児の基礎疾患はそれぞれ精嚢腺嚢胞と同側単純性尿管瘤合併、膀胱尿管逆流症と腎盂尿管移行部狭窄合併、単純性尿管瘤とMCDK合併、尿管異所開口であった。女児は全例尿管異所開口で、9例は開口部が同定不能であった。手術は患側を上にした半側臥位とし、3ポート或いは4ポートで行った。経腹腔的に腎に到達し、腎周囲を電気メス、超音波凝固切開装置を用いて剥離した。尿管と腎茎部の血管はエンドループ或いはクリップを用いて切離し、臍の創より腎臓を摘出した。手術時間は中央値120分、麻酔時間217分、出血量0mlで、術中合併症はなかった。術後在院日数は中央値5.5日で、精嚢腺嚢胞切除を併施した1例に術後尿閉を認め、一時的な間歇導尿を要したが自然に軽快した。病理組織学的にはhypoplastickidnyが多く、一部にrenal dysplasiaを伴うものも認めた。

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

1歳4ヵ月男児。出生時より右陰嚢が鼠径部に認められ、産院で異所性陰嚢と診断後、著者らの施設へ紹介来院となった。初診時、陰嚢右側は本来の位置から離れ右鼠径部にあり、内部には精巣が存在していた。一方、陰嚢左側と左精巣は正常の位置に存在しており、陰嚢正中に縫線が認められた。また他の体表奇形はみられず、腹部エコーでも泌尿生殖器系の異常は認められなかった。そこで、1歳4ヵ月目に手術が施行され、手術はZ形成術により右鼠径部の陰嚢を本来の位置に移動させた。その結果、合併症は認めず、術後5日目で退院となり、更に術後1ヵ月経過では右陰嚢の色調良好が確認された。尚、右精巣にも萎縮性変化は認められなかった。

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2010.09.097

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本腹部救急医学会  

腹腔鏡手術は低侵襲で整容的に優れるため,腹部救急疾患に対しても適応が拡大しつつある。当科では最近12年間に,急性虫垂炎・肥厚性幽門狭窄症を除く小児腹部救急疾患75例に対し腹腔鏡手術を行った。診断は腸閉塞17例,脳室腹腔シャント障害9例,卵巣・卵管捻転8例,Meckel憩室(腸閉塞を除く),横隔膜ヘルニア各7例等であった。診断確定目的の腹腔鏡を21例に行い6例は観察のみで終了した。新生児例は捻転のない腸回転異常症と卵巣嚢腫捻転の計3例であった。術中小腸損傷は2例(2.5%),開腹移行は4例(5.0%)あった。腹部救急疾患に対して腹腔鏡手術を行うには,迅速な開腹移行にも対応できる,チームとしての熟練が必要である。腹腔鏡手術の絶対的禁忌は全身麻酔・気腹のハイリスク例であり,相対的禁忌として腸管壊死を伴う絞扼性イレウスがあげられるが,その他の症例では腹腔鏡手術の適応を考慮できると考えられた。(著者抄録)

DOI： 10.11231/jaem.31.31

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_516_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_715_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_732_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_741_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_751_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_755_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_610_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_490_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.6_929_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_560_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_565_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_567_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_568_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_568_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_588_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_167_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_168_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_168_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_173_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_175_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.1_182_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.3_375_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.2_298_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.3_376_5

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.4_582_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.3_377_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.47.7_1094_2

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2010.08.037

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：埼玉県医学会  

2000年1月〜2009年12月に胸腔鏡補助下(VATS)12例および完全胸腔鏡下(CTL)肺葉切除3例について、手術成績・合併症などを後方視的に検討した。VATSとCTLにおける中央値はそれぞれ、手術時年齢5歳10ヵ月・1歳3ヵ月、手術時体重は17.8kg・9.5kg、手術時間は184分・222分、出血量は116g・28g、術後在院日数は8.5日・6日であった。VATSで1例が出血のため開胸移行したが、いずれも術後合併症は認めなかった。

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

2005年以降に腹腔鏡補助下肛門形成術(LAARP)を施行した28症例(男児22例、女児6例、手術時平均月齢6.5±3.1ヵ月)を対象に術式の問題点および術後の排便機能について後方視的に検討した。その結果、平均手術時間は194±61分、出血量は7.8±8.4mlで、早期合併症としては直腸肛門縫合不全が3例にみられ、1例は保存的に軽快、2例は再吻合を要した。晩期合併症としては大きな尿道後部嚢胞が3例にみられ、うち2例は嚢胞摘出標本に直腸粘膜がみられたことから、瘻孔切離部が直腸側に寄りすぎたため遺残瘻孔となり、徐々に増大したと考えられた。術後1年以上経過時に施行のMRIでは1.5cm以下の嚢胞が6例に認められたが、それらは2年以上経過しても増大傾向はみられなかった。排便機能は4歳時では1日おきに浣腸を行っている症例が多くみられたが、失禁はほとんどみられず時に汚染がみられる症例が多かった。7・8歳時では4歳時と比べ各項目で徐々に改善がみられ、便意と総合点では有意な改善が認められた。尚、肛門静止圧・肛門管長・直腸肛門弛緩反射についてはPSARPと差は認められなかった。

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2010.03.013

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2010.01.030

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本小児外科学会  

Other Link： https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2010&ichushi_jid=J01113&link_issn=&doc_id=20100602240204&doc_link_id=10.11164%2Fjjsps.46.3_524_2&url=https%3A%2F%2Fdoi.org%2F10.11164%2Fjjsps.46.3_524_2&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.6_911_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.3_701_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.3_520_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.3_524_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.3_550_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.3_560_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.1_136_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.6_1011_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.6_1004_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.6_995_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.6_1014_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.4_800_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.46.4_820_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本内視鏡外科学会  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本内視鏡外科学会  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(一社)日本内視鏡外科学会  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(NPO)日本小児がん学会  

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：(株)東京医学社  

1999〜2008年の10年間に著者等の施設における2500g未満の低出生体重児で外科手術を行った124症例(男児71例、女児53例)を対象に、出生体重・在胎週数・診断・予後について後方視的に検討した。その結果、平均在胎週数は34(21〜41)週、出生体重は平均1817(506〜2486)gで、出生体重の内訳は1000g未満の超低出生体重児25例、1000g以上1500g未満の極低出生体重児10例、1500g以上2500g未満の低出生体重児89例であった。疾病別では腸閉鎖・狭窄22例、消化管穿孔21例、直腸肛門奇形20例、食道閉鎖症16例、腸回転異常症8例、壊死性腸炎7例、臍帯ヘルニア6例、腹壁破裂5例、肥厚性幽門狭窄症4例、横隔膜ヘルニア・ヒルシュスプルング病・胆道閉鎖症各2例であった。出生前診断は124例中14例(11.2%)で、全国集計の26.7%より胎児診断率が低かった。予後では術後死亡率は13%(16例)で全国集計の16.2%と同等であった。

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2009.04.014

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：日本膵・胆管合流異常研究会  

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1055/s-2008-1038590

PubMed

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jpedsurg.2008.10.056

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.6_920_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_447_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_499_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_501_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_522_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_526_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.3_584_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.5_890_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_269_5

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_274_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_269_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_302_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.4_794_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_300_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.4_813_5

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.45.2_297_4

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1007/s00467-008-0839-5

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.transproceed.2008.01.047

Web of Science

Language：English   Publishing type：Research paper (scientific journal)   Publisher：ELSEVIER SCIENCE INC  

In Japan, organ donation has been still limited because of the strict donor criteria. The aim of this study was to show the effectiveness of pancreas transplantation (PTx) by analyzing the outcomes even under poor donor conditions. Thirty-six cases of PTx (32 simultaneous pancreas and kidney transplantations [SPK], 4 pancreas after kidney transplantations) performed during the last 8 years were examined especially for donor characteristics. Mean donor age of 41.4 +/- 11.9 years was considerably older compared with that in the United States and Europe; donors aged over 40 years comprised 67% of the total. According to the criteria described by Kapur, 29 cases (81%) in our series would be considered marginal. Thus, to increase blood supply into the pancreatic head, the gastroduodenal artery (GDA) was anastomosed using donor artery to common hepatic artery or iliac Y graft. These procedures were performed in 16 of the 24 cases in which there was liver procurement. Eventually, 34 cases (94%) preserved GDA continuity. Mean total cold ischemic time of pancreatic grafts was 12 hours 1.5 minutes. Of 214 registrants, 17 patients on the waiting list for SPK died of diabetic complications. To date, patient survival remains 100% with a mean follow-up period of 33 months. Pancreas graft survivals at 1, 3, and 5 years posttransplantation were 92%, 80%, and 80%, respectively. In contrast, kidney survivals were 91%, 91%, and 91%, respectively. The integrity of the pancreas head and duodenum by preservation of the GDA continuity might have decreased the risk associated with the marginal donors.

DOI： 10.1016/j.transproceed.2008.01-047

Web of Science

Scopus

Other Link： http://orcid.org/0000-0002-1818-6697

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.44.3_386

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.44.3_392_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.44.3_410_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.44.6_764_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.44.6_781_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.44.6_784_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.44.1_102_3

Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1053/j.sempedsurg.2007.06.008

PubMed

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：Japan Association for Medical Informatics  

Information and communication technology has been introduced rapidly into health-care field, and can contribute to system complexity and new human errors. Nielsen has defined 5 facets of usability: learnability, efficiency, memorability, errors and satisfaction. The more the usability progress, the more likely patient safety will be achieved, however, there is the trade-off relationship between safety ensuring and efficiency seeking. Technology needs to be designed and improved to support real workflow and care processes.

DOI： 10.14948/jami.27.29

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.43.3_373_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.43.3_452_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.43.3_573_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：The Japanese Society of Pediatric Surgeons  

DOI： 10.11164/jjsps.43.3_573_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.1_104_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.1_121_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.6_794_3

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.6_799_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.5_709_4

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.1_109_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.4_648_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.43.1_125_1

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.42.3_450_2

Language：Japanese   Publishing type：Research paper (scientific journal)   Publisher：特定非営利活動法人 日本小児外科学会  

DOI： 10.11164/jjsps.42.3_414_1