Effect of omega-3 fatty acids on cardiovascular events in high-risk patients with hypertriglyceridemia in Japan: a 3-year post-marketing surveillance study (OCEAN3 survey)

Teramoto Tamio, Ogawa Hisao, Ueshima Hirotsugu, Okada Yasushi, Haze Kazuo, Matsui Shigeyuki, Fujikawa Keita, Hashimoto Takamasa, Sakui Sho, Nishimura Kunihiko, Kajita Mika, Horimoto Atsushi, Fernandez Jovelle

EXPERT OPINION ON DRUG SAFETY   Vol. 22 ( 1 ) page： 81 - 90   2023.1

Blinded sample size re-estimation for comparing over-dispersed count data incorporating follow-up lengths

Igeta Masataka, Matsui Shigeyuki

STATISTICS IN MEDICINE   Vol. 41 ( 29 ) page： 5622 - 5644   2022.12

Bias correction based on weighted likelihood for conditional estimation of subgroup effects in randomized clinical trials

Toyoizumi Kiichiro, Matsui Shigeyuki

STATISTICS IN MEDICINE   Vol. 41 ( 26 ) page： 5276 - 5289   2022.11

Extended-spectrum antibiotics for community-acquired pneumonia with a low risk for drug-resistant pathogens

Kobayashi Hironori, Shindo Yuichiro, Kobayashi Daisuke, Sakakibara Toshihiro, Murakami Yasushi, Yagi Mitsuaki, Matsuura Akinobu, Sato Kenta, Matsui Kota, Emoto Ryo, Yagi Tetsuya, Saka Hideo, Matsui Shigeyuki, Hasegawa Yoshinori

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES   Vol. 124   page： 124 - 132   2022.11

Epicardial adipose tissue volume is associated with abdominal aortic aneurysm expansion

Kawai Yohei, Banno Hiroshi, Sato Tomohiro, Ikeda Shuta, Tsuruoka Takuya, Sugimoto Masayuki, Niimi Kiyoaki, Kodama Akio, Matsui Kota, Matsui Shigeyuki, Komori Kimihiro

JOURNAL OF VASCULAR SURGERY   Vol. 76 ( 5 ) page： 1253 - 1260   2022.11

Efficacy of Endoscopic Ultrasound-guided Celiac Plexus Neurolysis for Abdominal Pain in Patients With Unresectable Pancreatic Cancer: Network Meta-analysis of Randomized Controlled Trials.

Okita M, Otani K, Matsui S

Journal of clinical gastroenterology     2022.10

Who are the long-term survivors of recurrent ovarian carcinoma?: a retrospective analysis of a multicenter study

Yoshihara Masato, Mogi Kazumasa, Kitami Kazuhisa, Uno Kaname, Iyoshi Shohei, Tano Sho, Fujimoto Hiroki, Miyamoto Emiri, Yoshikawa Nobuhisa, Emoto Ryo, Matsui Shigeyuki, Kajiyama Hiroaki

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 27 ( 10 ) page： 1660 - 1668   2022.10

Systematic review and meta-analysis of celiac plexus neurolysis for abdominal pain associated with unresectable pancreatic cancer

Okita Muneyori, Otani Kazuki, Gibo Noriaki, Matsui Shigeyuki

PAIN PRACTICE   Vol. 22 ( 7 ) page： 652 - 661   2022.9

Effects of lymphocyte and neutrophil counts and their time courses on mortality in patients with postoperative pneumonia

Murakami Yasushi, Shindo Yuichiro, Sano Masahiro, Okumura Junya, Kobayashi Hironori, Sakakibara Toshihiro, Iguchi Mitsutaka, Takahashi Kunihiko, Yagi Tetsuya, Matsui Shigeyuki, Hasegawa Yoshinori

SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page： 14564   2022.8

Obesity contributes to the stealth peritoneal dissemination of ovarian cancer: a multi-institutional retrospective cohort study

Iyoshi Shohei, Sumi Asami, Yoshihara Masato, Kitami Kazuhisa, Mogi Kazumasa, Uno Kaname, Fujimoto Hiroki, Miyamoto Emiri, Tano Sho, Yoshikawa Nobuhisa, Emoto Ryo, Matsui Shigeyuki, Kajiyama Hiroaki

OBESITY   Vol. 30 ( 8 ) page： 1599 - 1607   2022.8

The finger-to-nose test improved diagnosis of cerebrovascular events in patients presenting with isolated dizziness in the emergency department

Nishida Kazuki, Usami Takuya, Matsumoto Nana, Nishikimi Mitsuaki, Takahashi Kunihiko, Matsui Shigeyuki

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 3 ) page： 621 - 629   2022.8

Machine learning prediction models for postpartum depression: A multicenter study in Japan

Matsuo Seiko, Ushida Takafumi, Emoto Ryo, Moriyama Yoshinori, Iitani Yukako, Nakamura Noriyuki, Imai Kenji, Nakano-Kobayashi Tomoko, Yoshida Shigeru, Yamashita Mamoru, Matsui Shigeyuki, Kajiyama Hiroaki, Kotani Tomomi

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH   Vol. 48 ( 7 ) page： 1775 - 1785   2022.7

Prediction of Prehospital Change of the Cardiac Rhythm From Nonshockable to Shockable in Out-of-Hospital Patients With Cardiac Arrest: A Post Hoc Analysis of a Nationwide, Multicenter, Prospective Registry

Emoto Ryo, Nishikimi Mitsuaki, Shoaib Muhammad, Hayashida Kei, Nishida Kazuki, Kikutani Kazuya, Ohshimo Shinichiro, Matsui Shigeyuki, Shime Nobuaki, Iwami Taku

JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 11 ( 12 ) page： e025048   2022.6

Risk factors for antibiotic resistance in hospital-acquired and ventilator-associated pneumonia

Sano Masahiro, Shindo Yuichiro, Takahashi Kunihiko, Okumura Junya, Sakakibara Toshihiro, Murakami Yasushi, Iguchi Mitsutaka, Yagi Tetsuya, Matsui Shigeyuki, Hasegawa Yoshinori

JOURNAL OF INFECTION AND CHEMOTHERAPY   Vol. 28 ( 6 ) page： 745 - 752   2022.6

Broad-Spectrum Antibiotics and Mortality in Community-Acquired Pneumonia Patients with Low-Risk for Drug-Resistant Pathogens

Kobayasi H., Shindo Y., Kobayashi D., Sakakibara T., Murakami Y., Yagi M., Matsuura A., Sato K., Goto Y., Matsui S., Yagi T., Saka H., Hasegawa Y.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE   Vol. 205   2022.5

Dynamic Risk Prediction via a Joint Frailty-Copula Model and IPD Meta-Analysis: Building Web Applications

Emura Takeshi, Michimae Hirofumi, Matsui Shigeyuki

ENTROPY   Vol. 24 ( 5 )   2022.5

A prediction rule for severe adverse events in all inpatients with community-acquired pneumonia: a multicenter observational study

Sakakibara Toshihiro, Shindo Yuichiro, Kobayashi Daisuke, Sano Masahiro, Okumura Junya, Murakami Yasushi, Takahashi Kunihiko, Matsui Shigeyuki, Yagi Tetsuya, Saka Hideo, Hasegawa Yoshinori

BMC PULMONARY MEDICINE   Vol. 22 ( 1 ) page： 34   2022.1

Clinical paper The rCAST score is useful for estimating the neurological prognosis in pediatric patients with post-cardiac arrest syndrome before ICU admission: External validation study using a nationwide prospective registry

Yasuda Yuma, Nishikimi Mitsuaki, Matsui Kota, Numaguchi Atsushi, Nishida Kazuki, Emoto Ryo, Matsui Shigeyuki, Matsuda Naoyuki

RESUSCITATION   Vol. 168   page： 103 - 109   2021.11

Hypofibrinogenemia can be estimated by the predictive formula in aortic surgery

Nishi Toshihiko, Mutsuga Masato, Akita Toshiaki, Narita Yuji, Fujimoto Kazuro, Tokuda Yoshiyuki, Nishida Kazuki, Matsui Shigeyuki, Nishiwaki Kimitoshi, Usui Akihiko

GENERAL THORACIC AND CARDIOVASCULAR SURGERY   Vol. 69 ( 10 ) page： 1376 - 1382   2021.10

Postoperative stroke and neurological outcomes in the early phase after revascularization surgeries for moyamoya disease: an age-stratified comparative analysis

Araki Yoshio, Yokoyama Kinya, Uda Kenji, Kanamori Fumiaki, Kurimoto Michihiro, Shiba Yoshiki, Mamiya Takashi, Nishihori Masahiro, Izumi Takashi, Sumitomo Masaki, Okamoto Sho, Matsui Kota, Emoto Ryo, Wakabayashi Toshihiko, Matsui Shigeyuki, Natsume Atsushi

NEUROSURGICAL REVIEW   Vol. 44 ( 5 ) page： 2785 - 2795   2021.10

Clinical impact of visually assessed right ventricular dysfunction in patients with septic shock

Hiraiwa Hiroaki, Kasugai Daisuke, Ozaki Masayuki, Goto Yukari, Jingushi Naruhiro, Higashi Michiko, Nishida Kazuki, Kondo Toru, Furusawa Kenji, Morimoto Ryota, Okumura Takahiro, Matsuda Naoyuki, Matsui Shigeyuki, Murohara Toyoaki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 18823   2021.9

Outcome Related to Level of Targeted Temperature Management in Postcardiac Arrest Syndrome of Low, Moderate, and High Severities: A Nationwide Multicenter Prospective Registry

Nishikimi Mitsuaki, Ogura Takayuki, Nishida Kazuki, Hayashida Kei, Emoto Ryo, Matsui Shigeyuki, Matsuda Naoyuki, Iwami Taku

CRITICAL CARE MEDICINE   Vol. 49 ( 8 ) page： E741 - E750   2021.8

A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer

Yoshihara Masato, Emoto Ryo, Kitami Kazuhisa, Iyoshi Shohei, Uno Kaname, Mogi Kazumasa, Tano Sho, Yoshikawa Nobuhisa, Matsui Shigeyuki, Kajiyama Hiroaki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 15154   2021.7

Relative platelet reductions provide better pathophysiologic signatures of coagulopathies in sepsis

Kasugai Daisuke, Ozaki Masayuki, Nishida Kazuki, Goto Yukari, Takahashi Kunihiko, Matsui Shigeyuki, Matsuda Naoyuki

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 14033   2021.7

The interplay between bystander cardiopulmonary resuscitation and ambient temperature on neurological outcome after cardiac arrest: A nationwide observational cohort study

Hayashida Kei, Takegawa Ryosuke, Nishikimi Mitsuaki, Aoki Tomoaki, Emoto Ryo, Shinozaki Koichiro, Miyara Santiago J., Rolston Daniel M., Li Timmy, Shoaib Muhammad, Fukuda Tatsuma, Molmenti Ernesto P., Suzuki Masaru, Sasaki Junichi, Matsui Shigeyuki, Becker Lance B.

RESUSCITATION   Vol. 164   page： 46 - 53   2021.7

Statistical Models in Clinical Studies

Matsui Shigeyuki, Le-Rademacher Jennifer, Mandrekar Sumithra J.

JOURNAL OF THORACIC ONCOLOGY   Vol. 16 ( 5 ) page： 734 - 739   2021.5

Semi-parametric empirical Bayes factor for genome-wide association studies

Morisawa Junji, Otani Takahiro, Nishino Jo, Emoto Ryo, Takahashi Kunihiko, Matsui Shigeyuki

EUROPEAN JOURNAL OF HUMAN GENETICS   Vol. 29 ( 5 ) page： 800 - 807   2021.5

Failure of non-invasive respiratory support after 6 hours from initiation is associated with ICU mortality

Nishikimi Mitsuaki, Nishida Kazuki, Shindo Yuichiro, Shoaib Muhammad, Kasugai Daisuke, Yasuda Yuma, Higashi Michiko, Numaguchi Atsushi, Yamamoto Takanori, Matsui Shigeyuki, Matsuda Naoyuki

PLOS ONE   Vol. 16 ( 4 ) page： e0251030   2021.4

Blinded Sample Size Re-Estimation in Comparative Clinical Trials With Overdispersed Count Data: Incorporation of Misspecification of the Variance Function

Igeta Masataka, Matsui Shigeyuki

STATISTICS IN BIOPHARMACEUTICAL RESEARCH   Vol. 13 ( 2 ) page： 170 - 180   2021.4

Prognostic value of desmoplastic reaction characterisation in stage II colon cancer: prospective validation in a Phase 3 study (SACURA Trial)

Ueno Hideki, Ishiguro Megumi, Nakatani Eiji, Ishikawa Toshiaki, Uetake Hiroyuki, Murotani Kenta, Matsui Shigeyuki, Teramukai Satoshi, Sugai Tamotsu, Ajioka Yoichi, Maruo Hirotoshi, Kotaka Masahito, Tsujie Masaki, Munemoto Yoshinori, Yamaguchi Takashi, Kuroda Hisashi, Fukunaga Mutsumi, Tomita Naohiro, Sugihara Kenichi

BRITISH JOURNAL OF CANCER   Vol. 124 ( 6 ) page： 1088 - 1097   2021.3

Does complete-staging lymphadenectomy improve survival outcomes in stage I endometrioid epithelial ovarian carcinoma? A multi-institutional retrospective study with propensity score-weighted analysis

Yoshihara Masato, Tamauchi Satoshi, Iyoshi Shohei, Kitami Kazuhisa, Uno Kaname, Tano Sho, Matsui Shigeyuki, Kajiyama Hiroaki

JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 51 ( 3 ) page： 387 - 392   2021.3

Effect-Size Estimation Using Semiparametric Hierarchical Mixture Models in Disease-Association Studies with Neuroimaging Data

Emoto Ryo, Kawaguchi Atsushi, Takahashi Kunihiko, Matsui Shigeyuki

COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE   Vol. 2020   page： 7482403   2020.12

Relationship Between Bone Mineral Density and Risk of Vertebral Fractures with Denosumab Treatment in Japanese Postmenopausal Women and Men with Osteoporosis

Okubo Naoki, Matsui Shigeyuki, Matsumoto Toshio, Sugimoto Toshitsugu, Hosoi Takayuki, Osakabe Taisuke, Watanabe Ko, Takami Hideo, Shiraki Masataka, Nakamura Toshitaka

CALCIFIED TISSUE INTERNATIONAL   Vol. 107 ( 6 ) page： 559 - 566   2020.12

Optimal Criteria for G3 (Poorly Differentiated) Stage II Colon Cancer Prospective Validation in a Randomized Controlled Study (SACURA Trial)

Ueno Hideki, Ishiguro Megumi, Nakatani Eiji, Ishikawa Toshiaki, Uetake Hiroyuki, Matsui Shigeyuki, Teramukai Satoshi, Murotani Kenta, Ajioka Yoichi, Shimazaki Hideyuki, Maeda Atsuyuki, Takuma Kunio, Yoshida Takefumi, Kambara Takeshi, Matsuda Keiji, Takagane Akinori, Tomita Naohiro, Sugihara Kenichi

AMERICAN JOURNAL OF SURGICAL PATHOLOGY   Vol. 44 ( 12 ) page： 1685 - 1698   2020.12

Desmoid with biweekly methotrexate and vinblastine shows similar effects to weekly administration: A phase II clinical trial

Nishida Yoshihiro, Hamada Shunsuke, Urakawa Hiroshi, Ikuta Kunihiro, Sakai Tomohisa, Koike Hiroshi, Ito Kan, Emoto Ryo, Ando Yuichi, Matsui Shigeyuki

CANCER SCIENCE   Vol. 111 ( 11 ) page： 4187 - 4194   2020.11

Maximum Norepinephrine Dosage Within 24 Hours as an Indicator of Refractory Septic Shock: A Retrospective Study

Kasugai Daisuke, Hirakawa Akihiko, Ozaki Masuyuki, Nishida Kazuki, Ikeda Takao, Takahashi Kunihiko, Matsui Shigeyuki, Uenishi Norimichi

JOURNAL OF INTENSIVE CARE MEDICINE   Vol. 35 ( 11 ) page： 1285 - 1289   2020.11

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Kumagai Shogo, Togashi Yosuke, Kamada Takahiro, Sugiyama Eri, Nishinakamura Hitomi, Takeuchi Yoshiko, Vitaly Kochin, Itahashi Kota, Maeda Yuka, Matsui Shigeyuki, Shibahara Takuma, Yamashita Yasuho, Irie Takuma, Tsuge Ayaka, Fukuoka Shota, Kawazoe Akihito, Udagawa Hibiki, Kirita Keisuke, Aokage Keiju, Ishii Genichiro, Kuwata Takeshi, Nakama Kenta, Kawazu Masahito, Ueno Toshihide, Yamazaki Naoya, Goto Koichi, Tsuboi Masahiro, Mano Hiroyuki, Doi Toshihiko, Shitara Kohei, Nishikawa Hiroyoshi

NATURE IMMUNOLOGY   Vol. 21 ( 11 ) page： 1346 - +   2020.11

Impact of uterus-preserving surgery on Stage I primary mucinous epithelial ovarian carcinoma: A multi-institutional study with propensity score-weighted analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Iyoshi Shohei, Yokoi Akira, Suzuki Shiro, Kawai Michiyasu, Nagasaka Tetsuro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS   Vol. 150 ( 2 ) page： 177 - 183   2020.8

High-flow nasal cannula therapy for acute respiratory failure in patients with interstitial pneumonia: a retrospective observational study.

Omote N, Matsuda N, Hashimoto N, Nishida K, Sakamoto K, Ando A, Nakahara Y, Nishikimi M, Higashi M, Matsui S, Hasegawa Y

Nagoya journal of medical science   Vol. 82 ( 2 ) page： 301 - 313   2020.5

Relationship Between Serum Norepinephrine Levels at ICU Admission and the Risk of ICU-Acquired Delirium: Secondary Analysis of the Melatonin Evaluation of Lowered Inflammation of ICU Trial.

Yasuda Y, Nishikimi M, Nishida K, Takahashi K, Numaguchi A, Higashi M, Matsui S, Matsuda N

Critical care explorations   Vol. 2 ( 2 ) page： e0082   2020.2

A single paravertebral injection via a needle vs. a catheter for the spreading to multiple intercostal levels: a randomized controlled trial

Fujii Tasuku, Shibata Yasuyuki, Ban Yasutaka, Shitaokoshi Akira, Takahashi Kunihiko, Matsui Shigeyuki, Nishiwaki Kimitoshi

JOURNAL OF ANESTHESIA   Vol. 34 ( 1 ) page： 72 - 78   2020.2

Prognostic impact of pelvic and para-aortic lymphadenectomy on clinically-apparent stage I primary mucinous epithelial ovarian carcinoma: a multi-institutional study with propensity score-weighted analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Iyoshi Shohei, Yokoi Akira, Suzuki Shiro, Kawai Michiyasu, Nagasaka Tetsuro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 50 ( 2 ) page： 145 - 151   2020.2

Diagnosis of central diabetes insipidus using a vasopressin radioimmunoassay during hypertonic saline infusion

Takagi Hiroshi, Hagiwara Daisuke, Handa Tomoko, Sugiyama Mariko, Onoue Takeshi, Tsunekawa Taku, Ito Yoshihiro, Iwama Shintaro, Goto Motomitsu, Suga Hidetaka, Banno Ryoichi, Takahashi Kunihiko, Matsui Shigeyuki, Arima Hiroshi

ENDOCRINE JOURNAL   Vol. 67 ( 3 ) page： 267 - 274   2020

More Powerful Selective Kernel Tests for Feature Selection

Lim Jen Ning, Yamada Makoto, Jitkrittum Wittawat, Terada Yoshikazu, Matsui Shigeyuki, Shimodaira Hidetoshi

INTERNATIONAL CONFERENCE ON ARTIFICIAL INTELLIGENCE AND STATISTICS, VOL 108   Vol. 108   page： 820 - 829   2020

A randomised controlled trial of pectoral nerve-2 (PECS 2) block vs. serratus plane block for chronic pain after mastectomy. Reviewed

Fujii T, Shibata Y, Akane A, Aoki W, Sekiguchi A, Takahashi K, Matsui S, Nishiwaki K

Anaesthesia   Vol. 74 ( 12 ) page： 1558 - 1562   2019.12

Clinical Frailty Scale Score Before ICU Admission Is Associated With Mobility Disability in Septic Patients Receiving Early Rehabilitation.

Nakajima H, Nishikimi M, Shimizu M, Hayashi K, Inoue T, Nishida K, Takahashi K, Matsui S, Nishida Y, Matsuda N

Critical care explorations   Vol. 1 ( 12 ) page： e0066   2019.12

Prognostic factors and effects of fertility-sparing surgery in women of reproductive age with ovarian clear-cell carcinoma: a propensity score analysis. Reviewed

Yoshihara M, Kajiyama H, Tamauchi S, Suzuki S, Takahashi K, Matsui S, Kikkawa F

J Gynecol Oncol   Vol. 30 ( 6 ) page： e102   2019.11

Prognostic factors and effects of fertility-sparing surgery in women of reproductive age with ovarian clear-cell carcinoma: a propensity score analysis

Yoshihara Masato, Kajiyama Hiroaki, Tamauchi Satoshi, Suzuki Shiro, Takahashi Kunihiko, Matsui Shigeyuki, Kikkawa Fumitaka

JOURNAL OF GYNECOLOGIC ONCOLOGY   Vol. 30 ( 6 ) page： e102   2019.11

Prospective Multicenter Study on the Prognostic and Predictive Impact of Tumor Budding in Stage II Colon Cancer: Results From the SACURA Trial. Reviewed

Ueno H, Ishiguro M, Nakatani E, Ishikawa T, Uetake H, Matsuda C, Nakamoto Y, Kotake M, Kurachi K, Egawa T, Yasumasa K, Murata K, Ikawa O, Shinji S, Murotani K, Matsui S, Teramukai S, Tomita N, Sugihara K

J Clin Oncol   Vol. 37 ( 22 ) page： 1886-1894   2019.8

Prospective Multicenter Study on the Prognostic and Predictive Impact of Tumor Budding in Stage II Colon Cancer: Results From the SACURA Trial

Ueno Hideki, Ishiguro Megumi, Nakatani Eiji, Ishikawa Toshiaki, Uetake Hiroyuki, Matsuda Chu, Nakamoto Yoshihiko, Kotake Masanori, Kurachi Kiyotaka, Egawa Tomohisa, Yasumasa Keigo, Murata Kohei, Ikawa Osamu, Shinji Seiichi, Murotani Kenta, Matsui Shigeyuki, Teramukai Satoshi, Tomita Naohiro, Sugihara Kenichi

JOURNAL OF CLINICAL ONCOLOGY   Vol. 37 ( 22 ) page： 1886 - +   2019.8

Two-stage analysis for selecting fixed numbers of features in omics association studies. Reviewed

Kawabata T, Emoto R, Nishino J, Takahashi K, Matsui S

Stat Med   Vol. 38 ( 16 ) page： 2956-2971   2019.7

Two-stage analysis for selecting fixed numbers of features in omics association studies

Kawabata Takanori, Emoto Ryo, Nishino Jo, Takahashi Kunihiko, Matsui Shigeyuki

STATISTICS IN MEDICINE   Vol. 38 ( 16 ) page： 2956 - 2971   2019.7

Steeper Macular Curvature in Eyes With Non-Highly Myopic Retinitis Pigmentosa. Reviewed

Komori S, Ueno S, Ito Y, Sayo A, Meinert M, Kominami T, Inooka D, Kitagawa M, Nishida K, Takahashi K, Matsui S, Terasaki H

Invest Ophthalmol Vis Sci   Vol. 60 ( 8 ) page： 3135-3141   2019.7

Statistical testing strategies for assessing treatment efficacy and marker accuracy in phase III trials Reviewed

Nonaka T, Igeta M, Matsui S

Pharm Stat   Vol. 18 ( 4 ) page： 459-475   2019.7

External validation of a risk classification at the emergency department of post-cardiac arrest syndrome patients undergoing targeted temperature management. Reviewed

Nishikimi M, Ogura T, Nishida K, Takahashi K, Nakamura M, Matsui S, Matsuda N, Iwami T

Resuscitation   ( 140 ) page： 135-141   2019.7

Novel multi-gene classifier for prediction of relapse-free survival after FU-based adjuvant chemotherapy for stage III colon cancer: A biomarker study of the ACTS-C trial, a randomized controlled study

Ishikawa Toshiaki, Murotani Kenta, Ishiguro Megumi, Nakatani Eiji, Uetake Hiroyuki, Matsui Shigeyuki, Sugihara Kenichi

CANCER RESEARCH   Vol. 79 ( 13 )   2019.7

External validation of a risk classification at the emergency department of post-cardiac arrest syndrome patients undergoing targeted temperature management

Nishikimi Mitsuaki, Ogura Takayuki, Nishida Kazuki, Takahashi Kunihiko, Nakamura Mitsunobu, Matsui Shigeyuki, Matsuda Naoyuki, Iwami Taku

RESUSCITATION   Vol. 140   page： 135 - 141   2019.7

Statistical testing strategies for assessing treatment efficacy and marker accuracy in phase III trials

Nonaka Takahiro, Igeta Masataka, Matsui Shigeyuki

PHARMACEUTICAL STATISTICS   Vol. 18 ( 4 ) page： 459 - 475   2019.7

Steeper Macular Curvature in Eyes With Non-Highly Myopic Retinitis Pigmentosa

Komori Shiori, Ueno Shinji, Ito Yasuki, Sayo Akira, Meinert Monika, Kominami Taro, Inooka Daiki, Kitagawa Masahiro, Nishida Kazuki, Takahashi Kunihiko, Matsui Shigeyuki, Terasaki Hiroko

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   Vol. 60 ( 8 ) page： 3135 - 3141   2019.7

Maximum norepinephrine dosage within 24 hours as an indicator of refractory septic shock: A retrospective study.

Kasugai D, Hirakawa A, Ozaki M, Nishida K, Ikeda T, Takahashi K, Matsui S, Uenishi N

J Intensive Care Med     page： 885066619860736   2019.6

Timing of administration of epinephrine predicts the responsiveness to epinephrine in norepinephrine-refractory septic shock: a retrospective study. Reviewed

Kasugai D, Nishikimi M, Nishida K, Higashi M, Yamamoto T, Numaguchi A, Takahashi K, Matsui S, Matsuda N

J Intensive Care   Vol. 7   page： 20   2019.4

Timing of administration of epinephrine predicts the responsiveness to epinephrine in norepinephrine-refractory septic shock: a retrospective study

Kasugai Daisuke, Nishikimi Mitsuaki, Nishida Kazuki, Higashi Michiko, Yamamoto Takanori, Numaguchi Atsushi, Takahashi Kunihiko, Matsui Shigeyuki, Matsuda Naoyuki

JOURNAL OF INTENSIVE CARE   Vol. 7   page： 20   2019.4

Hokuriku Liver Study Group. Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells. Reviewed

Sakai Y, Honda M, Matsui S, Komori O, Murayama T, Fujiwara T, Mizuno M, Imai Y, Yoshimura K, Nasti A, Wada T, Iida N, Kitahara M, Horii R, Toshikatsu T, Nishikawa M, Okafuji H, Mizukoshi E, Yamashita T, Yamashita T, Arai K, Kitamura K, Kawaguchi K, Takatori H, Shimakami T, Terashima T, Hayashi T, Nio K, Kaneko S

Cancer Sci   Vol. 110 ( 4 ) page： 1364-1388   2019.4

Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells

Sakai Yoshio, Honda Masao, Matsui Shigeyuki, Komori Osamu, Murayama Toshinori, Fujiwara Tadami, Mizuno Masaaki, Imai Yasuhito, Yoshimura Kenichi, Nasti Alessandro, Wada Takashi, Iida Noriho, Kitahara Masaaki, Horii Rika, Toshikatsu Tamai, Nishikawa Masashi, Okafuji Hirofumi, Mizukoshi Eishiro, Yamashita Tatsuya, Yamashita Taro, Arai Kuniaki, Kitamura Kazuya, Kawaguchi Kazunori, Takatori Hajime, Shimakami Tetsuro, Terashima Takeshi, Hayashi Tomoyuki, Nio Kouki, Kaneko Shuichi

CANCER SCIENCE   Vol. 110 ( 4 ) page： 1364 - 1388   2019.4

[Na+] Increases in body fluids sensed by central Nax induce sympathetically mediated blood pressure elevations via H+-dependent activation of ASIC1a Reviewed

Nomura K, Hiyama TY, Sakuta H, Matsuda T, Lin CH, Kobayashi K, Kobayashi K, Kuwaki T, Takahashi K, Matsui S, Noda M

Neuron   Vol. 101 ( 1 ) page： 60 - +   2019.1

Exploring predictive biomarkers from clinical genome-wide association studies via multidimensional hierarchical mixture models. Reviewed

Otani T, Noma H, Sugasawa S, Kuchiba A, Goto A, Yamaji T, Kochi Y, Iwasaki M, Matsui S, Tsunoda T.

European Journal of Human Genetics   Vol. 27 ( 1 ) page： 140 - 149   2019.1

compound.Cox: univariate feature selection and compound covariate for predicting survival. Reviewed

Emura T, Matsui S, Chen HY.

Computer Methods and Programs in Biomedicine   Vol. 168 ( 1 ) page： 21 - 37   2019.1

A Model-Based Framework for Voxel and Region Level Inferences in Neuroimaging Disease-Association Studies

Emoto Ryo, Kawaguchi Atsushi, Otani Takahiro, Matsui Shigeyuki

16TH INTERNATIONAL CONFERENCE ON INFORMATION TECHNOLOGY-NEW GENERATIONS (ITNG 2019)   Vol. 800   page： 367 - 372   2019

Rule-Based Designs Considering Toxicity Alone

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 9 - 32   2019

Model-Based Designs Considering Toxicity Alone

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 33 - 79   2019

Model-Assisted Designs Considering Toxicity Alone

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 81 - 94   2019

Early-Phase Cancer Clinical Trials

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 1 - 8   2019

Dose-Finding Designs for Early-Phase Cancer Clinical Trials A Brief Guidebook to Theory and Practice Preface

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： VII - VIII   2019

Designs for Early-Phase Immunotherapeutic Agent Trials

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 121 - 133   2019

Designs Considering Toxicity and Efficacy

Daimon Takashi, Hirakawa Akihiro, Matsui Shigeyuki

DOSE-FINDING DESIGNS FOR EARLY-PHASE CANCER CLINICAL TRIALS: A BRIEF GUIDEBOOK TO THEORY AND PRACTICE     page： 95 - 120   2019

Application of the Multi-Dimensional Hierarchical Mixture Model to Cross-Disorder Genome-Wide Association Studies

Otani Takahiro, Nishino Jo, Emoto Ryo, Matsui Shigeyuki

16TH INTERNATIONAL CONFERENCE ON INFORMATION TECHNOLOGY-NEW GENERATIONS (ITNG 2019)   Vol. 800   page： 361 - 366   2019

A New Scoring System for Predicting Adverse Events in Hospitalized Patients with Community-Onset Pneumonia

Sakakibara T., Shindo Y., Takahashi K., Kobayashi D., Okumura J., Sano M., Murakami Y., Thabet N., Kobayashi H., Yagi T., Matsui S., Saka H., Hasegawa Y.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE   Vol. 199   2019

Power and sample size calculation incorporating misspecifications of the variance function in comparative clinical trials with over-dispersed count data. Reviewed

Igeta M, Takahashi K, Matsui S

  Vol. 74 ( 4 ) page： 1459 - 1467   2018.12

Comprehensive Search for Prognostic Biomarkers using PCAWG Data

Kato Mamoru, Nagai Momoko, Hasegawa Takanori, Imoto Seiya, Matsui Shigeyuki, Tsunoda Tatsuhiko, Shibata Tatsuhiro

CANCER SCIENCE   Vol. 109   page： 291 - 291   2018.12

Sleep, the Missing Link? Reply

Nishikimi Mitsuaki, Numaguchi Atsushi, Takahashi Kunihiko, Matsui Shigeyuki, Matsuda Naoyuki

CRITICAL CARE MEDICINE   Vol. 46 ( 12 ) page： E1225 - E1226   2018.12

Two-stage approach based on zone and dose findings for two-agent combination Phase I/II trials

Shimamura Fumiya, Hamada Chikuma, Matsui Shigeyuki, Hirakawa Akihiro

JOURNAL OF BIOPHARMACEUTICAL STATISTICS   Vol. 28 ( 6 ) page： 1025 - 1037   2018.11

The authors reply. Reviewed

Nishikimi M, Numaguchi A, Takahashi K, Matsui S, Matsuda N

Critical Care Medicine   Vol. 46 ( 10 ) page： E1010 - E1011   2018.10

Prognostic impact of MSI and 18qLOH in stage II colon cancer: A prospective biomarker study in the SACURA trial

Ishikawa T., Ishiguro M., Nakatani E., Ueno H., Uetake H., Murotani K., Matsui S., Tomita N., Shimada Y., Takahashi K., Kotake K., Watanabe M., Mochizuki H., Teramukai S., Sugihara K.

ANNALS OF ONCOLOGY   Vol. 29   2018.10

Treatment of patients with sepsis in a closed intensive care unit is associated with improved survival: a nationwide observational study in Japan. Reviewed

Ogura T, Nakamura Y, Takahashi K, Nishida K, Kobashi D, Matsui S

Journal of Intensive Care 6   Vol. 6   page： 57   2018.9

Personalized dynamic prediction of death according to tumour progression and high-dimensional genetic factors: Meta-analysis with a joint model. Reviewed

Emura T, Nakatochi M, Matsui S, Michimae H, Rondeau V

Statistical Methods in Medical Research   Vol. 27 ( 9 ) page： 2842 - 2858   2018.9

Preoperative six-minute walk distance is associated with postoperative cognitive dysfunction. Reviewed

Hayashi K, Oshima H, Shimizu M, Kobayashi K, Matsui S, Nishida Y, Usui A

Annals of Thoracic Surgery   Vol. 106 ( 2 ) page： 505 - 512   2018.8

Effect of administration of ramelteon, a melatonin receptor agonist, on the duration of stay in the ICU: A single-center randomized placebo-controlled trial. Reviewed

Nishikimi M, Numaguchi A, Takahashi K, Miyagawa Y, Matsui K, Higashi M, Makishi G, Matsui S, Matsuda N

Critical Care Medicine   Vol. 46 ( 7 ) page： 1099 - 1105   2018.7

Differential effect of mild therapeutic hypothermia depending on the findings of hypoxic encephalopathy on early CT images in patients with post-cardiac arrest syndrome. Reviewed

Nishikimi M, Ogura T, Nishida K, Takahashi K, Fukaya K, Liu K, Nakamura M, Matsui S, Matsuda N

Resuscitation   Vol. 128   page： 11 - 15   2018.7

Re-assessment of multiple testing strategies for more efficient genome-wide association studies. Reviewed

Otani T, Noma H, Nishino J, Matsui S

European Journal of Human Genetics   Vol. 26 ( 7 ) page： 1038 - 1048   2018.7

Sample Size for Successful Genome-Wide Association Study of Major Depressive Disorder

Nishino Jo, Ochi Hidenori, Kochi Yuta, Tsunoda Tatsuhiko, Matsui Shigeyuki

FRONTIERS IN GENETICS   Vol. 9   page： 227   2018.6

Sample size for successful genome-wide association study of major depressive disorder. Reviewed

Nishino J, Ochi H, Kochi Y, Tsunoda T, Matsui S.

Frontiers in Genetics   Vol. 9   page： 227   2018.6

The current state of therapeutic development for rare cancers in Japan, and proposals for improvement. Reviewed

Kawai A, Goto T, Shibata T, Tani K, Mizutani S, Nishikawa A, Shibata T, Matsumoto S, Nagata K, Narukawa M, Matsui S, Ando M, Toguchida J, Monden M, Heike T, Kimura S, Ueda R

Cancer Science   Vol. 109 ( 5 ) page： 1731 - 1737   2018.5

Mortality in patients with community-onset pneumonia at low risk of drug-resistant pathogens: Impact of -lactam plus macrolide combination therapy

Okumura Junya, Shindo Yuichiro, Takahashi Kunihiko, Sano Masahiro, Sugino Yasuteru, Yagi Tetsuya, Taniguchi Hiroyuki, Saka Hideo, Matsui Shigeyuki, Hasegawa Yoshinori

RESPIROLOGY   Vol. 23 ( 5 ) page： 526 - 534   2018.5

Accuracy of the first interpretation of early brain CT images for predicting the prognosis of post-cardiac arrest syndrome patients at the emergency department. Reviewed

Nishikimi M, Ogura T, Matsui K, Takahashi K, Fukaya K, Liu K, Morita H, Nakamura M, Matsui S, Matsuda N

Journal of Intensive Care 6   Vol. 6   page： 26   2018.4

Empirical Bayes estimation of semi-parametric hierarchical mixture models for unbiased characterization of polygenic disease architectures. Reviewed

Nishino J, Kochi Y, Shigemizu D, Kato M, Ikari K, Ochi H, Noma H, Matsui K, Morizono T, Boroevich K, Tsunoda T, Matsui S

Frontiers in Genetics   Vol. 9   page： 115   2018.4

Biomarker-Stratified Phase III Clinical Trials: Enhancement with a Subgroup-Focused Sequential Design

Matsui Shigeyuki, Crowley John

CLINICAL CANCER RESEARCH   Vol. 24 ( 5 ) page： 994 - 1001   2018.3

Multi-subgroup gene screening using semi-parametric hierarchical mixture models and the optimal discovery procedure: Application to a randomized clinical trial in multiple myeloma

Matsui Shigeyuki, Noma Hisashi, Qu Pingping, Sakai Yoshio, Matsui Kota, Heuck Christoph, Crowley John

BIOMETRICS   Vol. 74 ( 1 ) page： 313 - 320   2018.3

オミクス研究における検証的解析と探索的解析：多重検定とP値を中心に Reviewed

松井　茂之

計量生物学   Vol. 38 ( 2 ) page： 127-139   2018

A dose-response meta-analysis to coffee consumption and colorectal cancer risk in the Japanese population: Application of a cubic-spline model. Reviewed

Horisaki K, Takahashi K, Ito H, Matsui S

Journal of Epidemiology   Vol. 28 ( 12 ) page： 503 - 509   2018

Immune condition of colorectal cancer patients featured by serum chemokines and gene expressions of CD4+ cells in blood. Reviewed

Komura T, Yano M, Miyake A, Takabatake H, Miyazawa M, Ogawa N, Seki A, Honda M, Wada T, Matsui S, Kaneko S, Sakai Y.

Canadian Journal of Gastroenterology and Hepatology   Vol. 2018   page： 7436205   2018

Global overexpression of divalent metal transporter 1 delays crocidolite-induced mesothelial carcinogenesis in male mice. Reviewed

Funahashi S, Okazaki Y, Nishiyama T, Ohyoshi H, Yasui H, Nishida K, Matsui S, Toyokuni S

Free Radical Research   Vol. 52 ( 9 ) page： 1030 - 1039   2018

Modern Dose-Finding Designs for Cancer Phase I Trials: Drug Combinations and Molecularly Targeted Agents Preface

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： VII - VIII   2018

High-Flow Nasal Cannula Therapy for Acute Respiratory Failure in Patients with Interstitial Pneumonia: A Retrospective Observational Study

Omote N., Hashimoto N., Matsuda N., Nishida K., Sakamoto K., Ando A., Nakahara Y., Nishikimi M., Higashi M., Matsui S., Hasegawa Y.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE   Vol. 197   2018

Dose Finding in Phase I Cancer Trials

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： 1 - 7   2018

Dose Finding for Molecularly Targeted Agents (MTAs)

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： 59 - 80   2018

Dose Finding for Joint Assessment of Both Efficacy and Toxicity

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： 41 - 58   2018

Dose Finding for a Combination of Two Agents

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： 9 - 40   2018

Advanced Topics on Dose-Finding Designs

Hirakawa Akihiro, Sato Hiroyuki, Daimon Takashi, Matsui Shigeyuki

MODERN DOSE-FINDING DESIGNS FOR CANCER PHASE I TRIALS: DRUG COMBINATIONS AND MOLECULARLY TARGETED AGENTS     page： 81 - 89   2018

Longitudinal study of visual field changes determined by Humphrey Field Analyzer 10-2 in patients with Retinitis Pigmentosa. Reviewed

Sayo A, Ueno S, Kominami T, Nishida K, Inooka D, Nakanishi A, Yasuda S, Okado S, Takahashi K, Matsui S, Terasaki H.

Sci Rep   Vol. 7 ( 1 ) page： 16383   2017.11

IMPLICATION OF beta-LACTAM PLUS MACROLIDE COMBINATION THERAPY ON MORTALITY IN PATIENTS WITH COMMUNITY-ONSET PNEUMONIA AT LOW RISK FOR DRUG-RESISTANT PATHOGENS

Okumura Junya, Shindo Yuichiro, Sano Masahiro, Sakakibara Toshihiro, Matsuda Toshiaki, Takahashi Kunihiko, Saka Hideo, Matsui Shigeyuki, Hasegawa Yoshinori

RESPIROLOGY   Vol. 22   page： 271 - 271   2017.11

Daple Coordinates Planar Polarized Microtubule Dynamics in Ependymal Cells and Contributes to Hydrocephalus. Reviewed

Takagishi M, Sawada M, Ohata S, Asai N, Enomoto A, Takahashi K, Weng L, Ushida K, Ara H, Matsui S, Kaibuchi K, Sawamoto K, Takahashi M

Cell Rep   Vol. 20 ( 4 ) page： 960 - 972   2017.7

An efficient and flexible test for rare variant effects. Reviewed

Sugasawa S, Noma H, Otani T, Nishino J, Matsui S

Eur J Hum Genet   Vol. 25 ( 6 ) page： 752 - 757   2017.6

A novel scoring system for predicting the neurologic prognosis prior to the initiation of induced hypothermia in cases of post-cardiac arrest syndrome: the CAST score Reviewed

Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T, Higashi M, Umino H, Makishi G, Numaguchi A, Matsushima S, Tokuyama H, Nakamura M, Matsui S

Scand J Trauma Resusc Emerg Med   Vol. 25 ( 1 ) page： 49   2017.5

Quantifying indirect evidence in network meta-analysis Reviewed

Noma H, Tanaka S, Matsui S, Cipriani A, Furukawa TA

Statistics in Medicine   Vol. 36 ( 6 ) page： 917-927   2017.3

Quantifying indirect evidence in network meta-analysis

Noma Hisashi, Tanaka Shiro, Matsui Shigeyuki, Cipriani Andrea, Furukawa Toshi A.

STATISTICS IN MEDICINE   Vol. 36 ( 6 ) page： 917 - 927   2017.3

Correcting estimation bias in randomized clinical trials with a test of treatment-by-biomarker interaction Reviewed

Toyoizumi K, Matsui S

Statistics in Biopharmaceutical Research   Vol. 9 ( 2 ) page： 172 - 179   2017

Risk Factors For Severe Adverse Outcomes In Patients With Hospital-Acquired Pneumonia

Sano M., Shindo Y., Okumura J., Sakakibara T., Matsuda T., Yagi T., Matsui K., Takahashi K., Matsui S., Hasegawa Y.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE   Vol. 195   2017

CAST: a new score for early prediction of neurological outcomes after cardiac arrest before therapeutic hypothermia with high accuracy Reviewed

Nishikimi M, Matsuda N, Matsui K, Takahashi K, Ejima T, Liu K, Ogura T, Higashi M, Umino H, Makishi G, Numaguchi A, Matsushima S, Tokuyama H, Nakamura M, Matsui S

Intensive Care Med   Vol. 42 ( 12 ) page： 2106-2107   2016.12

Genome-wide DNA copy-number analysis in ACTS-CC trial of adjuvant chemotherapy for stage III colonic cancer Reviewed

Ishikawa T, Uetake H, Murotani K, Kobunai T, Ishiguro M, Matsui S, Sugihara K

Anticancer Res   Vol. 36 ( 3 ) page： 853-860   2016.3

Association between photoreceptor regeneration and visual acuity following surgery for rhegmatogenous retinal detachment Reviewed

Kobayashi M, Iwase T, Yamamoto K, Ra E, Murotani K, Matsui S, Terasaki H

Invest Ophthalmol Vis Sci.   Vol. 57 ( 3 ) page： 889-898   2016.3

A comparative study of adaptive dose-finding designs for phase I oncology trials of combination therapies Reviewed

Hirakawa A, Wages NA, Sato H, Matsui S

Statistics in Medicine   Vol. 34 ( 24 ) page： 3194-3213   2015.10

Operative wound-related complications after cranial revascularization surgeries Reviewed

Takanari K, Araki Y, Okamoto S, Sato H, Yagi S, Toriyama K, Yokoyama K, Murotani K, Matsui S, Wakabayashi T, Kamei Y

J Neurosurg     2015.7

Sex-Related Differences in Ocular Blood Flow of Healthy Subjects Using Laser Speckle Flowgraphy Reviewed

Yanagida K, Iwase T, Yamamoto K, Ra E, Kaneko H, Murotani K, Matsui S, Terasaki H

Invest Ophthalmol Vis Sci   Vol. 56 ( 8 ) page： 4880-4890   2015.7

Estimation of treatment effects in all-comers randomized clinical trials with a predictive marker. Biometrics Reviewed

Choai Y, Matsui S

Biometrics   Vol. 71 ( 1 ) page： 25-32   2015.3

Idiopathic sudden sensorineural hearing loss in Japan. Reviewed

Nakashima T, Sato H, Gyo K, Hato N, Yoshida T, Shimono M, Teranishi M, Sone M, Fukunaga Y, Kobashi G, Takahashi K, Matsui S, Ogawa K

Acta Otolaryngol     page： 1158-63   2014.11

Clinical Trials Express: fracture risk reduction with denosumab in Japanese postmenopausal women and men with osteoporosis: denosumab fracture intervention randomized placebo controlled trial (DIRECT).

Nakamura T, Matsumoto T, Sugimoto T, Hosoi T, Miki T, Gorai I, Yoshikawa H, Tanaka Y, Tanaka S, Sone T, Nakano T, Ito M, Matsui S, Yoneda T, Takami H, Watanabe K, Osakabe T, Shiraki M, Fukunaga M

J Clin Endocrinol Metab     page： 2599-607   2014.7

Comparison of statistical analysis plans in randomize-all phase III trials with a predictive biomarker.

Matsui S, Choai Y, Nonaka T

Clin Cancer Res     page： 2820-30   2014.6

Response to letter to the editor by Dr Wages et al. Stat Med.

Hirakawa A, Matsui S

Stat Med     page： 2159-60   2014.5

Distinct cancer-specific survival in metastatic prostate cancer patients classified by a panel of single nucleotide polymorphisms of cancer-associated genes.

Tsuchiya N, Matsui S, Narita S, Kamba T, Mitsuzuka K, Hatakeyama S, Horikawa Y, Inoue T, Saito S, Ohyama C, Arai Y, Ogawa O, Habuchi T

Genes Cancer     page： 54-60   2013.1

Cancer outlier analysis based on mixture modeling of gene expression data.

Mori K, Oura T, Noma H, Matsui S

Computational and Mathematical Methods in Medicine     page： Article ID: 693901   2013

An empirical Bayes optimal discovery procedure based on semiparametric hierarchical mixture models.

Noma H, Matsui S

Computational and Mathematical Methods in Medicine     page： Article ID: 568480   2013

Genomic biomarkers for personalized medicine: development and validation in clinical studies.

Matsui S

Computational and Mathematical Methods in Medicine     page： Article ID: 865980   2013

Empirical Bayes ranking and selection methods via semiparametric hierarchical mixture models in microarray studies.

Statistics in Medicine   Vol. 32   page： 1904-1916   2013

Nested case control study of proteomic biomarkers for interstitial lung disease in Japanese patients with non-small-cell lung cancer treated with erlotinib: a multicenter phase 4 study (JO21661)

Atagi S, Katakami N, Yoshioka H, Fukuoka M, Kudoh S, Ogiwara A, Imai M, Ueda M, Matsui S

Clinical Lung Cancer   Vol. 14   page： 407-417   2013

Meta-analysis of oro-cecal transit time in fasting subjects

Kokubo T, Matsui S, Ishiguro M

Pharmaceutical Research   Vol. 30   page： 402-411   2013

A dose finding approach based on shrunken predictive probability for combinations of two agents in phase I trials

Hirakawa A, Hamada C, Matsui S

Statistics in Medicine   Vol. 32   page： 4515-4525   2013

Developing and validating continuous genomic signatures in randomized clinical trials for predictive medicine.

Matsui S, Simon R, Qu P, Shaughnessy J, Barlogie B, Crowley J

Clinical Cancer Research   Vol. 18   page： 6065-6073   2012

The optimal discovery procedure in multiple significance testing: an empirical Bayes approach.

Statistics in Medicine   Vol. 31   page： 165-176   2012

Endoscopic evaluation of non-steroidal anti-inflammatory drug (NSAID)-induced gastric and duodenal ulcers during prophylaxis with lansoprazole

Sakaki N, Ashida K, Mizokami Y, Asaka M, Matsui S, Kanto T, Hiraishi H, Hiramatsu N, Sugano K

Journal of Gastroenterology and Hepatology Research   Vol. 1   page： 260-265   2012

Study protocol of the SACURA trial: a randomized phase III trial of efficacy and safety of UFT as adjuvant chemotherapy for stage II colon cancer

Ishiguro M, Mochizuki H, Tomita N, Shimada Y, Takahashi K, Kotake K, Watanabe M, Kanemitsu Y, Ueno H, Ishikawa T, Uetake H, Matsui S, Teramukai S, Sugihara K

BMC Cancer   Vol. 12   page： 281   2012

Involvement of urinary bladder Connexin43 and the circadian clock in coordination of diurnal micturition rhythm

Negoro H, Kanematsu A, Doi M, Suadicani SO, Matsuo M, Imamura M, Okinami T, Nishikawa N, Oura T, Matsui S, Seo K, Tainaka M, Urabe S, Kiyokage E, Todo T, Okamura H, Tabata Y, Ogawa O

Nature Communications   Vol. 3   page： 809   2012

Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: Results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial

Sugano K, Kontani T, Katsuo S, Takei Y, Sakaki N, Ashida K, Mizokami Y, Asaka M, Matsui S, Kanto T, Soen S, Takeuchi T, Hiraishi H, Hiramatsu N

Journal of Gastroenterology   Vol. 47   page： 540-552   2012

Estimating effect sizes of differentially expressed genes for power and sample size assessments in microarray experiments.

Matsui S, Noma H

Biometrics   Vol. 67   page： 1225-1235   2011

Estimation and selection in high-dimensional genomic studies for developing molecular diagnostics.

Matsui S, Noma H

Biostatistics   Vol. 12   page： 223-233   2011

Population pharmacokinetics of pregabalin in healthy subjects and patients with postherpetic neuralgia or diabetic peripheral neuropathy

Shoji S, Suzuki M, Tomono Y, Bockbrader HN, Matsui S

British Journal of Clinical Pharmacology   Vol. 72   page： 63-76   2011

Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: Results of a prospective, multicenter, double-blind, randomized, double-dummy, active-control trial

Sugano K, Matsumoto Y, Itabashi T, Abe S, Sakaki N, Ashida K, Mizokami Y, Chiba T, Matsui S, Kanto T, Shimada K, Uchiyama S, Uemura N, Hiramatsu N. for the Lansoprazole Ulcer Prevention Study Group (Low-Dose Aspirin Therapy)

Journal of Gastoroenterogy   Vol. 46   page： 724-735   2011

Bayesian ranking and selection methods using hierarchical mixture models in microarray studies.

Biostatistics   Vol. 11   page： 281-289   2010

Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling

Matsumura N, Mandai M, Okamoto T, Yamaguchi K, Yamamura S, Oura T, Baba T, Hamanishi J, Kang HS, Matsui S, Mori S, Murphy SK, Konishi I

Cancer Science   Vol. 101   page： 2658-2663   2010

Medical mushrooms used for biochemical failure after radical treatment for prostate cancer: An open-label study

Yoshimura K, Kamoto T, Ogawa O, Matsui S, Tsuchiya N, Tada H, Murata K, Yoshimura K, Habuchi T, Fukushima M

International Journal of Urology   Vol. 17   page： 548-554   2010

Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes

Yamaguchi K, Mandai M, Oura T, Matsumura N, Hamanishi J, Baba T, Matsui S, Murphy SK, Konishi I

Oncogene   Vol. 29   page： 1741-1752   2010

Optimality of gene ranking based on univariate P-values for detecting differentially expressed genes

Noma H, Matsui S

Japanese Journal of Biometrics   Vol. 31   page： 13-21   2010

Sample size calculations for controlling the distribution of false discovery proportion in microarray experiments.

Oura T, Matsui S, Kawakami K

Biostatistics   Vol. 10   page： 694-705   2009

Sample sizes for a robust ranking and selection of genes in microarray experiments.

Matsui S, Oura T

Statistics in Medicine   Vol. 28   page： 2801-2816   2009

Clustering of significant genes in prognostic studies with microarrays: application to a clinical study for multiple myeloma

Matsui S, Yamanaka T, Barlogie B, Shaughnessy J, Crowley J

Statistics in Medicine   Vol. 27   page： 1106-1120   2008

Sample size calculations based on ranking and selection in microarray experiments.

Biometrics   Vol. 64   page： 217-226   2008

Long-term probucol treatment prevents secondary cardiovascular events: a cohort study of patients with heterozygous familial hypercholesterolemia in Japan

Yamashita S, Hbujo H, Arai H, Harada-Shiba M, Matsui S, Fukushima M, Saito Y, Kita T, Matsuzawa Y

Journal of Atherosclerosis Thrombosis   Vol. 15   page： 292-303   2008

Overview of the clinical application of regenerative medicine products in Japan

Tsubouchi M, Matsui S, Banno Y, Kurokawa K, Kawakami K

Health Policy   Vol. 88   page： 62-72   2008

Critical issues for effective collaboration between academia and industry in the field of regenerative medicine in Japan

Tsubouchi M, Morishita R, Tabata Y, Matsui S, Kawakami K

Regenerative Medicine   Vol. 3   page： 497-504   2008

Efficacy, toxicity and cost analysis for non-platinum triplet (gemcitabine and vinorelbine followed by docetaxel) vs. platinum-based chemotherapy in IIIB/IV non-small cell lung cancer: Single institution experience

Tada H, Matsui S, Kawahara M, Hosoe S, Hamada C, Fukushima M

European Journal of Cancer Care   Vol. 17   page： 120-126   2008

Genomic characterization of multiple clinical phenotypes of cancer using multivariate linear regression models.

Matsui S, Ito M, Nishiyama H, Uno H, Kotani H, Watanabe J, Guilford P, Reeve A, Fukushima M, Ogawa O

Bioinformatics   Vol. 23   page： 732-738   2007

P21-activated kinase 1: a new molecular marker for intravesical recurrence after transurethral resection of bladder cancer

Ito M, Nishiyama H, Kawanishi H, Matsui S, Guilford P, Reeve A, Ogawa O

Journal of Urology   Vol. 178   page： 1073-1079   2007

Predicting survival outcomes using subsets of significant genes in prognostic marker studies with microarrays.

Matsui S

BMC Bioinformatics   Vol. 7 ( 156 ) page： 1-9   2006

Reducing false positive findings in statistical analysis of pharmacogenomic biomarker studies using high-throughput technologies

Matsui S

Current Drug Safety2006   Vol. 1   page： 135-141   2006

Lessons from gefitinib-induced interstitial lung disease in Japan and proposal for the prevention of serious drug-induced suffering: Problems in approval, pharmacovigilance, and regulatory decision-making procedures

Nishimura T, Tada H, Nakagawa M, Teramukai S, Matsui S, Fukushima M

Pharmacy Practice   Vol. 4   page： 168-178   2006

Creutzfeldt-Jakob disease and cadaveric dura mater grafts in Japan: an updated analysis of incubation time

Matsui S, Sadaike T, Hamada C, Fukushima M

Neuroepidemiology   Vol. 24   page： 22-25   2005

Sample size calculations for comparative clinical trials with over-dispersed Poisson process data

Matsui S

Statistics in Medicine   Vol. 24   page： 1339-1356   2005

Stratified analysis in randomized trials with noncompliance

Matsui S

Biometrics   Vol. 61   page： 816-823   2005

Erythropoietin as a retinal angiogenic factor

Manzoni P, Maestri A, Gomirato G, Takagi H, Watanabe D, Matsui S

New England Journal of Medicine   Vol. 353   page： 2190-2191   2005

Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy

Watanabe D, Suzuma K, Matsui S, Kurimoto M, Kiryu J, Kita M, Suzuma I, Ohashi H, Ojima T, Murakami T, Kobayashi T, Masuda S, Nagao M, Yoshimura N, Takagi H

New England Journal of Medicine   Vol. 353   page： 782-792   2005

Prognostic factor analysis for plaque psoriasis

Sakai R, Matsui S, Fukushima M, Yasuda H, Miyauchi H, Miyachi Y

Dermatology   Vol. 211   page： 103-106   2005

Analysis of times to repeated events in two-arm randomized trials with noncompliance and early withdrawal Reviewed

Matsui S

Biometrics   Vol. 60   page： 965-976   2004

Functional assessment of self-renewal activity of male germline stem cells following cytotoxic damage and serial transplantation.

Shinohara M, Toyokuni S, Morimoto T, Matsui S, Honjo T, Shinohara T

Biology of Reproduction   Vol. 68   page： 1801-1807   2003

中間解析における頻度論的アプローチ：最近の理論的展開

松井茂之, 宇野一, 小山暢之

計量生物学   Vol. 21   page： 87-124   2000

中間解析におけるベイズ流アプローチ：最近の理論的展開

宇野一, 松井茂之, 小山暢之

計量生物学   Vol. 21   page： 125-149   2000

Analysis of recurrent events: Application to a clinical trial of colony stimulating factor with the endpoint of febrile neutropenia

Matsui S, Ohashi Y

Statistics in Medicine   Vol. 18   page： 2409-2420   1999

Design of clinical trials for recurrent events with periodic monitoring

Matsui S, Miyagishi H

Statistics in Medicine   Vol. 18   page： 3005-3020   1999

Frontiers of Biostatistical Methods and Applications in Clinical Oncology.

Matsui S, Crowley J（ Role： Joint author）

Springer  2017.10 

Design and Analysis of Clinical Trials for Predictive Medicine

Matsui S, Buyse M, Simon R（ Role： Joint author）

CRC   2015.3 

Univariate analysis for gene screening: beyond the multiple testing

Noma H, Matsui S（ Role： Joint author）

CRC  2015.3 

Statistical issues in clinical development and validation of genomic signatures

Matsui S（ Role： Sole author）

CRC  2015.3 

Phase III all-comers clinical trials with a predictive biomarker

Matsui S, Choai Y, Nonaka T（ Role： Joint author）

CRC  2015.3 

Phase I dose-finding designs and their applicability to targeted therapies

Daimon T, Hirakawa A, Matsui S（ Role： Joint author）

CRC  2015.3 

Clinical trials for predictive medicine: new paradigms and challenges. In Design and Analysis of Clinical Trials for Predictive Medicine

Simon R, Matsui S, Buyse M（ Role： Joint author）

CRC  2015.3 

Developments in Statistical Evaluation of Clinical Trials

（ Role： Joint author）

2014 

Developments in Statistical Evaluation of Clinical Trials

Matsui S, Nonaka T, Choai Y（ Role： Joint author）

Springer  2014 

Handbook of Statistics in Clinical Oncology, 3rd edn. (eds JJ. Crowley and A Hoering)

Matsui S, Noma H（ Role： Sole author）

CRC Press  2012 

臨床試験ハンドブック

松井茂之（ Role： Sole author）

朝倉書店  2006 

Handbook of Statistics in Clinical Oncology, 2nd edn. (eds J.J. Crowley and D.P. Ankerst)

Matsui S（ Role： Sole author）

CRC Press  2006 

Blinded Sample Size Re-estimation in Comparative Clinical Trials with Over-Dispersed Count Data: Incorporation of Misspecification of the Variance Function. International conference

Masataka Igeta, Shigeyuki Matsui

Eastern North American Region International Biometric Society, 2019 Meeting 

Multiple Testing and Estimation of Disease Associations Based on Semi-Parametric Hierarchical Mixture Models, Possibly Incorporating Brain Areas International conference

Ryo Emoto, Takahiro Otani, Shigeyuki Matsui

Eastern North American Region International Biometric Society, 2019 Meeting 

生物・医学分野の新たな展開：データを中心とした拡がり/繋がり Invited

松井茂之

2018年度統計関連学会連合大会日本計量生物学会シンポジウム 

単変量Cox回帰にもとづく遺伝子選択と複合共変量による生存期間の予測

江村剛志、 松井 茂之、Hsuan-Yu Chen 

2018年度統計関連学会連合大会 

脳画像を用いた疾患関連解析における効果サイズ推定

江本 遼, 川口 淳, 松井茂之

2018年度統計関連学会連合大会 

Hierarchical Mixture Modeling for Multiple Testing and Effect Size Estimation in Voxel-Level Inference of Neuroimaging Data. International conference

Ryo Emoto, Atsushi Kawaguchi, Hisako Yoshida, Shigeyuki Matsui.

Joint Statistical Meeting 2019 

Bias-Corrected Estimation of Treatment Effects in Biomarker-Based Adaptive Subgroup Analysis: New Approach Based on Randomized Tests with Smooth Rejection Function International conference

Kiichiro Toyoizumi, Shigeyuki Matsui

Joint Statistical Meeting 2019 

A Transfer Learning Method for Multi-Center Prognostic Prediction Analysis. International conference

Kota Matsui, Kenta Kanamori, Wataru Kumagai, Mitsuaki Nishikimi, Shigeyuki Matsui

3rd International Workshop on Biomedical Informatics with Optimization and Machine Learning in conjunction with 27th International Joint Conference on Artificial Intelligence 

Two-Stage Analysis for Selecting Fixed Numbers of Features in Omics Association Studies International conference

XXIX International Biometric Conference 

Phase III Clinical Trial Design for Targeted Therapies with Uncertain Biomarker Evidence: Controversies and Solutions (Keynote). Invited International conference

Matsui S

OHSU Cancer Biostatistics Workshop 

Omics 研究における検証的解析と探索的解析 Invited

佐藤 俊哉,三中 信宏,松井茂之,寒水 孝司

2017 年度統計関連学会連合大会日本計量生物学会シンポジウム 

セミパラメトリック階層混合モデルによる複雑疾患GWASの解析

西野 穣, 高地 雄太, 重水 大智, 加藤 護, 猪狩 勝則, 越智 秀典, 野間 久史, 松井 孝太, 大谷隆浩, 森園 隆, 松井茂之

第27回 日本疫学会学術総会 

セミパラメトリック階層混合モデルによる複雑疾患の遺伝的構造の推定と集団遺伝学的考察

西野 穣, 松井茂之

統計数理研究所公募型共同研究重点テーマ2：次世代への健康科学共通公開研究集会 

Stage III結腸癌におけるDNAコピー数変化と無再発生存期間の関連～ACTS-CC試験のバイオマーカー探索

石川敏昭，植竹宏之，石黒めぐみ，室谷健太，中谷英仁，小武内尚，松井茂之，杉原健

第71回日本消化器外科学会総会 

Cancer Outlier Analysis Based on a Nested Two-Way Clustering International conference

Oura T, Matsui K, Matsui S

XXVIIIth International Biometric Conference 

A comparison of multiple testing methods for effective strategies in genome-wide association studies International conference

Otani T, Noma H, Nishino J, Matsui K, Matsui S

XXVIIIth International Biometric Conference 

予測マーカーと治療の交互作用検定を用いるランダム化臨床試験における治療効果のバイアス補正

豊泉樹一郎, 松井茂之

2015年度統計関連学会連合大会 

ゲノムワイド関連解析データを用いた複雑疾患の階層混合モデル解析

西野穣, 高地雄太, 野間久史, 重水大智, 森園隆, 角田達彦, 松井茂之

2015年度統計関連学会連合大会 

Biomarker-based all-comers phase III trials: design issues and solutions International conference

Matsui S

The first Pacific Rim Cancer Biostatistics Conference 

Bias-corrected estimation of treatment effects in biomarker-based randomized clinical trials International conference

Toyoizumi K, Matsui S

Joint Statistical Meetings 2015 

MSI, 18q LOH, and clinicopathological features in stage II sporadic colon cancers: Biomarker study in a Phase III Study of Postoperative Adjuvant Chemotherapy for Stage II Colon Cancer (SACURA trial) International conference

Ishikawa T, Uetake H, Ishiguro M, Murotani K, Matsui S, Ueno H, Sugihara K, Tomita N, SACURA study group

ACTS-CC study group. CT211 biomarker search using gene expression databases in a phase III, controlled clinical trial of postoperative adjuvant chemotherapy for stage III colon cancer (ACTS-CC): correlation between clinicopathological factors and gene expression level International conference

Uetake H, Ishikawa T, Ishiguro M, Matsui S, Sugihara K, ACTS-CC study group

American Association for Cancer Research Annual Meeting 2015 

MSI, 18qLOH, and clinicopathologicalfeatures in stage II sporadic colon cancers: Biomarker study in a phase III study of postoperative adjuvantchemotherapyfor stage II colon cancer (SACURA trial) International conference

Ishikawa T, Uetake H, Ishiguro M, Murotani K, Matsui S, Ueno H, Sugihara K, Tomita N, SACURA study group

American Association for Cancer Research Annual Meeting 2015 

計量生物学の更なる可能性を求めて

松井茂之

2014 年度日本計量生物学会賞受賞者講演 

Statistical analysis plans in phase III all-comers clinical trials with a predictive biomarker International conference

Matsui S

The XXVII International Biometric Conference 

A new framework of discrimination analysis for high-dimensional data based on estimation of data structure

Grant number：16K12401  2016.4 - 2019.3

Matsui Shigeyuki

多次元データ解析の新しい枠組み：構造推定と判別解析

2016.4 - 2018.3

科学研究費補助金 

Development of statistical methods based on omics data for realizing predictive medicine

Grant number：15H02671  2015.4 - 2019.3

Matsuura Masaaki

先端医療技術の開発における臨床試験の計画と統計解析に関する研究

2014.4 - 2018.3

科学研究費補助金  基盤研究(A)

Statistical methodology for stabilizing of the genome-omics data analysis

Grant number：25280008  2013.4 - 2018.3

Egichi Shinto

医薬統合プログラム

2020

医科学セミナー・医科学実験研究

2020

医学入門

2020

日本統計学会JSS-Springer 編集委員

Role(s)：Planning, management, etc.

2020.1 - 2020.12

日本統計学会 JJSD支援委員

Role(s)：Planning, management, etc.

2020.1 - 2020.12

Japanese Journal of Statistics and Data Science, Coordinating Editor

Role(s)：Planning, management, etc.

2020.1 - 2020.12