Dysregulated Anaerobic Glycolysis in Podocytes is Relevant to the Progression of Focal Segmental Glomerulosclerosis Open Access

Sugimura, M; Maeda, K; Shibata, K; Seko, H; Kozaki, Y; Hirayama, A; Soga, T; Ozeki, T; Sato, Y; Kato, N; Kosugi, T; Kadomatsu, K; Maruyama, S

KIDNEY INTERNATIONAL REPORTS   Vol. 10 ( 9 ) page： 3239 - 3254   2025.9

Atypical hemolytic uremic syndrome treated with anti-C5 antibody agent eculizumab, without genetic complement abnormalities

Sato, Y; Kato, N; Asano, M; Shimizu, H; Tatematsu, Y; Shimamura, Y; Horinouchi, A; Maeda, K; Kato, S; Kosugi, T; Maruyama, S

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 87 ( 3 ) page： 573 - 581   2025.8

Safety and efficacy of retreatment with immune checkpoint inhibitors after severe immune-related adverse events

Mizuno, K; Ito, T; Sawada, T; Kobayashi, T; Iwama, S; Mori, S; Hase, T; Fukami, Y; Furusawa, K; Yura, Y; Morimoto, R; Sajiki, A; Ushida, H; Kato, N; Maruyama, S; Murohara, T; Katsuno, M; Ishii, M; Akiyama, M; Arima, H; Kawashima, H; Ando, Y

ONCOLOGIST   Vol. 30 ( 6 )   2025.6

Ameliorative Effect of an Anti-MicroRNA-21 Oligonucleotide on Animal and Human Models of Cystic Kidney Disease

Noda, Y; Kato, N; Sato, F; Suzuki, Y; Tsubota, S; Kitai, H; Komatsu, S; Tanaka, A; Sato, Y; Maeda, K; Furuhashi, K; Ishimoto, T; Kosugi, T; Yamaguchi, T; Nagao, S; Kamiya, Y; Kadomatsu, K; Asanuma, H; Maruyama, S

KIDNEY360   Vol. 6 ( 6 ) page： 900 - 913   2025.6

MPO-ANCA-positive rapidly progressive glomerulonephritis after COVID-19 vaccination during treatment of plaque psoriasis with bimekizumab Open Access

Sugiura, T; Doke, T; Tanaka, A; Sato, Y; Maeda, K; Furuhashi, K; Kato, N; Kosugi, T; Maruyama, S

CEN CASE REPORTS   Vol. 14 ( 2 ) page： 194 - 199   2025.4

In vivo efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney

Tsuboi, T; Hattori, K; Ishimoto, T; Imai, K; Doke, T; Hagita, J; Ariyoshi, J; Furuhashi, K; Kato, N; Ito, Y; Kamiya, Y; Asanuma, H; Maruyama, S

MOLECULAR THERAPY NUCLEIC ACIDS   Vol. 36 ( 1 ) page： 102387   2025.3

Unexpected Hypotension in a Female Patient with Fabry Disease: Switching from Agalsidase α to β after Long-term ERT Open Access

Sugiura, T; Muto, R; Amano, T; Kamiya, F; Sato, Y; Maeda, K; Saito, S; Katsuno, T; Kato, N; Higashi, M; Numaguchi, A; Matsuda, N; Sugiura, K; Maruyama, S

INTERNAL MEDICINE   Vol. 64 ( 15 ) page： 2369 - 2374   2025

Urinary presepsin is a novel biomarker capable of directly assessing monocyte/macrophage infiltration in kidney diseases

Niwa, S; Tanaka, A; Furuhashi, K; Hattori, K; Onogi, C; Sunohara, K; Owaki, A; Kato, A; Kawazoe, T; Watanabe, Y; Koshi-Ito, E; Kato, N; Kosugi, T; Maruyama, S

SCIENTIFIC REPORTS   Vol. 14 ( 1 ) page： 30088   2024.12

Eculizumab for adult patients with atypical haemolytic-uraemic syndrome: full dataset analysis of Japanese post-marketing surveillance Open Access

Maruyama, S; Ikeda, Y; Kaname, S; Kato, N; Matsumoto, M; Ishikawa, Y; Shimono, A; Miyakawa, Y; Nangaku, M; Shibagaki, Y; Okada, H

JOURNAL OF NEPHROLOGY   Vol. 37 ( 8 ) page： 2181 - 2190   2024.11

Safety and Tolerability of Adipose-Derived Mesenchymal Stem Cell (ADR-001) Therapy for IgA Nephropathy

Tanaka, A; Furuhashi, K; Fujieda, K; Horinouchi, A; Maeda, K; Saito, S; Mimura, T; Saka, Y; Naruse, T; Ishimoto, T; Kato, N; Kosugi, T; Kinoshita, F; Kuwatsuka, Y; Nakai, Y; Maruyama, S

KIDNEY360   Vol. 5 ( 11 ) page： 1692 - 1705   2024.11

Annual trends in atypical haemolytic uremic syndrome management in Japan and factors influencing early diagnosis and treatment: a retrospective study

Tatematsu, Y; Imaizumi, T; Michihata, N; Kato, N; Kumazawa, R; Matsui, H; Fushimi, K; Yasunaga, H; Maruyama, S

SCIENTIFIC REPORTS   Vol. 14 ( 1 ) page： 18265   2024.8

Detecting and exploring kidney-derived extracellular vesicles in plasma

Komatsu, S; Kato, N; Kitai, H; Funahashi, Y; Noda, Y; Tsubota, S; Tanaka, A; Sato, Y; Maeda, K; Saito, S; Furuhashi, K; Ishimoto, T; Kosugi, T; Maruyama, S; Kadomatsu, K

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 28 ( 7 ) page： 617 - 628   2024.7

Association of calciprotein particles with serum phosphorus among patients undergoing conventional and extended-hours haemodialysis

Nishibori, N; Okazaki, M; Miura, Y; Hishida, M; Kurasawa, S; Imaizumi, T; Kato, N; Kosugi, T; Kuro-o, M; Kasuga, H; Kaneda, F; Maruyama, S

CLINICAL KIDNEY JOURNAL   Vol. 17 ( 6 ) page： sfae121   2024.6

Clinical impact of proteinuria and hematuria remission criteria in IgA nephropathy patients defined by the Japanese Society of Nephrology

Yasuda, Y; Kaihan, AB; Kaihan, AN; Tanaka, A; Imaizumi, T; Maeda, K; Kato, N; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   Vol. 39   2024.5

Clinical impact of proteinuria and hematuria remission criteria in IgA nephropathy patients defined by the Japanese Society of Nephrology

Yasuda, Y; Kaihan, AB; Kaihan, AN; Tanaka, A; Imaizumi, T; Maeda, K; Kato, N; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   Vol. 39   page： I736 - I737   2024.5

Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study

Kurasawa, S; Kato, S; Ozeki, T; Akiyama, S; Ishimoto, T; Mizuno, M; Tsuboi, N; Kato, N; Kosugi, T; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 28 ( 5 ) page： 431 - 439   2024.5

Case report: A family of atypical hemolytic uremic syndrome involving a <i>CFH::CFHR1</i> fusion gene and <i>CFHR3-1-4-2</i> gene duplication Open Access

Tasaki, Y; Tsujimoto, H; Yokoyama, T; Sugimoto, N; Kitajima, S; Fujii, H; Hidaka, Y; Kato, N; Maruyama, S; Inoue, N; Wada, T

FRONTIERS IN IMMUNOLOGY   Vol. 15   page： 1360855   2024.3

Clinical characteristics of anti-GBM disease with thrombotic microangiopathy: a case report and literature review Open Access

Nakamura, Y; Kato, N; Tatematsu, Y; Arai, Y; Mori, N; Shibata, K; Yamazaki, M; Yasui, H; Fujiwara, S; Yamakawa, T; Maruyama, S

CEN CASE REPORTS   Vol. 13 ( 1 ) page： 37 - 44   2024.2

Overlapping Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy with Mutation in <i>CFI</i> in a Japanese Patient: A Case Report Open Access

Osawa, K; Yamamoto, S; Yamano, Y; Kita, A; Okamoto, K; Kato, N; Tatematsu, Y; Kojima, F; Ohya, M; Hara, S; Murata, SI; Inoue, N; Maruyama, S; Araki, SI

INTERNAL MEDICINE   Vol. 63 ( 12 ) page： 1777 - 1782   2024

Basigin is released in extracellular vesicles derived from the renal tubular epithelium in response to albuminuria Open Access

Watanabe, T; Maeda, K; Kato, N; Seko, H; Sugimura, M; Sato, Y; Ryuge, A; Kato, S; Kadomatsu, K; Maruyama, S; Kosugi, T

NEPHROLOGY   Vol. 28 ( 11 ) page： 629 - 638   2023.11

IgA-dominant glomerulonephritis with DNAJB9-negative fibrillar polytypic immunoglobulin deposits in the subepithelium Open Access

Muto, R; Maeda, K; Fukui, S; Saito, S; Kato, N; Kosugi, T; Shimizu, A; Maruyama, S

CEN CASE REPORTS   Vol. 12 ( 3 ) page： 323 - 328   2023.8

Relapse of atypical hemolytic uremic syndrome triggered by COVID-19: a lesson for the clinical nephrologist Open Access

Uwatoko, R; Shindo, M; Hashimoto, N; Iio, R; Ueda, Y; Tatematsu, Y; Kato, N; Maruyama, S; Hayashi, T

JOURNAL OF NEPHROLOGY   Vol. 36 ( 5 ) page： 1439 - 1442   2023.6

Application of a scoring system in Japanese patients diagnosed with atypical hemolytic uremic syndrome to assess the relationship between the score and clinical responses to eculizumab Open Access

Wada, H; Teranishi, H; Shimono, A; Kato, N; Maruyama, S; Matsumoto, M

THROMBOSIS JOURNAL   Vol. 21 ( 1 ) page： 43   2023.4

Efficacy of On-line Hemodiafiltration for Rhabdomyolysis Presenting with Acute Kidney Injury Due to Unexpected Drug Abuse Open Access

Sato, N; Inagaki, K; Takanashi, M; Muto, R; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   Vol. 62 ( 19 ) page： 2865 - 2870   2023

Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis Open Access

Kitai, H; Kato, N; Ogami, K; Komatsu, S; Watanabe, Y; Yoshino, S; Koshi, E; Tsubota, S; Funahashi, Y; Maeda, T; Furuhashi, K; Ishimoto, T; Kosugi, T; Maruyama, S; Kadomatsu, K; Suzuki, H

BMC BIOLOGY   Vol. 20 ( 1 ) page： 248   2022.11

Abnormal foreshortening of a Flow Re-Direction Endoluminal Device caused by in-stent thrombosis immediately after deployment br Open Access

Otsuka, T; Izumi, T; Nishihori, M; Tsukada, T; Goto, S; Ikezawa, M; Kato, N; Nakano, M; Uda, K; Yokoyama, K; Araki, Y; Saito, R

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 4 ) page： 884 - 889   2022.11

Adrenomedullin for biologic-resistant Crohn's disease: A randomized, double-blind, placebo-controlled phase 2a clinical trial Open Access

Kita, T; Ashizuka, S; Takeda, T; Matsumoto, T; Ohmiya, N; Nakase, H; Motoya, S; Ohi, H; Mitsuyama, K; Hisamatsu, T; Kanmura, S; Kato, N; Ishihara, S; Nakamura, M; Moriyama, T; Saruta, M; Nozaki, R; Yamamoto, S; Inatsu, H; Watanabe, K; Kitamura, K

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 37 ( 11 ) page： 2051 - 2059   2022.11

ECULIZUMAB FOR ADULT PATIENTS WITH ATYPICAL HAEMOLYTIC-UREMIC SYNDROME: FULL DATASET ANALYSIS OF POST-MARKETING SURVEILLANCE IN JAPAN

Maruyama, S; Ikeda, Y; Kaname, S; Kato, N; Matsumoto, M; Ishikawa, Y; Shimono, A; Miyakawa, Y; Nangaku, M; Shibagaki, Y; Okada, H

NEPHROLOGY DIALYSIS TRANSPLANTATION   Vol. 37   page： I231 - I232   2022.5

A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts Open Access

Minatoguchi, S; Saito, S; Furuhashi, K; Sawa, Y; Okazaki, M; Shimamura, Y; Kaihan, AB; Hashimoto, Y; Yasuda, Y; Hara, A; Mizutani, Y; Ando, R; Kato, N; Ishimoto, T; Tsuboi, N; Esaki, N; Matsuyama, M; Shiraki, Y; Kobayashi, H; Asai, N; Enomoto, A; Maruyama, S

SCIENTIFIC REPORTS   Vol. 12 ( 1 ) page： 5389   2022.3

The 30-year Natural History of Non-classic Fabry Disease with an R112H Mutation Open Access

Muto, R; Inagaki, K; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   Vol. 61 ( 11 ) page： 1727 - 1730   2022

X-chromosome inactivation patterns in females with Fabry disease examined by both ultra-deep RNA sequencing and methylation-dependent assay Open Access

Rossanti, R; Nozu, K; Fukunaga, A; Nagano, C; Horinouchi, T; Yamamura, T; Sakakibara, N; Minamikawa, S; Ishiko, S; Aoto, Y; Okada, E; Ninchoji, T; Kato, N; Maruyama, S; Kono, K; Nishi, S; Iijima, K; Fujii, H

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 25 ( 11 ) page： 1224 - 1230   2021.11

Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis Open Access

Ryuge, A; Kosugi, T; Maeda, K; Banno, R; Gou, Y; Zaitsu, K; Ito, T; Sato, Y; Hirayama, A; Tsubota, S; Honda, T; Nakajima, K; Ozaki, T; Kondoh, K; Takahashi, K; Kato, N; Ishimoto, T; Soga, T; Nakagawa, T; Koike, T; Arima, H; Yuzawa, Y; Minokoshi, Y; Maruyama, S; Kadomatsu, K

JCI INSIGHT   Vol. 6 ( 20 )   2021.10

A Case of TAFRO Syndrome with Two Consecutive Renal Biopsies Following the Pathological Course of the Kidney

Kato, N; Hasegawa, T; Muto, R; Tanaka, A; Sato, Y; Maeda, K; Furuhashi, K; Saito, S; Kosugi, T; Maruyama, S

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY   Vol. 32 ( 10 ) page： 823 - 824   2021.10

Eculizumab for Treatment of Recurrent Pregnancy-Triggered Atypical Hemolytic-Uremic Syndrome with a Mutation in Complement 3: A Case Report

Miyabe, Y; Nakai, A; Watanabe, K; Karasawa, K; Kato, N; Maruyama, S; Moriyama, T; Nitta, K

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY   Vol. 32 ( 10 ) page： 826 - 827   2021.10

The ISN/RPS 2016 classification predicts renal prognosis in patients with first-onset class III/IV lupus nephritis Open Access

Hachiya, A; Karasawa, M; Imaizumi, T; Kato, N; Katsuno, T; Ishimoto, T; Kosugi, T; Tsuboi, N; Maruyama, S

SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page： 1525   2021.1

Acquired Fanconi Syndrome in a Patient with Nontyphoidal <i>Salmonella</i> Bacteremia Open Access

Ryuge, A; Saito, S; Morioka, H; Hachiya, A; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S

INTERNAL MEDICINE   Vol. 60 ( 5 ) page： 761 - 764   2021

Refractory Hypotension Caused by Selenium Deficiency in a Patient on Peritoneal Dialysis Open Access

Ryuge, A; Kim, H; Suzuki, Y; Okazaki, M; Kojima, H; Saito, S; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S; Mizuno, M

INTERNAL MEDICINE   Vol. 60 ( 15 ) page： 2461 - 2464   2021

THE ROLE OF FRUCTOSE METABOLISM IN VASCULAR ENDOTHELIAL FUNCTION IN DIABETES

Ishimoto, T; Doke, T; Hayasaki, T; Kato, N; Maruyama, S

NEPHROLOGY   Vol. 25   page： 62 - 62   2020.10

EXOSOMES FROM CKD PATIENTS HAVE ATHEROSCLEROGENIC PROPERTIES

Kato, N; Nishio, F; Ishimoto, T; Kosugi, T; Maruyama, S

NEPHROLOGY   Vol. 25   page： 62 - 62   2020.10

Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Open Access

Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL Jr, Putluri N, Zeisberg M, Zeisberg EM, LeBleu VS, Kalluri R

Science signaling   Vol. 13 ( 635 )   2020.6

Ectopic Relapse of Anti-neutrophil Cytoplasmic Antibody-associated Pituitary Vasculitis with No Elevation of Anti-neutrophil Cytoplasmic Antibodies after Renal Remission Open Access

Muto, R; Inagaki, K; Sato, N; Sameshima, T; Nagakura, Y; Baba, S; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   Vol. 59 ( 24 ) page： 3187 - 3193   2020

Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase Open Access

Hayasaki, T; Ishimoto, T; Doke, T; Hirayama, A; Soga, T; Furuhashi, K; Kato, N; Kosugi, T; Tsuboi, N; Lanaspa, MA; Johnson, RJ; Maruyama, S; Kadomatsu, K

JOURNAL OF NUTRITIONAL BIOCHEMISTRY   Vol. 71   page： 54 - 62   2019.9

miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury Open Access

Funahashi, Y; Kato, N; Masuda, T; Nishio, F; Kitai, H; Ishimoto, T; Kosugi, T; Tsuboi, N; Matsuda, N; Maruyama, S; Kadomatsu, K

LABORATORY INVESTIGATION   Vol. 99 ( 8 ) page： 1130 - 1142   2019.8

CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling Open Access

Yoshioka, T; Kosugi, T; Masuda, T; Watanabe, T; Ryuge, A; Nagaya, H; Maeda, K; Sato, Y; Katsuno, T; Kato, N; Ishimoto, T; Yuzawa, Y; Maruyama, S; Kadomatsu, K

AMERICAN JOURNAL OF PATHOLOGY   Vol. 189 ( 7 ) page： 1338 - 1350   2019.7

NOVEL PATHOPHYSIOLOGIC ROLE OF MIR-146A FOR SPLENIC MACROPHAGE INTERFERENCE IN SEPSIS-RELATED KIDNEY INJURY

Funahashi, Y; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   Vol. 34   2019.6

Therapeutic efficacy of rituximab for the management of adult-onset steroid-dependent nephrotic syndrome: a retrospective study. Open Access

Katsuno T, Masuda T, Saito S, Kato N, Ishimoto T, Kato S, Kosugi T, Tsuboi N, Kitamura H, Tsuzuki T, Ito Y, Maruyama S

Clinical and experimental nephrology   Vol. 23 ( 2 ) page： 207 - 214   2019.2

Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018 Open Access

Okada Hirokazu, Yasuda Yoshinari, Kashihara Naoki, Asahi Koichi, Ito Takafumi, Kaname Shinya, Kanda Eiichiro, Kanno Yoshihiko, Shikata Kenichi, Shibagaki Yugo, Tsuchiya Ken, Tsuruya Kazuhiko, Nagata Daisuke, Narita Ichiei, Nangaku Masaomi, Hattori Motoshi, Hamano Takayuki, Fujimoto Shouichi, Moriyama Toshiki, Yamagata Kunihiro, Yamamoto Ryohei, Wakasugi Minako, Ashida Akira, Usui Joichi, Kawamura Kazuko, Kitamura Kenichiro, Konta Tsuneo, Suzuki Yusuke, Tsuruoka Shuichi, Nishio Saori, Hamano Takayuki, Fujii Naohiko, Fujii Hideki, Wada Takehiko, Yokoyama Hitoshi, Aoki Katsunori, Akiyama Daiichiro, Araki Shin-ichi, Arima Hisatomi, Ishikawa Eiji, Ishikura Kenji, Ishizuka Kiyonobu, Ishimoto Takuji, Ishimoto Yu, Iseki Kunitoshi, Itabashi Mitsuyo, Ichioka Satoko, Ichikawa Kazunobu, Ichikawa Daisuke, Inoue Shuji, Imai Toshimi, Imamura Hideaki, Iwata Yasunori, Iwazu Yoshitaka, Usui Toshiaki, Uchida Keiko, Egawa Masahiro, Ohara Shinichiro, Omori Norio, Okada Rieko, Okuda Yusuke, Ozeki Takaya, Obata Yoko, Kai Hirayasu, Kato Noritoshi, Kanasaki Keizo, Kaneko Yoshikatsu, Kabasawa Hideyuki, Kawaguchi Takehiko, Kawasaki Yukihiko, Kawashima Keisuke, Kawano Haruna, Kikuchi Kan, Kihara Masao, Kimura Yoshiki, Kurita Noriaki, Koike Kentaro, Koizumi Masahiro, Kojima Chiari, Goto Shunsuke, Konomoto Takao, Kohagura Kentaro, Komatsu Hiroyuki, Komaba Hirotaka, Saito Chie, Sakai Yukinao, Sakaguchi Yusuke, Satonaka Hiroshi, Jimi Kanako, Shimizu Akihiro, Shimizu Sayaka, Shirai Sayuri, Shinzawa Maki, Sugiyama Kazuhiro, Suzuki Tomo, Suzuki Hitoshi, Suyama Kazuhide, Segawa Hiroyoshi, Takahashi Kazuya, Tanaka Kenichi, Tanaka Tetsuhiro, Tsunoda Ryoya, Tsuruta Yuki, Nakakura Hyogo, Nagasawa Yasuyuki, Nakanishi Koichi, Nagahama Masahiko, Nakaya Izaya, Nanami Masayoshi, Niihata Kakuya, Nishi Shinichi, Nishiwaki Hiroki, Hasegawa Shoko, Hasegawa Midori, Hanada Ken, Hayashi Hiroki, Harada Ryoko, Hishida Manabu, Hirano Daishi, Hirahashi Junichi, Hirama Akio, Hirayama Kouichi, Fukagawa Masafumi, Fukuda Akihiro, Fujii Yoshiyuki, Fujisaki Kiichiro, Furuya Fumihiko, Hoshino Junichi, Hosojima Michihiro, Honda Kenjiro, Masuda Takahiro, Matsui Kosuke, Matsukuma Yuta, Matsumura Hideki, Mii Akiko, Miura Kenichiro, Mitobe Michihiro, Miyasato Yoshikazu, Miyamoto Satoshi, Miwa Saori, Yazawa Masahiko, Yata Yusuke, Yamamoto Yoshihiro, Watanabe Kimio, Hosojima Michihiro

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 23 ( 1 ) page： 1-15   2019.1

Investigation on the benefits of mycophenolate mofetil and therapeutic drug monitoring in the treatment of Japanese patients with lupus nephritis. Open Access

Katsuno T, Ozaki T, Ozeki T, Hachiya A, Kim H, Kato N, Ishimoto T, Kato S, Kosugi T, Tsuboi N, Mizuno M, Ito Y, Maruyama S

Clinical and experimental nephrology   Vol. 22 ( 6 ) page： 1341 - 1350   2018.12

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice. Open Access

Doke T, Ishimoto T, Hayasaki T, Ikeda S, Hasebe M, Hirayama A, Soga T, Kato N, Kosugi T, Tsuboi N, Lanaspa MA, Johnson RJ, Kadomatsu K, Maruyama S

Metabolism: clinical and experimental   Vol. 85   page： 161 - 170   2018.8

The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases Open Access

Mori Yoshiko, Masuda Tomohiro, Kosugi Tomoki, Yoshioka Tomoki, Hori Mayuko, Nagaya Hiroshi, Maeda Kayaho, Sato Yuka, Kojima Hiroshi, Kato Noritoshi, Ishimoto Takuji, Katsuno Takayuki, Yuzawa Yukio, Kadomatsu Kenji, Maruyama Shoichi

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 22 ( 4 ) page： 815 - 824   2018.8

MIR-146A TARGETING SPLENIC MACROPHAGES PREVENTS SEPSIS-INDUCED MULTIPLE ORGAN INJURY INCLUDING ACUTE KIDNEY INJURY

Funahashi Yoshio, Kato Noritoshi, Kitai Hiroki, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Matsuda Naoyuki, Maruyama Shoichi, Kadomatsu Kenji

SHOCK   Vol. 49 ( 6 ) page： 21 - 21   2018.6

THE DURATION FROM THE RECOGNITION OF SHOCK TO THE INITIATION OF PMX-DHP IS A CRITICAL DETERMINANT OF SURVIVAL IN PATIENTS WITH SEPTIC SHOCK

Funahashi Yoshio, Kato Noritoshi, Ozeki Takaya, Kobayashi Azusa, Oishi Hideto, Maruyama Shoichi

SHOCK   Vol. 49 ( 6 ) page： 68 - 68   2018.6

INDUCTION OF IMMUNOSUPPRESSIVE MICRO-RNA IN SPLEEN ATTENUATES SEPSIS INDUCED ACUTE KIDNEY INJURY

Funahashi, Y; Kato, N; Ishimoto, T; Kosugi, T; Tsuboi, N; Kadomatsu, K; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   Vol. 32   2017.5

Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis Open Access

Masuda Tomohiro, Maeda Kayaho, Sato Waichi, Kosugi Tomoki, Sato Yuka, Kojima Hiroshi, Kato Noritoshi, Ishimoto Takuji, Tsuboi Naotake, Uchimura Kenji, Yuzawa Yukio, Maruyama Shoichi, Kadomatsu Kenji

AMERICAN JOURNAL OF PATHOLOGY   Vol. 187 ( 4 ) page： 740 - 751   2017.4

A CASE OF RAPIDLY PROGRESSIVE NEPHRITIC SYNDROME AND NEPHROTIC SYNDROME DURING THE TREATMENT OF DERMATOMYOSITIS AND DIABETES

Sato Naokazu, Katsuno Takayuki, Mori Masayoshi, Saito Shouji, Kato Noritoshi, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Ito Yasuhiko, Maruyama Shouichi

RHEUMATOLOGY   Vol. 56   page： 75 - 75   2017.3

Single-dose Rituximab Therapy for Refractory Idiopathic Membranous Nephropathy: A Single-center Experience Open Access

Katsuno Takayuki, Ozaki Takenori, Kim Hangsoo, Kato Noritoshi, Suzuki Yasuhiro, Akiyama Shinichi, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Ito Yasuhiko, Maruyama Shoichi

INTERNAL MEDICINE   Vol. 56 ( 13 ) page： 1679 - 1686   2017

Increase of Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody (ANCA) in Patients with Renal ANCA-associated Vasculitis: Association with Risk to Relapse. Reviewed Open Access

J Rheumatol.     page： 1853-60   2015.9

CD147/basigin limits lupus nephritis and Th17 cell differentiation in mice by inhibiting the interleukin-6/STAT-3 pathway. Reviewed

Maeda K, Kosugi T, Sato W, Kojima H, Sato Y, Kamimura D, Kato N, Tsuboi N, Yuzawa Y, Matsuo S, Murakami M, Maruyama S, Kadomatsu K.

Arthritis Rheumatol.     page： 2185-95   2015.5

The efficacy of tolvaptan as a diuretic for chronic kidney disease patients. Reviewed

Tanaka A, Katsuno T, Ozaki T, Sakata F, Kato N, Suzuki Y, Kosugi T, Kato S, Tsuboi N, Sato W, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

Acta Cardiol.     page： 217-23.   2015.4

Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Reviewed Open Access

Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R

Cancer Cell     page： 707-21   2014.11

CD147/basigin reflects renal dysfunction in patients with acute kidney injury. Reviewed

Nagaya H, Kosugi T, Maeda-Hori M, Maeda K, Sato Y, Kojima H, Hayashi H, Kato N, Ishimoto T, Sato W, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S.

Clin Exp Nephrol.     page： 746-54   2014.10

TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. Reviewed Open Access

Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH 2nd, LeBleu VS, Kalluri R.

J Am Soc Nephrol.     page： 385-92.   2013.2

Deficiency of growth factor midkine exacerbates necrotizing glomerular injuries in progressive glomerulonephritis. Reviewed Open Access

Kojima H, Kosugi T, Sato W, Sato Y, Maeda K, Kato N, Kato K, Inaba S, Ishimoto T, Tsuboi N, Matsuo S, Maruyama S, Yuzawa Y, Kadomatsu K.

Am J Pathol.     page： 410-9   2013.2

Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Reviewed Open Access

Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K.

Am J Pathol.     page： 572-9.   2011.2

The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion. Reviewed Open Access

Kato N, Yuzawa Y, Kosugi T, Hobo A, Sato W, Miwa Y, Sakamoto K, Matsuo S, Kadomatsu K.

J Am Soc Nephrol.     page： 1565-76   2009.7

The growth factor midkine regulates the renin-angiotensin system in mice. Reviewed Open Access

Hobo A, Yuzawa Y, Kosugi T, Kato N, Asai N, Sato W, Maruyama S, Ito Y, Kobori H, Ikematsu S, Nishiyama A, Matsuo S, Kadomatsu K.

J Clin Invest.     page： 1616-25   2009.6

Overexpression of calmodulin in pancreatic beta cells induces diabetic nephropathy. Reviewed Open Access

Yuzawa Y, Niki I, Kosugi T, Maruyama S, Yoshida F, Takeda M, Tagawa Y, Kaneko Y, Kimura T, Kato N, Yamamoto J, Sato W, Nakagawa T, Matsuo S.

J Am Soc Nephrol.     page： 1701-11   2008.9

Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy. Reviewed

Kosugi T, Yuzawa Y, Sato W, Arata-Kawai H, Suzuki N, Kato N, Matsuo S, Kadomatsu K.

Lab Invest.     page： 903-13   2007.9

Renal plasma flow (RPF) and accurate GFR equations utilizing metabolomics analysis

Grant number：20H03575  2020.4 - 2023.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

Yasuda Yoshinari

Usefulness of Basigin as a novel therapeutic target for diabetic kidney and liver diseases

Grant number：20K08632  2020.4 - 2023.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

KOSUGI TOMOKI

Development of a treatment for septic AKI using microRNAs and adipose stem cell-derived exosomes.

Grant number：19K08676  2019.4 - 2022.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

Noritoshi Kato

Novel CaMK4-mediated podocyte-specific therapy in refractory renal disease

Grant number：19K08723  2019.4 - 2022.3

Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

Maeda Kayaho

The development of nucleic acid therapeutic against sepsis targeting splenic macrophage

Grant number：18K19562  2018.6 - 2020.3

Grant-in-Aid for Challenging Research (Exploratory)

Yasuda Yoshinari

Investigation of safer methods of therapeutic miRNA and exosomes

Grant number：16K09610  2016.4 - 2019.3

Kato Noritoshi

心腎連関における細胞外小胞Exosomesの役割と、心予後予測因子の開発

2014.4 - 2016.3

科学研究費補助金  若手研究(B)