Updated on 2021/03/17

写真a

 
KANDA Mitsuro
 
Organization
Graduate School of Medicine Program in Integrated Medicine Musculoskeletal and Cutaneous Medicine Lecturer
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Lecturer
Contact information
メールアドレス

Degree 1

  1. 博士(医学) ( 2010.3   名古屋大学 ) 

Research Interests 4

  1. Surgical oncology

  2. Translational research

  3. Gastric cancer

  4. Esophageal cancer

Research Areas 1

  1. Life Science / Digestive surgery

Current Research Project and SDGs 1

  1. 消化器癌を対象としたトランスレーショナルリサーチ

Research History 4

  1. Nagoya University   Graduate School of Medicine Program in Integrated Medicine Musculoskeletal and Cutaneous Medicine   Lecturer

    2019.5

  2. 名古屋大学医学部附属病院 助教

    2013.4 - 2019.4

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    Country:Japan

  3. 名古屋大学医学部附属病院 病院助教

    2012.9 - 2013.3

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    Country:Japan

  4. Johns Hopkins University, postdoctoral fellow

    2010.9 - 2012.8

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    Country:United States

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    2007.4 - 2010.3

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    Country: Japan

  2. Nagoya University   Faculty of Medicine

    - 2001.3

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    Country: Japan

Professional Memberships 18

  1. 日本外科学会

  2. 日本消化器外科学会

  3. 日本肝臓学会

  4. 日本消化器病学会

  5. 日本胃癌学会

  6. 日本膵臓学会

  7. 日本内視鏡外科学会

  8. 日本癌学会

  9. 日本癌治療学会

  10. 日本消化器癌発生学会

  11. 日本臨床外科学会

  12. American Association for Cancer Research

  13. American Society of Clinical Oncology

  14. American Pancreatic Association

  15. International Association of Pancreatology

  16. European Society of Medical Oncology

  17. Asian-Pacific Hepato-Pancreatro-Biliary Association

  18. 日本食道学会

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Committee Memberships 1

  1. 日本胃癌学会   会誌編集委員会  

       

Awards 5

  1. 日本胃癌学会 優秀研究賞

    2017.3  

  2. 日本医師会 医学研究奨励賞

    2016.7  

  3. JSS Young Researcher Award

    2014.4  

  4. JSGS Young Investigator of the Year 2013

    2013.7  

  5. AACR Scholar-in-training Award

    2009.4  

 

Papers 263

  1. Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway Reviewed

    Miwa Takashi, Kanda Mitsuro, Shimizu Dai, Umeda Shinichi, Sawaki Koichi, Tanaka Haruyoshi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER     2021.2

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41416-021-01271-7

    Web of Science

  2. Development of novel combination cancer immunotherapy using anti-PD-1 and anti-PD-L1 antibody Reviewed

    Hasegawa Hirotaka, Sugiyama Daisuke, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Nomoto Shuji, Fujiwara Michitaka, Kodera Yasuhiro, Nishikawa Hiroyoshi

    CANCER SCIENCE   Vol. 112   page: 741 - 741   2021.2

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    Publishing type:Research paper (scientific journal)  

    Web of Science

  3. STRA6 expression serves as a prognostic biomarker of gastric cancer Reviewed

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 780 - 780   2021.2

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    Publishing type:Research paper (scientific journal)  

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  4. Function and prognostic value of melanoma-associated antigen-D4 protein in esophageal squamous cell carcinoma Reviewed

    Sawaki Koichi, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Uno Yasuo, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 112   page: 531 - 531   2021.2

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    Publishing type:Research paper (scientific journal)  

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  5. Age-Related Differences in the Prognosis of Pancreatic Cancer According to Perioperative Systemic Therapy Reviewed

    Sonohara Fuminori, Yamada Suguru, Kurimoto Keisuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 50 ( 1 ) page: 37 - 46   2021.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0000000000001712

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  6. Pancreatic Fat and Body Composition Measurements by Computed Tomography are Associated with Pancreatic Fistula After Pancreatectomy Reviewed

    Tanaka Katsuhito, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 1 ) page: 530 - 538   2021.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-08581-9

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  7. Newly developed primary malignancies in long-term survivors who underwent curative esophagectomy for squamous cell carcinoma of the esophagus Reviewed

    Shimizu Dai, Koike Masahiko, Kanda Mitsuro, Sonohara Fuminori, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Kodera Yasuhiro

    SURGERY TODAY   Vol. 51 ( 1 ) page: 153 - 158   2021.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-020-02072-w

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  8. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue Reviewed

    Nakagawa Nobuhiko, Tanaka Katsuhito, Sonohara Fuminori, Kandimalla Raju, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6665 - 6676   2020.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.14690

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  9. miR-23b-3p Plays an Oncogenic Role in Hepatocellular Carcinoma Reviewed

    Hayashi Masamichi, Yamada Suguru, Kurimoto Keisuke, Tanabe Hiroshi, Hirabayashi Sho, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY     2020.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-09283-y

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  10. MZB1 expression indicates poor prognosis in estrogen receptor-positive breast cancer Reviewed

    Watanabe Manabu, Shibata Masahiro, Inaishi Takahiro, Ichikawa Takahiro, Soeda Ikumi, Miyajima Noriyuki, Takano Yuko, Takeuchi Dai, Tsunoda Nobuyuki, Kanda Mitsuro, Kikumori Toyone, Kodera Yasuhiro, Nagino Masato

    ONCOLOGY LETTERS   Vol. 20 ( 5 )   2020.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3892/ol.2020.12059

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  11. Characteristics Associated with Nodal and Distant Recurrence after Curative Resection of Squamous Cell Carcinoma of the Thoracic Esophagus Reviewed

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Hayashi Masamichi, Hattori Norifumi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   Vol. 231 ( 4 ) page: E121 - E121   2020.10

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    Publishing type:Research paper (scientific journal)  

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  12. ASO Author Reflections: Characteristics Associated with Nodal and Distant Recurrence After Radical Esophagectomy for Squamous Cell Carcinoma of the Thoracic Esophagus Reviewed

    Kanda Mitsuro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 9 ) page: 3206 - 3207   2020.9

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-08413-w

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  13. ASO Author Reflections: Expression and Malignant Potential of B4GALNT4 in Esophageal Squamous Cell Carcinoma Reviewed

    Baba Hayato, Kanda Mitsuro, Kodera Yasuhiro, Fujii Tsutomu

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 9 ) page: 3257 - 3258   2020.9

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-08458-x

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  14. Therapeutic monoclonal antibody targeting of neuronal pentraxin receptor to control metastasis in gastric cancer Reviewed

    Kanda Mitsuro, Shimizu Dai, Sawaki Koichi, Nakamura Shunsuke, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Hayashi Masamichi, Iguchi Yohei, Yamada Suguru, Katsuno Masahisa, Kodera Yasuhiro

    MOLECULAR CANCER   Vol. 19 ( 1 )   2020.8

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12943-020-01251-0

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  15. The impact of cancer stem cell markers in the tissues of pancreatic ductal adenocarcinoma for prognosis after surgical resections Reviewed

    Inokawa Yoshikuni, Yamada Suguru, Hayashi Masamichi, Sunagawa Yuki, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 80 ( 16 )   2020.8

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1158/1538-7445.AM2020-6016

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  16. ASO Author Reflections: KCNJ15 Expression and Malignant Behavior of Esophageal Squamous Cell Carcinoma Reviewed

    Nakamura Shunsuke, Kanda Mitsuro, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 7 ) page: 2569 - 2570   2020.7

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-020-08337-5

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  17. High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences Reviewed

    Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL     2020.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/01635581.2020.1779758

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  18. Novel Prognostic Implications of DUPAN-2 in the Era of Initial Systemic Therapy for Pancreatic Cancer Reviewed

    Sunagawa Yuki, Yamada Suguru, Sato Yusuke, Morimoto Daishi, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2081 - 2089   2020.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-019-07981-w

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  19. PRAME as a Potential Biomarker for Liver Metastasis of Gastric Cancer Reviewed

    Baba Hayato, Kanda Mitsuro, Sawaki Koichi, Umeda Shinichi, Miwa Takashi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Kodera Yasuhiro, Fujii Tsutomu

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2071 - 2080   2020.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-019-07985-6

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  20. Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer Reviewed

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CANCER   Vol. 146 ( 10 ) page: 2865 - 2876   2020.5

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ijc.32705

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  21. Exploration of Exosomal Micro RNA Biomarkers Related to Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Reviewed

    Sonohara Fuminori, Yamada Suguru, Takeda Shigeomi, Hayashi Masamichi, Suenaga Masaya, Sunagawa Yuki, Tashiro Mitsuru, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 1843 - 1853   2020.4

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.14138

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  22. Detection of indocyanine green fluorescence to determine tumor location during laparoscopic gastrectomy for gastric cancer: Results of a prospective study Reviewed

    Tanaka Chie, Kanda Mitsuro, Funasaka Kohei, Miyahara Ryoji, Murotani Kenta, Tanaka Yuri, Takeda Shigeomi, Kobayashi Daisuke, Hirooka Yoshiki, Fujiwara Michitaka, Goto Hidemi, Kodera Yasuhiro

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY   Vol. 13 ( 2 ) page: 160 - 167   2020.4

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/ases.12710

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  23. Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study Reviewed

    Okada Norio, Iwama Shintaro, Okuji Takayuki, Kobayashi Tomoko, Yasuda Yoshinori, Wada Eri, Onoue Takeshi, Goto Motomitsu, Sugiyama Mariko, Tsunekawa Taku, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Kanda Mitsuro, Yokota Kenji, Hashimoto Naozumi, Ando Masahiko, Fujimoto Yasushi, Nagino Masato, Kodera Yasuhiro, Fujishiro Mitsuhiro, Hibi Hideharu, Sone Michihiko, Kiyoi Hitoshi, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

    BRITISH JOURNAL OF CANCER   Vol. 122 ( 6 ) page: 771 - 777   2020.3

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41416-020-0736-7

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  24. Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer Reviewed

    Nakagawa Nobuhiko, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 3 ) page: 887 - 895   2020.3

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-019-08047-7

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  25. Preoperative predictors of postoperative complications after gastric cancer resection (vol 50, pg 3, 2020) Reviewed

    Kanda Mitsuro

    SURGERY TODAY   Vol. 50 ( 3 ) page: 321 - 321   2020.3

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-019-01948-w

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  26. Predictive value of the modified systemic inflammation score in patients undergoing curative resection of squamous cell carcinoma of the esophagus Reviewed

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 )   2020.2

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  27. A prospective trial to evaluate treatment effects of a beta-hydroxy-beta-methylbutyrate containing nutrient for leakage a the anastomotic site after esophagectomy Reviewed

    Kanda Mitsuro, Koike Masahiko, Fukaya Masahide, Miyata Kazushi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Murotani Kenta, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page: 33 - 37   2020.2

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.82.1.33

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  28. Preoperative six-minute walk distance as a predictor of postoperative complication in patients with esophageal cancer Reviewed

    Inoue Takayuki, Ito Satoru, Kanda Mitsuro, Niwa Yukiko, Nagaya Motoki, Nishida Yoshihiro, Hasegawa Yoshinori, Koike Masahiko, Kodera Yasuhiro

    DISEASES OF THE ESOPHAGUS   Vol. 33 ( 2 )   2020.2

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/dote/doz050

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  29. Preoperative predictors of postoperative complications after gastric cancer resection Reviewed

    Kanda Mitsuro

    SURGERY TODAY   Vol. 50 ( 1 ) page: 3 - 11   2020.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00595-019-01877-8

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  30. The Significance of Molecular Biomarkers on Clinical Survival Outcome Differs Depending on Colon Cancer Sidedness Reviewed

    Hirabayashi Sho, Hayashi Masamichi, Nakayama Goro, Mii Shinji, Hattori Norifumi, Tanabe Hiroshi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Takahashi Masahide, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 40 ( 1 ) page: 201 - 211   2020.1

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.13941

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  31. Characteristics of Lung Metastasis as an Initial Recurrence Pattern After Curative Resection of Pancreatic Cancer Reviewed

    Morimoto Daishi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 49 ( 5 ) page: 699 - 705   2020

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0000000000001559

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  32. ASO Author Reflections: Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival Reviewed

    Miwa Takashi, Kanda Mitsuro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26   page: S596 - S597   2019.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-019-07405-9

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  33. ASO Author Reflections: Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer Reviewed

    Uno Yasuo, Kanda Mitsuro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26   page: S592 - S593   2019.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-019-07404-w

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  34. Comparison of non-invasive liver reserve and fibrosis models: Implications for surgery and prognosis for hepatocellular carcinoma Reviewed

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Tashiro Mitsuru, Sunagawa Yuki, Morimoto Daishi, Tanaka Haruyoshi, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HEPATOLOGY RESEARCH   Vol. 49 ( 11 ) page: 1305 - 1315   2019.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/hepr.13400

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  35. The levels of SYT13 and CEA mRNAs in peritoneal lavages predict the peritoneal recurrence of gastric cancer Reviewed

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 22 ( 6 ) page: 1143 - 1152   2019.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10120-019-00967-3

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  36. PRAME Expression as a Potential Biomarker for Hematogenous Recurrence of Esophageal Squamous Cell Carcinoma Reviewed

    Baba Hayato, Kanda Mitsuro, Sawaki Koichi, Shimizu Dai, Umeda Shinichi, Koike Masahiko, Kodera Yasuhiro, Fujii Tsutomu

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 5943 - 5951   2019.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.13799

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  37. Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma Reviewed

    Uno Yasuo, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6015 - 6023   2019.11

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.21873/anticanres.13807

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  38. Novel implications of combined arterial resection for locally advanced pancreatic cancer in the era of newer chemo-regimens Reviewed

    Sonohara Fuminori, Yamada Suguru, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    EJSO   Vol. 45 ( 10 ) page: 1895 - 1900   2019.10

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ejso.2019.05.019

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  39. Incorporating molecular biomarkers into clinical practice for gastric cancer Reviewed

    Nakamura Shunsuke, Kanda Mitsuro, Kodera Yasuhiro

    EXPERT REVIEW OF ANTICANCER THERAPY   Vol. 19 ( 9 ) page: 757 - 771   2019.9

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14737140.2019.1659136

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  40. Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer Reviewed

    Kato Yoshiyasu, Yamada Suguru, Tashiro Mitsuru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HPB   Vol. 21 ( 9 ) page: 1211 - 1218   2019.9

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.hpb.2019.01.012

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  41. Recent advances in molecular biomarkers for patients with hepatocellular carcinoma Reviewed

    Umeda Shinichi, Kanda Mitsuro, Kodera Yasuhiro

    EXPERT REVIEW OF MOLECULAR DIAGNOSTICS   Vol. 19 ( 8 ) page: 725 - 738   2019.8

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/14737159.2019.1638254

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  42. Functions of FRAS1 as a driver gene of liver metastasis from gastric cancer analyzed by the genome editing technology Reviewed

    Umeda Shinichi, Kanda Mitsuro, Tanaka Haruyoshi, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER RESEARCH   Vol. 79 ( 13 )   2019.7

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1158/1538-7445.AM2019-863

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  43. Long-lasting discussion: Adverse effects of intraoperative blood loss and allogeneic transfusion on prognosis of patients with gastric cancer Reviewed

    Nakanishi Koki, Kanda Mitsuro, Kodera Yasuhiro

    WORLD JOURNAL OF GASTROENTEROLOGY   Vol. 25 ( 22 ) page: 2743 - 2751   2019.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.3748/wjg.v25.i22.2743

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  44. Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy Reviewed

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF GASTRIC CANCER   Vol. 19 ( 2 ) page: 183 - 192   2019.6

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    DOI: 10.5230/jgc.2019.19.e15

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  45. Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival. Reviewed

    Miwa T, Kanda M, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 5 ) page: 1535 - 1543   2019.5

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    DOI: 10.1245/s10434-019-07166-5

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  46. Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer. Reviewed

    Uno Y, Kanda M, Miwa T, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hattori N, Hayashi M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 3 ) page: 836 - 844   2019.3

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    DOI: 10.1245/s10434-018-07149-y

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  47. Prediction of peritoneal recurrences of gastric cancer by qPCR analysis of peritoneal lavage fluids. Reviewed

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 37 ( 4 )   2019.2

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  48. The Controlling Nutritional Status Score Serves as a Predictor of Short- and Long-Term Outcomes for Patients with Stage 2 or 3 Gastric Cancer: Analysis of a Multi-institutional Data Set. Reviewed

    Ryo S, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 2 ) page: 456-464   2019.2

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    DOI: 10.1245/s10434-018-07121-w

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  49. Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy Reviewed

    Niwa Yukiko, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Hayashi Masamichi, Tashiro Mitsuru, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF TRANSLATIONAL MEDICINE   Vol. 17 ( 1 ) page: 1   2019.1

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    DOI: 10.1186/s12967-018-1762-6

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  50. Optical trocar access for initial trocar placement in laparoscopic gastrointestinal surgery: A propensity score-matching analysis. Reviewed

    Tanaka C, Fujiwara M, Kanda M, Murotani K, Iwata N, Hayashi M, Kobayashi D, Yamada S, Kodera Y

    Asian journal of endoscopic surgery   Vol. 12 ( 1 ) page: 37 - 42   2019.1

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    DOI: 10.1111/ases.12484

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  51. Perioperative and prognostic implication of albumin-bilirubin-TNM score in Child-Pugh class A hepatocellular carcinoma Reviewed

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Sugimoto Hiroyuki, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 3 ( 1 ) page: 65 - 74   2019.1

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    DOI: 10.1002/ags3.12212

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  52. Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines Reviewed

    Miwa Takashi, Kanda Mitsuro, Umeda Shinichi, Tanaka Haruyoshi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   Vol. 33 ( 6 ) page: 1785 - 1792   2019

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    DOI: 10.21873/invivo.11669

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  53. ASO Author Reflections: Troponin I2-A Specific Biomarker for Detection and Prediction of Peritoneal Metastasis in Gastric Cancer. Reviewed

    Sawaki K, Kanda M

    Annals of surgical oncology   Vol. 25   page: 709 - 710   2018.12

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    DOI: 10.1245/s10434-018-6801-2

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  54. RASEF expression correlates with hormone receptor status in breast cancer Reviewed

    Shibata Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Haruyoshi, Umeda Shinichi, Miwa Takashi, Hayashi Masamichi, Inaishi Takahiro, Miyajima Noriyuki, Adachi Yayoi, Takano Yuko, Nakanishi Kenichi, Takeuchi Dai, Noda Sumiyo, Kodera Yasuhiro, Kikumori Toyone

    ONCOLOGY LETTERS   Vol. 16 ( 6 ) page: 7223 - 7230   2018.12

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    DOI: 10.3892/ol.2018.9542

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  55. Pathological tumor infiltrative pattern and sites of initial recurrence in stage II/III gastric cancer: Propensity score matching analysis of a multi-institutional dataset Reviewed

    Nakagawa Nobuhiko, Kanda Mitsuro, Ito Seiji, Mochizuki Yoshinari, Teramoto Hitoshi, Ishigure Kiyoshi, Murai Toshifumi, Asada Takahiro, Ishiyama Akiharu, Matsushita Hidenobu, Tanaka Chie, Kobayashi Daisuke, Fujiwara Michitaka, Murotani Kenta, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 12 ) page: 6020-6029   2018.12

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    DOI: 10.1002/cam4.1868

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  56. Homeobox C10 correlates with the malignant phenotype of gastric cancer and its recurrence and poor survival Reviewed

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1127-1127   2018.12

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  57. FRAS1 expression reflects the malignancy potential of gastric cancer Reviewed

    Umeda Shinichi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128-1128   2018.12

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  58. Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma Reviewed

    Umeda Shinichi, Kanda Mitsuro, Koike Masahiko, Tanaka Haruyoshi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 40 ( 6 ) page: 3772 - 3780   2018.12

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    DOI: 10.3892/or.2018.6742

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  59. Biological significance of ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 (AGAP3) in colorectal cancer (CRC) Reviewed

    Shimizu Dai, Sato Kuniaki, Masuda Takaaki, Otsu Hajime, Kuroda Yousuke, Eguchi Hidetoshi, Kanda Mitsuro, Kodera Yasuhiro, Mimori Koshi

    CANCER SCIENCE   Vol. 109   page: 1235-1235   2018.12

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  60. A New Biomarker for Peritoneal Lavage Using Digital PCR in Patients with Pancreatic Ductal Adenocarcinoma Reviewed

    Suenaga Masaya, Yamada Suguru, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 650-650   2018.12

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  61. Integrated multigene expression panel to prognosticate patients with gastric cancer Reviewed

    Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Hayashi Masamichi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 769 - 769   2018.12

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  62. Troponin I2 as a specific biomarker for prediction of peritoneal metastasis in gastric cancer Reviewed

    Sawaki Koichi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 765 - 765   2018.12

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  63. Pattern-specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer Reviewed

    Tanaka Haruyoshi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128 - 1128   2018.12

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  64. Number of retrieved lymph nodes is an independent prognostic factor after total gastrectomy for patients with stage III gastric cancer: propensity score matching analysis of a multi-institution dataset. Reviewed

    Hayashi S, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association     2018.11

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    DOI: 10.1007/s10120-018-0902-2

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  65. Cutting-edge evidence of adjuvant treatments for gastric cancer Reviewed

    Shimizu Dai, Kanda Mitsuro, Kodera Yasuhiro, Sakamoto Junichi

    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 12 ( 11 ) page: 1109 - 1122   2018.11

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    DOI: 10.1080/17474124.2018.1530985

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  66. Treatment strategy of intraperitoneal and systemic chemotherapy combined with gastrectomy for gastric cancer with peritoneal metastasis Reviewed

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 98-98   2018.11

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  67. Long-term quality of life and nutrition status of the aboral pouch reconstruction after total gastrectomy for gastric cancer: a prospective multicenter observational study (CCOG1505). Reviewed

    Tanaka C, Kanda M, Murotani K, Yoshikawa T, Cho H, Ito Y, Matsui T, Nakayama H, Yamada T, Kobayashi D, Fujiwara M, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association     2018.10

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    DOI: 10.1007/s10120-018-0893-z

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  68. Intraoperative Blood Loss is Associated with Shortened Postoperative Survival of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-institutional Dataset. Reviewed

    Ito Y, Kanda M, Ito S, Mochizuki Y, Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi D, Fujiwara M, Murotani K, Kodera Y

    World journal of surgery     2018.10

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    DOI: 10.1007/s00268-018-4834-0

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  69. Significance of Preoperative Systemic Inflammation Score in Short-Term and Long-Term Outcomes of Patients with Pathological T2-4 Gastric Cancer After Radical Gastrectomy

    Sato Bin, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Iwata Naoki, Hattori Norifumi, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Murotani Kenta, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   Vol. 42 ( 10 ) page: 3277-3285   2018.10

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    DOI: 10.1007/s00268-018-4597-7

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  70. Expression of sushi domain containing two reflects the malignant potential of gastric cancer. Reviewed

    Umeda S, Kanda M, Miwa T, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hattori N, Hayashi M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Cancer medicine   Vol. 7 ( 10 ) page: 5194 - 5204   2018.10

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    DOI: 10.1002/cam4.1793

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  71. SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells. Reviewed

    Kanda M, Tanaka H, Shimizu D, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hattori N, Suenaga M, Hayashi M, Iwata N, Yamada S, Fujiwara M, Kodera Y

    Oncogene   Vol. 37 ( 39 ) page: 5355 - 5366   2018.9

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    DOI: 10.1038/s41388-018-0335-8

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  72. Comparison of the Survival Outcomes of Pancreatic Cancer and Intraductal Papillary Mucinous Neoplasms.

    Yamada S, Fujii T, Hirakawa A, Takami H, Suenaga M, Hayashi M, Niwa Y, Hattori N, Iwata N, Kanda M, Tanaka C, Kobayashi D, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Pancreas   Vol. 47 ( 8 ) page: 974-979   2018.9

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    DOI: 10.1097/MPA.0000000000001110

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  73. Synaptotagmin XIII expression and peritoneal metastasis in gastric cancer

    Kanda M., Shimizu D., Tanaka H., Tanaka C., Kobayashi D., Hayashi M., Takami H., Niwa Y., Yamada S., Fujii T., Sugimoto H., Kodera Y.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 10 ) page: 1349-1358   2018.9

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    DOI: 10.1002/bjs.10876

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  74. Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer Reviewed

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Umeda Shinichi, Shibata Masahiro, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    MOLECULAR CANCER RESEARCH   Vol. 16 ( 9 ) page: 1420 - 1429   2018.9

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    DOI: 10.1158/1541-7786.MCR-17-0467

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  75. Efficacy of enteral nutrients containing beta-hydroxy-beta-methylbutyrate, glutamine, and arginine for the patients with anastomotic leakage after gastrectomy: study protocol of a multicenter phase II clinical trial

    Kanda Mitsuro, Tanaka Chie, Murotani Kenta, Kobayashi Daisuke, Ito Seiji, Mochizuki Yoshinari, Ishigure Kiyoshi, Ishiyama Akiharu, Teramoto Hitoshi, Murai Toshifumi, Asada Takahiro, Matsushita Hidenobu, Fujiwara Michitaka, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 3 ) page: 351-355   2018.8

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    DOI: 10.18999/nagjms.80.3.351

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  76. Randomized Phase II Trial of CapOX plus Bevacizumab and CapIRI plus Bevacizumab as First-Line Treatment for Japanese Patients with Metastatic Colorectal Cancer (CCOG-1201 Study)

    Nakayama Goro, Mitsuma Ayako, Sunagawa Yuki, Ishigure Kiyoshi, Yokoyama Hiroyuki, Matsui Takanori, Nakayama Hiroshi, Nakata Kazuhiko, Ishiyama Akiharu, Asada Takahiro, Umeda Shinichi, Ezaka Kazuhiro, Hattori Norifumi, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    ONCOLOGIST   Vol. 23 ( 8 ) page: 919-927   2018.8

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    DOI: 10.1634/theoncologist.2017-0640

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  77. Impact of the Controlling Nutritional Status Score on the Prognosis After Curative Resection of Pancreatic Ductal Adenocarcinoma Reviewed

    Kato Yoshiyasu, Yamada Suguru, Suenaga Masaya, Takami Hideki, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 7 ) page: 823 - 829   2018.8

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    DOI: 10.1097/MPA.0000000000001105

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  78. Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer Reviewed

    Sawaki Koichi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 7 ) page: 2083 - 2090   2018.7

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    DOI: 10.1245/s10434-018-6480-z

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  79. Risk Factors for Peritoneal Recurrence in Stage II to III Colon Cancer

    Mayanagi Shuhei, Kashiwabara Kosuke, Honda Michitaka, Oba Koji, Aoyama Toru, Kanda Mitsuro, Maeda Hiromichi, Hamada Chikuma, Sadahiro Sotaro, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    DISEASES OF THE COLON & RECTUM   Vol. 61 ( 7 ) page: 803-808   2018.7

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    DOI: 10.1097/DCR.0000000000001002

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  80. Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer Reviewed

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Suenaga Masaya, Hayashi Masamichi, Takami Hideki, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 9846   2018.6

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    DOI: 10.1038/s41598-018-28253-9

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  81. Emerging evidence of the molecular landscape specific for hematogenous metastasis from gastric cancer Reviewed

    Shimizu Dai, Kanda Mitsuro, Kodera Yasuhiro

    WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY   Vol. 10 ( 6 ) page: 124 - 136   2018.6

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    DOI: 10.4251/wjgo.v10.i6.124

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  82. A novel dual-marker expression panel for easy and accurate risk stratification of patients with gastric cancer

    Kanda Mitsuro, Murotani Kenta, Tanaka Haruyoshi, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Hattori Norifumi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 6 ) page: 2463-2471   2018.6

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    DOI: 10.1002/cam4.1522

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  83. Significance of Lysyl oxidase-like 2 gene expression on the epithelial-mesenchymal status of hepatocellular carcinoma Reviewed

    Ninomiya Go, Yamada Suguru, Hayashi Masamichi, Takeda Shigeomi, Suenaga Masaya, Takami Hideki, Kanda Mitsuro, Iwata Naoki, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 39 ( 6 ) page: 2664 - 2672   2018.6

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    DOI: 10.3892/or.2018.6349

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  84. Postoperative adalimumab maintenance therapy for Japanese patients with Crohn's disease: a single-center, single-arm phase II trial (CCOG-1107 study) Reviewed

    Asada Takahiro, Nakayama Goro, Tanaka Chie, Kobayashi Daisuke, Ezaka Kazuhiro, Hattori Norifumi, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    SURGERY TODAY   Vol. 48 ( 6 ) page: 609 - 617   2018.6

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    DOI: 10.1007/s00595-018-1634-y

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  85. IDENTIFICATION OF MOLECULES DRIVING HEPATIC METASTASIS FORMATION OF GASTRIC CANCER CELLS

    Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    GUT   Vol. 67   page: A5-A5   2018.6

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    DOI: 10.1136/gutjnl-2018-IDDFabstracts.12

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  86. A phase II trial to evaluate the efficacy of panitumumab combined with fluorouracil-based chemotherapy for metastatic colorectal cancer: the PF trial

    Munemoto Yoshinori, Kanda Mitsuro, Oba Koji, Kim Ho Min, Takemoto Hiroyoshi, Denda Tadamichi, Nagata Naoki, Takano Nao, Fukunaga Mutsumi, Kataoka Masato, Tokunaga Yukihiko, Sakamoto Junichi, Mishima Hideyuki

    CANCER CHEMOTHERAPY AND PHARMACOLOGY   Vol. 81 ( 5 ) page: 829-838   2018.5

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    DOI: 10.1007/s00280-018-3556-1

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  87. Integrated multigene expression panel to prognosticate patients with gastric cancer.

    Kanda M, Murotani K, Tanaka H, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Hattori N, Suenaga M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Oncotarget   Vol. 9 ( 27 ) page: 18775-18785   2018.4

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    DOI: 10.18632/oncotarget.24661

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  88. Emerging evidence of molecular biomarkers in hepatocellular carcinoma. Reviewed

    Umeda S, Kanda M, Kodera Y

    Histology and histopathology   Vol. 33 ( 4 ) page: 343 - 355   2018.4

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    DOI: 10.14670/HH-11-936

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  89. Clinical Signatures of Mucinous and Poorly Differentiated Subtypes of Colorectal Adenocarcinomas by a Propensity Score Analysis of an Independent Patient Database from Three Phase III Trials

    Kanda Mitsuro, Oba Koji, Aoyama Toru, Kashiwabara Kosuke, Mayanagi Shuhei, Maeda Hiromichi, Honda Michitaka, Hamada Chikuma, Sadahiro Sotaro, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    DISEASES OF THE COLON & RECTUM   Vol. 61 ( 4 ) page: 461-471   2018.4

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    DOI: 10.1097/DCR.0000000000001022

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  90. A randomized phase II multicenter trial to explore efficacy of weekly intraperitoneal in comparison with intravenous paclitaxel administered immediately after gastrectomy to the patients with high risk of peritoneal recurrence: final results of the INPACT trial.

    Takahashi N, Kanda M, Yoshikawa T, Takiguchi N, Fujitani K, Miyamoto K, Ito Y, Takayama O, Imano M, Mitsumori N, Sakamoto J, Morita S, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association     2018.3

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    DOI: 10.1007/s10120-018-0817-y

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  91. Identification of a novel molecule target for the diagnosis, prediction, and treatment of hepatic metastasis of gastric cancer. Reviewed

    Kanda Mitsuro, Tanaka Haruyoshi, Miwa Takashi, Kobayashi Daisuke, Tanaka Chie, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  92. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer. Reviewed

    Yamada Suguru, Fujii Tsutomu, Takano Nao, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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  93. Clinical implication of nutrition for neoadjuvant therapy and impact of nutritional support in pancreatic cancer. Reviewed

    Tashiro Mitsuru, Yamada Suguru, Fujii Tsutomu, Hattori Norifumi, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 )   2018.2

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  94. Review of recent molecular landscape knowledge of gastric cancer. Reviewed

    Shimizu D, Kanda M, Kodera Y

    Histology and histopathology   Vol. 33 ( 1 ) page: 11 - 26   2018.1

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    DOI: 10.14670/HH-11-898

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  95. Effectiveness of plasma activated lactated Ringer's solution on pancreatic cancer cells in vitro and in vivo

    Sato Yusuke, Yamada Suguru, Takeda Shigeomi, Kanda Mitsuo, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 707-707   2018.1

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  96. Oncogenic function of miR-23b-3p in hepatocellular carcinoma

    Masamichi Hayashi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1123-1123   2018.1

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  97. Perioperative Serum Carcinoembryonic Antigen Levels Predict Recurrence and Survival of Patients with Pathological T2-4 Gastric Cancer Treated with Curative Gastrectomy. Reviewed

    Uda H, Kanda M, Tanaka C, Kobayashi D, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 35 ( 1 ) page: 55-63   2018

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    DOI: 10.1159/000471931

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  98. Review of recent efforts to discover biomarkers for early detection, monitoring, prognosis, and prediction of treatment responses of patients with gastric cancer Reviewed

    Sawaki Koichi, Kanda Mitsuro, Kodera Yasuhiro

    EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY   Vol. 12 ( 7 ) page: 657 - 670   2018

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    DOI: 10.1080/17474124.2018.1489233

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  99. Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification Reviewed

    Morimoto Daishi, Yamada Suguru, Murotani Kenta, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tashiro Mitsuru, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 10 ) page: 1350-1356   2018

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    DOI: 10.1097/MPA.0000000000001186

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  100. Genome-wide Discovery of a Novel Gene-expression Signature for the Identification of Lymph Node Metastasis in Esophageal Squamous Cell Carcinoma. Reviewed

    Sonohara F, Gao F, Iwata N, Kanda M, Koike M, Takahashi N, Yamada Y, Kodera Y, Wang X, Goel A

    Annals of surgery     2017.12

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    DOI: 10.1097/SLA.0000000000002622

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  101. Randomized phase II study of daily and alternate-day administration of S-1 for advanced gastric cancer (JFMC43-1003)

    Tanaka Hiroaki, Kanda Mitsuro, Morita Satoshi, Taguri Masataka, Nishikawa Kazuhiro, Shimada Mitsuo, Muguruma Kazuya, Koeda Keisuke, Takahashi Masazumi, Nakamori Mikihito, Konno Hiroyuki, Tsuji Akihito, Hosoya Yoshinori, Shirasaka Tetsuhiko, Yamamitsu Susumu, Sowa Michio, Kitajima Masaki, Okajima Masazumi, Kobayashi Michiya, Sakamoto Junichi, Saji Shigetoyo, Hirakawa Kosei

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 22 ( 6 ) page: 1052-1059   2017.12

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    DOI: 10.1007/s10147-017-1157-3

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  102. Prevalence of Helicobacter Pylori Infection in Dyspeptic Patients in Andkhoy Afghanistan

    Hamrah MH, Hamrah MS, Hassan Hamrah M, Kanda M, Hamrah AE, Dahi AE, Homayoun F, Hamrah MH, Fotouhi A, Sakamoto J

    Asian Pacific journal of cancer prevention : APJCP   Vol. 18 ( 11 ) page: 3123-3127   2017.11

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    DOI: 10.22034/APJCP.2017.18.11.3123

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  103. Development and validation of a prognostic nomogram for colorectal cancer after radical resection based on individual patient data from three large-scale phase III trials

    Honda Michitaka, Oba Koji, Akiyoshi Takashi, Maeda Hiromichi, Kashiwabara Kosuke, Kanda Mitsuro, Mayanagi Shuhei, Aoyama Toru, Hamada Chikuma, Sadahiro Sotaro, Fukunaga Yosuke, Ueno Masashi, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    ONCOTARGET   Vol. 8 ( 58 ) page: 99150-99160   2017.11

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    DOI: 10.18632/oncotarget.21845

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  104. FBXO50 Enhances the Malignant Behavior of Gastric Cancer Cells. Reviewed

    Miwa T, Kanda M, Tanaka H, Tanaka C, Kobayashi D, Umeda S, Iwata N, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 12 ) page: 3771 - 3779   2017.11

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    DOI: 10.1245/s10434-017-5882-7

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  105. Clinical impact of postoperative surgical complications on the colorectal cancer survival and recurrence: Analyses of pooled individual patients' data from three large phase III randomized trials

    Aoyama T., Oba K., Honda M., Sadahiro S., Hamada C., Mayanagi S., Kanda M., Maeda H., Sakamoto J., Saji S., Yoshikawa T.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.11

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  106. Clinical impact of tumor location on the colon cancer survival and recurrence: analyses of pooled data from three large phase III randomized clinical trials

    Aoyama Toru, Kashiwabara Kosuke, Oba Koji, Honda Michitaka, Sadahiro Sotaro, Hamada Chikuma, Maeda Hiromichi, Mayanagi Shuhei, Kanda Mitsuro, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    CANCER MEDICINE   Vol. 6 ( 11 ) page: 2523-2530   2017.11

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    DOI: 10.1002/cam4.1208

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  107. FAM46C Serves as a Predictor of Hepatic Recurrence in Patients with Resectable Gastric Cancer. Reviewed

    Tanaka H, Kanda M, Shimizu D, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Niwa Y, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 11 ) page: 3438 - 3445   2017.10

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    DOI: 10.1245/s10434-016-5636-y

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  108. Identification of <i>NCCRP1</i> as an epigenetically regulated tumor suppressor and biomarker for malignant phenotypes of squamous cell carcinoma of the esophagus. Reviewed

    Miwa T, Kanda M, Koike M, Iwata N, Tanaka H, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Yamada S, Fujii T, Fujiwara M, Kodera Y

    Oncology letters   Vol. 14 ( 4 ) page: 4822 - 4828   2017.10

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    DOI: 10.3892/ol.2017.6753

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  109. Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society. Reviewed

    Yamada S, Fujii T, Takami H, Hayashi M, Iwata N, Kanda M, Tanaka C, Sugimoto H, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Surgery   Vol. 162 ( 4 ) page: 784 - 791   2017.10

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    DOI: 10.1016/j.surg.2017.04.023

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  110. An integrated multigene expression panel to predict long-term survival after curative hepatectomy in patients with hepatocellular carcinoma. Reviewed

    Kanda M, Murotani K, Sugimoto H, Miwa T, Umeda S, Suenaga M, Hayashi M, Hattori N, Tanaka C, Kobayashi D, Yamada S, Fujiwara M, Kodera Y

    Oncotarget   Vol. 8 ( 41 ) page: 71070-71079   2017.9

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    DOI: 10.18632/oncotarget.20369

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  111. Preoperative Albumin-Bilirubin Grade Predicts Recurrences After Radical Gastrectomy in Patients with pT2-4 Gastric Cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Uda H, Inaoka K, Tanaka Y, Hayashi M, Iwata N, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of surgery     2017.9

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    DOI: 10.1007/s00268-017-4234-x

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  112. Downregulation of GPR155 as a prognostic factor after curative resection of hepatocellular carcinoma. Reviewed

    Umeda S, Kanda M, Sugimoto H, Tanaka H, Hayashi M, Yamada S, Fujii T, Takami H, Niwa Y, Iwata N, Tanaka C, Kobayashi D, Fujiwara M, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 610   2017.9

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    DOI: 10.1186/s12885-017-3629-2

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  113. Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells. Reviewed

    Shibata M, Kanda M, Tanaka H, Umeda S, Miwa T, Shimizu D, Hayashi M, Inaishi T, Miyajima N, Adachi Y, Takano Y, Nakanishi K, Takeuchi D, Noda S, Kodera Y, Kikumori T

    Oncology reports   Vol. 38 ( 3 ) page: 1760 - 1766   2017.9

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    DOI: 10.3892/or.2017.5800

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  114. Involvement of the immunoregulator MZB1 in progression of gastric cancer

    Tanaka Y., Kanda M., Tanaka C., Kobayashi D., Tanaka H., Takami H., Hayashi M., Iwata N., Niwa Y., Yamada S., Nakayama G., Sugimoto H., Koike M., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  115. Nutritional recovery after open and laparoscopic distal gastrectomy for early gastric cancer: A prospective multicenter comparative trial (CCOG1204)

    Tanaka C., Kanda M., Misawa K., Ito S., Ito Y., Mochizuki Y., Ishigure K., Yaguchi T., Teramoto J., Nakayama H., Kawase Y., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  116. Usefulness of preoperative estimated glomerular filtration rate to predict complications after curative gastrectomy in patients with clinical T2-4 gastric cancer. Reviewed

    Tanaka Y, Kanda M, Tanaka C, Kobayashi D, Mizuno A, Iwata N, Hayashi M, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   Vol. 20 ( 4 ) page: 736 - 743   2017.7

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    DOI: 10.1007/s10120-016-0657-6

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  117. Impact of postoperative complications on the colorectal cancer survival and recurrence: analyses of pooled individual patients' data from three large phase III randomized trials

    Aoyama Toru, Oba Koji, Honda Michitaka, Sadahiro Sotaro, Hamada Chikuma, Mayanagi Shuhei, Kanda Mitsuro, Maeda Hiromichi, Kashiwabara Kosuke, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    CANCER MEDICINE   Vol. 6 ( 7 ) page: 1573-1580   2017.7

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    DOI: 10.1002/cam4.1126

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  118. Expression of regulatory factor X1 can predict the prognosis of breast cancer. Reviewed

    Shibata M, Kanda M, Shimizu D, Tanaka H, Umeda S, Hayashi M, Inaishi T, Miyajima N, Adachi Y, Takano Y, Nakanishi K, Takeuchi D, Noda S, Kodera Y, Kikumori T

    Oncology letters   Vol. 13 ( 6 ) page: 4334 - 4340   2017.6

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    DOI: 10.3892/ol.2017.6005

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  119. Stapling an extracorporeal Billroth-I anastomosis by the complete double stapling technique after laparoscopy-assisted distal gastrectomy. Reviewed

    Tanaka C, Fujiwara M, Kanda M, Murotani K, Iwata N, Hayashi M, Kobayashi D, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujii T, Kodera Y

    Asian journal of endoscopic surgery   Vol. 10 ( 2 ) page: 137 - 142   2017.5

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    DOI: 10.1111/ases.12357

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  120. Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer. Reviewed

    Takeda S, Yamada S, Hattori N, Nakamura K, Tanaka H, Kajiyama H, Kanda M, Kobayashi D, Tanaka C, Fujii T, Fujiwara M, Mizuno M, Hori M, Kodera Y

    Annals of surgical oncology   Vol. 24 ( 5 ) page: 1188 - 1194   2017.5

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    DOI: 10.1245/s10434-016-5759-1

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  121. Clinical utility of the platelet-lymphocyte ratio as a predictor of postoperative complications after radical gastrectomy for clinical T2-4 gastric cancer. Reviewed

    Inaoka K, Kanda M, Uda H, Tanaka Y, Tanaka C, Kobayashi D, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    World journal of gastroenterology   Vol. 23 ( 14 ) page: 2519-2526   2017.4

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    DOI: 10.3748/wjg.v23.i14.2519

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  122. The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902). Reviewed

    Nakayama G, Ishigure K, Yokoyama H, Uehara K, Kojima H, Ishiyama A, Hayashi N, Takano N, Hattori N, Kobayashi D, Tanaka C, Hayashi M, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Fujii T, Murotani K, Ando Y, Kodera Y

    BMC cancer   Vol. 17 ( 1 ) page: 243   2017.4

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    DOI: 10.1186/s12885-017-3245-1

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  123. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma: A retrospective cohort study. Reviewed

    Ninomiya G, Fujii T, Yamada S, Yabusaki N, Suzuki K, Iwata N, Kanda M, Hayashi M, Tanaka C, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of surgery (London, England)   Vol. 39   page: 45 - 51   2017.3

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    DOI: 10.1016/j.ijsu.2017.01.075

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  124. Nutritional Recovery after Open and Laparoscopic Distal Gastrectomy for Early Gastric Cancer: A Prospective Multicenter Comparative Trial (CCOG1204).

    Matsushita H, Tanaka C, Murotani K, Misawa K, Ito S, Ito Y, Kanda M, Mochizuki Y, Ishigure K, Yaguchi T, Teramoto J, Nakayama H, Kawase Y, Fujiwara M, Kodera Y

    Digestive surgery     2017.2

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    DOI: 10.1159/000458714

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  125. GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer. Reviewed

    Shimizu D, Kanda M, Tanaka H, Kobayashi D, Tanaka C, Hayashi M, Iwata N, Niwa Y, Takami H, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    Scientific reports   Vol. 7   page: 42089   2017.2

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    DOI: 10.1038/srep42089

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  126. Esophageal Cancer and associated Factors among Uzbek-Turkmen and Other Ethnic Groups in the Northern Part of Afghanistan

    Hamrah MH, Hamrah MSh, Kanda M, Sakamoto J, Hamrah MH, Hami A, Hamrah AE, Dahi AE, Hamrah MH

    Asian Pacific journal of cancer prevention : APJCP   Vol. 18 ( 2 ) page: 333-337   2017.2

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    DOI: 10.22034/APJCP.2017.18.2.333

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  127. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma. Reviewed

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Asano Tomonari, Takano Nao, Takami Hideki, Iwata Naoki, Kanda Mitsuro, Niwa Yukiko, Hayashi Masamichi, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  128. Conversion surgery for unresectable gastric cancer following complete response of distant metastasis by systemic chemotherapy. Reviewed

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Iwata Naoki, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  129. Clinical implication of inflammation-based prognostic score and perioperative nutrition control in pancreatic cancer. Reviewed

    Takano Nao, Yamada Suguru, Fujii Tsutomu, Tashiro Mitsuru, Tanaka Nobutake, Morimoto Daishi, Ninomiya Go, Niwa Yukiko, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  130. Tumor infiltrative pattern predicts sites of recurrence after curative gastrectomy for gastric cancer. Reviewed

    Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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    DOI: 10.1200/JCO.2017.35.4_suppl.38

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  131. The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy. Reviewed

    Shimizu D, Kanda M, Sugimoto H, Shibata M, Tanaka H, Takami H, Iwata N, Hayashi M, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Koike M, Fujiwara M, Fujii T, Kodera Y

    International journal of oncology   Vol. 50 ( 2 ) page: 381 - 386   2017.2

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    DOI: 10.3892/ijo.2017.3833

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  132. Association of Inflammasome Components in Background Liver with Poor Prognosis After Curatively-resected Hepatocellular Carcinoma.

    Sonohara F, Inokawa Y, Kanda M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Kodera Y, Nomoto S

    Anticancer research   Vol. 37 ( 1 ) page: 293-300   2017.1

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    DOI: 10.21873/anticanres.11320

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  133. Clinical benefits of neoadjuvant chemoradiotherapy for adenocarcinoma of the pancreatic head: an observational study using inverse probability of treatment weighting.

    Fujii T, Satoi S, Yamada S, Murotani K, Yanagimoto H, Takami H, Yamamoto T, Kanda M, Yamaki S, Hirooka S, Kon M, Kodera Y

    Journal of gastroenterology   Vol. 52 ( 1 ) page: 81-93   2017.1

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    DOI: 10.1007/s00535-016-1217-x

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  134. PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma. Reviewed

    Kurimoto K, Hayashi M, Guerrero-Preston R, Koike M, Kanda M, Hirabayashi S, Tanabe H, Takano N, Iwata N, Niwa Y, Takami H, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Fujii T, Fujiwara M, Kodera Y

    Epigenetics   Vol. 12 ( 10 ) page: 865-874   2017

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    DOI: 10.1080/15592294.2017.1365207

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  135. Hazard rate of tumor recurrence over time in patients with colon cancer: implications for postoperative surveillance from three Japanese Foundation for Multi-disciplinary Treatment of Cancer (JFMC) clinical trials

    Maeda Hiromichi, Kashiwabara Kosuke, Aoyama Toru, Oba Koji, Honda Michitaka, Mayanagi Shuhei, Kanda Mitsuro, Hamada Chikuma, Sadahiro Sotaro, Sakamoto Junichi, Saji Shigetoyo, Yoshikawa Takaki

    JOURNAL OF CANCER   Vol. 8 ( 19 ) page: 4057-4064   2017

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    DOI: 10.7150/jca.21365

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  136. Significance of SYT8 For the Detection, Prediction, and Treatment of Peritoneal Metastasis From Gastric Cancer.

    Kanda M, Shimizu D, Tanaka H, Tanaka C, Kobayashi D, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgery     2016.12

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    DOI: 10.1097/SLA.0000000000002096

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  137. Pharmacokinetic dose adjustment of 5-FU in modified FOLFOX7 plus bevacizumab for metastatic colorectal cancer in Japanese patients: a-JUST phase II clinical trial. Reviewed

    Denda T, Kanda M, Morita Y, Kim HM, Kashiwada T, Matsuda C, Fujieda S, Nakata K, Murotani K, Oba K, Sakamoto J, Mishima H

    Cancer chemotherapy and pharmacology   Vol. 78 ( 6 ) page: 1253-1261   2016.12

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    DOI: 10.1007/s00280-016-3184-6

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  138. Prognostic significance of AKR1B10 gene expression in hepatocellular carcinoma and surrounding non-tumorous liver tissue.

    Sonohara F, Inokawa Y, Hishida M, Kanda M, Nishikawa Y, Yamada S, Fujii T, Sugimoto H, Kodera Y, Nomoto S

    Oncology letters   Vol. 12 ( 6 ) page: 4821-4828   2016.12

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    DOI: 10.3892/ol.2016.5240

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  139. Lymph node ratio as parameter of regional lymph node involvement in pancreatic cancer.

    Yamada S, Fujii T, Hirakawa A, Kanda M, Sugimoto H, Kodera Y

    Langenbeck's archives of surgery   Vol. 401 ( 8 ) page: 1143-1152   2016.12

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    DOI: 10.1007/s00423-016-1412-5

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  140. A resected case of symptomatic acinar cell cystadenoma of the pancreas displacing the main pancreatic duct.

    Tanaka H, Hatsuno T, Kinoshita M, Hasegawa K, Ishihara H, Takano N, Shimoyama S, Nakayama H, Kataoka M, Ichihara S, Kanda M, Kodera Y, Kondo K

    Surgical case reports   Vol. 2 ( 1 ) page: 39   2016.12

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    DOI: 10.1186/s40792-016-0166-1

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  141. Prognostic relevance of <i>SAMSN1</i> expression in gastric cancer.

    Kanda M, Shimizu D, Sueoka S, Nomoto S, Oya H, Takami H, Ezaka K, Hashimoto R, Tanaka Y, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncology letters   Vol. 12 ( 6 ) page: 4708-4716   2016.12

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    DOI: 10.3892/ol.2016.5233

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  142. Erratum to: The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer. Reviewed

    Kataoka M, Kanda M, Ishigure K, Matsuoka H, Sato Y, Takahashi T, Tanaka C, Deguchi T, Shibata Y, Sato M, Inagaki H, Matsui T, Kondo A, Takano N, Tanaka H, Sakamoto J, Oba K, Kondo K

    Annals of surgical oncology   Vol. 23 ( Suppl 5 ) page: 1064   2016.12

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    DOI: 10.1245/s10434-016-5593-5

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  143. Epigenetic suppression of the immunoregulator MZB1 is associated with the malignant phenotype of gastric cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Tanaka H, Shimizu D, Shibata M, Takami H, Hayashi M, Iwata N, Niwa Y, Yamada S, Fujii T, Nakayama G, Fujiwara M, Kodera Y

    International journal of cancer   Vol. 139 ( 10 ) page: 2290-8   2016.11

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    DOI: 10.1002/ijc.30286

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  144. Molecular alterations in the carcinogenesis and progression of hepatocellular carcinoma: Tumor factors and background liver factors.

    Inokawa Y, Inaoka K, Sonohara F, Hayashi M, Kanda M, Nomoto S

    Oncology letters   Vol. 12 ( 5 ) page: 3662-3668   2016.11

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    DOI: 10.3892/ol.2016.5141

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  145. Predictive value of drain amylase content for peripancreatic inflammatory fluid collections after laparoscopic (assisted) distal gastrectomy. Reviewed

    Kanda M, Fujiwara M, Tanaka C, Kobayashi D, Iwata N, Mizuno A, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Kodera Y

    Surgical endoscopy   Vol. 30 ( 10 ) page: 4353-62   2016.10

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    DOI: 10.1007/s00464-016-4753-9

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  146. Modified two-dimensional response as surrogate marker of overall survival in patients with metastatic colorectal cancer.

    Nakayama G, Fujii T, Murotani K, Uehara K, Hattori N, Hayashi M, Tanaka C, Kobayashi D, Kanda M, Yamada S, Sugimoto H, Koike M, Fujiwara M, Ando Y, Kodera Y

    Cancer science   Vol. 107 ( 10 ) page: 1492-1498   2016.10

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    DOI: 10.1111/cas.13023

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  147. The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer. Reviewed

    Kataoka M, Kanda M, Ishigure K, Matsuoka H, Sato Y, Takahashi T, Tanaka C, Deguchi T, Shibata Y, Sato M, Inagaki H, Matsui T, Kondo A, Takano N, Tanaka H, Sakamoto J, Oba K, Kondo K

    Annals of surgical oncology     2016.9

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    DOI: 10.1245/s10434-016-5557-9

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  148. Proposal of the Coagulation Score as a Predictor for Short-Term and Long-Term Outcomes of Patients with Resectable Gastric Cancer. Reviewed

    Kanda M, Tanaka C, Kobayashi D, Mizuno A, Tanaka Y, Takami H, Iwata N, Hayashi M, Niwa Y, Yamada S, Fujii T, Sugimoto H, Murotani K, Fujiwara M, Kodera Y

    Annals of surgical oncology     2016.9

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    DOI: 10.1245/s10434-016-5544-1

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  149. Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer. Reviewed

    Kanda M, Shimizu D, Fujii T, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of oncology   Vol. 49 ( 3 ) page: 1195-202   2016.9

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    DOI: 10.3892/ijo.2016.3584

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  150. Correlation Between Poor Prognosis and Lower TPPP Gene Expression in Hepatocellular Carcinoma.

    Inokawa Y, Sonohara F, Kanda M, Hayashi M, Nishikawa Y, Sugimoto H, Kodera Y, Nomoto S

    Anticancer research   Vol. 36 ( 9 ) page: 4639-45   2016.9

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    DOI: 10.21873/anticanres.11014

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  151. Molecular mechanisms of peritoneal dissemination in gastric cancer. Reviewed

    Kanda M, Kodera Y

    World journal of gastroenterology   Vol. 22 ( 30 ) page: 6829-40   2016.8

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    DOI: 10.3748/wjg.v22.i30.6829

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  152. Neurotrophin Receptor-Interacting Melanoma Antigen-Encoding Gene Homolog is Associated with Malignant Phenotype of Gastric Cancer. Reviewed

    Kanda M, Shimizu D, Fujii T, Tanaka H, Tanaka Y, Ezaka K, Shibata M, Takami H, Hashimoto R, Sueoka S, Iwata N, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( Suppl 4 ) page: 532-539   2016.8

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    DOI: 10.1245/s10434-016-5375-0

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  153. The significance of relative dose intensity in adjuvant chemotherapy of pancreatic ductal adenocarcinoma-including the analysis of clinicopathological factors influencing relative dose intensity.

    Yabusaki N, Fujii T, Yamada S, Murotani K, Sugimoto H, Kanda M, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Medicine   Vol. 95 ( 29 ) page: e4282   2016.7

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    DOI: 10.1097/MD.0000000000004282

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  154. Overexpression of ankyrin1 promotes pancreatic cancer cell growth. Reviewed

    Omura N, Mizuma M, MacGregor A, Hong SM, Ayars M, Almario JA, Borges M, Kanda M, Li A, Vincent A, Maitra A, Goggins M

    Oncotarget   Vol. 7 ( 23 ) page: 34977-87   2016.6

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    DOI: 10.18632/oncotarget.9009

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  155. Nutritional predictors for postoperative short-term and long-term outcomes of patients with gastric cancer. Reviewed

    Kanda M, Mizuno A, Tanaka C, Kobayashi D, Fujiwara M, Iwata N, Hayashi M, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Takami H, Niwa Y, Murotani K, Kodera Y

    Medicine   Vol. 95 ( 24 ) page: e3781   2016.6

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    DOI: 10.1097/MD.0000000000003781

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  156. Tumor Infiltrative Pattern Predicts Sites of Recurrence After Curative Gastrectomy for Stages 2 and 3 Gastric Cancer. Reviewed

    Kanda M, Mizuno A, Fujii T, Shimoyama Y, Yamada S, Tanaka C, Kobayashi D, Koike M, Iwata N, Niwa Y, Hayashi M, Takami H, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( 6 ) page: 1934-40   2016.6

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    DOI: 10.1245/s10434-016-5102-x

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  157. Adverse impact of low skeletal muscle index on the prognosis of hepatocellular carcinoma after hepatic resection.

    Yabusaki N, Fujii T, Yamada S, Suzuki K, Sugimoto H, Kanda M, Nakayama G, Koike M, Fujiwara M, Kodera Y

    International journal of surgery (London, England)   Vol. 30   page: 136-42   2016.6

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    DOI: 10.1016/j.ijsu.2016.04.049

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  158. Clinical Implication of Inflammation-Based Prognostic Score in Pancreatic Cancer: Glasgow Prognostic Score Is the Most Reliable Parameter.

    Yamada S, Fujii T, Yabusaki N, Murotani K, Iwata N, Kanda M, Tanaka C, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Medicine   Vol. 95 ( 18 ) page: e3582   2016.5

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    DOI: 10.1097/MD.0000000000003582

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  159. Metastatic pathway-specific transcriptome analysis identifies MFSD4 as a putative tumor suppressor and biomarker for hepatic metastasis in patients with gastric cancer. Reviewed

    Kanda M, Shimizu D, Tanaka H, Shibata M, Iwata N, Hayashi M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncotarget   Vol. 7 ( 12 ) page: 13667-79   2016.3

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    DOI: 10.18632/oncotarget.7269

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  160. S-1 plus nab-paclitaxel is a promising regimen for pancreatic cancer in a preclinical model.

    Suenaga M, Yamada S, Fujii T, Tanaka C, Kanda M, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Journal of surgical oncology   Vol. 113 ( 4 ) page: 413-9   2016.3

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    DOI: 10.1002/jso.24147

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  161. NRAGE promotes the malignant phenotype of hepatocellular carcinoma.

    Shimizu D, Kanda M, Sugimoto H, Sueoka S, Takami H, Ezaka K, Tanaka Y, Hashimoto R, Okamura Y, Iwata N, Tanaka C, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Oncology letters   Vol. 11 ( 3 ) page: 1847-1854   2016.3

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    DOI: 10.3892/ol.2016.4120

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  162. Comparison of the international consensus guidelines for predicting malignancy in intraductal papillary mucinous neoplasms.

    Yamada S, Fujii T, Murotani K, Kanda M, Sugimoto H, Nakayama G, Koike M, Fujiwara M, Nakao A, Kodera Y

    Surgery   Vol. 159 ( 3 ) page: 878-84   2016.3

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    DOI: 10.1016/j.surg.2015.08.042

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  163. Short-term outcomes after conventional transthoracic esophagectomy.

    Niwa Y, Koike M, Hattori M, Iwata N, Takami H, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    Nagoya journal of medical science   Vol. 78 ( 1 ) page: 69-78   2016.2

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  164. Modified Blumgart Suturing Technique for Remnant Closure After Distal Pancreatectomy: a Propensity Score-Matched Analysis.

    Fujii T, Yamada S, Murotani K, Sugimoto H, Hattori M, Kanda M, Takami H, Nakayama G, Nomoto S, Fujiwara M, Nakao A, Kodera Y

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract   Vol. 20 ( 2 ) page: 374-84   2016.2

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    DOI: 10.1007/s11605-015-2980-3

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  165. The Prognostic Relevance of Subcarinal Lymph Node Dissection in Esophageal Squamous Cell Carcinoma.

    Niwa Y, Koike M, Hattori M, Iwata N, Takami H, Hayashi M, Tanaka C, Kobayashi D, Kanda M, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    Annals of surgical oncology   Vol. 23 ( 2 ) page: 611-8   2016.2

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    DOI: 10.1245/s10434-015-4819-2

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  166. Preoperative Identification of a Prognostic Factor for Pancreatic Neuroendocrine Tumors Using Multiphase Contrast-Enhanced Computed Tomography.

    Yamada S, Fujii T, Suzuki K, Inokawa Y, Kanda M, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Nakao A, Kodera Y

    Pancreas   Vol. 45 ( 2 ) page: 198-203   2016.2

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    DOI: 10.1097/MPA.0000000000000443

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  167. Adverse Effects of Intraoperative Blood Loss on Long-Term Outcomes after Curative Gastrectomy of Patients with Stage II/III Gastric Cancer.

    Mizuno A, Kanda M, Kobayashi D, Tanaka C, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Digestive surgery   Vol. 33 ( 2 ) page: 121-8   2016

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    DOI: 10.1159/000443219

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  168. Oral Food Intake Versus Fasting on Postoperative Pancreatic Fistula After Distal Pancreatectomy: A Multi-Institutional Randomized Controlled Trial.

    Fujii T, Yamada S, Murotani K, Okamura Y, Ishigure K, Kanda M, Takeda S, Morita S, Nakao A, Kodera Y

    Medicine   Vol. 94 ( 52 ) page: e2398   2015.12

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    DOI: 10.1097/MD.0000000000002398

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  169. CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence.

    Suenaga M, Yamada S, Fuchs BC, Fujii T, Kanda M, Tanaka C, Kobayashi D, Fujiwara M, Tanabe KK, Kodera Y

    Journal of surgical oncology   Vol. 112 ( 6 ) page: 622-8   2015.11

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    DOI: 10.1002/jso.24056

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  170. Influence of Food Intake on the Healing Process of Postoperative Pancreatic Fistula After Pancreatoduodenectomy: A Multi-institutional Randomized Controlled Trial.

    Fujii T, Nakao A, Murotani K, Okamura Y, Ishigure K, Hatsuno T, Sakai M, Yamada S, Kanda M, Sugimoto H, Nomoto S, Takeda S, Morita S, Kodera Y

    Annals of surgical oncology   Vol. 22 ( 12 ) page: 3905-12   2015.11

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    DOI: 10.1245/s10434-015-4496-1

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  171. Effectiveness of plasma treatment on pancreatic cancer cells.

    Hattori N, Yamada S, Torii K, Takeda S, Nakamura K, Tanaka H, Kajiyama H, Kanda M, Fujii T, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Mizuno M, Hori M, Kodera Y

    International journal of oncology   Vol. 47 ( 5 ) page: 1655-62   2015.11

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    DOI: 10.3892/ijo.2015.3149

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  172. Capecitabine and oxaliplatin combined with bevacizumab are feasible for treating selected Japanese patients at least 75 years of age with metastatic colorectal cancer.

    Munemoto Y, Kanda M, Ishibashi K, Hata T, Kobayashi M, Hasegawa J, Fukunaga M, Takagane A, Otsuji T, Miyake Y, Nagase M, Sakamoto J, Matsuoka M, Oba K, Mishima H

    BMC cancer   Vol. 15   page: 786   2015.10

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    DOI: 10.1186/s12885-015-1712-0

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  173. Genetic and epigenetic aspects of initiation and progression of hepatocellular carcinoma. Reviewed

    Kanda M, Sugimoto H, Kodera Y

    World journal of gastroenterology   Vol. 21 ( 37 ) page: 10584-97   2015.10

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    DOI: 10.3748/wjg.v21.i37.10584

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  174. Updated evidence on adjuvant treatments for gastric cancer. Reviewed

    Kanda M, Kodera Y, Sakamoto J

    Expert review of gastroenterology & hepatology     page: 1-12   2015.9

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    DOI: 10.1586/17474124.2015.1094373

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  175. Adherens junctions associated protein 1 serves as a predictor of recurrence of squamous cell carcinoma of the esophagus. Reviewed

    Tanaka H, Kanda M, Koike M, Iwata N, Shimizu D, Ezaka K, Sueoka S, Tanaka Y, Takami H, Hashimoto R, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Fujiwara M, Kodera Y

    International journal of oncology     2015.9

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    DOI: 10.3892/ijo.2015.3167

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  176. Recent advances in the molecular diagnostics of gastric cancer. Reviewed

    Kanda M, Kodera Y

    World journal of gastroenterology : WJG   Vol. 21 ( 34 ) page: 9838-52   2015.9

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    DOI: 10.3748/wjg.v21.i34.9838

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  177. Inverse Probability of Treatment Weighting Analysis of Upfront Surgery Versus Neoadjuvant Chemoradiotherapy Followed by Surgery for Pancreatic Adenocarcinoma with Arterial Abutment.

    Fujii T, Yamada S, Murotani K, Kanda M, Sugimoto H, Nakao A, Kodera Y

    Medicine   Vol. 94 ( 39 ) page: e1647   2015.9

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    DOI: 10.1097/MD.0000000000001647

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  178. Factors related to occurrence and aggravation of pancreatic fistula after radical gastrectomy for gastric cancer.

    Kobayashi D, Iwata N, Tanaka C, Kanda M, Yamada S, Nakayama G, Fujii T, Koike M, Fujiwara M, Kodera Y

    Journal of surgical oncology   Vol. 112 ( 4 ) page: 381-6   2015.9

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    DOI: 10.1002/jso.24001

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  179. Function and diagnostic value of Anosmin-1 in gastric cancer progression. Reviewed

    Kanda M, Shimizu D, Fujii T, Sueoka S, Tanaka Y, Ezaka K, Takami H, Tanaka H, Hashimoto R, Iwata N, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    International journal of cancer. Journal international du cancer     2015.8

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    DOI: 10.1002/ijc.29803

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  180. Excess Weight Adversely Influences Treatment Length of Postoperative Pancreatic Fistula: A Retrospective Study of 900 Patients.

    Fujii T, Kanda M, Nagai S, Suenaga M, Takami H, Yamada S, Sugimoto H, Nomoto S, Nakao A, Kodera Y

    Pancreas   Vol. 44 ( 6 ) page: 971-6   2015.8

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    DOI: 10.1097/MPA.0000000000000352

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  181. Effectiveness of plasma treatment on gastric cancer cells.

    Torii K, Yamada S, Nakamura K, Tanaka H, Kajiyama H, Tanahashi K, Iwata N, Kanda M, Kobayashi D, Tanaka C, Fujii T, Nakayama G, Koike M, Sugimoto H, Nomoto S, Natsume A, Fujiwara M, Mizuno M, Hori M, Saya H, Kodera Y

    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association   Vol. 18 ( 3 ) page: 635-43   2015.7

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    DOI: 10.1007/s10120-014-0395-6

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  182. Reduced Expression of Adherens Junctions Associated Protein 1 Predicts Recurrence of Hepatocellular Carcinoma After Curative Hepatectomy. Reviewed

    Ezaka K, Kanda M, Sugimoto H, Shimizu D, Oya H, Nomoto S, Sueoka S, Tanaka Y, Takami H, Hashimoto R, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Annals of surgical oncology     2015.6

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    DOI: 10.1245/s10434-015-4695-9

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  183. Postoperative adjuvant chemotherapy with S-1 alters recurrence patterns and prognostic factors among patients with stage II/III gastric cancer: A propensity score matching analysis. Reviewed

    Kanda M, Murotani K, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Surgery     2015.6

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    DOI: 10.1016/j.surg.2015.05.017

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  184. Translational implication of Kallmann syndrome-1 gene expression in hepatocellular carcinoma. Reviewed

    Tanaka Y, Kanda M, Sugimoto H, Shimizu D, Sueoka S, Takami H, Ezaka K, Hashimoto R, Okamura Y, Iwata N, Tanaka C, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y

    International journal of oncology   Vol. 46 ( 6 ) page: 2546-54   2015.6

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    DOI: 10.3892/ijo.2015.2965

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  185. Protein tyrosine kinase 7: a hepatocellular carcinoma-related gene detected by triple-combination array.

    Hishida M, Inokawa Y, Takano N, Nishikawa Y, Iwata N, Kanda M, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Fujiwara M, Kodera Y, Nomoto S

    The Journal of surgical research   Vol. 195 ( 2 ) page: 444-53   2015.5

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    DOI: 10.1016/j.jss.2014.12.045

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  186. Diversity of clinical implication of B-cell translocation gene 1 expression by histopathologic and anatomic subtypes of gastric cancer. Reviewed

    Kanda M, Oya H, Nomoto S, Takami H, Shimizu D, Hashimoto R, Sueoka S, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Digestive diseases and sciences   Vol. 60 ( 5 ) page: 1256-64   2015.5

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    DOI: 10.1007/s10620-014-3477-8

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  187. Dihydropyrimidinase-like 3 is a putative hepatocellular carcinoma tumor suppressor. Reviewed

    Oya H, Kanda M, Sugimoto H, Shimizu D, Takami H, Hibino S, Hashimoto R, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Journal of gastroenterology   Vol. 50 ( 5 ) page: 590-600   2015.5

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    DOI: 10.1007/s00535-014-0993-4

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  188. KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound. Reviewed

    Eshleman JR, Norris AL, Sadakari Y, Debeljak M, Borges M, Harrington C, Lin E, Brant A, Barkley T, Almario JA, Topazian M, Farrell J, Syngal S, Lee JH, Yu J, Hruban RH, Kanda M, Canto MI, Goggins M

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association   Vol. 13 ( 5 ) page: 963-9.e4   2015.5

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    DOI: 10.1016/j.cgh.2014.11.028

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  189. A vascular endothelial growth factor gene polymorphism predicts malignant potential in intraductal papillary mucinous neoplasm.

    Yabusaki N, Yamada S, Shimoyama Y, Fujii T, Kanda M, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Nakao A, Kodera Y

    Pancreas   Vol. 44 ( 4 ) page: 608-14   2015.5

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    DOI: 10.1097/MPA.0000000000000305

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  190. Feeding duodenostomy decreases the incidence of mechanical obstruction after radical esophageal cancer surgery.

    Oya H, Koike M, Iwata N, Kobayashi D, Torii K, Niwa Y, Kanda M, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    World journal of surgery   Vol. 39 ( 5 ) page: 1105-10   2015.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00268-015-2952-5

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  191. CCNJ detected by triple combination array analysis as a tumor-related gene of hepatocellular carcinoma.

    Takano N, Hishida M, Inokawa Y, Hayashi M, Kanda M, Nishikawa Y, Iwata N, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Fujiwara M, Kodera Y, Nomoto S

    International journal of oncology   Vol. 46 ( 5 ) page: 1963-70   2015.5

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    DOI: 10.3892/ijo.2015.2892

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  192. SMAD4 expression predicts local spread and treatment failure in resected pancreatic cancer.

    Yamada S, Fujii T, Shimoyama Y, Kanda M, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Nakao A, Kodera Y

    Pancreas   Vol. 44 ( 4 ) page: 660-4   2015.5

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    DOI: 10.1097/MPA.0000000000000315

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  193. Prognostic impact of expression and methylation status of DENN/MADD domain-containing protein 2D in gastric cancer. Reviewed

    Kanda M, Shimizu D, Nomoto S, Takami H, Hibino S, Oya H, Hashimoto R, Suenaga M, Inokawa Y, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Gastric cancer   Vol. 18 ( 2 ) page: 288-96   2015.4

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    DOI: 10.1007/s10120-014-0372-0

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  194. Vein resections &gt;3 cm during pancreatectomy are associated with poor 1-year patency rates.

    Fujii T, Nakao A, Yamada S, Suenaga M, Hattori M, Takami H, Inokawa Y, Kanda M, Sugimoto H, Nomoto S, Murotani K, Kodera Y

    Surgery   Vol. 157 ( 4 ) page: 708-15   2015.4

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    DOI: 10.1016/j.surg.2014.12.002

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  195. Preoperative internal biliary drainage increases the risk of bile juice infection and pancreatic fistula after pancreatoduodenectomy: a prospective observational study.

    Fujii T, Yamada S, Suenaga M, Kanda M, Takami H, Sugimoto H, Nomoto S, Nakao A, Kodera Y

    Pancreas   Vol. 44 ( 3 ) page: 465-70   2015.4

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    DOI: 10.1097/MPA.0000000000000265

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  196. Suppression of SAMSN1 Expression is Associated with the Malignant Phenotype of Hepatocellular Carcinoma. Reviewed

    Sueoka S, Kanda M, Sugimoto H, Shimizu D, Nomoto S, Oya H, Takami H, Ezaka K, Hashimoto R, Tanaka Y, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Annals of surgical oncology     2015.3

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    DOI: 10.1245/s10434-015-4524-1

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  197. The Expression of Melanoma-Associated Antigen D2 Both in Surgically Resected and Serum Samples Serves as Clinically Relevant Biomarker of Gastric Cancer Progression. Reviewed

    Kanda M, Nomoto S, Oya H, Takami H, Shimizu D, Hibino S, Hashimoto R, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Annals of surgical oncology     2015.3

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    DOI: 10.1245/s10434-015-4457-8

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  198. Aberrant expression of melanoma-associated antigen-D2 serves as a prognostic indicator of hepatocellular carcinoma outcome following curative hepatectomy. Reviewed

    Hashimoto R, Kanda M, Takami H, Shimizu D, Oya H, Hibino S, Okamura Y, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Oncology letters   Vol. 9 ( 3 ) page: 1201-1206   2015.3

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    DOI: 10.3892/ol.2014.2823

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  199. Clinical significance of zinc-finger E-box binding homeobox 1 mRNA levels in peritoneal washing for gastric cancer.

    Yabusaki N, Yamada S, Murai T, Kanda M, Kobayashi D, Tanaka C, Fujii T, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Molecular and clinical oncology   Vol. 3 ( 2 ) page: 435-441   2015.3

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    DOI: 10.3892/mco.2014.462

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  200. Method of bilateral pleural drainage by single Blake drain after esophagectomy.

    Niwa Y, Koike M, Oya H, Iwata N, Kobayashi D, Kanda M, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    World journal of surgery   Vol. 39 ( 3 ) page: 727-31   2015.3

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    DOI: 10.1007/s00268-014-2860-0

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  201. Serosal invasion strongly associated with recurrence after curative hepatic resection of hepatocellular carcinoma: a retrospective study of 214 consecutive cases.

    Sonohara F, Nomoto S, Inokawa Y, Kanda M, Yamada S, Fujii T, Sugimoto H, Kodera Y

    Medicine   Vol. 94 ( 9 ) page: e602   2015.3

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    DOI: 10.1097/MD.0000000000000602

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  202. B‑cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinoma. Reviewed

      Vol. 46 ( 2 ) page: 641-8   2015.2

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    DOI: 10.3892/ijo.2014.2762

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  203. High expression of Janus kinase 2 in background normal liver tissue of resected hepatocellular carcinoma is associated with worse prognosis.

    Sonohara F, Nomoto S, Inokawa Y, Hishida M, Takano N, Kanda M, Nishikawa Y, Fujii T, Koike M, Sugimoto H, Kodera Y

    Oncology reports   Vol. 33 ( 2 ) page: 767-73   2015.2

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    DOI: 10.3892/or.2014.3621

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  204. Adverse prognostic impact of perioperative allogeneic transfusion on patients with stage II/III gastric cancer. Reviewed

    Kanda M, Kobayashi D, Tanaka C, Iwata N, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Nomoto S, Murotani K, Fujiwara M, Kodera Y

    Gastric cancer     2015.1

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    DOI: 10.1007/s10120-014-0456-x

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  205. Significance of the Splenic Vein and Its Branches in Pancreatoduodenectomy with Resection of the Portal Vein System.

    Hattori M, Fujii T, Yamada S, Inokawa Y, Suenaga M, Takami H, Kanda M, Sugimoto H, Nomoto S, Murotani K, Nakao A, Kodera Y

    Digestive surgery   Vol. 32 ( 5 ) page: 382-8   2015

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    DOI: 10.1159/000438797

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  206. Mutant KRAS and GNAS DNA Concentrations in Secretin-Stimulated Pancreatic Fluid Collected from the Pancreatic Duct and the Duodenal Lumen. Reviewed

    Sadakari Y, Kanda M, Maitani K, Borges M, Canto MI, Goggins M

    Clinical and translational gastroenterology   Vol. 5   page: e62   2014.11

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    DOI: 10.1038/ctg.2014.14

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  207. Clinical utility of PDSS2 expression to stratify patients at risk for recurrence of hepatocellular carcinoma. Reviewed

    Kanda M, Sugimoto H, Nomoto S, Oya H, Shimizu D, Takami H, Hashimoto R, Sonohara F, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Fujiwara M, Kodera Y

    International journal of oncology   Vol. 45 ( 5 ) page: 2005-12   2014.11

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    DOI: 10.3892/ijo.2014.2637

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  208. Hepatectomy for hepatocellular carcinoma in patients with hemophilia.

    Inokawa Y, Sugimoto H, Kanda M, Yamada S, Fujii T, Nomoto S, Takeda S, Suzuki N, Matsushita T, Kodera Y

    Journal of hepato-biliary-pancreatic sciences   Vol. 21 ( 11 ) page: 824-8   2014.11

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    DOI: 10.1002/jhbp.142

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  209. Epithelial to mesenchymal transition correlates with tumor budding and predicts prognosis in esophageal squamous cell carcinoma.

    Niwa Y, Yamada S, Koike M, Kanda M, Fujii T, Nakayama G, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    Journal of surgical oncology   Vol. 110 ( 6 ) page: 764-9   2014.11

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    DOI: 10.1002/jso.23694

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  210. Epithelial to mesenchymal transition might be induced via CD44 isoform switching in colorectal cancer.

    Mashita N, Yamada S, Nakayama G, Tanaka C, Iwata N, Kanda M, Kobayashi D, Fujii T, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y

    Journal of surgical oncology   Vol. 110 ( 6 ) page: 745-51   2014.11

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    DOI: 10.1002/jso.23705

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  211. Decreased expression of prenyl diphosphate synthase subunit 2 correlates with reduced survival of patients with gastric cancer. Reviewed

    Kanda M, Nomoto S, Oya H, Hashimoto R, Takami H, Shimizu D, Sonohara F, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Murotani K, Fujiwara M, Kodera Y

    Journal of experimental & clinical cancer research : CR   Vol. 33   page: 88   2014.10

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    DOI: 10.1186/s13046-014-0088-3

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  212. Estimated pancreatic parenchymal remnant volume accurately predicts clinically relevant pancreatic fistula after pancreatoduodenectomy. Reviewed

    Kanda M, Fujii T, Suenaga M, Takami H, Hattori M, Inokawa Y, Yamada S, Nakayama G, Sugimoto H, Koike M, Nomoto S, Kodera Y.

    Surgery   Vol. 156 ( 3 ) page: 601-610   2014.9

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  213. The combination of the serum carbohydrate antigen 19-9 and carcinoembryonic antigen is a simple and accurate predictor of mortality in pancreatic cancer patients. Reviewed

    Kanda M, Fujii T, Takami H, Suenaga M, Inokawa Y, Yamada S, Nakayama G, Sugimoto H, Koike M, Nomoto S, Kodera Y.

    Surgery Today   Vol. 44 ( 9 ) page: 1692-701   2014.9

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  214. Estimated pancreatic parenchymal remnant volume accurately predicts clinically relevant pancreatic fistula after pancreatoduodenectomy. Reviewed

    Kanda M, Fujii T, Suenaga M, Takami H, Hattori M, Inokawa Y, Yamada S, Nakayama G, Sugimoto H, Koike M, Nomoto S, Kodera Y

    Surgery   Vol. 156 ( 3 ) page: 601-10   2014.9

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    DOI: 10.1016/j.surg.2014.04.011

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  215. Combination of the serum carbohydrate antigen 19-9 and carcinoembryonic antigen is a simple and accurate predictor of mortality in pancreatic cancer patients. Reviewed

    Kanda M, Fujii T, Takami H, Suenaga M, Inokawa Y, Yamada S, Nakayama G, Sugimoto H, Koike M, Nomoto S, Kodera Y

    Surgery today   Vol. 44 ( 9 ) page: 1692-701   2014.9

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    DOI: 10.1007/s00595-013-0752-9

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  216. Pattern of first recurrent lesions in pancreatic cancer: hepatic relapse is associated with dismal prognosis and portal vein invasion.

    Suenaga M, Fujii T, Kanda M, Takami H, Okumura N, Inokawa Y, Kobayashi D, Tanaka C, Yamada S, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y

    Hepato-gastroenterology   Vol. 61 ( 134 ) page: 1756-61   2014.9

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  217. Comparison of inflammation-based prognostic scores as predictors of tumor recurrence in patients with hepatocellular carcinoma after curative resection.

    Yamamura K, Sugimoto H, Kanda M, Yamada S, Nomoto S, Nakayama G, Fujii T, Koike M, Fujiwara M, Kodera Y

    Journal of hepato-biliary-pancreatic sciences   Vol. 21 ( 9 ) page: 682-8   2014.9

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    DOI: 10.1002/jhbp.114

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  218. Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer. Reviewed

    Kanda M, Nomoto S, Oya H, Shimizu D, Takami H, Hibino S, Hashimoto R, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Journal of experimental & clinical cancer research : CR   Vol. 33   page: 66   2014.8

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    DOI: 10.1186/s13046-014-0066-9

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  219. Pancreatoduodenectomy with portal vein resection is feasible and potentially beneficial for elderly patients with pancreatic cancer. Reviewed

    Kanda M, Fujii T, Suenaga M, Takami H, Inokawa Y, Yamada S, Kobayashi D, Tanaka C, Sugimoto H, Nomoto S, Fujiwara M, Kodera Y.

    Pancreas   Vol. 43 ( 6 ) page: 951-958   2014.8

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  220. Clinical significance of expression and epigenetic profiling of TUSC1 in gastric cancer. Reviewed

    Kanda M, Shimizu D, Nomoto S, Hibino S, Oya H, Takami H, Kobayashi D, Yamada S, Inokawa Y, Tanaka C, Fujii T, Sugimoto H, Koike M, Fujiwara M, Kodera Y.

    Journal of Surgical Oncology   Vol. 110 ( 2 ) page: 136-144   2014.8

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  221. ovel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy. Reviewed

    Kanda M, Fujii T, Takami H, Suenaga M, Inokawa Y, Yamada S, Kobayashi D, Tanaka C, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y.

    World Journal of Gastroenterology   Vol. 20 ( 26 ) page: 8535-8544   2014.7

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  222. Novel diagnostics for aggravating pancreatic fistulas at the acute phase after pancreatectomy. Reviewed

    Kanda M, Fujii T, Takami H, Suenaga M, Inokawa Y, Yamada S, Kobayashi D, Tanaka C, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Kodera Y

    World journal of gastroenterology : WJG   Vol. 20 ( 26 ) page: 8535-44   2014.7

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    DOI: 10.3748/wjg.v20.i26.8535

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  223. Clinical implication of morphological subtypes in management of intraductal papillary mucinous neoplasm.

    Yamada S, Fujii T, Shimoyama Y, Kanda M, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Nakao A, Kodera Y

    Annals of surgical oncology   Vol. 21 ( 7 ) page: 2444-52   2014.7

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    DOI: 10.1245/s10434-014-3565-1

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  224. Preservation of the pyloric ring confers little benefit in patients undergoing total pancreatectomy.

    Takami H, Fujii T, Kanda M, Suenaga M, Yamamura K, Kodera Y

    World journal of surgery   Vol. 38 ( 7 ) page: 1807-13   2014.7

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    DOI: 10.1007/s00268-014-2469-3

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  225. Modified Blumgart anastomosis for pancreaticojejunostomy: technical improvement in matched historical control study.

    Fujii T, Sugimoto H, Yamada S, Kanda M, Suenaga M, Takami H, Hattori M, Inokawa Y, Nomoto S, Fujiwara M, Kodera Y

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract   Vol. 18 ( 6 ) page: 1108-15   2014.6

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    DOI: 10.1007/s11605-014-2523-3

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  226. Expression analysis of THOP1 in background liver, a prognostic predictive factor in hepatocellular carcinoma, extracted by multiarray analysis.

    Nomoto S, Hishida M, Inokawa Y, Takano N, Kanda M, Nishikawa Y, Fujii T, Koike M, Sugimoto H, Kodera Y

    Annals of surgical oncology   Vol. 21 Suppl 3   page: S443-50   2014.6

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    DOI: 10.1245/s10434-014-3581-1

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  227. Prognostic impact of expression and methylation status of DENN/MADD domain-containing protein 2D in gastric cancer. Gastric Cancer. Reviewed

    Kanda M, Shimizu D, Nomoto S, Takami H, Hibino S, Oya H, Hashimoto R, Suenaga M, Inokawa Y, Kobayashi D, Tanaka C, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y.

    Gastric Cancer     page: [Epub ahead of print]   2014.4

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  228. The impact of dose/time modification in irinotecan- and oxaliplatin-based chemotherapies on outcomes in metastatic colorectal cancer.

    Nakayama G, Tanaka C, Uehara K, Mashita N, Hayashi N, Kobayashi D, Kanda M, Yamada S, Fujii T, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Ando Y, Kodera Y

    Cancer chemotherapy and pharmacology   Vol. 73 ( 4 ) page: 847-55   2014.4

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    DOI: 10.1007/s00280-014-2416-x

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  229. Identification of intragenic methylation in the TUSC1 gene as a novel prognostic marker of hepatocellular carcinoma. Reviewed

    Shimizu D, Kanda M, Nomoto S, Oya H, Takami H, Hibino S, Suenaga M, Inokawa Y, Hishida M, Takano N, Nishikawa Y, Yamada S, Fujii T, Nakayama G, Sugimoto H, Koike M, Fujiwara M, Kodera Y

    Oncology reports   Vol. 31 ( 3 ) page: 1305-13   2014.3

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    DOI: 10.3892/or.2013.2939

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  230. Identification of the collagen type 1 α 1 gene (COL1A1) as a candidate survival-related factor associated with hepatocellular carcinoma.

      Vol. 14   page: 108   2014.2

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    DOI: 10.1186/1471-2407-14-108

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  231. Reduced expression of DENND2D through promoter hypermethylation is an adverse prognostic factor in squamous cell carcinoma of the esophagus. Reviewed

    Hibino S, Kanda M, Oya H, Takami H, Shimizu D, Nomoto S, Hishida M, Niwa Y, Koike M, Yamada S, Nishikawa Y, Asai M, Nakayama G, Fujii T, Sugimoto H, Fujiwara M, Kodera Y

    Oncology reports   Vol. 31 ( 2 ) page: 693-700   2014.2

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    DOI: 10.3892/or.2013.2901

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  232. Combination treatment of human pancreatic cancer xenograft models with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib and oncolytic herpes simplex virus HF10.

    Yamamura K, Kasuya H, Sahin TT, Tan G, Hotta Y, Tsurumaru N, Fukuda S, Kanda M, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Tanaka M, Kodera Y

    Annals of surgical oncology   Vol. 21 ( 2 ) page: 691-8   2014.2

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    DOI: 10.1245/s10434-013-3329-3

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  233. Downregulation of DENND2D by promoter hypermethylation is associated with early recurrence of hepatocellular carcinoma. Reviewed

    Kanda M, Nomoto S, Oya H, Takami H, Hibino S, Hishida M, Suenaga M, Yamada S, Inokawa Y, Nishikawa Y, Asai M, Fujii T, Sugimoto H, Kodera Y

    International journal of oncology   Vol. 44 ( 1 ) page: 44-52   2014.1

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    DOI: 10.3892/ijo.2013.2165

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  234. B-cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinoma. Reviewed

    Kanda M, Sugimoto H, Nomoto S, Oya H, Hibino S, Shimizu D, Takami H, Hashimoto R, Okamura Y, Yamada S, Fujii T, Nakayama G, Koike M, Fujiwara M, Kodera Y.

    International Journal of Oncology     page: (in press)   2014

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  235. A functional polymorphism in the epidermal growth factor gene predicts hepatocellular carcinoma risk in Japanese hepatitis C patients.

    Suenaga M, Yamada S, Fujii T, Fuchs BC, Okumura N, Kanda M, Kobayashi D, Tanaka C, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Takeda S, Hayashi K, Tanabe KK, Goto H, Kodera Y

    OncoTargets and therapy   Vol. 6   page: 1805-12   2013.12

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    DOI: 10.2147/OTT.S53625

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  236. Evaluation of MAGE-D4 expression in hepatocellular carcinoma in Japanese patients. Reviewed

    Takami H, Kanda M, Oya H, Hibino S, Sugimoto H, Suenaga M, Yamada S, Nishikawa Y, Asai M, Fujii T, Nomoto S, Kodera Y

    Journal of surgical oncology   Vol. 108 ( 8 ) page: 557-62   2013.12

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    DOI: 10.1002/jso.23440

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  237. [Recurrent acute pancreatitis due to arteriovenous malformation of the pancreas].

    Suenaga M, Fujii T, Kanda M, Yamada S, Okumura N, Takeda S, Kodera Y

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   Vol. 110 ( 11 ) page: 1983-8   2013.11

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  238. Dynamin 3: a new candidate tumor suppressor gene in hepatocellular carcinoma detected by triple combination array analysis.

    Inokawa Y, Nomoto S, Hishida M, Hayashi M, Kanda M, Nishikawa Y, Takeda S, Fujiwara M, Koike M, Sugimoto H, Fujii T, Nakayama G, Yamada S, Tanaka C, Kobayashi D, Kodera Y

    OncoTargets and therapy   Vol. 6   page: 1417-24   2013.10

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    DOI: 10.2147/OTT.S51913

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  239. Detection of doublecortin domain-containing 2 (DCDC2), a new candidate tumor suppressor gene of hepatocellular carcinoma, by triple combination array analysis.

    Inokawa Y, Nomoto S, Hishida M, Hayashi M, Kanda M, Nishikawa Y, Takeda S, Sugimoto H, Fujii T, Yamada S, Kodera Y

    Journal of experimental & clinical cancer research : CR   Vol. 32   page: 65   2013.9

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    DOI: 10.1186/1756-9966-32-65

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  240. Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts. Reviewed

    Kanda M, Knight S, Topazian M, Syngal S, Farrell J, Lee J, Kamel I, Lennon AM, Borges M, Young A, Fujiwara S, Seike J, Eshleman J, Hruban RH, Canto MI, Goggins M

    Gut   Vol. 62 ( 7 ) page: 1024-33   2013.7

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    DOI: 10.1136/gutjnl-2012-302823

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  241. Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis.

    Hishida M, Nomoto S, Inokawa Y, Hayashi M, Kanda M, Okamura Y, Nishikawa Y, Tanaka C, Kobayashi D, Yamada S, Nakayama G, Fujii T, Sugimoto H, Koike M, Fujiwara M, Takeda S, Kodera Y

    International journal of oncology   Vol. 43 ( 1 ) page: 88-94   2013.7

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    DOI: 10.3892/ijo.2013.1951

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  242. Mutant TP53 in duodenal samples of pancreatic juice from patients with pancreatic cancer or high-grade dysplasia. Reviewed

    Kanda M, Sadakari Y, Borges M, Topazian M, Farrell J, Syngal S, Lee J, Kamel I, Lennon AM, Knight S, Fujiwara S, Hruban RH, Canto MI, Goggins M

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association   Vol. 11 ( 6 ) page: 719-30.e5   2013.6

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    DOI: 10.1016/j.cgh.2012.11.016

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  243. Genome-wide somatic copy number alterations in low-grade PanINs and IPMNs from individuals with a family history of pancreatic cancer. Reviewed

    Hong SM, Vincent A, Kanda M, Leclerc J, Omura N, Borges M, Klein AP, Canto MI, Hruban RH, Goggins M

    Clinical cancer research : an official journal of the American Association for Cancer Research   Vol. 18 ( 16 ) page: 4303-12   2012.8

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    DOI: 10.1158/1078-0432.CCR-12-1075

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  244. Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. Reviewed

    Kanda M, Matthaei H, Wu J, Hong SM, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B, Goggins M

    Gastroenterology   Vol. 142 ( 4 ) page: 730-733.e9   2012.4

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    DOI: 10.1053/j.gastro.2011.12.042

    PubMed

  245. Preservation of the pyloric ring has little value in surgery for pancreatic head cancer: a comparative study comparing three surgical procedures.

    Fujii T, Kanda M, Kodera Y, Nagai S, Sahin TT, Hayashi M, Kanzaki A, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Annals of surgical oncology   Vol. 19 ( 1 ) page: 176-83   2012.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-011-1901-2

    PubMed

  246. Comparison of pancreatic head resection with segmental duodenectomy and pylorus-preserving pancreatoduodenectomy for benign and low-grade malignant neoplasms of the pancreatic head.

    Fujii T, Kanda M, Kodera Y, Nagai S, Sahin TT, Kanzaki A, Yamada S, Sugimoto H, Nomoto S, Morita S, Takeda S, Nakao A

    Pancreas   Vol. 40 ( 8 ) page: 1258-63   2011.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e318220b1c0

    PubMed

  247. Prognostic implications of lymph node metastases in carcinoma of the body and tail of the pancreas.

    Sahin TT, Fujii T, Kanda M, Nagai S, Kodera Y, Kanzaki A, Yamamura K, Sugimoto H, Kasuya H, Nomoto S, Takeda S, Morita S, Nakao A

    Pancreas   Vol. 40 ( 7 ) page: 1029-33   2011.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e3182207893

    PubMed

  248. Pattern of lymph node metastasis spread in pancreatic cancer. Reviewed

    Kanda M, Fujii T, Nagai S, Kodera Y, Kanzaki A, Sahin TT, Hayashi M, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Pancreas   Vol. 40 ( 6 ) page: 951-5   2011.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e3182148342

    PubMed

  249. Promoter hypermethylation of fibulin 1 gene is associated with tumor progression in hepatocellular carcinoma. Reviewed

    Kanda M, Nomoto S, Okamura Y, Hayashi M, Hishida M, Fujii T, Nishikawa Y, Sugimoto H, Takeda S, Nakao A

    Molecular carcinogenesis   Vol. 50 ( 8 ) page: 571-9   2011.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/mc.20735

    PubMed

  250. Recurrence pattern and prognosis of pancreatic cancer after pancreatic fistula.

    Nagai S, Fujii T, Kodera Y, Kanda M, Sahin TT, Kanzaki A, Hayashi M, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Annals of surgical oncology   Vol. 18 ( 8 ) page: 2329-37   2011.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-011-1604-8

    PubMed

  251. Nutritional predictors of postoperative outcome in pancreatic cancer. Reviewed

    Kanda M, Fujii T, Kodera Y, Nagai S, Takeda S, Nakao A.

    British Journal of Surgery   Vol. 98 ( 2 ) page: 268-274   2011.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  252. Reduced expression of reelin (RELN) gene is associated with high recurrence rate of hepatocellular carcinoma.

    Okamura Y, Nomoto S, Kanda M, Hayashi M, Nishikawa Y, Fujii T, Sugimoto H, Takeda S, Nakao A

    Annals of surgical oncology   Vol. 18 ( 2 ) page: 572-9   2011.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-010-1273-z

    PubMed

  253. Impact of operative blood loss on survival in invasive ductal adenocarcinoma of the pancreas.

    Nagai S, Fujii T, Kodera Y, Kanda M, Sahin TT, Kanzaki A, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Pancreas   Vol. 40 ( 1 ) page: 3-9   2011.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e3181f7147a

    PubMed

  254. Prognostic implications of intraoperative radiotherapy for unresectable pancreatic cancer.

    Nagai S, Fujii T, Kodera Y, Kanda M, Sahin TT, Kanzaki A, Yamada S, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakao A

    Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]   Vol. 11 ( 1 ) page: 68-75   2011

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000324682

    PubMed

  255. Prognostic impact of pancreatic margin status in the intraductal papillary mucinous neoplasms of the pancreas.

    Fujii T, Kato K, Kodera Y, Kanda M, Nagai S, Yamada S, Kanzaki A, Sugimoto H, Nomoto S, Takeda S, Morita S, Nakamura S, Nakao A

    Surgery   Vol. 148 ( 2 ) page: 285-90   2010.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.surg.2010.03.013

    PubMed

  256. Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array.

    Okamura Y, Nomoto S, Kanda M, Li Q, Nishikawa Y, Sugimoto H, Kanazumi N, Takeda S, Nakao A

    Cancer letters   Vol. 289 ( 2 ) page: 170-7   2010.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.canlet.2009.08.013

    PubMed

  257. Operative treatment of pancreatic ductal adenocarcinoma with extensive portal venous tumor embolism. Reviewed

    Kanda M, Takeda S, Yamada S, Fujii T, Sugimoto H, Kanazumi N, Nomoto S, Nakao A.

    Pancreas   Vol. 39 ( 2 ) page: 268-269   2010.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  258. Operative treatment of thrombotic occlusion of the portal vein immediately after pancreatectomy with portal vein resection. Reviewed

    Kanda M, Takeda S, Yamada S, Fujii T, Sugimoto H, Kanazumi N, Nomoto S, Nakao A.

    Pancreas   Vol. 39 ( 2 ) page: 265-266   2010.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  259. Operative treatment of thrombotic occlusion of the portal vein immediately after pancreatectomy with portal vein resection. Reviewed

    Kanda M, Takeda S, Yamada S, Fujii T, Sugimoto H, Kanazumi N, Nomoto S, Nakao A

    Pancreas   Vol. 39 ( 2 ) page: 265-6   2010.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/MPA.0b013e3181baef66

    PubMed

  260. Invasion of the splenic artery is a crucial prognostic factor in carcinoma of the body and tail of the pancreas. Reviewed

    Kanda M, Fujii T, Sahin TT, Kanzaki A, Nagai S, Yamada S, Sugimoto H, Nomoto S, Takeda S, Kodera Y, Morita S, Nakao A

    Annals of surgery   Vol. 251 ( 3 ) page: 483-7   2010.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1097/SLA.0b013e3181cf9171

    PubMed

  261. Epidermal growth factor-containing fibulin-like extracellular matrix protein 1, EFEMP1, a novel tumor-suppressor gene detected in hepatocellular carcinoma using double combination array analysis.

    Nomoto S, Kanda M, Okamura Y, Nishikawa Y, Qiyong L, Fujii T, Sugimoto H, Takeda S, Nakao A

    Annals of surgical oncology   Vol. 17 ( 3 ) page: 923-32   2010.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1245/s10434-009-0790-0

    PubMed

  262. Detection of metallothionein 1G as a methylated tumor suppressor gene in human hepatocellular carcinoma using a novel method of double combination array analysis. Reviewed

    Kanda M, Nomoto S, Okamura Y, Nishikawa Y, Sugimoto H, Kanazumi N, Takeda S, Nakao A

    International journal of oncology   Vol. 35 ( 3 ) page: 477-83   2009.9

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    PubMed

  263. Correlations of the expression of vascular endothelial growth factor B and its isoforms in hepatocellular carcinoma with clinico-pathological parameters. Reviewed

    Kanda M, Nomoto S, Nishikawa Y, Sugimoto H, Kanazumi N, Takeda S, Nakao A

    Journal of surgical oncology   Vol. 98 ( 3 ) page: 190-6   2008.9

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jso.21095

    PubMed

▼display all

Presentations 24

  1. Expression and methylation status of DENND2D in gastric cancer 胃癌における膜輸送蛋白のDENND2D発現の関する検討

    神田光郎,岩田直樹,小林大介,田中千恵,山田 豪,中山吾郎,藤井 努,杉本博行,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    第25回日本消化器癌発生学会総会 (第8回国際消化器癌発生会議) 

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    Event date: 2014.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:福岡   Country:Japan  

  2. 肝細胞癌におけるB-cell translocation gene 1発現の意義の検討

    神田光郎,大屋久晴,野本周嗣,日比野壮貴,清水 大,高見秀樹,橋本良二,岡村行泰*,岩田直樹,田中千恵,小林大介,山田 豪,藤井 努,中山吾郎,杉本博行,小池聖彦,藤原道隆,小寺泰弘(静岡がんセンター*)

    JDDW2014 第22回日本消化器関連学会週間(第56回日本消化器病学会大会、第88回日本消化器内視鏡学会総会、第18回日本肝臓学会大会、第12回日本消化器外科学会大会) 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸   Country:Japan  

  3. B-cell translocation gene 1 serves as a novel prognostic indicator of hepatocellular carcinoma. International conference

    Mitsuro Kanda, Dai Shimizu, Hiroyuki Sugimoto, Hisaharu Oya, Soki Hibino, Hideki Takami, Ryoji Hashimoto, Yukiyasu Okamura, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Yasuhiro Kodera

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    Event date: 2014.9

    Language:English   Presentation type:Poster presentation  

    Country:Spain  

  4. 胃癌の部位・形態別subtypeにおける,Melanoma-associated antigen D2発現の臨床的意義の検討

    神田光郎,小林大介,田中千恵,山田 豪,藤井 努,中山吾郎,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    第69回日本消化器外科学会総会 

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    Event date: 2014.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:郡山   Country:Japan  

  5. セクレチン負荷十二指腸液中GNAS遺伝子変異検出の膵嚢胞性病変スクリーニングへの応用

    神田光郎,藤井 努,山田 豪,杉本博行,野本周嗣,藤原道隆,小寺泰弘,Michael Goggins* (Johns Hopkins Medical Institute*)

    第45回日本膵臓学会大会 

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    Event date: 2014.7

    Language:Japanese  

    Venue:小倉   Country:Japan  

  6. 術前CT volumetryにおける残膵実質体積の膵頭十二指腸切除術後膵瘻発生予測能の検討 Estimated Pancreatic Parenchymal Remnant Volume Accurately Predicts Clinically Relevant Pancreatic Fistula after Pancreatoduodenectomy

    神田光郎,藤井 努,山田 豪,末永雅也,高見秀樹,杉本博行,野本周嗣,小寺泰弘 Mitsuro Kanda, Tsutomu Fujii, Suguru Yamada, Masaya Suenaga, Hideki Takami, Hiroyuki Sugimoto, Shuji Nomoto, Yasuhiro Kodera

    第26回日本肝胆膵外科学会・学術集会 

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    Event date: 2014.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:和歌山   Country:Japan  

  7. Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

    Mitsuro Kanda, Tsutomu Fujii, Suguru Yamada, Naoki Iwata, Daisuke Kobayashi, Chie Tanaka, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Yasuhiro Kodera, Michael Goggins*(Department of Pathology, Johns Hopkins University*)

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    Event date: 2014.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  8. 当教室における膵神経内分泌腫瘍(PNET)切除例の臨床病理学的検討からのNCCNガイドラインの検証

    神田光郎,藤井 努,山田 豪,岩田直樹,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    第114回日本外科学会定期学術集会 

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    Event date: 2014.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  9. 胃癌における膜輸送蛋白DENND2D発現と予後に関する検討

    神田光郎,岩田直樹,小林大介,田中千恵,山田 豪,中山吾郎,藤井 努,杉本博行,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    第47回制癌剤適応研究会 

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    Event date: 2014.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  10. Overexpression of melanoma-associated antigen D4 as an independent prognostic factor in squamous cell carcinoma of the esophagus. International conference

    Mitsuro Kanda, Hisaharu Oya, Soki Hibino, Hideki Takami, Dai Shimizu, Masahiko Koike, Shuji Nomoto, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Michitaka Fujiwara, Yasuhiro Kodera

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    Event date: 2014.1

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  11. Blumgart変法縫合による空腸漿膜パッチを用いた尾側膵切除後膵瘻防止の試み

    神田光郎,藤井努,山田豪,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    第75回日本臨床外科学会総会 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋   Country:Japan  

  12. 膵癌予後予測因子としての術前血清腫瘍マーカーの検討

    神田光郎,藤井努,高見秀樹,末永雅也,山田豪,田中千恵,小林大介,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,小寺泰弘

    JDDW 2013 第21回日本消化器関連学会週間 (第11回日本消化器外科学会大会・第55回日本消化器病学会大会・第86回日本消化器内視鏡学会総会・第17回日本肝臓学会大会) 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  13. Neoadjuvant chemotherapy with S-1 in patients with borderline resectable pancreatic cancer with involvement of the major vessels. International conference

    Mitsuro Kanda, Tsutomu Fujii, Soki Hibino, Masaya Suenaga, Suguru Yamada, Norio Okumura, Daisuke Kobayashi, Chie Tanaka, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Yasuhiro Kodera

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    Event date: 2013.9

    Language:English   Presentation type:Poster presentation  

    Country:China  

  14. Blumgart変法縫合による空腸漿膜パッチを用いた尾側膵切除後膵瘻防止の試み

    神田光郎,藤井 努,山田 豪,末永雅也,高見秀樹,丹羽由紀子,服部正嗣,杉本博行,野本周嗣,小寺泰弘

    第40回日本膵切研究会 

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    Event date: 2013.8

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:高松   Country:Japan  

  15. Combination of Preoperative Serum CEA and CA19-9 is a Simple and Prominent Predictor in Pancreatic Cancer. International conference

    Mitsuro Kanda, Tsutomu Fujii, Masaya Suenaga, Hideki Takami, Suguru Yamada, Daisuke Kobayashi, Chie Tanaka, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Shin Takeda, Yasuhiro Kodera

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    Event date: 2013.8

    Language:English   Presentation type:Poster presentation  

    Country:Serbia  

  16. セクレチン負荷十二指腸液中TP53変異の,膵癌・高度異形病変診断における有用性の検討

    神田光郎,藤井努,山田豪,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,竹田伸,小寺泰弘,Michael Goggins* (*Department of Pathology, Johns Hopkins Medical Institutions)

    第44回日本膵臓学会大会 

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    Event date: 2013.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台   Country:Japan  

  17. 混合型IPMNの由来別細分類の臨床的意義と治療方針の検討

    神田光郎,藤井努,山田豪,末永雅也,杉本博行,小池聖彦,野本周嗣,藤原道隆,竹田伸,小寺泰弘

    第68回日本消化器外科学会総会 

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    Event date: 2013.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:宮崎   Country:Japan  

  18. PANCREATODUODENECTOMY WITH PORTAL VEIN RESECTION IS FEASIBLE AND BENEFICIAL FOR ELDERLY PATIENTS WITH PANCREATIC CANCER. International conference

    Mitsuro Kanda, Tsutomu Fujii, Hideki Takami, Hisaharu Ohya, Masaya Suenaga, Suguru Yamada, Daisuke Kobayashi, Chie Tanaka, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Yasuhiro Kodera

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    Event date: 2013.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Spain  

  19. 膵嚢胞性病変スクリーニングにおける,セクレチン負荷十二指腸採取液中GNAS遺伝子変異検出の有用性

    神田光郎,藤井努,山田豪,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,竹田伸,小寺泰弘,Michael Goggins* (ジョンズホプキンス大学 病理部*)

    第25回日本肝胆膵外科学会・学術集会 

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    Event date: 2013.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:宇都宮   Country:Japan  

  20. 膵上皮内腫瘍性病変の初期発生段階における体細胞変異の検討

    神田光郎,藤井努,山田豪,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,竹田伸,小寺泰弘,Goggins Michael* (Johns Hopkins大学病理学*)

    第113回日本外科学会定期学術集会 

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    Event date: 2013.4

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡   Country:Japan  

  21. 膵癌における術前栄養免疫学的予後予測因子の検討

    神田光郎,藤井努,長井俊志,山田豪,小林大介,田中千恵,中山吾郎,杉本博行,小池聖彦,野本周嗣,藤原道隆,竹田伸,中尾昭公*,小寺泰弘 (名古屋セントラル病院*)

    第99回日本消化器病学会総会 

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    Event date: 2013.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:鹿児島   Country:Japan  

  22. 膵頭部癌に対するMesenteric approachによる上腸間膜動脈周囲リンパ節・神経叢郭清

    神田光郎,藤井努,神崎章之,長井俊志,杉本博行,粕谷英樹,野本周嗣,竹田伸,中尾昭公

    第65回日本消化器外科学会総会 

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    Event date: 2010.7

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:下関   Country:Japan  

  23. Non-touch isolated pancreatoduodenectomy with a mesenteric approach for pancreatic head cancer. International conference

    Mitsuro Kanda, Akimasa Nakao, Tsutomu Fujii, Shunji Nagai, Takashi Sugae, Masamichi Hayashi, Akiyuki Kanzaki, Yukiyasu Okamura, Suguru Yamada, Hiroyuki Sugimoto, Shuji Nomoto, Shin Takeda

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    Event date: 2010.7

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:Japan  

  24. 肝細胞癌におけるFibulin-1発現と、その調節機序に関する検討

    神田光郎,野本周嗣,岡村行泰,林真路,藤井努,杉本博行,粕谷英樹,竹田伸,中尾昭公

    第110回日本外科学会定期学術集会 

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    Event date: 2010.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

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KAKENHI (Grants-in-Aid for Scientific Research) 10

  1. Development of amido-bridged nucleic acid-modified antisense oligonucleotides to treat gastrointestinal malignancies

    Grant number:20K21629  2020.7 - 2022.3

    Grant-in-Aid for Challenging Research (Exploratory)

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    Authorship:Principal investigator 

    Grant amount:\6370000 ( Direct Cost: \4900000 、 Indirect Cost:\1470000 )

  2. Development of monoclonal antibody targeting CHRNB2 to treat gastric cancer

    Grant number:20H03750  2020.4 - 2024.3

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    Authorship:Principal investigator 

    Grant amount:\17550000 ( Direct Cost: \13500000 、 Indirect Cost:\4050000 )

  3. マルチオミクス解析による胃癌周術期化学療法の奏効度予測バイオマーカーの探索的研究

    Grant number:19K22653  2019.6 - 2021.3

    挑戦的研究(萌芽)

    小寺 泰弘

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    Authorship:Coinvestigator(s) 

    JCOG1509はcStage III 胃癌を対象に、S-1/オキサリプラチン併用療法による術前補助化学療法を加えた周術期化学療法の優越性を検証するランダム化比較第III相試験である。その附随研究として主に術前SOX療法の効果予測因子を同定するためのバイオマーカー研究が提案され、すでに試料収集が開始されている。本研究では、このバイオマーカー研究のpilot研究として、術前化学療法を施行した進行胃癌を対象に【1】JCOG1509附随研究で解析対象とするバイオマーカー候補分子の同定のためのマルチオミクス解析を行うことと、【2】術前生検検体からの癌パネル解析が実施可能かを確認する。
    術後補助化学療法が確立された今も、Stage IIIA、IIIB(胃癌取扱い規約第13版)胃癌の5年生存割合がそれぞれ67%、50%と依然として予後不良であり、更なる治療開発が求められている。術前化学療法は、術前に施行するため化学療法のコンプライアンスが良い、微小転移に対して早期から化学療法が行える、などの理由から、予後不良な進行胃癌に対して有効性が期待されており、JCOG1509はStage III胃癌に対する術前SOX療法の上乗せ効果を検証する第3相試験であり、現在症例登録中である。
    胃癌に対する化学療法の効果予測因子を同定することは、個々人に応じたテーラーメイド治療を確立していく上で大きな意義がある。そこで主として術前SOX療法の効果予測バイオマーカー同定を目的としたJCOG1509附随研究を立案し、本体研究に並行して試料のバンキングを開始した。将来の試料解析研究では、治療前血液検体を対象とした血漿中タンパク/microRNAの解析、主に術前生検組織FFPE検体を対象とした癌パネル解析、手術標本から得る凍結組織およびFFPE検体を対象に組織中タンパク/microRNAの解析を包括的に行うことで術前SOX療法の奏効度と相関する遺伝子学的バイオマーカーを同定する。本研究の目的は、将来の試料解析研究の意義を最大限とし胃癌診療を飛躍的に発展させるために、血漿中タンパク/microRNA解析における独自候補マーカーの選定と、生検検体での癌パネル解析の実施可能性を検討することである。本年度は、研究計画どおりに血漿検体でのプロテオーム解析を完了し、術前生検検体からの癌パネル解析が実施可能かについての事前検討を順調に進めている。
    適格症例の血漿検体、術前生検検体、手術検体からの凍結組織、手術標本FFPE検体を収集し、解析に用いた。血液検体は非侵襲的かつ反復して採取可能であり、これを用いた治療前の効果予測バイオマーカーが同定されることが理想的である。JCOG1509附随研究で解析対象とする血液中バイオマーカー候補タンパクを探索するため、名古屋大学医学部附属病院で術前FU系+プラチナ系化学療法を施行した胃癌のうち、病理学的奏効度を基準に術前化学療法著効例4例と無効例4例から得た治療前の血漿検体を対象にプロテオーム解析を行った。これにより9つの化学療法抵抗性マーカー候補タンパクを抽出した。次世代シークエンサーを用いた遺伝子変異検査CANCERPLEX(デンカ社)は、厳選された435遺伝子のゲノム情報を解析する癌パネルであり、マイクロサテライト不安定性やTumor mutation burdenも解析可能である。患者固有の胃癌ゲノムの状態を評価するために理想的な検体は治療前内視鏡的生検によって得られる癌組織であるが、FFPE保存によるDNA損傷や検体量不足がCANCERPLEX実施において不利な要素となりうる。そこで、内視鏡下生検で得た胃癌組織のFFPE検体を対象にCANCERPLEXの実施に適するDNAの抽出が可能であることを確認する事前検討を実施している。すでに予定の50検体のうち39検体の解析を完了した。
    引き続き、予定に沿った研究計画を遂行する。治療前血漿検体を対象にしたmicroRNA-sequencing:microRNAは癌由来の異常を比較的安定的に循環血液中に反映するとされ、血液中バイオマーカー解析の標的に適している。名古屋大学医学部附属病院で術前FU系+プラチナ系化学療法を施行した胃癌のうち、病理学的奏効度を基準に術前化学療法著効例4例と無効例4例から得た治療前の血漿検体を対象にmicroRNA array解析を行い、術前化学療法奏効度に相関するmicroRNAを抽出する。内視鏡下生検で得た胃癌組織のFFPE検体を対象にしたがんパネル解析CANCERPLEXを予定の50検体まで実施し、生検検体から得られるDNAでの実施性を分析する。同時に、得られたゲノムデータから術前化学療法の耐性に影響しうる遺伝子異常を探索する。治療前の血漿を用いた術前化学療法の効果予測バイオマーカー探索と同じ対象の切除胃癌組織中で、候補バイオマーカーの組織中発現度を免疫組織化学染色法や定量的PCR法で調べる。これにより、それらが腫瘍組織から発生しているかについての知見を得る。

  4. 食道癌に対する新たな抗体医薬とコンパニオン診断技術の開発研究

    Grant number:19K09140  2019.4 - 2022.3

    小池 聖彦

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    多様な進展経路を持つ食道癌は男女ともに癌死亡者数が増加しており、その克服は重要な課題である。食道癌の治療成績を改善するには、病態解明と分子標的治療薬開発につながる新規関連分子の同定が望まれる。本研究では、食道扁平上皮癌の細胞株と組織マイクロアレイで高頻度に発現亢進するレセプター分子を探索し同定したレセプターNに着目し、治療の奏効度を予測するコンパニオン診断法の確立と並行して研究を進める。本研究計画の目的は食道癌におけるレセプターNの機能を明らかにし、これを標的とした創薬ならびに診断法の開発に繋げることである。
    食道癌は多様な進展経路を持つ予後不良な疾患であるが、本邦において男女ともに癌死亡者数が増加しており、その克服は重要な課題である。切除不能・再発食道癌は言うに及ばず、根治切除後も高頻度に再発をきたし不良な転帰をたどることが臨床上の大きな問題となっており、治療成績の改善には抗腫瘍薬の開発が不可欠である。食道癌は消化管通過障害を来しやすく安定した内服が難しいこと、食道切除術は非常に侵襲度が大きく術後QOLも低下しやすいことから、化学療法のコンプライアンスが得られにくい。近年は術前治療に重きを置いた殺細胞性抗腫瘍薬を併用したレジメン開発が試みられてきたが、有害事象が強く、効果も限定的と言わざるを得ない。そこで治療の選択肢を拡大させうる分子標的治療薬の開発が望まれている。我々は、既存の分子標的治療薬とは全く異なる標的としてneuronal pentraxin receptor (NPTXR)を同定し、その食道癌における機能を調べることでメカニズムを明らかとするデータを得つつ、特異的抗体医薬開発の糸口をつかむことを本研究の目的とした。同時に、個別化治療の実現に向けて重要な、奏効度を事前に予測しうるコンパニオン診断法開発に向けてのデータ構築を目指す。まず、shRNAを用いた安定的NPTXRノックダウン食道扁平上皮癌細胞株を樹立し、機能解析を進めている。さらに、抗原性・親水性予測に基づいて抗NTPXR抗体の合成を完了している。研究計画にもとづいて、食道扁平上皮癌細胞におけるNPTXRの機能解析、抗腫瘍剤感受性への影響、癌関連主要pathwayへの干渉、抗NPTXR抗体の食道癌全身転移モデル治療効果の評価、コンパニオン診断薬開発のための臨床検体中NPTXR発現解析を進めていく。
    研究計画通りに、NPTXRの機能解析を進めた。shRNAによる安定的ノックダウン株を用いた癌細胞機能の変化を評価したところ、ノックダウン株では親株と比較して細胞増殖能の低下、アポトーシス細胞比の増加、ミトコンドリア膜電位脱分極増加が認められた。さらに癌の転移進展に重要な浸潤能、遊走能、接着能のいずれもNPTXRノックダウンにより抑制されていた。in vivo実験としてマウス皮下腫瘍モデルによる解析を行ったところ、ノックダウン株では造腫瘍能が有意に低下していた。NPTXRの発現ベクターによる強制発現では、明らかな細胞形質の変化を認めなかった。
    引き続き、予定に沿った研究計画を遂行する。抗腫瘍剤感受性への影響を調べるため、親株と安定的NPTXRノックダウン株の間で食道癌のkey drugである5-FUとCDDPの感受性をWST-8法で比較する。NPTXRの悪性腫瘍における役割には未知の部分が大きく、どのようなsignaling pathwayとの干渉を有するのかを知ることは、その特性を理解するために重要である。Antibody arrayを用いて親株と安定的NPTXRノックダウン株における細胞内signaling pathwayのリン酸化について網羅的に比較し、干渉が示唆された経路についてWestern blotting法により追加・検証解析を行う。

  5. 介入による消化器癌周術期高齢者機能の改善と機能低下に影響するバイオマーカー探索

    Grant number:17K01841  2017.4 - 2021.3

    田中 千恵

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    一昨年の解析結果をまとめると、胃癌に対する胃切除を施行した症例において、自立度、錯乱、認知機能は術前の平均スコアと比較して、退院時の平均スコアのみでなく術後6ヶ月もスコアは低下していなかった。さらに退院時に自立度が低下した症例を対象として低下の予測因子を調査したところ、年齢、性別、胃全摘術、せん妄は関連を認めなかった。しかし、術後合併症の有無(p=0.0326)が自立度低下の予測因子としてあげられた。術前と比較した退院時の認知機能低下は40例中7例(18例)に認められた。
    本研究においてMMSEやCDR-Jといった認知機能の評価は専門医である老年科医師により行われている。現実問題として、これらの評価を周術期に外科医が行うことは困難である上に、専門医による認知機能の評価がどの病院でも常時可能であるとは言えない。我々は認知機能低下症例におけるバイオマーカーを含めた予測因子の探索を行った。
    まずは術前と比較して退院時にMMSEスコアが低下した症例を対象に、臨床病理学的な予測因子の有無を調査したところ、術後せん妄を認めた症例(p=0.1890)、術後在院日数が本研究の平均値である19日を超える症例(p=0.0751)、Clavien-Dindo分類II以上の術後合併症を発症した症例(p=0.0498)であった。以上より、術後合併症を発生した症例はMMSEスコアが有意に低下していたことがわかった。術前IL-6・アディポネクチン・レジスチンの値と術後MMSE低下に明らかな関連は認めなかった。術後CDR-Jスコアの悪化と上記の各因子との間に関連は認めなかった。
    以上より、認知機能の低下と関連するバイオマーカーは見いだせていないが、術後合併症の発生は、自立度のみでなく認知機能の低下に影響する可能性があると考えられた。
    症例集積に時間を要した。しかし、昨年度で高齢者機能評価の測定とバイオマーカー測定は概ね終了した。今後は成果報告を行う。
    成果報告を行うために1年延長した。
    今後は学会、英語論文での成果報告を進めたい。
    さらに、サルコペニアやサルコペニア症例に対する手術の影響などより詳細な解析を進める。バイオマーカー探索も続ける予定である。

  6. The diagnostic performance and mechanisms of the release into the circulation of novel serum biomarkers for gastric cancer

    Grant number:17K10581  2017.4 - 2020.3

    KANDA Mitsuro

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    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

    Development of high-performance serum biomarkers will likely improve treatment outcomes of patients with gastric cancer (GC). We conducted a prospective multicenter observational study aimed at validating the diagnostic performance of these potential markers. We analyzed serum levels before and after surgery of the three potential biomarkers in patients with GC and healthy volunteers. Quantification of serum and GC tissue levels was performed using an ELISA. Area under the curve values that discriminated patients with GC from healthy controls were-0.7058, 0.6188, and 0.5031 for ANOS1, DPYSL3, and MAGED2, respectively. Serum ANOS1 levels were significantly elevated in patients with stage I GC compared with those of healthy controls and decreased after resection of primary GC lesions. The combination of serum ANOS1 and DPYSL3 levels increased the AUC value that discriminated patients with GC from healthy controls.

  7. Molecule target for treatment and companion diagnostic tool of peritoneal dissemination in gastric cancer

    Grant number:17H04281  2017.4 - 2020.3

    KODERA Yasuhiro

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    Peritoneal metastasis is a frequent cause of death in patients with gastric cancer. The pathophysiology and thus targets for treatment are unknown. Synaptotagmin XIII (SYT13) was expressed in patients with peritoneal recurrence of gastric cancer. Inhibition of SYT13 expression in gastric cancer cell lines was associated with decreased invasion and migration ability of the cells. In vivo experiments using a mouse xenograft model of gastric cancer showed that intraperitoneal administration of SYT13-specific small interfering RNA or antibodies significantly inhibited the growth of peritoneal nodules and prolonged survival. SYT13 expression in primary gastric cancer tissues or ascites fluids had diagnostic potential both in the detection and prediction of peritoneal metastasis of gastric cancer. SYT13 may also be a promising target for the treatment of peritoneal metastasis of gastric cancer.

  8. Identification of molecules driving hepatic metastasis formation of gastric cancer cells

    Grant number:16K19889  2016.4 - 2018.3

    TANAKA Yuri

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    Liver metastasis remains a serious problem in the management of gastric cancer (GC). Transcriptome data identified the overexpression of synaptotagmin VII (SYT7) in GC tissues with hepatic metastasis. SYT7 knockout inhibited the proliferation of GC cells and attenuated cell migration, invasion, and adhesion. The tumorigenicity of SYT7 knockout cells was moderately reduced in a mouse model of subcutaneous metastasis and was more strikingly attenuated in a model of hepatic metastasis. The SYT7 levels in the primary GC tissues were significantly associated with hepatic recurrence, metastasis, and adverse prognosis. SYT7 represents a tool for prediction and monitoring of hepatic metastasis from GC as well as being a promising therapeutic target.

  9. Expression and DNA methylation of SAMSN1 is associated with the malignant phenotype of hepatocellular carcinoma

    Grant number:16K19890  2016.4 - 2018.3

    EZAKA Kazuhiro

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    Identification of sensitive biomarkers for hepatocellular carcinoma (HCC) is required to achieve efficacious personalized therapy. We investigated its expression and methylation status of SAMSN1 in HCC. Analysis of HCC cell lines revealed that hypermethylation of the SAMSN1 promoter correlated with decreased expression of SAMSN1 mRNA and DNA demethylation increased SAMSN1 transcription. SAMSN1 was expressed at significantly lower levels in tumor tissue compared with the corresponding noncancerous tissues. Patients with extrahepatic recurrence exhibited the lowest levels of SAMSN1 expression in resected HCC tissues. The multivariate analysis identified SAMSN1 as an independent prognostic factor of HCC progression. The expression pattern of tissue SAMSN1 protein correlated with that of SAMSN1 mRNA. Circulating DNA methylation of SAMSN1 was difficult to be detected in serum samples. Our findings indicate that tissue SAMSN1 status represent a novel biomarker of the phenotype of HCC.

  10. Elucidation and clinical application of the mechanism of inhibition of liver damage progression by EGFR inhibitor

    Grant number:15K10161  2015.4 - 2018.3

    FUJII TSUTOMU

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    In recent years, researchers reported the effect of inhibiting cirrhosis by epidermal growth factor receptor (EGFR) inhibitors in animal models (Hepatology 2014). In this research, we clarified the mechanism of this phenomenon concretely and aimed at the development of a treatment method from a new viewpoint that suppresses cirrhotic changes of the liver in humans. Examination of protein expression in rat cirrhosis suppression model, examination of marker expression of Hepatic Stellate Cell, and isolation culture and examination of gene / protein expression in human HCC specimens, were performed.

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