Updated on 2021/07/13

写真a

 
TAGAWA Miho
 
Organization
Institute of Materials and Systems for Sustainability Center for Integrated Research of Future Electronics Innovative Devices Section Associate professor
Graduate School
Graduate School of Engineering
Title
Associate professor

Degree 1

  1. Ph.D. ( 2007.12   The University of Tokyo ) 

Research Interests 4

  1. X線小角散乱

  2. nanoparticle

  3. colloidal crystallization

  4. DNA Nanotechnology

Research Areas 5

  1. Nanotechnology/Materials / Nanobioscience

  2. Nanotechnology/Materials / Nanomaterials

  3. Nanotechnology/Materials / Nanometer-scale chemistry

  4. Nanotechnology/Materials / Nanostructural physics

  5. Nanotechnology/Materials / Crystal engineering

Current Research Project and SDGs 1

  1. Creation of Nanosystems by DNA self-assembly

Research History 10

  1. Nagoya University   Institute of Materials and Systems for Sustainability (IMaSS)   Associate professor

    2015.10

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    Country:Japan

  2. Nagoya University   Graduate School of Engineering Department of Materials,Physics and Energy Engineering Advanced Material Process Engineering   associate professor

    2014.4

  3. Nagoya University   Green Mobility Collaborative Research Center   Associate professor

    2014.4 - 2015.9

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    Country:Japan

  4. Nagoya University   Graduate School of Engineering   Associate professor

    2012.5 - 2014.3

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    Country:Japan

  5. brookhaven National Laboratory, Visiting Researcher

    2009.4 - 2012.4

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    Country:United States

  6. JST PRESTO Fellow

    2008.10 - 2013.3

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    Country:Japan

  7. Department of Life Sciences and Institute of Physics, the University of Tokyo, Post-doctoral Fellow

    2008.1 - 2008.9

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    Country:Japan

  8. Department of Life Sciences and Institute of Physics, the University of Tokyo, Research Fellow

    2007.4 - 2007.12

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    Country:Japan

  9. JSPS Research Fellow (DC2)

    2005.4 - 2007.3

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    Country:Japan

  10. Hitachi, Ltd.

    2003.4 - 2004.12

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    Country:Japan

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Education 3

  1. The University of Tokyo   Graduate School, Division of General Culture   Department of Life Sciences and Institute of Physics

    2003.4 - 2007.3

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    Country: Japan

  2. Waseda University   Graduate School, Division of Science and Engineering   Pure and Applied Physics

    1999.4 - 2001.3

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    Country: Japan

  3. Waseda University   Faculty of Science and Engineering   Department of Applied Physics

    1995.4 - 1999.3

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    Country: Japan

Professional Memberships 5

  1. 日本応用物理学会 有機分子・バイオエレクトロニクス分科会   一般幹事

    2014.4 - 2016.3

  2. 日本金属学会   東海支部評議員

    2013.1 - 2016.3

  3. The Japan Society of Applied Physics

  4. 日本放射光学会

  5. The Physical Society of Japan

Committee Memberships 5

  1. ジェンダー・サミット10組織・運営委員会   部会委員  

    2016.9 - 2018.3   

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    Committee type:Government

  2. 日本応用物理学会   男女共同参画委員  

    2016.4 - 2018.3   

  3. 日本応用物理学会 有機分子・バイオエレクトロニクス分科会   一般幹事  

    2014.4 - 2016.3   

  4. 第 51 回日本生物物理学会年会シンポジウム   シンポジウムオーガナイザー  

    2013.2 - 2013.10   

  5. Next30産学フォーラム   コアメンバー  

    2012.7 - 2013.3   

Awards 4

  1. ソロプチミスト日本財団 女性研究者賞

    2019.8   ソロプチミスト日本財団  

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    Award type:Award from publisher, newspaper, foundation, etc.  Country:Japan

  2. 名古屋大学 女性研究者トップリーダー顕彰

    2018.7   名古屋大学  

    田川美穂

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    Country:Japan

  3. Patent Incentive Award

    2016.6   Brookhaven National Laboratory  

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    Country:United States

  4. Patent Incentive Award

    2012.8   ブルックヘブン国立研究所  

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    Country:United States

 

Papers 60

  1. Two-step nanoparticle crystallization via DNA-guided self-assembly and non-equilibrium dehydration process Reviewed

    Hayato Sumi, Noboru Ohta, Hiroshi Sekiguchi, Shunta Harada, Toru Ujihara, Katsuo Tsukamoto, Miho Tagawa

    Crystal Growth & Design     2021.7

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.1c00398

  2. Diamond Family of Nanoparticle Superlattices Reviewed

    Wenyan Liu, Miho Tagawa, Huolin Xin, Tong Wang, Hamed Emamy, Huilin Li, Kevin G. Yager, Francis W. Starr, Alexei V. Tkachenko, Oleg Gang

    Science   Vol. 351 ( 6273 ) page: 582-586   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

  3. Ordered Arrangement of Planar Faults with Picoscale Perfection in Titanium Oxide Natural Superlattices

    Harada Shunta, Kosaka Naoki, Tagawa Miho, Ujihara Toru

    JOURNAL OF PHYSICAL CHEMISTRY C   Vol. 125 ( 20 ) page: 11175 - 11181   2021.5

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    Language:Japanese  

    DOI: 10.1021/acs.jpcc.1c01831

    Web of Science

  4. Synchrotron X-ray topographic image contrast variation of screw-type basal plane dislocations located at different depths below the crystal surface in 4H-SiC

    Fujie Fumihiro, Peng Hongyu, Ailihumaer Tuerxun, Raghothamachar Balaji, Dudley Michael, Harada Shunta, Tagawa Miho, Ujihara Toru

    ACTA MATERIALIA   Vol. 208   2021.4

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  5. Geometrical design of a crystal growth system guided by a machine learning algorithm

    Yu Wancheng, Zhu Can, Tsunooka Yosuke, Huang Wei, Dang Yifan, Kutsukake Kentaro, Harada Shunta, Tagawa Miho, Ujihara Toru

    CRYSTENGCOMM   Vol. 23 ( 14 ) page: 2695 - 2702   2021.4

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    Language:Japanese  

    DOI: 10.1039/d1ce00106j

    Web of Science

  6. Chiral Optical Force Generated by a Superchiral Near-Field of a Plasmonic Triangle Trimer as Origin of Giant Bias in Chiral Nucleation: A Simulation Study

    Niinomi Hiromasa, Sugiyama Teruki, Cheng An-Chieh, Tagawa Miho, Ujihara Toru, Yoshikawa Hiroshi Y., Kawamura Ryuzo, Nozawa Jun, Okada Junpei T., Uda Satoshi

    JOURNAL OF PHYSICAL CHEMISTRY C   Vol. 125 ( 11 ) page: 6209 - 6221   2021.3

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    Language:Japanese  

    DOI: 10.1021/acs.jpcc.0c11109

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  7. Adaptive process control for crystal growth using machine learning for high-speed prediction: application to SiC solution growth

    Dang Yifan, Zhu Can, Ikumi Motoki, Takaishi Masaki, Yu Wancheng, Huang Wei, Liu Xinbo, Kutsukake Kentaro, Harada Shunta, Tagawa Miho, Ujihara Toru

    CRYSTENGCOMM   Vol. 23 ( 9 ) page: 1982 - 1990   2021.3

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    Language:Japanese  

    DOI: 10.1039/d0ce01824d

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  8. 高塩濃度緩衝液中におけるDNA修飾金ナノ粒子のゼータ電位測定 Invited Reviewed

    田川美穂、横森真麻

    光散乱ジャーナルLSアドバンス   Vol. 19   page: 2 - 6   2021.2

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (bulletin of university, research institution)  

  9. Analysis of dislocation line tilt in GaN single crystal by Raman spectroscopy

    Kokubo Nobuhiko, Tsunooka Yosuke, Inotsume Sho, Fujie Fumihiro, Onda Shoichi, Yamada Hisashi, Shimizu Mitsuaki, Harada Shunta, Tagawa Miho, Ujihara Toru

    JAPANESE JOURNAL OF APPLIED PHYSICS   Vol. 60 ( SA )   2021.1

  10. Plasmonic Manipulation of Sodium Chlorate Chiral Crystallization: Directed Chirality Transfer via Contact-Induced Polymorphic Transformation and Formation of Liquid Precursor

    Niinomi Hiromasa, Sugiyama Teruki, Tagawa Miho, Ujihara Toru, Omatsu Takashige, Miyamoto Katsuhiko, Yoshikawa Hiroshi Y., Kawamura Ryuzo, Nozawa Jun, Okada Junpei T., Uda Satoshi

    CRYSTAL GROWTH & DESIGN   Vol. 20 ( 8 ) page: 5493 - 5507   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.0c00693

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  11. Temperature dependence of double Shockley stacking fault behavior in nitrogen-doped 4H-SiC studied by in-situ synchrotron X-ray topography

    Fujie Fumihiro, Harada Shunta, Hanada Kenji, Suo Hiromasa, Koizumi Haruhiko, Kato Tomohisa, Tagawa Miho, Ujihara Toru

    ACTA MATERIALIA   Vol. 194   page: 387 - 393   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.actamat.2020.04.019

    Web of Science

  12. Behavior of Threading Dislocations from GaN Substrate to Epitaxial Layer

    Inotsume Sho, Kokubo Nobuhiko, Yamada Hisashi, Onda Shoichi, Kojima Jun, Ohara Junji, Harada Shunta, Tagawa Miho, Ujihara Toru

    PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS   Vol. 257 ( 4 )   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/pssb.201900527

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  13. Effect of Crystal Orientation of Cu Current Collectors on Cycling Stability of Li Metal Anodes

    Ishikawa Kohei, Harada Shunta, Tagawa Miho, Ujihara Toru

    ACS APPLIED MATERIALS & INTERFACES   Vol. 12 ( 8 ) page: 9341 - 9346   2020.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsami.9b22157

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  14. Protein crystallization in microdroplets with the aid of electrically induced microbubbles Reviewed

    A. Hirao, N. Tottori, M. Yokomori, M.Tagawa, S. S. Sugano, S. Sakuma, Y. Yamanishi

    Proc. of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)     2020

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    Language:English   Publishing type:Research paper (international conference proceedings)  

  15. Application of C-face dislocation conversion to 2 inch SiC crystal growth on an off-axis seed crystal

    Liu Xinbo, Zhu Can, Harada Shunta, Tagawa Miho, Ujihara Toru

    CRYSTENGCOMM   Vol. 21 ( 47 ) page: 7260 - 7265   2019.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c9ce01338e

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  16. Nondestructive visualization of threading dislocations in GaN by micro raman mapping

    Kokubo Nobuhiko, Tsunooka Yosuke, Fujie Fumihiro, Ohara Junji, Onda Shoichi, Yamada Hisashi, Shimizu Mitsuaki, Harada Shunta, Tagawa Miho, Ujihara Toru

    JAPANESE JOURNAL OF APPLIED PHYSICS   Vol. 58   2019.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7567/1347-4065/ab0acf

    Web of Science

  17. Plasmonic Trapping-Induced Crystallization of Acetaminophen

    Niinomi Hiromasa, Sugiyama Teruki, Uda Satoshi, Tagawa Miho, Ujihara Toni, Miyamoto Katsuhiko, Omatsu Takashige

    CRYSTAL GROWTH & DESIGN   Vol. 19 ( 2 ) page: 529-537   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.8b01361

    Web of Science

  18. High-speed prediction of computational fluid dynamics simulation in crystal growth

    Tsunooka Yosuke, Kokubo Nobuhiko, Hatasa Goki, Harada Shunta, Tagawa Miho, Ujihara Toru

    CRYSTENGCOMM   Vol. 20 ( 41 ) page: 6546-6550   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c8ce00977e

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  19. Determination of edge-component Burgers vector of threading dislocations in GaN crystal by using Raman mapping

    Kokubo Nobuhiko, Tsunooka Yosuke, Fujie Fumihiro, Ohara Junji, Onda Shoichi, Yamada Hisashi, Shimizu Mitsuaki, Harada Shunta, Tagawa Miho, Ujihara Toru

    APPLIED PHYSICS EXPRESS   Vol. 11 ( 11 )   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7567/APEX.11.111001

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  20. In Situ Observation of Chiral Symmetry Breaking in NaClO3 Chiral Crystallization Realized by Thermoplasmonic Micro-Stirring

    Niinomi Hiromasa, Sugiyama Teruki, Tagawa Miho, Harada Shunta, Ujihara Tom, Uda Satoshi, Miyamoto Katsuhiko, Omatsu Takashige

    CRYSTAL GROWTH & DESIGN   Vol. 18 ( 8 ) page: 4230-4239   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.8b00420

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  21. Direct observation of stacking fault shrinkage in 4H-SiC at high temperatures by in-situ X-ray topography using monochromatic synchrotron radiation

    Fujie Fumihiro, Harada Shunta, Koizumi Haruhiko, Murayama Kenta, Hanada Kenji, Tagawa Miho, Ujihara Toru

    APPLIED PHYSICS LETTERS   Vol. 113 ( 1 )   2018.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1063/1.5038189

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  22. Development of angle-resolved spectroscopy system of electrons emitted from a surface with negative electron affinity state

    Ichihashi Fumiaki, Dong Xinyu, Inoue Akito, Kawaguchi Takahiko, Kuwahara Makoto, Ito Takahiro, Harada Shunta, Tagawa Miho, Ujihara Toru

    REVIEW OF SCIENTIFIC INSTRUMENTS   Vol. 89 ( 7 )   2018.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1063/1.5021116

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  23. Detection of edge component of threading dislocations in GaN by Raman spectroscopy

    Kokubo Nobuhiko, Tsunooka Yosuke, Fujie Fumihiro, Ohara Junji, Hara Kazukuni, Onda Shoichi, Yamada Hisashi, Shimizu Mitsuaki, Harada Shunta, Tagawa Miho, Ujihara Toru

    APPLIED PHYSICS EXPRESS   Vol. 11 ( 6 )   2018.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7567/APEX.11.061002

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  24. Structure control of nanoparticle superstructures with DNA nanostructure Invited

    Tagawa Miho, Sogai Takumi, Sumi Hayato, Kojima Shoko

    Impact   Vol. 2018 ( 3 ) page: 72-73   2018.6

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    Authorship:Lead author   Language:English  

    DOI: 10.21820/23987073.2018.3.72

  25. Temperature dependence of carrier relaxation time in gallium phosphide evaluated by photoemission measurements

    Ichihashi Fumiaki, Kawaguchi Takahiko, Dong Xinyu, Kuwahara Makoto, Ito Takahiro, Harada Shunta, Tagawa Miho, Ujihara Toru

    AIP ADVANCES   Vol. 7 ( 11 )   2017.11

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    DOI: 10.1063/1.4997800

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  26. Phase transition process in DDAB supported lipid bilayer Reviewed

    Takumi Isogai, Sakiko Nakada, Naoya Yoshida, Hayato Sumi, Ryugo Tero, Shunta Harada, Toru Ujihara, Miho Tagawa

    Journal of Crystal Growth   Vol. 468   page: 88 - 92   2017.6

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    DOI: 10.1016/j.jcrysgro.2016.09.063

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  27. Two-step SiC solution growth for dislocation reduction Reviewed

    K. Murayama, T. Hori, S. Harada, S. Xiao, M. Tagawa, T. Ujihara

    J. Cryst. Growth   Vol. 468   page: 874 - 878   2017.6

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    DOI: 10.1016/j.jcrysgro.2016.11.100

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  28. Morphology of AlN whiskers grown by reacting N 2 gas and Al vapor Reviewed

    M. Matsumoto, H. Saitou, Y. Takeuchi, S. Harada, M. Tagawa, T. Ujihara

    J. Cryst. Growth   Vol. 468   page: 576 - 580   2017.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jcrysgro.2016.11.127

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  29. Crystal Orientation Dependence of Precipitate Structure of Electrodeposited Li Metal on Cu Current Collectors Reviewed

    K. Ishikawa, Y. Ito, S. Harada, M. Tagawa, T. Ujihara

    Cryst. Growth Des.   Vol. 17 ( 5 ) page: 2379 - 2385   2017.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.6b01710

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  30. ナノ粒子超格子のダイアモンド系列 Invited

    田川美穂

    サイエンス誌に載った日本人研究者     page: 21   2017.3

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    Authorship:Lead author   Language:Japanese  

  31. Plasmonic Heating-Assisted Laser-Induced Crystallization from a NaClO3 Unsaturated Mother Solution Reviewed

    H. Niinomi, T. Sugiyama, M. Tagawa, M. Maruyama, T. Ujihara, T. Omatsu, Y. Mori

    Cryst. Growth Des.   Vol. 17 ( 2 ) page: 809 - 818   2017.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.6b01657

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  32. SiC solution growth on Si face with extremely low density of threading screw dislocations for suppression of polytype transformation Reviewed

    K. Murayama, T. Hori, S. Harada, S. Xiao, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 897   page: 24-27   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4028/www.scientific.net/MSF.897.24

  33. Formation of basal plane dislocations introduced by collision of macrosteps on growth surface during SiC solution growth Reviewed

    T. Hori, K. Murayama, S. Harada, S. Xiao, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 897   page: 28-31   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4028/www.scientific.net/MSF.897.28

  34. Solvent design for high-purity SiC solution growth Reviewed

    S. Harada, G. Hatasa, K. Murayama, T. Kato, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 897   page: 32-35   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4028/www.scientific.net/MSF.897.32

  35. Effect of magnesium ion concentration on two-dimensional structure of DNA-functionalized nanoparticles on supported lipid bilayer Reviewed

    Takumi Isogai, Eri Akada, Sakiko Nakada, Naoya Yoshida, Ryugo Tero, Shunta Harada, Toru Ujihara, Miho Tagawa

    Japanese Journal of Applied Physics   Vol. 55   page: 03DF11   2016

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: in press

  36. Conversion behavior of threading screw dislocations on C face with different surface morphology during 4H-SiC solution growth

    S. Xiao, S. Harada, K. Murayama, M. Tagawa, T. Ujihara

    Cryst. Growth Des.   Vol. 16   page: 6436-6439   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.cgd.6b01107

  37. Polytype control by activity ratio of silicon to carbon during SiC solution growth using multicomponent solvents Reviewed

    A. Horio, S. Harada, D. Koike, K. Murayama, K. Aoyagi, T. Sakai, M. Tagawa, T. Ujihara

    Jpn. J. Appl. Phys.   Vol. 55   page: 01AC01   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7567/JJAP.55.01AC01

  38. Spatial Distribution of Carrier Concentration in 4H-SiC Crystal Grown by Solution Method Reviewed

    Z. Wang, T. Kawaguchi, K. Murayama, K. Aoyagi, S. Harada, M. Tagawa, T. Sakai, T. Kato, T. Ujihara

    Mater. Sci. Forum   Vol. 858   page: 57-60   2016

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    DOI: MSF.858.57

  39. High-Speed Solution Growth of Single Crystal AlN from Cr-Co-Al Solvent Reviewed

    S. Watanabe, M. Nagaya, Y. Takeuchi, K. Aoyagi, K. Aoyagi, S. Harada, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 858   page: 1210-1213   2016

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    DOI: MSF.858.1210

  40. Enantioselective amplification on circularly polarized laser-induced chiral nucleation from a NaClO 3 solution containing Ag nanoparticles Reviewed

    H. Niinomi, T. Sugiyama, M. Tagawa, K. Murayama, S. Harada, T. Ujihara

    CrystEngComm   Vol. 18   page: 7441-7448   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/C6CE01464J

  41. Control of interface Shape by Non-Axisymmetric Solution Convection in Top-Seeded Solution Growth of SiC Crystal Reviewed

    D. Koike, T. Umezaki, K. Murayama, K. Aoyagi, S. Harada, M. Tagawa, T. Sakai, T. Ujihara

    Mater. Sci. Forum   Vol. 821-823   page: 18-21   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4028/www.scientific.net/MSF.821-823.18

  42. Dislocation Conversion during SiC Solution Growth for High-quality Crystals Reviewed

    S. Harada, Y. Yamamoto, S. Xiao, D. Koike, T. Mutoh, K. Murayama, K. Aoyagi, T. Sakai, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 821-823   page: 3-8   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.4028/www.scientific.net/MSF.821-823.3

  43. Forming two-dimensional structure of DNA-functionalized Au nanoparticles via lipid diffusion in supported lipid bilayers Reviewed

    T. Isogai, A. Piednoir, E. Akada, Y. Akahoshi, R. Tero, S. Harada, T. Ujihara, M. Tagawa

    J. Cryst. Growth   Vol. 401   page: 494-498   2014.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jcrysgro.2014.01.032

  44. Direct measurement of conduction miniband structure in superlattice by visible-light photoemission spectroscopy Reviewed

    F. Ichihashi, D. Shimura, K. Nishitani, T. Kawaguchi, M. Kuwahara, T. Ito, S. Harada, H. Katsuno, M. Tagawa, T.Ujihara

    Proceedings of Photovoltaic Specialist Conference (PVSC)     page: 2882-2885   2014.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1109/PVSC.2014.6925534

  45. DNAと基板担持脂質二重膜とを用いたナノ粒子の結晶化 Invited

    田川美穂

    応用物理学会有機分子・バイオエレクトロニクス分科会会誌   Vol. 25 ( 2 ) page: 145-148   2014.5

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  46. Surface Morphology and Threading Dislocation Conversion Behavior during Solution Growth of 4H-SiC Using Al-Si Solvent Reviewed

    S. Harada, Y. Yamamoto, S. Y. Xiao, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 778 ( 780 ) page: 67-70   2014.2

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  47. Low-dislocation-density 4H-SiC crystal growth utilizing dislocation conversion during solution method Reviewed

    Y. Yamamoto, S. Harada, K. Seki, A. Horio, T. Mitsuhashi, D. Koike, M. Tagawa, and T. Ujihara

    Applied Physics Express   Vol. 7   page: 065501   2014

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  48. Different behavior of threading edge dislocation conversion during the solution growth of 4H-SiC depending on the Burgers vector Reviewed

    S. Harada, Y. Yamamoto, K. Seki, A. Horio, M. Tagawa, T. Ujihara

    Acta Materialia   Vol. 81   page: 284-290   2014

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.actamat.2014.08.027

  49. Surface Morphology and Threading Dislocation Conversion Behavior during Solution Growth of 4H-SiC Using Al-Si Solvent

    S. Harada, Y. Yamamoto, S. Y. Xiao, M. Tagawa, T. Ujihara

    Mater. Sci. Forum   Vol. 778-780   page: 67-70   2014

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  50. Low-dislocation-density 4H-SiC crystal growth utilizing dislocation conversion during solution method Reviewed

    Y. Yamamoto, S. Harada, K. Seki, A. Horio, T. Mitsuhashi, D. Koike, M. Tagawa, and T. Ujihara

    Applied Physics Express   Vol. 7   page: 065501   2014

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7567/APEX.7.065501

  51. Evolution of threading screw dislocation conversion during solution growth of 4H-SiC Reviewed

    S. Harada, Y. Yamamoto, K. Seki, A. Horio, T. Mitsuhashi, M. Tagawa, and T. Ujihara

    APL Mater.   Vol. 1   page: 022109   2013.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  52. Influence of Solution Flow on Step Bunching in Solution Growth of SiC Crystals Reviewed

    Can Zhu, Shunta Harada, Kazuaki Seki, Huayu Zhang, Hiromasa Niinomi, Miho Tagawa, and Toru Ujihara

    Cryst. Growth Des.   Vol. 13 ( 8 ) page: 3691-3696   2013.7

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    Language:English   Publishing type:Research paper (scientific journal)  

  53. Evolution of threading screw dislocation conversion during solution growth of 4H-SiC Reviewed

    S. Harada, Y. Yamamoto, K. Seki, A. Horio, T. Mitsuhashi, M. Tagawa, and T. Ujihara

    APL Mater.   Vol. 1 ( 2 ) page: 022109   2013

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    Language:English   Publishing type:Research paper (scientific journal)  

  54. 3PT110 A Growth mechanism of DNA tile array Reviewed

    Yuki Matsubara, Nao Otani, Miho Tagawa, Akira Suyama

      Vol. 52 ( supplement ) page: S156   2012

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    Language:English  

    DOI: 10.2142/biophys.52.S156_4

  55. Stabilization of DNA nanostructures by photo-cross-linking Reviewed

    Miho Tagawa, Koh-ichiroh Shohda, Kenzo Fujimoto, Akira Suyama

    Soft Matter   Vol. 7   page: 10931-10934   2011

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  56. Heat-resistant DNA tile arrays constructed by template-directed photoligation through 5-carboxyvinyl-2'-deoxyuridine Reviewed

    Miho Tagawa, Koh-ichiroh Shohda, Kenzo Fujimoto, Tadashi Sugawara, Akira Suyama

    Nucleic Acids Research   Vol. 35 ( 21 ) page: e140   2007

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  57. Heat-resistant DNA arrays constructed by self-assembly Reviewed

    Miho Tagawa, Koh-ichiroh Shohda, Kenzo Fujimoto, Akira Suyama

    Proceedings of NanoBio-Tokyo 2006     page: 383-384   2006

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    Authorship:Lead author   Language:English  

  58. TMC (100) surface relaxation studied with low-energy-electron-diffraction intensity analysis Reviewed

    Miho Tagawa, Toyosei Kawasaki, Chuhei Oshima, Shigeki Otani, Ayato Nagashima

    Surface Science   Vol. 517   page: 59-64   2002

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  59. TiC (100) surface relaxation studied with low-energy-electron-diffraction intensity analysis Reviewed

    Miho Tagawa, Masahiko Okuzawa, Toyosei Kawasaki, Chuhei Oshima, Shigeki Otani, Ayato Nagashima

    Physical Review B   Vol. 63   page: 73407   2001

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  60. Pt(755)とTiC(755)上に成長させた単原子層グラファイトの電子状態 Reviewed

    大野僚子, 細田真希, 奥沢昌彦, 田川美穂, 大島忠平, 大谷茂樹

    炭素   Vol. 195   page: 400-404   2000

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

▼display all

Presentations 42

  1. DNAガイドのナノ粒子結晶化:構造制御と結晶対称性を維持した収縮制御 Invited

    田川美穂, 鷲見隼人, 横森真麻,  前田勇士, 太田昇, 関口博史,  原田俊太, 宇治原徹

    日本物理学会第76回年次大会  2021.3.13  日本物理学会

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン   Country:Japan  

  2. 放射光トポグラフィーによるSiC中の基底面転位の深さ評価 International coauthorship

    藤榮 文博, Hongyu Peng, Tuerxun Ailihumaer, Balaji Raghothamachar, Michael Dudley, 原田 俊太, 田川 美穂, 宇治原 徹

    第68回応用物理学会学術講演会  2021.3.18  日本応用物理学会

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  3. 面欠陥周期配列を含むCr添加酸化チタン多結晶の熱伝導率の温度依存性

    杉本 峻也, 金 柯怜, 竹内 恒博, 田川 美穂, 宇治原 徹, 原田 俊太

    第68回応用物理学会学術講演会  2021.3.16  日本応用物理学会

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  4. 面欠陥周期配列を含む自然超格子酸化チタンの構造制御と熱輸送特性

    原田 俊太, 小坂 直輝, 杉本 峻也, 八木 貴志, 田川 美穂, 宇治原 徹

    第68回応用物理学会学術講演会  2021.3.16  日本応用物理学会

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  5. Protein crystallization in microdroplets with the aid of electrically induced microbubbles Invited International conference

    A. Hirao, N. Tottori, M. Yokomori, M. Tagawa, S. S. Sugano, S. Sakuma, Y. Yamanishi

    The 34th IEEE Int. Conf. on Micro Electro Mechanical Systems (IEEE MEMS 2021)  2021.1.26  IEEE

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    Event date: 2021.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Gainesville, FL, USA   Country:United States  

  6. Strain imaging of threading dislocations in GaN crystal by micro-Raman spectroscopy Invited

    2020.12.10 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  7. Prediction system of CFD simulation in solution growth constructed by machine learning - Application for SiC top-seeded solution growth – International conference

    Toru Ujihara, Yosuke Tsunooka, Tomoki Endo, Can Zhu, Shunta Harada, Miho Tagawa

    17th China International Forum on Solid State Lighting & 2020 International Forum on Wide Bandgap Semiconductors (SSLCHINA&IFWS 2020)  2020.11.24  China Solid State Lighting Alliance (CSA) , China Advanced Semiconductor Industry Innovation Alliance (CASA)

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    Event date: 2020.11

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Guangdong, China   Country:China  

  8. DNA修飾ナノ粒子コロイド結晶化における結晶性に及ぼす塩濃度の影響

    鷲見隼人, 太田昇, 関口博史, 原田俊太, 宇治原徹, 田川美穂

    第49回結晶成長国内会議(JCCG-49)  2020.11.11  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  9. DNA修飾ナノ粒子超格子のサイズ・結晶性に及ぼす修飾DNA鎖長の影響

    鈴木康平, 太田昂, 関口博史, 鷲見隼人, 横森真麻, 原田俊太, 宇治原徹, 田川美穂

    第49回結晶成長国内会議(JCCG-49)  2020.11.11  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  10. DNA修飾ナノ粒子超格子結晶化における塩濃度が粒子間相互作用に与える影響

    楊冰琦, 鷲見隼人, 太田昇, 関口博史, 原田俊太, 宇治原徹, 田川美穂

    第49回結晶成長国内会議(JCCG-49)  2020.11.11  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  11. CFDによるステップバンチング挙動シミュレーション

    劉欣博, 党一帆, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.11  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  12. 長時間安定SiC溶液成長における経時変化のシミュレーションと最適化

    党一帆, 朱燦, 幾見基希, 郁万成,黄威, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.10  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  13. 時間的な温度差により熱エネルギーを電気に変換する熱電池の構築

    陳曄, 石川晃平, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  14. 機械学習支援による溶液成長法を用いた6インチSiC作製手法の確立

    郁万成, 朱燦, 角岡洋介, 黄威, 党一帆, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  15. 機械学習を用いたSiC溶液法の温度・流速分布の次元削減とロバスト性評価

    磯野優, 小山幸典, 沓掛健太郎, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  16. SiC昇華法におけるベイズ最適化を用いた高品質・高速成長条件の探索

    井上凱喜, 沓掛健太郎, 原田俊太,田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  17. 溶液法によるBPDフリー3インチSiC結晶の成長

    朱燦, 郁万成, 黄威, 幾見基希, 党一帆, 海野高天, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  18. SiC溶液成長における境界層とステップバンチングの関係

    海野高天, 朱燦, 原田俊太, 劉欣博, 幾見基希, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  19. Si-Y溶媒を用いたSiC溶液成長中の自然核生成による多結晶析出の抑制

    幾見基希, 朱燦, 原田俊太, 党一帆, 海野高天, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  20. SiC溶液成長における機械学習を用いた固-液界面形状の時間変化の推定

    高石将輝, 党一帆, 沓掛健太朗, 原田俊太, 田川美穂, 宇治原徹

    第49回結晶成長国内会議(JCCG-49)  2020.11.9  日本結晶成長学会

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  21. イオン注入シミュレーションに対する機械学習の適用

    蜂谷涼太, 沓掛健太朗, 原田俊太, 田川美穂, 宇治原徹

    第81回応用物理学会秋季学術講演会  2020.9.9  応用物理学会

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン   Country:Japan  

  22. Effect of magnesium ion concentration on the two-dimensional structure of DNA-functionalized nanoparticles on supported lipid bilayer International conference

    Takumi Isogai , Eri Akada, Sakiko Nakada, Naoya Yoshida, Ryugo Tero, Shunta Harada, Toru Ujihara, Miho Tagawa

    Eighth International Conference on Molecular Electronics and Bioelectronics (M&BE) 

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    Event date: 2015.6

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  23. Lipid diffusion and phase transition: Influence on DNA-functionalised nanoparticle adsorbates International conference

    S. Nakada, E. Akada, T. Isogai, N. Yoshida, R. Tero, S. Harada, T. Ujihara, M. Tagawa

    5th International Colloids Conference 

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    Event date: 2015.6

    Language:English   Presentation type:Poster presentation  

    Country:Netherlands  

  24. Two-dimensional assembly of Au nanoparticles through DNA hybridization on supported lipid bilayer International conference

    T. Isogai, E. Akada, S. Nakada, R. Tero, S. Harada, T. Ujihara and M. Tagawa

    20th International Conference on DNA Computing and Molecular Programming (DNA20) 

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    Event date: 2014.9

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  25. 脂質二重膜上におけるDNA被覆金ナノ粒子の拡散現象

    中田咲子,赤田英里, 磯貝卓巳,手老龍吾,原田俊太,宇治原徹,田川美穂

    第75回応用物理学会秋季学術講演会 

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    Event date: 2014.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:北海道大学、札幌   Country:Japan  

  26. DNA-mediated Nanoparticle Crystallization International conference

    Miho Tagawa, Oleg Gang, Takumi Isogai, Sakiko Nakada, Eri Akada, Shunta Harada, Toru Ujihara

    Material Architectonics on Sustainable Action MASA 2014 

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    Event date: 2014.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  27. DNAと基板担持脂質二重膜とを用いたナノ粒子の結晶化

    田川美穂

    応用物理学会 有機分子・バイオエレクトロニクス分科会 研究会 

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    Event date: 2014.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:キャンパスプラザ京都   Country:Japan  

  28. 基板担持脂質二重膜を用いたDNA被覆金ナノ粒子の2次元結晶化

    磯貝卓巳, 赤田英里, 勝野弘康, Piednoir Agnes, 赤星祐樹, 手老龍吾, 原田俊太, 宇治原 徹, 田川美穂

    日本化学会第94春季年会 

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    Event date: 2014.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学   Country:Japan  

  29. Two-dimensional crystallization of DNA-functionalized Au nanoparticles using lipid diffusion International conference

    T.Isogai, E.Akada, A.Piednoir, Y.Akahoshi, R.Tero, S.Harada, T.Ujihara, M.Tagawa

    ISETS '13 

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    Event date: 2013.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  30. 脂質二重膜を利用したDNA被覆金ナノ粒子の2次元結晶化

    磯貝卓巳,赤田英里,Agnes Piednoir,赤星祐樹,手老龍吾,原田俊太,宇治原徹,田川美穂

    公益社団法人 応用物理学会 SC東海地区学術講演会2013(JSAP SCTS 2013) 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋大学   Country:Japan  

  31. DNAと脂質二重膜を用いたナノ粒子の2次元結晶化

    磯貝卓巳,赤田英里,Agnes Piednoir,赤星祐樹,手老龍吾,原田俊太,宇治原徹,田川美穂

    日本結晶成長学会 第43回結晶成長国内会議(NCCG-43) 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長野市生涯学習センター   Country:Japan  

  32. ブラウニアン動力学法を用いた2次元2成分結晶の構造形成シミュレーション

    勝野弘康,田川美穂,宇治原徹

    日本結晶成長学会 第43回結晶成長国内会議(NCCG-43) 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:長野市生涯学習センター   Country:Japan  

  33. DNAセルフアセンブリによるナノ粒子超構造制御

    田川 美穂, ガング オレグ, 磯貝 卓巳, 赤田 英里, 宇治原 徹

    第 51 回日本生物物理学会年会 シンポジウム 反応場デザインによる生命現象の再構成 -創って知る生物物理- 

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    Event date: 2013.10

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

    Venue:国立京都国際会館   Country:Japan  

  34. DNA-mediated Nanoparticle Assembly International conference

    Miho Tagawa

    The 2nd International Workshop on Convergence in Condensed Matter and Nano Physics 

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    Event date: 2013.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Korea, Republic of  

  35. 脂質分子をキャリアとしたDNA被覆金ナノ粒子の2次元結晶化

    磯貝卓巳,Agnes Piednoir,赤田英里,赤星祐樹,手老龍吾,原田俊太,宇治原徹,田川美穂

    公益社団法人応用物理学会 2013年 第74回応用物理学会秋季学術講演会 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:同志社大学京田辺キャンパス   Country:Japan  

  36. Forming two-dimensional structure of DNA-functionalized Au nanoparticles via lipid diffusion in supported lipid bilayers International conference

    T. Isogai, A. Piednoir, E. Akada, Y. Akahoshi, R. Tero, S. Harada, T. Ujihara, M. Tagawa

    17th International Conference on Crystal Growth and Epitaxy (ICCGE-17) 

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Poland  

  37. Two-dimensional crystallization of DNA-functionalized nanoparticles via lipid diffusion in supported lipid bilayers International conference

    T. Isogai, A. Piednoir, E. Akada, Y. Akahoshi, R. Tero, S. Harada, T. Ujihara, M. Tagawa

    15th International Summer School on Crystal Growth(ISSCG-15) 

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    Event date: 2013.8

    Language:English   Presentation type:Poster presentation  

    Country:Poland  

  38. Nanoparticle Assembly mediated by Designed DNA Nanostructures International conference

    Miho Tagawa

    Programmable Self-Assembly of Matter 

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    Event date: 2013.6 - 2013.7

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  39. 脂質分子の拡散によるDNA被覆金ナノ粒子の2次元構造体形成

    磯貝卓巳,Agnes Piednoir,赤田英里,祐樹赤星,手老龍吾,原田俊太,宇治原徹,田川美穂

    2012年春季 第60回 応用物理学関係連合講演会 

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    Event date: 2013.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神奈川工科大学   Country:Japan  

  40. DNAナノテクノロジー:DNAガイドのナノ粒子結晶化

    田川美穂、Oleg Gang、磯貝卓巳、赤星祐樹、赤田英里、Piednoir Agnes、原田俊太、宇治原徹

    2012年度中部支部講演会 

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    Event date: 2013.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋大学   Country:Japan  

  41. Gold Nanoparticle Assembly mediated by DNA Nanostructures International conference

    Miho Tagawa, Kevin Yanger, Oleg Gang

    The 39th International Symposium on Nucleic Acids Chemistry (ISNAC2012) 

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    Event date: 2012.11

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  42. DNA- covered nanoparticle assembly mediated by DNA nanostructures International conference

    Miho Tagawa, Oleg Gang

    Japan-Netherlands Symposium on Crystal Growth -Theory and in situ Measurements- 

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    Event date: 2012.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 7

  1. Delivery of long-chain DNA by the novel bubble injector and microstructures

    2019.10 - 2024.3

    CREST "Large-scale genome synthesis and cell programming" 

    Yoko Yamanishi

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    Grant type:Competitive

  2. 生体の巧妙なものづくりの仕組みを利用した新奇材料創製:DNAプログラマブル自己集合によるナノ粒子超格子構造の高品質コロイド結晶作製と構造制御

    2017.10 - 2018.9

  3. DNAをリガンドとしたナノ粒子のプログラマブル結晶化によるウルフ多面体型コロイド単結晶の作製と構造制御

    2017.9 - 2019.9

  4. タンパク質結晶化のFeasibility Study

    2017.4 - 2019.3

    企業からの受託研究 

    磯貝卓巳

  5. 平成27年度共同研究助成制度(女性研究者研究活動支援事業(連係型))

    2015.10 - 2016.3

    国内共同研究 

  6. 二次元フォトニック結晶実現のためのDNAを用いたナノ粒子のプログラマブル結晶化

    2015.4 - 2016.3

    学内共同研究 

  7. DNAセルフアセンブリによるナノシステムの創製

    2008.10 - 2013.3

    JSTさきがけ「ナノシステムと機能創発」 

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    Grant type:Competitive

    ナノテクノロジーにおける重要課題の一つとして、分子や微粒子などのナノ部品をボトムアップ的にアセンブリするためのプログラマブルな技術の開発があります。本研究では、DNAタイル(数本のDNA分子で作られた方形状のナノ構造体)をセルフアセンブリして構築したDNAタイルアレイを足場として、ナノ部品をプログラマブルにアセンブリし、トップダウン的な微細化技術の限界を超える技術の開発を目指します。

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KAKENHI (Grants-in-Aid for Scientific Research) 9

  1. 簡便なタンパク質構造解析に向けた規則配列化のためのDNA規則的多孔構造創製

    2019.7 - 2022.3

    科学研究費補助金  研究成果公開促進費 (研究成果公開発表)

    田川美穂

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    Authorship:Principal investigator 

  2. 簡便なタンパク質構造解析に向けた規則配列化のためのDNA規則的多孔構造創製

    Grant number:19K22103  2019.6 - 2022.3

    挑戦的研究(萌芽)

    田川 美穂

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    Authorship:Principal investigator 

    Grant amount:\6240000 ( Direct Cost: \4800000 、 Indirect Cost:\1440000 )

    本研究は、タンパク質立体構造解析の簡便化に向けたタンパク分子規則配列化のためのDNA規則的多孔構造(DNA結晶スポンジ)の創製を目的とする。これにより、従来のタンパク質立体構造解析においてボトルネックとなっている網羅的実験が必要な「タンパク結晶化」を介することなく立体構造解析を可能にするための新手法の開発を目指す。従来のDNAナノ構造体設計法(DNAタイル、DNAオリガミ)とは異なる「DNA修飾ナノ粒子超格子(DNA-NP)の結晶化機構を模した設計法」でDNA結晶スポンジを実現する狙いである。
    研究の進め方としては、申請時の予定通り進めた課題と変更が生じた課題があるが、着実に研究を進展させることができた。
    DNA修飾ナノ粒子結晶のデザインに関しては、空孔サイズの大きい所謂スカスカなDNA修飾ナノ粒子結晶の高品質成長に取り組んだ。効率よくゲスト分子の取り込みを行うためには、粒径の揃った単結晶に成長させることが理想的であるが、スカスカな結晶になる程結晶性の良い単結晶を作製することが難しい。結晶化条件を最適化することで、スカスカなDNA修飾ナノ粒子結晶の高品質化に取り組んだ。
    DNA修飾ナノ粒子結晶にゲスト分子を取り込む課題は、透過型電子顕微鏡(TEM)、及び超解像顕微鏡により、DNA修飾ナノ粒子結晶の像と同領域にゲスト分子が確認された。DNA修飾ナノ粒子結晶が水溶性の結晶スポンジとして機能することを示唆しているといえる。
    ゲスト分子の取り込み過程には、当初予想していた以上に様々な物理があり、学術的に深く考察する必要があることがわかってきた。今年度は、ゲスト分子取り込み前に行うDNA修飾ナノ粒子結晶の乾燥・収縮過程に関する研究を深めた。乾燥(脱水)してもDNA修飾ナノ粒子結晶の対称性を維持できる条件に関しては、空孔の小さな結晶においては解明されつつあるが、空孔の大きいスカスカな結晶に関しては、今後も引き続き取り組む予定である。
    本研究は、申請書記載の実験計画通りに進展した部分と、進め方に変更が生じながらも予期せぬ成果が得られた部分がある。DNA修飾ナノ粒子結晶にゲスト分子を取り込む課題は、予定通り進んでいる。同時に、ゲスト分子の取り込み過程には、当初予想していた以上に様々な課題があり、学術的に深く考察する必要性があることがわかってきた。今年度は、ゲスト分子取り込み前に行うDNA修飾ナノ粒子結晶の乾燥過程に関する研究を深め、良い成果が得られた。よって、おおむね順調に進展している、と言える。
    DNA修飾ナノ粒子結晶へのゲスト分子取り込み及び空孔への配置に関しては、研究が進展するにつれ、追及すべき課題が多くあることがわかってきた。DNA修飾ナノ粒子結晶デザインと空孔の大きさ、結晶対称性とゲスト分子取り込み効率、DNA修飾ナノ粒子結晶及びゲスト分子のチャージと取り込み効率との関係、静電相互作用によりゲスト分子を取り込むためのDNA修飾ナノ粒子結晶内部のチャージコントロール等が重要項目である。
    2020年度は、①DNA修飾ナノ粒子結晶デザインの改良とゲスト分子取り込み効率の向上、②乾燥を伴わないゲスト分子の取り込み方法の模索(塩濃度変化による結晶収縮・膨張、及び結晶内部のチャージコントロール)、を優先的に進める。

  3. DNA修飾ナノ粒子の高品質単結晶成長法の開発

    2019.4 - 2024.3

    科学研究費補助金  基盤研究(B)

    田川美穂

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    Authorship:Principal investigator 

  4. High-quality single crystal growth of DNA-functionalized nanoparticles

    Grant number:19H02555  2019.4 - 2024.3

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    Authorship:Principal investigator 

    Grant amount:\16900000 ( Direct Cost: \13000000 、 Indirect Cost:\3900000 )

  5. ナノスケール熱制御に向けたナノ粒子超格子構造のプログラマブル融合化 研究課題

    2016.4 - 2019.3

    科学研究費補助金  挑戦的萌芽研究

    田川美穂

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    Authorship:Principal investigator 

  6. Programmable surface fusion of the nanoparticle superlattice for nanoscale thermal management

    Grant number:16K13614  2016.4 - 2019.3

    Tagawa Miho

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    Authorship:Principal investigator 

    Grant amount:\3770000 ( Direct Cost: \2900000 、 Indirect Cost:\870000 )

    We demonstrated the successful wulff polyhedral formation of direct dehydrated DNA-guided nanoparticle single crystals.
    DNA-functionalized nanoparticlew were crystallized through slowly cooling from 65 C to 25 C. The crystal structure of assembled DNA-NP superlattices were analyzed by SAXS before and after dehydrations. Dried samples were also imaged by SEM and TEM. The perfect forming conditions after dehydration were adjusted by changing volume fraction of nanoparticles per unit in solution. We finally confirmed wulff polyhedral formation of DNA-NP superlattices at higher volume fractions. We have succeeded, for the first time, in the structure analysis of direct dehydrated DNA-NP superlattices. We also confirmed the surface fusion of nearest-neighboring nanoparticles in a DNA-NP superlattice by electron beam irradiation. The technique has great potential as assembling method of precursor of phononic crystals.

  7. DNAナノ構造体によるナノ粒子超構造の構造制御

    2013.4 - 2017.3

    科学研究費補助金  若手研究(A)

    田川美穂

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    Authorship:Principal investigator 

  8. DNAセルフアセンブリによる分子準結晶の実現

    2013.4 - 2016.3

    科学研究費補助金  挑戦的萌芽研究

    田川美穂

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    Authorship:Principal investigator 

  9. プログラム可能なDNAナノデバイスの構築

    2005.4 - 2007.3

    科学研究費補助金 

    田川美穂

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    Authorship:Principal investigator 

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Industrial property rights 4

  1. ナノ粒子結晶およびその製造方法

    田川美穂、横森真麻

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    Applicant:国立大学法人名古屋大学

    Application no:特願 2019-169737  Date applied:2019.9

  2. 超格子構造体、およびその製造方法

    鷲見隼人、田川美穂、宇治原徹

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    Applicant:国立大学法人名古屋大学

    Application no:2017-046570  Date applied:2017.3

    Country of applicant:Domestic  

  3. 2次元ナノ粒子構造体及びその製造方法

    田川美穂、宇治原徹、磯貝卓巳、赤田英理

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    Applicant:国立大学法人名古屋大学

    Application no:2013-126144  Date applied:2013.6

    Announcement no:2015-000450 

    Patent/Registration no:6086595  Date registered:2017.2 

    Country of applicant:Domestic  

  4. Rational Assembly of Nanoparticle Superlattices with Designed Lattice Symmetries

    Oleg Gang, Fang Lu, Miho Tagawa

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    Application no:61/587,786  Date applied:2012.1

    Country of applicant:Foreign country  

 

Teaching Experience (On-campus) 32

  1. 学生実験1

    2021

  2. マテリアル工学演習

    2021

  3. 固体物理演習

    2021

  4. Analytical Chemistry

    2020

  5. 固体物理演習

    2020

  6. 学生実験1

    2020

  7. マテリアル工学演習

    2020

  8. 機器分析概論

    2020

  9. マテリアル量子工学(量子力学)

    2020

  10. 学生実験1

    2019

  11. マテリアル量子工学(量子力学)

    2019

  12. 固体物理演習

    2019

  13. マテリアル量子工学(量子力学)

    2018

  14. 材料工学実験第2

    2018

  15. 基礎セミナーA

    2017

  16. 材料工学実験第2

    2017

  17. 工場見学

    2016

  18. 材料工学序論

    2016

  19. 材料工学実験第2

    2016

  20. 材料工学実験基礎

    2016

  21. マテリアル工学II

    2016

  22. 物理化学B

    2016

  23. 基礎セミナーA

    2016

  24. 材料工学序論

    2015

  25. 材料工学実験基礎

    2015

  26. 材料工学実験第2

    2015

  27. マテリアル工学2

    2015

  28. Physical Chemistry

    2015

  29. 材料工学実験基礎

    2014

  30. 材料工学序論

    2014

  31. 材料工学実験第2

    2014

  32. 材料工学実験基礎

    2013

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Social Contribution 1

  1. 理系女子進路選択支援シンポジウム

    2014.8

Academic Activities 1

  1. 女子のための理系きっかけフェスタ

    愛知県  ( 名古屋大学・ウィルあいち ) 2017.10 - 2017.11