論文 - 兒玉 哲也
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Benzylidene acetal-type bridged nucleic acids: changes in properties upon cleavage of the bridge triggered by external stimuli. 査読有り
Kunihiko Morihiro, Tetsuya Kodama, Satoshi Obika
Chemistry - A European Journal 17 巻 ( 28 ) 頁： 7918–7926 2011年6月
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Bridged nucleic acid conjugates at 6'-thiol: synthesis, hybridization properties and nuclease resistances. 査読有り
Kazuto Mori, Tetsuya Kodama, Takeshi Baba, Satoshi Obika.
Organic &. Biomolecular Chemistry 9 巻 ( 14 ) 頁： 5272-5279 2011年4月
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外部刺激応答型人工核酸スイッチの設計と合成. 査読有り
兒玉哲也
131 巻 ( 1 ) 頁： 101-111 2011年1月
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架橋型人工核酸BNAの開発（４）：外部刺激応答型人工核酸スイッチへの展開 査読有り
兒玉哲也, 今西武, 小比賀聡
14 巻 ( 2 ) 頁： 35-44 2010年12月
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A novel bridged nucleoside bearing a conformationally switchable sugar moiety in response to redox changes 査読有り
Takeshi Baba, Tetsuya Kodama, Kazuto Mori, Takeshi Imanishi, and Satoshi Obika.
Chemical Communications 46 巻 頁： 8058-8060. 2010年9月
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Double-stranded DNA-templated cleavage of oligonucleotides containing a P3'->N5' linkage triggered by triplex formation: the effects of chemical modifications and remarkable enhancement in reactivity. 査読有り
Kosuke Ramon Ito, Tetsuya Kodama, Masaharu Tomizu, Yoshinori Negoro, Ayako Orita, Tomohisa Osaki, Noritsugu Hosoki, Takaya Tanaka, Takeshi Imanishi, and Satoshi Obika.
Nucleic Acids Research 38 巻 ( 20 ) 頁： 7332-7342. 2010年7月
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Synthesis, RNA selective hybridization and high nuclease resistance of an oligonucleotide containing novel bridged nucleic acid with cyclic urea structure. 査読有り
Masaru Nishida, Takeshi Baba, Tetsuya Kodama, Aiko Yahara, Takeshi Imanishi, and Satoshi Obika.
Chemical Communications 46 巻 ( 29 ) 頁： 5283-5285 2010年6月
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Synthesis and evaluation of novel 3,4-epoxypiperidines as efficient DNA alkylating agents. 査読有り
Yuji Kawada, Tetsuya Kodama, Kazuyuki Miyashita, Takeshi Imanishi, and Satoshi Obika.
Heterocycles 80 巻 ( 2 ) 頁： 1249-1265 2009年10月
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Development of light-responsive BNA toward the spatiotemporal control of gene expression.
Kunihiko Morihiro, Tetsuya Kodama, Masaru Nishida, Takeshi Imanishi, and Satoshi Obika.
Nucleic Acids Symp Ser 53 巻 頁： 187-188 2009年9月
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Synthesis and properties of a novel 2',4'-BNA bearing a urea bridged structure.
Aiko Yahara, Masaru Nishida, Takeshi Baba, Tetsuya Kodama, Takeshi Imanishi, and Satoshi Obika.
Nucleic Acids Symp Ser 53 巻 頁： 11-12 2009年9月
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Synthesis and properties of a novel artificial nucleoside that acts as a redox switch.
Takeshi Baba, Tetsuya Kodama, Takeshi Imanishi, and Satoshi Obika.
Nucleic Acids Symp Ser 53 巻 頁： 107-108 2009年9月
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Synthesis of light-responsive bridged nucleic acid and changes in affinity with complementary ssRNA. 査読有り
Kunihiko Morihiro, Tetsuya Kodama, Masaru Nishida, Takeshi Imanishi and Satoshi Obika.
ChemBioChem 10 巻 ( 11 ) 頁： 1784-1788 2009年7月
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A bridged nucleic acid, 2',4'-BNACOC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNACOC monomers, and RNA-selective nucleic acid recognition. 査読有り
Yasunori Mitsuoka, Tetsuya Kodama, Ryo Ohnishi, Yoshiyuki Hari, Takeshi Imanishi and Satoshi Obika.
Nucleic Acids Research 37 巻 ( 4 ) 頁： 1225-1238 2009年1月
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Design, synthesis, and evaluation of a novel bridged nucleic acid, 2',5'-BNAON, with S-type sugar conformation fixed by N-O linkage. 査読有り
Tetsuya Kodama, Chieko Matsuo, Hidetsugu Ori, Tetsuya Miyoshi, Satoshi Obika, Kazuyuki Miyashita, Takeshi Imanishi.
Tetrahedron 65 巻 ( 10 ) 頁： 2116-2123 2008年12月
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Synthesis of a novel trans-3',4'-BNA monomer bearing a 4,8-dioxa-5-azabicyclo[5.3.0]decane skeleton. 査読有り
Tetsuya Kodama, Kensaku Sugaya, Takeshi Baba, Takeshi Imanishi and Satoshi Obika.
Heterocycles 79 巻 ( 1 ) 頁： 873-882 2008年11月
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Synthesis and properties of 2'-deoxy-trans-3',4'-BNA with S-type sugar puckering. 査読有り
Tetsuya Kodama, Kensaku Sugaya, Yasuki Harada, Yasunori Mitsuoka, Takeshi Imanishi and Satoshi Obika.
Heterocycles 77 巻 頁： 1209-1217 2008年10月
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Design and Chemical Synthesis of a 2',4'-BNA Probe for 7,8-Dihydro-8-oxoguanine-containing Double Stranded DNA.
Tetsuya Miyoshi, Tetsuya Kodama, Satoshi Obika and Takeshi Imanishi.
Nucleic Acids Symp Ser 52 巻 頁： 305-306 2008年9月
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二リン酸ジエステル結合で連なるDNA. 査読有り
兒玉哲也
ファルマシア 44 巻 ( 1 ) 頁： 71-72 2008年4月
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Synthesis and evaluation of a novel 2',5'-bridged nucleic acid with sugar conformation fixed to S-type by N-O linkage.
Tetsuya Kodama, Chieko Matsuo, Hidetsugu Ori, Satoshi Obika, Kazuyuki Miyashita, Takeshi Imanishi.
Nucleic Acids Symp Ser 51 巻 頁： 159-160 2007年11月
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Synthesis and properties of a 2'-deoxy analogue of trans-3',4'-BNA with an S-type sugar conformation.
Kensaku Sugaya, Y. Harada, Yasunori Mitsuoka, Tomohisa Osaki, Satoshi Obika, Tetsuya Kodama, Takeshi Imanishi.
Nucleic Acids Symp Ser 51 巻 頁： 155-156 2007年11月