Updated on 2024/10/31

写真a

 
KIMURA Makoto
 
Organization
Graduate School of Bioagricultural Sciences Department of Applied Biosciences Professor
Graduate School
Graduate School of Bioagricultural Sciences
Undergraduate School
School of Agricultural Sciences Department of Applied Biosciences
Title
Professor

Degree 1

  1. 博士(農学) ( 1995.12   東京大学 ) 

Research Interests 6

  1. 応用微生物学

  2. 食の安全

  3. 植物保護

  4. 二次代謝

  5. 物質生産

  6. 酵素

Research Areas 2

  1. Life Science / Applied microbiology

  2. Environmental Science/Agriculture Science / Plant protection science

Current Research Project and SDGs 2

  1. 作物細胞壁の微生物分解と発酵に関する研究

  2. 糸状菌の二次代謝制御に関する研究

Research History 11

  1. 名古屋大学大学院生命農学研究科  教授

    2021.5

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    Country:Japan

  2. 名古屋大学大学院生命農学研究科  准教授

    2011.8 - 2021.4

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    Country:Japan

  3. 明治大学農学部 兼任講師

    2010.4 - 2011.9

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    Country:Japan

  4. 茨城大学農学部 非常勤講師

    2008.10 - 2009.9

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    Country:Japan

  5. 理化学研究所基幹研究所 専任研究員

    2008.4 - 2011.7

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    Country:Japan

  6. 理化学研究所中央研究所 研究ユニットリーダー

    2005.8 - 2008.3

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    Country:Japan

  7. 理化学研究所 先任研究員

    2003.4 - 2008.3

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    Country:Japan

  8. 理化学研究所植物科学研究センター サブチームリーダー

    2000.4 - 2005.3

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    Country:Japan

  9. カリフォルニア州立大学バークレー校(Department of Plant & Microbial Biology)リサーチフェロー

    1998.9 - 2000.3

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    Country:United States

  10. 理化学研究所 研究員

    1996.4 - 2003.3

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    Country:Japan

  11. 理化学研究所 研究員補

    1991.4 - 1996.3

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    Country:Japan

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Education 2

  1. The University of Tokyo   Graduate School, Division of Agricultural Science

    - 1991.3

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    Country: Japan

  2. The University of Tokyo   Faculty of Agriculture

    - 1989.3

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    Country: Japan

Professional Memberships 3

  1. Fungal Molecular Biology Society of Japan

    2008.1

  2. Japanese Society for Mycotoxicology

    2003.12

  3. Japan Society for Bioscience, Biotechnology, and Agrochemistry

    1990.1

Committee Memberships 8

  1. 日本マイコトキシン学会   会長  

    2024.1   

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    Committee type:Academic society

  2. 日本農芸化学会   英文誌編集委員  

    2023.3   

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    Committee type:Academic society

  3. 日本農芸化学会   代議員  

    2022.5   

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    Committee type:Academic society

  4. 日本マイコトキシン学会   会長補佐  

    2020.1 - 2023.12   

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    Committee type:Academic society

  5. 日本農芸化学会   中部支部選挙管理委員  

    2017.9 - 2018.5   

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    Committee type:Academic society

  6. 日本農芸化学会   大会実行委員  

    2016.12 - 2019.2   

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    Committee type:Academic society

  7. 日本農芸化学会   中部支部庶務幹事  

    2016.5 - 2018.5   

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    Committee type:Academic society

  8. 日本マイコトキシン学会   幹事  

    2010.1   

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    Committee type:Academic society

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Awards 1

  1. 日本農芸化学会奨励賞

    2005.3   日本農芸化学会  

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    Country:Japan

 

Papers 121

  1. Attempting to create a pathway to 15-deacetylcalonectrin with limited accumulation in cultures of Fusarium Tri3 mutants: insight into trichothecene biosynthesis machinery Reviewed International journal

    Kasahara E, Kitamura Y, Katada M, Mizuki M, Okumura N, Sano T, Koizumi Y, Maeda K, Takahashi-Ando N, Kimura M, Nakajima Y

    International Journal of Molecular Sciences   Vol. 25 ( 12 ) page: 6414   2024.6

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms25126414

    DOI: 10.3390/ijms25126414

    Other Link: https://www.mdpi.com/journal/ijms

  2. A role in 15-deacetylcalonectrin acetylation in the non-enzymatic cyclization of an earlier bicyclic intermediate in Fusarium trichothecene biosynthesis Reviewed International journal

    Koizumi Y, Nakajima Y, Tanaka Y, Matsui K, Sakabe M, Maeda K, Sato M, Koshino H, Sato S, Kimura M, Takahashi-Ando N

    International Journal of Molecular Sciences   Vol. 25 ( 8 ) page: 4288   2024.4

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms25084288

    DOI: 10.3390/ijms25084288

    Other Link: https://www.mdpi.com/journal/ijms

  3. Microorganisms and their metabolism affecting quality, safety and functionality of agricultural products Reviewed International journal

    Liew MXX, Nakajima Y, Maeda K, Kitamura N, Kimura M

    Frontiers in Microbiology   Vol. 14   page: 1148771   2023.5

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fmicb.2023.1215112

    DOI: 10.3389/fmicb.2023.1215112

    Other Link: https://www.frontiersin.org/journals/microbiology

  4. Regulatory mechanism of trichothecene biosynthesis in Fusarium graminearum Reviewed International journal

    Liew MXX, Nakajima Y, Maeda K, Kitamura N, Kimura M

    Frontiers in Microbiology   Vol. 14   page: 1148771   2023.4

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fmicb.2023.1148771

    DOI: 10.3389/fmicb.2023.1148771

    Other Link: https://www.frontiersin.org/journals/microbiology

  5. Synergistic effect of amino acid substitutions in CYP51B for prochloraz resistance in Fusarium fujikuroi Reviewed International journal

    Li F, Ebihara A, Sakahara Y, Matsumoto S, Ueno R, Bao W, Kimura M, Fuji S, Shimizu M, Kageyama K, Suga H

    Pesticide Biochemistry and Physiology   Vol. 189   page: 105291   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.pestbp.2022.105291

    DOI: 10.1016/j.pestbp.2022.105291

    Other Link: https://www.sciencedirect.com/journal/pesticide-biochemistry-and-physiology

  6. cAMP signaling factors regulate carbon catabolite repression of hemicellulase genes in Aspergillus nidulans Reviewed International journal

    Kunitake E, Uchida R, Asano K, Kanamaru K, Kimura M, Kimura T, Kobayashi T

    AMB Express   Vol. 12   page: 126   2022.10

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s13568-022-01467-x

    DOI: 10.1186/s13568-022-01467-x

    Other Link: https://amb-express.springeropen.com/

  7. Generation of mitochondrial reactive oxygen species through a histidine kinase, HysA in Aspergillus nidulans Reviewed

    Kanamaru K, Izuhara K, Kimura M, Kobayashi T

    Journal of General and Applied Microbiology   Vol. 68   page: 17 - 23   2022.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2323/jgam.2021.09.001

    DOI: 10.2323/jgam.2021.09.001

    Other Link: https://www.jstage.jst.go.jp/browse/jgam/-char/en

  8. First report of Fusarium armeniacum isolated from rice in Aichi Prefecture. Reviewed

    Sano T, Mizuki, M, Matsui, K, Takahashi-Ando, N, Kimura, M, and Nakajima, Y

    JSM Mycotoxins   Vol. 72 ( 1 ) page: 1 - 3   2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.72-1-1

    DOI: 10.2520/myco.72-1-1

    Other Link: https://www.jstage.jst.go.jp/browse/myco/-char/en

  9. 4-O-glucosylation of trichothecenes by Fusarium species: a phase II xenobiotic metabolism for t-type trichothecene producers. Reviewed International journal

    Matsui, K, Takeda, H, Shinkai, K, Kakinuma, T, Koizumi, Y, Kase, M, Yoshinari, T, Minegishi, H, Nakajima, Y, Aikawa, S, Takahashi-Ando, N, and Kimura, M

    International Journal of Molecular Sciences   Vol. 22   page: 13542   2021.12

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms222413542

    DOI: 10.3390/ijms222413542

    Other Link: https://www.mdpi.com/journal/ijms

  10. Accumulation of 4-deoxy-7-hydroxytrichothecenes, but not 4,7-dihydroxytrichothecenes, in axenic culture of a transgenic nivalenol chemotype expressing the NX-type FgTri1 gene. Reviewed International journal

    Maeda K, Nakajima Y, Koizumi Y, Takahashi-Ando N, Kimura M, and Ohsato S

    International Journal of Molecular Sciences   Vol. 22   page: 11428   2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms222111428

    DOI: 10.3390/ijms222111428

    Other Link: https://www.mdpi.com/journal/ijms

  11. Nicotinamide mononucleotide potentiates resistance to biotrophic invasion of fungal pathogens in barley. Reviewed International journal

    Ueda K, Nakajima Y, Inoue H, Kobayashi K, Nishiuchi T, Kimura M, and Yaeno T

    International Journal of Molecular Sciences   Vol. 22   page: 2696   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms22052696

    Other Link: https://www.mdpi.com/journal/ijms

  12. Nicotinamide effectively suppresses Fusarium Head Blight in wheat plants. Reviewed International journal

    Sidiq Y, Nakano M, Mori Y. Yaeno T. Kimura M, and Nishiuchi T

    International Journal of Molecular Sciences   Vol. 22   page: 2968   2021.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms22062968

    DOI: 10.3390/ijms22062968

    Other Link: https://www.mdpi.com/journal/ijms

  13. Synthetic liquid media for the study of trichothecene biosynthesis regulation in Fusarium graminearum. Reviewed

    Nakao, A, Nakajima, Y, Akasaka, M, Kitou Y, Maeda, K, Kanamaru, K, Kobayashi, T, and Kimura, M

    JSM Mycotoxins   Vol. 70 ( 2 ) page: 59-61   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.70-2-6

  14. Impact of nitrogen metabolism-associated culture pH changes on regulation of Fusarium trichothecene biosynthesis: revision of roles of polyamine agmatine and transcription factor AreA. Reviewed International journal

    Nakajima, Y, Akasaka, M, Shiobara, T, Kitou Y, Maeda, K, Kanamaru, K, Ohsato, S, Kobayashi, T, Nishiuchi, T, and Kimura, M

    Current Genetics   Vol. 66 ( 6 ) page: 1179–1190   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00294-020-01102-x

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  15. Substrate specificities of Fusarium biosynthetic enzymes explain the genetic basis of a mixed chemotype producing both deoxynivalenol and nivalenol-type trichothecenes. Reviewed

    Maeda K, Tanaka Y, Matsuyama M, Sato M, Sadamatsu K, Suzuki T, Matsui K, Nakajima Y, Tokai T, Kanamaru K, Ohsato S, Kobayashi T, Fujimura M, Nishiuchi T, Takahashi-Ando N, and Kimura M

    International Journal of Food Microbiology   Vol. 320   page: 108532   2020.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ijfoodmicro.2020.108532

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  16. Reduced toxicity of trichothecenes, isotrichodermol, and deoxynivalenol, by transgenic expression of the Tri101 3-O-acetyltransferase gene in cultured mammalian FM3A cells. Reviewed

    Tanaka N, Takushima R, Tanaka A, Okada A,Matsui K, Maeda K, Aikawa S, Kimura M, and Takahashi-Ando N

    Toxins   Vol. 11   page: 654   2019.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/toxins11110654

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  17. Identification of amino acids negatively affecting Fusarium trichothecene biosynthesis. Reviewed

    Shiobara T, Nakajima Y, Maeda K, Akasaka M, Kitou Y, Kanamaru K, Kobayashi T, Nishiuchi T, and Kimura M

    Antonie van Leeuwenhoek   Vol. 112 ( 3 ) page: 471-478   2019.3

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  18. Comparison of HPLC-UV and LC-MS methods for evaluating the amount of deoxynivalenol-type trichothecenes in axenic solid culture of Fusarium graminearum. Reviewed

    Tanaka A, Shinkai K, Maeda K, Nakajima Y, Ishii S, Yoshida S, Kimura M, Takahashi-Ando N

    JSM Mycotoxins   Vol. 69 ( 1 ) page: 15-17   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.69-1-2

  19. Inhibition of Fusarium trichothecene biosynthesis by yeast extract components extractable with ethyl acetate. Reviewed

    Tanaka Y, Nakajima Y, Maeda K, Matsuyama M, Kanamaru K, Kobayashi T, Ohsato S, and Kimura M

    International Journal of Food Microbiology   Vol. 280   page: 24-29   2019.1

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  20. Comparison of the paralogous transcription factors AraR and XlnR in Aspergillus oryzae. Reviewed

    Ishikawa K, Kunitake E, Kawase T, Atsumi M, Noguchi Y, Ishikawa S, Ogawa M, Koyama Y, Kimura M, Kanamaru K, Kato M, and Kobayashi T

    Current Genetics   Vol. 64   page: 1245-1260   2018.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00294-018-0837-5

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  21. Exploring an artificial metabolic route in Fusarium sporotrichioides: production and characterization of 7-hydroxy T-2 toxin. Reviewed

    Kamata K, Sato H, Maeda K, Furihata K, Aikawa S, Adachi K, Tanaka A, Tokai T, Nakajima Y, Yoshida Y, Sakuda S, Kimura M, and Takahashi-Ando N

    Journal of Natural Products   Vol. 81 ( 4 ) page: 1041-1044   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.jnatprod.7b00398

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  22. Identification and characterization of small molecule compounds that modulate trichothecene production by Fusarium graminearum. Reviewed

    Maeda K, Ichikawa H, Nakajima Y, Motoyama T, Ohsato S, Kanamaru K, Kobayashi T, Nishiuchi T, Osada H, and Kimura M

    ACS Chemical Biology   Vol. 13 ( 5 ) page: 1260-1269   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acschembio.8b00044

    Research data storage URL: https://nagoya.repo.nii.ac.jp/?action=repository_uri&item_id=26379

    PubMed

  23. Increased metabolite production by deletion of an HDA1-type histone deacetylase in the phytopathogenic fungi, Magnaporthe oryzae (Pyricularia oryzae) and Fusarium asiaticum. Reviewed

    Maeda K, Izawa M, Nakajima Y, Jin Q, Hirose T, Nakamura T, Koshino H, Kanamaru K, Ohsato S, Kamakura T, Kobayashi T, Yoshida M, and Kimura M

    Letters in Applied Microbiology   Vol. 65 ( 5 ) page: 446-452   2017.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/lam.12797

    Research data storage URL: https://nagoya.repo.nii.ac.jp/?action=repository_uri&item_id=26380

    PubMed

  24. L-Threonine and its analogue added to autoclaved solid medium suppress trichothecene production by Fusarium graminearum. Reviewed

    Maeda K, Nakajima Y, Tanahashi Y, Kitou Y, Miwa A, Kanamaru K, Kobayashi T, Nishiuchi T, and Kimura M

    Archives of Microbiology   Vol. 199 ( 6 ) page: 945-952   2017.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00203-017-1364-3

    Research data storage URL: https://nagoya.repo.nii.ac.jp/?action=repository_uri&item_id=24775

    PubMed

  25. Nicotinamide mononucleotide and related metabolites induce disease resistance against fungal phytopathogens in Arabidopsis and barley. Reviewed

    Miwa A, Sawada Y, Tamaoki D, Yokota-Hirai M, Kimura M, Sato K, and Nishiuchi T

    Scientific Reports   Vol. 7 ( 1 ) page: 6389   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-017-06048-8

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  26. Identification of a trichothecene production inhibitor by chemical array and library screening using trichodiene synthase as a target protein. Reviewed

    Maeda K, Nakajima Y, Motoyama T, Kondoh Y, Kawamura T, Kanamaru K, Ohsato S, Nishiuchi T, Yoshida M, Osada H, Kobayashi T, and Kimura M

    Pesticide Biochemistry and Physiology   Vol. 138   page: 1-7   2017.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.pestbp.2017.03.006

    Research data storage URL: https://nagoya.repo.nii.ac.jp/?action=repository_uri&item_id=26381

    PubMed

  27. Accumulation of an unusual trichothecene shunt metabolite in liquid culture of Fusarium graminearum with methionine as the sole nitrogen source. Reviewed

    Nakajima Y, Tanaka Y, Matsui K, Maeda K, Kitou Y, Kanamaru K, Ohsato S, Kobayashi T, Takahashi-Ando N, and Kimura M

    JSM Mycotoxins   Vol. 67 ( 1 ) page: 7-9   2017.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.67-1-9

  28. Acetyltransferase activity in Pseudomonas sp. capable of acetylating the C-4 hydroxyl group of nivalenol-type trichothecenes.

    Tanaka A, Saikawa S, Suzuki T, Echigo A, Maeda K, Sato M, Fujimura M, Tokai T, Usami R, Yoshida Y, Kimura M, and Takahashi-Ando N

    Journal of General and Applied Microbiology   Vol. 62 ( 6 ) page: 326-329   2016.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2323/jgam.2016.05.002

    PubMed

  29. McmA-dependent and -independent regulatory systems governing expression of ClrB-regulated cellulase and hemicellulase genes in Aspergillus nidulans. Reviewed

    Li N, Kunitake E, Aoyama M, Ogawa M, Kanamaru K, Kimura M, Koyama Y, and Kobayashi T

    Molecular Microbiology   Vol. 102 ( 5 ) page: 810-826   2016.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/mmi.13493

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  30. Oligosaccharides containing an α-(1→2) (glucosyl/xylosyl)-fructosyl linkage as inducer molecules of trichothecene biosynthesis for Fusarium graminearum.

    Nakajima Y, Maeda K, Jin Q, Takahashi-Ando N, Kanamaru K, Kobayashi T, and Kimura M

    International Journal of Food Microbiology   Vol. 218   page: 215-221   2016.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ijfoodmicro.2016.09.011

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  31. Characterization of the acivicin effects on trichothecene production by Fusarium graminearum species complex.

    Maeda K, Nakajima Y, Tanahashi Y, Kosaki T, Kitou Y, Kanamaru K, Kobayashi T, Nishiuchi T, and Kimura M

    Journal of General and Applied Microbiology   Vol. 62 ( 5 ) page: 272-276   2016.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2323/jgam.2016.04.002

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  32. Hydroxylations of trichothecene rings in the biosynthesis of Fusarium trichothecenes: evolution of alternative pathways in the nivalenol chemotype. Reviewed

    Maeda K, Tanaka A, Sugiura R, Koshino H, Tokai T, Sato M, Tanahashi Y, Nakajima Y, Kanamaru K, Kobayashi T, Nishiuchi T, Fujimura M, Takahashi-Ando N, and Kimura M

    Environmental Microbiology   Vol. 18 ( 11 ) page: 3798-3811   2016.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/1462-2920.13338

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  33. Involvement of an SRF-MADS protein McmA in regulation of extracellular enzyme production and asexual/sexual development in Aspergillus nidulans.

    Bioscience, Biotechnology, and Biochemistry   Vol. 80 ( 9 ) page: 1820-1828   2016.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/09168451.2016.1146074

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  34. Regulation of genes encoding cellulolytic enzymes by Pal-PacC signaling in Aspergillus nidulans.

    Kunitake E, Hagiwara D, Miyamoto K, Kanamaru K, Kimura M, and Kobayashi T

    Applied Microbiology and Biotechnology   Vol. 100 ( 8 ) page: 3621-3635   2016.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00253-016-7409-8

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  35. Re-examination of genetic and nutritional factors related to trichothecene biosynthesis in Fusarium graminearum. Reviewed

    Kitou Y, Nakajima Y, Maeda K, Jin Q, Nishiuchi T, Kanamaru K, Kobayashi T, and Kimura M

    Bioscience, Biotechnology, and Biochemistry   Vol. 80 ( 2 ) page: 414-417   2016.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/09168451.2015.1088374

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  36. Trichothecene production in axenic liquid culture of Fusarium graminearum using xylose as a carbon source.

    Kitou Y, Kosaki T, Maeda K, Tanahashi K, Nakajima Y, Kanamaru K, Kobayashi T, and Kimura M

    JSM Mycotoxins   Vol. 66 ( 1 ) page: 17-19   2016.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.66.17

  37. Nuclear localization and relative stability of the zinc finger domain of TRI6 trichothecene regulator. Reviewed

    Nakajima Y, Maeda M, Ohsato S, Kanamaru K, Kobayashi T, and Kimura M

    JSM Mycotoxins   Vol. 66 ( 1 ) page: 13-15   2016.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.66.13

  38. Introduction of a leptomycin-sensitive mutation into Fusarium graminearum.

    Nakajima Y, Maeda K, Ohsato S, Kanamaru K, Kobayashi T, and Kimura M

    JSM Mycotoxins   Vol. 66 ( 1 ) page: 9-11   2016.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2520/myco.66.9

  39. 2,4-Dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA) inhibits trichothecene production by Fusarium graminearum through suppression of Tri6 expression.

    Etzerodt T, Maeda K, Nakajima Y, Laursen, B., Fomsgaard, I.S., and Kimura M

    International Journal of Food Microbiology   Vol. 214   page: 123-128   2015.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.ijfoodmicro.2015.07.014

    PubMed

  40. Precocene II, a trichothecene production inhibitor, binds to voltage-dependent anion channel and increases the superoxide level in mitochondria of Fusarium graminearum.

    Furukawa K, Sakamoto N, Suzuki M, Kimura M, Nagasawa H, and Sakuda S

    PLoS One   Vol. 10   page: e0135031   2015.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1371/journal.pone.0135031

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  41. Effect of disrupting the trichothecene efflux pump encoded by FgTri12 in the nivalenol chemotype of Fusarium graminearum. Reviewed

    Nakajima Y, Koseki N, Sugiura R, Tominaga N, Maeda K, Tokai T, Izawa M, Kanamaru K, Kobayashi T, Nishiuchi T, Yoshida M, and Kimura M

    Journal of General and Applied Microbiology   Vol. 61 ( 3 ) page: 93-96   2015.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.2323/jgam.61.93

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  42. Evaluation of toxicities of 7-hydroxyisotrichodermin and 8-hydroxyisotrichodermin, shunt intermediates in the biosynthetic grid of deoxynivalenol, by using a sensitive yeast assay. Reviewed

    Kamata K, Tanaka A, Maeda K, Takushima R, Sato H, Aikawa S, Yoshida Y, Kimura M, and Takahashi-Ando N

    JSM Mycotoxins   Vol. 65 ( 1 ) page: 7-9   2015.1

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    DOI: 10.2520/myco.65.7

  43. Effects of acivicin on growth, mycotoxin production and virulence of phytopathogenic fungi. Reviewed

    Maeda K, Nakajima Y, Motoyama T, Kitou Y, Kosaki T, Saito T, Nishiuchi T, Kanamaru K, Osada H, Kobayashi T, and Kimura M

    Letters in Applied Microbiology   Vol. 59 ( 4 ) page: 377-383   2014.10

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    DOI: 10.1111/lam.12289

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  44. A set of heterologous promoters useful for investigating gene functions in Fusarium graminearum. Reviewed

    Nakajima Y, Tokai T, Maeda K, Tanaka A, Takahashi-Ando N, Kanamaru K, Kobayashi T, and Kimura M

    JSM Mycotoxins   Vol. 64 ( 2 ) page: 147-152   2014.7

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    DOI: 10.2520/myco.64.147

  45. Site-specific DNA double-strand break generated by I-SceI endonuclease enhances ectopic homologous recombination in Pyricularia oryzae. Reviewed

    Arazoe T, Younomaru T, Ohsato S, Kimura M, Arie T, and Kuwata S.

    FEMS Microbiology Letters   Vol. 352 ( 2 ) page: 221-229   2014.3

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    DOI: 10.1111/1574-6968.12396

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  46. Identification and characterization of an inhibitor of trichothecene 3-O-acetyltransferase, TRI101, by the chemical array approach. Reviewed

    Nakajima Y, Kawamura, T, Maeda K, Ichikawa H, Motoyama T, Kondo Y, Saito T, Kobayashi T, Yoshida M, Osada H, and Kimura M.

    Bioscience, Biotechnology, and Biochemistry   Vol. 77 ( 9 ) page: 1958--1960   2013.9

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    DOI: 10.1271/bbb.130153

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  47. A promoter of Fusarium graminearum Tri4 does not function when placed at the end of the trichothecene gene cluster. Reviewed

    Tokai T, Nakajima Y, Ichikawa H, Maeda K, Nishiuchi T, Kobayashi T, and Kimura M.

    Mycotoxins   Vol. 63 ( 1 ) page: 17-25   2013

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    DOI: 10.2520/myco.63.17

  48. The secreted antifungal protein thionin 2.4 in Arabidopsis thaliana suppresses the toxicity of fungal fruit body lectin from Fusarium graminearum.

    Asano T, Miwa A, Maeda K, Kimura M, and Nishiuchi T.

    PLoS Pathogens   Vol. 9   page: e1003581   2013

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    DOI: 10.1371/journal.ppat.1003581

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  49. Production of 3-acetylnivalenol by transgenic Fusarium graminearum expressing Tri13 of type A trichothecene-producer: participation of the encoded cytochrome P450 monooxygenase in type B trichothecene biosynthesis.

    Maeda K, Tokai T, Ichikawa H, Takahashi-Ando N, Ogura N, Yoneyama K, Yoshida M, and Kimura M.

    Mycotoxins   Vol. 62 ( 2 ) page: 83-90   2012

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    DOI: 10.2520/myco.62.83

  50. The defense response in Arabidopsis thaliana against Fusarium sporotrichioides. Reviewed

    Asano T, Kimura M, and Nishiuchi T.

    Proteome Science   Vol. 10   page: 61. doi:10.1186/1477-5956-10-61   2012

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    DOI: 10.1186/1477-5956-10-61

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  51. Development of a simultaneous liquid chromatography/tandem mass spectrometric method for the determination of type B trichothecenes, their derivatives, and precursors in wheat. Reviewed

    Kadota T, Kimura M, Hirano S, Tajima O, Nakajima T, Kamata Y, and Sugita-Konishi Y

    Rapid Communications in Mass Spectrometry   Vol. 25 ( 23 ) page: 3481-3490   2011

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    DOI: 10.1002/rcm.5250

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  52. Characterization of QoI resistance in Botrytis cinerea and identification of two types of mitochondrial cytochrome b gene. Reviewed

    Banno S, Yamashita K, Fukumori F, Okada K, Uekusa H, Takagaki M, Kimura M, and Fujimura M.

    Plant Pathol.   Vol. 58   page: 120-129   2009

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  53. Inhibition of histone deacetylase causes reduction of appressorium formation in the rice blast fungus Magnaporthe oryzae. Reviewed

    Izawa M, Takekawa O, Arie T, Teraoka T, Yoshida M, Kimura M, and Kamakura T.

    J. Gen. Appl. Microbiol.   Vol. 55   page: 489-498   2009

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  54. 4-O-Acetylation and 3-O-acetylation of trichothecenes by trichothecene 15-O-acetyltransferase encoded by Fusarium Tri3. Reviewed

    Tokai T, Takahashi-Ando N, Izawa M, Kamakura T, Yoshida M, Fujimura M, and Kimura M.

    Biosci. Biotechnol. Biochem.   Vol. 72 ( 9 ) page: 2485-2489   2008.9

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  55. AtNFXL1, an Arabidopsis homologue of the human transcription factor NF-X1, functions as a negative regulator of the trichothecene phytotoxin-induced defense response. Reviewed

    Asano T, Masuda D, Yasuda M, Nakashita H, Kudo T, Kimura M, Yamaguchi K, and Nishiuchi T.

    Plant J.   Vol. 53   page: 450-464   2008

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  56. Genotyping of benzimidazole-resistant and dicarboximide-resistant mutations in Botrytis cinerea using real-time polymerase chain reaction assays.

    Banno S, Fukumori F, Ichiishi A, Okada K, Uekusa H, Kimura M, and Fujimura M.

    Phytopathology   Vol. 98   page: 397-404   2008

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  57. ATF-1 transcription factor regulates the expression of ccg-1 and cat-1 genes in response to osmotic stress in Neurospora crassa. Reviewed

    Yamashita K, Shiozawa A, Watanabe S, Fukumori F, Kimura M, and Fujimura M.

    Fungal Genet. Biol.   Vol. 45   page: 1562-1569   2008

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  58. Multilocus genotyping and molecular phylogenetics resolve a novel head blight pathogen within the Fusarium graminearum species complex from Ethiopia.

    O'Donnell K, Ward TJ, Aberra D, Kistler HC, Aoki T, Orwig N, Kimura M, Bjørnstad Å, and Klemsdal SS.

    Fungal Genet. Biol.   Vol. 45   page: 1514-1522   2008

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  59. The AtNFXL1 gene functions as a signaling component of the type A trichothecene-dependent response.

    Asano T, Yasuda M, Nakashita H, Kimura M, Yamaguchi K and Nishiuchi T.

    Plant Signal Behav.   Vol. 3   page: 991-992   2008

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  60. An easy method to identify 8-keto-15-hydroxytrichothecenes by thin-layer chromatography. Reviewed

    Takahashi-Ando N, Tokai T, Yoshida M, Fujimura M, and Kimura M.

    Mycotoxins   Vol. 58   page: 115-117   2008

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  61. Spiroethers of German chamomile inhibit production of aflatoxin G1 and trichothecene mycotoxin by inhibiting cytochrome P450 monooxygenases involved in their biosynthesis. Reviewed

    Yoshinari T, Yaguchi A, Takahashi-Ando N, Kimura M, Takahashi H, Nakajima T, Sugita-Konishi Y, Nagasawa H, and Sakuda S.

    FEMS Microbiol. Lett.   Vol. 284   page: 184-190   2008

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  62. A screening system for inhibitors of trichothecene biosynthesis: hydroxylation of trichodiene as a target. Reviewed

    Takahashi-Ando N, Ochiai N, Tokai T, Ohsato S, Nishiuchi T, Yoshida M, Fujimura M, and Kimura M.

    Biotechnol. Lett.   Vol. 30   page: 1055-1059   2008

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  63. OS-2 mitogen activated protein kinase regulates the clock-controlled gene ccg-1 in Neurospora crassa. Reviewed

    Watanabe S, Yamashita K, Ochiai N, Fukumori F, Ichiishi A, Kimura M and Fujimura M.

    Biosci. Biotechnol. Biochem.   Vol. 71 ( 11 ) page: 2856-2859   2007.11

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  64. Molecular and genetic studies of Fusarium trichothecene biosynthesis: pathways, genes, and evolution. Invited Reviewed

      Vol. 71 ( 9 ) page: 2105-2123   2007.9

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  65. Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis. Reviewed

    Tokai T, Koshino H, Takahashi-Ando N, Sato M, Fujimura M, and Kimura M.

    Biochem. Biophys. Res. Commun.   Vol. 353   page: 412-417   2007

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  66. Crystal structures of blasticidin S deaminase (BSD): implications for dynamic properties of catalytic zinc. Reviewed

    Kumasaka T, Yamamoto M, Furuichi M, Nakasako M, Teh A-H, Kimura M, Yamaguchi I, and Ueki T.

    J. Biol. Chem.   Vol. 282   page: 37103-37111   2007

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  67. Involvement of the osmosensor histidine kinase and osmotic stress-activated protein kinases in the regulation of secondary metabolism in Fusarium graminearum.

    Ochiai N, Tokai T, Nishiuchi T, Takahashi-Ando N, Fujimura M, and Kimura M.

    Biochem. Biophys. Res. Commun.   Vol. 363   page: 639-644   2007

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  68. Involvement of OS-2 MAP kinase in regulation of the large-subunit catalases CAT-1 and CAT-3 in Neurospora crassa. Reviewed

    Yamashita K, Shiozawa A, Banno S, Fukumori F, Ichiishi A, Kimura M, and Fujimura M.

    Genes Genet. Syst.   Vol. 82   page: 301-310   2007

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  69. Genetically engineered Fusarium as a tool to evaluate the effects of environmental factors on initiation of trichothecene biosynthesis. Reviewed

    Ochiai N, Tokai T, Takahashi-Ando N, Fujimura M, and Kimura M.

    FEMS Microbiol. Lett.   Vol. 275   page: 53-61   2007

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  70. Identification of multiple highly similar XIP-type xylanase inhibitor genes in hexaploid wheat.

    Takahashi-Ando N, Inaba M, Ohsato S, Igawa T, Usami R, and Kimura M.

    Biochem. Biophys. Res. Commun.   Vol. 360   page: 880-884   2007

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  71. Phytotoxic effects of trichothecenes on the growth and morphology in Arabidopsis thaliana.

    Masuda D, Ishida M, Yamaguchi K, Yamaguchi I, Kimura M, and Nishiuchi T.

    J. Exp. Bot.   Vol. 58   page: 1617-1626   2007

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  72. Transgenic rice plants expressing trichothecene 3-O-acetyltransferase show resistance to the Fusarium phytotoxin deoxynivalenol.

    Ohsato S, Ochiai-Fukuda T, Takahashi-Ando N, Nishiuchi T, Koizumi S, Hamamoto H, Kudo T, Yamaguchi I, and Kimura M.

    Plant Cell Rep.   Vol. 26   page: 531-538   2007

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  73. Roles of putative His-to-Asp signaling modules HPT-1 and RRG-2, on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa. Reviewed

    Banno S, Noguchi R, Yamashita K, Fukumori F, Kimura M, Yamaguchi I, and Fujimura M.

    Curr. Genet.   Vol. 51   page: 197-208   2007

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  74. Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene. Reviewed

    Igawa T, Takahashi-Ando N, Ohsato S, Ochiai N, Shimizu T, Kudo T, Yamaguchi I, and Kimura M.

    Appl. Environ. Microbiol.   Vol. 73   page: 1622-1629   2007

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  75. Identification of OS-2 MAP kinase-dependent genes induced in response to osmotic stress, antifungal agent fludioxonil, and heat shock in Neurospora crassa. Reviewed

    Noguchi R, Banno S, Ichikawa R, Fukumori S, Ichiishi A, Kimura M, Yamaguchi I, and Fujimura M.

    Fungal Genet. Biol.   Vol. 44   page: 208-218   2007

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  76. Cloning and characterization of six highly similar endo-1,3-ß-glucanase genes in hexaploid wheat.

    Higa-Nishiyama A, Ohsato S, Banno S, Woo SH, Fujimura M, Yamaguchi I, and Kimura M.

    Plant Physiol. Biochem.   Vol. 44   page: 666-673   2006

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  77. The 1.48 Å resolution crystal structure of the homotetrameric cytidine deaminase from mouse.

    Teh AH, Kimura M, Yamamoto M, Tanaka N, Yamaguchi I, and Kumasaka T.

    Biochemistry   Vol. 45   page: 7825-7833   2006

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  78. High resolution analysis of plant growth using non-contact inkjet marking. Reviewed

    Hamamoto H, Kimura M, and Yamaguchi I.

    Exp. Environ. Bot.   Vol. 57   page: 62-69   2006

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  79. Molecular biology and biotechnology for reduction of Fusarium mycotoxin contamination.

    Kimura M, Takahashi-Ando N, Nishiuchi T, Ohsato S, Tokai T, Ochiai N, Fujimura M, Kudo T, Hamamoto H, and Yamaguchi I.

    Pestic. Biochem. Physiol.   Vol. 86   page: 117-123   2006

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  80. Conferring cadmium resistance to mature tobacco plants through metal-adsorbing particles of tomato mosaic virus vector. Reviewed

    Shingu Y, Yokomizo S, Kimura M, Ono Y, Yamaguchi I, and Hamamoto H.

    Plant Biotechnol. J.   Vol. 4   page: 281-288   2006

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  81. Fusarium phytotoxin trichothecenes have an elicitor-like activity in Arabidopsis thaliana, but the activity differed significantly among their molecular species. Reviewed

    Nishiuchi T, Masuda D, Ichimura K, Shinozaki K, Nakashita H, Yoshida S, Kimura M, Yamaguchi I, and Yamaguchi K.

    Mol. Plant-Microbe Interact.   Vol. 19   page: 512-520   2006

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  82. A fluorescent antibiotic resistance marker for rapid production of transgenic rice plants.

    Ochiai-Fukuda T, Takahashi-Ando N, Ohsato S, Igawa T, Kadokura K, Hamamoto H, Nakasako M, Kudo T, Shibata T, Yamaguchi I, and Kimura M.

    J. Biotechnol.   Vol. 122   page: 521-520   2006

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  83. Survey of mutations of a histidine kinase gene BcOs1 in dicarboximide-resistant filed isolates of Botrytis cinerea. Reviewed

    Oshima M, Banno S, Okada, K Takeuchi T, Kimura M, Ichiishi A, Yamaguchi I, and Fujimura M.

    J. Gen. Plant Pathol.   Vol. 72   page: 65-73   2006

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  84. Circumnutation of Arabidopsis thaliana inflorescence stems under light and dark conditions. Reviewed

    Someya N, Niinuma K, Kimura M, Yamaguchi I, and Hamamoto H.

    Biologia Plant.   Vol. 50   page: 287-290   2006

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  85. A wheat xylanase inhibitor gene Xip-I, but not Taxi-I, is significantly induced by biotic and abiotic signals that trigger plant defense. Reviewed

    Igawa T, Tokai T, Kudo T, Yamaguchi I, and Kimura M.

    Biosci. Biotechnol. Biochem.   Vol. 69 ( 5 ) page: 1058-1063   2005.5

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  86. Concordant evolution of trichothecene 3-O-acetyltransferase and an rDNA species phylogeny of trichothecene-producing and non-producing fusaria and other ascomycetous fungi. Reviewed

    Tokai T, Fujimura M, Inoue H, Aoki T, Ohta K, Shibata T, Yamaguchi I, and Kimura M.

    Microbiology   Vol. 151   page: 509-519   2005

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  87. Copper elicits an increase in cytosolic free calcium in cultured tobacco cells.

    Inoue H, Kudo T, Kamada H, Kimura M, Yamaguchi I, and Hamamoto H.

    Plant Physiol. Biochem.   Vol. 43   page: 1089-1094   2005

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  88. Pyrrolnitrin interferes with osmotic signal transduction in Neurospora crassa.

    Okada A, Banno S, Ichiishi A, Kimura M, Yamaguchi I, and Fujimura M.

    J. Pestic. Sci.   Vol. 30   page: 378-383   2005

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  89. A model transgenic cereal plant with detoxification activity for the estrogenic mycotoxin zearalenone. Reviewed

    Higa-Nishiyama A, Takahashi-Ando N, Shimizu T, Kudo T, Yamaguchi I, and Kimura M.

    Transgenic Res.   Vol. 14   page: 713-717   2005

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  90. Screening of putative oxygenase genes in the Fusarium graminearum genome sequence database for their role in trichothecene biosynthesis. Reviewed

    Tokai T, Koshino H, Kawasaki T, Igawa T, Suzuki Y, Sato M, Fujimura M, Eizuka T, Watanabe H, Kitahara T, Ohta K, Shibata T, Kudo T, Inoue H, Yamaguchi I, and Kimura M.

    FEMS Microbiol. Lett.   Vol. 251   page: 193-201   2005

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  91. Circadian rhythm of circumnutation in inflorescence stems of Arabidopsis. Reviewed

    Niinuma K, Someya N, Kimura M, Yamaguchi I, and Hamamoto H.

    Plant Cell Physiol.   Vol. 46   page: 1423-1427   2005

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  92. Efficient decontamination of zearalenone, the mycotoxin of cereal pathogen, by transgenic yeasts through the expression of a synthetic lactonohydrolase gene.

    Takahashi-Ando N, Tokai T, Hamamoto H, Yamaguchi I, and Kimura M.

    Appl. Microbiol. Biotechnol.   Vol. 67   page: 838-844   2005

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  93. Characterization of genes encoding metal tolerance proteins isolated from Nicotiana glauca and Nicotiana tabacum. Reviewed

    Shingu Y, Kudo T, Ohsato S, Kimura M, Ono Y, Yamaguchi I, and Hamamoto H.

    Biochem. Biophys. Res. Commun.   Vol. 331   page: 675-680   2005

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  94. A catalytic subunit of cyclic AMP-dependent protein kinase, PKAC-1, regulates asexual differentiation in Neurospora crassa. Reviewed

    Banno S, Ochiai N, Noguchi R, Kimura M, Yamaguchi I, Kanzaki S, Murayama T, and Fujimura M.

    Genes Genet. Syst.   Vol. 80   page: 25-34   2005

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  95. Metabolism of zearalenone by genetically modified organisms expressing the detoxification gene from Clonostachys rosea.

    Takahashi-Ando N, Ohsato S, Shibata T, Hamamoto H, Yamaguchi I, and Kimura M.

    Appl. Environ. Microbiol.   Vol. 70   page: 3239-3245   2004

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  96. New TAXI-type xylanase inhibitor genes are inducible by pathogens and wounding in hexaploid wheat. Reviewed

    Igawa T, Ochiai-Fukuda T, Takahashi-Ando N, Ohsato S, Shibata T, Yamaguchi I, and Kimura M.

    Plant Cell Physiol.   Vol. 45   page: 1347-1360   2004

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  97. Pattern of N gene-mediated systemic hypersensitive response and turnover of viral replicase protein in tobbaco.

    Someya N, Niinuma K, Kimura M, Yamaguchi I, and Hamamoto H.

    Arch. Virol.   Vol. 149   page: 2105-2113   2004

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  98. Proteome analysis of wheat lemma.

    Woo SH, Kimura M, Higa-Nishiyama A, Dohmae N, Hamamoto H, Jong SK, and Yamaguchi I.

    Biosci. Biotechnol. Biochem.   Vol. 67 ( 11 ) page: 2486-2491   2003.11

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  99. Expression in cereal plants of genes that inactivate Fusarium mycotoxins.

    Higa A, Kimura M, Mimori K, Ochiai-Fukuda T, Tokai T, Takahashi-Ando N, Nishiuchi T, Igawa T, Fujimura M, Hamamoto H, Usami R, and Yamaguchi I.

    Biosci. Biotechnol. Biochem.   Vol. 67 ( 4 ) page: 914-918   2003.4

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  100. Trichothecene non-producer Gibberella species have both functional and non-functional 3-O-acetyltransferase genes.

    Kimura M, Tokai T, Matsumoto G, Fujimura M, Hamamoto H, Yoneyama K, Shibata T, and Yamaguchi I.

      Vol. 163   page: 677-684   2003

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  101. Isolation and characterization of genes specifically expressed during infection stages in the rice blast fungus.

    Banno S, Kimura M, Tokai T, Kasahara S, Higa-Nishiyama A, Takahashi-Ando N, Hamamoto H, Fujimura M, Staskawicz BJ, and Yamaguchi I.

    FEMS Microbiol. Lett.   Vol. 222   page: 223-229   2003

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  102. The trichothecene biosynthesis gene cluster of Fusarium graminearum F15 contains a limited number of essential pathway genes and expressed nonessential genes.

    Kimura M, Tokai T, O'Donnell K, Ward TJ, Fujimura M, Hamamoto H, Shibata T, and Yamaguchi I.

    FEBS Lett.   Vol. 539   page: 105-110   2003

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  103. Biotransformation of the mycotoxin, zearalenone, to a non-estrogenic compound by a fungal strain of Clonostachys sp.

    Kakeya H, Takahashi-Ando N, Kimura M, Onose R, Yamaguchi I, and Osada H.

      Vol. 66 ( 12 ) page: 2723-2726   2002.12

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  104. The flexible C-terminal region of Aspergillus terreus blasticidin S deaminase: identification of its functional roles with deletion enzymes.

    Kimura M, Furuichi M, Yamamoto M, Kumasaka T, Mizuno H, Miyano M, and Yamaguchi I.

    Biochem. Biophys. Res. Commun.   Vol. 290   page: 421-426   2002

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  105. A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

    Takahashi-Ando N, Kimura M, Kakeya H, Osada H, and Yamaguchi I.

    Biochem. J.   Vol. 365   page: 1-6   2002

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  106. Microbial toxins in plant-microbe interactions: biosynthesis, resistance mechanisms, and significance.

    Kimura M, Anzai H, and Yamaguchi I.

    J. Gen. Appl. Microbiol.   Vol. 47   page: 149-160   2001

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  107. A trichothecene efflux pump encoded by Tri102 in the biosynthetic gene cluster of Fusarium graminearum.

    Wuchiyama J, Kimura M, and Yamaguchi.

    J. Antibiot.   Vol. 53   page: 196-200   2000

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  108. Expression, purification, and characterization of blasticidin S deaminase (BSD) from Aspergillus terreus: the role of catalytic zinc in enzyme structure.

    Kimura M, Sekido S, Isogai Y, and Yamaguchi I.

    J. Biochem.   Vol. 127   page: 955-963   2000

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  109. The trichothecene biosynthesis regulatory gene from the type B producer Fusarium strains: sequence of Tri6 and its expression in Escherichia coli.

    Matsumoto G, Wuchiyama J, Shingu Y, Kimura M, Yoneyama K, and Yamaguchi I.

    Biosci. Biotechnol. Biochem.   Vol. 63 ( 11 ) page: 2001-2004   1999.11

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  110. Crystallization and preliminary X-ray diffraction studies of blasticidin S deaminase from Aspergillus terreus.

    Nakasako M, Kimura M, and Yamaguchi I.

    Acta Crystallogr. D Biol. Crystallogr.   Vol. 55   page: 547-548   1999

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  111. Features of Tri101, the trichothecene 3-O-acetyltransferase gene, related to the self-defense mechanism in Fusarium graminearum.

    Kimura M, Shingu Y, Yoneyama K, and Yamaguchi I.

    Biosci. Biotechnol. Biochem   Vol. 62 ( 5 ) page: 1033-1036   1998.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  112. Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101.

    Kimura M, Kaneko I, Komiyama M, Takatsuki A, Koshino H, Yoneyama K, and Yamaguchi I.

    J. Biol. Chem.   Vol. 273   page: 1654-1661   1998

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  113. The mystery of the trichothecene 3-O-acetyltransferase gene. Analysis of the region around Tri101 and characterization of its homologue from Fusarium sporotrichioides.

    Kimura M, Matsumoto G, Shingu Y, Yoneyama K, and Yamaguchi I.

    FEBS Lett.   Vol. 435   page: 163-168   1998

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  114. Convergent transcription units and their promoters at both ends of Pot2, an inverted repeat transposon from the rice blast fungus.

    Kimura M and Yamaguchi I.

    J. Biochem.   Vol. 124   page: 268-273   1998

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  115. Immunological detection of endopolygalacturonase secretion by Fusarium oxysporum in plant tissue and sequencing of its encoding gene.

    Arie T, Gouthu S, Shimazaki S, Kamakura T, Kimura M, Inoue M, Takio K, Ozaki A, Yoneyama K, and Yamaguchi I.

    Ann. Phytopathol. Soc. Jpn.   Vol. 64   page: 7-15   1998

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    Language:English   Publishing type:Research paper (scientific journal)  

  116. Recent development in the use of blasticidin S, a microbial fungicide, as a useful reagent in molecular biology.

    Kimura M and Yamaguchi I.

    Pestic. Biochem. Physiol.   Vol. 56   page: 243-248   1996

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  117. Blasticidin S deaminase gene (BSD): a new selection marker gene for transformation of Arabidopsis thaliana and Nicotiana tabacum.

    Tamura K, Kimura M, and Yamaguchi I.

    Biosci. Biotechnol. Biochem.   Vol. 59 ( 12 ) page: 2336-2338   1995.12

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  118. A novel transformation system for Pyricularia oryzae: adhesion of regenerating fungal protoplasts to collagen-coated dishes.

    Biosci. Biotechnol. Biochem.   Vol. 59 ( 6 ) page: 1177-1180   1995.6

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  119. GTPase activity in rice plasma membrane preparation enhanced by a priming effector for plant defense reactions.

    Sekizawa Y, Aoyama H, Kimura M, and Yamaguchi I.

    J. Pestic. Sci.   Vol. 20   page: 165-168   1995

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  120. Cloning of the blasticidin S deaminase gene (BSD) from Aspergillus terreus and its use as a selectable marker for Schizosaccharomyces pombe and Pyricularia oryzae.

    Kimura M, Kamakura T, Tao QZ, Kaneko I, and Yamaguchi I

    Mol. Gen. Genet.   Vol. 242   page: 121-129   1994

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  121. Blasticidin S deaminase gene from Aspergillus terreus (BSD): a new drug resistance gene for transfection of mammalian cells.

    Biochim. Biophys. Acta   Vol. 1219   page: 653-659   1994

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Books 25

  1. 安全で効果的な赤かび病防除剤の開発に向けて

    西内 巧、木村 真( Role: Joint author)

    日本マイコトキシン学会  2021.7 

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    Total pages:7   Responsible for pages:13-19  

    DOI: 10.2520/myco.71-1-1

  2. トリコテセン耐性に関わる側鎖修飾と異種異属のトリコテセン生産菌を利用したトリコテセンライブラリーの構築

    安藤 直子、松井 宏介、鈴木 将、貞松 和樹、小豆畑 隼、岡田 彩希、松尾 元暉、武田 博音、小泉 慶明、木村 真( Role: Joint author)

    日本マイコトキシン学会  2020.8 

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    Total pages:8   Responsible for pages:67-74   Language:Japanese

    DOI: 10.2520/myco.70-2-3

  3. トリコテセン系マイコトキシンの汚染防除にむけた研究の動向

    木村 真( Role: Sole author)

    北隆社  2018.12 

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    Total pages:5   Language:Japanese Book type:Scholarly book

  4. ムギ類赤かび病菌が産生するトリコテセン系かび毒の植物における作用機構と低減化へのアプローチ

    西内 巧、木村 真、佐藤 和広( Role: Joint author)

    日本マイコトキシン学会  2015.7 

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    Total pages:5   Responsible for pages:143-147   Language:Japanese

    DOI: 10.2520/myco.65.143

  5. トリコテセン系毒素産生制御機構の解明と汚染低減化に向けた基盤研究

    前田 一行、中嶋 佑一、市川 雛代、鬼頭 良幸、古﨑 貴大、斎藤 臣雄、本山 高幸、長田 裕之、小林 哲夫、木村 真( Role: Joint author)

    日本マイコトキシン学会  2014.1 

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    Total pages:6   Responsible for pages:69-74   Language:Japanese

    DOI: 10.2520/myco.64.69

  6. 薬剤ストレス処理により誘導される糸状菌の体細胞相同組換えを利用したマイコトキシンバイオアッセイ系への展開

    荒添 貴之、大里 修一、木村 真、有江 力、桑田 茂( Role: Joint author)

    日本マイコトキシン学会  2014.1 

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    Total pages:8   Responsible for pages:87-94   Language:Japanese

    DOI: 10.2520/myco.64.87

  7. チミジンキナーゼ遺伝子を利用したフザリウム属菌のゲノム加工技術とマイコトキシン産生制御機構研究への応用

    中嶋 佑一、市川 雛代、前田 一行、西内 巧、小林 哲夫、木村 真( Role: Joint author)

    日本マイコトキシン学会  2013 

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    Total pages:8   Responsible for pages:85-92   Language:Japanese

    DOI: 10.2520/myco.63.85

  8. Nivalenol (Fungal Sesquiterpenes). Natural Products: Phytochemistry, Botany and Metabolism of Alkaloids, Phenolics and Terpenes

    Sugita-Konishi Y and Kimura M.( Role: Joint author)

    Springer Verlag, Berlin-Heiderberg  2013 

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    Language:English

  9. Toxins of microorganisms. Comprehensive Natural Product Chemistry II Vol. 4 Chemical Ecology (Mori, K. ed.), ISBN: 978-0-08-045381-1

    Sakuda S and Kimura M.( Role: Sole author)

    Elsevier Science B.V., Amsterdam  2010 

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    Language:Japanese

  10. 病原糸状菌の浸透圧応答シグナル伝達経路

    田中 千尋、泉津 弘佑、吉見 啓、清水 公徳、木村 真、本山 高幸( Role: Joint author)

    日本農芸化学会  2009 

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    Language:Japanese

  11. カビ毒を自ら解毒する遺伝子組換え作物

    安藤 直子、井川 智子、木村 真( Role: Joint author)

    シーエムシー出版  2007 

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    Language:Japanese

  12. Biotechnology for Fusarium resistance and mycotoxin decontamination in cereal grains. Proceedings of the International Symposium on Mycotoxicology in Bangkok 2006 (Kumagai, S., ed.), ISSN 0285-1466

    Kimura M, Tokai T, and Takahashi-Ando N. ( Role: Joint author)

    Japanese Society of Mycotoxicology  2007 

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    Language:Japanese

  13. 殺菌剤ブラストサイジンSを選抜薬剤として用いるイネの効率的形質転換

    福田 徹子、安藤 直子、大里 修一、濱本 宏、木村 真、山口 勇( Role: Joint author)

    日本農薬学会  2006 

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    Language:Japanese

  14. Control of Fusarium head blight and mycotoxin contamination in grains - Towards transgenic strategies for disease management. Modern Fungicides and Antifungal Compounds IV (Dehne, H. W., Gisi, U., Kuck K. H., Russel, P. E., and Lyr H., eds.), ISBN: 1-901396-39-8

    Yamaguchi I, Igawa T, Ochiai-Fukuda T, Takahashi-Ando N, and Kimura M.( Role: Joint author)

    The British Crop Protection Council, Hampshire  2005 

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    Language:English

  15. 埼玉県で見つかったイワゼニゴケ

    井藤賀 操、木村 真、山口 勇、古木 達郎( Role: Joint author)

    日本蘚苔類学会  2004 

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    Language:Japanese

  16. バイオテクノロジーとムギ類赤かび病の制御  植物防疫

    木村 真、安藤 直子、井川 智子、東海 武史、山口 勇( Role: Sole author)

    日本植物防疫協会  2004 

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    Language:Japanese

  17. Biotechnology for Fusarium resistance and mycotoxin decontamination in cereal grains. Collaborative Research for Fusarium Head Blight Resistance in Wheat and Barley (Ban, T. ed.), ISSN 1341-710X

    Kimura M, Tokai T, Kadokura K, Igawa T, Ochiai-Fukuda T, Ohsato S, Higa-Nishiyama A, Takahashi-Ando N, and Yamaguchi I. ( Role: Joint author)

    JIRCAS, Tsukuba  2004 

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    Language:English

  18. Fusarium mycotoxins: biosynthesis and biodegradation. New Horizon of Mycotoxicology for Assuring Food Safety. Proceedings of the International Symposium of Mycotoxicology in Kagawa 2003 (Yoshizawa, T., ed.), ISBN 4-938236-86-9 C3045

    Kimura M, Tokai T, Takahashi-Ando N, and Yamaguchi I. ( Role: Joint author)

    Bikohsha, Takamatsu  2004 

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    Language:English

  19. 植物機能統御機構解明の新展開—植物バイオテクノロジーと環境

    山口 勇、濱本 宏、木村 真、本山 高幸( Role: Joint author)

    日本農芸化学会  2002 

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    Language:Japanese

  20. Molecular biology and genetics of trichothecene mycotoxin producers: progress and perspective. Production of Secondary Metabolites by Microorganisms: Biosynthesis, Genetics, and Regulation (Fierro, F. and Martin, J. F., eds.), ISBN: 81-7736-113-9

    Kimura M, Fujimura M, Hamamoto H, Tokai T, and Yamaguchi I.( Role: Sole author)

    Research Signpost, Trivandrum  2002 

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    Language:Japanese

  21. An unexpected gift from fungicide metabolism studies: blasticidin S deaminase (BSD) from Aspergillus terreus. Progress in Biotechnology vol. 22. Molecular Anatomy of Cellular Systems (Endo, I., Kudo, T., Osada, H., Shibata, T., and Yamaguchi, I. eds.), ISBN: 0-444-50739-6

    Kimura M, Yamamoto M, Furuichi M, Kumasaka T, and Yamaguchi I.( Role: Joint author)

    Elsevier Science B.V., Amsterdam  2002 

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    Language:English

  22. The mystery of the trichothecene 3-O-acetyltransferase gene: Tri101 evolved independent of other trichothecene biosynthetic genes in the gene cluster. - Extended Summary (9th International Congress of Pesticide Chemistry).

    Kimura M and Yamaguchi I.( Role: Joint author)

    Pestic. Sci.   1999 

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    Language:English

  23. 農業用抗生物質ブラストサイジンS—不活化酵素の発見とその遺伝子の利用  バイオサイエンスとバイオインダストリー 

    木村 真、山口 勇( Role: Joint author)

    バイオインダストリー協会  1998 

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    Language:Japanese

  24. ブラストサイジンS利用の新展開—農業用抗生物質から分子生物学研究用選択薬剤へ 化学と生物

    木村 真、山口 勇( Role: Joint author)

    日本農芸化学会  1996 

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    Language:Japanese

  25. 安全で効果的な赤かび病防除剤の開発に向けて

    西内 巧、木村 真( Role: Joint author)

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Research Project for Joint Research, Competitive Funding, etc. 18

  1. 安定・安全な食糧供給の実現を目指した革新的なバイオコントロール技術の開発

    2021.12 - 2023.3

    国立大学イノベーション創出環境強化事業交付金(重点支援③) 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3200000

  2. コーヒー抽出後の残渣SCGを利用した食品カビの効率的増殖を目指した萌芽研究

    2021.9 - 2022.8

    2021年度「キーコーヒー柴田裕記念財団」研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000

  3. トリコテセン系かび毒生合成制御の分子機構

    Grant number:G-2021-2-098  2021.4 - 2023.3

    公益財団法人発酵研究所  公益財団法人発酵研究所 2021年度一般研究助成 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3000000 ( Direct Cost: \3000000 )

  4. 天然物を活用した作物病害防除とかび毒汚染制御

    Grant number:28007AB  2019.4 - 2022.3

    農業・食品産業技術総合研究機構:イノベーション創出強化研究推進事業 

    木村真

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    Grant type:Competitive

    Grant amount:\104338400

  5. アミノ酸代謝シグナルを利用したマイコトキシン産生抑制機構の解明

    Grant number:2017S056  2017.6 - 2018.3

    2017年度 旗影会研究助成 

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    Grant type:Competitive

    Grant amount:\1000000

  6. 天然素材を活用した穀類のかび毒汚染低減化技術の創成

    Grant number:28007  2016.7 - 2019.3

    農林水産業・食品産業科学技術研究推進事業 シーズ創出ステージ 

    木村真

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    Grant type:Competitive

    Grant amount:\27500000

  7. トリコテセン系かび生合成進化の解明と標準化合物ライブラリーの構築

    Grant number:H27 Joint Research No.11  2016.5 - 2017.4

    平成27年度 飯島記念食品科学振興財団学術研究助成金 

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    Grant type:Competitive

    Grant amount:\3500000

  8. セスキテルペン代謝工学に向けた基盤研究

    2015.4 - 2016.3

    野田産研研究助成 

    木村真

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    Grant type:Competitive

    Grant amount:\2000000

  9. オカラ細胞壁の可溶化と機能性成分の探索にむかう食用カビの基盤研究

    2015 - 2016

    平成27年度 研究助成金 

    木村真

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    Grant type:Competitive

  10. トリコテセン系かび毒産生制御技術の開発にむけた基盤研究

    2013.6 - 2014.4

    平成25年度 学術奨励金 

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    Grant type:Competitive

  11. 「ケミカルバイオロジーを基盤とした革新的な農薬等の探索研究」のうち分担課題「ムギ類赤かび病菌制御化合物の探索」

    2011.8 - 2016.3

    イノベーション創出基礎的研究推進事業 

    長田裕之

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    Grant type:Competitive

  12. ニバレノール型カビ毒の迅速で正確な酵素免疫学的測定のための前処理法の開発

    2011.5 - 2012.4

    平成22年度 飯島記念食品科学振興財団学術研究助成金 

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    Grant type:Competitive

  13. 穀類の安全を脅かすニバレノール型カビ毒の後期生合成の解明

    2010.5 - 2011.4

    平成21年度 飯島記念食品科学振興財団学術研究助成金 

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    Grant type:Competitive

  14. 未来世代のための革新的もの作り‐植物病原菌を利用した医薬原料の圃場的大量生産にむけて

    2006.4 - 2007.3

    平成18年度 化学素材研究開発振興財団記念基金「グラント」研究奨励金 

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    Grant type:Competitive

  15. 天然環境毒素による重要穀類の汚染低減化にむけた技術創成

    2005.8 - 2008.3

    新技術・新分野創出のための基礎研究推進事業 

    木村真

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    Grant type:Competitive

  16. 国産技術を応用した病害抵抗性・微生物毒素非蓄積性組換え穀類の開発

    2004.10 - 2005.9

    産業界連携制度 

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    Grant type:Competitive

  17. 平成15〜17年度農林水産省受託研究「食品の安全性及び機能性に関する総合研究」のうち分担課題「 赤かび病菌マイコトキシン不活化・解毒遺伝子の穀類における発現と産生抑制技術の開発」

    2003.4 - 2005.3

  18. トリコテセン生合成遺伝子の探索と解析

    1997.6 - 1998.3

    平成9年度 研究奨励費 

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 7

  1. フザリウムのユニークな二次代謝生合成制御機構の解明

    2022.4

    科学研究費補助金  基盤研究(C)

    木村 真

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    Authorship:Principal investigator  Grant type:Competitive

  2. 新規糖抱合masked mycotoxinーその生産機構と食へのリスク検証(分担)

    2021.4

    科学研究費補助金  基盤研究(C)

    安藤 直子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  3. 新規かび毒の探索・創出と先進的な食の安全検査体制の整備に向けた基盤研究(分担)

    2018.4 - 2021.3

    科学研究費補助金  基盤研究(C)

    安藤 直子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  4. ニバレノール系カビ毒の側鎖統一に向けた技術創成とその検出への応用利用(分担)

    2015.4 - 2018.3

    科学研究費補助金  基盤研究(C)

    安藤 直子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  5. フザリウム属菌を宿主としたセスキテルペンの代謝工学

    2011.4 - 2014.3

    科学研究費補助金  挑戦的萌芽研究

    木村 真

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    Authorship:Principal investigator 

  6. 生物間相互作用に関わるセスキテルペンの構造多様性を生み出す遺伝的メカニズムの解明

    2008.4 - 2011.3

    科学研究費補助金  基盤研究(C)

    木村 真

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    Authorship:Principal investigator  Grant type:Competitive

  7. 様々なトリコテセン毒素を生産するフザリウム属菌の毒素生合成遺伝子の単離と解析

    2005.4 - 2007.3

    科学研究費補助金  基盤研究(C)

    木村 真

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    Authorship:Principal investigator  Grant type:Competitive

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Industrial property rights 1

  1. ブラストサイジンSデアミナーゼ遺伝子

    山口 勇、木村 真、鎌倉 高志

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    Application no:特開平06-070768  Date applied:1994.3

    Country of applicant:Domestic  

    微生物源農薬であるブラストサイジンSの不活性化酵素遺伝子(BSD)を選択マーカー遺伝子とした動物細胞、植物、微生物等の形質転換系

 

Teaching Experience (On-campus) 85

  1. Applied Microbiology

    2023

  2. Microbiology 2

    2023

  3. Microbiology

    2023

  4. Microbiology 1

    2023

  5. Microbiology 1

    2023

  6. Applied Microbiology

    2022

  7. Microbiology 2

    2022

  8. Microbiology

    2022

  9. Bioagricultural Science Laboratory

    2022

  10. Research Methods in Applied Biosciences 1

    2022

  11. Research Methods in Applied Biosciences 2

    2022

  12. Microbiology 1

    2022

  13. 農学セミナー1

    2022

  14. Guide to Information Literacy

    2021

  15. Microbiology (G30 program 3rd year Spring semester)

    2021

  16. Microbiology 2

    2021

  17. Microbiology

    2021

  18. Applied Microbiology

    2021

  19. Microbiology 1

    2021

  20. 生命農学演習4

    2021

  21. 生命農学演習3

    2021

  22. 生命農学演習2

    2021

  23. 生命農学演習1

    2021

  24. 修士論文研究4

    2021

  25. 修士論文研究3

    2021

  26. 修士論文研究2

    2021

  27. 修士論文研究1

    2021

  28. Microbiology (G30 program 3rd year Spring semester)

    2020

  29. Microbiology 2

    2020

  30. Microbiology 1

    2020

  31. Guide to Information Literacy

    2020

  32. 修士論文研究4

    2020

  33. 修士論文研究3

    2020

  34. 修士論文研究2

    2020

  35. 修士論文研究1

    2020

  36. 生命農学演習4

    2020

  37. 生命農学演習3

    2020

  38. 生命農学演習2

    2020

  39. 生命農学演習1

    2020

  40. 応用生命科学科実験実習(分子生物学実験) (2019年度)

    2019

  41. 微生物学1 (学部2年)

    2019

  42. 分子細胞機構学特論IV

    2019

  43. 分子細胞機構学演習IV

    2019

  44. Microbiology (G30 program 3rd year Spring semester)

    2019

  45. Microbiology (G30 program 3rd year Spring semester)

    2018

  46. 微生物学2(学部3年)

    2018

  47. 微生物学1 (学部2年)

    2018

  48. 分子細胞機構学特論IV

    2018

  49. 分子細胞機構学演習IV

    2018

  50. 応用生命科学科実験実習(分子生物学実験) (2018年度)

    2018

  51. 分子細胞機構学演習IV

    2017

  52. 分子細胞機構学特論IV

    2017

  53. Microbiology (G30 program 3rd year Spring semester)

    2017

  54. 微生物学2(学部3年)

    2017

  55. 微生物学1 (学部2年)

    2017

  56. 応用生命科学科実験実習(分子生物学実験) (2017年度)

    2017

  57. 応用生命科学科実験実習(分子生物学実験)

    2016

  58. Microbiology (G30 program 3rd year Spring semester)

    2016

  59. 分子細胞機構学演習IV

    2016

  60. 分子細胞機構学特論IV

    2016

  61. 微生物学1 (学部2年)

    2016

  62. 応用生命科学科実験実習(分子生物学実験)

    2015

  63. 分子細胞機構学演習IV

    2015

  64. 分子細胞機構学特論IV

    2015

  65. Microbiology (G30 program 3rd year Spring semester)

    2015

  66. 微生物学1 (学部2年)

    2015

  67. 分子細胞機構学演習IV

    2014

  68. 分子細胞機構学特論IV

    2014

  69. 応用生命科学科実験実習(実験基礎)

    2014

  70. Microbiology (G30 program 3rd year Spring semester)

    2014

  71. Microbiology 1

    2014

  72. 応用生命科学科実験実習(分子生物学実験)

    2014

  73. バイオテクノロジー(理系教養科目)

    2014

  74. 応用生命科学科実験実習(分子生物学実験)

    2013

  75. 応用生命科学科実験実習(実験基礎)

    2013

  76. 分子細胞機構学特論IV

    2013

  77. 分子細胞機構学演習IV

    2013

  78. Biotechinology

    2013

  79. Microbiology 1

    2013

  80. Microbiology 1

    2012

  81. 応用生命科学科実験実習(分子生物学実験)

    2012

  82. 分子細胞機構学特論IV

    2012

  83. 分子細胞機構学演習IV

    2012

  84. Biotechinology

    2012

  85. 応用生命科学科実験実習(分子生物学実験)

    2011

▼display all

 

Social Contribution 1

  1. 名大 MIRAI GSC(次世代人材育成時事業グローバルサイエンスキャンプ)

    Role(s):Demonstrator

    2018.7 - 2018.8

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    Audience: High school students

    Type:Seminar, workshop

Academic Activities 5

  1. Bioscience, Biotechnology, and Biochemistry: Editor International contribution

    Role(s):Review, evaluation, Peer review

    2023.3

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    Type:Scientific advice/Review 

  2. Frontiers in Microbiology: Associate Editor International contribution

    Role(s):Review, evaluation, Peer review

    2022.5

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    Type:Scientific advice/Review 

  3. International Journal of Molecular Sciences: Editorial Board Member International contribution

    Role(s):Review, evaluation, Peer review

    2019.10

     More details

    Type:Scientific advice/Review 

  4. JSM Mycotoxins: Advisory Board Member International contribution

    Role(s):Supervision (editorial), Review, evaluation, Peer review

    2017.1

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    Type:Scientific advice/Review 

  5. JSM Mycotoxins: Editor-in-Chief International contribution

    Role(s):Review, evaluation, Peer review

    2010.1 - 2016.12

     More details

    Type:Scientific advice/Review