研究者詳細 - 六鹿　雅登

論文 - 六鹿　雅登

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The Incidence and Influencing Factors of In-hospital Frailty Progression following Transcatheter Aortic Valve Implantation. Open Access

Miyazaki T, Tanaka A, Tokuda Y, Shirai Y, Mizutani K, Furusawa K, Akita S, Ozeki T, Kobayashi K, Ishii H, Mutsuga M, Murohara T

Internal medicine (Tokyo, Japan) 63 巻 ( 24 ) 頁： 3283 - 3289 2024年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本内科学会

Objective Patients undergoing transcatheter aortic valve implantation (TAVI) are generally older and frailty is therefore an important clinical issue. The baseline degree of frailty is associated with the prognosis in patients undergoing TAVI; however, the incidence of in-hospital frailty progression and its influencing factors have not yet been elucidated. Methods This observational, single-center study retrospectively evaluated 281 patients who underwent TAVI. The degree of frailty at baseline and discharge was evaluated using the Clinical Frailty Scale (CFS). In-hospital frailty progression was defined as an increase of at least one level in the CFS score at discharge from baseline, and predictors of frailty progression were assessed. Results The median baseline CFS score was 4.0 (interquartile range: 3.0-4.0). In-hospital frailty progression was observed in 49 patients (17.4%). No significant differences were observed in age, sex, comorbidities, or surgical risk scores between patients with and without frailty progression. Patients with frailty progression experienced stroke more frequently during hospitalization than those without (12.2% vs. 1.3%, p=0.001). A multivariable logistic analysis showed that in-hospital stroke was a significant predictor of frailty progression (odds ratio, 10.7; 95% confidence interval: 2.34-49.2, p=0.002). Patients with frailty progression had a longer hospital stay than those without frailty progression [7.0 (4.0-17.0) vs. 4.0 (4.0-8.0) days, p=0.001]. Conclusion In-hospital frailty progression was not uncommon in patients undergoing TAVI. Stroke incidence was a significant influencing factor in frailty progression, whereas baseline comorbidities and surgical risks were not.

DOI： 10.2169/internalmedicine.3146-23

Clinical Features and Postoperative Mobilization following Total Aortic Arch Replacement

Shirai, Y; Tokuda, Y; Tsuchikawa, Y; Kobayashi, K; Tanaka, S; Yoshito, N; Hori, Y; Takagi, D; Nishida, Y; Mutsuga, M

INTERNATIONAL HEART JOURNAL 65 巻 ( 6 ) 頁： 1075 - 1078 2024年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人インターナショナル・ハート・ジャーナル刊行会

Open thoracic aortic surgery is believed to necessitate more intensive rehabilitation. This study aimed to compare the progress of postoperative rehabilitation between standard and delayed mobilization. A retrospective review was conducted on 199 patients who underwent isolated total aortic arch replacement via median ster-notomy. Cases of in-hospital mortality and postoperative stroke were excluded. Based on the current guidelines for cardiovascular rehabilitation of the Japanese Circulation Society, patients were categorized into standard mobilization (could sit on the edge of bed within 2 days) and delayed mobilization (could not do so) groups. Rehabilitation progress was compared among both groups. Initial mobilization was delayed in 100 patients (de-layed mobilization group), primarily because of respiratory failure (46.0%). Preoperative risk characteristics, in-cluding EuroSCORE II (median, 2.9 versus 3.5), were similar between the standard and delayed mobilization groups. The delayed mobilization group had longer operation (median, 6.1 versus 8.0 hours, P < 0.001) and cardiopulmonary bypass (median, 3.2 versus 4.1 hours, P < 0.001) times. Independent ambulation occurred earlier in the standard mobilization group (median, 6.0 versus 8.0 days, P < 0.001). In conclusion, early initiation of sitting on the edge of the bed within 2 days was associated with earlier independent ambulation during postoperative rehabilitation, which supports the current guidelines. Longer operation and cardiopulmonary bypass times were associated with delayed mobilization initiation, suggesting the need for more tailored approaches in such cases.

DOI： 10.1536/ihj.24-261

DT LVADの現状と今後-DT治療の拡大による諸問題への取り組み(患者の看取りを含めて) DT-LVAD実施施設新規参入後1年間に施行した4例の検討

吉住朋, 植村友稔, 山本暁邦, 平岩宏章, 風間信吾, 近藤徹, 森本竜太, 奥村貴裕, 六鹿雅登

人工臓器 53 巻 ( 2 ) 頁： S - 56 2024年10月

最新のLVAD治療における合併症抑止への取り組みドライブライン感染撲滅を目指した当院の取り組み

吉住朋, 林泰成, 風間信吾, 平岩宏章, 近藤徹, 森本竜太, 奥村貴裕, 六鹿雅登

人工臓器 53 巻 ( 2 ) 頁： S - 71 2024年10月

現代の日本に適した臓器アロケーションシステムの確立に向けて心臓移植におけるアロケーションシステムの課題と改善への提案

奥村貴裕, 風間信吾, 平岩宏章, 近藤徹, 森本竜太, 吉住朋, 六鹿雅登, 室原豊明

移植 59 巻 ( 総会臨時 ) 頁： 191 - 191 2024年9月

拡張相肥大型心筋症に対して心臓移植4年経過後、肺高血圧症の合併を診断された一例

平岩宏章, 長井伸, 伊藤亮太, 小山雄一郎, 近藤喜代太, 風間信吾, 近藤徹, 森本竜太, 奥村貴裕, 伊藤英樹, 吉住朋, 六鹿雅登, 室原豊明

移植 58 巻 ( 4 ) 頁： 407 - 408 2024年3月

Factors associated with postsurgical muscle weakness in patients who undergo thoracic aortic surgery: a retrospective cohort study 国際誌

Shimizu, M; Adachi, T; Kobayashi, K; Mutsuga, M; Oshima, H; Usui, A; Yamada, S

PHYSIOTHERAPY THEORY AND PRACTICE 39 巻 ( 10 ) 頁： 2180 - 2188 2023年10月

当院のMCS使用下で発症した頭蓋内出血症例の検討

長井伸, 森本竜太, 伊藤亮太, 近藤喜代太, 小山雄一郎, 風間信吾, 平岩宏章, 奥村貴裕, 六鹿雅登, 室原豊明

人工臓器 52 巻 ( 2 ) 頁： S - 103 2023年10月

心臓移植Allocation Systemは具体的にどのように変更すべきか心臓移植待機中の現状とHeart Allocation System改定への課題

奥村貴裕, 六鹿雅登, 風間信吾, 平岩宏章, 森本竜太, 吉住朋, 室原豊明

移植 58 巻 ( 総会臨時 ) 頁： 154 - 154 2023年9月

Cardiac rehabilitation in a heart failure patient using customized “cardiac support net” treatment: A case report 査読有り

Kiyonori Kobayashi, Toshiaki Akita, Sho Akita, Hideki Ito, Sachie Terazawa, Masato Mutsuga, Akihiko Usui

Nagoya J Med Sci 85 巻 ( 3 ) 頁： 626 - 634 2023年8月

Cardiac Rehabilitation in Severe Heart Failure Patients with Impella 5.0 Support via the Subclavian Artery Approach Prior to Left Ventricular Assist Device Implantation

Shimizu, M; Hiraiwa, H; Tanaka, S; Tsuchikawa, Y; Ito, R; Kazama, S; Kimura, Y; Araki, T; Mizutani, T; Oishi, H; Kuwayama, T; Kondo, T; Morimoto, R; Okumura, T; Ito, H; Yoshizumi, T; Mutsuga, M; Usui, A; Murohara, T

JOURNAL OF PERSONALIZED MEDICINE 13 巻 ( 4 ) 頁： 630 - 630 2023年4月

移植前後における心筋生検のキーポイント

奥村貴裕, 木村祐樹, 平岩宏章, 坂本岳, 小山雄一郎, 伊藤亮太, 風間信吾, 森本竜太, 伊藤英樹, 吉住朋, 六鹿雅登, 室原豊明

移植 57 巻 ( 4 ) 頁： 391 - 391 2023年4月

植込み型左室補助人工心臓装着患者における運動能力の軌跡(Trajectory of Exercise Capacity in Patients with Durable Left Ventricular Assist Device)

風間信吾, 坂本岳, 伊藤亮太, 木村祐樹, 小山雄一郎, 平岩宏章, 近藤徹, 森本竜太, 奥村貴裕, 吉住朋, 六鹿雅登, 室原豊明

日本循環器学会学術集会抄録集 87回巻頁： OJ05 - 6 2023年3月

Impact of an improved driveline management for HeartMate II and HeartMate 3 left ventricular assist devices 国際誌

Mutsuga, M; Okumura, T; Morimoto, R; Kondo, T; Ito, H; Terazawa, S; Tokuda, Y; Narita, Y; Nishida, K; Murohara, T; Usui, A

ARTIFICIAL ORGANS 47 巻 ( 2 ) 頁： 387 - 395 2023年2月

Impact of Early Ambulation on the Prognosis of Coronary Artery Bypass Grafting Patients

Tsuchikawa, Y; Tokuda, Y; Ito, H; Shimizu, M; Tanaka, S; Nishida, K; Takagi, D; Fukuta, A; Takeda, N; Yamamoto, H; Hori, M; Nishida, Y; Mutsuga, M

CIRCULATION JOURNAL 87 巻 ( 2 ) 頁： 306 - + 2023年1月

植込型補助人工心臓治療管理施設からの提言心臓移植実施施設、DT非実施施設における重症心不全管理

奥村貴裕, 六鹿雅登, 木村祐樹, 風間信吾, 平岩宏章, 森本竜太, 伊藤英樹, 吉住朋, 室原豊明

人工臓器 51 巻 ( 2 ) 頁： S - 47 2022年10月

Relationship between muscle strength and rehospitalization in ventricular assist device patients 国際誌

Kobayashi, K; Mutsuga, M; Usui, A

SCIENTIFIC REPORTS 12 巻 ( 1 ) 頁： 50 - 50 2022年1月

胸部大動脈手術患者における術後筋力低下の関連因子

清水美帆, 足立拓史, 小林聖典, 六鹿雅登, 大島英揮, 碓氷章彦, 山田純生

日本臨床生理学会雑誌 51 巻 ( 4 ) 頁： 60 - 60 2021年10月

左室補助人工心臓患者における6分間歩行距離の遠隔期成績に関する検討

小林聖典, 六鹿雅登, 高木大地, 堀将也, 服部慶子, 伊藤英樹, 碓氷章彦

日本臨床生理学会雑誌 51 巻 ( 4 ) 頁： 60 - 60 2021年10月

Left brachiocephalic vein aneurysm: a case report

Ueno Harushi, Yazawa Mari, Tsubouchi Hideki, Nakanishi Keita, Sugiyama Tomoshi, Kadomatsu Yuka, Goto Masaki, Ozeki Naoki, Nakamura Shota, Fukui Takayuki, Mutsuga Masato, Yoshikawa Toyofumi Fengshi Chen

SURGICAL CASE REPORTS 7 巻 ( 1 ) 頁： 66 2021年3月

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