Faculty Profiles - OHTSUKI Chikara

Papers - OHTSUKI Chikara

Division display 21 - 40 of about 361 ／ All the affair displays >>

Double-hydrophobic elastin-like polypeptides with added functional motifs: Self-assembly and cytocompatibility

Duc H. T. Le, Yoko Tsutsui, Ayae Sugawara-Narutaki, Hiroshi Yukawa, Yoshinobu Baba, Chikara Ohtsuki

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Vol. 105 ( 9 ) page： 2475 - 2484 2017.9

Language：English Publishing type：Research paper (scientific journal) Publisher：WILEY

We have recently developed a novel double-hydrophobic elastin-like triblock polypeptide called GPG, designed after the uneven distribution of two different hydrophobic domains found in elastin, an extracellular matrix protein providing elasticity and resilience to tissues. Upon temperature trigger, GPG undergoes a sequential self-assembling process to form flexible beaded nanofibers with high homogeneity and excellent dispersibility in water. Given that GPG might be a potential elastin-mimetic material, we sought to explore the biological activities of this block polypeptide. Besides GPG, several functionalized derivatives were also constructed by fusing functional motifs such as KAAK or KAAKGRGDS at the C-terminal of GPG. Although the added motifs affected the kinetics of fiber formation and -sheet contents, all three GPGs assembled into beaded nanofibers at the physiological temperature. The resulting GPG nanofibers preserved their beaded structures in cell culture medium; therefore, they were coated on polystyrene substrates to study their cytocompatibility toward mouse embryonic fibroblasts, NIH-3T3. Among the three polypeptides, GPG having the cell-binding motif GRGDS derived from fibronectin showed excellent cell adhesion and cell proliferation properties compared to other conventional materials, suggesting its promising applications as extracellular matrices for mammalian cells. (C) 2017 Wiley Periodicals, Inc.

DOI： 10.1002/jbm.a.36105

Web of Science

PubMed

Bioactive Glass-Ceramics

Yokoi, T; Miyazaki, T; Kawashita, M; Ohtsuki, C

NANOBIOCERAMICS FOR HEALTHCARE APPLICATIONS page： 213 - 237 2017

Rapid and topotactic transformation from octacalcium phosphate to hydroxyapatite (HAP): a new approach to self-organization of free-standing thin-film HAP-based nanohybrids Reviewed

Satoshi Kajiyama, Takeshi Sakamoto, Moe Inoue, Tatsuya Nishimura, Taishi Yokoi, Chikara Ohtsuki and Takashi Kato

CrystEngComm Vol. 18 page： 8388-8395 2016.9

Fabrication of Porous α-TCP/Gellan Gum Scaffold for Bone Tissue Engineering Reviewed

Jian Wen, Ill Yong Kim, Koichi Kikuta and Chikara Ohtsuki

Journal of Nanoscience and Nanotechnology Vol. 16 page： 3077-3083 2016.3

Optimization of Sintering Conditions for Improvement of Mechanical Property of α-Tricalcium Phosphate Blocks

Jian Wen, Ill Yong Kim, Koichi Kikuta and Chikara Ohtsuki

Global Journal of Biotechnology and Biomaterial Science Vol. 2 page： 1-7 2016.1

Hydroxyapatite Formation from Calcium Carbonate Single Crystal under Hydrothermal Condition: Effects of Processing Temperature

Ill Yong Kim, and Chikara Ohtsuki

Ceramics International Vol. 42 page： 1886-1890 2015.11

Continuous expansion of the interplanar spacing of octacalcium phosphate by incorporation of dicarboxylate ions with a side chain Reviewed

Taishi Yokoi, Masanobu Kamitakahara and Chikara Ohtsuki

Dalton Transactions Vol. 44 page： 7943-7950 2015.5

Hydroxyapatite formation on titania-based materials in a solution mimicking body fluid: Effects of manganese and iron addition in anatase Reviewed

Euisup Shin, Ill Yong Kim, Sung Baek Cho and Chikara Ohtsuki

Materials Science and Engineering: C Vol. 48 page： 279-286 2015.3

Calcium phosphate-forming ability of magnetite and related materials in a solution mimicking in vivo conditions Reviewed

Yasuyuki Kato, Taishi Yokoi, Euisup Shin, Ill Yong Kim, Masakazu Kawashita, Koichi Kikuta and Chikara Ohtsuki

Journal of Asian Ceramic Societies Vol. 3 page： 44-49 2015.3

Hydroxyapatite formation on oxidized cellulose nanofibers in a solution mimicking body fluid Reviewed

Seira Morimune-Moriya, Sakina Kondo, Ayae Sugawara-Narutaki, Tatsuya Nishimura, Takashi Kato and Chikara Ohtsuki

Polymer Journal 2015.2

A unified in vitro evaluation for apatite-forming ability of bioactive glasses and their variants Reviewed

Anthony L. B. Maçon, Taek B. Kim, Esther M. Valliant, Kathryn Goetschius, Richard K. Brow, Delbert E. Day, Alexander Hoppe, Aldo R. Boccaccini, Ill Yong Kim, Chikara Ohtsuki, Tadashi Kokubo, Akiyoshi Osaka, Maria Vallet-Regí, Daniel Arcos, Leandro Fraile, Antonio J. Salinas, Alexandra V. Teixeira, Yuliya Vueva, Rui M. Almeida, Marta Miola, Chiara Vitale-Brovarone, Enrica Verné, Wolfram Höland, and Julian R. Jones

Journal of Materials Science: Materials in Medicine Vol. 26 page： Article 115 (10 pages) 2015.2

Fabrication of Self-Standing Films Consisting of Enamel-Like Oriented Nanorods Using Artificial Peptide Reviewed

Kazuki Aita, Yuya Oaki, Chikara Ohtsuki and Hiroaki Imai

CrystEngComm Vol. 17 page： 5551-5555 2015

Hydroxyapatite formation through dissolution-precipitation reaction: Effects of solubility of starting materials Reviewed

Ill Yong Kim, Koichi Kikuta and Chikara Ohtsuki

Ceramics International 2014.6

Utilization of star-shaped polymer architecturein the creation of high-density polymer brush coatings for the prevention of platelet and bacteria adhesion Reviewed

Masayasu Totani, Tsuyoshi Ando, Kayo Terada, Takaya Terashima, Ill Yong Kim, Chikara Ohtsuki, Chuanwu Xi, Kenichi Kuroda and Masao Tanihara

Biomaterials Science, 2014 2014.5

Characteristics of glass ionomer cements composed of glass powders in CaO-SrO-ZnO-SiO₂ system prepared by two dfferent synthetic routes Reviewed

Ill Yong Kim, Chikara Ohtsuki, Aisling Coughlan, Lana Placek, Anthony W. Wren, Mark R. Towler

Journal of Materials Science: Materials in Medicine Vol. 24 ( 12 ) page： 2677-2682 2013.12

Effects of polymer concentration on the morphology of calcum phosphate crystals formed in polyacrylamide hydrogels Reviewed

Taishi Yokoi, Masakazu Kawashita and Chikara Ohtsuki

Journal of Crystal Growth Vol. 383 page： 166-171 2013.11

Behavior of hydroxyapatite crystals in a simulated body fluid: Effects of crystal face Reviewed

Hiroyuki Shibata, Taishi Yokoi, Tomoyo Goto, Ill Yong Kim, Masakazu Kawashita, Koichi Kikuta and Chikara Ohtsuki

Journal of the Ceramic Society of Japan Vol. 121 page： 807-812 2013.9

Biomimetic mineralization of calcium phosphates in polymeric hydrogels containing carboxyl groups Reviewed

Taishi Yokoi, Masakazu Kawashita and Chikara Ohtsuki

Journal of Asian Ceramic Societies Vol. 1 page： 155-162 2013.8

Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid

Toshiki Miyazaki, Akimasa Kuramoto, Atsuhide Hirakawa, Yuki Shirosaki and Chikara Ohtsuki

Dental Materials Journal Vol. 32 ( 4 ) page： 544-549 2013.7

Formation of serrated nanorods of hydroxyapatite through organic modification under hydrothermal processing Reviewed

S. Prakash Parthiban, Ill Yong Kim, Koichi Kikuta and Chikara Ohtsuki

Journal of Nanoparticle Research Vol. 15 page： 1657-1666 2013.5

　 PREV - NEXT 　

<OHTSUKI Chikara>

Papers - OHTSUKI Chikara