Faculty Profiles - OHTSUKI Chikara

Papers - OHTSUKI Chikara

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Effect of Ions in Aqueous Media on Hydroxyapatite Induction by Silica Gel and its Relevance to Bioactivity of Bioactive Glasses and Glass-ceramics Reviewed

P. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga, T. Nakamura and T. Yamamuro

J. Applied Biomaterials Vol. 4 page： 221-229 1993

Effects of ions dissolved from bioactive glass-ceramic on surface apatite formation Reviewed

T. Kokubo, H. Kushitani, C. Ohtsuki, S. Sakka and T. Yamamuro

J. Mater. Sci.: Materials in Medicine Vol. 4 page： 1-4 1993

Processes of formation of bone-like apatite layer on silica gel Reviewed

P. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga, T. Nakamura and T. Yamamuro

J. Mater. Sci.: Materials in Medicine Vol. 4 page： 127-131 1993

Apatite formation on three kinds of bioactive material at an early stage in vivo: A comparative study by transmission electron microscopy Reviewed

M. Neo, T. Nakamura, C. Ohtsuki, T. Kokubo and T. Yamamuro

J. Biomed. Mater. Res. Vol. 27 page： 999-1006 1993

Mechanism of apatite formation on CaO-SiO₂-P₂O₅ glasses in a simulated body fluid Reviewed

Chikara Ohtsuki, Tadashi Kokubo and Takao Yamamuro

Journal of Non-Crystalline Solids Vol. 143 page： 84-92 1992.5

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

It has been shown for various types of glasses and glass-ceramics that the essential condition for them to bond to living bone is the formation of an apatite layer on their surfaces in the body. CaO,SiO2-based glasses formed the surface apatite layer in a simulated body fluid, whereas CaO,P2O5-based glasses did not form it. This means that the rate of the apatite nucleation on the surfaces of the former glasses is much higher than that of the latter glasses. The increase in the degree of the supersaturation of the surrounding fluid with respect to the apatite due to dissolution of the calcium ion from the CaO,SiO2-based glasses was almost equal to that due to dissolution of the phosphate ion from the CaO,P2O5-based glasses. The high rate of the apatite nucleation on the surface of the former glasses is therefore attributed to the lower interface energy between the apatite and the glass surfaces. The CaO,SiO2-based glasses form a silica hydrogel on their surfaces prior to formation of the apatite layer. This means that the hydrated silica provides specific favorable sites for the apatite nucleation.

DOI： 10.1016/S0022-3093(05)80556-3

Compositional dependence of bioactivity of glasses in the system CaO-SiO₂-Al₂O₃: Its in vitro evaluation Reviewed

C. Ohtsuki, T. Kokubo and T. Yamamuro

J. Mater. Sci.: Materials in Medicine Vol. 3 page： 119-125 1992.3

A comparative study of ultrastructures of the interfaces between four kinds of surface-active ceramic and bone Reviewed

M. Neo, S. Kotani, T. Nakamura, T. Yamamuro, C. Ohtsuki, T. Kokubo and Y. Bando

J. Biomed. Mater. Res. Vol. 26 page： 1419-1432 1992

Differences in ceramic-bone interface between surface-active ceramics and resorbable ceramics: A study by scanning and transmission electron microscopy Reviewed

M. Neo, S. Kotani, Y. Fujita, T. Nakamura, T. Yamamuro, Y. Bando, C. Ohtsuki and T. Kokubo

J. Biomed. Mater. Res. Vol. 26 page： 255-267 1992

Chemical reaction of bioactive glass and glass-ceramics with a simulated body fluid Reviewed

T. Kokubo, H. Kushitani, C. Ohtsuki, S. Sakka and T. Yamamuro

J. Mater. Sci.: Materials in Medicine Vol. 3 page： 79-83 1992

Apatite Formation Induced by Silica Gel in a Simulated Body Fluid Reviewed

P. Li, C. Ohtsuki, T. Kokubo, K. Nakanishi, N. Soga, T. Nakamura and T. Yamamuro

J. Am. Ceram. Soc. Vol. 75 page： 2094-2097 1992

Mechanism and strength of bonding between two bioactive ceramics in vivo Reviewed

Y. Fujita, T. Yamamuro, T. Nakamura, T. Kitsugi, S. Kotani, C. Ohtsuki and T. Kokubo

J. Biomed. Mater. Res. Vol. 26 page： 1311-1324 1992

Compositional Dependence of Bioactivity of Glasses in the System CaO-SiO₂-P₂O₅: Its in Vitro Evaluation Reviewed

C. Ohtsuki, T. Kokubo, K. Takatsuka and T. Yamamuro

J. Ceram. Soc. Japan (Seramikkusu Ronbunshi) Vol. 99 page： 1-6 1991.1

Apatite formation on the surface of Ceravital-type glass-ceramic in the body Reviewed

C. Ohtsuki, H. Kushitani, T. Kokubo, S. Kotani and T. Yamamuro

J. Biomed. Mater. Res. Vol. 25 page： 1363-1370 1991

The bonding behavior of calcite to bone Reviewed

Y. Fujita, T. Yamamuro, T. Nakamura, S. Kotani, C. Ohtsuki and T. Kokubo

J. Biomed. Mater. Res. Vol. 25 page： 991-1003 1991

Bone bonding mechanism of β-tricalcium phosphate Reviewed

S. Kotani, Y. Fujita, T. Kitsugi, T. Nakamura, T. Yamamuro, C. Ohtsuki and T. Kokubo

J. Biomed. Mater. Res. Vol. 25 page： 1303-1315 1991

Difference in Bone Bonding Mechanisms between Surface Active Ceramics & Resorbable Ceramics : Scanning and Transmission Electron Microscopic Study Reviewed

M. Neo, S. Kotani, Y. Fujita, T. Nakamura, T. Yamamuro, Y. Bando, M. Yokoyama, C. Ohtsuki and T. Kokubo

Bioceramics, Vol.4, ed. by W. Bonfiedld, G. W. Hastings and K. E. Tanner, Butterworth-Heinemann, Guilford page： 165-170 1991

Surface Structure of Bioactive Glass-Ceramic A-W Implanted into Sheep and Human Vertebra Reviewed

T. Kokubo, C. Ohtsuki, S. Kotani, T. Kitsugi and T. Yamamuro

Bioceramics, Vol. 2, ed. by G.Heimke, German Ceramic Society, Cologne page： 113-120 1990.9

Bioactivity of Glass-Ceramics Reviewed

T. Kokubo, H. Kushitani, C. Ohtsuki, Y. Ebisawa, T. Kitsugi, K. Oura, S. Kotani and T. Yamamuro

Proceedings of XV International Congress on Glass, Vol.3a, ed. by O. V. Mazurin, Nauka, Leningrad page： 114-119 1989.7

ZrS₂のホットプレス焼結と熱的変化 Reviewed

田中嘉一郎, 三木章伍, 大槻主税, 植月徹, 木島弌倫

材料 Vol. 38 page： 1-7 1989

TiSe_1.6及びTiSe_1.5のホットプレス焼結と熱的変化 Reviewed

田中嘉一郎, 大槻主税, 植月徹, 中沢泰朗

窯業協会誌 Vol. 96 page： 165-170 1988.2

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