International Society of Exposure Science

2011.4

健康食品管理士会

2005.4

日本臨床化学会

2004.4

  動物実験委員会委員  

2011.4 - 2016.3   

  国際交流委員会委員  

2010.4 - 2012.3   

  就職委員  

2006.4 - 2012.3   

奥谷賞

2009.6   奥谷賞選考委員会  

平成２０年度日本衛生学会最優秀論文賞

2009.3   日本衛生学会  

Association Between the Redox State of Human Serum Albumin and Exercise Capacity in Patients With Cardiac Disease Reviewed

Ishimaru, Y; Adachi, T; Ashikawa, H; Hori, M; Shimozato, T; Ohtake, H; Shimizu, S; Ueyama, J; Yamada, S

AMERICAN JOURNAL OF CARDIOLOGY   Vol. 189   page： 56 - 60   2023.2

Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults Reviewed

Ueyama, J; Hayashi, M; Hirayama, M; Nishiwaki, H; Ito, M; Saito, I; Tsuboi, Y; Isobe, T; Ohno, K

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH   Vol. 20 ( 1 )   2023.1

Interpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working group's health-based guidance value (HB2GV) dashboard Reviewed International coauthorship

Nakayama, SF; St-Amand, A; Pollock, T; Apel, P; Bamai, YA; Barr, DB; Bessems, J; Calafat, AM; Castaño, A; Covaci, A; Duca, RC; Faure, S; Galea, KS; Hays, S; Hopf, NB; Ito, Y; Jeddi, MZ; Kolossa-Gehring, M; Kumar, E; LaKind, JS; López, ME; Louro, H; Macey, K; Makris, KC; Melnyk, L; Murawski, A; Naiman, J; Nassif, J; Noisel, N; Poddalgoda, D; Quirós-Alcalá, L; Rafiee, A; Rambaud, L; Silva, MJ; Ueyama, J; Verner, MA; Waras, MN; Werry, K

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH   Vol. 247   page： 114046   2023.1

Gut microbiota in dementia with Lewy bodies Reviewed

Nishiwaki, H; Ueyama, J; Kashihara, K; Ito, M; Hamaguchi, T; Maeda, T; Tsuboi, Y; Katsuno, M; Hirayama, M; Ohno, K

NPJ PARKINSONS DISEASE   Vol. 8 ( 1 ) page： 169   2022.12

Association of Redox State of Human Serum Albumin with Severity in Patients with Heart Failure A Cross-Sectional Study Reviewed

Nishikawa, T; Shimizu, S; Kamiya, H; Ueyama, J; Yamada, S

INTERNATIONAL HEART JOURNAL   Vol. 63 ( 6 ) page： 1107 - 1114   2022.11

Survey of Arsenic/Heavy Metals and Pesticide Residues in Edible Insects for Human Consumption or Supplied in Japan Reviewed

Kitahara Yugo, Nomura Hiroshi, Nishihara Nanami, Ueda Takuya, Watanabe Satoru, Saito Isao, Ueyama Jun

FOOD HYGIENE AND SAFETY SCIENCE   Vol. 63 ( 4 ) page： 136 - 140   2022.8

Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson's disease Reviewed

Nishiwaki Hiroshi, Ito Mikako, Hamaguchi Tomonari, Maeda Tetsuya, Kashihara Kenichi, Tsuboi Yoshio, Ueyama Jun, Yoshida Takumi, Hanada Hiroyuki, Takeuchi Ichiro, Katsuno Masahisa, Hirayama Masaaki, Ohno Kinji

NPJ PARKINSONS DISEASE   Vol. 8 ( 1 ) page： 65   2022.6

Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow development Reviewed

Tamura Shogo, Mukaide Masato, Katsuragi Yumi, Fujii Wataru, Odaira Koya, Suzuki Nobuaki, Tsukiji Nagaharu, Okamoto Shuichi, Suzuki Atsuo, Kanematsu Takeshi, Katsumi Akira, Takagi Akira, Ikeda Katsuhide, Ueyama Jun, Hirayama Masaaki, Suzuki-Inoue Katsue, Matsushita Tadashi, Kojima Tetsuhito, Hayakawa Fumihiko

JOURNAL OF BIOLOGICAL CHEMISTRY   Vol. 298 ( 5 ) page： 101833   2022.5

Simultaneous quantification of pyrethroid metabolites in urine of non-toilet-trained children in Japan Reviewed

Ueyama Jun, Ito Yuki, Hamada Risa, Oya Naoko, Kato Sayaka, Matsuki Taro, Tamada Hazuki, Kaneko Kayo, Saitoh Shinji, Sugiura-Ogasawara Mayumi, Ebara Takeshi, Kamijima Michihiro

ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   Vol. 27 ( 0 ) page： 25   2022

Intestinal <i>Collinsella</i> may mitigate infection and exacerbation of COVID-19 by producing ursodeoxycholate Reviewed

Hirayama, M; Nishiwaki, H; Hamaguchi, T; Ito, M; Ueyama, J; Maeda, T; Kashihara, K; Tsuboi, Y; Ohno, K

PLOS ONE   Vol. 16 ( 11 ) page： e0260451   2021.11

Human Nonmercaptalbumin Is a New Biomarker of Motor Function Reviewed

Ito, S; Nakashima, H; Ando, K; Kobayashi, K; Machino, M; Seki, T; Ishizuka, S; Kanbara, S; Inoue, T; Koshimizu, H; Fujii, R; Yamada, H; Ando, Y; Ueyama, J; Kondo, T; Suzuki, K; Hasegawa, Y; Imagama, S

JOURNAL OF CLINICAL MEDICINE   Vol. 10 ( 11 )   2021.6

Association of self-reported moderate vegetable juice intake with small decline in kidney function in a five-year prospective study. Reviewed

Fujii R, Kondo T, Tsukamoto M, Kawai S, Sasakabe T, Naito M, Kubo Y, Okada R, Tamura T, Hishida A, Ueyama J, Hayashi Y, Ohnishi J, Hamajima N, Takeuchi K, Wakai K

Nutrition (Burbank, Los Angeles County, Calif.)   Vol. 84   page： 111114   2021.4

Non-linear model analysis of the relationship between cholinesterase activity in rats exposed to 2, 2-dichlorovinyl dimethylphosphate (dichlorvos) and its metabolite concentrations in urine Reviewed

Sato, H; Ito, Y; Hanai, C; Nishimura, M; Ueyama, J; Kamijima, M

TOXICOLOGY   Vol. 450   page： 152679   2021.2

Cumulative exposure assessment of neonicotinoids and an investigation into their intake-related factors in young children in Japan. Reviewed

Oya N, Ito Y, Ebara T, Kato S, Ueyama J, Aoi A, Nomasa K, Sato H, Matsuki T, Sugiura-Ogasawara M, Saitoh S, Kamijima M

The Science of the total environment   Vol. 750   page： 141630   2021.1

Occupational exposure limits for acetaldehyde, 2-bromopropane, glyphosate, manganese and inorganic manganese compounds, and zinc oxide nanoparticle, and the biological exposure indices for cadmium and cadmium compounds and ethylbenzene, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications Invited Reviewed

Araki, A; Azuma, K; Endo, G; Endo, Y; Fukushima, T; Hara, K; Harada, K; Hori, H; Horie, S; Horiguchi, H; Ichiba, M; Ichihara, G; Ishitake, T; Ito, A; Ito, Y; Iwasawa, S; Kakamu, T; Kamijima, M; Karita, K; Kawai, T; Kawamoto, T; Kishi, R; Kumagai, S; Matsumoto, A; Miyagawa, M; Miyauchi, H; Morimoto, Y; Nagano, K; Naito, H; Nakajima, T; Nakano, M; Nomiyama, T; Okuda, H; Okuda, M; Omae, K; Sato, K; Sobue, T; Suwazono, Y; Takebayashi, T; Takeshita, T; Takeuchi, A; Takeuchi, A; Tanaka, S; Tsuji, M; Tsukahara, T; Ueno, S; Ueyama, J; Umeda, Y; Yamamoto, K; Yamano, Y; Yamauchi, T; Yano, E

JOURNAL OF OCCUPATIONAL HEALTH   Vol. 63 ( 1 )   2021.1

Optimization and validation of a highly sensitive method for determining glyphosate in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: a methodological study Reviewed

ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   Vol. 25 ( 1 ) page： 83   2020.12

Short-Chain Fatty Acid-Producing Gut Microbiota Is Decreased in Parkinson's Disease but Not in Rapid-Eye-Movement Sleep Behavior Disorder. Reviewed

Nishiwaki H, Hamaguchi T, Ito M, Ishida T, Maeda T, Kashihara K, Tsuboi Y, Ueyama J, Shimamura T, Mori H, Kurokawa K, Katsuno M, Hirayama M, Ohno K

mSystems   Vol. 5 ( 6 )   2020.11

Meta-Analysisof Gut Dysbiosis in Parkinson's Disease Reviewed

Nishiwaki Hiroshi, Ito Mikako, Ishida Tomohiro, Hamaguchi Tomonari, Maeda Tetsuya, Kashihara Kenichi, Tsuboi Yoshio, Ueyama Jun, Shimamura Teppei, Mori Hiroshi, Kurokawa Ken, Katsuno Masahisa, Hirayama Masaaki, Ohno Kinji

MOVEMENT DISORDERS   Vol. 35 ( 9 ) page： 1626 - 1635   2020.9

Within-individual and interlaboratory variability analyses of urinary metabolites measurements of organophosphorus insecticides Reviewed

Ito Yuki, Ueyama Jun, Nakayama Shoji F., Isobe Tomohiko, Oya Naoko, Sato Hirotaka, Ebara Takeshi, Yoshimasu Kouichi, Tsuno Kanami, Tatsuta Nozomi, Nakai Kunihiko, Kamijima Michihiro

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY   Vol. 30 ( 4 ) page： 721 - 729   2020.7

Within-individual and interlaboratory variability analyses of urinary metabolites measurements of organophosphorus insecticides Reviewed

Yuki Ito, Jun Ueyama, Shoji F Nakayama, Tomohiko Isobe, Naoko Oya, Hirotaka Sato, Takeshi Ebara, Kouichi Yoshimasu, Kanami Tsuno, Nozomi Tatsuta, Kunihiko Nakai, Michihiro Kamijima

J Expo Sci Environ Epidemiol   Vol. 30 ( 4 ) page： 721 - 729   2020.7

Associations between Exposure to Tobacco Smoke and Behavioral Problems in Preschool Japanese Children Reviewed

Wada Keiko, Ueyama Jun, Konishi Kie, Goto Yuko, Koda Sachi, Mizuta Fumi, Tamura Takashi, Watanabe Kaori, Ando Kyoko, Kondo Takaaki, Nagata Chisato

JOURNAL OF ENVIRONMENTAL AND PUBLIC HEALTH   Vol. 2020   page： 7591263   2020.5

Association between redox state of human serum albumin and exercise capacity in older women: A cross-sectional study Reviewed

Ashikawa Hironobu, Adachi Takuji, Ueyama Jun, Yamada Sumio

GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 20 ( 3 ) page： 256 - 260   2020.3

Ten-year temporal trends (2006-2015) and seasonal-differences in urinary metabolite concentrations of novel, hygiene-used pyrethroids in Japanese children. Reviewed

Hamada R, Ueda Y, Wada K, Saito I, Nomura H, Kamijima M, Nakane K, Nagata C, Kondo T, Ueyama J.

Int J Hyg Environ Health   Vol. 225   page： 113448   2020.1

Occupational exposure limits for ethyl benzene, dimethyl terephthalate and hydrogen fluoride, and carcinogenicity and reproductive toxicant classifications The Committee for Recommendation of Occupational Exposure Limits, Japan Society for Occupational Health

Araki Atsuko, Azuma Kenichi, Endo Ginji, Endo Yoko, Fukushima Tetsuhito, Hara Kunio, Hori Hajime, Ichiba Masayoshi, Ishitake Tatsuya, Ichihara Gaku, Ito Akiyoshi, Ito Yuki, Iwasawa Satoko, Kakamu Takeyasu, Kamijima Michihiro, Karita Kanae, Katoh Takahiko, Kawai Toshio, Kawamoto Toshihiro, Kishi Reiko, Kumagai Shinji, Kusaka Yukinori, Miyagawa Muneyuki, Miyauchi Hiroyuki, Morimoto Yasuo, Nagano Kasuke, Naito Hisao, Nakajima Tamie, Nakano Makiko, Nomiyama Tetsuo, Okuda Hirokazu, Okuda Masayuki, Omae Kazuyuki, Sato Kazuhiro, Sobue Tomotaka, Suwazono Yasushi, Takebayashi Toru, Takeshita Tatsuya, Tsukahara Teruomi, Tsunoda Masashi, Ueyama Jun, Umeda Yumi, Yamamoto Kenya, Yamano Yuko, Yamauchi Takenori, Yano Eiji

JOURNAL OF OCCUPATIONAL HEALTH   Vol. 62 ( 1 )   2020.1

Biomonitoring method for neonicotinoid insecticides in urine of non-toilet-trained children using LC-MS/MS.

Ueyama J, Aoi A, Ueda Y, Oya N, Sugiura Y, Ito Y, Ebara T, Kamijima M

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     page： 1-12   2019.12

Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China.

Wang Y, Zhang Y, Ji L, Zhou Y, Shi R, Kamijima M, Ueyama J, Gao Y, Tian Y

Environmental science and pollution research international     2019.11

Freeze-drying enables homogeneous and stable sample preparation for determination of fecal short-chain fatty acids.

Ueyama J, Oda M, Hirayama M, Sugitate K, Sakui N, Hamada R, Ito M, Saito I, Ohno K

Analytical biochemistry     page： 113508   2019.11

Exposure levels of organophosphate pesticides in Japanese diapered children: Contributions of exposure-related behaviors and mothers' considerations of food selection and preparation.

Oya N, Ito Y, Ebara T, Kato S, Hioki K, Aoi A, Ueyama J, Oguri T, Shoji N, Sugiura-Ogasawara M, Saitoh S, Kamijima M

Environment international   Vol. 134   page： 105294   2019.11

Cohort profile: Aichi regional sub-cohort of the Japan Environment and Children's Study (JECS-A) Reviewed

Takeshi Ebara, Yasuyuki Yamada, Naoto Shoji, Yuki Ito, Atsuko Nakagawa, Taishi Miyachi, Yasuhiko Ozaki, Toyonori Omori, Sadao Suzuki, Masayo Kojima, Jun Ueyama, Motohiro Tomizawa, Sayaka Kato, Tomoko Oguri, Taro Matsuki, Hirotaka Sato, Naoko Oya, Mayumi Sugiura-Ogasawara, Shinji Saitoh, Michihiro Kamijima

BMJ Open   Vol. 9 ( 11 ) page： e028105   2019.11

Occupational exposure limits for cumene, 2,4-dichlorophenoxy acetic acid, silicon carbide whisker, benzyl alcohol, and methylamine, and carcinogenicity, occupational sensitizer, and reproductive toxicant classifications

Araki Atsuko, Azuma Kenichi, Endo Ginji, Endo Yoko, Fukushima Tetsuhito, Hara Kunio, Harada Koji, Hori Hajime, Horie Seichi, Ichiba Masayoshi, Ichihara Gaku, Ikeda Masayuki, Ito Akiyoshi, Ito Yuki, Iwasawa Satoko, Kakumu Takeyasu, Kamijima Michihiro, Karita Kanae, Katoh Takahiko, Kawai Toshio, Kawamoto Toshihiro, Kumagai Shinji, Kusaka Yukinori, Matsumoto Akiko, Miyagawa Muneyuki, Miyauchi Hiroyuki, Morimoto Yasuo, Nagano Kasuke, Naito Hisao, Nakajima Tamie, Nakano Makiko, Nomiyama Tetsuo, Okuda Hirokazu, Okuda Masayuki, Omae Kazuyuki, Sakurai Haruhiko, Sato Kazuhiro, Sobue Tomotaka, Suwazono Yasushi, Takebayashi Toru, Takeshita Tatsuya, Takeuchi Akito, Takeuchi Ayano, Tanaka Masatoshi, Tanaka Shigeru, Tsukahara Teruomi, Tsunoda Masashi, Ueno Susumu, Ueyama Jun, Umeda Yumi, Yamamoto Kenya, Yamano Yuko, Yamauchi Takenori, Yano Eiji

JOURNAL OF OCCUPATIONAL HEALTH   Vol. 61 ( 4 ) page： 328 - 330   2019.7

Association between exposure to household smoking and dental caries in preschool children: a cross-sectional study.

Goto Y, Wada K, Konishi K, Uji T, Koda S, Mizuta F, Yamakawa M, Watanabe K, Ando K, Ueyama J, Kondo T, Nagata C

Environmental health and preventive medicine   Vol. 24 ( 1 ) page： 9   2019.1

Intra-individual variations of organophosphate pesticide metabolite concentrations in repeatedly collected urine samples from pregnant women in Japan.

Hioki K, Ito Y, Oya N, Nakayama SF, Isobe T, Ebara T, Shibata K, Nishikawa N, Nakai K, Kamida T, Ueyama J, Sugiura-Ogasawara M, Kamijima M

Environmental health and preventive medicine   Vol. 24 ( 1 ) page： 7   2019.1

Human Serum Albumin Redox State is Associated with Decreased Renal Function in a Community-Dwelling Population.

Fujii R, Ueyama J, Kanno T, Suzuki K, Hamajima N, Wakai K, Hasegawa Y, Kondo T

American journal of physiology. Renal physiology     2018.11

A sensitive and efficient procedure for the high-throughput determination of nine urinary metabolites of pyrethroids by GC-MS/MS and its application in a sample of Japanese children

Ueda Yuko, Oda Masaya, Saito Isao, Hamada Risa, Kondo Takaaki, Kamijima Michihiro, Ueyama Jun

ANALYTICAL AND BIOANALYTICAL CHEMISTRY   Vol. 410 ( 24 ) page： 6207 - 6217   2018.9

A new method for simultaneous quantification of fosphenytoin, phenytoin and its primary metabolite 5-(4-hydroxyphenyl)-5-phenylhydantoin in whole blood by ultra-performance liquid chromatography-tandem mass spectrometry.

Suzuki T, Ogawa T, Ueyama J, Iwai M, Kondo F, Seno H

Legal medicine (Tokyo, Japan)   Vol. 34   page： 64-69   2018.9

Occupational Exposure Limits for ethylidene norbornene, ethyleneimine, benomyl, and 2,3-epoxypropyl methacrylate, and classifications on carcinogenicity

Araki Atsuko, Azuma Kenichi, Endo Ginji, Endo Yoko, Fukushima Tetsuhito, Hara Kunio, Hori Hajime, Horie Seichi, Horiguchi Hyogo, Ichiba Masayoshi, Ichihara Gaku, Ikeda Masayuki, Ishitake Tatsuya, Ito Akiyoshi, Ito Yuki, Iwasawa Satoko, Kakumu Takeyasu, Kamijima Michihiro, Karita Kanae, Katoh Takahiko, Kawai Toshio, Kawamoto Toshihiro, Kumagai Shinji, Kusaka Yukinori, Matsumoto Akiko, Miyagawa Muneyuki, Miyauchi Hiroyuki, Morimoto Yasuo, Nagano Kasuke, Naito Hisao, Nakajima Tamie, Nakano Makiko, Nomiyama Tetsuo, Okuda Hirokazu, Okuda Masayuki, Omae Kazuyuki, Sakurai Haruhiko, Sato Kazuhiro, Sobue Tomotaka, Suwazono Yasushi, Takebayashi Toru, Takeshita Tatsuya, Takeuchi Akito, Takeuchi Ayano, Tanaka Masatoshi, Tanaka Shigeru, Tsukahara Teruomi, Tsunoda Masashi, Ueno Susumu, Ueyama Jun, Umeda Yumi, Yamamoto Kenya, Yamano Yuko, Yamauchi Takenori, Yano Eiji

JOURNAL OF OCCUPATIONAL HEALTH   Vol. 60 ( 4 ) page： 333 - 335   2018.7

Common variant of BCAS3 is associated with gout risk in Japanese population: the first replication study after gout GWAS in Han Chinese

Sakiyama Masayuki, Matsuo Hirotaka, Nakaoka Hirofumi, Kawamura Yusuke, Kawaguchi Makoto, Higashino Toshihide, Nakayama Akiyoshi, Akashi Airi, Ueyama Jun, Kondo Takaaki, Wakai Kenji, Sakurai Yutaka, Yamamoto Ken, Ooyama Hiroshi, Shinomiya Nariyoshi

BMC MEDICAL GENETICS   Vol. 19 ( 1 ) page： 96   2018.6

Effects of processing and cooking on the reduction of dinotefuran concentration in Japanese rice samples.

Watanabe M, Ueyama J, Ueno E, Ueda Y, Oda M, Umemura Y, Tanahashi T, Ikai Y, Saito I

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     2018.3

Oxidized human serum albumin as a possible correlation factor for atherosclerosis in a rural Japanese population: the results of the Yakumo Study

Fujii Ryosuke, Ueyama Jun, Aoi Arisa, Ichino Naohiro, Osakabe Keisuke, Sugimoto Keiko, Suzuki Koji, Hamajima Nobuyuki, Wakai Kenji, Kondo Takaaki

ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   Vol. 23 ( 1 ) page： 1   2018.1

Human Biomonitoring as a Useful Approach to Health Risk Assessment Compared with Occupational Exposure Assessment of Insecticide Intake: Fundamental Study Focused on Local Populations and Occupational Fields Invited Reviewed

Jun Ueyama

Nihon Eiseigaku Zasshi   Vol. 73 ( 3 ) page： 247 - 256   2018

(-)-Epigallocatechin-3-gallate Down-regulates Doxorubicin-induced Overexpression of P-glycoprotein Through the Coordinate Inhibition of PI3K/Akt and MEK/ERK Signaling Pathways. Reviewed

HANA SATONAKA, KUMIKI ISHIDA, MIHO TAKAI, RYOJI KOIDE, RYOTA SHIGEMASA, JUN UEYAMA, TETSUYA ISHIKAWA, KAZUHIKO HAYASHI, HIDEMI GOTO and SHINYA WAKUSAWA

Anticancer Res   Vol. 37 ( 11 ) page： 6071-6077   2017.11

Nitric Oxide Plasma Level as a Barometer of Endothelial Dysfunction in Factory Workers

Miyata Seiko, Noda Akiko, Hara Yuki, Ueyama Jun, Kitaichi Kiyoyuki, Kondo Takaaki, Koike Yasuo

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES   Vol. 125 ( 10 ) page： 684 - 689   2017.11

Association Between Organophosphate Pesticide Exposure and Thyroid Hormones in Pregnant Women. Reviewed

Yiwen Wang; Limei Chen; Caifeng Wang; Yi Hum; Yu Gao; Yijun Zhou; Rong Shi; Yan Zhang; Michihiro Kamijima; Jun Ueyama; Ying Tian

Epidemiology   Vol. 2017 ( 28 ) page： S35–S40   2017.10

Prenatal and postnatal exposure to organophosphate pesticides and childhood neurodevelopment in Shandong, China Reviewed

Yiwen Wang, Yan Zhang, Lin Ji, YiHu, Jingjing Zhang, Caifeng Wang, Guodong Ding, Limei Chen, Michihiro Kamijima, Jun Ueyama, Yu Gao c, Ying Tian

Environment International   Vol. 108   page： 119-126   2017.8

Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. Invited Reviewed

Kenichi Azuma, Ginji Endo, Yoko Endo, Tetsuhito Fukushima, Kunio Hara, Hajime Hori, Seichi Horie, Hyogo Horiguchi, Masayoshi Ichiba, Gaku Ichihara, Masayuki Ikeda, Tatsuya Ishitake, Akiyoshi Ito, Yuki Ito, Satoko Iwasawa, Michihiro Kamijima, Kanae Karita, Takahiko Katoh, Toshio Kawai, Toshihiro Kawamoto, Reiko Kishi, Shinji Kumagai, Yukinori Kusaka, Akiko Matsumoto, Muneyuki Miyagawa, Hiroyuki Miyauchi, Yasuo Morimoto, Kasuke Nagano, Hisao Naito, Tamie Nakajima, Tetsuo Nomiyama, Hirokazu Okuda, Kazuyuki Omae, Haruhiko Sakurai, Kazuhiro Sato, Tomotaka Sobue, Yasushi Suwazono, Toru Takebayashi, Tatsuya Takeshita, Akito Takeuchi, Ayano Takeuchi, Masatoshi Tanaka, Shigeru Tanaka, Teruomi Tsukahara, Masashi Tsunoda, Susumu Ueno, Jun Ueyama, Yumi Umeda, Yuko Yamano, Takenori Yamauchi and Eiji Yano

J Occup Health   Vol. 59 ( 4 ) page： 364-366   2017.6

Quantitative analysis of organophosphate insecticide metabolites in urine extracted from disposable diapers of toddlers in Japan. Reviewed

NaokoOya, Yuki Ito, Keisuke Hioki, Yuya Asai, Arisa Aoi, Yuka Sugiura, Jun Ueyama, Tomoko Oguri, Sayaka Kato, Takeshi Ebara, Michihiro Kamijima

International Journal of Hygiene and Environmental Health   Vol. 220 ( 2 ) page： 209 - 216   2017.3

Modulation of immunological activity on macrophages induced by diazinon. Reviewed

Nanako Ogasawara, Miyoko Matsushima, Nami Kawamura, Kazuko Atsumi, Takehiro Yamaguchi, Haruka Ochi, Yuto Kusatsugu, Sayaka Oyabu, Naozumi Hashimoto, Yoshinori Hasegawa, Jun Ueyama, Tsutomu Kawabe

Toxicology   Vol. 379   page： 22-30   2017.1

Exposure characterization of three major insecticide lines in urine of young children in Japan-neonicotinoids, organophosphates, and pyrethroids. Reviewed

Osaka A, Ueyama J, Kondo T, Nomura H, Sugiura Y, Saito I, Nakane K, Takaishi A, Ogi H, Wakusawa S, Ito Y, Kamijima M.

Environmental Research   Vol. 147   page： 89-96   2016.5

Temporal Levels of Urinary Neonicotinoid and Diaklyphosphate Concentrations in Japanese Women Between 1994-2011 Reviewed

Jun Ueyama, Kouji H Harada, Akio Koizumi, Yuka Sugiura, Takaaki Kondo, Isao Saito, and Michihiro Kamijima

Environmental Science & Tachinology   Vol. 49 ( 24 ) page： 14522-14528   2015.12

Effects of Paraoxonase 1 gene polymorphisms on organophosphate insecticide metabolism in Japanese pest control workers. Reviewed

Sato H, Ito Y, Ueyama J, Kano Y, Arakawa T, Gotoh M, Kondo T, Sugiura Y, Saito I, Shibata E, Kamijima M.

Journal of Occupational Health   Vol. 58 ( 1 ) page： 56-65   2015.12

Lack of contribution of multidrug resistance-associated protein and organic anion-transporting polypeptide to pharmacokinetics of Regorafenib, a novel multi-kinase inhibitor, in rats. Reviewed

HOTTA Kazuo, UEYAMA Jun, TATSUMI Yasuaki, YSUKIYAMA Ikuto, SUGIURA Yuka, SAITO Hiroko, MATSUURA Katsuhiko, HASEGAWA Takaaki

Anticancer Res   Vol. 35 ( 9 ) page： 4681-4689   2015.9

Comparison of different urine pretreatments for biological monitoring of pyrethroid insecticides. Reviewed

TOSHIMA Hiroki, YOSHINAGA Jun, SHIRAISHI Hiroaki, ITO Yuki, KAMIJIMA Michihiro, UEYAMA Jun

Journal of Analytical Toxicology   Vol. 39 ( 2 ) page： 133-136   2015.3

Biological Monitoring Method for Urinary Neonicotinoid Insecticides Using LC-MS/MS and Its Application to Japanese Adults. Reviewed

UEYAMA Jun, NOMURA Hiroshi, KONDO Takaaki, SAITO Isao, ITO Yuki, OSAKA Aya, KAMIJIMA Michihiro

Journal of Occupational Health   Vol. 56   page： 461-468   2015.1

A revised method for determination of dialkylphosphate levels in human urine by solid-phase extraction and liquid chromatography with tandem mass spectrometry: application to human urine samples from Japanese children. Reviewed

UEYAMA Jun, SAITO Isao, TAKAISHI Akiko, NOMURA Hiroshi, NOUE Mai, OSAKA Aya, SUGIURA Yuka, HAYASHI Yumi, WAKUSAWA Shinya, OGI Hiroko, INUZUKA Kimio, KAMIJIMA Michihiro, KONDO Takaaki

Environmental Health and Preventive Medicine   Vol. 19 ( 6 ) page： 405-413   2014.11

Contribution of plasma proteins, albumin and alpha 1-acid glycoprotein, to pharmacokinetics of a multi-targeted receptor tyrosine kinase inhibitor, sunitinib, in analbuminemic rats. Reviewed

TOYAMA Yukio, UEYAMA Jun, NOMURA Hiroshi, TSUKIYAMA Ikuto, SAITO Hiroko, HISADA Tatsuya, MATSUURA Katsuhiko, HASEGAWA Takaaki

Anticancer Res   Vol. 34 ( 5 ) page： 2283-2289   2014.6

A non-invasive biomonitoring method for assessing levels of urinary pyrethroid metabolites in diapered children by gas chromatography-mass spectrometry. Reviewed

SAITO Shun, UEYAMA Jun, KONDO Takaaki, SAITO Isao, SHIBATA Eiji, GOTOH Masahiro, NOMURA Hiroshi, WAKUSAWA Shinya, NAKAI Kunihiko, KAMIJIMA Michihiro.

J Expo Sci Environ Epidemiol   Vol. 24 ( 2 ) page： 200-7   2014.3

A revised method for determination of serum mercaptalbumin and nonmercaptalbumin by high performance liquid chromatography coupled with post-column bromocresol green reaction. Reviewed

UEYAMA Jun, ISHIKAWA Yusuke, KONDO Takaaki, MOTOYAMA Megumi, MATSUMOTO Hiroyuki, MATSUSHITA Tadashi

Ann Clin Biochem.   Vol. in press   page： in press   2014.3

Biochemical staging of the chronic hepatic lesions of Wilson disease. Reviewed

Katano Y, Hayashi K, Hattori A, Tatsumi Y, Ueyama J, Wakusawa S, Yano M, Toyoda H, Kumada T, Mizutani N, Hayashi H, Goto H.

Nagoya J Med Sci.   Vol. 76 ( 1-2 ) page： 139-148   2014.2

Ursodeoxycholic acid inhibits overexpression of P-glycoprotein induced by doxorubicin in HepG2 cells. Reviewed

Komori Y, Arisawa S, Takai M, Yokoyama K, Honda M, Hayashi K, Ishigami M, Katano Y, Goto H, Ueyama J, Ishikawa T, Wakusawa S.

Eur J Pharmacol.   Vol. 724   page： 161-167   2014.2

Quantitation of neonicotinoid metabolites in human urine using GC-MS. Reviewed

NOMURA Hiroshi, UEYAMA Jun, KONDO Takaaki, SAITO Isao, MURATA Katsuyuki, IWATA Toyoto, WAKUSAWA Shinya, KAMIJIMA Michihiro

Journal of Chromatography B   Vol. 941   page： 109-115   2013.12

Drug interaction between sunitinib and cimetidine and contribution of the efflux transporter ATP-binding cassette C2 to biliary excretion of sunitinib in rats. Reviewed

ARAKAWA-TODO Mika, UEYAMA Jun, NOMURA Hiroshi, ABE Fumie, TSUKIYAMA Ikuto, MATSUURA Katsuhiko, HASEGAWA Takaaki

Anticancer Research   Vol. 33 ( 8 ) page： 3089-3097   2013.8

Preparation of dealcholized onetaxotere®, docetaxel injection formulation and its pharmacokinetics in rats. Reviewed

Onishi Katsuhiro, TSUKIYAMA Ikuto, UEYAMA Jun, ABE Fumie, SAITO Hiroko, MATSUURA Katsuhiko, NADAI Masayuki, HASEGAWA Takaaki

Gan To Kagaku Ryoho.   Vol. 40 ( 7 ) page： 891-986   2013.7

Various copper and iron overload patterns in the livers of patients with Wilson disease and idiopathic copper toxicosis Reviewed

HAYASHI Hisao, HATTORI Ai, TATSUMI Yasuaki, HAYASHI Kazuhiko, KATANO Yoshiaki, UEYAMA Jun, WAKUSAWA Shinya, YANO Motoyoshi, GOTO Hidemi

Med Mol Morphol.   Vol. 22   page： 00-00   2013.1

Evidence for diazinon-mediated inhibition of cis-permethrin metabolism and its effects on reproductive toxicity in adult male mice Reviewed

WANG Dong, KAMIJIMA Michihiro, OKAMURA Ai, ITO Yuki, YANAGIBA Yukie, JIA Xiao-fang, NAITO Hisao, UEYAMA Jun, NAKAJIMA Tamie

Reprod Toxicol.   Vol. 34   page： 489-497   2012.12

Urinary concentrations of organophosphorus insecticide metabolites in Japanese workers Reviewed

UEYAMA Jun, SAITO Isao, KONDO Takaaki, TAKI Tomoko, KIMATA Akiko, SAITO Shun, ITO Yuki, MURATA Katsuyuki, IWATA Toyoto, GOTOH Masahiro, SHIBATA Eiji, WAKUSAWA Shinya, KAMIJIMA Michihiro

Chemosphere   Vol. 87   page： 1403-1409   2012.6

Prevalence of Helicobacter Pylori Infection Measured with Urinary Antibody in an Urban Area of Japan, 2008-2010 Reviewed

TAMURA Takashi, MORITA Emi, KONDO Takaaki, UEYAMA Jun, TANAKA Tetsuya, KIDA Yuto, HORI Yoko, INOUE Shigeru, TOMITA Koutaro, OKADA Rieko, KAWAI Sayo, HISHIDA Asahi, NAITO Mariko, WAKAI Kenji and HAMAJIMA Nobuyuki

Nagoya Journal of Medical Science   Vol. 74   page： 63-70   2012.2

New analytical method for sensitive quantification of urinary 3-methyl-4-nitrophenol to assess fenitrothion exposure in general population and occupational sprayers Reviewed

OKAMURA Ai, SAITO Isao, UEYAMA Jun, ITO Yuki, NAKAJIMA Tamie, KAMIJIMA Michihiro

Toxicol Lett.   Vol. 210 ( 2 ) page： 220-224   2011.11

Panipenem does not alter the pharmacokinetics of the active metabolite of irinotecan SN-38 and inactive metabolite SN-38 glucuronide (SN-38G) in rats Reviewed

KATO Ayako, UEYAMA Jun, ABE Fumie, HOTTA Kazuo, TSUKIYAMA Ikuo, OSHIMA Taeyuki, KONDO F, SAITO Hiroko, HASEGAWA Takaaki.

Anticancer Res.   Vol. 31 ( 9 ) page： 2915-2922   2011.9

Study Profile on Baseline Survey of Daiko Study in the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) Reviewed

MORITA Emi, HAMAJIMA Nobuyuki, HISHIDA Asahi, AOYAMA Kyoko, OKADA Rieko, KAWAI Sayo, TOMITA Koutaro, KURIKI Sayaka, TAMURA Takashi, NAITO Mariko, KONDO Takaaki, UEYAMA Jun, KIMATA Akiko, YAMAMOTO Kanami, HORI Yoko, HOSHINO Junko, HAMAMOTO Ritsuko, TSUKAMOTO Sanae, ONISHI Johji, HAGIKURA Shoichi, NAITO Hisao, HIBI Satoshi, ITO Yoshinori and WAKAI Kenji

Nagoya Journal of Medical Science   Vol. 73   page： 187-195   2011.8

Effect of DDVP on urinary excretion levels of pyrethroid metabolite 3-phenoxybenzoic acid in rats Reviewed

HIROSAWA Naoko, UEYAMA Jun, KONDO Takaaki, KAMIJIMA Michihiro, TAKAGI Kenji, FUJINAKA Sanae, HIRATE Ayaka, HASEGAWA Takaaki, WAKUSAWA Shinya.

Toxicol Lett.   Vol. 203 ( 1 ) page： 28-32   2011.4

Mechanism underlying the efficacy of combination therapy with losartan and hydrochlorothiazide in rats with salt-sensitive hypertension. Reviewed

YAMADA Yuichiro, TSUBOI Koji, HATTORI Takuya, MURATE Takashi, OHTAKE Masafumi, FRUKAWA Mayuko, UEYAMA Jun, NISHIYAMA Akira, MUROHARA Toyoaki, NAGATA Kohzo.

Hypertens Res   Vol. 34 ( 7 ) page： 809-816   2011.4

Association of UGT1A1 Gly71Arg with urine urobilinogen Reviewed

KATAOKA Ryuji, KIMATA Akiko, YAMAMOTO Kanami, HIROSAWA Naoko, UEYAMA Jun, KONDO Takaaki, OKADA Rieko, KAWAI Sayo, HISHIDA Asahi, NAITO Mariko, MORITA Emi, WAKITA Kenji, HAMAJIMA Nobuyuki

Nagoya Journal of Medical Science   Vol. 73 ( 1-2 ) page： 33-40   2011.4

Involvement of sulfate conjugation and multidrug resistance-associated protein 2 (MRP2) in sex-related differences in the pharmacokinetics of garenoxacin in rats Reviewed

HAYASHI Tamon, ABE Fumie, KATO Miki, SAITO Hiroko, UEYAMA Jun, KONDO Yuya, IMAI Kuniyuki, KATOH Miki, NADAI Masayuki, HASEGAWA Takaaki

J Infect Chemother   Vol. 17 ( 1 ) page： 24-29   2011.2

Beta-glucuronidase activity is a more sensitive biomarker than cholinesterase inhibition for organophosphorus insecticide exposure Reviewed

UEYAMA Jun, SATOH Tetsuo, KONDO Takaaki, TAKAGI Kenji, SHIBATA Eiji, GOTO Masahiro, KIMATA Akiko, SAITO Isao, HASEGAWA Takaaki, WAKUSAWA Shinya, KAMIJIMA Michihiro.

Toxicol Lett   Vol. 193 ( 1 ) page： 115-119   2010.12

Endotoxin does not alter the pharmacokinetics of micafungin,but it impairs biliary excretion of micafungin via multidrugresistance-associated protein 2 (ABCC2/Mrp2) in rats Reviewed

NODA Takayuki, ABE Fumie, UEYAMA Jun, KATO Miki, KATOH Miki, NADAI Masayuki, SAITO Hiroko, HASEGAWA Takaaki

J Infect Chemother     2010.9

Preliminary study on spontaneous hepatitis in long-evans cinnamon rats: a blood echange may improve the fetal hepatitis Reviewed

UEYAMA Jun, WAKUSAWA Shinya, TATSUMI Yasuyuki, HATTOEI Ai, YANO Motoyoshi, HAYASHI Hisao

Nagoya J Med Sci   Vol. 72 ( 3-4 ) page： 173-177   2010.8

Toxicokinetics of pyrethroid metabolites in male and female rats Reviewed

UEYAMA Jun, HIROSAWA Naoko, MOCHIZUKI Aiko, KIMATA Akiko, KAMIJIMA Michihiro, KONDO Takaaki, TAKAGI Kenji, WAKUSAWA Shinya, HASEGAWA Takaaki

Environmental Toxicology and Pharmacology   Vol. 30 ( 1 ) page： 88-91   2010.7

Revised method for routine determination of urinary dialkyl phosphates using gas chromatography-mass spectrometry Invited Reviewed

UEYAMA Jun, KAMIJIMA Michihiro, KONDO Takaaki, TAKAGI Kenji, SHIBATA Eiji, HASEGAWA Takaaki, WAKUSAWA Shinya, TAKI Tomoko, GOTO Masahiro, SAITO Isao

J Chromatogra B   Vol. 878 ( 17-18 ) page： 1257-1263   2010.5

Analysis and evaluation of pyrethroid exposure in human population based on biological monitoring of urinary pyrethroid metabolites Reviewed

UEYAMA Jun, SAITO Isao, KAMIJIMA Michihiro

Journal of Pesticide Science   Vol. 35 ( 2 ) page： 87-98   2010.4

健常成人における成熟にんにくの血管内皮機能へ及ぼす影響 Reviewed

宮田聖子、野田明子、永井万由佳、大嶽正文、上山純、古池保雄

日本臨床生理学会雑誌   Vol. 40 ( 2 ) page： 103-108   2010.4

Measurement of forearm blood flow of healthy young men and women using strain-gauge plethysmography Reviewed

KONDO Takaaki, YAMADA Chie, FURUTA Takako, YOSHITAKE Junko, SHIROTORI AYA, OKADA Yoshiko, KIMATA Akiko, YAMAMOTO Kanami, UEYAMA Jun, SAKAKIBARA Hisataka, FUKAYA Yukio

Bull Aichi Bunkyo Women's Coll   Vol. 31   page： 27-34   2010.3

Comparison of urinary concentrations of 3-phenoxybenzoic acid among general residents in rural and suburban areas and employees of pest control firms Reviewed

KIMATA Akiko, KONDO Takaaki, UEYAMA Jun, YAMAMOTO K, YOSHITAKE Junko, TAKAGI Kenji, SUZUKI Koji, INOUE Takashi, ITO Yoshinori, HAMAJIMA Nobuyuki, KAMIJIMA Michihiro, GOTOH Masahiro, SHIBATA Eiji.

Int Arch Occup Environ Health   Vol. 82 ( 10 ) page： 1173-1178   2009.11

Broken sperm, cytoplasmic droplets and reduced sperm motility are principal markers of decreased sperm quality due to organophosphorus pesticides in rats Reviewed

OKAMURA Ai, KAMIJIMA Michihiro, OHTANI Katsumi, YAMANOSHITA Osamu, NAKAMURA Daichi, ITO Yuki, MIYATA Maiko, UEYAMA Jun, SUZUKI Takayoshi, IMAI Ryota, TAKAGI Kenji, NAKAJIMA Tamie.

J Occup Health   Vol. 51 ( 6 ) page： 478-487   2009.9

Relationship between dietary habits and urinary concentrations of 3-phenoxybonzoic acid in a middle-aged and elderly general population in Japan Reviewed

KIMATA Akiko, KONDO Takaaki, UEYAMA Jun, YAMAMOTO Kanami, KAMIJIMA Michihiro, SUZUKI Koji INOUE Takashi, ITO Yoshinori, HAMAJIMA Nobuyuki.

Environ Health Prev Med   Vol. 14 ( 3 ) page： 173-179   2009.5

Possible involvement of interleukin-6 (IL-6) in down-regulation of hepatic breast cancer resistance protein (Bcrp/ABCG2) in endotoxemic mice Reviewed

ZHAO Ying Lan, CEN X, ABE Fumie, UEYAMA Jun, HOTTA K, KATO S, ITO S, SAGA S, FUKAYA Yukio, WANG L, WEI Y, HASEGAWA Takaaki

Bull Aichi Bunkyo Women's Coll   Vol. 30   page： 27-42   2009.3

Multilevel analyses of effects of variation in body mass index on serum lipid concentrations in middle-aged Japanese men Reviewed

KONDO Takaaki, KIMATA Akiko, YAMAMOTO Kanami, UEYAMA Sayoko, UEYAMA Jun, Yatsuya H, TAMAKOSHI K, HORI Yoko

Nagoya J Med Sci.   Vol. 71 ( 1-2 ) page： 19-28   2009.2

Urinary excretion of 3-phenoxybenzoic acid in middle-aged and elderly general population of Japan Reviewed

UEYAMA Jun, KIMATA Akiko, KAMIJIMA Michihiro, HAMAJIMA Nobuyuki, ITO Yuki, SUZUKI Koji, INOUE Takashi, YAMAMOTO Kanami, TAKAGI Kenji, SAITO Isao, MIYAMOTO K, HASEGAWA Takaaki, KONDO Takaaki

Environ Res   Vol. 109 ( 2 ) page： 175-180   2009.2

Effects of short-term variation in body mass index on blood pressure in middle-aged Japanese male workers. Reviewed

KONDO Takaaki, KIMATA Akiko, YAMAMOTO Kanami, UEYAMA Sayoko, UEYAMA Jun, HORI Yoko

J Health Sci   Vol. 55 ( 1 ) page： 62-71   2009.2

Relationship between urinary pesticide metabolites and pest control operation among occupational pesticide sprayers Reviewed

KIMATA Akiko, KONDO Takaaki, UEYAMA Jun, YAMAMOTO Kanami, KAMIJIMA Michihiro, SUZUKI Koji, INOUE Takashi, ITO Yuki, HAMAJIMA Nobuyuki.

J Occup Health   Vol. 51 ( 1 ) page： 100-105   2009.1

Use of waist circumference and ultrasonographic assessment of abdominal fat distribution in predicting metabolic risk factors in healthy Japanese adults Reviewed

KONDO Takaaki, ABE Maimi, UEYAMA Jun, KIMATA Akiko, YAMAMOTO Kanami, HORI Yoko.

J Physiol Anthropo   Vol. 28 ( 1 ) page： 7-14   2009.1

Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells Reviewed

ARISAWA Sakiko, ISHIDA Kumiki, KAMEYAMA Natsumi, UEYAMA Jun, HATTORI Ai, TATSUMI Yasuaki, HAYASHI Hisao, YANO Motoyoshi, HAYASHI Kazuhiko, KATANO Yoshiaki, GOTO Hidemi, TAKAGI Kenji, WAKUSAWA Shinya

Biochem Pharmacol   Vol. 77 ( 5 ) page： 858-866   2009.1

Effect of the organophosphorus pesticide diazinon on glucose tolerance in type 2 diabetic rats Reviewed

UEYAMA Jun, KAMIJIMA Michihiro, ASAI Kazumi, MOCHIZUKI Aiko, WANG Dong, KONDO Takaaki, SUZUKI Takayuki, TAKAGI Kenji, TAKAGI Kenji, KANAZAWA Hiroaki, MIYAMOTO Ken-ichi, WAKUSAWA Shinya, HASEGAWA Takaaki.

Toxicol Lett   Vol. 182 ( 1-3 ) page： 42-47   2008.11

Role of plasma proteins in pharmacokinetics of micafungin, an antifungal antibiotic, in analbuminemic rats Reviewed

ABE Fumie, UEYAMA Jun, KAWASUMI Noriyo, NADAI Masayuki, HAYASHI Tamon, KATO Miki, OHNISHI Masafumi, SAITO Hiroko, TAKEYAMA Naoshi, HASEGAWA Takaaki.

Antimicrob Agents Chemother   Vol. 52 ( 9 ) page： 3454-3456   2008.9

Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats Reviewed

ABE Fumie, UEYAMA Jun, KIMATA Akiko, KATO Miki, Hayashi T, NADAI Masayuki, SAITO Hiroko, TAKEYAMA Naoshi, NOGUCHI Hiroshi, HASEGAWA Takaaki.

Life Sci   Vol. 83 ( 7-8 ) page： 229-235   2008.8

Effect of thalidomide on endotoxin-induced decreases in activity and expression of hepatic cytochrome P450 3A2 Reviewed

UEYAMA Jun, NADAI Masayuki, ZHAO Ying Lan, KANAZAWA Hiroaki, TAKAGI Kenji, KONDO Takaaki, TAKAGI Kenzo, WAKUSAWA Shinya, ABE Fumie, SAITO Hiroko, MIYAMOTO K, HASEGAWA Takaaki.

Biol Pharm Bull   Vol. 31 ( 8 ) page： 1596-1600   2008.8

Involvement of -pro-inflammatory mediators in endotoxin-induced overproduction of inducible nitric oxide synthase and decrease in expression of hepatic cytochrome P450 Reviewed

UEYAMA Jun, WAKUSAWA Shinya, FUKAYA Yukio, HASEGAWA Takaaki.

Bull Aichi Bunkyo Women's Coll   Vol. 29   page： 39-49   2008.3

Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer Reviewed

ZHANG Shu-Yun, UEYAMA Jun, ITO Yuki, YANAGIBA Yukie, OKAMURA Ai, KAMIJIMA Michihiro, NAKAJIMA Tamie.

Toxicology   Vol. 248 ( 2-3 ) page： 136-141   2008.3

Acute effect of exercise on blood pressure among fitness facility users, with special reference to influence of body mass index Reviewed

KONDO Takaaki, UEYAMA Jun, KIMATA Akiko, YAMAMOTO K, FUKAYA Yukio.

Bull Aichi Bunkyo Women's Coll   Vol. 29   page： 27-37   2008.3

Increase in P-glycoprotein accompanied by activation of protein kinase C alpha and NF-kappa B p65 in the livers of rats with streptozotocin-induced diabetes Reviewed

KAMEYAMA Natsumi, ARISAWA Sakiko, UEYAMA Jun, KAGOTA Satomi, SHINOZUKA Kazumasa, HATTORI Ai, TATSUMI Yasuaki, HAYASHI Hisao, TAKAGI Kenji, WAKUSAWA Shinya

Biochim Biophys Acta   Vol. 1782 ( 5 ) page： 355-360   2008.3

Association of serum NOx level with clustering of metabolic syndrome components in middle-aged and elderly general populations in Japan Reviewed

UEYAMA Jun, KONDO Takaaki, IMAI Ryota, KIMATA Akiko, YAMAMOTO Kanami, SUZUKI Koji, INOUE Takashi, ITO Yoshinori, MIYAMOTO Ken-ichi, HASEGAWA Takaaki, HAMAJIMA Nobuyuki.

Environ Health Prev Med   Vol. 13 ( 1 ) page： 36-42   2008.1

Association of glycemic profiles with whole blood polyamine among middle-aged Japanese men: colorimetric assay using oat and barley seedling polyamine oxidase Reviewed

KONDO Takaaki, YAMAMOTO Kanami, KIMATA Akiko, UEYAMA Jun, HORI Yoko, TAKAGI Kenji.

Environ Health Prev Med   Vol. 13 ( 1 ) page： 43-51   2008.1

Direct analysis of permethrins in human blood by SPE-GC/MS Reviewed

OGATA-KAWATA H, MATSUDA M, ONDA N, UEYAMA Jun, KAMIJIMA Michihiro, SHIBATA Eiji, OGAWA M, ENDO Y.

Chromatography   Vol. 28 ( 3 ) page： 119-124   2007.12

健常成人男性で体重が血圧に与える影響 －経年的測定データの多重レベル解析－ Reviewed

近藤高明, 上山純, 木全明子, 山本佳那実, 堀容子.

厚生の指標   Vol. 54 ( 13 ) page： 7-13   2007.11

Biological monitoring of pyrethroid exposure for pest control workers in Japan Reviewed

WANG Dong, KAMIJIMA Michihiro, IMAI Ryota, SUZUKI Takayuki, KAMEDA Yohei, ASAI Kazumi, OKAMURA Ai, NAITO Hisao, UEYAMA Jun, SAITO Isao, NAKAJIMA Tamie, GOTO Masahiro, SHIBATA Eiji, KONDO Takaaki, TAKAGI Kenji, TAKAGI Kenzo, WAKUSAWA Shinya.

J Occup Health   Vol. 49 ( 6 ) page： 509-514   2007.11

Lack of effect of aerobic physical exercise on endothelium-derived nitric oxide concentrations in healthy young subjects. Reviewed

YAMAMOTO Kanami, KONDO Takaaki, KIMATA Akiko, UEYAMA Jun, SHIROTORI Aya, OKADA Yoshiko, SAKUI Daisuke, NAKASHIMA Masahiro, YAMADA Sumio

Nagoya J Med Sci.   Vol. 69 ( 3-4 ) page： 167-172   2007.9

Permethrin may disrupt testosterone biosynthesis via mitochondrial membrane damage of Leydig cells in adult male mouse Reviewed

ZHANG Shu-Yun, ITO Yuki, YAMANOSHITA Osamu, YANAGIBA Yukie, KOBAYASHI Miya, Taya Kazuyoshi, LI ChunMei, OKAMURA Ai, Miyata Maiko, UEYAMA Jun, LEE Chul-Ho, KAMIJIMA Michihiro, NAKAJIMA Tamie.

Endocrinology   Vol. 148 ( 8 ) page： 3941-3949   2007.8

Association of a polymorphism in the ornithine decarboxylase gene with whole blood polyamine concentrations in a non-smoking healthy population Reviewed

KONDO Takaaki, HAMAJIMA Nobuyuki, NISHIO Kazuko, ISHIDA Yoshiko, IMAI Ryota, UEYAMA Jun, TORITA Shoko, KASAI Yurie, YAMAMOTO Ryoko, SUZUKI Koji, ITO Yoshinori.

J Health Sci   Vol. 53 ( 4 ) page： 406-412   2007.8

Toxicity of diazinon and its metabolites increases in diabetic rats Reviewed

UEYAMA Jun, WANG Dong, KONDO Takaaki, SAITO Isao, TAKAGI Kenji, TAKAGI Kenzo, KAMIJIMA Michihiro, NAKAJIMA Tamie, MIYAMOTO K, WAKUSAWA Shinya, HASEGAWA Takaaki.

Toxicol Lett   Vol. 170 ( 3 ) page： 229-237   2007.4

Lack of Effect of Aciclovir on Metabolism of Theophylline andExpression of Hepatic Cytochrome P450 1A2 in Rats Reviewed

NADAI Masayuki, KATO Miki, YASUI Kazumasa, KIMURA Masao, ZHAO Ying Lan, UEYAMA Jun, TSUNEKAWA Yoshimi, YOSHIZUMI Hideo, HASEGAWA Takaaki.

Biol Pharm Bull   Vol. 30 ( 3 ) page： 562-568   2007.3

Serial Variations in Serum Hepatic Profiles among Occupational Pesticide Sprayers: Multilevel Analyses of 14-Year Health Check-up Data Reviewed

KONDO Takaaki, UEYAMA Jun, FUKAYA Yukio, GOTO Masahiro.

Bull Aichi Bunkyo Women's Coll   Vol. 28   page： 1-7   2007.3

Involvement of nitric oxide (NO) in endotoxin-induced decrease in expression of hepatic cytochrome P450 Reviewed

UEYAMA Jun, KONDO Takaaki, FUKAYA Yukio, HASEGAWA Takaaki.

Bull Aichi Bunkyo Women's Coll   Vol. 28   page： 9-16   2007.3

8-Hydroxydeoxyguanosine levels in human leukocyte and urine according to exposure to organophosphorus pesticides and paraoxonase 1 genotype Reviewed

LEE Chul-Ho, KAMIJIMA Michihiro, KIM Heon, SHIBATA Eiji, UEYAMA Jun, SUZUKI Takayoshi, TAKAGI Kenji, SAITO Isao, GOTO Masahiro, HIBI Hattsuki, NAITO Hisao, NAKAJIMA Tamie.

Int Arch Occup Environ Health   Vol. 80 ( 3 ) page： 217-227   2007.1

Association of abdominal circumference with serum nitric oxide concentration in healthy population Reviewed

KONDO Takaaki, UEYAMA Jun, IMAI Ryota, SUZUKI Koji, ITO Yoshinori

Environ Health Prev Med   Vol. 11 ( 6 ) page： 321-325   2006.12

Protein kinase Cbeta isoform down-regulates the expression of MDR3 P-glycoprotein in human Chang liver cells Reviewed

SUZUKI Satoshi, HAYASHI Hisao, TAKAGI Kenji, KONDO Takaaki, TAKAGI Kenji, UEYAMA Jun, WAKUSAWA Shinya.

Biochim Biophys Acta   Vol. 1760 ( 10 ) page： 1552-1557   2006.10

健常成人集団での加齢と経年的血圧変動との関連性　－一般線形混合モデルの適用－ Reviewed

近藤高明、渡邊ゆかり、上山　純、堀　容子、八谷　寛、玉腰浩司、豊嶋英明.

日循予防誌   Vol. 41 ( 2 ) page： 55-61   2006.10

人工重力とエルゴメータ運動の併用により、無為臥床により惹起される心萎縮は防止可能である Reviewed

岩瀬三紀, 武市康志, 石木良治, 稲垣春夫, 岩瀬 敏, 井澤英夫, 永田浩三, 上山　純, 加藤洋介, 野田明子, 古池保雄, 横田充弘.

心臓   Vol. 38   page： 20-23   2006.4

Simultaneous determination of urinary dialkyl phosphate metabolites of organophosphorus pesticides using gas chromatography-mass spectrometry Reviewed

UEYAMA Jun, SAITO Isao, KAMIJIMA Michihiro, NAKAJIMA Tamie, GOTOH Masahiro, SUZUKI Takayuki, SHIBATA Eiji, KONDO Takaaki, TAKAGI Kenji, MIYAMOTO Ken-ichi, TAKAMATSU Junki, HASEGAWA Takaaki, TAKAGI Kenzo

J Chromatogr B   Vol. 832   page： 58-66   2006.2

A comprehensive evaluation of the testicular toxicity of dichlorvos in Wistar rats Reviewed

OKAMURA Ai, KAMIJIMA Michihiro, SHIBATA Eiji, OHTANI Katsumi, TAKAGI Kenji, UEYAMA Jun, WATANABE Yukari, OMURA Minoru, WANG Hailan, ICHIHARA Gaku, KONDO Takaaki, NAKAJIMA Tamie.

Toxicology   Vol. 213   page： 129-137   2005.9

生活習慣病患者における血漿NOの検討 Reviewed

宮田聖子, 野田明子, 安藤晃禎, 吉村敦子, 上山　純, 北市清幸, 黒木祥子, 助川真代, 古池保雄, 横田充弘.

日本臨床生理学会雑誌   Vol. 35 ( 1 ) page： 39-43   2005.4

Endotoxin from various gram-negative bacteria has differential effects on function of hepatic cytochrome P450 and drug transporters Reviewed

UEYAMA Jun, NADAI Masayuki, KANAZAWA Hiroaki, IWASE Mitsunori, NAKAYAMA Hironao, HASHIMOTO Katsunori, YOKOI T, BABA Kenji, TAKAGI Kenji, TAKAGI Kenzo, HASEGAWA Takaaki.

Eur J Pharmacol   Vol. 510   page： 127-134   2005.3

Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin Reviewed

MIYOSHI Mika, NADAI Masayuki, NITTA Atsumi, UEYAMA Jun, SHIMIZU Akemi, TAKAGI Kenji, NABESHIMA Toshitaka, TAKAGI Kenji, SAITO Kuniaki, HASEGAWA Takaaki.

Eur J Pharmacol   Vol. 507   page： 229-237   2005.1

Possible involvement of P-glycoprotein in renal excretion of pazufloxacin in rats Reviewed

SHIMIZU Akemi, MIYOSHI Mika, SUGIE Masami, UEYAMA Jun, YAMAGUCHI Takuji, SASAKI Toshinobu, TAKAGI Kenji, JIN Mingji, MIYAMOTO Ken-ichi, TSUJI Akira, HASEGAWA Takaaki.

Eur J Pharmacol   Vol. 501   page： 151-159   2004.10

Effect of pioglitazone on endotoxin-induced decreases in hepatic drug-metabolizing enzyme activity and expression of CYP3A2 and CYP2C11 Reviewed

UEYAMA Jun, KITAICHI Kiyoyuki, NADAI Masayuki, IWASE Mitsunori, TOMYO Nao, KANAZAWA Hiroaki, SUZUKI Ryojiro, TAKAGI Kenji, TAKAGI Kenzo, HASEGAWA Takaaki.

Eur J Pharmacol   Vol. 498   page： 257-265   2004.9

Down-regulation of cytochrome P450 proteins and its activities by Shiga-like toxin II from Escherichia coli O157:H7 Reviewed

KITAICHI Kiyoyuki, NAKAYAMA Hironao, UEYAMA Jun, NADAI Masayuki, BABA Kenji, TAKAGI Kenji, TAKAGI Kenzo, OHTA Michio, HASEGAWA Takaaki

Biochem Pharmacol   Vol. 67   page： 1427-1435   2004.4

Application of ultrafiltration method to measurement of catecholamines in plasma of human and rodents by high-performance liquid chromatography Reviewed

UEYAMA Jun, KITAICHI Kiyoyuki, IWASE Mitsunori, TAKAGI Kenji, TAKAGI Kenzo, HASEGAWA Takaaki

J Chromatogr B   Vol. 798   page： 35-41   2003.12

Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats Reviewed

KITAICHI Kiyoyukiiyoyuki, MORISHITA Yuki, DOI Yuko, UEYAMA Jun, MATSUSHIMA Miyoko, ZHAO Ying Lan, TAKAGI Kenji, HASEGAWA Takaaki

Eur J Pharmacol   Vol. 464   page： 39-48   2003.3

分子予防環境医学・Ⅲ-14 農薬類

上島通浩、伊藤由起、上山純（ Role： Joint author）

本の泉社  2010.12  （ ISBN:4780706017 ）

広範囲 血液・尿化学検査，免疫学的検査（第7版）2-その数値をどう読むか2010年増刊号

上島通浩、上山純、高木健次、柴田英治（ Role： Joint author）

日本臨床  2010.1 

覚醒剤の生体内運命.「覚せい剤依存と麻薬依存」 佐藤光源、櫻井映子　編

北市清幸、森下友貴、土井悠子、上山純、松島充代子、巽康彰、高木健次、柴田英治、高木健三、長谷川高明（ Role： Joint author）

東北大学出版会  2004.4 

LC-MS/MS を用いた便中ビタミンB 群測定法の開発

髙目 楓華，竹村 呼，野崎 七美，平山 正昭，上山 純

第48 回日本医用マススペクトル学会年会  2023.9.8 

固相ミニカートリッジSmart-SPE を前処理法に用いたLC-MS/MS による血中薬物同時定量法

石原 みゆ，本多 祥子，梶本 葵里，上出 真琴，寿台 直人，上山 純，鈴木 隆佳

第48 回日本医用マススペクトル学会年会  2023.9.8 

Redox state of human serum albumin predicts 1-year prognosis in patients with heart failure: a single-center prospective cohort study International conference

Taiki Nishikawa, Jun Ueyama, Shinjiro Miyata ,Shinya Shimizu, Yoshihisa Shibata, Sumio Yamada

European Society of Cardiology congress 2023  2023.8.26 

Human biomonitoringによる曝露評価-バイオモニタリングにおける化学分析- Invited

上山純

第2回環境化学物質3学会合同大会  2023.6.2 

生体試料分析の仕方と読み方と頼み方 －衛生学の領域から― Invited

上山純

大学院保健学研究科 第92回保健学セミナー  2023.5.24  藤田医科大学

職業的化学物質ばく露評価に向けた尿中半揮発性物質の網羅的測定法の開発

上山純、北原悠吾、棚橋祐斗、竹内靖人、佐久井徳広、斎藤勲

第93回日本衛生学会学術総会  2023.3.4 

Association of redox state of human serum albumin with severity in patients with heart failure: a cross-sectional study International conference

Taiki Nishikawa; Shinya Shimizu; Haruo Kamiya; Jun Ueyama, Sumio Yamada

9th Asian Preventive Cardiology & Cardiac Rehabilitation Conference  2022.11.26 

化学物質曝露モニタリング研究を支えるバイオマーカーデータベース構築

上山純、北原悠吾、竹内靖人、棚橋祐斗、佐久井徳広、斎藤勲

第４９回生物学的モニタリング・バイオマーカー研究会  2022.10.22  日本産業衛生学会

職業的な化学物質ばく露評価に向けた尿中半揮発性物質の網羅的測定法の開発

北原悠吾、棚橋祐斗、竹内靖人、佐久井徳広、斎藤勲、上山純

第４９回生物学的モニタリング・バイオマーカー研究会  2022.10.22  日本産業衛生学会

A preliminary study on the effect of pesticide intake on gut microbiota and metabolites in middle-aged and elderly Japanese International conference

Mai Hayashi, Masaaki Hirayama, Nanami Nishihara, Yugo Kitahara, Takaaki Kondo, Mikako Ito , Kinji Ohno, Jun Ueyama

International Society of Exposure Science 2022 Annual Meeting  2022.9.27 

Simultaneous analysis of urinary insect repellents and its metabolites using high-performance liquid chromatography-tandem mass spectrometry International conference

Nanami Nishihara, Tomohiko Isobe, Mai Takagi, Isao Saito, Shoji Nakayama, Miyuki Iwai-Shimada, Tatsuya Kunisue, Tomoko Oguri, Jun Ueyama

International Society of Exposure Science 2022 Annual Meeting  2022.9.27 

Temporal trend and cross-sectional characterization of urinary concentrations of glyphosate in Japanese children from 2006 to 2015 International conference

International Society of Exposure Science 2022 Annual Meeting  2022.9.28 

人囮法によるヒトスジシマカ雌成虫の捕獲数についての予測モデルの開発

渡邉　悟 、北原悠吾、西原奈波、中根邦彦、近藤高明、上山　純

第68回東海公衆衛生学会学術大会  2022.7.2 

化学物質の体内動態を把握するためのパーソナルケア製品使用と食事をコントロールした介入試験の提案

磯部友彦、中山祥嗣、岩井美幸、高木麻衣、上山 純、小栗朋子 、篠原直秀、国末達也、仲山 慶、田上瑠美

環境化学物質3学会合同大会  2022.6.14 

Validation and Application of Analytical Method of Urinary Repellents

Jun Ueyama1, Nanami Nishihara, Mai Takagi, Miyuki Iwai, Yugo Kitahara, Tomohiko Isobe

2022.6.14 

Suspected phenolic endocrine-disrupting compounds in human urine and exposure media: estimation of exposure levels and excretion rates

2022.6.14 

人囮法によるヒトスジシマカ雌成虫の捕獲数を予測する モデルの開発

渡邉 悟、北原 悠吾、西原 奈波、中根 邦彦、 近藤 高明、上山 純

第92回日本衛生学会学術総会  2022.3.22  日本衛生学会

尿中忌避剤および代謝物同時測定法の妥当性評価とそ の応用

西原 奈波、藪本 奈那、白石 愛深、髙木 麻衣、 磯部 友彦、上山 純

第92回日本衛生学会学術総会  2022.3.22  日本衛生学会

尿中有機リン系殺虫剤代謝物濃度と便中短鎖脂肪酸濃 度の関係

林 舞衣、平山 正昭、角田 菜緒、北原 悠吾、斎藤 勲、 伊藤 美佳子、大野 欽司、上山 純

第92回日本衛生学会学術総会  2022.3.22  日本衛生学会

生体試料を用いた化学物質ばく露評価研究 Invited

上山純

LaMer公開シンポジウム  2022.1.27  愛媛大学

見る聞く触る　現場からまなぶ自動化の実際 Invited

Laboratory Automation Developers Conference 2021  2021.12.17  Laboratory Automation Supplier's Association

昆虫食におけるヒ素・重金属のリスク評価

北原悠吾, 野村洸司, 上田琢也, 西原奈波, 斎藤勲, 上山純

日本食品衛生学会第117回学術講演会  2021.10.26 

Characteristics of glyphosate exposure level in Japanese children by biological monitoring method using LC-MS/MS

2021.9.17 

ヒト尿中およびパーソナルケア製品中の フェノール性内分泌かく乱化学物質：濃度変動と曝露評価

大浦 奏、田上 瑠美、上山 純、小栗 朋子、磯部 友彦、国末 達也

第23回環境ホルモン学会研究会  2021.9.12 

尿サンプルを対象とした自動サンプル 前処理システムの導入の理想と現実 Invited

上山純

Laboratory Automation月例勉強会  2021.8.20  Laboratory Automation Supplier's Association

web調査を利用した蚊の穿刺被害把握の試み

上山純、中根邦彦、渡邉悟、中根敏裕、青山政美、服部悟、西原奈波、北原悠吾、近藤高明、斎藤勲

第67回東海公衆衛生学会学術大会  2021.7.3  東海公衆衛生学会

日常的に使用する殺虫剤や忌避剤のばく露を把握する Invited

上山純

第91回日本衛生学会市民公開講座  2021.3.6  日本衛生学会

1.5歳児を対象としたピレスロイド系殺虫剤代謝物の一斉定量分析

上山純、伊藤由起、大矢奈穂子、浜田梨沙、上田裕子、小田昌也、加藤沙耶香、佐藤博貴、榎原毅、上島通浩

第91回　日本衛生学会学術総会   2021.3.7 

尿中新規忌避剤ピカリジンの高感度測定法の検討

西原奈波、高須未波、野村洸司、斎藤勲、上山純

第91回　日本衛生学会学術総会   2021.3.7 

国内衛生行政による蚊のサーベイランス実態調査および成虫発生予測の試み

渡邉　悟、余合　結、中根邦彦、上山　純

第91回　日本衛生学会学術総会   2021.3.7 

尿中曝露マーカー測定におけるクレアチニン調整希釈法の有用性の検討

北原 悠吾、野村洸司、浜田梨沙、藤原 有花、斎藤勲、上山純

第91回　日本衛生学会学術総会   2021.3.7 

LC-MS/MSを用いた尿中グリホサート分析法の開発 Invited

上山純

アジレント・テクノロジー　サンプル前処理ウェビナー2020特別講演  2020.10.16  アジレントテクノロジー株式会社

CHARACTERISTICS OF URINARY METABOLITES AS A BIOMARKER OF HOUSEHOLD PYRETHROID INSECTICIDES International conference

R. Hamada, K. Wada, M. Oda, Y. Ueda, I. Saito, M. Kamijima, K. Nakane, T. Kondo, C. Nagata, J. Ueyama

11th International Symposium on Biological Monitoring in Occupational and Environmental Health  2019.8.29 

害虫忌避剤ディートの尿中代謝物高感度測定法の開発

上山純, 上瀬佳菜,浜田梨沙,中根邦彦,近藤高明,佐藤光夫,斎藤勲

第89回　日本衛生学会学術総会 

1才半児におけるジノテフラン曝露量と生活環境および食意識との関連

大矢奈穂子,伊藤由起,上山純,加藤沙耶香,松木太郎,佐藤博貴,齋藤伸治,杉浦真弓,榎原毅,上島通浩

第89回　日本衛生学会学術総会 

便中短鎖脂肪酸分析における測定前変動要因の解明と便凍結乾燥処理の有用性の検証

小田真也, 杉立久仁代, 佐久井徳広, 瀧本圭一, 伊藤美佳子, 平山正昭, 大野欽司, 上山純

第８８回　日本衛生学会学術総会 

日本の幼児における有機リン系殺虫剤曝露と生活環境との関連

伊藤由起、大矢奈穂子、日置啓介、上山　純、青井亜里沙、小栗朋子、加藤沙耶香、齋藤伸治、榎原　毅、上島通浩

第８８回　日本衛生学会学術総会 

使用済み紙おむつを用いた１歳半児における尿中ネオニコチノイド系殺虫剤の測定

大矢奈穂子、伊藤由起、上山　純、青井亜里沙、小栗朋子、加藤沙耶香、榎原　毅、齋藤伸治、上島通浩

第８８回　日本衛生学会学術総会 

新規ピレスロイド系殺虫剤代謝物の3歳児尿中濃度に関する基礎的調査

上田裕子、市川みずき、斎藤勲、大坂彩、野村洸司、近藤高明、中根邦彦, 上山純

第８８回　日本衛生学会学術総会 

バイオモニタリング手法を用いた日本人小児ピレスロイド系殺虫剤曝露レベルの国際比較

上山　純、上田裕子、伊藤由起、榎原　毅、大矢奈穂子、加藤沙耶香、小栗朋子、庄司直人、齋藤伸治、上島通浩

第８８回　日本衛生学会学術総会 

日本人妊婦の尿中ネオニコチノイド系農薬濃度

飴田　玲伽、青井　亜里沙、上山　純、西浜　柚季子、 吉永　淳、久田 文、下平 和久、加藤 進昌

環境ホルモン学会　第19回研究発表会  

ラットを用いた殺虫剤アセタミプリドおよび代謝物の血中および尿中動態

生田勇太郎、上山純、青井亜里沙、近藤高明、涌澤伸哉、伊藤由起、上島通浩、斎藤勲

第８６回日本衛生学会学術総会 

尿中有機リン系殺虫剤代謝物測定の個人間変動と施設間差についての検討

伊藤由起、上山純、中山祥嗣、磯部友彦、佐藤博貴、大矢奈穂子、仲井邦彦、上島通浩

第８６回日本衛生学会学術総会 

使用済みオムツを用いた１歳半児における尿中有機リン系殺虫剤曝露量の測定

大矢奈穂子、伊藤由起、日置啓介、浅井祐哉、青井愛里沙、上山純、小栗朋子、加藤沙耶香、榎原毅、上島通浩

第８６回日本衛生学会学術総会 

Measurement of concentrations of organophosphate insecticide metabolites in urine extracted from used diapers in 1.5-year-old children International conference

Naoko Oya, Yuki Ito, Keisuke Hioki, Yuya Asai, Arisa Aoi, Yuka Sugiura, Jun Ueyama, Tomoko Oguri, Sayaka Kato, Takeshi Ebara, Michihiro Kamijima

2nd international conference on human biomonitoring 

Concentration s of urinary pyrethroid metabolites in Japanese women between 1994-2011 International conference

Jun Ueyama, Koouji H Harada, Akio Koizumi, Yutaro Ikuta, Takaaki Kondo, Isao Saito, Michihiro Kamijima

2nd international conference on human biomonitoring 

Interlaboratory and intraindividual variability analysis in measurements of urinary metabolites of organophosphorus insecticides International conference

Yuki Ito, Jun Ueyama,Shoji Nakayama, Tomohiko Isobe, Hirotaka Sato, Naoko Oya, Koichi Yoshimasu, Kanami Tsuno, Nozomi Tatsuta, Kunihiko Nakai, Michihiro Kamijima

2nd international conference on human biomonitoring 

バイオモニタリング手法を用いたネオニコチノイド系殺虫剤の曝露評価

上山純,末永隆次郎,永美大志,夏川周介,柴田英治,近藤高明,上島通浩,斎藤勲

平成27年度日本産業衛生学会　東海地方会 

有機リン系殺虫剤分解酵素活性と尿中代謝物の関連

佐藤博貴,伊藤由紀,上山純,加納裕也,荒川朋弥,五藤雅博,近藤高明,杉浦友香,斎藤勲,柴田英治,上島通浩

平成27年度日本産業衛生学会　東海地方会 

使用済みオムツを利用した尿中代謝物一斉分析法の開発 International conference

杉浦友香、上山純、上田裕子、伊藤由起、涌澤伸哉、上島通浩

第43回産業中毒・生物学的モニタリング研究会 

尿中有機リン系殺虫剤代謝物測定の施設間、個人間変動についての検討

伊藤由起、上山 純、中山祥嗣、磯部友彦、佐藤博貴、仲井邦彦、上島通浩

第43回産業中毒・生物学的モニタリング研究会 

殺虫剤類の個人曝露量測定と健康リスク評価

上島通浩、伊藤由起、上山純

第42回 日本毒性学会学術年会　シンポジウム 

使い捨てオムツを用いた尿中低分子代謝物類の網羅的分析

杉浦友香、上山純、上田裕子、涌澤伸哉、上島通浩

第85回日本衛生学会学術総会 

日本人における尿中殺虫剤曝露指標濃度の過去20年間の経年推移

上山純、原田浩二、杉浦友香、大坂彩、小泉昭夫、上島通浩

第85回日本衛生学会学術総会 

3歳児における尿中殺虫剤曝露指標の相関関係

上山純、大坂彩、野村洸司、斎藤勲、近藤高明、 黄木弘子、高石亜有子、伊藤由起、上島通浩

第85回日本衛生学会学術総会 

３歳児を対象とした有機リン系・ピレスロイド系・ネオニコチノイド系殺虫剤の 尿中曝露指標一斉分析

大坂彩, 上山純, 野村洸司, 斎藤勲, 近藤高明, 黄木弘子, 高石亜有子, 伊藤由起, 上島通浩

第42回産業中毒・生物学的モニタリング研究会 

日本人における尿中ネオニコチノイド系 殺虫剤とその代謝物の濃度分布

上山純,　野村洸司, 斎藤勲, 近藤高明, 岩田豊人, 村田勝敬, 涌澤伸哉, 上島通浩

第41回日本毒性学会学術年会 

日本人小児を対象とした尿中ピレスロイド系殺虫剤代謝物の高感度分析

大坂彩, 上山純, 近藤高明, 野村洸司, 斎藤勲, 犬塚君雄, 黄木弘子, 高石亜有子, 上島通浩

第84回日本衛生学会学術総会 

LC-MS/MSによる尿中のネオニコチノイド系殺虫剤同時定量分析法の開発

上山純, 野村洸司, 斎藤勲, 近藤高明, 伊藤由起, 上島通浩

第84回に本衛生学会学術総会 

Concentration distribution of urinary pyrethroid insecticide metabolites in Japanese workers International conference

Jun Ueyama, Hiroshi Nomura, Isao Saito, Takaaki Kondo, Yuka Sugiura, Katsuyuki Murata, Toyoto Iwata, Masahiro Gotoh, Shinya Wakusawa, Michihiro Kamijima

International Society of Exposure Science 2013 Annual Meeting  2013.8.20 

Quantitation of neonicotinoid metabolites in human urine using gas chromatography-mass spectrometry International conference

Hiroshi Nomura, Jun Ueyama, Takaaki Kondo, Isao Saito, Katsuyuki Murata, Toyoto Iwata, Shinya Wakusawa, Michihiro Kamijima

International Society of Exposure Science 2013 Annual Meeting  2013.8.20 

Simultaneous determination of urinary pyrethroid insecticide metabolites in disposable diaper samples

Jun Ueyama, Shun Saito, Takaaki Kondo, Isao Saito, Masahiro Gotoh, Kunihiko Nakai, Michihiro Kamijima

7th International Conference on the Science of Exposure Assessment  2012.7.3 

パラオキソナーゼ1遺伝子多型と腎機能評価指標との関連－予備的解析-

上山純、本郷あやの、近藤高明、森田えみ、川合紗世、岡田理恵子、伊藤宜則、内藤真理子、若井健志、浜島信之

第82回日本衛生学会学術総会 

血清脂肪酸（ＦＡ）とＦＡ摂取量およびメタボリックシンドローム（ＭｅｔＳ）リスク

田中哲也、近藤高明、喜田優人、上山純、鈴木康司、井上孝、伊藤宜則、若井健志、浜島信之

第82回日本衛生学会学術総会 

殺虫剤撒布職域従事者における尿中クレアチニン分析値の検討

大坂彩、上山純、近藤高明、五藤雅博、柴田英治、涌澤伸哉、斎藤勲、上島通浩

第82回日本衛生学会学術総会 

Concentration of urinary organophosphorus insecticide metabolites in Japanese workers International conference

Jun Ueyama, Isao Saito, Takaaki Kondo, Taki Tomoko, Akiko Kimata, Shun Saito, Katsuyuki Murata, Toyoto Iwata, Masahiro Goto, Eiji Shibata, Shinya Wakusawa, Michihiro Kamijima

21st Annual Meeting of The International Society of Exposure Science 

使い捨て紙オムツを利用した尿中殺虫剤代謝物測定法の検討

齋藤峻、上山純、斎藤勲、近藤高明、涌澤伸哉、 五藤雅博、柴田英治、近並由佳、仲井邦彦、上島通浩

第 39 回 産業中毒・生物学的モニタリング研究会 

一般生活集団における血清中脂肪酸とメタボリックシンドローム診断項目との関連

田中哲也, 近藤高明, 喜田優人, 上山純, 浜島信之, 鈴木康司, 井上孝, 倉岡光穂, 王音晴, 蓮井恵子

第81回日本衛生学会学術総会 

問診票による身体活動量推定量と血圧や血清生化学検査値との関連

近藤高明, 加藤千秋, 喜田優人, 田中哲也, 上山純

第81回日本衛生学会学術総会 

２４時間尿中クレアチニン排泄量予測値を用いた２４時間尿中殺虫剤代謝物排泄量の推定

齋藤峻, 上山純, 近藤高明, 田中哲也, 廣澤菜緒子, 北洞久美子, 高木健次, 上島通浩, 涌澤伸哉

第81回日本衛生学会学術総会 

異なる前処理による尿中ピレスロイド代謝産物測定値の変動

登島弘基, 吉永淳, 白石寛明, 伊藤由起, 上島通浩, 上山純

第81回日本衛生学会学術総会 

殺虫剤曝露指標の実践的応用を目指した基礎的研究

上山純, 近藤高明, 斎藤勲, 五藤雅博, 長谷川高明, 上島通浩

第81回日本衛生学会学術総会 

日本人の一般健常集団における種々の疾患歴とH.pylori感染との関連

喜田優人, 近藤高明, 上山純,田中哲也, 川合紗世, 森田えみ, 伊藤宜則, 内藤真理子, 若井建志, 浜島信之

第81回日本衛生学会学術総会 

ペルメトリン由来3-フェノキシ安息香酸の尿中排泄量に対する有機リン系殺虫剤の影響

藤中沙奈恵, 上山純, 廣澤奈緒子, 近藤高明, 上島通浩, 高木健次, 平手彩夏, 長谷川高明, 涌澤伸哉

第 38 回有機溶剤中毒研究会・第 43 回生物学的モニタリング・バイオマーカー研究会合同研究会  

非喫煙成人女性での尿中コチニン値と受動喫煙との関連

喜田優人, 近藤高明, 田中哲也, 中川優子, 木下香織, 鈴木麻予, 服部由花, 一ノ谷英憲, 木全明子, 上山純, 森田えみ, 田村高志, 栗木砂家加, 冨田耕太郎, 岡田理恵子, 川合紗世, 菱田朝陽, 内藤真理子, 若井建志, 浜島信之

第５６回東海公衆衛生学会学術大会 

健常成人集団での血清carotenoid値とmetabolic syndrome診断項目集積数との関連

田中哲也, 近藤高明, 田優人, 一ノ谷英憲,　山本佳那実, 鈴木麻予, 服部由花, 木全明子, 上山純

第５６回東海公衆衛生学会学術大会 

健常成人集団での血清carotenoid値と高密度との関連

近藤高明, 一ノ谷秀憲, 山本佳那実, 木全明子, 鈴木麻予, 服部由花, 木下香織, 中川優子, 上山純

第80回日本衛生学会学術総会 

ピレスロイド系殺虫剤代謝に関与するUDP-グルクロン酸転移酵素分子種の同定

齋藤峻, 上山純, 廣澤奈緒子, 望月愛子, 木全明子, 高木健次, 涌澤伸哉

第80回日本衛生学会学術総会 

使い捨て紙おむつを利用した尿中殺虫剤代謝物測定の試み

上山純, 伊藤牧, 齋藤勲, 高木健次, 近藤高明, 涌澤伸哉, 仲井邦彦, 佐藤洋, 上島通浩

第80回日本衛生学会学術総会 

一般生活者集団および殺虫剤散布職域集団の尿中有機リン系殺虫剤代謝物量

廣澤奈緒子, 上山純, 上島通浩, 木全明子, 岡村愛, 那須民江, 柴田英治, 五藤雅博、深谷幸生, 近藤高明, 高木健次, 涌沢伸哉

第３６回日本トキシコロジー学会学術年会 

日本人中高齢者における尿中ピレスロイド系殺虫剤代謝物および血中酸化ストレス指標との関連性

上山純, 木全明子, 上島通浩, 濱島信之, 鈴木康司, 井上孝, 伊藤宜則, 宮本謙一, 長谷川高明 ,高木健次, 涌沢伸哉, 近藤高明

第７９回日本衛生学会学術総会 

害虫防除作業者集団におけるフェニトロチオン散布とその尿中代謝物量との関連

岡村愛, 上島道浩, 上山純、 高木健次, 柴田英治, 内藤久雄、五藤雅博, 斉藤勲、那須民江.

第７９回日本衛生学会学術総会 

健常成人集団における血清8-iso-PGF2αと骨密度との関連

近藤高明、上山純、木全明子、山本佳那美、鈴木康司、井上孝、伊藤宣則、浜島信之

第７９回日本衛生学会学術総会 

ピレスロイド系殺虫剤代謝産物の体内動態における性差

"廣澤奈緒子1) , 上山純1,2) , 望月愛子1) , 木全明子1) , 高木健次1) , 近藤高明1) , 高木健三1) , 涌澤伸哉1) , 長谷川高明3)"

第７９回日本衛生学会学術総会 

Testicular toxicity in mice after combined exposure to pyrethroid and organophosphorus insecticides

Patterns of beta-glucuronidase in pesticide self- poisoning. International conference

7th Asia Pacific Association of Medical Toxicolog 

ダイアジノンとcis-ペルメトリンの混合曝露によるマウス精巣への影響

王棟、上島道浩、岡村愛、伊藤由起、柳場由絵、上山純、那須民江

平成２０年日本産業衛生学会東海地方学会 

一般生活集団における合成ピレスロイド系化合物の尿中代謝物濃度

上山純、木全明子、上島通浩、高木健次、涌く澤伸哉、高木健三、斎藤勲、宮本謙一、長谷川高明

第35回日本トキシコロジー学会学術年会 

男性健常成人集団における血中polyamine値の分布とmetabolic risk factorとの関連性

山本佳那美、近藤高明、木全明子、上山純、高木健次

第78回日本衛生学会総会 

合成ピレスロイド系殺虫剤ペルメトリン（trans;cis体）のマウス生殖毒性に関する研究

張淑芸、伊藤由起、柳場由絵、上山純、岡村愛、上島道浩、那須民江

第78回日本衛生学会総会 

ガスクロマトグラフ質量分析計によるフェニトロチオンの特異的尿中代謝産物3-メチル-4-ニトロフェノールの高感度測定法の開発

岡村愛、上島道浩、斉藤勲、市原学、伊藤由起、五藤雅博、柴田英治、髙木健次、近藤高明、上山純、那須民江

第78回日本衛生学会総会 

健常成人集団でのCETP TaqIB遺伝子多型と血管内皮由来NO濃度との関連性

近藤高明、上山純、吉武順子、木全明子、山本佳那美、鈴木康司、井上孝、伊藤宣則、浜島信之

第78回日本衛生学会総会 

男性健常成人集団における血中polyamine値の分布とmetabolic risk factorとの関連性

木全明子、上山純、近藤高明、山本佳那美、上島通浩、柴田英治、後藤雅博、深谷幸生、高木健次、那須民江、斉藤勲

第78回日本衛生学会総会 

有機リン系殺虫剤ダイアジノンが及ぼす２型糖尿病モデルラットの耐糖能への影響

浅井佳寿美、上山純、望月愛子、三河由佳、王棟、上島道浩、近藤高明、長谷川高明、高木健次、高木健三、涌澤伸哉

日本薬学会第１28年会 

ラットにおけるミカファンギンの胆汁排泄におけるMrp2およびP糖タンパク質の関与

安部文江、上山純、加藤美樹、灘井雅行、川澄紀代、木村匡男、斉藤寛子、武山直志、野口宏、長谷川高明

日本薬学会第１28年会 

生活習慣病モデルラットSHR/NDmcr-cpおよびSHRSP.ZFの肝臓における薬物トランスポーターの発現解析

有沢早葵子、亀山なつみ、佐野雅幸、石田空美季、上山純、篠塚和正、涌澤伸哉

日本薬学会第１28年会 

HepG2細胞におけるdoxorubicinのP-glycoprotein発現誘導に与えるepigallocatechin gallateの影響

石田空美季、佐野雅幸、亀山なつみ、有沢早葵子、上山純、高木健次、涌澤伸哉

日本薬学会第１28年会 

ウェスタンブロット法の内部標準物質に及ぼすエンドトキシンの影響

望月愛子、上山純、浅井佳寿美、王棟、安部文江、長谷川高明、近藤高明、高木健三、高木健次、涌澤伸哉

日本薬学会第１28年会 

職業的有機リン系殺虫剤曝露が及ぼす血漿中βグルクロニダーゼ活性値への影響

上山純、上島通浩、小笠原将人、木全明子、近藤高明、高木健三、宮本謙一、長谷川高明、佐藤哲男、斉藤勲、高木健次、涌沢伸哉

日本薬学会第１28年会 

streptozotocin誘発糖尿病ラットでのP糖タンパク誘導に伴うPKCαおよびNF-κBの発現変化

亀山なつみ、有沢早葵子、佐野雅幸、石田空美季、上山純、高木健次、涌澤伸哉

日本薬学会第１28年会 

Toxicity of diazinon and its metabolites increases in diabetic rats International conference

The seventh international symposium on biological monitoring in occupational & environmental health 

Biological monitoring of exposure to organophosphorus and pyrethroid insecticides in Japan - from the viewpoint of testicular toxicity assessment- International conference

The seventh international symposium on biological monitoring in occupational & environmental health 

Decrease in rat sperm motility is associated with cholinesterase activity inhibition by dichlorvos and diazinon treatment. International conference

11th IUPAC International Congress of Pesticide Chemistry. 

Permethrin may disrupt testosterone production in male mice. International conference

11th IUPAC International Congress of Pesticide Chemistry. 

Biological monitoring of pyrethroid exposure for pest control workers. International conference

11th IUPAC International Congress of Pesticide Chemistry. 

Effect of pioglitazone on endotoxin-induced decreases in hepatic drug-metabolizing enzyme activity and expression of CYP3A2 and CYP2C11. International conference

The 8th Conference of the International Endotoxin Society 

The lack of involvement of TNF-a, IL-1 and PAF in endotoxin-induced decrease in hepatic drug-metabolizing enzyme activity. International conference

The 18th International Congress of Clinical Chemistry and Laboratory Medicine 

Methamphetamine sensitization and pharmacokinetics. International conference

XII World Congress of Psychiatry 

Pharmacokinetic changes of methamphetamine and their mechanisms in rats having behavioral sensitization to methamphetamine. International conference

23rd Congress of Collegium Internationale Neuro-Psychopharmacologicum 

Altered disposition of methamphetamine in rats repeatedly treated with methamphetamine: the possible involvement of organic cation transporters. International conference

31th Annual Meeting Society for Neuroscience 

Repeated administration of methamphetamine alters pharmacokinetic parameters of methamphetamine in rats: the possible involvement of organic cation transporters. International conference

Congress of Collegium Internationale Neuro-Psychopharmacologicum, Regional meeting, 

低用量殺虫剤曝露の代謝物プロファイリング：エクスポソーム導入へのマイルストーン

Grant number：16H05259  2016.4 - 2019.3

科学研究費補助金  基盤研究(B)

上島通浩

尿中化学物質の網羅的分析による農薬類曝露マーカーの探索と分析法の開発

Grant number：26460799   2014.4 - 2017.3

科学研究費補助金  基盤研究(C)

胎児期の非蓄積性殺虫剤曝露の解明と出生児の成長・発達への影響に関するコホート研究

Grant number：25293151   2013.4 - 2016.3

科学研究費補助金  基盤研究(B)

上島通浩

殺虫剤の生体影響リスク評価へのメタボノミクスの導入

Grant number：20310035  2009.4 - 2011.3

科学研究費補助金  基盤研究（Ｂ）

上島通浩

殺虫剤曝露指標の実践的応用を目指した基礎的研究

Grant number：21790551   2009.4

科学研究費補助金  若手研究（Ｂ），課題番号：21790551

上山純

健常成人集団で腹部脂肪蓄積が血管内皮機能に及ぼす影響の分析化学的・生理学的評価

Grant number：19590626   2008.4 - 2010.3

科学研究費補助金  基盤研究（Ｃ）

近藤高明

一般集団での殺虫剤曝露が健康へ及ぼす影響に関する実験的・疫学的評価

Grant number：19790404   2007.4 - 2008.3

科学研究費補助金  若手研究（Ｂ）

上山　純

一般生活集団における殺虫剤曝露状況および疾患罹患時の体内動態の解明に関する研究

Grant number：17790364   2005.4 - 2007.3

科学研究費補助金  若手研究（Ｂ）

上山　純