Updated on 2021/04/28

写真a

 
ZINCHENKO, Anatoly
 
Organization
Graduate School of Environmental Studies Department of Environmental Engineering and Architecture Functional Materials and Environment Associate professor
Title
Associate professor
Contact information
メールアドレス

Degree 2

  1. Doctor (Engineering) ( 2004.3   Nagoya University ) 

  2. Master (Chemistry) ( 2000.6   Moscow State University, Chemistry Department ) 

Research Interests 3

  1. Polymers

  2. Nanomaterials

  3. DNA

Research Areas 5

  1. Nanotechnology/Materials / Polymer chemistry

  2. Nanotechnology/Materials / Nanometer-scale chemistry

  3. Environmental Science/Agriculture Science / Environmental load reduction and remediation

  4. Natural Science / Biophysics, chemical physics and soft matter physics

  5. Natural Science / Biophysics, chemical physics and soft matter physics

Current Research Project and SDGs 1

  1. Conversion of biomass and plastic waste to valuable materials

Research History 4

  1. Nanyang Technological University   School of Biological Science   Visiting Associate Professor

    2016.9 - 2017.3

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    Country:Singapore

  2. Nagoya University   Graduate School of Environmental Studies   Associate professor

    2010.12

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    Country:Japan

  3. Nagoya University   Graduate School of Environmental Studies   Lecturer

    2007.1 - 2010.11

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    Country:Japan

  4. Kyoto University   School of Science   Research Fellow

    2004.4 - 2006.12

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    Country:Japan

Education 2

  1. Nagoya University   Graduate School of Environmental Studies   Department of Environmental Engineering and Architecture

    2001.4 - 2004.3

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    Country: Japan

  2. Moscow State University   Graduate School, Division of Chemistry   Polymers

    1995.9 - 2000.6

Professional Memberships 3

  1. American Chemical Society

  2. 日本化学会

  3. The society of Polymer Science

Awards 1

  1. Chemical Society of Japan Annual Meeting Best Presentation Award

    2009.4  

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    Country:Japan

 

Papers 147

  1. DNA-Chitosan Hydrogels: Formation, Properties, and Functionalization with Catalytic Nanoparticles Reviewed International coauthorship

    Morikawa K., Masubuchi Y., Shchipunov Y., Zinchenko A.

    ACS Applied Bio Materials     2021.1

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    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsabm.0c01533

    Scopus

  2. Internal Motion of Chromatin Fibers Is Governed by Dynamics of Uncompressed Linker Strands. Reviewed International coauthorship

    Biophysical Journal   Vol. 119 ( 11 ) page: 2326 - 2334   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2020.10.018

    Web of Science

    Scopus

    PubMed

  3. Compaction and self-association of megabase-sized chromatin are induced by anionic protein crowding Reviewed International coauthorship

    Zinchenko Anatoly, Chen Qinming, Berezhnoy Nikolay V, Wang Sai, Nordenskiold Lars

    Sort Matter   Vol. 16 ( 18 ) page: 4366 - 4372   2020.5

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d0sm00162g

    Web of Science

    Scopus

    PubMed

  4. Amino Acid Sequence of Oligopeptide Causes Marked Difference in DNA Compaction and Transcription Reviewed

    Zinchenko Anatoly, Hiramatsu Hiroyuki, Yamaguchi Hideaki, Kubo Koji, Murata Shizuaki, Kanbe Toshio, Hazemoto Norio, Yoshikawa Kenichi, Akitaya Tatsuo

    Biophysical Journal   Vol. 116 ( 10 ) page: 1836 - 1844   2019.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2019.04.010

    Web of Science

    Scopus

    PubMed

  5. Small DNA Additives to Polyelectrolyte Multilayers Promote Formation of Ultrafine Gold Nanoparticles with Enhanced Catalytic Activity Invited Reviewed

    Nagahama C., Zinchenko A.

    Colloid and Polymer Science   Vol. 297   page: 363–369   2019.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00396-018-4432-6

  6. Hybrid porous magnetic bentonite-chitosan beads for selective removal of radioactive cesium in water. Reviewed

    Wang K, Ma H, Pu S, Yan C, Wang M, Yu J, Wang X, Chu W, Zinchenko A

    Journal of Hazardous Materials   Vol. 362   page: 160-169 - 169   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jhazmat.2018.08.067

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    PubMed

  7. Encapsulation of Long Genomic DNA into a Confinement of a Polyelectrolyte Microcapsule: A Single-Molecule Insight Reviewed

    Zinchenko Anatoly, Inagaki Eisuke, Murata Shizuaki

    ACS OMEGA   Vol. 4 ( 1 ) page: 458 - 464   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsomega.8b02865

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  8. A highly efficient magnetic chitosan “fluid” adsorbent with a high capacity and fast adsorption kinetics for dyeing wastewater purification Reviewed

    Ma Hui, Pu Shengyan, Hou Yaqi, Zhu Rongxin, Zinchenko Anatoly, Chu Wei

    Chemical Engineering Journal   Vol. 345   page: 556 - 565   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier B.V.  

    A novel magnetic fluid adsorbent (magnetic chitosan “fluid” MCF) was prepared via a one-step in situ co-precipitation procedure using inexpensive and environmentally friendly chitosan (CS) and iron precursor. The resultant ultrafine colloid was characterized using transmission electron microscopy (TEM), X-ray powder diffraction (XRD), thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR). The sorption and desorption characteristics of the composite were studied using a common Congo Red (CR) anionic dye to evaluate the suitability of the MCF for anionic dye wastewater purification. As an important advantage, the dye adsorption could be achieved in a wide alkaline pH range and reached the equilibrium within 5 min demonstrating the superior properties of our material compared the previously reported CS-based adsorbents. The adsorption obeyed the Langmuir isotherm model with the remarkable maximum adsorption capacity of approx. 1700 mg/g for CR under neutral pH. NaOH treatment was utilized to desorb and regenerate MCF, while the removal rate still remained above 90% after recycling five times, demonstrating that the MCF could be employed for repeated use without significant capacity loss. MCF could be readily separated from water within 30 s under a low magnetic field (&lt
    0.035 T). Overall, the ultrafine colloidal state of the synthesized MCF enabled a rapid pollutant uptake, high adsorption capacity, and reusability. The above characteristics of MCF and its environmentally friendly composition make it a very promising material for practical dyeing wastewater purification.

    DOI: 10.1016/j.cej.2018.03.115

    Web of Science

    Scopus

  9. Efficient prevention of nanomaterials transport in the porous media by treatment with polyelectrolytes Reviewed

    Soenaryo T., Murata S., Zinchenko A.

    Chemosphere   Vol. 210   page: 567-576   2018.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.chemosphere.2018.07.037

  10. Compaction of Single Molecule Megabase-Long Chromatin under the Influence of Macromolecular Crowding Reviewed

    Zinchenko A., Berezhnoy N., Chen Q., Nordenskiöld L.

    Biophysical Journal   Vol. 114   page: 2326–2335   2018.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bpj.2018.04.012

  11. Removal of Carbon Nanomaterials by Co-Precipitation with Chitosan: A Facile Method for Water Pre-Treatment Reviewed

    Soenaryo T., Zinchenko A., Murata S.

    Environmental Science: Water Research Technolology   Vol. 4   page: 265-271   2018.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/C7EW00283A

  12. Single-Molecule Compaction of Megabase-Long Chromatin Molecules by Multivalent Cations Reviewed

    Zinchenko A., Berezhnoy N., Wang S, Rosencrans W., Korolev N., van der Maarel J., Nordenskiöld L.

    Nucleic Acids Research   Vol. 2   page: 635-649   2018.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/nar/gkx1135

  13. Formation of Multi-Layered Chitosan Honeycomb Spheres via Breath-Figure-Like Approach in Combination with Co-Precipitation Processing Reviewed

    Ma H., Pu S.Y., Ma J., Yan C., Zinchenko A., Pei X., Chu W.

    Materials Letters   Vol. 211   page: 91-95   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.matlet.2017.09.091

  14. DNA-based materials as chemical reactors for synthesis of metal nanoparticles

    Zinchenko A., Sergeyev V. G.

    POLYMER SCIENCE SERIES C   Vol. 59 ( 1 ) page: 18-28   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1134/S1811238217010155

    Web of Science

  15. Novel highly porous magnetic hydrogel beads composed of chitosan and sodium citrate: an effective adsorbent for the removal of heavy metals from aqueous solutions Reviewed

    Pu S.Y., Ma H., Zinchenko A., Chu W.

    Environmental Science and Pollution Research   Vol. 24 ( 19 ) page: 16520-16530   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11356-017-9213-0

  16. Photoinduced Fusion of Lipid Bilayer Membranes Reviewed

    Suzuki Y., Nagai K., Zinchenko A., Hamada T.

    Languir   Vol. 33 ( 10 ) page: 2671-2676   2017.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.langmuir.7b00448

  17. An efficient heterogeneous fenton catalyst based on modified diatomite for degradation of cationic dye simulated wastewater Reviewed

    Pu S.Y., Xiang C., Zhu R., Ma H., Zinchenko A., Chu W.

    Desalination Water Treat.   Vol. 79   page: 378-385   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5004/dwt.2017.20824

  18. 大学の廃棄物のキャンパスマインとしての活用への提言(1) ─ 名古屋大学における廃試薬の調査に基づく考察 Reviewed

    ジンチェンコ アナトーリ, 竹田 裕哉, 三品 太志, 村田 静昭, 陳 寧

    環境と安全   Vol. 7   page: 17   2016.4

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  19. 大学の廃棄物のキャンパスマインとしての活用への提言(1) ─ 名古屋大学における廃試薬の調査に基づく考察 Reviewed

    ジンチェンコ アナトーリ, 竹田 裕哉, 三品 太志, 村田 静昭, 陳 寧

    環境と安全   Vol. 7   page: 17   2016.4

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  20. Gold Nanoparticles in DNA-Based Multilayer Films: Synthesis, Size Control, and Influence of the Multilayer Structure on Au NP Catalytic Properties Reviewed

    Zinchenko A, Nagahama C, Murata. S

    ChemNanoMat   Vol. 2016 ( 2 ) page: 125-132   2016.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/cnma.201600012

  21. DNA Conformational Behavior and Compaction in Biomimetic Systems: Toward Better Understanding of DNA Packaging in Cel Reviewed

    Zinchenko A.

    Adv. Colloid. Interface Sci.   Vol. 2016 ( 232 ) page: 70-79   2016.1

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    Authorship:Lead author   Language:English  

    DOI: 10.1016/j.cis.2016.02.005

  22. Decoration of DNA scaffold by gold nanoparticles formed in aqueous solutions Reviewed

    Lopatina L.I., Karpushkin E.A., Zinchenko A., Sergeyev V.G.

    Mendeleyev Comm.   Vol. 26   page: 291‐292   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.mencom.2016.07.007

  23. Fabrication of Bimetallic Core-Shell and Alloy Ag-Au Nanoparticles on a DNA Template Reviewed

    Taniguchi S., Zinchenko A., Murata. S.

    Chem.Lett.   Vol. 45   page: 610‐611   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1246/cl.160180

  24. Divalent cation shrinks DNA but inhibits its compaction with trivalent cation Reviewed

    Tongu C., Kenmotsu T., Yoshikawa Y., Zinchenko A., Chen N., Yoshikawa K.*

    J. Chem. Phys.   Vol. 144   page: 205101   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1063/1.4950749

  25. Metallization of DNA Hydrogel - Application of Soft Matter Host for Preparation and Nesting of Catalytic Nanoparticles Reviewed

    Zinchenko A., Che Y., Taniguchi S., Lopatina L.I., Sergeyev V.G.,Murata S.

    J.Nanopart. Res.   Vol. 18   page: 179   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s11051-016-3480-4

  26. Size Dependent Catalytic Activity of Gold Nanoparticles in DNA Hydrogels Reviewed

    Zinchenko A. Taniguchi S., Murata. S.

    Macromolecular Symposia   Vol. 2015 ( 129 ) page: 106-111   2015.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/masy.201500062

  27. DNAの資源化

    ジンチェンコ アナトーリ

    化学と工業   Vol. 68 ( 9 ) page: 804-805   2015.9

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    Authorship:Lead author   Language:Japanese  

  28. DNAの資源化

    ジンチェンコ アナトーリ

    化学と工業   Vol. 68 ( 9 ) page: 804-805   2015.9

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  29. Solubilization of MWCNT by DNA and Construction of DNA-MWCNT Hybrid Hydrogels Reviewed

    Zinchenko A., Taki Y., Sergeyev V.G., Murata S.

    Nanomaterials   Vol. 2015 ( 5 ) page: 270-283   2015.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  30. Uptake of Aromatic Compounds by DNA: Toward the Environmental Application of DNA for Cleaning Water Reviewed

    Fernández-Solis C., Kuroda Y., Zinchenko A., Murata S.

    Colloids Surf., B.   Vol. 2015 ( 129 ) page: 146–153   2015.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  31. Solubilization of MWCNT by DNA and Construction of DNA-MWCNT Hybrid Hydrogels Reviewed

    Zinchenko A, Taki Y, Sergeyev V.G, Murata S

    Nanomaterials   Vol. 2015 ( 5 ) page: 270-283   2015.2

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  32. Uptake of Aromatic Compounds by DNA: Toward the Environmental Application of DNA for Cleaning Water Reviewed

    Fernández-Solis C, Kuroda Y, Zinchenko A, Murata S

    Colloids Surf., B.   Vol. 2015 ( 129 ) page: 146–153   2015.2

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  33. Compaction of Double-Stranded DNA by Negatively Charged Proteins and Colloids Reviewed

    Zinchenko A., Yoshikawa K.

    Curr. Opin. Colloid Interface Sci.   Vol. 2015 ( 20 ) page: 60-65   2015.1

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  34. Control of a Catalytic Activity of Gold Nanoparticles Embedded in DNA Hydrogel by Swelling/Shrinking the Hydrogel's Matrix Reviewed

    Che Y., Zinchenko A., Murata S.

    J. Colloid Interface Sci.   Vol. 2015 ( 445 ) page: 364-370   2015.1

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  35. Compaction of Double-Stranded DNA by Negatively Charged Proteins and Colloids Reviewed

    Zinchenko A, Yoshikawa K

    Curr. Opin. Colloid Interface Sci.   Vol. 2015 ( 20 ) page: 60-65   2015.1

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  36. Control of a Catalytic Activity of Gold Nanoparticles Embedded in DNA Hydrogel by Swelling/Shrinking the Hydrogel's Matrix Reviewed

    Che Y, Zinchenko A, Murata S

    J. Colloid Interface Sci.   Vol. 2015 ( 445 ) page: 364-370   2015.1

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  37. Entrapment and Removal of Carbon Nanotubes and Fullerenes by Co-Precipitation with Calcium Carbonate Beads Reviewed

    Pu S.Y, Zinchenko A.A., Chen N., Murata S.

    ACS Sustainable Chem. Eng.   Vol. 2014 ( 2 ) page: 2275−2282   2014.9

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  38. Entrapment and Removal of Carbon Nanotubes and Fullerenes by Co-Precipitation with Calcium Carbonate Beads Reviewed

    Pu S.Y, Zinchenko A.A, Chen N, Murata S

    ACS Sustainable Chem. Eng.   Vol. 2014 ( 2 ) page: 2275-2282   2014.9

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  39. DNA Hydrogel as a Template for Synthesis of Ultrasmall Gold Nanoparticles for Catalytic Applications Reviewed

    Zinchenko A. A., Miwa, Y., Lopatina L.I., Sergeyev V.G., Murata S.

    ACS Appl. Mater. Interfaces   Vol. 6 ( 5 ) page: 3226–3232.   2014

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  40. Size Control of Gold Nanoparticles Synthesized in a DNA Hydrogel Reviewed

    Miwa, Y., Zinchenko A. A., Lopatina L.I., Sergeyev V.G., Murata S.

    Polym. Int.   Vol. 63 ( 9 ) page: 1566-1571   2014

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  41. Crowding by anionic nanoparticles causes DNA double-strand instability and compaction Reviewed

    Zinchenko, A.; Tsumoto, K.; Murata, S.; Yoshikawa, K.

    J. Phys. Chem.   Vol. 118 ( 5 ) page: 1256-1262   2014

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  42. Photochemical metallization to fabricate DNA-templated gold nanorings Reviewed

    Pu S.Y, Zinchenko A.A., Qina L., Xua M., M. Xu., Murata S.

    Mater. Lett.   Vol. 130   page: 168-171   2014

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  43. Crowding by anionic nanoparticles causes DNA double-strand instability and compaction Reviewed

    Zinchenko, A, Tsumoto, K, Murata, S, Yoshikawa, K

    J. Phys. Chem.   Vol. 118 ( 5 ) page: 1256-1262   2014

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  44. DNA Hydrogel as a Template for Synthesis of Ultrasmall Gold Nanoparticles for Catalytic Applications Reviewed

    Zinchenko A. A, Miwa, Y, Lopatina L.I, Sergeyev V.G, Murata S

    ACS Appl. Mater. Interfaces   Vol. 6 ( 5 ) page: 3226–3232.   2014

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  45. Photochemical metallization to fabricate DNA-templated gold nanorings Reviewed

    Pu S.Y, Zinchenko A.A, Qina L, Xua M, M. Xu, Murata S

    Mater. Lett.   Vol. 130   page: 168-171   2014

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  46. Size Control of Gold Nanoparticles Synthesized in a DNA Hydrogel Reviewed

    Miwa, Y, Zinchenko A. A, Lopatina L.I, Sergeyev V.G, Murata S

    Polym. Int.   Vol. 63 ( 9 ) page: 1566-1571   2014

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  47. Extraction of Noble and Rare-Earth Metals from Aqueous Solutions by DNA Cross-Linked Hydrogel Reviewed

    Maeda Y., Zinchenko A. A., Murata S.

    ChemPlusChem   Vol. 78 ( 7 ) page: 619-622   2013

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  48. Entrapping of Fullerenes, Nanotubes, and Inorganic Nanoparticles by a DNA-Chitosan Complex: A Method for Nanomaterials Removal Reviewed

    Zinchenko A. A., Maeda N., Pu S.Y., Murata S.

    Environ. Sci. Technol.   Vol. 47 ( 9 ) page: 4489-4496   2013

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  49. Entrapping of Fullerenes, Nanotubes, and Inorganic Nanoparticles by a DNA-Chitosan Complex: A Method for Nanomaterials Removal Reviewed

    Zinchenko A. A, Maeda N, Pu S.Y, Murata S

    Environ. Sci. Technol.   Vol. 47 ( 9 ) page: 4489-4496   2013

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  50. Extraction of Noble and Rare-Earth Metals from Aqueous Solutions by DNA Cross-Linked Hydrogel Reviewed

    Maeda Y, Zinchenko A. A, Murata S

    ChemPlusChem   Vol. 78 ( 7 ) page: 619-622   2013

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  51. Photochemical Modulation of DNA Conformation by Organic Dications Reviewed

      Vol. 13   page: 105-111   2012

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  52. Templating of inorganic nanomaterials by biomacromolecules and their assemblies Invited Reviewed

      Vol. 54 ( 7 ) page: 1048-1055   2012

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  53. Facile Control of DNA-Templated Inorganic Nanoshell Size Reviewed

      Vol. 12   page: 635-641   2012

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  54. Thiol-Mediated Anchoring of Silver Cations to DNA for Construction of Nanofibers on DNA Scaffold Reviewed

      Vol. 13 ( 6 ) page: 1787-1793   2012

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  55. Facile Control of DNA-Templated Inorganic Nanoshell Size Reviewed

    Pu S. Y, Zinchenko A. A, Murata S

    J. Nanosci. Nanotechnol   Vol. 12   page: 635-641   2012

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  56. Photochemical Modulation of DNA Conformation by Organic Dications Reviewed

    Zinchenko A. A, Tanahashi M, Murata S

    ChemBioChem   Vol. 13   page: 105-111   2012

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  57. Templating of inorganic nanomaterials by biomacromolecules and their assemblies Invited Reviewed

    Zinchenko A. A

    Polymer Science C   Vol. 54 ( 7 ) page: 1048-1055   2012

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  58. Thiol-Mediated Anchoring of Silver Cations to DNA for Construction of Nanofibers on DNA Scaffold Reviewed

    Zinchenko A. A, Chen N, Baigl D, Lopatina L, Sergeyev V. G

    Biomacromolecules   Vol. 13 ( 6 ) page: 1787-1793   2012

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  59. A Facile Method for the Assessment of DNA Damage Induced by UV-Activated Nanomaterials Reviewed

    Yamazaki Y, Zinchenko A. A, Murata S

    Nanoscale   Vol. 3 ( 7 ) page: 2909-2915   2011

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  60. A Facile Method for the Assessment of DNA Damage Induced by UV-Activated Nanomaterials Reviewed

    Yamazaki Y., Zinchenko A. A., Murata S.

    Nanoscale   Vol. 3 ( 7 ) page: 2909-2915   2011

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  61. Effects of Cationic and Anionic Nanoparticles on the Stability of the Secondary Structure of DNA Reviewed

    Kamata H., Zinchenko A. A., Murata S.

    Colloid Polym. Sci.   Vol. 289   page: 1329-1335   2011

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  62. Conformational behavior of DNA-templated CdS inorganic nanowiren of Hollow Meshed Inorganic Nanoshells Reviewed

    Pu S. Y., Zinchenko A. A., Murata S.

    Nanotechnology   Vol. 22   page: 375604   2011

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  63. Facile Control of DNA-Templated Inorganic Nanoshell Size Reviewed

    Pu S. Y., Zinchenko A. A., Murata S.

    J. Nanosci. Nanotechnol.     page: in press   2011

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  64. DNA-Assisted "Double-Templating" Approach for the Construction of Hollow Meshed Inorganic Nanoshells Reviewed

    Pu S. Y., Zinchenko A. A., Murata S.

    Langmuir   Vol. 27 ( 8 ) page: 5009-5013   2011

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  65. Conformational behavior of DNA-templated CdS inorganic nanowiren of Hollow Meshed Inorganic Nanoshells Reviewed

    Pu S. Y, Zinchenko A. A, Murata S

    Nanotechnology   Vol. 22   page: 375604   2011

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  66. DNA-Assisted "Double-Templating" Approach for the Construction of Hollow Meshed Inorganic Nanoshells Reviewed

    Pu S. Y, Zinchenko A. A, Murata S

    Langmuir   Vol. 27 ( 8 ) page: 5009-5013   2011

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  67. A facile method for the assessment of DNA damage induced by UV-activated nanomaterials

    Yuka Yamazaki, Anatoly A. Zinchenko, Shizuaki Murata

    NANOSCALE   Vol. 3 ( 7 ) page: 2909 - 2915   2011

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ROYAL SOC CHEMISTRY  

    Fluorescent microscopy observation of gene-size DNA (T4 phage DNA or l phage DNA) was used to assess DNA damage induced by UV irradiation in the presence of nanomaterials, such as QDs (quantum dots: CdSe/ZnS semiconductor nanoparticles), the water-soluble fullerene derivative C(60)(OH)(n) (n = 6-12) and titanium oxide nanoparticles of 25 nm in diameter. The magnitude of DNA damage could be simply evaluated based on the degree of shortening of the stretched DNA image. This method showed that DNA damage was amplified by the action of QDs under irradiation by C-band (lambda(max) = 254 nm) or B-band (lambda(max) = 303 nm) UV. Smaller QDs that emitted higher-energy fluorescence (lambda(em)(max) = 565 nm) induced more severe damage than medium-and larger-size QDs that emitted longer-wavelength fluorescence (lambda(em)(max) 605 and 705 nm, respectively). The fullerene derivative and TiO(2) nanoparticles caused DNA damage even under irradiation by A-band UV (lambda(max) = 365 nm) and showed more severe DNA damage than QDs under similar conditions.

    DOI: 10.1039/c1nr10238a

    Web of Science

    Scopus

    PubMed

  68. Effects of Cationic and Anionic Nanoparticles on the Stability of the Secondary Structure of DNA Reviewed

    Kamata H, Zinchenko A. A, Murata S

    Colloid Polym. Sci.   Vol. 289   page: 1329-1335   2011

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  69. Facile Control of DNA-Templated Inorganic Nanoshell Size Reviewed

    Pu S. Y, Zinchenko A. A, Murata S

    J. Nanosci. Nanotechnol.     page: in press   2011

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  70. Compaction Induced by Histone-Mimic Nanoparticles Reviewed

    Takenaka T, Zinchenko A. A, Yoshikawa K, Murata S

    Bull. Chem. Soc. Jap.   Vol. 83   page: 643-650   2010

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  71. Compaction Induced by Histone-Mimic Nanoparticles Reviewed

    Takenaka T, Zinchenko A. A, Yoshikawa K, Murata S

    Bull. Chem. Soc. Jap.   Vol. 83   page: 643-650   2010

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  72. DNA Compaction on Histone Mimics Prepared from Silica Nanoparticles Reviewed

    Takenaka T., Zinchenko A. A., Yoshikawa K., Murata S.

    Chemistry Letters   Vol. 39   page: 72-73   2010

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  73. Quantum dot probes for observation of single molecule DNA and a synthetic polyelectrolyte higher-order structure Reviewed

    Chen N., Zinchenko A. A., Yamazaki Y., Yoshikawa Y., Murata S., Yoshikawa K.

    Soft Matter   Vol. 6   page: 2834 - 2841   2010

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  74. Roles of Mono- and Divalent Cations in DNA Compaction Induced by Histone-Mimic Nanoparticles Reviewed

    Takenaka T., Zinchenko A. A., Yoshikawa K., Murata S.

    Bulletin of the Chemical Society of Japan   Vol. 83   page: 643-650   2010

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  75. Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly(N-isopropylacrylamide) Reviewed

    Chen N., Zinchenko A. A., Kidoaki S., Murata S., Yoshikawa K.

    Langmuir   Vol. 26 ( 5 ) page: 2995-2998   2010

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  76. Compaction Induced by Histone-Mimic Nanoparticles Reviewed

    Takenaka T., Zinchenko A. A., Yoshikawa K., Murata S.

    Bull. Chem. Soc. Jap.   Vol. 83   page: 643-650   2010

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  77. Quantum dot probes for observation of single molecule DNA and a synthetic polyelectrolyte higher-order structure Reviewed

    Chen N., Zinchenko A. A., Yamazaki Y., Yoshikawa Y., Murata S., Yoshikawa K.

    Soft Matter   Vol. 6   page: 2834-2841   2010

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  78. DNA Compaction on Histone Mimics Prepared from Silica Nanoparticles Reviewed

    Takenaka T, Zinchenko A. A, Yoshikawa K, Murata S

    Chemistry Letters   Vol. 39   page: 72-73   2010

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  79. Quantum dot probes for observation of single molecule DNA and a synthetic polyelectrolyte higher-order structure Reviewed

    Chen N, Zinchenko A. A, Yamazaki Y, Yoshikawa Y, Murata S, Yoshikawa K

    Soft Matter   Vol. 6   page: 2834 - 2841   2010

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  80. Quantum dot probes for observation of single molecule DNA and a synthetic polyelectrolyte higher-order structure Reviewed

    Chen N, Zinchenko A. A, Yamazaki Y, Yoshikawa Y, Murata S, Yoshikawa K

    Soft Matter   Vol. 6   page: 2834-2841   2010

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  81. Roles of Mono- and Divalent Cations in DNA Compaction Induced by Histone-Mimic Nanoparticles Reviewed

    Takenaka T, Zinchenko A. A, Yoshikawa K, Murata S

    Bulletin of the Chemical Society of Japan   Vol. 83   page: 643-650   2010

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  82. Thermo-Switching of the Conformation of Genomic DNA in Solutions of Poly(N-isopropylacrylamide) Reviewed

    Chen N, Zinchenko A. A, Kidoaki S, Murata S, Yoshikawa K

    Langmuir   Vol. 26 ( 5 ) page: 2995-2998   2010

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  83. Application of DNA condensation for removal of mercury ions from aqueous solutions

    A. A. Zinchenko, H. Sakai, S. Matsuoka, S. Murata

    JOURNAL OF HAZARDOUS MATERIALS   Vol. 168 ( 1 ) page: 38 - 43   2009.8

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    DNA has a unique character that allows it to combine with various chemical substrates at the molecular level, and the DNA binding with chemical pollutants can cause serious damage to the organism. The purpose of this research was to apply the strong bonding character of DNA for the removal of mercury ions. In this research, we used DNA condensation promoted by the action of DNA condensing agents, such as cetyltrimethylammonium bromide and a commercially available combination flocculant made of zeolite, to precipitate out the DNA bound with mercury ion in an aqueous solution. When solutions of mercury at 0.02-100 ppm (parts per million) concentrations at a pH range of 2-11 were treated with double-stranded DNA followed by the condensing agent, more than 95% of the mercury ions could be removed after simple filtration or sedimentation. (C) 2009 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.jhazmat.2009.01.121

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    Scopus

  84. Assessment of the DNA damage using the fluorescence microscope Reviewed

    Yamazaki Y, Zinchenko A. A, Murata S

    Nucleic Acids Symp. Ser.   Vol. 53   page: 47-48   2009

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  85. *Application of DNA condensation for removal of mercury ions from aqueous solutions Reviewed

    Zinchenko A. A, Sakai H, Matsuoka S, Murata S

    Journal of Hazardous Materials   Vol. 168 ( 1 ) page: 38-43   2009

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  86. *Application of DNA condensation for removal of mercury ions from aqueous solutions Reviewed

    Zinchenko A. A., Sakai H., Matsuoka S., Murata S.

    Journal of Hazardous Materials   Vol. 168 ( 1 ) page: 38-43   2009

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  87. Removal of heavy metal ions from aqueous solutions by complexation with DNA and precipitation with cationic surfactant Reviewed

    Sakai H., Matsuoka S., Zinchenko A. A., Murata S.

    Colloids Surf., A.   Vol. 347   page: 210–214   2009

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  88. Assessment of the DNA damage using the fluorescence microscope Reviewed

    Yamazaki Y., Zinchenko A. A., Murata S.

    Nucleic Acids Symp. Ser.   Vol. 53   page: 47-48   2009

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  89. Removal of heavy metal ions from aqueous solutions by complexation with DNA and precipitation with cationic surfactant Reviewed

    Sakai H, Matsuoka S, Zinchenko A. A, Murata S

    Colloids Surf., A.   Vol. 347   page: 210–214   2009

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  90. ATP-induced shrinkage of DNA with MukB protein and MukBEF complex of Escherichia coli Reviewed

    Chen N, Zinchenko A.A, Yoshikawa Y, Araki S, Adachi S, Yamazoe M, Hiraga S, Yoshikawa K

    Journal of Bacteriology   Vol. 190 ( 10 ) page: 3731-3737   2008

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    Fluorescence microscopic observation on individual T4 DNA molecules revealed that MukBEF complex (bacterial condensin) and its subunit MukB (a member of SMC superfamily) homodimer of Escherichia coli shrunk markedly large DNA molecules in the presence of hydrolysable ATP. Contrary, in the presence of ADP or ATP-γS, the conformation of DNA was almost not changed. This suggests that the ATPase activity of subunit MukB is essential to shrink large DNA molecules. Stretching experiment on the shrunken DNA in the presence of ATP and MukBEF indicated cross bridging interaction between DNA molecules.

  91. A Novel Type Cationic Silica Nanoparticles and its Potential Application in Biomedicine Reviewed

    Li L, Takenaka T, Zinchenko A, Chen N, Ma Y, Yoshikawa K

    Proceedings of International Conference on Bioinformatics and Biomedical Engineering (ICBBE) 2008     page: 1539-1542   2008

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  92. *Photochemical Metallization of DNA Reviewed

    Zinchenko A. A, Chen N, Murata S

    Chemistry Letters   Vol. 37   page: 1096-1097   2008

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    We have shown that upon UV irradiation of silver(I) ion solutions containing alcohol as reduction agents, metal nanoparticles are grown on a DNA polymer chain. This metallization is independent of the DNA double-helicity and is controlled by the chemical structure of alcohol as well as by the wavelength of the light source.

  93. *Photochemical Metallization of DNA Reviewed

    Zinchenko A. A., Chen N., Murata S.

    Chemistry Letters   Vol. 37   page: 1096-1097   2008

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    We have shown that upon UV irradiation of silver(I) ion solutions containing alcohol as reduction agents, metal nanoparticles are grown on a DNA polymer chain. This metallization is independent of the DNA double-helicity and is controlled by the chemical structure of alcohol as well as by the wavelength of the light source.

  94. Conformational Behavior of Giant DNA through Binding with Ag+ and Metallization Reviewed

    Zinchenko A. A., Baigl D, Chen N., Pyshkina O. A., Endo K., Sergeyev V. G., Yoshikawa K.

    Biomacromolecules   Vol. 9   page: 1981-1987   2008

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  95. ATP-induced shrinkage of DNA with MukB protein and MukBEF complex of Escherichia coli Reviewed

    Chen N., Zinchenko A.A., Yoshikawa Y., Araki S., Adachi S., Yamazoe M., Hiraga S., Yoshikawa K.

    Journal of Bacteriology   Vol. 190 ( 10 ) page: 3731-3737   2008

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    Language:English   Publishing type:Research paper (scientific journal)  

    Fluorescence microscopic observation on individual T4 DNA molecules revealed that MukBEF complex (bacterial condensin) and its subunit MukB (a member of SMC superfamily) homodimer of Escherichia coli shrunk markedly large DNA molecules in the presence of hydrolysable ATP. Contrary, in the presence of ADP or ATP-γS, the conformation of DNA was almost not changed. This suggests that the ATPase activity of subunit MukB is essential to shrink large DNA molecules. Stretching experiment on the shrunken DNA in the presence of ATP and MukBEF indicated cross bridging interaction between DNA molecules.

  96. Single-Molecule Observations of Giant DNA and Synthetic Polyelectrolyte by Labeling with Semiconductor "Quantum Dots" Reviewed

    Chen N., Yamazaki Y., Zinchenko A., Yoshikawa Y., Murata S., Yoshikawa K.

    Proceedings of International Symposium on Micro-Nano Mechatronics and Human Science     page: 140-144   2008

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  97. A Novel Type Cationic Silica Nanoparticles and its Potential Application in Biomedicine Reviewed

    Li L., Takenaka T., Zinchenko A., Chen N., Ma Y., Yoshikawa K.

    Proceedings of International Conference on Bioinformatics and Biomedical Engineering (ICBBE) 2008     page: 1539-1542   2008

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  98. Conformational Behavior of Giant DNA through Binding with Ag+ and Metallization Reviewed

    Zinchenko A. A, Baigl D, Chen N, Pyshkina O. A, Endo K, Sergeyev V. G, Yoshikawa K

    Biomacromolecules   Vol. 9   page: 1981-1987   2008

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  99. Single-Molecule Observations of Giant DNA and Synthetic Polyelectrolyte by Labeling with Semiconductor "Quantum Dots" Reviewed

    Chen N, Yamazaki Y, Zinchenko A, Yoshikawa Y, Murata S, Yoshikawa K

    Proceedings of International Symposium on Micro-Nano Mechatronics and Human Science     page: 140-144   2008

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  100. *Transcription of Giant DNA Complexed with Cationic Nanoparticles as a Simple Model of Chromatin Reviewed

    Zinchenko A. A, Luckel F, Yoshikawa K

    Biophysical Journal   Vol. 92   page: 1318-1325   2007

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  101. *Transcription of Giant DNA Complexed with Cationic Nanoparticles as a Simple Model of Chromatin Reviewed

    Zinchenko A. A., Luckel F., Yoshikawa K.

    Biophysical Journal   Vol. 92   page: 1318-1325   2007

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  102. Dynamic Conformational Behavior and Molecular Interaction Discrimination of DNA/Binder Complexes by Single-Chain Stretching in a MicroDevice Reviewed

    Huang W.-H., Zinchenko A. A., Pawlak C., Chen Y., Baigl D.

    ChemBioChem   Vol. 8 ( 15 ) page: 1771-1774   2007

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  103. Single-Chain Compaction of Long Duplex DNA by Cationic Nanoparticles: Modes of Interaction and Comparison with Chromatin Reviewed

    Zinchenko A. A., Sakaue T., Araki S., Yoshikawa K., Baigl D.

    Journal of Physical Chemistry B   Vol. 111   page: 3019 -3031   2007

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    The compaction of long duplex DNA by cationic nanoparticles (NP) used as a primary model of histone core particles has been investigated. We have systematically studied the effect of salt concentration, particle size, and particle charge by means of single-molecule observations-fluorescence microscopy (FM) and transmission electron microscopy (TEM)-and molecular dynamics (MD) simulations. We have found that the large-scale DNA compaction is progressive and proceeds through the formation of beads-on-a-string structures of various morphologies. The DNA adsorbed amount per particle depends weakly on NP concentration but increases significantly with an increase in particle size and is optimal at an intermediate salt concentration. Three different complexation mechanisms have been identified depending on the correlation between DNA and NPs in terms of geometry, chain rigidity, and electrostatic interactions: free DNA adsorption onto NP surface, DNA wrapping around NP, and NP collection on DNA chain.

  104. Visualization of Different Pathways of DNA Release from Interpolyelectrolyte Complex Reviewed

    Ayoubi M. A., Zinchenko A. A., Philippova O. E, Khokhlov A. R., Yoshikawa K.

    Journal of Physical Chemistry B   Vol. 111   page: 8378-8378   2007

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    Fluorescence microscopy is used for visualizing the release of double-stranded DNA from its interpolyelectrolyte complex with positively charged poly(allylamine hydrochloride) though exchange reaction with added polyanion, poly(sodium styrenesulfonate). The switching of pathway of DNA release is due to the screening of electrostatic repulsion in charged sequences of naked DNA and the decrease of the osmotic pressure of counterions.

  105. Dynamic Conformational Behavior and Molecular Interaction Discrimination of DNA/Binder Complexes by Single-Chain Stretching in a MicroDevice Reviewed

    Huang W.-H., Zinchenko A. A., Pawlak C., Chen Y., Baigl D.

    ChemBioChem   Vol. 8 ( 15 ) page: 1771-1774   2007

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    The compaction of DNA is an essential step in several biological applications, including gene delivery.[1] During the past two decades many studies have been devoted to the in vitro compaction of DNA, and various compaction agents have been identified, such as polycations, multivalent metal cations, hydrophilic polymers and surfactants.[2] The manipulation of the unfolding and folding of DNA is considered to be a key to controlling its biological activity. On the other hand, it is known that DNA molecules can be stretched from the random coil to an elongated state[3] by using microfluidic or electrodynamical methods.[4] However, such an approach has never been applied to DNA in a compact state. In this communication, we report on the use of a microfluidic device to study the unfolding process of compact single-chain DNA and its relationship with the molecular interaction between DNA and compaction/binding molecules.

  106. Dynamic Conformational Behavior and Molecular Interaction Discrimination of DNA/Binder Complexes by Single-Chain Stretching in a MicroDevice Reviewed

    Huang W.-H, Zinchenko A. A, Pawlak C, Chen Y, Baigl D

    ChemBioChem   Vol. 8 ( 15 ) page: 1771-1774   2007

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  107. Dynamic Conformational Behavior and Molecular Interaction Discrimination of DNA/Binder Complexes by Single-Chain Stretching in a MicroDevice Reviewed

    Huang W.-H, Zinchenko A. A, Pawlak C, Chen Y, Baigl D

    ChemBioChem   Vol. 8 ( 15 ) page: 1771-1774   2007

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    Language:English   Publishing type:Research paper (scientific journal)  

    The compaction of DNA is an essential step in several biological applications, including gene delivery.[1] During the past two decades many studies have been devoted to the in vitro compaction of DNA, and various compaction agents have been identified, such as polycations, multivalent metal cations, hydrophilic polymers and surfactants.[2] The manipulation of the unfolding and folding of DNA is considered to be a key to controlling its biological activity. On the other hand, it is known that DNA molecules can be stretched from the random coil to an elongated state[3] by using microfluidic or electrodynamical methods.[4] However, such an approach has never been applied to DNA in a compact state. In this communication, we report on the use of a microfluidic device to study the unfolding process of compact single-chain DNA and its relationship with the molecular interaction between DNA and compaction/binding molecules.

  108. Single-Chain Compaction of Long Duplex DNA by Cationic Nanoparticles: Modes of Interaction and Comparison with Chromatin Reviewed

    Zinchenko A. A, Sakaue T, Araki S, Yoshikawa K, Baigl D

    Journal of Physical Chemistry B   Vol. 111   page: 3019 -3031   2007

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    Language:English   Publishing type:Research paper (scientific journal)  

    The compaction of long duplex DNA by cationic nanoparticles (NP) used as a primary model of histone core particles has been investigated. We have systematically studied the effect of salt concentration, particle size, and particle charge by means of single-molecule observations-fluorescence microscopy (FM) and transmission electron microscopy (TEM)-and molecular dynamics (MD) simulations. We have found that the large-scale DNA compaction is progressive and proceeds through the formation of beads-on-a-string structures of various morphologies. The DNA adsorbed amount per particle depends weakly on NP concentration but increases significantly with an increase in particle size and is optimal at an intermediate salt concentration. Three different complexation mechanisms have been identified depending on the correlation between DNA and NPs in terms of geometry, chain rigidity, and electrostatic interactions: free DNA adsorption onto NP surface, DNA wrapping around NP, and NP collection on DNA chain.

  109. Visualization of Different Pathways of DNA Release from Interpolyelectrolyte Complex Reviewed

    Ayoubi M. A, Zinchenko A. A, Philippova O. E, Khokhlov A. R, Yoshikawa K

    Journal of Physical Chemistry B   Vol. 111   page: 8378-8378   2007

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    Language:English   Publishing type:Research paper (scientific journal)  

    Fluorescence microscopy is used for visualizing the release of double-stranded DNA from its interpolyelectrolyte complex with positively charged poly(allylamine hydrochloride) though exchange reaction with added polyanion, poly(sodium styrenesulfonate). The switching of pathway of DNA release is due to the screening of electrostatic repulsion in charged sequences of naked DNA and the decrease of the osmotic pressure of counterions.

  110. Probing Biopolymer Conformation by Metallization with Noble Metals Reviewed

    Chen N., Zinchenko A. A., Yoshikawa K.

    Nanotechnology   Vol. 17   page: 5224-5232   2006

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  111. Na+ more strongly inhibits DNA compaction by spermidine (3+) than K+ Reviewed

    Hibino K., Yoshikawa Y., Murata S., Saito T., Zinchenko A. A., Yoshikawa K.

    Chemical Physics Letters   Vol. 426   page: 405-409   2006

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  112. Compaction of DNA on nanoscale three-dimensional templates Invited

    Zinchenko A. A., Chen N.

    Journal of Physics: Condensed Matter   Vol. 18   page: R453-R480   2006

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  113. Compaction of DNA on nanoscale three-dimensional templates Invited

    Zinchenko A. A, Chen N

    Journal of Physics: Condensed Matter   Vol. 18   page: R453-R480   2006

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  114. Na+ more strongly inhibits DNA compaction by spermidine (3+) than K+ Reviewed

    Hibino K, Yoshikawa Y, Murata S, Saito T, Zinchenko A. A, Yoshikawa K

    Chemical Physics Letters   Vol. 426   page: 405-409   2006

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  115. Probing Biopolymer Conformation by Metallization with Noble Metals Reviewed

    Chen N, Zinchenko A. A, Yoshikawa K

    Nanotechnology   Vol. 17   page: 5224-5232   2006

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  116. *Compaction of single-chain DNA by histone-inspired nanoparticles Reviewed

    Zinchenko A. A, Yoshikawa K, Baigl D

    Physical Review Letters   Vol. 95 ( 22 ) page: 228101   2005

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  117. *Compaction of single-chain DNA by histone-inspired nanoparticles Reviewed

    Zinchenko A. A., Yoshikawa K., Baigl D

    Physical Review Letters   Vol. 95 ( 22 ) page: 228101   2005

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  118. Na+ Shows a Markedly Higher Potential than K+ in DNA Compaction in a Crowded Environment Reviewed

    Zinchenko A. A., Yoshikawa K.

    Biophys. J.   Vol. 88(6)   page: 4118-4123   2005

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  119. DNA-templated silver nanorings Reviewed

    Zinchenko A. A., Yoshikawa K., Baigl D.

    Adv. Mater.   Vol. 17 ( 23 ) page: 2820-2823   2005

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  120. How Does DNA Compaction Favor Chiral Selectivity with Cationic Species? Higher Selectivity with Lower Cationic Charge Reviewed

    Zinchenko A. A., Chen N., Murata S., Yoshikawa K.

    ChemBioChem   Vol. 6(8)   page: 1419-1422   2005

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  121. Specific Formation of Beads-on-a-Chain Structures on Giant DNA Using a Designed Polyamine Derivative Reviewed

    Chen N., Zinchenko A. A., Murata S., Yoshikawa K.

    J. Am. Chem. Soc.   Vol. 127   page: 10910-10916   2005

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  122. DNA-templated silver nanorings Reviewed

    Zinchenko A. A, Yoshikawa K, Baigl D

    Adv. Mater.   Vol. 17 ( 23 ) page: 2820-2823   2005

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  123. How Does DNA Compaction Favor Chiral Selectivity with Cationic Species? Higher Selectivity with Lower Cationic Charge Reviewed

    Zinchenko A. A, Chen N, Murata S, Yoshikawa K

    ChemBioChem   Vol. 6(8)   page: 1419-1422   2005

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  124. Na+ Shows a Markedly Higher Potential than K+ in DNA Compaction in a Crowded Environment Reviewed

    Zinchenko A. A, Yoshikawa K

    Biophys. J.   Vol. 88(6)   page: 4118-4123   2005

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  125. Specific Formation of Beads-on-a-Chain Structures on Giant DNA Using a Designed Polyamine Derivative Reviewed

    Chen N, Zinchenko A. A, Murata S, Yoshikawa K

    J. Am. Chem. Soc.   Vol. 127   page: 10910-10916   2005

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  126. Stereoisomeric Discrimination in DNA Compaction Reviewed

    Zinchenko A. A., Sergeyev V. G., Kabanov V. A., Murata S., Yoshikawa K.

    Angewandte Chemie International Edition   Vol. 43 ( 18 ) page: 2378-2371   2004

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  127. DNA Compaction by the Divalent Cations: Structural Specificity Revealed by the Potentiality of the Designed Quaternary Diammonium Salts, Reviewed

    Zinchenko A. A., Sergeyev V. G., Yamabe K., Murata S., Yoshikawa K.

    ChemBioChem   Vol. 5 ( 3 ) page: 360-368   2004

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  128. DNA Compaction by the Divalent Cations: Structural Specificity Revealed by the Potentiality of the Designed Quaternary Diammonium Salts, Reviewed

    Zinchenko A. A, Sergeyev V. G, Yamabe K, Murata S, Yoshikawa K

    ChemBioChem   Vol. 5 ( 3 ) page: 360-368   2004

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  129. Stereoisomeric Discrimination in DNA Compaction Reviewed

    Zinchenko A. A, Sergeyev V. G, Kabanov V. A, Murata S, Yoshikawa K

    Angewandte Chemie International Edition   Vol. 43 ( 18 ) page: 2378-2371   2004

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  130. Ascorbic acid induces a marked conformational change in long duplex DNA

    Y Yoshikawa, M Suzuki, N Chen, AA Zinchenko, S Murata, T Kanbe, T Nakai, H Oana, K Yoshikawa

    EUROPEAN JOURNAL OF BIOCHEMISTRY   Vol. 270 ( 14 ) page: 3101 - 3106   2003.7

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:BLACKWELL PUBLISHING LTD  

    Ascorbic acid is often regarded as an antioxidant in vivo , where it protects against cancer by scavenging DNA-damaging reactive oxygen species. However, the detailed mechanism of the action of ascorbic acid on genetic DNA is still unclear. We examined the effect of ascorbic acid on the higher-order structure of DNA through real-time observation by fluorescence microscopy. We found that ascorbic acid generates a pearling structure in single giant DNA molecules, with elongated and compact regions coexisting along a molecular chain. Results from electron microscopy and atomic force microscopy indicate that the compact regions assume a loosely packed conformation. A possible mechanism for the induction of this conformational change is discussed in relation to the interplay between the higher-order and second-order structures of DNA.

    DOI: 10.1046/j.1432-1033.2003.03699.x

    Web of Science

    Scopus

  131. Ascorbic acid induces a marked conformational change in long duplex DNA.

    Yoshikawa Y, Suzuki M, Chen N, Zinchenko AA, Murata S, Kanbe T, Nakai T, Oana H, Yoshikawa K

    European journal of biochemistry   Vol. 270 ( 14 ) page: 3101-6   2003.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  132. Ascorbic acid induces a marked conformational change in long duplex DNA Reviewed

    Yoshikawa Y, Suzuki M, Chen N, Zinchenko A. A, Murata S, Kanbe T, Nakai T, Oana H, Yoshikawa K

    European Journal of Biochemistry   Vol. 270 ( 14 ) page: 3101-3106   2003

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    Language:English   Publishing type:Research paper (scientific journal)  

  133. Controlling the Intrachain Segregation on a Single DNA Molecule Reviewed

    Zinchenko A. A., Sergeyev V. G., Murata S., Yoshikawa K.

    J. Am. Chem. Soc.   Vol. 125 ( 15 ) page: 4414 - 4415   2003

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  134. Mechanism of Interaction of DNA with Surfactants in Water-Alcohol Media and Structure of the Related Complexes Reviewed

    Sergeyev V. G., Pyshkina O. A., Zinchenko A. A., Zezin S. B., Zezin A. B., Kabanov V. A.

    Polymer Science, Seriya A   Vol. 45 ( 5 ) page: 814 - 822   2003

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    Language:English   Publishing type:Research paper (scientific journal)  

  135. Ascorbic acid induces a marked conformational change in long duplex DNA Reviewed

    Yoshikawa Y., Suzuki M., Chen N., Zinchenko A. A., Murata S., Kanbe T., Nakai T., Oana H., Yoshikawa K.

    European Journal of Biochemistry   Vol. 270 ( 14 ) page: 3101-3106   2003

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    Language:English   Publishing type:Research paper (scientific journal)  

  136. Controlling the Intrachain Segregation on a Single DNA Molecule Reviewed

    Zinchenko A. A, Sergeyev V. G, Murata S, Yoshikawa K

    J. Am. Chem. Soc.   Vol. 125 ( 15 ) page: 4414 - 4415   2003

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    Language:English   Publishing type:Research paper (scientific journal)  

  137. Mechanism of Interaction of DNA with Surfactants in Water-Alcohol Media and Structure of the Related Complexes Reviewed

    Sergeyev V. G, Pyshkina O. A, Zinchenko A. A, Zezin S. B, Zezin A. B, Kabanov V. A

    Polymer Science, Seriya A   Vol. 45 ( 5 ) page: 814 - 822   2003

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    Language:English   Publishing type:Research paper (scientific journal)  

  138. Secondary Structure of DNA is Recognized by Slightly Cross-Linked Cationic Hydrogel Reviewed

    Sergeyev V. G., Novoskoltseva O. A., Zinchenko O. A., Pyshkina O. A, Rogacheva V. B., Zezin A. B., Yoshikawa K., Kabanov V. A.

    J. Am. Chem. Soc.   Vol. 124   page: 11324-11333   2002

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    Language:English   Publishing type:Research paper (scientific journal)  

  139. Secondary Structure of DNA is Recognized by Slightly Cross-Linked Cationic Hydrogel Reviewed

    Sergeyev V. G, Novoskoltseva O. A, Zinchenko O. A, Pyshkina O. A, Rogacheva V. B, Zezin A. B, Yoshikawa K, Kabanov V. A

    J. Am. Chem. Soc.   Vol. 124   page: 11324-11333   2002

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    Language:English   Publishing type:Research paper (scientific journal)  

  140. The secondary structure determines the character of DNA interaction with a slightly cross-linked cationic hydrogel Reviewed

    Sergeyev V. G., Novoskoltseva O. A., Zinchenko A. A., Pyshkina O. A, Rogacheva V. B., Zezin A. B., Kabanov V. A.

    Doklady Physical Chemistry   Vol. 116   page: 218-222   2001

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    Language:English   Publishing type:Research paper (scientific journal)  

  141. The secondary structure determines the character of DNA interaction with a slightly cross-linked cationic hydrogel Reviewed

    Sergeyev V. G, Novoskoltseva O. A, Zinchenko A. A, Pyshkina O. A, Rogacheva V. B, Zezin A. B, Kabanov V. A

    Doklady Physical Chemistry   Vol. 116   page: 218-222   2001

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    Language:English   Publishing type:Research paper (scientific journal)  

  142. DNA-surfactant complexes in a water/alcohol mixture Reviewed

    Zinchenko A. A., Sergeyev V. G., Pyshkina O. A.

    Progress in Polymer and Colloid Science   Vol. 116   page: 21-25   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

  143. Interpolyelectrolyte Complexes Formed by DNA and Astramol TM Poly(propyleneimine) Dendrimers Reviewed

    Kabanov V. A., Sergeyev V. G., Pyshkina, O. A. Zinchenko A. A., Zezin A. B, Joosten J. G. H., Brackman J., Yoshikawa K.

    Macromolecules   Vol. 33 ( 26 ) page: 9587-9593   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

  144. Interplay between Folding/Unfolding and Helix/Coil Transitions in Giant DNA Reviewed

    Mikhailenko S. V., Sergeyev V. G., Zinchenko A. A., Gallyamov M. O., Yaminsky I. V., Yoshikawa K.

    Biomacromolecules   Vol. 1 ( 4 ) page: 597-603   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

  145. DNA-surfactant complexes in a water/alcohol mixture Reviewed

    Zinchenko A. A, Sergeyev V. G, Pyshkina O. A

    Progress in Polymer and Colloid Science   Vol. 116   page: 21-25   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

  146. Interplay between Folding/Unfolding and Helix/Coil Transitions in Giant DNA Reviewed

    Mikhailenko S. V, Sergeyev V. G, Zinchenko A. A, Gallyamov M. O, Yaminsky I. V, Yoshikawa K

    Biomacromolecules   Vol. 1 ( 4 ) page: 597-603   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

  147. Interpolyelectrolyte Complexes Formed by DNA and Astramol TM Poly(propyleneimine) Dendrimers Reviewed

    Kabanov V. A, Sergeyev V. G, Pyshkina, O. A. Zinchenko A. A, Zezin A. B, Joosten J. G. H, Brackman J, Yoshikawa K

    Macromolecules   Vol. 33 ( 26 ) page: 9587-9593   2000

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 4

  1. 相分離生物学の全貌

    湊元 幹太, ジンチェンコ アナトーリ( Role: Joint author)

    東京化学同人  2020.11  ( ISBN:9784807913466

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    Language:Japanese Book type:Dictionary, encyclopedia

  2. リアルタイム計測による生命現象の解析 (R&D SERIES)・バイオ世界における自己組織化を利用したナノ構造・鋳型技術の進展

    ジンチェンコ アナトーリ, 鎌田宏幸( Role: Joint author)

    シーエムシー出版  2011.3 

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    Responsible for pages:127-134   Language:Japanese Book type:Dictionary, encyclopedia

  3. "Single DNA molecules: Compaction and decompaction" in DNA Interactions with Polymers and Surfactants, ed. Dias R.

    Zinchenko A. A., Pyshkina O. A., Lezov A. V., Sergeyev V. G., Yoshikawa K.( Role: Joint author)

    Willey-VCH  2008 

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    Language:English

    In this chapter we overview studies dedicated to the compaction of DNA by surfactants, multivalent cations and polymers, as well as decompaction, at single DNA molecule level.

  4. "Nanostructures and organizations of compacted single chains of polyelectrolytes" in Polymeric nanostructures and their applications

    Zinchenko A. A., Baigl D., Yoshikawa K.( Role: Joint author)

    American Scientific Publishers  2007 

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    Language:English

    In this chapter we describe how DNA molecule compaction approach can be used for preparation of well defined nanostructures. This review includes over 250 references on the procedures of DNA compaction and the nanostructures formation.

Presentations 27

  1. バイオマス由来の高分子材料の混合が地盤材料の変形・強度特性に及ぼす影響 International conference

    酒井崇之, 中野正樹, ジンチェンコアナトーリ

    令和2年度土木学会中部支部研究発表会  2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  2. DNA-Chitosan Hydrogels for Environmental and Materials Science Applications International conference

    K. Morikawa, A. Zinchenko

    5th Green and Sustainable Chemistry Conference  2020.11.11  Elsevier

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    Event date: 2020.11.10 - 2020.11.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  3. Preparation of complex gel from DNA and chitosan and its application as metal ion adsorption material

    Morikawa K., Zinchenko A.

    The 100th CSJ Annual Meeting 

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    Event date: 2020.3.22 - 2020.3.25

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  4. Compaction of DNA and Chromatin under Influence of Neutral and Anionic Crowding Invited International conference

    Zinchenko A.

    Okinawa Colloids 2019 

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    Event date: 2019.11.3 - 2019.11.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Okinawa, Japan   Country:Japan  

  5. Encapsulation of Long DNA into Polyelectrolyte Capsules International conference

    Zinchenko A., Inagaki E., Murata S.

    The 45th International Symposium on Nucleic Acids Chemistry 

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    Event date: 2018.11.7 - 2018.11.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  6. Unimolecular compaction of megabase-long chromatin International conference

    Zinchenko A.

    Workshop on Polyelectrolytes in Chemistry, Biology and Technology 2018 

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    Event date: 2018.3.12 - 2018.3.14

    Language:English   Presentation type:Oral presentation (general)  

    Country:Singapore  

  7. Application of DNA-Based Hydrogels and Multilayered Films for Templating of Inorganic Nanomaterials Invited International conference

    Zinchenko A.

    International Symposium on Polyelectrolytes 

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    Event date: 2016.6.30 - 2016.7.2

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Russian Federation  

  8. Novel Applications of DNA in Fields of Environment and Nanomaterials

    Zinchenko A. A.

    International Symposium on EcoTopia Science 2011  

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    Event date: 2011.12.9 - 2011.12.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  9. DNAを用いた二重鋳型法による中空ナノシェル構造創製 International conference

    ジンチェンコ アナトーリ,蒲生彦,村田静昭

    ナノ学会第9回大会 

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    Event date: 2011.6.2 - 2011.6.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  10. DNA スポンジを用いた水溶液中からの重金属イオン除去

    松岡紗緒里・酒井博臣・Zinchenko Anatoly・村田静昭

    第40中部化学関係学協会支部連合秋季大会 

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    Event date: 2009.11.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  11. Study on Interaction of DNA with Chiral Nanoparticles to Verify a Role of Molecular Chirality of Nanoscale Template in DNA Compaction International conference

    International Conference on Nanoscience and Technology "China Nano" 2009 

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    Event date: 2009.9.2

    Language:English   Presentation type:Poster presentation  

  12. 単一分子DNA金属化によりDNAー金属ナノ構造体の形成

    Zinchenko, Anatoly・陳 寧・Baigl, Damien・吉川 研一

    第89日本化学会第89春季年会 

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    Event date: 2009.3.29

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  13. Detection of Polymer Conformational Transition by Metallization with Noble Metals

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    Event date: 2008.11.9

    Language:English   Presentation type:Oral presentation (general)  

  14. Purification of Heavy Metal Ions from Aqueous Solutions by Incorporation into DNA-Surfactant Complexes International conference

    5th International Conference "Interfaces Against Pollution" (IAP 2008) 

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    Event date: 2008.6.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  15. A novel type cationic silica nanoparticles and its potential application in biomedicine

    Liu L.

    2nd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2008 

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    Event date: 2008.1.1

    Language:English   Presentation type:Oral presentation (general)  

    Scopus

  16. DNA-nanoparticles complexes as a simplest chromatin model

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    Event date: 2007.11.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    ジンチェンコ アナトーリ

  17. Biomimetic DNA compaction by cationic nanoparticles International conference

    American Chemical Society 231st National Meeting and Exposition 

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    Event date: 2006.3.27

    Language:English   Presentation type:Oral presentation (general)  

  18. Compaction of Single-Chain DNA by Histone-Inspired Nanoparticles International conference

    European Polymer Congress 

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    Event date: 2005.6.27

    Language:English   Presentation type:Oral presentation (invited, special)  

  19. Compaction of DNA and Chromatin under Influence of Neutral and Anionic Crowding Invited

    Zinchenko A

    Okinawa Colloids 2019  2019.11.3 

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    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Okinawa, Japan  

  20. A novel type cationic silica nanoparticles and its potential application in biomedicine International conference

    Liu L

    2nd International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2008  2008.1.1 

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    Language:English   Presentation type:Oral presentation (general)  

  21. Application of DNA-Based Hydrogels and Multilayered Films for Templating of Inorganic Nanomaterials Invited

    Zinchenko A

    International Symposium on Polyelectrolytes  2016.6.30 

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    Language:English   Presentation type:Oral presentation (invited, special)  

  22. DNA-Chitosan Hydrogels for Environmental and Materials Science Applications

    K. Morikawa, A. Zinchenko

    5th Green and Sustainable Chemistry Conference  2020.11.10 

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    Language:English   Presentation type:Poster presentation  

  23. DNAを用いた二重鋳型法による中空ナノシェル構造創製

    ジンチェンコ アナトーリ, 蒲生彦, 村田静昭

    ナノ学会第9回大会  2011.6.2 

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    Language:Japanese   Presentation type:Oral presentation (general)  

  24. Encapsulation of Long DNA into Polyelectrolyte Capsules

    Zinchenko A, Inagaki E, Murata S

    The 45th International Symposium on Nucleic Acids Chemistry  2018.11.7 

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    Language:English   Presentation type:Oral presentation (general)  

  25. Novel Applications of DNA in Fields of Environment and Nanomaterials International conference

    Zinchenko A. A

    International Symposium on EcoTopia Science 2011  2011.12.9 

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    Language:English   Presentation type:Oral presentation (invited, special)  

  26. Preparation of complex gel from DNA and chitosan and its application as metal ion adsorption material International conference

    Morikawa K, Zinchenko A

    The 100th CSJ Annual Meeting  2020.3.22 

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    Language:English   Presentation type:Poster presentation  

  27. Unimolecular compaction of megabase-long chromatin

    Zinchenko A

    Workshop on Polyelectrolytes in Chemistry, Biology and Technology 2018  2018.3.12 

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    Language:English   Presentation type:Oral presentation (general)  

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KAKENHI (Grants-in-Aid for Scientific Research) 5

  1. DNA conformational behavior and functions in microcapsules

    Grant number:17K05611  2017.04 - 2020.03

    Zinchenko Anatoly

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    In eukaryotic cells, DNA macromolecules with a length exceeding 1 meter are densely folded and exist in cells with a size of several μm. Artificial experimental models are needed to explain the higher order structure and behavior of DNA in cellular-like environment. In this study, we constructed an "artificial cell model" method for encapsulating very ling genomic DNA in polymer capsules of several μm size. Using this experimental model, we made clear the behavior of DNA confined in the cell-sized space. The experimental methodology proposed in this study is promising for gene delivery and related biomedical applications.

  2. Construction of 2- and 3-dimensional nanostructures using DNA metallization

    Grant number:24710106  2012.04 - 2015.03

    ZINCHENKO Anatoly

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

    DNA extracted from salmon milt, the waste product of marine industry, was utilized as a functional material for construction of 2- and 3-dimensional nanomaterials for catalytic applications. DNA-based thin polymeric films and DNA hydrogels were first prepared and then used for efficient adsorption of noble metals (Au, Ag, Pt, Pg, etc.). After adsorption of metal ions inside DNA-based material, reduction of metal ions inside thin film/hydrogel resulted in a formation of well dispersed metal nanoparticles of several nanometer sizes with a narrow size distributions. Thus prepared hybrid materials showed high catalytic activity that can be controlled by swelling/shrinking of hydrogel matrix. In contrast to colloidal solutions of catalytic nanoparticles which separation and recovery problems limit their applications, DNA-based catalysts developed in this project are advantageous due to high stability, facile operation during catalysis, easy separation form reaction mixtures and reuse.

  3. ゲノムDNAのナノテンプレートによる構造と機能の制御

    Grant number:20034025  2008 - 2010

    ZINCHENKO A.A.

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2900000 ( Direct Cost: \2900000 )

    本研究では、様々なナノテンプレート(ナノメーターサイズ物質)を用いて、DNAとの相互作用および形成されるコンプレックスの形態をプログラミングすることに、DNA高次構造と機能の制御を目的としたものである。本年度、球状テンプレート(シリカナノ粒子)および棒状テンプレート(金ナノロッド)はDNA二次構造と高次構造に与える影響について研究した。(1) DNAの溶液中安定性およびDNA二次構造(二重らせん)の安定性に対するナノ粒子の影響を調べた。アニオン性ナノ粒子の影響はなかったが、カチオン性ナノ粒子はDNAの溶液中安定性を乱し、DNAの沈殿を起こし、更に、DNAを沈殿させないナノ粒子の濃度においても、DNAの二重らせんが高くなると連れて、DNA二重らせんの溶解は大きく抑制された。この結果から、自然界で起こるDNAの二重らせん溶解が必要な過程(転写、複製)では、カチオン性ナノ粒子がこのような過程を妨げると考えられる。(2) 次は、DNAとナノ粒子の間の相互作用における生物学的に重要な一価と二価カチオンの影響について研究した。その結果は、全てのカチオンがナノ粒子によってDNA凝縮を促進し、Na^+とK^+またはMg^<2+>とCa^<2+>の間は大直径のカチオンの効果が高かった。(3) 最後に、DNAとカチオン性ナノロッドの間相互作用を徹底的に調べ、ナノロッド濃度によって様々なDNA-ナノロッド複合体のナノ構造を観察行った。カチオン性ナノロッドはDNA凝縮を誘起することにより、DNA鎖上のナノロッドが自己組織化する。DNA対ナノロッドの割合によって、DNA鋳型に沿うって並んでおり、ナノロードの高濃度においてはDNAが凝縮しながら、DNAとコンプレックスしたナノロッドが高秩序構造(結晶状の構造)に組織化することを明らかにした。

  4. 時空間秩序の自己組織と生命現象化

    2007.01 - 2011.03

    科学研究費補助金  国際共同研究事業(ICORP),科学技術振興機構

    吉川 研一

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    Authorship:Other 

  5. Long chain DNA folding by nanoparticles: Construction of Artificial Chromatin Model

    Grant number:18719001  2006 - 2008

    ZINCHENKO A.a.

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3740000 ( Direct Cost: \3500000 、 Indirect Cost:\240000 )

Industrial property rights 1

  1. 粒子材料及びその製造方法

    村田静昭, ジンチェンコ アナトーリ, 蒲生彦

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    Application no:特願 2010-234833  Date applied:2010.10.19

    Country of applicant:1  

 

Teaching Experience (On-campus) 13

  1. Sustainability and Environmental Studies

    2020

  2. 環境物質学5

    2018

  3. 化学基礎I

    2018

  4. ナノテクノロジーと環境

    2018

  5. 環境物質学実験 2

    2018

  6. 環境物質学5

    2017

  7. ナノテクノロジーと環境

    2017

  8. 化学基礎I

    2017

  9. 環境物質学実験 2

    2017

  10. Laboratory in Chemistry

    2011

  11. 環境ナノテクノロジー

    2009

  12. 化学実験

    2009

  13. 環境物質5

    2009

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Media Coverage 1

  1. 化学グランプリ(作題・実行)

    日本化学会  2014.9