Updated on 2024/03/13

写真a

 
MATSUSHIMA, Masaya
 
Organization
Nagoya University Hospital Radiology Lecturer of hospital
Title
Lecturer of hospital

Degree 1

  1. 博士(医学) ( 2010.9   名古屋大学 ) 

 

Papers 17

  1. “Speckled Enhancement” on Gd-EOB-DTPA Enhanced MR Imaging of Primary Hepatic Mucosa-associated Lymphoid Tissue Lymphoma

    Hyodo Ryota, Takehara Yasuo, Nishida Ayumi, Matsushima Masaya, Naganawa Shinji

    Magnetic Resonance in Medical Sciences   Vol. 22 ( 3 ) page: 273 - 281   2023

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    Language:English   Publisher:Japanese Society for Magnetic Resonance in Medicine  

    <p>Purpose: To elucidate MRI features of primary hepatic mucosa-associated lymphoid tissue (MALT) lymphoma, particularly, the “speckled enhancement” on gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MRI.</p><p>Methods: The institutional review board approved this retrospective observational study and waived informed consent. Using our picture archiving and communication systems and electronic medical records, five patients histopathologically diagnosed as hepatic MALT lymphoma and clinically confirmed as primary lesions who had undergone dynamic contrast-enhanced (DCE)-CT and DCE-MRI with Gd-EOB-DTPA were identified from September 2009 to December 2020. Two radiologists assessed their CT and MRI data in consensus with a pathologist’s advice.</p><p>Results: Overall, five lesions in five patients were included in this study. Precontrast CT showed hypoattenuation in all lesions. In the arterial phase of DCE-CT, four lesions (80%) showed hyperattenuation, whereas all lesions showed iso- to hypoattenuation in the delayed phase. A vessel penetration sign was also observed in all lesions. On MRI, all lesions showed hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and restricted diffusion on diffusion-weighted images. Both DCE-CT and DCE-MRI with Gd-EOB-DTPA showed similar enhancement patterns, except for the hepatocyte phase. Notably, however, four out of five lesions showed characteristic “speckled enhancement” that refers to punctate positive enhancements within the low signal lesions on the hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI pathologically confirmed to be hepatocyte clusters that remained in the tumor.</p><p>Conclusion: Primary hepatic MALT lymphomas were characterized by arterial phase enhancement, restricted diffusion, vessel penetration sign, and more specifically “speckled enhancement” in the hepatobiliary phase of DCE-MRI with Gd-EOB-DTPA.</p>

    DOI: 10.2463/mrms.mp.2021-0069

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  2. Embolization using patient-specific vascular models created by a 3D printer for difficult cases: a report of two cases

    Komada, T; Kamomae, T; Matsushima, M; Hyodo, R; Naganawa, S

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 2 ) page: 477 - 483   2022.5

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    Language:English   Publisher:Nagoya Journal of Medical Science  

    With the widespread use of three-dimensional printers, organ models created by these printers are now being used in the medical field for preoperative planning of surgeries. In this article, we report two cases in which embolization was expected to be difficult, and the three-dimensional printer-based vascular modeling was helpful in planning the surgery. The first case involved an aneurysm of the splenic artery. We attempted to embolize the aneurysm but were unable to advance the catheter into the distal artery and discontinued the procedure. The second case was a perianal varicose vein, which was initially treated with percutaneous transhepatic obliteration but was recanalized and required embolization. However, we expected difficulty in selecting the inferior mesenteric vein. In both cases, the vascular models were created using a 3D printer from the patients’ computed tomography images. Preoperative planning, including treatment simulation, was based on these models. The time required to print a three-dimensional vascular model was approximately 12 hours at a cost of less than $10 each. Patient-specific vascular models using a three-dimensional printer can be a simple and inexpensive tool that can increase the success of embolization in difficult cases.

    DOI: 10.18999/nagjms.84.2.477

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  3. A case of stent-graft implantation for postpancreaticoduodenectomy hemorrhage in a patient with a reconstructed gastric tube.

    Komada T, Tachi Y, Nagasaka K, Yamada S, Matsushima M, Sakaki Y, Naganawa S

    Radiology case reports   Vol. 15 ( 12 ) page: 2710 - 2713   2020.12

  4. Evaluation of segment 4 portal vein embolization added to right portal vein for right hepatic trisectionectomy: A retrospective propensity score-matched study

    Ito, J; Komada, T; Suzuki, K; Matsushima, M; Nakatochi, M; Kobayashi, Y; Ebata, T; Naganawa, S; Nagino, M

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 27 ( 6 ) page: 299 - 306   2020.6

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    Language:English   Publisher:Journal of Hepato-Biliary-Pancreatic Sciences  

    Background: Adding segment 4 (S4) portal vein embolization (PVE) to right PVE before right hepatic trisectionectomy is controversial. We retrospectively examined the effect of S4 PVE on segments 2 and 3 (S2 + 3) hypertrophy. Methods: We reviewed patients with biliary carcinoma who underwent right PVE with (R3PVE) or without (R2PVE) S4 PVE using gelatin sponge particles and coils (2010-2019). Propensity score matching balanced the cohort for baseline characteristics, including total liver volume and S2 + 3 volume before PVE. We compared the groups regarding the S2 + 3 volume changes after PVE. Results: Of 178 enrolled patients, 38 underwent R3PVE for right hepatic trisectionectomy and 140 underwent R2PVE for right hepatectomy. Twenty-eight patients from each group were respectively matched. The median absolute volume increase in (146 cm3 vs 70 cm3), hypertrophy rate of (52.4% vs 32.3%), and kinetic growth rate of (3.1%/wk vs 2.0%/wk) S2 + 3 were significantly higher in the R3PVE group than in the R2PVE group. In the pre-matched cohort, the rate of posthepatectomy liver failure and postoperative hospital stay did not significantly differ between the patients who underwent right hepatic trisectionectomy and right hepatectomy. Conclusion: R3PVE increased the S2 + 3 volume more effectively than R2PVE in patients with biliary carcinoma.

    DOI: 10.1002/jhbp.723

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  5. Balloon-Occluded Retrograde Transvenous Obliteration for Fundal Gastric Variceal Bleeding in a Small Child

    Komada, T; Suzuki, K; Oshima, K; Matsushima, M; Nagasaka, K; Naganawa, S

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY   Vol. 30 ( 10 ) page: 1624 - 1625   2019.10

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    Language:English   Publisher:Journal of Vascular and Interventional Radiology  

    DOI: 10.1016/j.jvir.2019.06.022

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  6. 画像診断と病理 腎静脈に発生した平滑筋肉腫

    松島 正哉, 林 葉子, 岩野 信吾, 長縄 慎二, 下山 芳江

    画像診断   Vol. 39 ( 3 ) page: 252 - 253   2019.2

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    Publisher:学研メディカル秀潤社  

    DOI: 10.15105/gz.0000000981

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  7. Successful treatment of esophageal bleeding due to rupture of major aortopulmonary collateral arteries by transcatheter arterial embolization

    Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Matsushima Masaya, Kato Taichi, Hirooka Yoshiki

    CLINICAL JOURNAL OF GASTROENTEROLOGY   Vol. 12 ( 1 ) page: 20-24   2019.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s12328-018-0895-8

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  8. Efficacy of percutaneous transhepatic portal vein embolization using gelatin sponge particles and metal coils

    Komada Tomohiro, Suzuki Kojiro, Mizuno Takashi, Ebata Tomoki, Matsushima Masaya, Naganawa Shinji, Nagino Masato

    ACTA RADIOLOGICA OPEN   Vol. 7 ( 4 ) page: 2058460118769687   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1177/2058460118769687

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  9. A Surviving Case of Abdominal Compartment Syndrome Following Embolization for Massive Bleeding From the Inferior Pancreaticoduodenal Artery With Hemorrhagic Shock

    Suzuki Yumi, Saeki Satomi, Matsushima Masaya, Hiramatsu Kiyoshi, Arai Toshiyuki

    Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine)   Vol. 38 ( 1 ) page: 105 - 108   2018.1

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    Language:Japanese   Publisher:Japanese Society for Abdominal Emergency Medicine  

    <p>We report hereon on a rare case of a 72-year-old female with abdominal compartment syndrome (ACS) following embolization for massive bleeding from the inferior pancreaticoduodenal artery who was saved by open abdominal surgery. She came to our hospital by ambulance diagnosed as having massive bleeding from the retroperitoneal vasculature and she was in a state of severe hemorrhagic shock. Angiography revealed that the extravasation was from the inferior pancreaticoduodenal artery and we performed embolization of the artery. After the embolization, she had ACS and we quickly performed open abdominal surgery to remove a large hematoma from her abdomen. After the operation, she recovered. As we can stop bleeding quickly, embolization is an effective treatment for arterial hemorrhage shock. On the other hand there is so a big risk for the occurrence of ACS, as a large amount of hematoma could be left in the abdomen. It is important that we recognize the risk for ACS after embolization for massive bleeding.</p>

    DOI: 10.11231/jaem.38.105

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  10. Portal Vein Bleeding after Pancreatectomy: Diagnosis and Stent Graft Repair - A Consecutive Case Series

    Suzuki Kojiro, Ebata Tomoki, Komada Tomohiro, Matsushima Masaya, Mizuno Takashi, Igami Tsuyoshi, Sugawara Gen, Yokoyama Yukihiro, Naganawa Shinji, Nagino Masato

    JOURNAL OF THE PANCREAS   Vol. 18 ( 4 ) page: 339-344   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

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  11. Ex-vivo ultra-high-resolution optical coherence tomography imaging of fine lung structure by use of a high-power Gaussian-like supercontinuum at 0.8-um wavelength.

    Nishizawa N., Ishida S., Ohta T., Itoh K., Kitatsuji M., Ohshima H., Hasegawa Y., Matsushima M., Kawabe T.

    ENDOSCOPIC MICROSCOPY VI   Vol. 7893   2011

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    Publisher:Progress in Biomedical Optics and Imaging - Proceedings of SPIE  

    Optical coherence tomography (OCT) is an emerging technology for non-invasive cross-sectional imaging of biological tissue and material with um resolution. Recently, non-invasive high resolution cross-sectional imaging is desired for investigation of diseases in lung in the field of pulmonary medicine. So far, a few works have been reported about OCT imaging of lung. Since the lung consists of alveoli separated by thin wall, ultrahigh resolution (UHR) OCT is supposed to be effective for the imaging of fine structure in lung tissue. In this work, ex vivo cross-sectional imaging of isolated rat lungs was demonstrated using UHR-OCT. A 120 nm-wide, high-power, Gaussian-like supercontinuum (SC) was generated at wavelength of 0.8 um region and it was used as the light source in time domain UHR-OCT. An ultrahigh resolution of 2.1 um in tissue was obtained and the achieved sensitivity was 105 dB. For the UHR-OCT imaging of trachea, the detailed structures of the tracheal cartilage and tracheal mucosa overlying the cartilage were observed clearly. The epithelium and lamina propria were also distinguishable. For the imaging of visceral pleura and alveoli, when saline was instilled into the lung, the penetration depth was improved, and clear images of the fine structure of the lung, including alveoli, were observed owing to the index matching effect. The clear images of up to about 4 alveoli were observed below the visceral pleura. The shape of the alveolar septum was clearly observed, and the alveolar sac was clearly visible. © 2011 SPIE.

    DOI: 10.1117/12.878874

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  12. Diagnostic Value of SPIO-mediated Breath-hold, Black-blood, Fluid-attenuated, Inversion Recovery (BH-BB-FLAIR) Imaging in Patients with Hepatocellular Carcinomas

    MATSUSHIMA Masaya, NAGANAWA Shinji, IKEDA Mitsuru, ITOH Shigeki, OGAWA Hiroshi, KOMADA Tomohiro, ISHIGAKI Satoko, KAWAI Hisashi, SUZUKI Koujiro, SATAKE Hiroko, IWANO Shingo

    Magnetic Resonance in Medical Sciences   Vol. 9 ( 2 ) page: 49 - 58   2010

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    Language:English   Publisher:Japanese Society for Magnetic Resonance in Medicine  

    Purpose: We assessed the value of adding a breath-hold, black-blood, fluid-attenuated, inversion recovery (BH-BB-FLAIR) sequence with a small motion-probing gradient (b=10 s/mm<sup>2</sup>) using superparamagnetic iron oxide (SPIO) to our present studies that utilize SPIO to detect hepatocellular carcinoma (HCC). We used inversion recovery (IR) in a FLAIR sequence to suppress signals from cysts and a low b-value to suppress vessel signals and provide higher signal to noise than that using high b-value diffusion-weighted imaging. Use of SPIO is expected to reduce the signal in both normal liver parenchyma and in most benign lesions.<br> Materials and Methods: In 19 patients, we reviewed 38 HCC nodules diagnosed by CT arterioportography (CTAP) and CT during hepatic arteriography (CTHA). We divided SPIO-mediated images into sets, those obtained with and without BH-BB-FLAIR. Six radiologists individually interpreted the 2 image sets and sorted them by their confidence levels for the presence of HCC, and we calculated the area under the receiver operating characteristic (ROC) curve (Az) for each image set.<br> Results: On images obtained with BH-BB-FLAIR after SPIO administration, 33 of the 38 HCC nodules appeared as areas of high signal and cyst signal was extinguished. The ROC analysis showed significantly higher Az values in the set with BH-BB-FLAIR (0.89) than in the set without (0.83).<br> Conclusions: Adding BH-BB-FLAIR to existing SPIO-mediated imaging protocols improved detection of HCC nodules and added only 24 s to the scan time.<br>

    DOI: 10.2463/mrms.9.49

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  13. Diagnosis of periampullary region with a multislice CT scanner

    ITOH Shigeki, MATUSHIMA Masaya, SUZUKI Kojiro, OTA Toyohiro, NAGANAWA Shinji

      Vol. 23 ( 5 ) page: 806 - 815   2009.12

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    Language:Japanese  

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  14. Diagnosis of periampullary region with a multislice CT scanner

    Itoh Shigeki, Matushima Masaya, Suzuki Kojiro, Ota Toyohiro, Naganawa Shinji

    Tando   Vol. 23 ( 5 ) page: 806 - 815   2009

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    Language:Japanese   Publisher:Japan Biliary Association  

    For CT diagnosis of the periampullary region, it is essential to perform multiphase contrast-enhanced examinations with collimation of 1.25 mm or less and reconstruct axial images as well as high-resolution multiplanar reformatted images with a 2-3-mm slice thickness. These images make it possible to depict small anatomic structures such as the pancreatic and intrapancreatic bile ducts and pancreaticoduodenal arterial arcade. Furthermore, the examinations permit the visualization of the area showing less contrast enhancement between the pancreatic head and duodenum in pancreatic-phase images, what is assumed to correspond to the area of the ducts surrounded by the sphincter of Oddi. In the patients with ampullary neoplasms presenting with dilatation of the pancreatic and/or bile ducts, the most valuable role required for CT is to determine the absence of other disorders such as pancreatic cancer and bile duct cancer. However, since it is impossible to identify the common channel, the muscularis propria of the duodenal wall, and the sphincter of Oddi on CT, the role in local staging of ampullary tumor is limited. Since ampullary tumors have a relatively good prognosis, it is also required to pay enough attention to side effects associated with radiation exposure and contrast media in CT examinations.<br>

    DOI: 10.11210/tando.23.806

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  15. Endovascular Management of Ruptured Pancreaticoduodenal Artery Aneurysms Associated with Celiac Axis Stenosis

    Suzuki, K; Tachi, Y; Ito, S; Maruyama, K; Mori, Y; Komada, T; Matsushima, M; Ota, T; Naganawa, S

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY   Vol. 31 ( 6 ) page: 1082 - 1087   2008.11

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    Language:English   Publisher:CardioVascular and Interventional Radiology  

    The purpose of this study was to assess the efficacy of transcatheter arterial embolization for ruptured pancreaticoduodenal artery (PDA) aneurysms associated with celiac axis stenosis (CS). Seven patients (four men and three women; mean age, 64; range, 43-84) were treated with transcatheter arterial embolization between 2002 and 2007. They were analyzed with regard to the clinical presentation, radiological finding, procedure, and outcome. All patients presented with sudden epigastric pain or abdominal discomfort. Contrast-enhanced CT showed a small aneurysm and retroperitoneal hematoma around the pancreatic head in all patients. The aneurysms ranged from 0.3 to 0.9 cm in size. In one patient, two aneurysms were detected. The aneurysms were located in the pancreaticoduodenal artery (n = 5) and the dorsal pancreatic artery (n = 3). Embolization was performed with microcoils in all aneurysms (n = 8). N-Butyl 2-cyanoacrylate (n = 1) and gelatine particle (n = 1) were also used. Complete occlusion was achieved in four patients. In the other three patients, a significantly reduced flow to the aneurysm remained at final angiography. However, these aneurysms were thrombosed on follow-up CT within 2 weeks. And there was no recurrence of the symptoms and bleeding during follow-up (mean, 28 months; range, 5-65 months) in all patients. In conclusion, transcatheter arterial embolization for PDA aneurysms associated with CS is effective. Significant reduction of the flow to the aneurysm at final angiography may be predictive of future thrombosis. © 2008 Springer Science+Business Media, LLC.

    DOI: 10.1007/s00270-008-9343-3

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  16. Contrast-enhanced MR Imaging of Metastatic Brain Tumor at 3 Tesla: Utility of T1-weighted SPACE Compared with 2D Spin Echo and 3D Gradient Echo Sequence

    KOMADA Tomohiro, NAGANAWA Shinji, OGAWA Hiroshi, MATSUSHIMA Masaya, KUBOTA Seiji, KAWAI Hisashi, FUKATSU Hiroshi, IKEDA Mitsuru, KAWAMURA Minako, SAKURAI Yasuo, MARUYAMA Katsuya

    Magnetic Resonance in Medical Sciences   Vol. 7 ( 1 ) page: 13 - 21   2008

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    We evaluated the newly developed whole-brain, isotropic, 3-dimensional turbo spin-echo imaging with variable flip angle echo train (SPACE) for contrast-enhanced T<sub>1</sub>-weighted imaging in detecting brain metastases at 3 tesla (T). Twenty-two patients with suspected brain metastases underwent postcontrast study with SPACE, magnetization-prepared rapid gradient-echo (MP-RAGE), and 2-dimensional T<sub>1</sub>-weighted spin echo (2D-SE) imaging at 3T. We quantitatively compared SPACE, MP-RAGE, and 2D-SE images by using signal-to-noise ratios (SNRs) for gray matter (GM) and white matter (WM) and contrast-to-noise ratios (CNRs) for GM-to-WM, lesion-to-GM, and lesion-to-WM. Two blinded radiologists evaluated the detection of brain metastases by segment-by-segment analysis and continuously-distributed test. The CNR between GM and WM was significantly higher on MP-RAGE images than on SPACE images (<i>P</i><0.01). The CNRs for lesion-to-GM and lesion-to-WM were significantly higher on SPACE images than on MP-RAGE images (<i>P</i><0.01). There was no significant difference in each sequence in detection of brain metastases by segment-by-segment analysis and the continuously-distributed test. However, in some cases, the lesions were easier to detect in SPACE images than in other sequences, and also the vascular signals, which sometimes mimic lesions in MP-RAGE and 2D-SE images, were suppressed in SPACE images. In detection of brain metastases at 3T magnetic resonance (MR) imaging, SPACE imaging may provide an effective, alternative approach to MP-RAGE imaging for 3D T<sub>1</sub>-weighted imaging.<br>

    DOI: 10.2463/mrms.7.13

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  17. Colocalization of adhesive contact and vesicles in the growth cones of PC12 cells

    Tatsumi H., Iwai K., Matsushima M., Inoue Y., Sokabe M.

    Seibutsu Butsuri   Vol. 40 ( supplement ) page: S14   2000

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    Language:Japanese   Publisher:The Biophysical Society of Japan General Incorporated Association  

    DOI: 10.2142/biophys.40.s14_1

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MISC 1

  1. A case of stent-graft implantation for postpancreaticoduodenectomy hemorrhage in a patient with a reconstructed gastric tube.

    Komada T, Tachi Y, Nagasaka K, Yamada S, Matsushima M, Sakaki Y, Naganawa S

    Radiology case reports   Vol. 15 ( 12 ) page: 2710 - 2713   2020.12

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    Language:English   Publisher:Radiology Case Reports  

    In patients with a reconstructed gastric tube, the right gastroepiploic artery is a very important feeding artery of the tube, which must be preserved when performing a pancreaticoduodenectomy. A 76-year-old man with a reconstructed gastric tube underwent pancreaticoduodenectomy for distal bile duct carcinoma. On postoperative day 8, he had an arterial hemorrhage from a drain, apparently from a ligation of the anterior superior duodenal artery. He, therefore, underwent stent-graft placement in the gastroduodenal artery. The stent-grafts were temporarily occluded, and the gastric tube was necrotizing. However, thrombolytic therapy allowed the stent-grafts to reopen and prevented gastric tube necrosis. We believe our case of stent-graft implantation in the gastroduodenal artery is the first of this kind to successfully prevent lethal necrosis of the gastric tube.

    DOI: 10.1016/j.radcr.2020.10.021

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KAKENHI (Grants-in-Aid for Scientific Research) 1

  1. A new strategy of IVR for extended hepatic resection incorporating evaluation of intrahepatic portal collateral tracts and hepatic vein embolization

    Grant number:21K07562  2021.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Coinvestigator(s)