研究者詳細 - 髙橋　義行

論文 - 髙橋　義行

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肺高血圧症(PH)をきたしtadalafilで治療した造血幹細胞移植(HSCT)後の3例

深澤佳絵, 早野聡, 沼口敦, 高橋義行, 加藤太一

日本小児循環器学会雑誌 33 巻 ( Suppl.1 ) 頁： s1 - 402 2017年7月

PiggyBac transposon, a non-viral gene transfer system, mediated T cells expressing CD19 chimeric antigen receptor for a 'first in human' clinical trial

Takahashi Y, Nishio N, Hamada M, Tanaka M, Morita D, Kawashima N, Okuno Y, Narita A, Muramatsu H, Hama A, Kojima S, Dotti G, Nakazawa Y

BONE MARROW TRANSPLANTATION 52 巻頁： S161-S162 2017年7月

RECURRENT MYB REARRANGEMENT IN BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM

Suzuki, K; Okuno, Y; Suzuki, Y; Hama, A; Muramatsu, H; Nakatochi, M; Gunji, M; Ichikawa, D; Hamada, M; Taniguchi, R; Kataoka, S; Murakami, N; Kojima, D; Sekiya, Y; Nishikawa, E; Kawashima, N; Narita, A; Nishio, N; Nakazawa, Y; Iwafuchi, H; Watanabe, K; Ito, M; Kojima, S; Kato, S; Takahashi, Y

HAEMATOLOGICA 102 巻頁： 35 - 35 2017年6月

Efficacy of neutrophil non-muscle myosin heavy chain-IIA immunofluorescence analysis in determining the pathogenicity of <i>MYH9</i> variants 査読有り国際誌

Kunishima, S; Yusuke, O; Muramatsu, H; Kojima, D; Nagai, N; Takahashi, Y; Kojima, S

ANNALS OF HEMATOLOGY 96 巻 ( 6 ) 頁： 1065 - 1066 2017年6月

Long-term outcomes of 95 children with moderate aplastic anemia treated with horse antithymocyte globulin and cyclosporine 査読有り国際誌

Nishikawa, E; Yagasaki, H; Hama, A; Yabe, H; Ohara, A; Kosaka, Y; Kudo, K; Kobayashi, R; Ohga, S; Morimoto, A; Watanabe, K; Yoshida, N; Muramatsu, H; Takahashi, Y; Kojima, S

PEDIATRIC BLOOD & CANCER 64 巻 ( 5 ) 2017年5月

Paroxysmal nonepileptic events in children with epilepsy 査読有り国際誌

Ito, Y; Kidokoro, H; Negoro, T; Tanaka, M; Okai, Y; Sakaguchi, Y; Ogawa, C; Takeuchi, T; Ohno, A; Yamamoto, H; Nakata, T; Maesawa, S; Watanabe, K; Takahashi, Y; Natsume, J

EPILEPSY RESEARCH 132 巻頁： 59 - 63 2017年5月

PiggyBac Mediated T Cells Expressing Anti CD19 Chimeric Antigen Receptor for a Clinical Trial

Nishio, N; Nakazawa, Y; Hamada, M; Suzuki, S; Tanaka, M; Morita, D; Kawashima, N; Okuno, Y; Narita, A; Hama, A; Muramatsu, H; Muramatsu, H; Kojima, S; Takahashi, Y

MOLECULAR THERAPY 25 巻 ( 5 ) 頁： 291 - 291 2017年5月

Germline IKAROS mutation associated with primary immunodeficiency that progressed to T-cell acute lymphoblastic leukemia 査読有り

Yoshida, N; Sakaguchi, H; Muramatsu, H; Okuno, Y; Song, C; Dovat, S; Shimada, A; Ozeki, M; Ohnishi, H; Teramoto, T; Fukao, T; Kondo, N; Takahashi, Y; Matsumoto, K; Kato, K; Kojima, S

LEUKEMIA 31 巻 ( 5 ) 頁： 1221 - 1223 2017年5月

Early germinal vesicle breakdown is a predictor of high preimplantation developmental competent oocytes in mice 査読有り

Shogo Higaki, Masao Kishi, Keisuke Koyama, Masashi Nagano, Seiji Katagiri, Tatsuyuki Takada, Yoshiyuki Takahashi

ZYGOTE 25 巻 ( 1 ) 頁： 41 - 48 2017年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：CAMBRIDGE UNIV PRESS

The preselection of highly developmentally competent oocytes for in vitro maturation (IVM) is crucial for improving assisted reproductive technology. Although several intrinsic markers of oocyte quality are known to be closely related to the onset of nuclear maturation (germinal vesicle break down, GVBD), a direct comparison between GVBD timing and oocyte quality has never been reported. In this study, we established a non-invasive oocyte evaluation method based on GVBD timing for preselecting more developmental competent oocytes in mice. Because the O-2 concentration during IVM may affect the nuclear kinetics, all experiments were performed under two distinct O-2 concentrations: 20% and 5% O-2. First, we determined the time course of changes in nuclear maturation and preimplantation developmental competence of in vitro-matured oocytes to estimate GVBD timing in high developmental competent oocytes. Two-thirds of oocytes that underwent GVBD in early IVM seemed to mainly contribute to the blastocyst yield. To confirm this result, we compared the preimplantation developmental competence of the early and late GVBD oocytes. Cleavage and blastocyst formation rates of early GVBD oocytes (80.2% and 52.7% under 20% O-2, respectively, and 67.6% and 47.3% under 5% O-2, respectively) were almost double those of late GVBD oocytes (44.8% and 26.0% under 20% O-2, respectively, and 40.4% and 17.9% under 5% O-2, respectively). With no observable alterations by checking the timing of GVBD in preimplantation developmental competence, oocyte evaluation based on GVBD timing can be used as an efficient and non-invasive preselection method for high developmental competent oocytes.

DOI： 10.1017/S0967199416000290

Web of Science

PubMed

Investigation of a Rotavirus Gastroenteritis Outbreak among Immunosuppressed Patients in a Hospital Setting.

Sugata K, Hull J, Wang H, Foytich K, Moon SS, Takahashi Y, Kojima S, Yoshikawa T, Jiang B

Journal of immunological techniques in infectious diseases 6 巻 ( 1 ) 2017年1月

Clinical utility of next-generation sequencing-based minimal residual disease in paediatric B-cell acute lymphoblastic leukaemia 査読有り国際誌 Open Access

Sekiya, Y; Xu, YY; Muramatsu, H; Okuno, Y; Narita, A; Suzuki, K; Wang, XN; Kawashima, N; Sakaguchi, H; Yoshida, N; Hama, A; Takahashi, Y; Kato, K; Kojima, S

BRITISH JOURNAL OF HAEMATOLOGY 176 巻 ( 2 ) 頁： 248 - 257 2017年1月

[Allogeneic hematopoietic stem cell transplantation using ATG: prophylaxis and treatment]. 査読有り

Nishio N, Takahashi Y, Kojima S

[Rinsho ketsueki] The Japanese journal of clinical hematology 58 巻 ( 10 ) 頁： 2104 - 2110 2017年

The Measurement of X-ray Fluoroscopy Input-output Characteristics in Angiography System. 査読有り

Hagihara Y, Umehara T, Matsumoto K, Fujita T, Ikeuchi Y, Fujikawa K, Takahashi Y, Kotoura N

Nihon Hoshasen Gijutsu Gakkai zasshi 73 巻 ( 2 ) 頁： 96 - 103 2017年

*Relapse of leukemia with loss of mismatched HLA due to uniparental disomy following haploidentical hematopoietic stem cell transplantation. 査読有り

Villalobos IB, Takahashi Y, Akatsuka Y, Muramatsu H, Nishio N, Hama A, Yagasaki H, Saji H, Kato M, Ogawa S, Kojima S.

Blood Epub ahead of print 巻頁： Epub ahead of print 2010年

*Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. 査読有り

Takahashi, Y., N. Harashima, S. Kajigaya, H. Yokoyama, E. Cherkasova, J.P. McCoy, K.I. Hanada, O. Mena, R. Kurlander, T. Abdul, R. Srinivasan, A. Lundqvist, E. Malinzak, N. Geller, M.I. Lerman, and R.W. Childs.

The Journal of Clinical Investigation 118 巻頁： 1099-1109. 2008年

*In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation. 査読有り

Takahashi Y, McCoy JP Jr, Carvallo C, Rivera C, Igarashi T, Srinivasan R, Young NS, and Childs RW

Blood 103 巻頁： 1383-1390 2004年

*An Allogeneic-Based Immunotherapy For Renal Cell Carcinoma. 招待有り査読有り

Takahashi Y, Childs, R

Clinical Cancer Research 10 巻 ( 18Pt2 ) 頁： 6353S-6359S 2004年

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