Updated on 2023/05/05

写真a

 
EBATA, Tomoki
 
Organization
Graduate School of Medicine Program in Integrated Medicine Musculoskeletal and Cutaneous Medicine Professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Professor
Contact information
メールアドレス

Degree 1

  1. 医学博士 ( 2002.9   名古屋大学 ) 

Research Interests 1

  1. hepatobiliary-pancreatic surgery

Research Areas 1

  1. Others / Others  / Digestive Organ Surgery

Research History 4

  1. 名古屋大学医学部附属病院消化器外科1 講師

    2009.1

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    Country:Japan

  2. 名古屋大学医学部付属病院消化器外科1 助教

    2007.4 - 2008.12

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    Country:Japan

  3. 名古屋大学医学部付属病院第一外科 助手

    2003.9 - 2007.3

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    Country:Japan

  4. 静岡県立静岡がんセンター肝胆膵外科 副医長

    2002.7 - 2003.8

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    Country:Japan

Education 2

  1. Nagoya University   Graduate School, Division of Medical Sciences

    1998.4 - 2002.9

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    Country: Japan

  2. Nagoya University   Faculty of Medicine

    1984.4 - 1990.3

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    Country: Japan

Professional Memberships 6

  1. 日本外科学会   理事

  2. 日本臨床外科学会   評議員

  3. 日本消化器病学会

  4. 日本胆道学会   評議員

  5. 日本肝胆膵外科学会   理事

  6. 日本消化器外科学会   評議員

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Papers 218

  1. Proposal to modify the International Union Against Cancer staging system for perihilar cholangiocarcinomas Reviewed

    T. Ebata, T. Kosuge, S. Hirano, M. Unno, M. Yamamoto, M. Miyazaki, N. Kokudo, T. Takada, M. Nagino

    British Journal of Surgery   Vol. 101   page: 79-88   2014.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  2. Hepatopancreatoduodenectomy for cholangiocarcinoma: a single-center review of 85 consecutive patients. Reviewed

    Ebata T, Yokoyama Y, Igami T, Sugawara G, Takahashi Y, Nimura Y, Nagino M.

    Ann Surg   Vol. 256 ( 2 ) page: 297-305   2012.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  3. Portal vein embolization before extended hepatectomy for biliary cancer: current technique and review of 494 consecutive embolizations. Reviewed

    Ebata T, Yokoyama Y, Igami T, Sugawara G, Takahashi Y, Nagino M

    Did Surg   Vol. 29 ( 1 ) page: 23-29   2012

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  4. Hilar cholangioplasty using omentum for ductal defect in biliobiliary fistula. Reviewed

    Ebata T, Takagi K, Nagino M.

    J Hepatobiliary Pancreat Sci   Vol. 18 ( 3 ) page: 458-462   2011.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  5. Impact of skeletal muscle mass on the prognosis of patients undergoing neoadjuvant chemotherapy for resectable or borderline resectable pancreatic cancer

    Nakajima Hiroki, Yamaguchi Junpei, Takami Hideki, Hayashi Masamichi, Kodera Yasuhiro, Nishida Yoshihiro, Watanabe Nobuyuki, Onoe Shunsuke, Mizuno Takashi, Yokoyama Yukihiro, Ebata Tomoki

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 28 ( 5 ) page: 688 - 697   2023.5

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  6. Two-step arterial reconstruction technique for en bloc resection of a large retroperitoneal liposarcoma involving the common iliac artery

    Sunagawa Masaki, Yokoyama Yukihiro, Banno Hiroshi, Sugimoto Masayuki, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Kawakatsu Shoji, Ebata Tomoki

    SURGERY TODAY     2023.4

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  7. The Goal of Intraoperative Blood Loss in Major Hepatobiliary Resection for Perihilar Cholangiocarcinoma: Saving Patients from a Heavy Complication Burden.

    Kawakatsu S, Mizuno T, Yamaguchi J, Watanabe N, Onoe S, Sunagawa M, Baba T, Igami T, Yokoyama Y, Imaizumi T, Ebata T

    Annals of surgery     2023.4

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    Language:English  

    DOI: 10.1097/SLA.0000000000005869

    PubMed

  8. Early Prediction of a Serious Postoperative Course in Perihilar Cholangiocarcinoma Trajectory Analysis of the Comprehensive Complication Index

    Kawakatsu Shoji, Yamaguchi Junpei, Mizuno Takashi, Watanabe Nobuyuki, Onoe Shunsuke, Igami Tsuyoshi, Yokoyama Yukihiro, Uehara Kay, Nagino Masato, Matsuo Keitaro, Ebata Tomoki

    ANNALS OF SURGERY   Vol. 277 ( 3 ) page: 475 - 483   2023.3

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  9. Efficacy of Extended Modification in Left Hemihepatectomy for Advanced Perihilar Cholangiocarcinoma Comparison Between H12345 ' 8 '-B-MHV and H1234-B

    Otsuka Shimpei, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Shimoyama Yoshie, Igami Tsuyoshi, Uehara Kay, Yokoyama Yukihiro, Nagino Masato, Ebata Tomoki

    ANNALS OF SURGERY   Vol. 277 ( 3 ) page: E585 - E591   2023.3

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  10. Cyclodextrin Conjugated alpha-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer

    Kano Mikiko takebayashi, Kokuryo Toshio, Baba Taisuke, Yamazaki Kimitoshi, Yamaguchi Junpei, Sunagawa Masaki, Ogura Atsushi, Watanabe Nobuyuki, Onoe Shunsuke, Miyata Kazushi, Mizuno Takashi, Uehara Kay, Igami Tsuyoshi, Yokoyama Yukihiro, Ebata Tomoki, Nagino Masato

    ANTICANCER RESEARCH   Vol. 43 ( 3 ) page: 1009 - 1016   2023.3

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  11. Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging

    Nakashima Yu, Yokoyama Yukihiro, Ogawa Hiroshi, Sakakibara Ayako, Sunagawa Masaki, Nishida Yoshihiro, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Kawakatsu Shoji, Igami Tsuyoshi, Ebata Tomoki

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 28 ( 3 ) page: 482 - 490   2023.3

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  12. Risk Factors for Muscle Loss During Neoadjuvant Therapy for Esophageal Cancer.

    Shimizu D, Miyata K, Fukaya M, Sugita S, Ebata T

    Anticancer research   Vol. 43 ( 3 ) page: 1309 - 1315   2023.3

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    Language:English  

    DOI: 10.21873/anticanres.16278

    PubMed

  13. Antitumor Effects of Deep Ultraviolet Irradiation for Pancreatic Cancer.

    Yamazaki K, Kokuryo T, Yamaguchi J, Sunagawa M, Ogura A, Watanabe N, Onoe S, Miyata K, Mizuno T, Uehara K, Igami T, Yokoyama Y, Ebata T, Nagino M

    Anticancer research   Vol. 43 ( 2 ) page: 621 - 630   2023.2

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    Language:English  

    DOI: 10.21873/anticanres.16198

    PubMed

  14. Impact of preoperative muscle mass and quality on surgical outcomes in patients undergoing major hepatectomy for perihilar cholangiocarcinoma

    Asai Yuichi, Yamaguchi Junpei, Mizuno Takashi, Onoe Shunsuke, Watanabe Nobuyuki, Igami Tsuyoshi, Uehara Kay, Yokoyama Yukihiro, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 30 ( 2 ) page: 202 - 211   2023.2

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  15. Tranexamic acid and blood loss in pancreaticoduodenectomy: TAC-PD randomized clinical trial

    Ishii Kenta, Yokoyama Yukihiro, Yonekawa Yoshihiko, Hayashi Daisuke, Kinoshita Fumie, Kuwatsuka Yachiyo, Okuno Masataka, Natsume Seiji, Minami Takayuki, Sugawara Gen, Seita Kazuaki, Sato Fumiya, Aoba Taro, Shimizu Yasuhiro, Kurumiya Yasuhiro, Maeda Atsuyuki, Yamaguchi Ryuzo, Hiramatsu Kazuhiro, Ebata Tomoki

    BRITISH JOURNAL OF SURGERY   Vol. 110 ( 2 ) page: 159 - 165   2023.1

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  16. [Up-to-date surgical treatment for biliary tract cancer].

    Ebata T, Mizuno T, Yokoyama Y

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   Vol. 120 ( 4 ) page: 309 - 318   2023

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    Language:Japanese  

    DOI: 10.11405/nisshoshi.120.309

    PubMed

  17. Impact of combined resection of the internal iliac artery on loss of volume of the gluteus muscles after pelvic exenteration

    Murata Yuki, Uehara Kay, Ogura Atsushi, Ishigaki Satoko, Aiba Toshisada, Mizuno Takashi, Kokuryo Toshio, Yokoyama Yukihiro, Yatsuya Hiroshi, Ebata Tomoki

    SURGERY TODAY     2022.12

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  18. Minimum radial margin in pelvic exenteration for locally advanced or recurrent rectal cancer

    Aiba Toshisada, Uehara Kay, Tsuyuki Yuta, Ogura Atsushi, Murata Yuki, Mizuno Takashi, Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Ebata Tomoki

    EJSO   Vol. 48 ( 12 ) page: 2502 - 2508   2022.12

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  19. Is a specific T classification needed for extrahepatic intraductal papillary neoplasm of the bile duct (IPNB) type 2 associated with invasive carcinoma?

    Mitake Yasuhiro, Onoe Shunsuke, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Sunagawa Masaki, Watanabe Nobuyuki, Kawakatsu Shoji, Shimoyama Yoshie, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES     2022.11

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  20. Early volume loss of skeletal muscle after esophagectomy: a risk for late-onset postoperative pneumonia

    Nishimura Koudai, Miyata Kazushi, Fukaya Masahide, Yokoyama Yukihiro, Uehara Kay, Yamaguchi Junpei, Mizuno Takashi, Onoe Shunsuke, Ogura Atsushi, Ebata Tomoki

    DISEASES OF THE ESOPHAGUS   Vol. 35 ( 11 )   2022.11

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  21. A proposal of drain removal criteria in hepatobiliary resection

    Watanabe Nobuyuki, Mizuno Takashi, Yamaguchi Junpei, Yokoyama Yukihiro, Igami Tsuyoshi, Onoe Shunsuke, Uehara Kay, Sunagawa Masaki, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 29 ( 9 ) page: 974 - 982   2022.9

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  22. Trefoil factor 1 inhibits the development of esophageal adenocarcinoma from Barrett's epithelium

    Hasebe Keiji, Yamazaki Kimitoshi, Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Miyata Kazushi, Fukaya Masahide, Nagino Masato, Ebata Tomoki

    LABORATORY INVESTIGATION   Vol. 102 ( 8 ) page: 885 - 895   2022.8

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  23. Comparison of an Inside Stent and a Fully Covered Self-Expandable Metallic Stent as Preoperative Biliary Drainage for Patients with Resectable Perihilar Cholangiocarcinoma

    Mori Hiroshi, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Yamao Kentaro, Mizutani Yasuyuki, Iida Tadashi, Nakamura Masanao, Ishigami Masatoshi, Onoe Shunsuke, Mizuno Takashi, Ebata Tomoki, Fujishiro Mitsuhiro

    CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 2022   page: 3005210   2022.7

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  24. Mild Prognostic Impact of Postoperative Complications on Long-term Survival of Perihilar Cholangiocarcinoma

    Kawakatsu Shoji, Ebata Tomoki, Watanabe Nobuyuki, Onoe Shunsuke, Yamaguchi Junpei, Mizuno Takashi, Igami Tsuyoshi, Yokoyama Yukihiro, Matsuo Keitaro, Nagino Masato

    ANNALS OF SURGERY   Vol. 276 ( 1 ) page: 146 - 152   2022.7

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  25. Superiority of clinical American Joint Committee on Cancer T classification for perihilar cholangiocarcinoma

    Yamada Mihoko, Mizuno Takashi, Yamaguchi Junpei, Yokoyama Yukihiro, Igami Tsuyoshi, Onoe Shunsuke, Watanabe Nobuyuki, Uehara Kay, Matsuo Keitaro, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 29 ( 7 ) page: 768 - 777   2022.7

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  26. Multidisciplinary surgical approach for renal cell carcinoma with inferior vena cava tumor thrombus

    Yano Daisuke, Yokoyama Yukihiro, Tokuda Yoshiyuki, Kato Masashi, Mashiko Yuji, Kuwabara Fumiaki, Ebata Tomoki, Usui Akihiko

    SURGERY TODAY   Vol. 52 ( 7 ) page: 1016 - 1022   2022.7

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  27. The ELEANOR noncoding RNA expression contributes to cancer dormancy and predicts late recurrence of estrogen receptor-positive breast cancer

    Fukuoka Megumi, Ichikawa Yuichi, Osako Tomo, Fujita Tomoko, Baba Satoko, Takeuchi Kengo, Tsunoda Nobuyuki, Ebata Tomoki, Ueno Takayuki, Ohno Shinji, Saitoh Noriko

    CANCER SCIENCE   Vol. 113 ( 7 ) page: 2336 - 2351   2022.7

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  28. Stoma creation is associated with a low incidence of midline incisional hernia after colorectal surgery: the "fighting over the fascia" theory concerning the incision and stoma hole

    Ohara Noriaki, Uehara Kay, Ogura Atsushi, Sando Masanori, Aiba Toshisada, Murata Yuki, Mizuno Takashi, Toshio Kokuryo, Yokoyama Yukihiro, Ishigaki Satoko, Li Yuanying, Yatsuya Hiroshi, Ebata Tomoki

    SURGERY TODAY   Vol. 52 ( 6 ) page: 953 - 963   2022.6

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  29. Results of a Phase II Study on the Use of Neoadjuvant Chemotherapy (FOLFIRINOX or GEM/nab-PTX) for Borderline-resectable Pancreatic Cancer (NUPAT-01)

    Yamaguchi Junpei, Yokoyama Yukihiro, Fujii Tsutomu, Yamada Suguru, Takami Hideki, Kawashima Hiroki, Ohno Eizaburo, Ishikawa Takuya, Maeda Osamu, Ogawa Hiroshi, Kodera Yasuhiro, Nagino Masato, Ebata Tomoki

    ANNALS OF SURGERY   Vol. 275 ( 6 ) page: 1043 - 1049   2022.6

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  30. Clinical guidelines for primary sclerosing cholangitis 2017 (vol 53, pg 1006, 2018)

    Isayama Hiroyuki, Tazuma Susumu, Kokudo Norihiro, Tanaka Atsushi, Tsuyuguchi Toshio, Nakazawa Takahiro, Notohara Kenji, Mizuno Suguru, Akamatsu Nobuhisa, Serikawa Masahiro, Naitoh Itaru, Hirooka Yoshiki, Wakai Toshifumi, Itoi Takao, Ebata Tomoki, Okaniwa Shinji, Kamisawa Terumi, Kawashima Hiroki, Kanno Atsushi, Kubota Keiichi, Tabata Masami, Unno Michiaki, Takikawa Hajime

    JOURNAL OF GASTROENTEROLOGY   Vol. 57 ( 6 ) page: 453 - 454   2022.6

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  31. Role of resection for extrahepatopulmonary metastases of colon cancer.

    Mishina T, Uehara K, Ogura A, Murata Y, Aiba T, Mizuno T, Yokoyama Y, Ebata T

    Japanese journal of clinical oncology     2022.4

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    Language:English  

    DOI: 10.1093/jjco/hyac045

    PubMed

  32. Transplantation of human iPSC-derived muscle stem cells in the diaphragm of Duchenne muscular dystrophy model mice

    Miura Yasutomo, Sato Mase, Kuwahara Toshie, Ebata Tomoki, Tabata Yasuhiko, Sakurai Hidetoshi

    PLOS ONE   Vol. 17 ( 4 ) page: e0266391   2022.4

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  33. Reply to comment on "Adjuvant S-1 vs gemcitabine for node-positive perihilar cholangiocarcinoma"

    Takahashi Daigoro, Mizuno Takashi, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 29 ( 4 ) page: E29 - E29   2022.4

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  34. Original Research Individual patient data meta-analysis of adjuvant gemcitabine-based chemotherapy for biliary tract cancer: combined analysis of the BCAT and PRODIGE-12 studies

    Edeline Julien, Hirano Satoshi, Bertaut Aurelie, Konishi Masaru, Benabdelghani Meher, Uesaka Katsuhiko, Watelet Jerome, Ohtsuka Masayuki, Hammel Pascal, Kaneoka Yuji, Joly Jean-Paul, Yamamoto Masakazu, Monard Laure, Ambo Yoshiyasu, Louvet Christophe, Ando Masahiko, Malka David, Nagino Masato, Phelip Jean-Marc, Ebata Tomoki

    EUROPEAN JOURNAL OF CANCER   Vol. 164   page: 80 - 87   2022.3

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  35. [A Greater Than Four-Year Survival of a Patient with Inoperable Hilar Cholangiocarcinoma following Portal Vein Embolization and Administration of S-1].

    Hasuike Y, Higuchi I, Ishikawa A, Mori Y, Urano N, Kominami H, Sugiyama T, Ebata T

    Gan to kagaku ryoho. Cancer & chemotherapy   Vol. 49 ( 3 ) page: 345 - 347   2022.3

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    Language:Japanese  

    PubMed

  36. Combined Vascular Resection for Locally Advanced Perihilar Cholangiocarcinoma

    Mizuno Takashi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Kamei Yuzuru, Nagino Masato

    ANNALS OF SURGERY   Vol. 275 ( 2 ) page: 382 - 390   2022.2

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  37. A long-term survivor of advanced retroperitoneal dedifferentiated liposarcoma: a successful multimodal approach with extended resection and chemotherapy

    Nakahashi Koichi, Yokoyama Yukihiro, Fukaya Masahide, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Ebata Tomoki

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 1 ) page: 200 - 207   2022.2

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  38. Predicting Inchinkoto efficacy, in patients with obstructive jaundice associated with malignant tumors, through pharmacomicrobiomics

    Yamashita Hiromasa, Nishiyama Mitsue, Ohbuchi Katsuya, Kanno Hitomi, Tsuchiya Kazuaki, Yamaguchi Junpei, Mizuno Takashi, Ebata Tomoki, Nagino Masato, Yokoyama Yukihiro

    PHARMACOLOGICAL RESEARCH   Vol. 175   page: 105981   2022.1

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  39. The significance of the time to arterial perfusion in intraoperative ICG angiography during colorectal surgery

    Aiba Toshisada, Uehara Kay, Ogura Atsushi, Tanaka Aya, Yonekawa Yoshihiko, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki, Nagino Masato

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 35 ( 12 ) page: 7227 - 7235   2021.12

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  40. Trefoil factor family 2 inhibits cholangiocarcinogenesis by regulating the PTEN pathway in mice

    Hasebe Keiji, Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Ochiai Yosuke, Nagino Masato, Ebata Tomoki

    CARCINOGENESIS   Vol. 42 ( 12 ) page: 1496 - 1505   2021.12

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  41. Comprehensive metabolome analysis for the pharmacological action of inchinkoto, a hepatoprotective herbal medicine

    Yamashita Hiromasa, Ohbuchi Katsuya, Nagino Masato, Ebata Tomoki, Tsuchiya Kazuaki, Kushida Hirotaka, Yokoyama Yukihiro

    METABOLOMICS   Vol. 17 ( 12 ) page: 106   2021.12

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  42. Neoadjuvant docetaxel, oxaliplatin plus S-1 for treating clinical stage III squamous cell carcinoma of the esophagus: Study protocol of an open-label phase II trial

    Kanda Mitsuro, Shimizu Dai, Miyata Kazushi, Maeda Osamu, Tanaka Chie, Inokawa Yoshikuni, Hattori Norofumi, Hayashi Masamichi, Ando Masahiko, Kuwatsuka Yachiyo, Murotani Kenta, Nakayama Goro, Koike Masahiko, Ando Yuichi, Ebata Tomoki, Kodera Yasuhiro

    CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS   Vol. 24   page: 100853   2021.12

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  43. Impact of synbiotics treatment on bacteremia induced during neoadjuvant chemotherapy for esophageal cancer: A randomised controlled trial

    Fukaya Masahide, Yokoyama Yukihiro, Usui Hiroaki, Fujieda Hironori, Sakatoku Yayoi, Takahashi Takamasa, Miyata Kazushi, Niikura Mai, Sugimoto Takuya, Asahara Takashi, Nagino Masato, Ebata Tomoki

    CLINICAL NUTRITION   Vol. 40 ( 12 ) page: 5781 - 5791   2021.12

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  44. A clinicopathological reappraisal of intraductal papillary neoplasm of the bile duct (IPNB): a continuous spectrum with papillary cholangiocarcinoma in 181 curatively resected cases

    Onoe Shunsuke, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Watanabe Nobuyuki, Otsuka Shinpei, Nakamura Shigeo, Shimoyama Yoshie, Nagino Masato

    HPB   Vol. 23 ( 10 ) page: 1525 - 1532   2021.10

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  45. [Ⅱ.Treatment for Recurrent Cholangiocarcinoma].

    Watanabe N, Yokoyama Y, Igami T, Uehara K, Mizuno T, Yamaguchi J, Miyata K, Onoe S, Ogura A, Ebata T

    Gan to kagaku ryoho. Cancer & chemotherapy   Vol. 48 ( 10 ) page: 1223 - 1226   2021.10

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    Language:Japanese  

    PubMed

  46. Adjuvant S-1 vs gemcitabine for node-positive perihilar cholangiocarcinoma: A propensity score-adjusted analysis

    Takahashi Daigoro, Mizuno Takashi, Yokoyama Yukihiro, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Maeda Osamu, Ando Masahiko, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 9 ) page: 716 - 726   2021.9

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  47. The carcinoembryonic antigen ratio is a potential predictor of survival in recurrent colorectal cancer

    Suzuki Yumi, Ogura Atsushi, Uehara Kay, Aiba Toshisada, Ohara Noriaki, Murata Yuki, Jinno Takanori, Mishina Takuya, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 26 ( 7 ) page: 1264 - 1271   2021.7

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  48. Importance of "muscle" and "intestine" training before major HPB surgery: A review

    Yokoyama Yukihiro, Nagino Masato, Ebata Tomoki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 7 ) page: 545 - 555   2021.7

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    Language:Japanese  

    DOI: 10.1002/jhbp.835

    Web of Science

    PubMed

  49. Oncological Superiority of Right-sided Hepatectomy Over Left-sided Hepatectomy as Surgery for Perihilar Cholangiocarcinoma Truth or Biased View?

    Nagino Masato, Ebata Tomoki, Mizuno Takashi

    ANNALS OF SURGERY   Vol. 274 ( 1 ) page: 31 - 32   2021.7

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  50. Proposal of a New Comprehensive Notation for Hepatectomy The "New World'' Terminology

    Nagino Masato, DeMatteo Ronald, Lang Hauke, Cherqui Daniel, Malago Massimo, Kawakatsu Shoji, DeOliveira Michelle L., Adam Rene, Aldrighetti Luca, Boudjema Karim, Chapman William, Clary Bryan, de Santibanes Eduardo, Dong Jiahong, Ebata Tomoki, Endo Itaru, Geller David, Guglielmi Alfredo, Kato Tomoaki, Lee Sung-Gyu, Lodge Peter, Nadalin Silvio, Pinna Antonio, Polak Wojciech, Soubrane Olivier, Clavien Pierre-Alain

    ANNALS OF SURGERY   Vol. 274 ( 1 ) page: 1 - 3   2021.7

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  51. A presurgical prognostic stratification based on nutritional assessment and carbohydrate antigen 19-9 in pancreatic carcinoma: An approach with nonanatomic biomarkers

    Onoe Shunsuke, Yokoyama Yukihiro, Kokuryo Toshio, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Watanabe Nobuyuki, Kawakatsu Shoji, Ebata Tomoki

    SURGERY   Vol. 169 ( 6 ) page: 1463 - 1470   2021.6

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  52. Indications for neoadjuvant treatment based on risk factors for poor prognosis before and after neoadjuvant chemotherapy alone in patients with locally advanced rectal cancer

    Ogura Atsushi, Uehara Kay, Aiba Toshisada, Sando Masanori, Tanaka Aya, Ohara Noriaki, Murata Yuki, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Ebata Tomoki, Kodera Yasuhiro, Nagino Masato

    EJSO   Vol. 47 ( 5 ) page: 1005 - 1011   2021.5

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  53. Oncologic Reappraisal of Bile Duct Resection for Middle-Third Cholangiocarcinoma

    Jikei Kosuke, Ebata Tomoki, Mizuno Takashi, Kyokane Takanori, Matsubara Hideo, Yokoyama Shinya, Kato Kenji, Suzumura Kiyoshi, Hashimoto Mizuo, Kawai Satoru, Nagino Masato

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 4 ) page: 1990 - 1999   2021.4

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  54. ASO Author Reflections: Bile Duct Resection-Is It Beneficial for Distal Cholangiocarcinoma?

    Ebata Tomoki, Jikei Kosuke, Mizuno Takashi

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 4 ) page: 2000 - 2000   2021.4

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  55. Clinical importance of "occult-bacterial translocation" in patients undergoing highly invasive gastrointestinal surgery: A review

    Yokoyama Yukihiro, Fukaya Masahide, Mizuno Takashi, Ebata Tomoki, Asahara Takashi, Nagino Masato

    SURGERY TODAY   Vol. 51 ( 4 ) page: 485 - 492   2021.4

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  56. Hepatopancreatoduodenectomy with simultaneous resection of the portal vein and hepatic artery for locally advanced cholangiocarcinoma: Short- and long-term outcomes of superextended surgery

    Nagino Masato, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 4 ) page: 376 - 386   2021.4

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    Language:Japanese  

    DOI: 10.1002/jhbp.914

    Web of Science

    PubMed

  57. Premalignant pancreatic cells seed stealth metastasis in distant organs in mice

    Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Ebata Tomoki, Ochiai Yosuke, Nagino Masato

    ONCOGENE   Vol. 40 ( 12 ) page: 2273 - 2284   2021.3

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  58. Application of fluorescent cholangiography during single-incision laparoscopic cholecystectomy in the cystohepatic duct without preoperative diagnosis

    Asai Yuichi, Igami Tsuyoshi, Ebata Tomoki, Yokoyama Yukihiro, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    ANZ JOURNAL OF SURGERY   Vol. 91 ( 3 ) page: 470 - 472   2021.3

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  59. A Study on Radial Margin Status in Resected Perihilar Cholangiocarcinoma

    Shinohara Kentaro, Ebata Tomoki, Shimoyama Yoshie, Mizuno Takashi, Yokoyama Yukihiro, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    ANNALS OF SURGERY   Vol. 273 ( 3 ) page: 572 - 578   2021.3

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  60. The survival benefit of neoadjuvant chemotherapy for resectable colorectal liver metastases with high tumor burden score

    Yonekawa Yoshihiko, Uehara Kay, Mizuno Takashi, Aiba Toshisada, Ogura Atsushi, Mukai Toshiki, Yokoyama Yukihiro, Ebata Tomoki, Kodera Yasuhiro, Nagino Masato

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 26 ( 1 ) page: 126 - 134   2021.1

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  61. Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English edition

    Nagino Masato, Hirano Satoshi, Yoshitomi Hideyuki, Aoki Taku, Uesaka Katsuhiko, Unno Michiaki, Ebata Tomoki, Konishi Masaru, Sano Keiji, Shimada Kazuaki, Shimizu Hiroaki, Higuchi Ryota, Wakai Toshifumi, Isayama Hiroyuki, Okusaka Takuji, Tsuyuguchi Toshio, Hirooka Yoshiki, Furuse Junji, Maguchi Hiroyuki, Suzuki Kojiro, Yamazaki Hideya, Kijima Hiroshi, Yanagisawa Akio, Yoshida Masahiro, Yokoyama Yukihiro, Mizuno Takashi, Endo Itaru

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 1 ) page: 26 - 54   2021.1

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    DOI: 10.1002/jhbp.870

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  62. Impact of Perioperative Steroid Administration in Patients Undergoing Major Hepatectomy with Extrahepatic Bile Duct Resection: A Randomized Controlled Trial

    Onoe Shunsuke, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Watanabe Nobuyuki, Suzuki Shogo, Nishiwaki Kimitoshi, Ando Masahiko, Nagino Masato

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 1 ) page: 121 - 130   2021.1

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  63. Impact of the preoperative body composition indexes on intraoperative blood loss in patients undergoing pancreatoduodenectomy

    Ishii Kenta, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGERY TODAY   Vol. 51 ( 1 ) page: 52 - 60   2021.1

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  64. New method for the assessment of perineural invasion from perihilar cholangiocarcinoma

    Tanaka Hiroshi, Igami Tsuyoshi, Shimoyama Yoshie, Ebata Tomoki, Yokoyama Yukihiro, Mori Kensaku, Nagino Masato

    SURGERY TODAY   Vol. 51 ( 1 ) page: 136 - 143   2021.1

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  65. The role of surgery for locally recurrent and second recurrent rectal cancer with metastatic disease

    Tanaka Aya, Uehara Kay, Aiba Toshisada, Ogura Atsushi, Mukai Toshiki, Yokoyama Yukihiro, Ebata Tomoki, Kodera Yasuhiro, Nagino Masato

    SURGICAL ONCOLOGY-OXFORD   Vol. 35   page: 328 - 335   2020.12

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  66. ASO Author Reflections: Is Perioperative Steroids Administration Beneficial for Patients Undergoing Major Hepatectomy with Extrahepatic Bile Duct Resection?

    Onoe Shunsuke, Yokoyama Yukihiro, Ebata Tomoki, Nagino Masato

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( Suppl 3 ) page: 808 - 809   2020.12

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  67. Pelvic exenteration associated with future renal dysfunction

    Sando Masanori, Uehara Kay, Li Yuanying, Alba Toshisada, Ogura Atsushi, Ebata Tomoki, Kodera Yasuhiro, Yatsuya Hiroshi, Nagino Masato

    SURGERY TODAY   Vol. 50 ( 12 ) page: 1601 - 1609   2020.12

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  68. Study of the Portal Branches Arising from the Cranial Part of the Umbilical Portion of the Left Portal Vein: Implications for Anatomic Right Hepatic Trisectionectomy

    Minami Takayuki, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 44 ( 12 ) page: 4231 - 4235   2020.12

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  69. The influence of the preoperative thickness of the abdominal cavity on the gastrojejunal anatomic position and delayed gastric emptying after pancreatoduodenectomy

    Watanabe Nobuyuki, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Nagino Masato

    HPB   Vol. 22 ( 12 ) page: 1695 - 1702   2020.12

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  70. What is the impact of systemic chemotherapy for lateral lymph nodes in patients with locally advanced low rectal cancer?

    Ogura Atsushi, Uehara Kay, Aiba Toshisada, Hattori Norifumi, Nakayama Goro, Maeda Osamu, Ando Yuichi, Kodera Yasuhiro, Ebata Tomoki, Nagino Masato

    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE   Vol. 35 ( 11 ) page: 2073 - 2080   2020.11

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  71. Chemotherapy for biliary tract cancer: real-world experience in a single institute

    Maeda Osamu, Ebata Tomoki, Shimokata Tomoya, Matsuoka Ayumu, Inada-Inoue Megumi, Morita Sachi, Takano Yuko, Urakawa Hiroshi, Miyai Yuki, Sugishita Mihoko, Mitsuma Ayako, Ando Masahiko, Mizuno Takashi, Nagino Masato, Ando Yuichi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 4 ) page: 725 - 733   2020.11

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  72. How long should follow-up be continued after R0 resection of perihilar cholangiocarcinoma?

    Nakahashi Koichi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGERY   Vol. 168 ( 4 ) page: 617 - 624   2020.10

  73. Adjuvant gemcitabine-based chemotherapy for biliary tract cancer: Pooled analysis of the BCAT and PRODIGE-12 studies

    Edeline J., Hirano S., Bertaut A., Konishi M., Benabdelghani M., Uesaka K., Watelet J., Ohtsuka M., Hammel P., Kaneoka Y., Joly J-P., Yamamoto M., Jouffroy C., Ambo Y., Louvet C., Ando M., Malka D., Nagino M., Phelip J. M., Ebata T.

    ANNALS OF ONCOLOGY   Vol. 31   page: S262 - S262   2020.9

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  74. Trefoil Factor Family 1 Inhibits the Development of Hepatocellular Carcinoma by Regulating beta-Catenin Activation

    Ochiai Yosuke, Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Ebata Tomoki, Nagino Masato

    HEPATOLOGY   Vol. 72 ( 2 ) page: 503 - 517   2020.8

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  75. Phase 2 Trial of Adjuvant Chemotherapy With S-1 for Node-Positive Biliary Tract Cancer (N-SOG 09)

    Seita Kazuaki, Ebata Tomoki, Mizuno Takashi, Maeda Atsuyuki, Yamaguchi Ryuzo, Kurumiya Yasuhiro, Sakamoto Eiji, Hiramatsu Kazuhiro, Ando Masahiko, Nagino Masato

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 7 ) page: 2348 - 2356   2020.7

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  76. ASO Author Reflections: Phase II Trial of Adjuvant Chemotherapy with S-1 for Node-Positive Biliary Tract Cancer (N-SOG 09).

    Ebata T, Mizuno T

    Annals of surgical oncology   Vol. 27 ( 7 ) page: 2357 - 2358   2020.7

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    DOI: 10.1245/s10434-020-08364-2

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  77. Postoperative infectious complications caused by multidrug-resistant pathogens in patients undergoing major hepatectomy with extrahepatic bile duct resection

    Sugawara Gen, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Yamaguchi Junpei, Mizuno Takashi, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGERY   Vol. 167 ( 6 ) page: 950 - 956   2020.6

  78. Advanced hilar cholangiocarcinoma: An aggressive surgical approach for the treatment of advanced hilar cholangiocarcinoma: Perioperative management, extended procedures, and multidisciplinary approaches

    Mizuno Takashi, Ebata Tomoki, Nagino Masato

    SURGICAL ONCOLOGY-OXFORD   Vol. 33   page: 201 - 206   2020.6

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  79. Evaluation of segment 4 portal vein embolization added to right portal vein for right hepatic trisectionectomy: A retrospective propensity score-matched study

    Ito Jun, Komada Tomohiro, Suzuki Kojiro, Matsushima Masaya, Nakatochi Masahiro, Kobayashi Yumiko, Ebata Tomoki, Naganawa Shinji, Nagino Masato

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 27 ( 6 ) page: 299 - 306   2020.6

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    DOI: 10.1002/jhbp.723

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  80. Study on the Segmentation of the Right Posterior Sector of the Liver

    Minami Takayuki, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 44 ( 3 ) page: 896 - 901   2020.3

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  81. Predictive performance of Blumgart T staging for perihilar cholangiocarcinoma in a Japanese center

    Ebata Tomoki, Mizuno Takashi, Yokoyama Yukihiro, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 27 ( 3 ) page: 132 - 140   2020.3

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    DOI: 10.1002/jhbp.694

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  82. Tranexamic ACid during PancereaticoDuodenectomy (TAC-PD): study protocol for a multicentre randomised, blind, placebo-controlled trial

    Ishii Kenta, Yokoyama Yukihiro, Yonekawa Yoshihiko, Ebata Tomoki

    BMJ OPEN   Vol. 10 ( 11 ) page: e040914   2020

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  83. [Benign hilar bile duct stricture resected as perihilar cholangiocarcinoma].

    Nagino M, Ebata T, Otsuka S

    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology   Vol. 117 ( 8 ) page: 679 - 688   2020

  84. The impact of cervical lymph node dissection on acid and duodenogastroesophageal reflux after intrathoracic esophagogastrostomy following transthoracic esophagectomy

    Asai Soichiro, Fukaya Masahide, Miyata Kazushi, Itatsu Keita, Miyahara Ryoji, Furukawa Kazuhiro, Ebata Tomoki, Nagino Masato

    SURGERY TODAY   Vol. 49 ( 12 ) page: 1029 - 1034   2019.12

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  85. A case of small in situ perihilar cholangiocarcinoma incidentally accompanied by benign bile duct stricture after open cholecystectomy

    Maeda Takashi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGICAL CASE REPORTS   Vol. 5 ( 1 ) page: 177   2019.12

  86. Postoperative Pancreatic Fistula in Surgery for Perihilar Cholangiocarcinoma

    Watanabe Nobuyuki, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 43 ( 12 ) page: 3094 - 3100   2019.12

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  87. TREFOIL FACTOR FAMILY 1 INHIBITS THE DEVELOPMENT OF HEPATOCELLULAR CARCINOMA BY REGULATING B-CATENIN ACTIVATION

    Ochiai Yosuke, Yamaguchi Junpei, Kokuryo Toshio, Yokoyama Yukihiro, Ebata Tomoki, Nagino Masato

    HEPATOLOGY   Vol. 70   page: 1196A - 1196A   2019.10

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  88. Discrepancy between volume and functional recovery in early phase liver regeneration following extended hepatectomy with extrahepatic bile duct resection

    Maeda Takashi, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Ando Masahiko, Nagino Masato

    HEPATOLOGY RESEARCH   Vol. 49 ( 10 ) page: 1227 - 1235   2019.10

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  89. Benign hilar bile duct strictures resected as perihilar cholangiocarcinoma

    Otsuka S., Ebata T., Yokoyama Y., Igami T., Mizuno T., Yamaguchi J., Onoe S., Watanabe N., Shimoyama Y., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 106 ( 11 ) page: 1504 - 1510   2019.10

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  90. DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death

    Itoh Katsuhiko, Ebata Takahiro, Hirata Hiroaki, Torii Takeru, Sugimoto Wataru, Onodera Keigo, Nakajima Wataru, Uehara Ikuno, Okuzaki Daisuke, Yamauchi Shota, Budirahardja Yemima, Nishikata Takahito, Tanaka Nobuyuki, Kawauchi Keiko

    MOLECULES   Vol. 24 ( 17 )   2019.9

  91. Occult synchronous liver metastasis from perihilar cholangiocarcinoma

    Ohiwa Takashi, Ebata Tomoki, Mizuno Takashi, Yokoyama Yukihiro, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGERY   Vol. 166 ( 3 ) page: 290 - 296   2019.9

  92. Cholangiographic Tumor Classification for Simple Patient Selection Prior to Hepatopancreatoduodenectomy for Cholangiocarcinoma

    Toyoda Yoshitaka, Ebata Tomoki, Mizuno Takashi, Yokoyama Yukihiro, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26 ( 9 ) page: 2971 - 2979   2019.9

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  93. Preoperative course of patients undergoing endoscopic nasobiliary drainage during the management of resectable perihilar cholangiocarcinoma

    Maeda Takashi, Ebata Tomoki, Yokoyama Yukihiro, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Kawashima Hiroki, Nagino Masato

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 26 ( 8 ) page: 341 - 347   2019.8

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    DOI: 10.1002/jhbp.640

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  94. Author response to comment on: Major hepatectomy with or without pancreatoduodenectomy for advanced gallbladder cancer

    Mizuno T., Ebata T., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 106 ( 8 ) page: 1101 - +   2019.7

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  95. Left trisectionectomy combined with resection of the right hepatic vein and inferior vena cava after right hepatic vein embolization for advanced intrahepatic cholangiocarcinoma

    Suzuki Toshihiro, Ebata Tomoki, Yokoyama Yukihiro, Mizuno Takashi, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Nagino Masato

    SURGICAL CASE REPORTS   Vol. 5 ( 1 ) page: 98   2019.6

  96. Is constant negative pressure for external drainage of the main pancreatic duct useful in preventing pancreatic fistula following pancreatoduodenectomy?

    Sunagawa Masaki, Yokoyama Yukihiro, Yamaguchi Junpei, Ebata Tomoki, Sugawara Gen, Igami Tsuyoshi, Mizuno Takashi, Nagino Masato

    PANCREATOLOGY   Vol. 19 ( 4 ) page: 602 - 607   2019.6

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  97. NEK2 Is an Effective Target for Cancer Therapy With Potential to Induce Regression of Multiple Human Malignancies

    Kokuryo Toshio, Yokoyama Yukihiro, Yamaguchi Junpei, Tsunoda Nobuyuki, Ebata Tomoki, Nagino Masato

    ANTICANCER RESEARCH   Vol. 39 ( 5 ) page: 2251 - 2258   2019.5

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  98. Clinical value of additional resection of a margin-positive distal bile duct in perihilar cholangiocarcinoma

    Otsuka S., Ebata T., Yokoyama Y., Mizuno T., Tsukahara T., Shimoyama Y., Ando M., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 106 ( 6 ) page: 774 - 782   2019.5

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  99. Pleural dissemination of cholangiocarcinoma caused by percutaneous transhepatic biliary drainage during the management of resectable cholangiocarcinoma

    Yamashita Hiromasa, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Onoe Shunsuke, Watanabe Nobuyuki, Ando Masahiko, Nagino Masato

    SURGERY   Vol. 165 ( 5 ) page: 912 - 917   2019.5

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  100. Major hepatectomy with or without pancreatoduodenectomy for advanced gallbladder cancer

    Mizuno T., Ebata T., Yokoyama Y., Igami T., Yamaguchi J., Onoe S., Watanabe N., Ando M., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 106 ( 5 ) page: 626 - 635   2019.4

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  101. Proposal for a new classification for perihilar cholangiocarcinoma based on tumour depth

    Shinohara K., Ebata T., Shimoyama Y., Nakaguro M., Mizuno T., Matsuo K., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 106 ( 4 ) page: 427 - 435   2019.3

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  102. Trefoil Factor Family 1 (TFF1) Inhibits Epithelial-mesenchymal Transition and Enhances the Chemosensitivity of Pancreatic Ductal Adenocarcinoma (PDAC)

    Yamaguchi J., Kokuryo T., Yokoyama Y., Ebata T., Nagino M.

    PANCREAS   Vol. 48 ( 10 ) page: 1551 - 1552   2019

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  103. Comparison between autologous and homologous blood transfusions in liver resection for biliary tract cancer: a propensity score matching analysis

    Onoe Shunsuke, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Watanabe Nobuyuki, Nagino Masato

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 25 ( 12 ) page: 550 - 559   2018.12

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    DOI: 10.1002/jhbp.592

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  104. Loss of trefoil factor 1 inhibits biliary regeneration but accelerates the hepatic differentiation of progenitor cells in mice

    Hayashi Yuki, Yamaguchi Junpei, Kokuryo Toshio, Ebata Tomoki, Yokoyama Yukihiro, Nagino Masato

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   Vol. 506 ( 1 ) page: 12 - 19   2018.11

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  105. Surgery for perihilar cholangiocarcinoma from a viewpoint of age: Is it beneficial to octogenarians in an aging society?

    Akashi Kumiko, Ebata Tomoki, Mizuno Takashi, Yokoyama Yukihiro, Igami Tsuyoshi, Yamaguchi Junpei, Onoe Shunsuke, Nagino Masato

    SURGERY   Vol. 164 ( 5 ) page: 1023 - 1029   2018.11

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  106. Application of three-dimensional print in minor hepatectomy following liver partition between anterior and posterior sectors

    Igami Tsuyoshi, Nakamura Yoshihiko, Oda Masahiro, Tanaka Hiroshi, Nojiri Motoi, Ebata Tomoki, Yokoyama Yukihiro, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Mori Kensaku, Nagino Masato

    ANZ JOURNAL OF SURGERY   Vol. 88 ( 9 ) page: 882 - 885   2018.9

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  107. Clinical guidelines for primary sclerosing cholangitis 2017

    Isayama Hiroyuki, Tazuma Susumu, Kokudo Norihiro, Tanaka Atsushi, Tsuyuguchi Toshio, Nakazawa Takahiro, Notohara Kenji, Mizuno Suguru, Akamatsu Nobuhisa, Serikawa Masahiro, Naitoh Itaru, Hirooka Yoshiki, Wakai Toshifumi, Itoi Takao, Ebata Tomoki, Okaniwa Shinji, Kamisawa Terumi, Kawashima Hiroki, Kanno Atsushi, Kubota Keiichi, Tabata Masami, Unno Michiaki, Takikawa Hajime

    JOURNAL OF GASTROENTEROLOGY   Vol. 53 ( 9 ) page: 1006 - 1034   2018.9

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  108. Trefoil factor 1 inhibits epithelial-mesenchymal transition of pancreatic intraepithelial neoplasm

    Yamaguchi Junpei, Yokoyama Yukihiro, Kokuryo Toshio, Ebata Tomoki, Enomoto Atsushi, Nagino Masato

    JOURNAL OF CLINICAL INVESTIGATION   Vol. 128 ( 8 ) page: 3619 - 3629   2018.8

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    DOI: 10.1172/JCI97755

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  109. Effectiveness of a modified 6-Fr endoscopic nasobiliary drainage catheter for patients with preoperative perihilar cholangiocarcinoma

    Kawashima Hiroki, Hirooka Yoshiki, Ohno Eizaburo, Ishikawa Takuya, Miyahara Ryoji, Watanabe Osamu, Hayashi Kazuhiko, Ishigami Masatoshi, Hashimoto Senju, Ebata Tomoki, Nagino Masato, Goto Hidemi

    ENDOSCOPY INTERNATIONAL OPEN   Vol. 6 ( 8 ) page: E1020 - E1030   2018.8

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  110. Impact of RAS/BRAF mutation status in locally advanced rectal cancer treated with preoperative chemotherapy

    Oshiro Taihei, Uehara Keisuke, Aiba Toshisada, Mukai Toshiki, Ebata Tomoki, Nagino Masato

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 23 ( 4 ) page: 681 - 688   2018.8

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  111. Ethanol ablation for refractory bile leakage after complex hepatectomy

    Ito A., Ebata T., Yokoyama Y., Igami T., Mizuno T., Yamaguchi J., Onoe S., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 8 ) page: 1036 - 1043   2018.7

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  112. Surgical resection for Bismuth type IV perihilar cholangiocarcinoma

    Ebata T., Mizuno T., Yokoyama Y., Igami T., Sugawara G., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 7 ) page: 829 - 838   2018.6

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    DOI: 10.1002/bjs.10556

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  113. Reappraisal of classification of distal cholangiocarcinoma based on tumour depth

    Aoyama H., Ebata T., Hattori M., Takano M., Yamamoto H., Inoue M., Asaba Y., Ando M., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 7 ) page: 867 - 875   2018.6

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  114. Impact of the gastrojejunal anatomic position as the mechanism of delayed gastric emptying after pancreatoduodenectomy

    Nojiri Motoi, Yokoyama Yukihiro, Maeda Takashi, Ebata Tomoki, Igami Tsuyoshi, Sugawara Gen, Yamaguchi Junpei, Nagino Masato

    SURGERY   Vol. 163 ( 5 ) page: 1063 - 1070   2018.5

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  115. Preoperative biliary colonization/infection caused by multidrug-resistant (MDR) pathogens in patients undergoing major hepatectomy with extrahepatic bile duct resection

    Sugawara Gen, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Yamaguchi Junpei, Mizuno Takashi, Yagi Tetsuya, Nagino Masato

    SURGERY   Vol. 163 ( 5 ) page: 1106 - 1113   2018.5

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  116. Efficacy of percutaneous transhepatic portal vein embolization using gelatin sponge particles and metal coils

    Komada Tomohiro, Suzuki Kojiro, Mizuno Takashi, Ebata Tomoki, Matsushima Masaya, Naganawa Shinji, Nagino Masato

    ACTA RADIOLOGICA OPEN   Vol. 7 ( 4 ) page: 2058460118769687   2018.4

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  117. Evolution of radical resection for perihilar cholangiocarcinoma.

    Sakata J, Ebata T, Wakai T

    Journal of hepato-biliary-pancreatic sciences   Vol. 25 ( 4 ) page: 249 - 251   2018.4

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    DOI: 10.1002/jhbp.534

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  118. Recurrence after curative-intent resection of perihilar cholangiocarcinoma: analysis of a large cohort with a close postoperative follow-up approach

    Komaya Kenichi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    SURGERY   Vol. 163 ( 4 ) page: 732 - 738   2018.4

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  119. Pre-exposure to Fluorouracil Increased Trifluridine Incorporation and Enhanced its Anti-tumor Effect for Colorectal Cancer

    Baba Taisuke, Kokuryo Toshio, Yamaguchi Junpei, Yokoyama Yukihiro, Uehara Keisuke, Ebata Tomoki, Nagino Masato

    ANTICANCER RESEARCH   Vol. 38 ( 3 ) page: 1427 - 1434   2018.3

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  120. Randomized clinical trial of adjuvant gemcitabine chemotherapy versus observation in resected bile duct cancer

    Ebata T., Hirano S., Konishi M., Uesaka K., Tsuchiya Y., Ohtsuka M., Kaneoka Y., Yamamoto M., Ambo Y., Shimizu Y., Ozawa F., Fukutomi A., Ando M., Nimura Y., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 105 ( 3 ) page: 192 - 202   2018.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/bjs.10776

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  121. Does the intestinal microenvironment have an impact on the choleretic effect of inchinkoto, a hepatoprotective herbal medicine?

    Uji Masahito, Yokoyama Yukihiro, Asahara Takashi, Ebata Tomoki, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    HEPATOLOGY RESEARCH   Vol. 48 ( 3 ) page: E303 - E310   2018.2

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  122. Cells of origin of pancreatic neoplasms

    Yamaguchi Junpei, Yokoyama Yukihiro, Kokuryo Toshio, Ebata Tomoki, Nagino Masato

    SURGERY TODAY   Vol. 48 ( 1 ) page: 9 - 17   2018.1

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  123. Outcomes of stage IV patients with colorectal cancer treated in a single institution: What is the key to the long-term survival?

    Mukai Toshiki, Uehara Keisuke, Aiba Toshisada, Nakamura Hayato, Ebata Tomoki, Nagino Masato

    JOURNAL OF THE ANUS RECTUM AND COLON   Vol. 2 ( 1 ) page: 16 - 24   2018.1

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  124. Duration of Antimicrobial Prophylaxis in Patients Undergoing Major Hepatectomy With Extrahepatic Bile Duct Resection: A Randomized Controlled Trial

    Sugawara Gen, Yokoyama Yukihiro, Ebata Tomoki, Mizuno Takashi, Yagi Tetsuya, Ando Masahiko, Nagino Masato

    ANNALS OF SURGERY   Vol. 267 ( 1 ) page: 142 - 148   2018.1

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  125. Application of fluorescent cholangiography during single-incision laparoscopic cholecystectomy for cholecystitis with a right-sided round ligament: Preliminary experience

    Nojiri Motoi, Igami Tsuyoshi, Toyoda Yoshitaka, Ebata Tomoki, Yokoyama Yukihiro, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    JOURNAL OF MINIMAL ACCESS SURGERY   Vol. 14 ( 3 ) page: 244 - 246   2018

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  126. Single-Incision Laparoscopic Splenectomy for an Unruptured Aneurysm of the Splenic Artery

    Toyoda Yoshitaka, Igami Tsuyoshi, Ochiai Yosuke, Ebata Tomoki, Yokoyama Yukihiro, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    MEDICAL PRINCIPLES AND PRACTICE   Vol. 27 ( 1 ) page: 95 - 98   2018

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  127. Uneven acute non-alcoholic fatty change of the liver after percutaneous transhepatic portal vein embolization in a patient with hilar cholangiocarcinoma - a case report

    Tsai Chun-Yi, Nojiri Motoi, Yokoyama Yukihiro, Ebata Tomoki, Mizuno Takashi, Nagino Masato

    BMC GASTROENTEROLOGY   Vol. 17 ( 1 ) page: 144   2017.12

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  128. Successful local treatment for repeated hepatic recurrences of cholangiolocellular carcinoma: a report on a long-term survivor.

    Shinohara K, Ebata T, Yokoyama Y, Igami T, Sugawara G, Mizuno T, Yamaguchi J, Shimoyama Y, Shiina S, Tateishi R, Arano T, Nagino M

    Surgical case reports   Vol. 3 ( 1 ) page: 120   2017.12

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  129. Long-term survival after multidisciplinary therapy for residual gallbladder cancer with peritoneal dissemination: a case report.

    Kuga D, Ebata T, Yokoyama Y, Igami T, Sugawara G, Mizuno T, Yamaguchi J, Nagino M

    Surgical case reports   Vol. 3 ( 1 ) page: 76   2017.12

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  130. Occult mucin-producing cholangiocarcinoma in situ: a rare clinical case with difficult tumour staging.

    Kiriyama M, Ebata T, Yokoyama Y, Igami T, Sugawara G, Mizuno T, Yamaguchi J, Nagino M

    Surgical case reports   Vol. 3 ( 1 ) page: 6   2017.12

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  131. Clinical influence of preoperative factor XIII activity in patients undergoing pancreatoduodenectomy

    Watanabe Nobuyuki, Yokoyama Yukihiro, Ebata Tomoki, Sugawara Gen, Igami Tsuyoshi, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    HPB   Vol. 19 ( 11 ) page: 972 - 977   2017.11

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  132. Pancreatoduodenectomy with portal vein resection for distal cholangiocarcinoma

    Maeta T., Ebata T., Hayashi E., Kawahara T., Mizuno S., Matsumoto N., Ohta S., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 104 ( 11 ) page: 1549 - 1557   2017.10

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  133. Loss of trefoil factor 1 inhibits biliary regeneration but accelerates the differentiation of hepatic progenitors into hepatocytes in mice

    Hayashi Yuki, Yamaguchi Junpei, Kokuryo Toshio, Ebata Tomoki, Yokoyama Yukihiro, Nagino Masato

    HEPATOLOGY   Vol. 66   page: 378A - 379A   2017.10

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    Web of Science

  134. Gemcitabine plus cisplatin and S-1 for biliary tract cancer: a single institute analysis

    Maeda Osamu, Shimokata Tomoya, Mizutani Takefumi, Inoue Megumi, Matsuoka Ayumu, Ota Akiko, Mizuno Takashi, Ebata Tomoki, Nagino Masato, Ando Yuichi

    ANNALS OF ONCOLOGY   Vol. 28   page: 50 - 50   2017.10

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  135. Profile of preoperative fecal organic acids closely predicts the incidence of postoperative infectious complications after major hepatectomy with extrahepatic bile duct resection: Importance of fecal acetic acid plus butyric acid minus lactic acid gap

    Yokoyama Yukihiro, Mizuno Takashi, Sugawara Gen, Asahara Takashi, Nomoto Koji, Igami Tsuyoshi, Ebata Tomoki, Nagino Masato

    SURGERY   Vol. 162 ( 4 ) page: 926 - 934   2017.10

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  136. The novel tumor suppressor Trefoil Factor Family 1 (TFF1) inhibits the development of hepatocellular carcinoma in mice

    Yamaguchi Junpei, Yokoyama Yukihiro, Kokuryo Toshio, Ebata Tomoki, Nagino Masato

    HEPATOLOGY   Vol. 66   page: 981A - 982A   2017.10

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  137. Clinicopathologic study on metachronous double cholangiocarcinomas of perihilar and subsequent distal bile duct origin

    Shinohara Kentaro, Shimoyama Yoshie, Ebata Tomoki, Yokoyama Yukihiro, Mizuno Takashi, Nakaguro Masato, Nagino Masato

    SURGERY   Vol. 162 ( 1 ) page: 84 - 93   2017.7

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  138. Phase II trial of neoadjuvant chemotherapy with S-1 and oxaliplatin plus bevacizumab for colorectal liver metastasis (N-SOG 05 trial)

    Mukai Toshiki, Uehara Keisuke, Goto Hidenari, Hiramatsu Kazuhiro, Kobayashi Satoshi, Sakamoto Eiji, Maeda Atsuyuki, Takeuchi Eiji, Okada Yoshito, Ebata Tomoki, Nagino Masato

    JAPANESE JOURNAL OF CLINICAL ONCOLOGY   Vol. 47 ( 7 ) page: 597 - 603   2017.7

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  139. Residual Carcinoma In Situ at the Ductal Stump has a Negative Survival Effect An Analysis of Early-stage Cholangiocarcinomas- -

    Tsukahara Tetsuo, Ebata Tomoki, Shimoyama Yoshie, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Nagino Masato

    ANNALS OF SURGERY   Vol. 266 ( 1 ) page: 126 - 132   2017.7

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  140. Portal Vein Bleeding after Pancreatectomy: Diagnosis and Stent Graft Repair - A Consecutive Case Series

    Suzuki Kojiro, Ebata Tomoki, Komada Tomohiro, Matsushima Masaya, Mizuno Takashi, Igami Tsuyoshi, Sugawara Gen, Yokoyama Yukihiro, Naganawa Shinji, Nagino Masato

    JOURNAL OF THE PANCREAS   Vol. 18 ( 4 ) page: 339 - 344   2017.7

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  141. Pulmonary Metastasis After Resection of Cholangiocarcinoma: Incidence, Resectability, and Survival

    Yamada Mihoko, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 41 ( 6 ) page: 1550 - 1557   2017.6

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  142. Study on the segmentation of the right anterior sector of the liver

    Kobayashi Tomoki, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    SURGERY   Vol. 161 ( 6 ) page: 1536 - 1542   2017.6

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  143. Perineal alveolar soft part sarcoma treated by laparoscopy-assisted total pelvic exenteration combined with pubic resection.

    Aiba T, Uehara K, Tsukushi S, Yoshino Y, Ebata T, Yokoyama Y, Igami T, Sugawara G, Nagino M

    Asian journal of endoscopic surgery   Vol. 10 ( 2 ) page: 198 - 201   2017.5

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  144. Recurrence after resection with curative intent for distal cholangiocarcinoma

    Komaya K., Ebata T., Shirai K., Ohira S., Morofuji N., Akutagawa A., Yamaguchi R., Nagino M.

    BRITISH JOURNAL OF SURGERY   Vol. 104 ( 4 ) page: 426 - 433   2017.3

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  145. The development of an automatically produced cholangiography procedure using the reconstruction of portal-phase multidetector-row computed tomography images: preliminary experience

    Hirose Tomoaki, Igami Tsuyoshi, Koga Kusuto, Hayashi Yuichiro, Ebata Tomoki, Yokoyama Yukihiro, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Mori Kensaku, Nagino Masato

    SURGERY TODAY   Vol. 47 ( 3 ) page: 365 - 374   2017.3

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  146. A Clear Difference Between the Outcomes After a Major Hepatectomy With and Without an Extrahepatic Bile Duct Resection

    Takagi Takehiro, Yokoyama Yukihiro, Kokuryo Toshio, Ebata Tomoki, Ando Masahiko, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 41 ( 2 ) page: 508 - 515   2017.2

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  147. Anatomic features of independent right posterior portal vein variants: Implications for left hepatic trisectionectomy

    Watanabe Nobuyuki, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    SURGERY   Vol. 161 ( 2 ) page: 347 - 354   2017.2

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  148. Adjuvant gemcitabine monotherapy for resectable perihilar cholangiocarcinoma with lymph node involvement: a propensity score matching analysis

    Mizuno Takashi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Yamaguchi Junpei, Nagino Masato

    SURGERY TODAY   Vol. 47 ( 2 ) page: 182 - 192   2017.2

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  149. Surgery-Related Muscle Loss and Its Association with Postoperative Complications After Major Hepatectomy with Extrahepatic Bile Duct Resection

    Otsuji Hidehiko, Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    WORLD JOURNAL OF SURGERY   Vol. 41 ( 2 ) page: 498 - 507   2017.2

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  150. Verification of the oncologic inferiority of percutaneous biliary drainage to endoscopic drainage: A propensity score matching analysis of resectable perihilar cholangiocarcinoma

    Komaya Kenichi, Ebata Tomoki, Yokoyama Yukihiro, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    SURGERY   Vol. 161 ( 2 ) page: 394 - 404   2017.2

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  151. Current Status on Cholangiocarcinoma and Gallbladder Cancer

    Ebata Tomoki, Ercolani Giorgio, Alvaro Domenico, Ribero Dario, Di Tommaso Luca, Valle Juan W.

    LIVER CANCER   Vol. 6 ( 1 ) page: 59 - 65   2017

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    DOI: 10.1159/000449493

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  152. Different Clinical Characteristics Between Distal Cholangiocarcinoma and Pancreatic Head Carcinoma With Biliary Obstruction

    Yokoyama Yukihiro, Ebata Tomoki, Igami Tsuyoshi, Sugawara Gen, Mizuno Takashi, Yamaguchi Junpei, Nagino Masato

    PANCREAS   Vol. 46 ( 10 ) page: 1322 - 1326   2017

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  153. Trefoil factor family 1 expression in the invasion front is a poor prognostic factor associated with lymph node metastasis in pancreatic cancer

    Sunagawa Masaki, Yamaguchi Junpei, Kokuryo Toshio, Ebata Tomoki, Yokoyama Yukihiro, Sugawara Gen, Nagino Masato

    PANCREATOLOGY   Vol. 17 ( 5 ) page: 782 - 787   2017

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  154. Current Status on Cholangiocarcinoma and Gallbladder Cancer. Invited Reviewed

    Ebata T, Ercolani G, Alvaro D, Ribero D, Di Tommaso L, Valle JW

    Liver Cancer   Vol. 6 ( 1 ) page: 59-65   2016.11

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  155. Surgical technique of hepatectomy combined with simultaneous resection of hepatic artery and portal vein for perihilar cholangiocarcinoma (with video). Invited Reviewed

    Ebata T, Ito T, Yokoyama Y, Igami T, Sugawara G, Mizuno T, Nagino M.

    J Hepatobiliary Pancreat Sci   Vol. 21 ( 8 ) page: E57-61   2014.8

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  156. *The concept of perihilar cholangiocarcinoma is valid Reviewed

    Ebata T,Kamiya J, ,Nishio H,Nagasaka T,Nimura Y,Nagino M

    Br J Surg   Vol. 96 ( 8 ) page: 926-934   2009.8

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  157. Perineural Invasion Is a Prognostic Factor in IntrahepaticCholangiocarcinoma Reviewed

    Kazuhisa Shirai, Tomoki Ebata, Koji Oda , Hideki Nishio , Tetsuro Nagasaka, Yuji Nimura ,Masato Nagino

    World J Surgery   Vol. 32 ( 9 ) page: 2395-2402   2008.9

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  158. *Pancreatic and duodenal invasion in distal bile duct cancer: paradox in the tumor classification of the American Joint Committee on Cancer Reviewed

    Ebata T, Nagino M, Nishio H, Igami T, Yokoyama Y, Nimura Y

    World Journal of Surgery   Vol. 31 ( 10 ) page: 2008-2015   2007.10

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  159. *Right hepatopancreatoduodenectomy: improvements over 23 years to attain acceptability Reviewed

    Ebata T, Nagino M, Nishio H, Arai T, Nimura Y

    J Hepatobiliary Pancreat Surg   Vol. 14 ( 2 ) page: 131-135   2007.3

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  160. 粘液産生胆管癌における表層拡大進展の外科病理 Invited Reviewed

    江畑智希、梛野正人、小田高司、西尾秀樹、伊神剛、横山幸浩、二村雄次

    消化器画像   Vol. 9 ( 3 )   2007

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  161. Anatomic right hepatic trisectionectomy (extended right hepatectomy) with caudate lobectomy for hilar cholangiocarcinoma Reviewed

    Nagino M, Kamiya J, Arai T, Nishio H, Ebata T, Nimura Y

    Annals of Surgery   Vol. 244   page: 706-714   2006

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  162. 肝門部胆管癌手術では尾状葉切除は必須か?-尾状葉胆管断端癌陰性の場合はどうか?- Invited

    西尾秀樹、梛野正人、新井利幸、江畑智希、湯浅典博、小田高司、二村雄次

    胆と膵   Vol. 26   page: 309-314   2006

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  163. 胆道癌の術前画像診断-治療医はなにを必要としているか?-A. MDCT診断 手術適応基準から考える胆道癌の読影ポイント Invited

    西尾秀樹、梛野正人、江畑智希、横山幸浩、伊神剛、千田嘉毅、杉浦禎一、二村雄次

    画像診断   Vol. 26   page: 544-553   2006

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  164. Ground Rounds 肝門部胆管癌 Invited

    西尾秀樹、梛野正人、横山幸浩、伊神剛、小田高司、湯浅典博、江畑智希、二村雄次

    消化器の臨床   Vol. 9   page: 353-364   2006

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  165. 門脈塞栓術の適応と方法のエビデンス Invited

    横山幸浩、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、伊神剛、二村雄次

    外科   Vol. 68   page: 415-420   2006

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  166. 肝がん治療のすべて:術前門脈塞栓併用肝切除術 Invited

    横山幸浩、梛野正人、小田高司、西尾秀樹、江畑智希、安部哲也、伊神剛、二村雄次

    肝胆膵   Vol. 53   page: 831-840   2006

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  167. 胆管内乳頭粘液性腫瘍(粘液産生胆管腫瘍) Invited

    伊神剛、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、横山幸浩、二村雄次

    消化器内視鏡   Vol. 18   page: 96-100   2006

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  168. 腹腔鏡下胆嚢摘出術の功罪 Invited

    伊神剛、梛野正人、湯浅典博、小田高司、西尾秀樹、江畑智希、横山幸浩、二村雄次

    消化器画像   Vol. 8   page: 209-215   2006

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  169. 肝内胆管・胆道の粘液産生腫瘍:膵での粘液産生腫瘍との比較を含めて Invited

    伊神剛、梛野正人、湯浅典博、小田高司、西尾秀樹、江畑智希、横山幸浩、二村雄次

    肝胆膵   Vol. 52   page: 193-204   2006

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  170. 胆嚢摘出術 Invited

    伊神剛、梛野正人、小田高司、西尾秀樹、江畑智希、横山幸浩、安部哲也、二村雄次

    外科   Vol. 68   page: 1561-1564   2006

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  171. 高齢者胆道癌の外科治療の意義 Invited

    深谷昌秀、梛野正人、西尾秀樹、小田高司、江畑智希、横山幸浩、伊神剛、二村雄次

    外科治療   Vol. 96   page: 930-932   2006

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  172. 膵管内乳頭粘液性腫瘍:本邦における現在の外科治療成績と予後 Invited

    高野学、江畑智希、梛野正人、新井利幸、西尾秀樹、二村雄次

    臨床消化器内科   Vol. 21   page: 233-238   2006

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  173. 肝門部胆管癌に対する肝左葉・尾状葉切除、門脈・肝動脈切除再建 Invited

    江畑智希、梛野正人、湯浅典博、西尾秀樹、白井量久、二村雄次

    手術   Vol. 60   page: 481-486   2006

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  174. 肝右葉切除術 Invited

    江崎稔、江畑智希、梛野正人、二村雄次

    手術   Vol. 60   page: 861-866   2006

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  175. Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: A randomized controlled trial Reviewed

    Sugawara G, Nagino M, Nishio H, Ebata T, Takagi K, Asahara T, Nomoto K, Nimura Y

    Annals of Surgery   Vol. 244   page: 796-714   2006

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  176. Hepatectomy for colorectal liver metastases with macroscopic intrabiliary tumor growth Reviewed

    Sugiura T, Nagino M, Oda K, Ebata T, Nishio H, Arai T, Nimura Y

    World Journal of Surgery   Vol. 30   page: 1902-1908   2006

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  177. Treatment of colorectawith biliary and portal vein tumor thrombi by hepatopancreatoduodenectomyl liver metastasis Reviewed

    Sugiura T, Nagino M, Ebata T, Arai T, Oda K, Yuasa N, Nimura Y

    Journal of Hepato-Biliary-Pancreatic Surgery   Vol. 13   page: 256-259   2006

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  178. Two hundred forty consecutive portal vein embolization before extended hepatectomy for biliary cancer: Surgical outcome and long-term survival Reviewed

    Nagino M, Kamiya J, Nishio H, Ebata T, Arai T, Nimura Y

    Annals of Surgery   Vol. 243   page: 364-372   2006

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  179. Clinicopathologic comparison of Siewert type II and III adenocarcinomas of the gastroesophageal junction Reviewed

    Yuasa N, Miyake H, Yamada T, Ebata T, Nimura Y,

    World Journal of Surgery   Vol. 30   page: 364-371   2006

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  180. Immunohistochemically demonstrated lymph node micrometastasis and prognosis in patients with gallbladder carcinoma Reviewed

    Sasaki E, Nagino M, Ebata T, Oda K, Arai T, Nishio H, Nimura Y

    Annals of Surgery   Vol. 244   page: 99-105   2006

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  181. One hundred consecutive hepatobiliary resections for biliary hilar malignancies: Preoperative blood donation, blood loss, transfusion, and outcome Reviewed

    Nagino M, Kamiya J, Arai T, Nishio H, Ebata T, Nimura Y

    Surgery   Vol. 137   page: 148-155   2005

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  182. 胆道癌に対する経皮経肝門脈枝塞栓術(PTPE)後の広範囲肝切除術 Invited

    小林聡、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、二村雄次

    臨床外科   Vol. 60   page: 31-37   2005

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  183. MD-CTによる肝門部における胆管内進展範囲の術前診断の検討 Invited

    千田嘉毅、梛野正人、西尾秀樹、湯浅典博、小田高司、新井利幸、江畑智希、二村雄次

    胆と膵   Vol. 25   page: 641-646   2005

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  184. 胆管癌切除例から見た術前期間の検討-平均在院日数の短縮 Invited

    千田嘉毅、梛野正人、西尾秀樹、湯浅典博、小田高司、新井利幸、江畑智希、二村雄次

    肝胆膵   Vol. 50   page: 495-498   2005

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  185. MD-CTによる肝門部胆管癌および中下部胆管癌における胆管内進展範囲の術前診断の検討 Invited

    千田嘉毅、梛野正人、西尾秀樹、湯浅典博、小田高司、新井利幸、江畑智希、二村雄次

    外科   Vol. 67   page: 1166-1171   2005

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  186. 胆管浸潤型肝内胆管癌の手術術式と治療成績:特に狭義の肝門部胆管癌との相違 Invited

    杢野泰司、江畑智希、梛野正人、新井利幸、西尾秀樹、二村雄次

    消化器画像   Vol. 7   page: 799-804   2005

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  187. 肝血流部分遮断時の肝血流動態、門脈枝塞栓術 Invited

    横山幸浩、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、二村雄次

    肝胆膵   Vol. 51   page: 451-460   2005

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  188. 右3区域、左3区域切除 Invited

    西尾秀樹、梛野正人、新井利幸、江畑智希、湯浅典博、小田高司、二村雄次

    外科   Vol. 67   page: 778-784   2005

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  189. 胆道癌 肝門部胆管癌の進展度診断と治療戦略 門脈浸潤の診断を中心に Invited

    杉浦禎一、江畑智希、西尾秀樹、新井利幸、梛野正人、二村雄次

    臨床消化器内科   Vol. 20   page: 1050-1056   2005

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  190. 胆管像による術前予測進展範囲をこえて進展した肝門部胆管癌の1例

    鈴村潔、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、二村雄次

    肝胆膵治療研究会誌   Vol. 3   page: 62-66   2005

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  191. 江畑智希、梛野正人、湯浅典博、新井利幸、西尾秀樹、二村雄次 Invited

    胆嚢癌に対する肝外胆管温存の肝十二指腸間膜郭清術

    手術   Vol. 59   page: 1281-1286   2005

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  192. 腫瘍などによる急性胆管炎に対する胆道ドレナージ(PTBD) Invited

    江畑智希、梛野正人、二村雄次

    Medicina   Vol. 42   page: 1283-1385   2005

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  193. PTCD Invited

    江畑智希、二村雄次、伊藤美千代、太田佳奈子

    JNNスペシャル 完全対応ドレーン・カテーテル管理   Vol. 77   page: 144-146   2005

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  194. Primary liver cancer with bidirectional differentiation into hepatocytes and biliary epithelium Reviewed

    Maeda A, Ebata T, Matsunaga K, Kanemoto H, Bando E, Yamaguchi S, Furukawa H, Uesaka K

    Journal of Hepato-Biliary-Pancreatic Surgery   Vol. 12   page: 484-487   2005

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  195. Omental flap in pancreaicoduodenectomy for protection of splanchnic vessels Reviewed

    Maeda A, Ebata T, Kanemoto H, Matsunaga K, Bando E, Yamaguchi S, Uesaka K

    World Journal of Surgery   Vol. 29   page: 1122-1126   2005

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  196. Yokoyama Y, Nagino M, Yuasa N, Oda K, Arai T, Nishio H, Ebata T, Nimura Y Reviewed

    Yokoyama Y, Nagino M, Yuasa N, Oda K, Arai T, Nishio H, Ebata T, Nimura Y

    Pancreas   Vol. 31   page: 192-194   2005

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  197. TNM classificaiton for perihilar cholangiocarcinoma: Comparison between 5th and 6th editoin of the AJCC/UICC staging system Reviewed

    Nishio H, Nagino M, Oda K, Ebata T, Arai T, NimuraY

    Langenbeck's Archives of Surgery   Vol. 390   page: 319-327   2005

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  198. 胆道外瘻により代謝性アシドーシスをきたした膵・胆管合流異常合併進行胆嚢癌の1例 Reviewed

    金本秀行、上坂克彦、前田敦行、江畑智希

    胆道   Vol. 18   page: 53-58   2004

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  199. 肝切除における門脈切除再建 Invited

    江畑智希、梛野正人、新井利幸、西尾秀樹、二村雄次

    消化器外科   Vol. 27   page: 1441-1449   2004

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  200. 胆嚢癌に対する肝区域切除・肝十二指腸靭帯郭清術 Invited

    江畑智希、梛野正人、二村雄次

    外科治療   Vol. 90   page: 600-607   2004

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  201. 肝門部胆管癌に再分類は必要か? Invited

    江畑智希、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、二村雄次

    外科治療   Vol. 90   page: 803-804   2004

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  202. 胆道疾患の新しい展開:胆道癌-肝門部胆管癌の手術成績- Invited

    梛野正人、新井利幸、西尾秀樹、江畑智希、湯浅典博、小田高司、二村雄次

    肝胆膵   Vol. 49   page: 357-361   2004

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  203. 肝臓外科-課題と対応-門脈枝塞栓術:方法、適応、治療成績 Invited

    梛野正人、西尾秀樹、新井利幸、江畑智希、湯浅典博、小田高司、二村雄次

    肝胆膵   Vol. 48   page: 191-194   2004

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  204. 典型例の画像と病理:胆道腫瘍胆管癌-肝門部・上部・中部・下部・広範囲 Invited

    西尾秀樹、梛野正人、小田高司、湯浅典博、新井利幸、江畑智希、二村雄次

    肝胆膵   Vol. 49   page: 633-643   2004

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  205. PMT由来浸潤癌と鑑別が問題となる通常型膵管癌の画像診断 Invited

    西尾秀樹、梛野正人、久米明倫、湯浅典博、小田高司、新井利幸、江畑智希、二村雄次

    消化器画像   Vol. 6   page: 45-52   2004

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  206. 肝胆膵癌のStaging Scoreと臨床評価。日本胆道外科研究会、胆道癌取扱い規約(第5版) Invited

    西尾秀樹、梛野正人、江畑智希、湯浅典博、小田高司、新井利幸、二村雄次

    肝胆膵   Vol. 48   page: 65-74   2004

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  207. 広範囲肝切除に対する経皮経肝門脈枝塞栓術(PTPE)の有用性 Invited

    小林聡、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、江畑智希、二村雄次

    日本外科学会雑誌   Vol. 105   page: 354-358   2004

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  208. 胆嚢癌手術を見直す至適リンパ節郭清の根拠-拡大リンパ節郭清- Invited

    広松孝、梛野正人、近藤哲、新井利幸、江畑智希、湯浅典博、小田高司、二村雄次

    胆と膵   Vol. 25   page: 175-178   2004

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  209. 原発性硬化性胆管炎の診断-原発性硬化性胆管炎における胆管造影所見- Invited

    広松孝、梛野正人、新井利幸、西尾秀樹、江畑智希、湯浅典博、小田高司、神谷順一、二村雄次

    消化器科   Vol. 39   page: 64-69   2004

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  210. 胆道出血 Invited

    前田敦行、上坂克彦、江畑智希、神谷順一、那野正人、湯浅典博、小田高司、新井利幸、二村雄次

    消化器画像   Vol. 6   page: 245-251   2004

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  211. Reverse latissimus dorsi flapによる横隔膜再建を行った1例 Reviewed

    中川雅裕、井上啓太、江畑智希、前田敦行、上坂克彦

    形成外科   Vol. 47   page: 541-545   2004

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  212. 高度進行胆嚢癌に対する積極的切除療法の意義 Invited

    上坂克彦、神谷順一、梛野正人、新井利行、西尾秀樹、江畑智希、前田敦行、松永和哉、金本秀行、伊在井淳子、二村雄次

    外科治療   Vol. 90   page: 805-806   2004

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  213. マイクロ波凝固療法術後の再発評価にFDG-PETが有用であった大腸癌肝転移の1例 Reviewed

    金本秀行、上坂克彦、伊在井淳子、前田敦行、江畑智希、古川敬芳

    日本臨床外科学会雑誌   Vol. 65   page: 175-179   2004

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  214. 診断に苦慮した進行大腸癌術後に発見された慢性C型肝炎合併胆管細胞癌の1例 Reviewed

    金本秀行、江畑智希、上坂克彦、前田敦行、松永和哉、伊在井淳子、古川敬芳、伊藤以知郎

    胆道   Vol. 18   page: 217-223   2004

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  215. 肝門部胆管癌と肝門浸潤をきたした肝内胆管癌の鑑別上の問題点 Invited

    江畑智希、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、二村雄次

    胆と膵   Vol. 25   page: 373-376   2004

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  216. 肝門部胆管癌の治療方針 Invited

    池山隆、江畑智希、二村雄次

    医学と薬学   Vol. 52   page: 877-883   2004

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  217. *Hepatectomy with portal vein resection for hilar cholangiocarcinoma: audit of 52 consecutive cases Reviewed

    Ebata T, Nagino M, Kamiya J, Uesaka K, Nagasaka T, Nimura Y

    Annals of Surgery   Vol. 238 ( 5 ) page: 720-727   2003.5

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  218. *Pathological appraisal of lines of resection for bile duct carcinoma Reviewed

    Ebata T, Watanabe H, Ajioka Y, Oda K, Nimura Y

    British Journal of Surgery   Vol. 89 ( 10 ) page: 1260-1267   2002.10

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Books 8

  1. Blumgart's surgery of the liver, biliary tract, and pancreas, 5th edition

    Tomoki Ebata, Masato Nagino( Role: Joint author)

    WB Saunders  2012 

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    Language:English

  2. 消化器外科学レビュー 2006 胆嚢炎・胆管炎

    江畑智希、梛野正人、二村雄次( Role: Joint author)

    2006 

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    Language:Japanese

  3. 膵癌・胆道癌の診断と治療  胆道癌治療の現状と展望

    江畑智希、二村雄次、梛野正人、新井利幸、西尾秀樹( Role: Joint author)

    2006 

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    Language:Japanese

  4. ナースの外科学、改訂4版肝臓の疾患

    江畑智希、金井道夫、二村雄次( Role: Joint author)

    中外医学者  2005 

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    Language:Japanese

  5. 消化器疾患診療実践ガイド 外科主要術式、胆嚢

    江畑智希、梛野正人、二村雄次( Role: Joint author)

    2005 

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    Language:Japanese

  6. 消化器外科学レビュー 2005 胆嚢炎・胆管炎

    江畑智希、梛野正人、二村雄次( Role: Joint author)

    2005 

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    Language:Japanese

  7. 消化器外科レビュー2004、胆嚢炎・胆管炎

    江畑智希、梛野正人、二村雄次( Role: Joint author)

    総合医学社  2004 

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    Language:Japanese

  8. 多職種チームのための周術期マニュアル 2 肝・胆・膵癌

    上坂克彦、前田敦行、江畑智希、金本秀行、山﨑はる江、望月裕美、岩崎すず子、武田裕美、大村ひとみ、小熊由美、柴本薫、森本直樹、福冨晃、新槙剛、山中真波、石川沙樹、内田冨美子、鈴木ルミ、尾上恵美、影山孝子、工藤綾子、佐藤和代、佐藤佳奈、戸塚規子( Role: Joint author)

    メヂカルフレンド  2004 

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    Language:Japanese

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Presentations 23

  1. Perihilar cholangiocarcinoma Expanding surgical indication improves survival

    Tomoki Ebata, Takashi Mizuno, Gen Sugawara, Tsuyoshi IgamiYukihiro Yokoyama, Jumpei Yamaguchi, Masahide Fukaya Keisuke Uehara, Kazushi Miyata, Toshio Kokuryo and Masato Nagino

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    Event date: 2015.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  2. Expanding surgical indication to locally advanced perihilar cholangiocarcinomain Nagoya University Hospital

    Tomoki Ebata, Takashi Mizuno, Gen Sugawara, Tsuyoshi Igami, Yukihiro Yokoyama, Jumpei Yamaguchi, Masahide Fukaya, Keisuke Uehara, Kazushi Miyata, and Masato Nagino

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    Event date: 2015.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  3. Preoperative biliary drainage for perihilar cholangiocarcinoma To do or not to do ? International conference

    Tomoki Ebata, Takashi Mizuno, Gen Sugawara, Tsuyoshi Igami, Yukihiro Yokoyama, Jumpei Yamaguchi, and Masato Nagino

    Asian-Pacific Hepato-Pancreato-Biliary Association 

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    Event date: 2015.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Singapore  

  4. Resection for Bismuth type IV Perihilar Cholangiocarcinoma International conference

    Tomoki Ebata, Takashi Mizuno, Gen Sugawara, Tsuyoshi Igami, Yukihiro Yokoyama, Jumpei Yamaguchi, and Masato Nagino

    Asian-Pacific Hepato-Pancreato-Biliary Association 

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    Event date: 2015.3

    Language:English   Presentation type:Oral presentation (general)  

    Country:Singapore  

  5. Resection for Perihilar Cholangiocarcinoma A Japanese approach for Bismuth type IV tumor International conference

    Ebata T, Nagino M

    Eastern & Western Association on Liver Tumors  

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    Event date: 2015.1

    Language:English   Presentation type:Oral presentation (general)  

    Country:Italy  

  6. 南周りの左尾状葉胆管枝をもつ症例に対する肝右葉・尾状葉+胆管切除

    江畑智希、加藤祐一郎、西尾秀樹、伊神剛、横山幸浩、菅原元、深谷昌秀、上原圭介、梛野正人

    日本肝胆膵外科学会・学術集会 

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    Event date: 2009.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  7. 肝門部胆管癌に対する肝切除術:合併症減少を目指す標準手技

    江畑智希、西尾秀樹、伊神剛、横山幸浩、菅原元、安部哲也、上原圭介、小田高司、梛野正人

    日本外科学会定期学術総会 

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    Event date: 2009.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  8. 名古屋大学第一外科グループにおける入局後の早期逸脱の実態

    日本臨床外科学会総会 

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    Event date: 2008.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  9. 肝門部胆管癌における肝側胆管断端追加切除の意義

    日本外科病理学会学術集会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  10. Pancreatic and Duodenal Invasion in Distal Bile Duct Cancer: Paradox in the Tumor classification of the American Joint Committiee on Cancer International conference

    World Congress of the International Hepato Pancreato Biliary Association 

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    Event date: 2008.2

    Language:English   Presentation type:Poster presentation  

  11. Bismuth I, II型肝門部胆管癌に対する切除方針

    江畑智希、池山隆、西尾秀樹、横山幸浩、伊神剛、二村雄次、梛野正人

    日本胆道学会学術集会 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  12. 中下部胆管癌における胆管切離線の設定

    江畑智希、梛野正人、伊神剛、西尾秀樹、横山幸浩、二村雄次

    日本外科学会定期学術集会 

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    Event date: 2007.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  13. 当科における膵空腸吻合手技

    日本臨床外科学会総会 

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    Event date: 2005.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  14. 肝門部胆管癌と肝門浸潤型肝内胆管癌の予後

    江畑智希、梛野正人、湯浅典博、新井利幸、西尾秀樹、二村雄次

    日本胆道学会学術集会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  15. 肝内胆管癌の外科治療成績

    江畑智希、梛野正人、湯浅典博、新井利幸、西尾秀樹、二村雄次

    日本消化器外科学会定期学術総会 

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    Event date: 2005.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  16. 胆道癌に対する肝右葉・尾状葉切除、肝外胆管切除術

    江畑智希、梛野正人、湯浅典博、新井利幸、西尾秀樹、二村雄次

    日本肝胆膵外科学会 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  17. 進行胆道癌に対する肝膵同時切除の成績

    江畑智希、梛野正人、湯浅典博、新井利幸、西尾秀樹、二村雄次

    日本外科学会定期学術集会 

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    Event date: 2005.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  18. Classification of hilar cholangiocarcinoma: Should intrahepatic cholangiocarcinoma be excluded? International conference

    Ebata T, Nagino M, Kamiya J, Arai T, Nishio H, Nimura Y

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    Event date: 2004.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  19. 肝門部胆管癌に対する外科治療の成績

    江畑智希、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、二村雄次

    日本消化器関連学会週間 

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    Event date: 2004.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  20. 肝門部胆管癌に対する門脈合併切除を要する肝切除

    江畑智希、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、二村雄次

    日本消化器外科学会定期学術総会 

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    Event date: 2004.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  21. 肝門部胆管癌における胆道再建の工夫

    江畑智希、梛野正人、湯浅典博、小田高司、新井利幸、西尾秀樹、二村雄次

    日本肝胆膵外科学会 

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    Event date: 2004.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  22. 肝門部胆管癌における肝切除例における門脈合併切除:組織学的門脈浸潤と予後との関連

    江畑智希、梛野正人、二村雄次

    日本消化器病学会総会 

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    Event date: 2004.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  23. 肝門部胆管癌における病期分類上の問題点

    江畑智希、梛野正人、神谷順一、西尾秀樹、湯浅典博、小田高司、新井利幸、二村雄次

    日本外科学会定期学術集会 

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    Event date: 2004.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

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KAKENHI (Grants-in-Aid for Scientific Research) 13

  1. 胆道癌肝切除における術後経過の視覚的解析手法と経過不良群予測システムの開発

    Grant number:23K08127  2023.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    江畑 智希

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    Authorship:Principal investigator 

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

  2. 胆道癌における融合型ノンコーディングRNAの機能解明と臨床応用

    Grant number:22K08820  2022.4 - 2025.3

    科学研究費助成事業  基盤研究(C)

    國料 俊男, 江畑 智希, 横山 幸浩, 山口 淳平, 砂川 真輝

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    Authorship:Coinvestigator(s) 

    融合型ノンコーディングRNA(融合型ncRNA)はタンパク合成をしないにもかかわらず、多くの遺伝子制御に関与し、生体内で重要な役割を果たしている。また融合遺伝子が癌の機能や制御に関与していることも報告されている。われわれは胆管癌での全ゲノム解析により、異なる2つのノンコーディングRNAからなる融合型ncRNAを十数種類同定した。融合型ncRNAの存在は未知のメカニズムの存在を示唆しており、融合遺伝子同様にノンコーディングRNAの機能不全や異常シグナルの活性化など癌化への関与が考えられる。融合型ncRNAの機能解析により関連遺伝子など未知の癌化メカニズムを解明し新規癌治療戦略を構築する。

  3. Whole genome sequencing concerning the chemoresistance of bile duct cancer

    Grant number:21K08796  2021.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Coinvestigator(s) 

  4. 消化器外科手術後感染性合併症を予防するプロバイオティクス製剤の開発

    Grant number:21K08731  2021.4 - 2024.3

    科学研究費助成事業  基盤研究(C)

    横山 幸浩, 山口 淳平, 渡辺 伸元, 江畑 智希, 國料 俊男

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    われわれは先行研究で、周術期にプロバイオティクスを使用することにより、術後感染性合併症発生が抑制されることを確認してきた。われわれがプロバイオティクスとして使用したものはLactobacillus casei ShirotaおよびBifidobacterium breve Yakultであったが、これらがプロバイオティクス製剤として最善のものであるかについては不明である。ヒトの腸内には術後感染性合併症をより強く抑制する菌が存在する可能性がある。本研究では、高度侵襲外科手術後の合併症を最も強力に抑制する腸内細菌種を、無菌マウスにヒトの腸内細菌叢を移植したモデルを用いて探索することを目的にする。
    本研究の目的は、高度侵襲消化器外科手術を受ける患者の術前を採集し、まず術後の感染合併症の発症と術前腸内細菌叢プロファイルの関連を探索することを第一としている。これまで名古屋大学医学部附属病院で、大量肝切除術、食道亜全摘術、膵頭十二指腸切除術、腹腔動脈幹合併切除を伴う膵体尾部切除術などを受ける患者から約500例の術前糞便検体を採集した。現在、これらの検体を解析し、糞便中有機酸濃度をHPLC法で、腸内細菌叢プロファイルを細菌特異的リボゾーマルRNAをターゲットにしたRT-PCR法で解析している。また、特定の検体に対しては次世代シーケンサーを用いて、さらに異なる視点からの菌叢解析も進めている。これらのデータと術後感染性合併症を含めた経過を表す様々な因子との相関を調べ、術前腸内細菌叢プロファイルと術後合併症発生との関連を調べている。一部の解析では、特定の便中有機酸濃度プロファイルが食道亜全摘術や、消化管再建を必要とする高度侵襲肝胆膵外科手術の術後感染性合併症と有意な相関があることを見出しており、このメカニズムを解明するためにさらに詳しく解析をすすめている。また、これらの解析から、特定の腸内細菌が術後の経過に及ぼす可能性についても探索してゆく予定である。最終的には、術前腸内細菌叢プロファイルを改善することにより、術後の感染性合併症をできるだけ減らし、周術期に使用する抗菌薬を可能な限り減らすことを目指す。今後もさらに糞便採集および便解析を進めてゆく予定である。
    症例の集積は順調に行なえており、並行して糞便の解析も行っている。まだ論文としては公表していないが、既に一部の結果を学会発表レベルで報告している。
    一部の解析で特定の便中有機酸濃度プロファイルが術後感染性合併症と有意な相関があることを見出しており、このメカニズムを解明するためにさらに詳しく解析をすすめている。本研究内容がさらに発展すれば、術前腸内細菌プロファイルを改善することにより、術後感染性合併症を減らすことができる可能性がある。最終的には、術前腸内環境を整えるための新規プロバイオティクス製剤開発が可能になるかもしれない。

  5. The mechanisms of early dissemination and tumor dormancy of pancreatic cancer

    Grant number:20H03751  2020.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

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    Authorship:Coinvestigator(s) 

  6. Novel treatment using adipose stem cell for postoperative liver damage

    Grant number:19K09118  2019.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    ONOE Shunsuke

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    Adipose stem cell sheets have no side effect, such as ascites retention or infection in the mouse model of 30% hepatectomy and partial hepatectomy. Angiogenesis was increased in the sheet in time dependent manner. A fluorescent-labeled human adipose stem cells were identified on the liver side of the mouse. Interestingly, a large number of mouse cells were observed in the human adipose stem cell sheet. These results suggest that bidirectional migration between human adipose stem cells and mouse cells is involved in liver regeneration using a human adipose stem cell sheet.

  7. Novel diagnostic methods for invisible pancreas cancer

    Grant number:19K09168  2019.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    WATANABE Nobuyuki

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    Exosomes isolated from KLM1 (human pancreatic cancer cell line), were involved in the proliferation and motility. Angiogenesis array revealed the several proteins concerning angiogenesis and motility in exosomes of KLM1. However, these proteins were not identified in bile exosomes. Since KLM1 is a cell line derived from human pancreatic cancer and bile is derived from biliary tract cancer patients, the results were considered to be due to the difference in cancer type. Although further investigation is required, the identified proteins may be markers of pancreatic cancer-specific exosomes.

  8. The role of Trefoil Factors in hepato-carcinogenesis

    Grant number:19K09141  2019.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Ebata Tomoki

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    Authorship:Principal investigator 

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    We found that TFF1 inhibited Wnt/b-catenin pathway and suppress the development of hepatocellular carcinoma. TFF1 inhibited the proliferative activity and promoted apoptosis of hepatocellular carcinoma cells in vitro, and TFF1-deficient mice developed frequent hepatocellular carcinoma. On the other hand, we found that TFF2 activated PTEN pathway and suppress the development of cholangiocellular carcinoma. TFF2 inhibited the proliferative activity and promoted apoptosis of cholangiocellular carcinoma cells, and TFF2-deficient mice developed frequent BilIN and cholangiocellular carcinoma. These results revealed that each TFF functioned as tumor suppressor in hepato-carcinogenesis.

  9. Novel therapy based on engraftment, asymmetric division and Self-organization of circulating tumor cells

    Grant number:19K09142  2019.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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  10. Novel nucleic acid medicine for the fusion genes in cholangiocarcinoma

    Grant number:18H02879  2018.4 - 2022.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    Nagino Masato

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    In the metachronous cholangiocarcinoma, the gene mutation in the secondary lesion has additional gene mutations to the gene mutation in the primary lesion, and their accumulations were considered to be one of the causes of the carcinogenesis in cholangiocarcinoma. Analysis of breakpoint on the coding region of the gene as somatic gene structure, demonstrated that total number is 3499 (3326-3655), the DEL (deletion) number is 2678 (2620-2781), the INV (inversion) number is 152 (136-170), INS (insertion) number 384 (364-406), DUP (tandem duplication) number 225 (192-253), and BND (breakend, interchromosomal translocation) number 58 (42-71). In addition, we revealed somatic structural variations on 320 genes, which detected in patients of the bile duct cancer in the GDC portal.
    These somatic structural variations were considered to be involved in the carcinogenesis of bile duct cancer.

  11. Novel therapy for cancer using deep ultraviolet

    Grant number:18K08673  2018.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    Miyata Kazushi

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    Deep UV (DUV) irradiation altered cell morphology and induced apoptosis in cancer cell lines. CHK1, TLK1, and MRE11 were involved in the cellular events, and suppression of TLK1 and MRE11 enhanced apoptosis by DUV irradiation. In xenograft mouse model, DUV treatment suppressed tumor growth. Administration of the TLK1 inhibitor enhanced the antitumor effect of DUV treatment and reduced the expression of Ki67 in the tumor. In DUV exposure to gastric mucosa of pig, defect and erosion were identified. However, healed after 1 week. There are no abnormalities in pathological examination or blood biochemical examination. Further investigation was required for clinical application. However, our results demonstrated efficiency of DUV irradiation in cancer. This study suggests novel therapies using deep UV irradiation for cancer.

  12. Development of real-time navigation system for hepatectomy

    Grant number:18K08644  2018.4 - 2021.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    IGAMI TSUYOSHI

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    We are going to try development of real-time navigation system for laparoscopic hepatectomy, which resembles a car navigation system. Mean FRE of initial 5 patients was 17.7mm (range, 12.2 to 24.3 mm). First improvement was that MDCT were taken using radiological markers for registration of body parts. Mean FRE of the 8 patients who utilized first improvement was 10.2mm (range, 6.5 to 16.5 mm) and decreased (p = 0.014). Second improvement was that a micro magnetic sensor as an intraoperative body position sensor was fixed on the right-sided chest wall and meant that pre- and post- operative FRE was similar due to an intraoperatively automatic correction of gap of body position. Preoperative and postoperative mean FRE of the 8 patients who utilized second improvement were 11.1mm (range, 9.6 to 13.9 mm) and 10.1mm (range, 6.0 to 12.2mm). Those mean FRE were statistically similar (p = 0.250).

  13. Analysis of the inhibitory effect of cysteine on liver damage

    Grant number:16K10567  2016.4 - 2019.3

    YOKOYAMA YUKIHIRO

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    Cysteine suppressed the shrinkage of hepatic stellate cells and strongly inhibited the endothelin-induced elevation of calcium in hepatic stellate cells. The serum ALT level in the cysteine-administered group was significantly lower than that in the non-administered group in a rat sepsis model. Cysteine showed an inhibitory effect on rat liver damage caused by intraperitoneal administration of lipopolysaccharide (LPS). The serum albumin level was correlated with the area of the psoas major muscle. The hospitalization period was prolonged, and postoperative complications such as an abdominal abscess and liver failure increased in patients with decreased muscle mass (sarcopenia) of the total femoral muscle. Most covalent bonds in cysteine were formed with serum albumin. Our results suggested that cysteine was effective in improving sarcopenia after surgery.

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Teaching Experience (On-campus) 3

  1. 胆道外科

    2021

  2. 腫瘍外科学セミナー

    2021

  3. 腫瘍外科実験研究

    2021

 

Social Contribution 12

  1. 肝門部領域胆管癌 外科治療の今

    Role(s):Lecturer

    2022.3

  2. 名古屋大学外科講座の現状と展望

    Role(s):Lecturer

    2022.3

  3. 胆道癌診療と漢方の可能性

    Role(s):Lecturer

    2021.12

  4. 名古屋大における肝門部胆管癌の取り組み

    Role(s):Lecturer

    2021.11

  5. 胆道癌の外科治療

    Role(s):Lecturer

    2021.10

  6. 胆道癌の集学的治療

    Role(s):Lecturer

    2021.10

  7. 胆道癌手術手技とそれを支える背景

    Role(s):Lecturer

    2021.10

  8. 胆管がんのドレナージと外科治療

    Role(s):Lecturer

    愛知県医師会  2021.8

  9. 肝門部胆管癌手術

    Role(s):Advisor, Demonstrator

    2021.7

  10. これからの外科医へのメッセージ

    Role(s):Lecturer, Organizing member

    2021.6

  11. 肝門部胆管癌の治療戦略

    Role(s):Lecturer

    2021.6

  12. 肝門部胆管癌の治療成績向上のために

    Role(s):Lecturer

    2021.4

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