Faculty Profiles - SATAKE, Hiroko

Papers - SATAKE, Hiroko

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RVS技術の乳腺領域への臨床応用:非触知病変に対する有用性

澤木明子, 佐竹弘子, 石垣聡子, 石垣武男, 島本佳寿広, 小田高司, 今井常夫, 長坂徹朗, 荒井修, 三竹毅

超音波医学 Vol. 33 page： S294 2006

16列マルチスライスCTによる膵頭部のCT arteriographyにおける画像作成条件の検討

石垣聡子, 伊藤茂樹, 鈴木耕次郎, 佐竹弘子, 池田充, 石垣武男

日本医学放射線学会 page： S296 2006

Real Virtual Sonography(RVS)を用いた乳房温存術ナビゲーションシステムの開発

佐竹弘子, 澤木明子, 石垣聡子, 福原理恵子, 島本佳寿広, 今井常夫, 小田高司, 菊森豊根, 石垣武男

日本乳癌学会総会プログラム抄録集 Vol. 203 2006

乳癌の拡がり診断　RVS(Real-time Virtual Sonography)によるUSとCTの対比

澤木明子, 佐竹弘子, 石垣聡子, 福原理恵子, 石垣武男, 島本佳寿広, 小田高司, 菊森豊根, 今井常夫, 長坂徹郎

日本乳癌学会総会プログラム抄録集 Vol. 271 2006

【超音波画像診断の最新技術と臨床活用　最新技術をキーワードで斬る】 RVS　RVS(Real-time Virtual Sonography)技術の乳腺領域への臨床応用

佐竹弘子, 澤木明子, 長縄慎二, 三竹毅, 荒井修

DIGITAL MEDICINE Vol. 6 page： 56-59 2006

Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)

RVS(Real-time Virtual Sonography)は、取得しておいたCTデータからUS走査に同期させてCTMPR画像を並列描画させるシステムである。乳腺の画像診断における有用性が高く、従来同定できなかった乳癌の検出に有効的新技術と考える。

Intra- and Interobserver Agreement and Performance Score of Breast Phantom ImageInterpretation:Influence of Ambient Room Lighting Levels

Kazuyuki Koyama,Kazuhiro Shimamoto,Mitsuru Ikeda,Hideyuki Muramoto,Hiroko Satake,Akiko Sawaki,Katsuhiko Kato,Hiromichi Fukushima, Takeo Ishigaki

Nagoya J.Med.Sci. Vol. 68 page： 147-153 2006

Diagnostic value of curved multiplanar reformatted images in multislice CT for the detection of resectable pancreatic ductal adenocarcinoma.

Fukushima H, Itoh S, Takada A, Mori Y, Suzuki K, Sawaki A, Iwano S, Satake H, Ota T, Ikeda M, Ishigaki T

Eur Radiol Vol. 16 page： 1709-1718 2006

The effect of patient age on contrast enhancement during CT of the pancreatobiliary region.

Itoh S, Ikeda M, Satake H, Ota T, Ishigaki T

AJR Am J Roentgenol Vol. 187 page： 505-510 2006

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The objective of our study was to assess whether it is possible to reduce the dose and rate of contrast material injection in elderly patients in triple-phase contrast-enhanced CT of the pancreatobiliary region with an MDCT scanner. SUBJECTS AND METHODS: One hundred twelve patients were divided into three groups: contrast injection at 0.08 mL/kg body weight/s (an upper limit of 5 mL/s) over 30 seconds in patients 60 years old or younger (group 1, n = 49), the same contrast injection as group 1 in patients more than 60 years old (group 2, n = 32), and contrast injection at 0.07 mL/kg body weight/s (an upper limit of 4.5 mL/s) over 30 seconds in patients more than 60 years old (group 3, n = 31). Contrast enhancement in the aorta, portal venous system, pancreas, and liver was assessed quantitatively. Two radiologists blinded to the patients' clinical information and the injection protocol used to acquire the CT images graded the degree of contrast enhancement using a 5-point scoring system. The results for the different groups were statistically compared. RESULTS: Contrast enhancement in the main phases for all organs was significantly more intense in group 2 than in groups 1 and 3. Cases in which pancreatic enhancement in the pancreatic phase was graded as excessive were more frequently observed in group 2. No statistically significant differences were observed between groups 1 and 3 in either quantitative or visual assessment for enhancement of any organ in any phase. CONCLUSION: We recommend reducing the dose and rate of contrast material injection by at least 10% for elderly patients undergoing MDCT examination of the pancreatobiliary region.

Assessment of anomalous pancreaticobiliary ductal junction with high-resolution multiplanar reformatted images in MDCT.

Itoh S, Fukushima H, Takada A, Suzuki K, Satake H, Ishigaki T

AJR Am J Roentgenol Vol. 187 page： 668-675 2006

Language：English Publishing type：Research paper (scientific journal)

OBJECTIVE: The objective of our study was to assess the capabilities of MDCT for the diagnosis of an anomalous pancreaticobiliary ductal junction using high-resolution multiplanar reformatted (multiplanar reconstruction) images. MATERIALS AND METHODS: This study included nine patients with and 54 without an anomalous pancreaticobiliary ductal junction confirmed on direct cholangiopancreatography. Multiplanar reconstruction images with 0.5-mm continuous slices were generated from isotropic or nearly isotropic pancreatic phase images. By mainly interpreting the multiplanar reconstruction images using the Scrolling mode, two blinded reviewers independently determined whether the confluence of the pancreatic and biliary ducts joined in the pancreatic parenchyma (in other words, outside the duodenal wall). The results were correlated with the findings of direct cholangiopancreatography. The diagnostic capabilities of CT for revealing associated pancreatobiliary diseases were assessed in patients with this anomaly. RESULTS: Interobserver agreement in the classification of the duct confluence was high (kappa = 0.804). The duct confluence was identified in all patients except four without an anomalous pancreaticobiliary ductal junction. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CT for diagnosing an anomalous pancreaticobiliary ductal junction were 100% (9 of 9 patients), 87% (47 of 54 patients), 89% (56 of 63 patients), 75% (9 of 12 patients), and 100% (47 of 47 patients) in the final decisions, respectively. CT showed all associated pancreatobiliary diseases except bile duct stones in two patients. CONCLUSION: MDCT enabled the diagnosis of an anomalous pancreaticobiliary ductal junction by showing whether the pancreatic and biliary ducts join within the pancreatic parenchyma on high-resolution multiplanar reconstruction images.

CT depiction of small arteries in the pancreatic head: assessment using coronal reformatted images with 16-channel multislice CT.

Ishigaki S, Itoh S, Satake H, Ota T, Ishigaki T

Abdom Imaging Vol. 32 page： 215-223 2006

Three-phase CT examination of the pancreatobiliary region using multislice CT with 1-mm collimation.

Itoh S, Suzuki K, Iwano S, Satake H, Ota T, Ikeda M, Ishigaki T

Radiat Med Vol. 23 page： 283-291 2005

造影3D-CTガイド下の乳腺部分切除術におけるVideo Assisted Thoracoscopic Surgery marker使用経

小田高司, 加藤雅通, 亀井桂太郎, 加藤万事, 窪田智行, 椰野正人, 佐竹弘子, 澤木明子, 石垣武男, 二村雄次

日本乳癌学会総会プログラム抄録集 Vol. 264 2005

Branch duct-type intraductal papillary mucinous tumor: diagnostic value of multiplanar reformatted images in multislice CT.

Takada A, Itoh S, Suzuki K, Iwano S, Satake H, Ota T, Ikeda M, Ishigaki T

Eur Radiol Vol. 15 page： 1888-1897 2005

Language：English Publishing type：Research paper (scientific journal)

The object of this study was to evaluate the usefulness of high-resolution multiplanar reformatted (MPR) images obtained by multislice CT in demonstrating connection between pancreatic cystic lesions and the main pancreatic duct. The study included 27 lesions with connection to the main pancreatic duct and 12 lesions without. All but one of the former lesions were branch duct-type intraductal papillary mucinous tumors (IPMTs). Oblique and curved MPR images with 0.5 mm continuous slices were generated from pancreatic-phase axial images reconstructed with 0.5 mm or 1 mm thickness at 0.5 mm intervals over a 260 mm field of view. The diagnostic capabilities for demonstrating connection with the main pancreatic duct were compared among axial images, MPR images, and both axial and MPR images in combination using the Brier score. The diagnosis in MPR images for demonstrating connection was more certain than that in axial images (P<0.05). Compared with MPR images alone, the use of both axial and MPR images resulted in further improvements in diagnostic performance, although the difference was not statistically significant. The use of high-resolution MPR images significantly improves diagnostic performance for demonstrating connection between pancreatic cystic lesions and the main pancreatic duct, which is useful for the diagnosis of branch duct-type IPMT.

Multiphase contrast-enhanced CT of the liver with a multislice CT scanner: effects of iodine concentration and delivery rate.

Itoh S, Ikeda M, Achiwa M, Satake H, Ota T, Ishigaki T

Radiat Med Vol. 23 page： 61-69 2005

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To determine whether or not high-concentration contrast material is useful in multiphase contrast-enhanced CT of the liver with a multislice CT scanner. MATERIALS AND METHODS: One hundred twenty-four examinations, in which first- and second-pass acquisitions (double arterial phase imaging) were performed during a single breath-hold followed by third-pass acquisition, were randomized into three protocols: contrast injection at 0.07 mL/kg body weight/sec over 30 sec at an iodine concentration of 300 mgI/mL in group 1, contrast injection at 0.06 mL/kg body weight/sec over 30 sec at an iodine concentration of 350 mgI/mL in group 2, and contrast injection at 0.07 mL/kg body weight/sec over 25.7 sec at an iodine concentration of 350 mgI/mL in group 3. Each group received an equivalent iodine dose per kg body weight (2.1 mL/kg of contrast material of 300 mgI/mL). Contrast enhancement in each acquisition was measured in the aorta, portal vein, and liver. RESULTS: No statistically significant differences were seen between groups 1 and 2 in any enhancement in any acquisition. In group 3, aortic enhancement in the first-pass acquisition was significantly more intense than in groups 1 and 2, while portal venous enhancement and hepatic enhancement were equivalent. CONCLUSION: Shortening the injection duration for a given iodine dose with high-concentration contrast material (group 3) can achieve improved arterial enhancement on arterial phase images.

Diagnostic value of multislice computed tomography for pancreas divisum: assessment with oblique coronal reconstruction images.

Itoh S, Takada A, Satake H, Ota T, Ishigaki T

J Comput Assist Tomogr Vol. 29 page： 452-460 2005

Multi-slice CT of thyroid nodules: comparison with ultrasonography.

Ishigaki S, Shimamoto K, Satake H, Sawaki A, Itoh S, Ikeda M, Ishigaki T, Imai T

Radiat Med Vol. 22 page： 346-353 2004

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To evaluate the usefulness of multi-slice computed tomography (MSCT) in comparison with ultrasonography (US) for the differentiation of benign from malignant thyroid nodules and the evaluation of tumor extension. MATERIALS AND METHODS: Thirty patients with thyroid nodules (14 malignant, 16 benign) who underwent both MSCT and US participated in the present study. MSCT with contrast enhancement was performed, and 3D shaded volume rendering (SVR) and multiplanar reconstruction (MPR) were employed to differentiate benign from malignant nodules and to evaluate tumor extension. US images were obtained using a 7.5 MHz annular array probe. A three-point rating scale was used for image interpretation, and the kappa statistic was employed to evaluate agreement between MSCT and US. RESULTS: Sensitivity in differentiating benign from malignant nodules was found to be 85.7% for US and 78.6% for MSCT. Disagreement between MSCT and US occurred in assessing the homogeneity of the solid component and the presence of fibrous capsule. In two of seven T4 cases, MPR provided a more accurate diagnosis than US examination in detecting extracapsular invasion. CONCLUSION: For differential diagnosis of thyroid nodules, US was found to be better than MSCT. However, MSCT could be useful for the evaluation of advanced cases with suspicion of extracapsular extension.

Late-arterial and portal-venous phase imaging of the liver with a multislice CT scanner in patients without circulatory disturbances: automatic bolus tracking or empirical scan delay?

Itoh S, Ikeda M, Achiwa M, Satake H, Iwano S, Ishigaki T

Eur Radiol Vol. 14 page： 1665-1673 2004

Language：English Publishing type：Research paper (scientific journal)

The value of automatic bolus tracking in late-arterial and portal-venous phase imaging of the liver with a multislice CT scanner as compared with fixed time-delay examination in patients without circulatory disturbances is evaluated. For the evaluation of known or suspected liver disease, 98 multiphase contrast-enhanced CT examinations including double late-arterial phase imaging were randomized into either scanning with a scan delay of 30 s from the beginning of contrast material injection or scanning with automatic bolus tracking. Contrast material was injected at 0.07 ml/kg body weight/s over 30 s. Contrast enhancement in each acquisition was measured in the aorta, portal vein, liver, pancreas and hepatocellular carcinomas. The density difference between hepatocellular carcinomas and the hepatic parenchyma was calculated. The mean time to the first-pass acquisition as determined by automatic bolus tracking was 29.6 s. No statistically significant difference was observed between the two groups either in any enhancement in any acquisition or in the lesion-to-liver density difference. The use of automatic bolus tracking in late-arterial and portal-venous phase hepatic CT does not significantly improve the degree of contrast enhancement in the aorta, portal vein, liver and pancreas or lesion-to-liver conspicuity in patients without circulatory disturbances.

Solitary pulmonary nodules: optimal slice thickness of high-resolution CT in differentiating malignant from benign.

Iwano S, Makino N, Ikeda M, Itoh S, Tadokoro M, Satake H, Ishigaki T

Clin Imaging Vol. 28 page： 322-328 2004

Evaluation of abdominal aortic aneurysm for endovascular stent-grafting with volume-rendered CT images of vessel lumen and thrombus.

Fukuhara R, Ishiguchi T, Ikeda M, Ota T, Takai K, Satake H, Ishigaki T

Radiat Med Vol. 22 page： 332-341 2004

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To evaluate the accuracy of CT images of abdominal aortic aneurysm (AAA) with volume-rendered (VR) display of vessel lumen and thrombus and to evaluate its usefulness in the planning of stent-grafting. MATERIALS AND METHODS: Helical CT was performed in 11 patients with AAA. Volume data of the vessel lumen and thrombus were separately extracted, and the VR images were reconstructed. Vessel measurements were made by five radiologists and compared with the axial and multiplanar reconstruction (MPR) images. Angiography and intravascular ultrasonography were used as standard references. The relations of aneurysmal sac to the major arterial branches and the subjective overall diagnostic value were evaluated by using a continuous rating scale. RESULTS: Accuracy of measurements was higher on VR images than on axial/MPR in 7 of 13 regions. Interobserver variance of VR images was smaller in 7 of 14 regions. Detection of renal and internal iliac artery involvements was better on VR images (p<0.05). Overall diagnostic value was also higher on VR images (p<0.05). CONCLUSION: VR CT images of vessel lumen and thrombus are supportive of and supplementary to conventional axial/MPR images in planning stent-grafting for AAA.

Usefulness of a method for changing tube current during helical scanning in multislice CT.

Kojima M, Itoh S, Ikeda M, Satake H, Koyama S, Aoyama T, Watanabe N, Ishigaki T

Radiat Med Vol. 21 page： 193-204 2003

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To determine whether employing a method for changing the tube current during helical scanning helps to adapt the image noise among various sections of the upper abdomen and chest in multislice computed tomography (CT). MATERIALS AND METHODS: One hundred CT examinations of the upper abdomen were assigned to one of two scanning protocols: standard scanning with a constant tube current and scanning with the changing method based on protocol 1. One hundred fifty CT examinations of the chest were assigned to one of three protocols: standard scanning with a constant tube current and scanning with the changing method based on protocols 1 and 2. In protocol 1, the tube current for each rotation was reduced in proportion to the water equivalent thickness based on the rotation showing the maximum value, while, in protocol 2, the tube current was increased in proportion to the water equivalent thickness based on the rotation showing the minimum value. The mean tube current, mean standard deviations (SDs) of the measured CT numbers, and dispersion of the SDs were compared between the different protocols. RESULTS: In the upper abdomen, the use of the changing method based on protocol 1 resulted in a significant reduction in the dispersion of the SDs of CT numbers, with no increase in mean tube current or mean SDs. In the chest, use of the changing method based on protocol 2 resulted in a significant reduction in the dispersion of the SDs of CT numbers, with a reduction in mean tube current and no increase in mean SDs. CONCLUSION: The method for changing tube current during helical scanning makes it possible to adapt the image noise among various sections of the upper abdomen and chest without increasing dose in multislice CT.

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Papers - SATAKE, Hiroko