研究者詳細 - 清井　仁

論文 - 清井　仁

分割表示 >> ／全件表示 324 件中 1 - 324 件目

A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells with FLT3 mutations. 査読有り

Yamaura T, Nakatani T, Uda K, Ogura H, Shin W, Kurokawa N, Saito K, Fujikawa N, Date T, Takasaki M, Terada D, Hirai A, Akashi A, Chen F, Adachi Y, Ishikawa Y, Hayakawa F, Hagiwara S, Naoe T, Kiyoi H.

Blood 2017年11月

Development and analysis of patient-derived xenograft mouse models in intravascular large B-cell lymphoma. 査読有り

Shimada K, Shimada S, Sugimoto K, Nakatochi M, Suguro M, Hirakawa A, Hocking TD, Takeuchi I, Tokunaga T, Takagi Y, Sakamoto A, Aoki T, Naoe T, Nakamura S, Hayakawa F, Seto M, Tomita A, Kiyoi H.

Leukemia. 30 巻 ( 7 ) 頁： 1568-79 2016年7月

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. 査読有り

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 48 巻 ( 5 ) 頁： 569-74 2016年5月

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients. 査読有り

Kihara R, Nagata Y, Kiyoi H, Kato T, Yamamoto E, Suzuki K, Chen F, Asou N, Ohtake S, Miyawaki S, Miyazaki Y, Sakura T, Ozawa Y, Usui N, Kanamori H, Kiguchi T, Imai K, Uike N, Kimura F, Kitamura K, Nakaseko C, Onizuka M, Takeshita A, Ishida F, Suzushima H, Kato Y, Miwa H, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Naoe T.

Leukemia 28 巻頁： 1586-1595 2014年

Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation. 査読有り

Yasuda T, Ueno T, Fukumura K, Yamato A, Ando M, Yamaguchi H, Soda M, Kawazu M, Sai E, Yamashita Y, Murata M, Kiyoi H, Naoe T, Mano H.

Leukemia 28 巻頁： 426-428 2014年

Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment. 査読有り

Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.

Blood 118 巻頁： 1600-1609 2011年

KW-2449, a novel multi-kinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation. 査読有り

Shiotsu Y*, Kiyoi H*, Ishikawa Y, Tanizaki R, Shimizu M, Umehara H, Ishii K, Mori Y, Ozeki K, Minami Y, Abe A, Maeda H, Akiyama T, Kanda Y, Sato Y, Akinaga S, Naoe T.

Blood 114 巻頁： 1607-1617 2009年

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies 査読有り

Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Saito K, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Saito H, Ueda R, Ohno R, and Naoe T.

Blood 97 巻頁： 2434-2439 2001年

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. 査読有り

Kiyoi H, Naoe T, Nakano Y, Yokota S, Minami S, Miyawaki S, Asou N, Kuriyama K, Jinnai I, Shimazaki C, Akiyama H, Saito K, Oh H, Motoji T, Omoto E, Saito H, Ohno R, Ueda R.

Blood 93 巻頁： 3074-3080 1999年

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. 査読有り

Kiyoi H, Towatari M, Yokota S, Hamaguchi M, Ohno R, Saito H, Naoe T.

Leukemia 12 巻頁： 1333-1337 1998年

Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells 査読有り国際誌

Kawashima Naomi, Ishikawa Yuichi, Kim Jeong Hui, Ushijima Yoko, Akashi Akimi, Yamaguchi Yohei, Hattori Hikaru, Nakashima Marie, Ikeno Seara, Kihara Rika, Nishiyama Takahiro, Morishita Takanobu, Watamoto Koichi, Ozawa Yukiyasu, Kitamura Kunio, Kiyoi Hitoshi

NATURE COMMUNICATIONS 13 巻 ( 1 ) 頁： 1624 2022年3月

Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma 査読有り国際誌

Shimada Kazuyuki, Yoshida Kenichi, Suzuki Yasuhiro, Iriyama Chisako, Inoue Yoshikage, Sanada Masashi, Kataoka Keisuke, Yuge Masaaki, Takagi Yusuke, Kusumoto Shigeru, Masaki Yasufumi, Ito Takahiko, Inagaki Yuichiro, Okamoto Akinao, Kuwatsuka Yachiyo, Nakatochi Masahiro, Shimada Satoko, Miyoshi Hiroaki, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Shiozawa Yusuke, Nannya Yasuhito, Okabe Asako, Kohno Kei, Atsuta Yoshiko, Ohshima Koichi, Nakamura Shigeo, Ogawa Seishi, Tomita Akihiro, Kiyoi Hitoshi

BLOOD 137 巻 ( 11 ) 頁： 1491 - 1502 2021年3月

Allogeneic hematopoietic stem cell transplantation at the first remission for younger adults withFLT3-internal tandem duplication AML: The JALSG AML209-FLT3-SCT study 査読有り国際誌

Kawashima, N; Ishikawa, Y; Atsuta, Y; Sawa, M; Ozawa, Y; Hayashi, M; Kohno, A; Tomita, A; Maeda, T; Sakaida, E; Usuki, K; Hagihara, M; Kanamori, H; Matsuoka, H; Kobayashi, M; Asou, N; Ohtake, S; Matsumura, I; Miyazaki, Y; Naoe, T; Kiyoi, H

CANCER SCIENCE 111 巻 ( 7 ) 頁： 2472 - 2481 2020年7月

Simple and early prediction of severe CAR-T-related adverse events after Axi-cel infusion by initial high fever. 査読有り国際誌

Wakabayashi H, Terakura S, Ishigiwa K, Ohara F, Hirano S, Yokota H, Kuwano S, Furukawa K, Shimada K, Sato T, Hanajiri R, Kiyoi H

International journal of hematology 2025年2月

Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): long-term results of a multicentre, single-arm, phase 2 trial 査読有り国際誌

Shimada, K; Yamaguchi, M; Kuwatsuka, Y; Matsue, K; Sato, K; Kusumoto, S; Nagai, H; Takizawa, J; Fukuhara, N; Nagafuji, K; Miyazaki, K; Ohtsuka, E; Okamoto, A; Sugita, Y; Uchida, T; Kayukawa, S; Wake, A; Ennishi, D; Kondo, Y; Meguro, A; Kin, Y; Minami, Y; Hashimoto, D; Nishiyama, T; Shimada, S; Masaki, Y; Okamoto, M; Atsuta, Y; Kiyoi, H; Suzuki, R; Nakamura, S; Kinoshita, T; Ennishi, D; Kondo, Y; Meguro, A; Kin, Y; Minami, Y; Hashimoto, D; Nishiyama, T; Shimada, S; Masaki, Y; Okamoto, M; Atsuta, Y; Kiyoi, H; Suzuki, R; Nakamura, S; Kinoshita, T

ECLINICALMEDICINE 80 巻頁： 103078 2025年2月

Post-transplant TKIs for Ph+ ALL: practices to date and clinical significance. 査読有り国際誌

Nishiwaki S, Terakura S, Morishita T, Goto T, Inagaki Y, Miyao K, Fukushima N, Hirano D, Tange N, Kurahashi S, Kuwatsuka Y, Kasai M, Iida H, Ozeki K, Sawa M, Nishida T, Kiyoi H

International journal of hematology 2025年1月

Sustained inhibition of CSF1R signaling augments antitumor immunity through inhibiting tumor-associated macrophages 査読有り国際誌

Sato, T; Sugiyama, D; Koseki, J; Kojima, Y; Hattori, S; Sone, K; Nishinakamura, H; Ishikawa, T; Ishikawa, Y; Kato, T; Kiyoi, H; Nishikawa, H

JCI INSIGHT 10 巻 ( 1 ) 2025年1月

Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway 査読有り国際共著国際誌

Adachi, Y; Terakura, S; Osaki, M; Okuno, Y; Sato, Y; Sagou, K; Takeuchi, Y; Yokota, H; Imai, K; Steinberger, P; Leitner, J; Hanajiri, R; Murata, M; Kiyoi, H

NATURE COMMUNICATIONS 15 巻 ( 1 ) 頁： 10376 2024年12月

Nelarabine-combined chemotherapy improves outcome of T-cell acute lymphoblastic leukemia but shows more severe neurotoxicity: JALSG T-ALL213-O 査読有り国際誌

Hayakawa, F; Mori, N; Imai, K; Yokoyama, Y; Katsuoka, Y; Saito, T; Murayama, T; Yamazaki, E; Sato, S; Atsuta, Y; Ishikawa, Y; Sakaida, E; Hatta, Y; Matsumura, I; Miyazaki, Y; Kiyoi, H

CANCER SCIENCE 2024年11月

Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan 査読有り国際誌

Sugimoto, Y; Nagaharu, K; Ohya, E; Ohishi, K; Tawara, I; Ito, T; Gotoh, A; Nakamae, M; Kimura, F; Koike, M; Kirito, K; Wada, H; Usuki, K; Tanaka, T; Mori, T; Wakita, S; Saito, TI; Saito, AM; Shimoda, K; Kurokawa, T; Tomita, A; Edahiro, Y; Hashimoto, Y; Kiyoi, H; Akashi, K; Matsumura, I; Takenaka, K; Komatsu, N

INTERNATIONAL JOURNAL OF HEMATOLOGY 120 巻 ( 6 ) 頁： 684 - 693 2024年10月

Misleading antigenic von Willebrand factor levels in acquired von Willebrand syndrome secondary to monoclonal gammopathy of undetermined significance 査読有り国際誌

Okamoto, S; Suzuki, A; Tamura, S; Suzuki, N; Kanematsu, T; Suzuki, N; Kawaguchi, Y; Katsumi, A; Hayakawa, F; Kiyoi, H; Kojima, T; Matsushita, T

INTERNATIONAL JOURNAL OF HEMATOLOGY 2024年10月

Spheroid culture to select theoretical therapeutic drugs in intravascular large B-cell lymphoma 査読有り国際誌

Takai, M; Shimada, K; Furukawa, K; Yamaga, Y; Yoshiyama, S; Kagaya, Y; Suzuki, T; Hayashi, K; Shimada, S; Karube, K; Kiyoi, H

CANCER SCIENCE 2024年10月

Newly diagnosed multiple myeloma with bleeding and coagulation abnormalities caused by a thrombin-inhibiting substance 査読有り国際誌

Ohara, F; Suzuki, A; Suzuki, N; Kanematsu, T; Okamoto, S; Tamura, S; Kiyoi, H; Matsushita, T; Katsumi, A

INTERNATIONAL JOURNAL OF HEMATOLOGY 2024年9月

Recent advances in AML with mutated NPM1 招待有り査読有り国際誌

Ishikawa, Y; Ushijima, Y; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY 2024年8月

Predictive significance of high neutrophil ratio for thrombosis in myeloproliferative neoplasms: JSH-MPN-R18 subanalysis (JUL, 10.1007/s00277-024-05898-3, 2024) 査読有り国際誌

Nagaharu, K; Ohya, E; Edahiro, Y; Hashimoto, Y; Ito, T; Gotoh, A; Nakamae, M; Kimura, F; Koike, M; Kirito, K; Wada, H; Usuki, K; Tanaka, T; Mori, T; Wakita, S; Saito, TI; Saito, AM; Shimoda, K; Kurokawa, T; Tomita, A; Kiyoi, H; Akashi, K; Matsumura, I; Takenaka, K; Komatsu, N; Ohishi, K; Tawara, I; Sugimoto, Y

ANNALS OF HEMATOLOGY 2024年8月

Predictive significance of high neutrophil ratio for thrombosis in myeloproliferative neoplasms: JSH-MPN-R18 subanalysis 査読有り国際誌

ANNALS OF HEMATOLOGY 103 巻 ( 9 ) 頁： 3535 - 3541 2024年7月

Initiating-clone analysis in patients with acute myeloid leukemia secondary to essential thrombocythemia 査読有り国際誌

Ushijima, Y; Naruse, S; Ishikawa, Y; Kawashima, N; Sanada, M; Nakashima, M; Kim, JH; Terakura, S; Kihara, R; Watamoto, K; Nishiyama, T; Kitamura, K; Matsushita, T; Kiyoi, H

SCIENTIFIC REPORTS 14 巻 ( 1 ) 頁： 15906 2024年7月

Nilotinib vs. Dasatinib in Achieving MR4.5 for de novo Chronic Myeloid Leukemia: the Randomized JALSG CML212 Study. 査読有り国際誌

Matsumura I, Ohtake S, Atsuta Y, Kurata M, Minami Y, Takahashi N, Nakaseko C, Iriyama N, Fujimaki K, Kakihana K, Ogasawara Y, Ono T, Okada M, Tauchi T, Miyamoto T, Ohnishi K, Sakaida E, Fujisawa S, Kobayashi Y, Asou N, Naoe T, Kiyoi H, Miyazaki Y

Blood advances 2024年7月

RGS1 and CREB5 are direct and common transcriptional targets of ZNF384-fusion proteins 査読有り国際誌

Yamada, C; Okada, K; Odaira, K; Tokoro, M; Iwamoto, E; Sanada, M; Noura, M; Okamoto, S; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F

CANCER MEDICINE 13 巻 ( 14 ) 頁： e7471 2024年7月

NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation 査読有り国際誌

Noura, M; Tomita, S; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F

CANCER MEDICINE 13 巻 ( 13 ) 頁： e7445 2024年7月

Human iPSC-derived CD4+Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model 査読有り国際誌

Yano, H; Koga, K; Sato, T; Shinohara, T; Iriguchi, S; Matsuda, A; Nakazono, K; Shioiri, M; Miyake, Y; Kassai, Y; Kiyoi, H; Kaneko, S

CELL STEM CELL 31 巻 ( 6 ) 頁： 795 - 802.e6 2024年6月

Phase II study in children and adults under 40 years with newly diagnosed Langerhans cell histiocytosis: protocol for an LCH-19-MSMFB clinical trial in Japan 査読有り国際誌

Ono, R; Sakamoto, K; Kudo, K; Sato, A; Kudo, K; Fujino, H; Kawahara, Y; Hashimoto, H; Doi, T; Yanagisawa, R; Kawamata, T; Miyazaki, O; Nakazawa, A; Ota, Y; Kanegane, H; Nakazawa, Y; Horibe, K; Saito, AM; Manabe, A; Usuki, K; Kiyoi, H; Morimoto, A; Tojo, A; Shioda, Y

BMJ OPEN 14 巻 ( 6 ) 頁： e084159 2024年6月

Clonal evolution process from essential thrombocythemia to acute myeloid leukemia in the original patient from whom the CALR-mutated Marimo cell line was established. 査読有り国際誌

Ushijima Y, Ishikawa Y, Nishiyama T, Kawashima N, Kanamori T, Sanada M, Kiyoi H

Nagoya journal of medical science 86 巻 ( 2 ) 頁： 326 - 332 2024年5月

A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia 査読有り国際誌

Usuki, K; Miyamoto, T; Yamauchi, T; Ando, K; Ogawa, Y; Onozawa, M; Yamauchi, T; Kiyoi, H; Yokota, A; Ikezoe, T; Katsuoka, Y; Takada, S; Aotsuka, N; Morita, Y; Ishikawa, T; Asada, N; Ota, S; Dohi, A; Morimoto, K; Imai, S; Kishimoto, U; Akashi, K; Miyazaki, Y

INTERNATIONAL JOURNAL OF HEMATOLOGY 119 巻 ( 6 ) 頁： 647 - 659 2024年3月

Novel CSF1R inhibitor, FF-10101, strongly inhibit tumor-associated macrophages and improve anti-tumor response 査読有り国際誌

Sato, T; Sugiyama, D; Kojima, Y; Hattori, S; Sone, K; Ishikawa, Y; Nishikawa, H; Kiyoi, H

CANCER SCIENCE 115 巻頁： 41 - 41 2024年3月

Utility of allogeneic stem cell transplantation for adult Ph plus ALL with complete molecular remission 査読有り国際誌

Nishiwaki, S; Sugiura, I; Fujisawa, S; Hatta, Y; Atsuta, Y; Doki, N; Kurahashi, S; Ueda, Y; Dobashi, N; Maeda, T; Matsumura, I; Tanaka, M; Kako, S; Ichinohe, T; Fukuda, T; Ohtake, S; Ishikawa, Y; Miyazaki, Y; Kiyoi, H

AMERICAN JOURNAL OF HEMATOLOGY 2024年2月

Suppression of super-enhancer-driven TAL1 expression by KLF4 in T-cell acute lymphoblastic leukemia 査読有り国際誌

Noura, M; Matsuo, H; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F

ONCOGENE 43 巻 ( 6 ) 頁： 447 - 456 2024年2月

Real-world data of MDS and CMML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11) 査読有り国際誌

Usuki, K; Ohtake, S; Honda, S; Matsuda, M; Wakita, A; Nawa, Y; Takase, K; Maeda, A; Sezaki, N; Yokoyama, H; Takada, S; Hirano, D; Tomikawa, T; Sumi, M; Yano, S; Handa, H; Ota, S; Fujita, H; Fujimaki, K; Mugitani, A; Kojima, K; Kajiguchi, T; Fujimoto, K; Asou, N; Usui, N; Ishikawa, Y; Katsumi, A; Matsumura, I; Miyazaki, Y; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY 119 巻 ( 2 ) 頁： 130 - 145 2024年2月

Epstein-Barr virus lytic gene BNRF1 promotes B-cell lymphomagenesis via IFI27 upregulation 査読有り国際誌

Sagou, K; Sato, Y; Okuno, Y; Watanabe, T; Inagaki, T; Motooka, Y; Toyokuni, S; Murata, T; Kiyoi, H; Kimura, H

PLOS PATHOGENS 20 巻 ( 2 ) 頁： e1011954 2024年2月

Real-world data of AML in Japan: results of JALSG clinical observational study-11 (JALSG-CS-11) 査読有り国際誌

INTERNATIONAL JOURNAL OF HEMATOLOGY 119 巻 ( 1 ) 頁： 24 - 38 2024年1月

Outcomes of transplant-eligible patients with myelodysplastic syndrome with excess blasts registered in an observational study: The JALSG-CS11-MDS-SCT 査読有り国際誌

Nakagawa, N; Ishiyama, K; Usuki, K; Takada, S; Tomikawa, T; Handa, H; Katsuoka, Y; Hirano, D; Sezaki, N; Sumi, M; Fujisawa, S; Taniguchi, Y; Mugitani, A; Yoshimura, T; Ohtsuka, E; Takase, K; Suehiro, Y; Ota, S; Kajiguchi, T; Maeda, T; Yamamoto, M; Ohtake, S; Katsumi, A; Kiyoi, H; Matsumura, I; Miyazaki, Y

ANNALS OF HEMATOLOGY 103 巻 ( 1 ) 頁： 307 - 320 2024年1月

Clonal hematopoiesis of a novel dic(18;20) clone following allogeneic hematopoietic stem cell transplantation 査読有り国際誌

Ito, M; Fukushima, N; Fujii, T; Numata, M; Morikawa, S; Kawamura, Y; Goto, M; Kohno, A; Imahashi, N; Yasuda, T; Sanada, M; Ishikawa, Y; Kiyoi, H; Ozeki, K

INTERNATIONAL JOURNAL OF HEMATOLOGY 119 巻 ( 1 ) 頁： 80 - 87 2024年1月

Dual CAR-T cells targeting CD19 and CD37 are effective in target antigen loss B cell tumor models. 査読有り

Imai K, Takeuchi Y, Terakura S, Okuno S, Adachi Y, Osaki M, Umemura K, Hanajiri R, Shimada K, Murata M, Kiyoi H

Molecular cancer therapeutics 2023年10月

Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts 査読有り国際誌

Takagi Erina, Terakura Seitaro, Fujigaki Hidetsugu, Okamoto Akinao, Miyao Kotaro, Sawa Masashi, Morishita Takanobu, Goto Tatsunori, Ozawa Yukiyasu, Nishida Tetsuya, Fukushima Nobuaki, Ozeki Kazutaka, Hanajiri Ryo, Saito Kuniaki, Murata Makoto, Tomita Akihiro, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 118 巻 ( 4 ) 頁： 462 - 471 2023年10月

Targeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation. 査読有り国際誌

Kurayoshi K, Takase Y, Ueno M, Ohta K, Fuse K, Ikeda S, Watanabe T, Nishida Y, Horike SI, Hosomichi K, Ishikawa Y, Tadokoro Y, Kobayashi M, Kasahara A, Jing Y, Shoulkamy MI, Meguro-Horike M, Kojima K, Kiyoi H, Sugiyama H, Nagase H, Tajima A, Hirao A

Cell death & disease 14 巻 ( 9 ) 頁： 642 2023年9月

Improved long-term net survival after allogeneic hematopoietic cell transplantation in patients with hematologic malignancies over two decades. 査読有り国際誌

Ohbiki M, Ito Y, Inamoto Y, Miyamura K, Uchida N, Fukuda T, Fujiwara H, Nishida T, Hayashi M, Tanaka M, Kawakita T, Ikegame K, Katayama Y, Ara T, Ichinohe T, Kiyoi H, Matsuo K, Atsuta Y

Transplantation and cellular therapy 2023年9月

Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice 査読有り国際誌

Sahashi Satomi, Shimada Kazuyuki, Takagi Yusuke, Aoki Tomohiro, Kunou Shunsuke, Sakamoto Akihiko, Murase Atsushi, Furukawa Katsuya, Kagaya Yusuke, Yamaga Yusuke, Takai Mika, Tokuyama Kiyonobu, Shimada Satoko, Nakamura Shigeo, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 118 巻 ( 2 ) 頁： 221 - 230 2023年8月

EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity 査読有り国際誌

Kojima Yukino, Kawashima Fumika, Yasuda Takahiko, Odaira Koya, Inagaki Yuichiro, Yamada Chiharu, Muraki Ami, Noura Mina, Okamoto Shuichi, Tamura Shogo, Iwamoto Eisuke, Sanada Masashi, Matsumura Itaru, Miyazaki Yasushi, Kojima Tetsuhito, Kiyoi Hitoshi, Tsuzuki Shinobu, Hayakawa Fumihiko

INTERNATIONAL JOURNAL OF HEMATOLOGY 118 巻 ( 1 ) 頁： 65 - 74 2023年7月

High-risk Combinations of Additional Chromosomal Abnormalities in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia: JALSG Ph plus ALL TKI-SCT Study

Nishiwaki Satoshi, Sugiura Isamu, Fujisawa Shin, Hatta Yoshihiro, Atsuta Yoshiko, Doki Noriko, Kurahashi Shingo, Ueda Yasunori, Dobashi Nobuaki, Maeda Tomoya, Taniguchi Yasuhiro, Tanaka Masatsugu, Kako Shinichi, Ichinohe Tatsuo, Fukuda Takahiro, Ohtake Shigeki, Ishikawa Yuichi, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi

HEMASPHERE 7 巻 ( 6 ) 頁： e899 2023年6月

Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosedT-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group 査読有り国際誌

Sato Atsushi, Hatta Yoshihiro, Imai Chihaya, Oshima Koichi, Okamoto Yasuhiro, Deguchi Takao, Hashii Yoshiko, Fukushima Takashi, Hori Toshinori, Kiyokawa Nobutaka, Kato Motohiro, Saito Shoji, Anami Kenichi, Sakamoto Tatsuhiro, Kosaka Yoshiyuki, Suenobu Souichi, Imamura Toshihiko, Kada Akiko, Saito Akiko M., Manabe Atsushi, Kiyoi Hitoshi, Matsumura Itaru, Koh Katsuyoshi, Watanabe Arata, Miyazaki Yasushi, Horibe Keizo

LANCET HAEMATOLOGY 10 巻 ( 6 ) 頁： 419 - 432 2023年6月

Autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia is safe but poses challenges for long-term maintenance of molecular remission: Results of the Auto-Ph17 study. 査読有り国際誌

Nishiwaki S, Sugiura I, Sato T, Kobayashi M, Osaki M, Sawa M, Adachi Y, Okabe M, Saito S, Morishita T, Kohno A, Nishiyama T, Iida H, Kurahashi S, Kuwatsuka Y, Sugiyama D, Ito S, Nishikawa H, Kiyoi H

EJHaem 4 巻 ( 2 ) 頁： 358 - 369 2023年5月

A never-ending FLT3 story 招待有り査読有り国際誌

Kiyoi, H

NAGOYA JOURNAL OF MEDICAL SCIENCE 85 巻 ( 1 ) 頁： 27 - 29 2023年2月

BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemia 査読有り国際誌

Tsuzuki Shinobu, Yasuda Takahiko, Goto Hiroaki, Maeda Naoko, Akahane Koshi, Inukai Takeshi, Yamamoto Hideyuki, Karnan Sivasundaram, Ota Akinobu, Hyodo Toshinori, Konishi Hiroyuki, Hosokawa Yoshitaka, Kiyoi Hitoshi, Hayakawa Fumihiko

HAEMATOLOGICA 108 巻 ( 2 ) 頁： 394 - 408 2023年2月

The usefulness of tranexamic acid for bleeding symptoms of chronic consumptive coagulopathy complicated by aortic disease: a single-institute, retrospective study of 14 patients 査読有り国際誌

Suzuki Naruko, Suzuki Nobuaki, Kawaguchi Yuka, Okamoto Shuichi, Kanematsu Takeshi, Katsumi Akira, Suzuki Atsuo, Tamura Shogo, Kojima Tetsuhito, Kiyoi Hitoshi, Matsushita Tadashi

THROMBOSIS JOURNAL 21 巻 ( 1 ) 頁： 10 2023年1月

[Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma]. 査読有り

Hanajiri R, Furukawa K, Nakashima M, Ushijima Y, Shimada K, Ishikawa Y, Terakura S, Murata M, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology 64 巻 ( 3 ) 頁： 167 - 174 2023年

Functional inhibition of MEF2 by C/EBP is a possible mechanism of leukemia development by CEBP-IGH fusion gene 査読有り国際誌

Odaira Koya, Yasuda Takahiko, Okada Kentaro, Shimooka Takuya, Kojima Yukino, Noura Mina, Tamura Shogo, Kurahashi Shingo, Iwamoto Eisuke, Sanada Masashi, Matsumura Itaru, Miyazaki Yasushi, Kojima Tetsuhito, Kiyoi Hitoshi, Tsuzuki Shinobu, Hayakawa Fumihiko

CANCER SCIENCE 114 巻 ( 3 ) 頁： 781 - 792 2022年11月

Methods for confirming the safety of radiation therapy in patients with left ventricular assist device: a case of extranodal NK/T-cell lymphoma, nasal type 査読有り国際誌

Oishi Hideo, Kondo Toru, Kawamura Mariko, Shimada Kazuyuki, Mutsuga Masato, Kurokawa Takashi, Kuwayama Tasuku, Hiraiwa Hiroaki, Morimoto Ryota, Okumura Takahiro, Nishida Tetsuya, Kiyoi Hitoshi, Naganawa Shinji, Usui Akihiko, Murohara Toyoaki

JOURNAL OF ARTIFICIAL ORGANS 25 巻 ( 3 ) 頁： 274 - 278 2022年9月

Prospective comparison of 5-and 7-day administration of azacitidine for myelodysplastic syndromes: a JALSG MDS212 trial 査読有り国際誌

Miyazaki Yasushi, Kiguchi Toru, Sato Shinya, Usuki Kensuke, Ishiyama Ken, Ito Yoshikazu, Suzuki Takahiro, Taguchi Jun, Chiba Shigeru, Dobashi Nobuaki, Tomita Akihiro, Harada Hironori, Handa Hiroshi, Horiike Shigeo, Maeda Tomoya, Matsuda Mitsuhiro, Ichikawa Motoshi, Hata Tomoko, Honda Sumihisa, Iyama Satoshi, Suzushima Hitoshi, Moriuchi Yukiyoshi, Kurokawa Toshiro, Yokota Kenichi, Ohtake Shigeki, Yamauchi Takahiro, Matsumura Itaru, Kiyoi Hitoshi, Naoe Tomoki

INTERNATIONAL JOURNAL OF HEMATOLOGY 116 巻 ( 2 ) 頁： 228 - 238 2022年8月

VWF-Gly2752Ser, a novel non-cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C-terminal dimer formation 査読有り国際誌

Okamoto Shuichi, Tamura Shogo, Sanda Naomi, Odaira Koya, Hayakawa Yuri, Mukaide Masato, Suzuki Atsuo, Kanematsu Takeshi, Hayakawa Fumihiko, Katsumi Akira, Kiyoi Hitoshi, Kojima Tetsuhito, Matsushita Tadashi, Suzuki Nobuaki

JOURNAL OF THROMBOSIS AND HAEMOSTASIS 20 巻 ( 8 ) 頁： 1784 - 1796 2022年8月

Real-world treatment patterns and clinical outcomes in patients with AML in Japan who were ineligible for first-line intensive chemotherapy 査読有り国際共著国際誌

Yoshida Chikashi, Kondo Takeshi, Ito Tomoki, Kizaki Masahiro, Yamamoto Kazuhiko, Miyamoto Toshihiro, Morita Yasuyoshi, Eto Tetsuya, Katsuoka Yuna, Takezako Naoki, Uoshima Nobuhiko, Imada Kazunori, Ando Jun, Komeno Takuya, Mori Akio, Ishikawa Yuichi, Satake Atsushi, Watanabe Junichi, Kawakami Yoshiko, Morita Tetsuo, Taneike Ikue, Nakayama Masahiko, Duan Yinghui, Garbayo Guijarro Belen, Delgado Alexander, Llamas Cynthia, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 116 巻 ( 1 ) 頁： 89 - 101 2022年7月

Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases 査読有り国際共著国際誌

Dai Yu-Ting, Zhang Fan, Fang Hai, Li Jian-Feng, Lu Gang, Jiang Lu, Chen Bing, Mao Dong-Dong, Liu Yuan-Fang, Wang Jin, Peng Li-Jun, Feng Chong, Chen Hai-Feng, Mu Jun-Xi, Zhang Qun-Ling, Wang Hao, Ariffin Hany, Moy Tan Ah, Wang Jing-Han, Lou Yin-Jun, Chen Su-Ning, Wang Qian, Liu Hong, Shan Zhe, Matsumura Itaru, Miyazaki Yasushi, Yasuda Takahiko, Dou Li-Ping, Yan Xiao-jing, Yan Jin-Song, Yeoh Allen Eng-Juh, Wu De-Pei, Kiyoi Hitoshi, Hayakawa Fumihiko, Jin Jie, Wang Sheng-Yue, Sun Xiao-Jian, Mi Jian-Qing, Chen Zhu, Huang Jin-Yan, Chen Sai-Juan

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119 巻 ( 15 ) 頁： e2120787119 2022年4月

Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations 査読有り国際誌

Yasuda Takahiko, Sanada Masashi, Kawazu Masahito, Kojima Shinya, Tsuzuki Shinobu, Ueno Hiroo, Iwamoto Eisuke, Iijima-Yamashita Yuka, Yamada Tomomi, Kanamori Takashi, Nishimura Rieko, Kuwatsuka Yachiyo, Takada Satoru, Tanaka Masatsugu, Ota Shuichi, Dobashi Nobuaki, Yamazaki Etsuko, Hirose Asao, Murayama Tohru, Sumi Masahiko, Sato Shinya, Tange Naoyuki, Nakamura Yukinori, Katsuoka Yuna, Sakaida Emiko, Kawamata Toyotaka, Iida Hiroatsu, Shiraishi Yuichi, Nannya Yasuhito, Ogawa Seishi, Taniwaki Masafumi, Asou Norio, Hatta Yoshihiro, Kiyoi Hitoshi, Matsumura Itaru, Horibe Keizo, Mano Hiroyuki, Naoe Tomoki, Miyazaki Yasushi, Hayakawa Fumihiko

BLOOD 139 巻 ( 12 ) 頁： 1850 - 1862 2022年3月

Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline 査読有り国際誌

Iwama Shintaro, Kobayashi Tomoko, Yasuda Yoshinori, Okuji Takayuki, Ito Masaaki, Ando Masahiko, Zhou Xin, Yamagami Ayana, Onoue Takeshi, Kawaguchi Yohei, Miyata Takashi, Sugiyama Mariko, Takagi Hiroshi, Hagiwara Daisuke, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Wakahara Keiko, Yokota Kenji, Kato Masashi, Nishio Naoki, Tanaka Chie, Miyata Kazushi, Ogura Atsushi, Ito Takanori, Sawada Tsunaki, Shimokata Tomoya, Niimi Kaoru, Ohka Fumiharu, Ishigami Masatoshi, Gotoh Momokazu, Hashimoto Naozumi, Saito Ryuta, Kiyoi Hitoshi, Kajiyama Hiroaki, Ando Yuichi, Hibi Hideharu, Sone Michihiko, Akiyama Masashi, Kodera Yasuhiro, Arima Hiroshi

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 107 巻 ( 4 ) 頁： E1620 - E1630 2022年3月

Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cells 査読有り国際誌

Adachi Yoshitaka, Sakai Toshiyasu, Terakura Seitaro, Shiina Takashi, Suzuki Shingo, Hamana Hiroshi, Kishi Hiroyuki, Sasazuki Takehiko, Arase Hisashi, Hanajiri Ryo, Goto Tatsunori, Nishida Tetsuya, Murata Makoto, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 115 巻 ( 3 ) 頁： 371 - 381 2022年3月

Decision Analysis for Unrelated Bone Marrow Transplantation or Immediate Cord Blood Transplantation for Patients with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in First Remission 査読有り国際誌

Kako Shinichi, Hayakawa Fumihiko, Miyamura Koichi, Tanaka Junji, Imai Kiyotoshi, Kanda Junya, Morishima Satoko, Uchida Naoyuki, Doki Noriko, Ikegame Kazuhiro, Ozawa Yukiyasu, Takada Satoru, Usui Noriko, Ohtake Shigeki, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi, Ichinohe Tatsuo, Fukuda Takahiro, Atsuta Yoshiko, Kanda Yoshinobu

TRANSPLANTATION AND CELLULAR THERAPY 28 巻 ( 3 ) 頁： 161.e1 - 161.e10 2022年3月

Immune effects of TKI altered immune responses after stopping TKI treatment and affected treatment-free remission rate 査読有り国際誌

Fujioka Yuki, Takahashi Naoto, Atsuta Yoshiko, Minami Yosuke, Kiyoi Hitoshi, Miyazaki Yasushi, Matsumura Itaru

CANCER SCIENCE 113 巻頁： 1712 - 1712 2022年2月

Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia 査読有り国際誌

Tsuzuki Shinobu, Yasuda Takahiko, Kawazu Masahito, Ueno Toshihide, Karnan Sivasundaram, Ota Akinobu, Sanada Masashi, Nagai Hirokazu, Tomita Akihiro, Takahashi Yoshiyuki, Miyazaki Yasushi, Matsumura Itaru, Kiyoi Hitoshi, Hosokawa Yoshitaka, Mano Hiroyuki, Hayakawa Fumihiko

CANCER SCIENCE 113 巻頁： 1236 - 1236 2022年2月

Regulatory T Cell as a Biomarker of Treatment-Free Remission in Patients with Chronic Myeloid Leukemia 査読有り国際誌

Fujioka Yuki, Sugiyama Daisuke, Matsumura Itaru, Minami Yosuke, Miura Masatomo, Atsuta Yoshiko, Ohtake Shigeki, Kiyoi Hitoshi, Miyazaki Yasushi, Nishikawa Hiroyoshi, Takahashi Naoto

CANCERS 13 巻 ( 23 ) 2021年12月

Optimal treatment for Philadelphia-negative acute lymphoblastic leukemia in first remission in the era of high-intensity chemotherapy 査読有り国際誌

Kako Shinichi, Hayakawa Fumihiko, Imai Kiyotoshi, Tanaka Junji, Mizuta Shuichi, Nishiwaki Satoshi, Kanamori Heiwa, Mukae Junichi, Ozawa Yukiyasu, Kondo Tadakazu, Fukuda Takahiro, Ichinohe Tatsuo, Ota Shuichi, Tanaka Yoshinori, Murayama Tohru, Kurahashi Shingo, Sakura Toru, Usui Noriko, Ohtake Shigeki, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi, Atsuta Yoshiko

INTERNATIONAL JOURNAL OF HEMATOLOGY 114 巻 ( 5 ) 頁： 608 - 619 2021年11月

Current progress and future perspectives of research on intravascular large B-cell lymphoma 招待有り査読有り国際誌

Shimada Kazuyuki, Kiyoi Hitoshi

CANCER SCIENCE 112 巻 ( 10 ) 頁： 3953 - 3961 2021年10月

Composite CD79A/CD40 co-stimulatory endodomain enhances CD19CAR-T cell proliferation and survival 査読有り国際誌

Julamanee Jakrawadee, Terakura Seitaro, Umemura Koji, Adachi Yoshitaka, Miyao Kotaro, Okuno Shingo, Takagi Erina, Sakai Toshiyasu, Koyama Daisuke, Goto Tatsunori, Hanajiri Ryo, Hudecek Michael, Steinberger Peter, Leitner Judith, Nishida Tetsuya, Murata Makoto, Kiyoi Hitoshi

MOLECULAR THERAPY 29 巻 ( 9 ) 頁： 2677 - 2690 2021年9月

Efficacy and safety of blinatumomab: Post hoc pooled analysis in Asian adults with relapsed/refractory B-cell precursor acute lymphoblastic leukemia 査読有り国際共著国際誌

Kobayashi Yukio, Oh Iekuni, Miyamoto Toshihiro, Lee Won-Sik, Iida Hiroatsu, Minami Hironobu, Maeda Yoshinobu, Jang Jun Ho, Yoon Sung-Soo, Yeh Su-Peng, Tran Qui, Morris Joan, Franklin Janet, Kiyoi Hitoshi

ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2021年6月

Spacer Length Modification Facilitates Discrimination between Normal and Neoplastic Cells and Provides Clinically Relevant CD37 CAR T Cells 査読有り国際誌

Okuno Shingo, Adachi Yoshitaka, Terakura Seitaro, Julamanee Jakrawadee, Sakai Toshiyasu, Umemura Koji, Miyao Kotaro, Goto Tatsunori, Murase Atsushi, Shimada Kazuyuki, Nishida Tetsuya, Murata Makoto, Kiyoi Hitoshi

JOURNAL OF IMMUNOLOGY 206 巻 ( 12 ) 頁： 2862 - 2874 2021年6月

Exosomes secreted from cancer-associated fibroblasts elicit anti-pyrimidine drug resistance through modulation of its transporter in malignant lymphoma 査読有り国際誌

Kunou Shunsuke, Shimada Kazuyuki, Takai Mika, Sakamoto Akihiko, Aoki Tomohiro, Hikita Tomoya, Kagaya Yusuke, Iwamoto Eisuke, Sanada Masashi, Shimada Satoko, Hayakawa Fumihiko, Oneyama Chitose, Kiyoi Hitoshi

ONCOGENE 40 巻 ( 23 ) 頁： 3989 - 4003 2021年6月

Phase I clinical trial of intra-bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation 査読有り国際誌

Goto Tatsunori, Murata Makoto, Nishida Tetsuya, Terakura Seitaro, Kamoshita Sonoko, Ishikawa Yuichi, Ushijima Yoko, Adachi Yoshiya, Suzuki Satoshi, Kato Katsuyoshi, Hirakawa Akihiro, Nishiwaki Satoshi, Nishio Nobuhiro, Takahashi Yoshiyuki, Kodera Yoshihisa, Matsushita Tadashi, Kiyoi Hitoshi

STEM CELLS TRANSLATIONAL MEDICINE 10 巻 ( 4 ) 頁： 542 - 553 2021年4月

Combination of clofarabine, etoposide, and cyclophosphamide in adult relapsed/refractory acute lymphoblastic leukemia: a phase 1/2 dose-escalation study by the Japan Adult Leukemia Study Group 査読有り国際誌

Saito Takeshi, Hatta Yoshihiro, Hayakawa Fumihiko, Takahashi Tsutomu, Hagihara Maki, Iida Hiroatsu, Minauchi Koichiro, Yamazaki Etsuko, Sugiura Isamu, Murayama Tohru, Sakura Toru, Mori Naoki, Imai Kiyotoshi, Yahagi Yuichi, Atsuta Yoshiko, Saito Akiko Moriya, Hirakawa Akihiro, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi

INTERNATIONAL JOURNAL OF HEMATOLOGY 113 巻 ( 3 ) 頁： 395 - 403 2021年3月

Machine learning-aided risk stratification in Philadelphia chromosome-positive acute lymphoblastic leukemia

Nishiwaki Satoshi, Sugiura Isamu, Koyama Daisuke, Ozawa Yukiyasu, Osaki Masahide, Ishikawa Yuichi, Kiyoi Hitoshi

BIOMARKER RESEARCH 9 巻 ( 1 ) 頁： 13 2021年2月

Impact of variation in reagent combinations for one-stage clotting assay on assay discrepancy in nonsevere haemophilia A 査読有り国際誌

Suzuki Atsuo, Suzuki Nobuaki, Kanematsu Takeshi, Okamoto Shuichi, Tamura Shogo, Kikuchi Ryosuke, Katsumi Akira, Kiyoi Hitoshi, Kojima Tetsuhito, Matsushita Tadashi

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY 43 巻 ( 1 ) 頁： 131 - 138 2021年2月

Myh9 R702C is associated with erythroid abnormality with splenomegaly in mice 査読有り国際誌

Kanematsu, T; Suzuki, N; Tamura, S; Suzuki, A; Ishikawa, Y; Katsumi, A; Kiyoi, H; Saito, H; Kunishima, S; Kojima, T; Matsushita, T

NAGOYA JOURNAL OF MEDICAL SCIENCE 83 巻 ( 1 ) 頁： 75 - 86 2021年2月

Exosomes derived from cancer associated fibroblasts induce a resistance to histone deacetylase inhibitors in lymphoma 査読有り国際誌

Kagaya Yusuke, Shimada Kazuyuki, Kunou Shunsuke, Hikita Tomoya, Sakamoto Akihiko, Hayakawa Fumihiko, Oneyama Chitose, Kiyoi Hitoshi

CANCER SCIENCE 112 巻頁： 370 - 370 2021年2月

Research on FLT3 mutations and targeted therapeutics 招待有り国際誌

Naoe Tomoki, Kiyoi Hitoshi, Yokota Shohei

CANCER SCIENCE 112 巻頁： 1016 - 1016 2021年2月

A case of reexpansion pulmonary edema and acute pulmonary thromboembolism associated with diffuse large B-cell lymphoma treated with venovenous extracorporeal membrane oxygenation. 査読有り国際誌

Kazama S, Hiraiwa H, Kimura Y, Ozaki R, Shibata N, Arao Y, Oishi H, Kato H, Kuwayama T, Yamaguchi S, Kondo T, Furusawa K, Morimoto R, Okumura T, Bando YK, Sato T, Shimada K, Kiyoi H, Nakamura G, Yasuda Y, Kasugai D, Ogawa H, Higashi M, Yamamoto T, Jingushi N, Ozaki M, Numaguchi A, Goto Y, Matsuda N, Murohara T

Journal of cardiology cases 23 巻 ( 1 ) 頁： 53 - 56 2021年1月

Bursitis, Bacteremia, and Disseminated Infection of Mycobacteroides (Mycobacterium) abscessus subsp. massiliense 査読有り国際誌

Oka Keisuke, Morioka Hiroshi, Eguchi Motoki, Sato Yoshitaka, Tetsuka Nobuyuki, Iguchi Mitsutaka, Kanematsu Takeshi, Fukano Hanako, Hoshino Yoshihiko, Kiyoi Hitoshi, Yagi Tetsuya

INTERNAL MEDICINE 60 巻 ( 18 ) 頁： 3041 - 3045 2021年

Predictors of early death, serious hemorrhage, and differentiation syndrome in Japanese patients with acute promyelocytic leukemia 査読有り国際誌

Minamiguchi Hitoshi, Fujita Hiroyuki, Atsuta Yoshiko, Asou Norio, Sakura Toru, Ueda Yasunori, Sawa Masashi, Dobashi Nobuaki, Taniguchi Yasuhiro, Suzuki Rikio, Uchino Yoshihito, Tomita Akihiro, Tamaki Shigehisa, Hagihara Maki, Fujimaki Katsumichi, Yanada Masamitsu, Maeda Yoshinobu, Iwanaga Masako, Usui Noriko, Kobayashi Yukio, Ohtake Shigeki, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi, Naoe Tomoki, Takeshita Akihiro

ANNALS OF HEMATOLOGY 99 巻 ( 12 ) 頁： 2787 - 2800 2020年12月

Multi-Lineage BCR-ABL Expression in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Is Associated With Improved Prognosis but No Specific Molecular Features 査読有り国際誌

Nishiwaki Satoshi, Kim Jeong Hui, Ito Masafumi, Maeda Matsuyoshi, Okuno Yusuke, Koyama Daisuke, Ozawa Yukiyasu, Gunji Masaharu, Osaki Masahide, Kitamura Kunio, Ushijima Yoko, Ishikawa Yuichi, Miyamura Koichi, Sugiura Isamu, Kiyoi Hitoshi

FRONTIERS IN ONCOLOGY 10 巻頁： 586567 2020年10月

Phase I study of duvelisib in Japanese patients with relapsed or refractory lymphoma 査読有り国際誌

Izutsu Koji, Kato Koji, Kiyoi Hitoshi, Yamamoto Go, Shimada Kazuyuki, Akashi Koichi

INTERNATIONAL JOURNAL OF HEMATOLOGY 112 巻 ( 4 ) 頁： 504 - 509 2020年10月

Artificial T Cell Adaptor Molecule-Transduced TCR-T Cells Demonstrated Improved Proliferation Only When Transduced in a Higher Intensity 査読有り国際誌

Sakai Toshiyasu, Terakura Seitaro, Miyao Kotaro, Okuno Shingo, Adachi Yoshitaka, Umemura Koji, Julamanee Jakrawadee, Watanabe Keisuke, Hamana Hiroshi, Kishi Hiroyuki, Leitner Judith, Steinberger Peter, Nishida Tetsuya, Murata Makoto, Kiyoi Hitoshi

MOLECULAR THERAPY-ONCOLYTICS 18 巻頁： 613 - 622 2020年9月

Real-world management of infection during chemotherapy for acute leukemia in Japan: from the results of a nationwide questionnaire-based survey by the Japan Adult Leukemia Study Group 査読有り国際誌

Kimura Shun-ichi, Fujita Hanako, Handa Hiroshi, Hiramoto Nobuhiro, Hosono Naoko, Minamiguchi Hitoshi, Takahashi Tsutomu, Kato Hideaki, Ono Takaaki, Kanda Yoshinobu, Kiyoi Hitoshi, Matsumura Itaru, Miyazaki Yasushi

INTERNATIONAL JOURNAL OF HEMATOLOGY 112 巻 ( 3 ) 頁： 409 - 417 2020年9月

Clinical utility of target capture-based panel sequencing in hematological malignancies: A multicenter feasibility study 査読有り国際誌

Yasuda Takahiko, Sanada Masashi, Nishijima Dai, Kanamori Takashi, Iijima Yuka, Hattori Hiroyoshi, Saito Akiko, Miyoshi Hiroaki, Ishikawa Yuichi, Asou Norio, Usuki Kensuke, Hirabayashi Shinsuke, Kato Motohiro, Ri Masaki, Handa Hiroshi, Ishida Tadao, Shibayama Hirohiko, Abe Masahiro, Iriyama Chisako, Karube Kennosuke, Nishikori Momoko, Ohshima Koichi, Kataoka Keisuke, Yoshida Kenichi, Shiraishi Yuichi, Goto Hiroaki, Adachi Souichi, Kobayashi Ryoji, Kiyoi Hitoshi, Miyazaki Yasushi, Ogawa Seishi, Kurahashi Hiroki, Yokoyama Hisayuki, Manabe Atsushi, Iida Shinsuke, Tomita Akihiro, Horibe Keizo

CANCER SCIENCE 111 巻 ( 9 ) 頁： 3367 - 3378 2020年9月

Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia (vol 111, pg 1314, 2020) 査読有り国際共著国際誌

Kiyoi Hitoshi, Morris Joan D., Oh Iekuni, Maeda Yoshinobu, Minami Hironobu, Miyamoto Toshihiro, Sakura Toru, Iida Hiroatsu, Tuglus Catherine A., Chen Yuqi, Dos Santos Cedric, Kalabus James, Anderson Abraham, Hata Tomoko, Nakashima Yasuhiro, Kobayashi Yukio

CANCER SCIENCE 111 巻 ( 8 ) 頁： 3082 - 3082 2020年8月

Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells 査読有り国際誌

Tange Naoyuki, Hayakawa Fumihiko, Yasuda Takahiko, Odaira Koya, Yamamoto Hideyuki, Hirano Daiki, Sakai Toshiyasu, Terakura Seitaro, Tsuzuki Shinobu, Kiyoi Hitoshi

BIOMEDICINE & PHARMACOTHERAPY 128 巻頁： 110330 2020年8月

Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia. 査読有り国際誌

Tsuzuki S, Yasuda T, Kojima S, Kawazu M, Akahane K, Inukai T, Imaizumi M, Morishita T, Miyamura K, Ueno T, Karnan S, Ota A, Hyodo T, Konishi H, Sanada M, Nagai H, Horibe K, Tomita A, Suzuki K, Muramatsu H, Takahashi Y, Miyazaki Y, Matsumura I, Kiyoi H, Hosokawa Y, Mano H, Hayakawa F

Blood cancer discovery 1 巻 ( 1 ) 頁： 82 - 95 2020年7月

Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia 査読有り国際誌

Tsuzuki Shinobu, Yasuda Takahiko, Kojima Shinya, Kawazu Masahito, Akahane Koshi, Inukai Takeshi, Imaizumi Masue, Morishita Takanobu, Miyamura Koichi, Ueno Toshihide, Karnan Sivasundaram, Ota Akinobu, Hyodo Toshinori, Konishi Hiroyuki, Sanada Masashi, Nagai Hirokazu, Horibe Keizo, Tomita Akihiro, Suzuki Kyogo, Muramatsu Hideki, Takahashi Yoshiyuki, Miyazaki Yasushi, Matsumura Itaru, Kiyoi Hitoshi, Hosokawa Yoshitaka, Mano Hiroyuki, Hayakawa Fumihiko

BLOOD CANCER DISCOVERY 1 巻 ( 1 ) 頁： 82 - 95 2020年7月

Real world data of liver injury induced by immune checkpoint inhibitors in Japanese patients with advanced malignancies 査読有り国際誌

Mizuno Kazuyuki, Ito Takanori, Ishigami Masatoshi, Ishizu Yoji, Kuzuya Teiji, Honda Takashi, Kawashima Hiroki, Inukai Yosuke, Toyoda Hidenori, Yokota Kenji, Hase Tetsunari, Maeda Osamu, Kiyoi Hitoshi, Nagino Masato, Hibi Hideharu, Kodera Yasuhiro, Fujimoto Yasushi, Sone Michihiko, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Fujishiro Mitsuhiro

JOURNAL OF GASTROENTEROLOGY 55 巻 ( 6 ) 頁： 653 - 661 2020年6月

Impact of CD56 Continuously Recognizable as Prognostic Value of Acute Promyelocytic Leukemia: Results of Multivariate Analyses in the Japan Adult Leukemia Study Group (JALSG)-APL204 Study and a Review of the Literature 査読有り国際誌

Takeshita Akihiro, Asou Norio, Atsuta Yoshiko, Furumaki Hiroaki, Sakura Toru, Ueda Yasunori, Sawa Masashi, Dobashi Nobuaki, Taniguchi Yasuhiro, Suzuki Rikio, Nakagawa Masaru, Tamaki Shigehisa, Hagihara Maki, Fujimaki Katsumichi, Minamiguchi Hitoshi, Fujita Hiroyuki, Yanada Masamitsu, Maeda Yoshinobu, Usui Noriko, Kobayashi Yukio, Kiyoi Hitoshi, Ohtake Shigeki, Matsumura Itaru, Naoe Tomoki, Miyazaki Yasushi

CANCERS 12 巻 ( 6 ) 2020年6月

JSH Practical Guidelines for Hematological Malignancies, 2018: I. Leukemia-1. Acute myeloid leukemia (AML) 招待有り査読有り国際誌

Kiyoi Hitoshi, Yamaguchi Hiroki, Maeda Yoshinobu, Yamauchi Takahiro

INTERNATIONAL JOURNAL OF HEMATOLOGY 111 巻 ( 5 ) 頁： 595 - 613 2020年5月

Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial 査読有り国際誌

Shimada Kazuyuki, Yamaguchi Motoko, Atsuta Yoshiko, Matsue Kosei, Sato Keijiro, Kusumoto Shigeru, Nagai Hirokazu, Takizawa Jun, Fukuhara Noriko, Nagafuji Koji, Miyazaki Kana, Ohtsuka Eiichi, Okamoto Masataka, Sugita Yasumasa, Uchida Toshiki, Kayukawa Satoshi, Wake Atsushi, Ennishi Daisuke, Kondo Yukio, Izumi Tohru, Kin Yoshihiro, Tsukasaki Kunihiro, Hashimoto Daigo, Yuge Masaaki, Yanagisawa Atsumi, Kuwatsuka Yachiyo, Shimada Satoko, Masaki Yasufumi, Niitsu Nozomi, Kiyoi Hitoshi, Suzuki Ritsuro, Tokunaga Takashi, Nakamura Shigeo, Kinoshita Tomohiro

LANCET ONCOLOGY 21 巻 ( 4 ) 頁： 593 - 602 2020年4月

Phase 1b/2 study of blinatumomab in Japanese adults with relapsed/refractory acute lymphoblastic leukemia 査読有り国際共著国際誌

Kiyoi Hitoshi, Morris Joan D., Oh Lekuni, Maeda Yoshinobu, Minami Hironobu, Miyamoto Toshihiro, Sakura Toru, Iida Hiroatsu, Tuglus Catherine A., Chen Yuqi, Dos Santos Cedric, Kalabus James, Anderson Abraham, Hata Tomoko, Nakashima Yasuhiro, Kobayashi Yukio

CANCER SCIENCE 111 巻 ( 4 ) 頁： 1314 - 1323 2020年4月

Higher FVIII:C measured by chromogenic substrate assay than by one-stage assay is associated with silent hemophilic arthropathy 査読有り国際誌

Ogawa Mika, Suzuki Nobuaki, Takahashi Nobunori, Tamura Shogo, Suzuki Atsuo, Suzuki Sachiko, Hattori Yuua, Kakihara Misaki, Kanematsu Takeshi, Kojima Toshihisa, Katsumi Akira, Hayakawa Fumihiko, Kojima Tetsuhito, Ishiguro Naoki, Kiyoi Hitoshi, Matsushita Tadashi

THROMBOSIS RESEARCH 188 巻頁： 103 - 105 2020年4月

Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study 査読有り国際誌

Okada Norio, Iwama Shintaro, Okuji Takayuki, Kobayashi Tomoko, Yasuda Yoshinori, Wada Eri, Onoue Takeshi, Goto Motomitsu, Sugiyama Mariko, Tsunekawa Taku, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Suga Hidetaka, Banno Ryoichi, Hase Tetsunari, Morise Masahiro, Kanda Mitsuro, Yokota Kenji, Hashimoto Naozumi, Ando Masahiko, Fujimoto Yasushi, Nagino Masato, Kodera Yasuhiro, Fujishiro Mitsuhiro, Hibi Hideharu, Sone Michihiko, Kiyoi Hitoshi, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

BRITISH JOURNAL OF CANCER 122 巻 ( 6 ) 頁： 771 - 777 2020年3月

悪性リンパ腫診療の進歩とピットフォール招待有り

島田和之、清井仁

日本内科学会雑誌 109 巻 ( 3 ) 頁： 574 - 578 2020年3月

FLT3 mutations in acute myeloid leukemia: Therapeutic paradigm beyond inhibitor development 招待有り査読有り国際誌

Kiyoi, H; Kawashima, N; Ishikawa, Y

CANCER SCIENCE 111 巻 ( 2 ) 頁： 312 - 322 2020年2月

Prospective evaluation of prognostic impact of KIT mutations on acute myeloid leukemia with RUNX1-RUNX1T1 and CBFB-MYH11 査読有り国際誌

Ishikawa Yuichi, Kawashima Naomi, Atsuta Yoshiko, Sugiura Isamu, Sawa Masashi, Dobashi Nobuaki, Yokoyama Hisayuki, Doki Noriko, Tomita Akihiro, Kiguchi Toru, Koh Shiro, Kanamori Heiwa, Iriyama Noriyoshi, Kohno Akio, Moriuchi Yukiyoshi, Asada Noboru, Hirano Daiki, Togitani Kazuto, Sakura Toru, Hagihara Maki, Tomikawa Tatsuki, Yokoyama Yasuhisa, Asou Norio, Ohtake Shigeki, Matsumura Itaru, Miyazaki Yasushi, Naoe Tomoki, Kiyoi Hitoshi

BLOOD ADVANCES 4 巻 ( 1 ) 頁： 66 - 75 2020年1月

Donor single nucleotide polymorphism in ACAT1 affects the incidence of graft-versus-host disease after bone marrow transplantation 査読有り国際誌

Kamoshita Sonoko, Murata Makoto, Koyama Daisuke, Julamanee Jakrawadee, Okuno Shingo, Takagi Erina, Miyao Kotaro, Goto Tatsunori, Ozawa Yukiyasu, Miyamura Koichi, Terakura Seitaro, Nishida Tetsuya, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 111 巻 ( 1 ) 頁： 112 - 119 2020年1月

Successful Introduction of Peritoneal Dialysis in an End-stage Renal Failure Patient with Idiopathic Aplastic Anemia 査読有り国際誌

Suzuki Yasuhiro, Mizuno Masashi, Sakata Fumiko, Kojima Hiroshi, Sato Yuka, Kishimoto Mayuko, Suzuki Nobuaki, Kinashi Hiroshi, Saito Shoji, Katsuno Takayuki, Kosugi Tomoki, Maruyama Shoichi, Murata Makoto, Kiyoi Hitoshi, Ito Yasuhiko

INTERNAL MEDICINE 59 巻 ( 5 ) 頁： 683 - 687 2020年

Allogeneic Hematopoietic Stem Cell Transplantation for Post-essential Thrombocythemia and Post-polycythemia Vera Myelofibrosis 査読有り国際誌

Murata, M; Suzuki, R; Nishida, T; Shirane, S; Shimazu, Y; Minami, Y; Mori, T; Doki, N; Kanda, Y; Uchida, N; Tanaka, M; Ishikawa, J; Togitani, K; Fukuda, T; Ichinohe, T; Atsuta, Y; Nagamura-Inoue, T; Kiyoi, H

INTERNAL MEDICINE 59 巻 ( 16 ) 頁： 1947 - 1956 2020年

Successful Perioperative Combination of High-Dose FVIII Therapy Followed by Emicizumab in a Patient with Hemophilia A with Inhibitors.

Okamoto S, Suzuki N, Suzuki A, Suzuki S, Tamura S, Suzuki M, Takahashi N, Kojima T, Kanematsu T, Kojima T, Kiyoi H, Ishiguro N, Matsushita T

TH open : companion journal to thrombosis and haemostasis 3 巻 ( 4 ) 頁： e364-e366 2019年10月

ZNF384-fusion proteins have high affinity for the transcriptional coactivator EP300 and aberrant transcriptional activities 査読有り国際誌

Yamamoto Hideyuki, Hayakawa Fumihiko, Yasuda Takahiko, Odaira Koya, Minamikawa Yuka, Tange Naoyuki, Hirano Daiki, Kojima Yuki, Morishita Takanobu, Tsuzuki Shinobu, Naoe Tomoki, Kiyoi Hitoshi

FEBS LETTERS 593 巻 ( 16 ) 頁： 2151 - 2161 2019年8月

Exome analysis of treatment-related AML after APL suggests secondary evolution 査読有り国際共著国際誌

Wang Tianjiao, Jacoby Meagan A., Duncavage Eric J., Miller Christopher A., Heath Sharon, Rahme Ramy, Fenaux Pierre, Ades Lionel, Renneville Aline, Cassinat Bruno, Takeshita Akihiro, Asou Norio, Miyazaki Yasushi, Kiyoi Hitoshi, Ravandi Farhad, Westervelt Peter, Wartman Lukas D., Welch John S.

BRITISH JOURNAL OF HAEMATOLOGY 185 巻 ( 5 ) 頁： 984 - 987 2019年6月

Efficacy and safety of tyrosine kinase inhibitors for newly diagnosed chronic-phase chronic myeloid leukemia over a 5-year period: results from the Japanese registry obtained by the New TARGET system 招待有り査読有り国際誌

Kizaki Masahiro, Takahashi Naoto, Iriyama Noriyoshi, Okamoto Shinichiro, Ono Takaaki, Usui Noriko, Inokuchi Koiti, Nakaseko Chiaki, Kurokawa Mineo, Sumi Masahiko, Nakamura Fumihiko, Kawaguchi Tatsuya, Suzuki Ritsuro, Yamamoto Kazuhito, Ohnishi Kazunori, Matsumura Itaru, Naoe Tomoki, Kizaki M., Mori S., Nemoto T., Sagawa M., Tabayashi T., Tokuhira M., Tomikawa T., Watanabe R., Hatta Y., Inoue Y., Iriyama N., Kobayashi S., Kobayashi Y., Kurita D., Karigane D., Kasahara H., Koda Y., Miyakawa Y., Murakami K., Okamoto S., Watanuki S., Ono T., Nagata Y., Takeshita A., Takahashi N., Kameoka Y., Yoshioka T., Takahashi S., Usui N., Dan K., Inokuchi K., Nakamura K., Abe D., Nakaseko C., Ohwada C., Sakaida E., Shimizu N., Takeuchi M., Arai S., Kogure Y., Koya A., Masamoto Y., Masuda A., Nakazaki K., Toyama K., Hiroshima Y., Ichikawa N., Kirihara T., Kobayashi H., Shimizu I., Sumi M., Ueki T., Hagiwara S., Hirai R., Miwa T., Nakamura F., Nakamura M., Takeshita M., Tanimura A., Hayakawa F., Ishikawa Y., Kiyoi H., Murata M., Tomita A., Kurokawa T., Sugimori C., Arai A., Miura O., Yamamoto M., Imai K., Kobayashi N., Minauchi K., Obara M., Ota S., Ikezoe T., Mori M., Sakai M., Taniguchi A., Togitani K., Hayakawa H., Kajiguchi T., Kamoshita S., Otsuka E., Nishida A., Saburi M., Saburi Y., Iida H., Kato C., Kojima Y., Ohashi H., Miyata Y., Sugimoto K., Yamamoto H., Yokozawa T., Kamae T., Kuyama J., Mitsui H., Morikawa Y., Uchida Y., Ashida T., Hirase C., Kawanishi K., Matsumura I., Miyatake J., Morita Y., Sano T., Shimada T., Tanaka H., Taniguchi Y., Tatsumi Y., Yamaguchi K., Ishida F., Momose K., Nakazawa H., Nishina S., Sakai H., Sekiguchi N., Ito Y., Ohyashiki K., Tauchi T., Hata T., Imaizumi Y., Imanishi D., Itonaga H., Makiyama J., Sawayama Y., Taguchi J., Taguchi M., Taniguchi H., Eguchi G., Matsuda M., Yamairi N., Fukushima N., Ozeki K., Kohno A., Sakura T., Takada S., Kobayashi T., Sakamaki H., Asou N., Kawaguchi T., Kiguchi T., Masunari T., Sezaki N., Iino M., Morinaga K., Ikeda K., Ogawa K., Noji H., Iwasaki H., Takenaka K., Miyamoto T., Handa H., Murakami H., Tsukamoto N., Eto T., Henzan H., Kamitsuji Y., Uoshima N., Hagihara M., Takahashi H., Emi N., Okamoto M., Kawakami K., Waki M., Fukuhara N., Harigae H., Murayama T., Mizuno I., Okumura H., Tsutsumi Y., Usuki K., Fujisaki T., Maeda Y., Suehiro Y., Suzushima H., Yamamoto K., Kanakura Y., Nagasaki K., Muto H., Fujisawa S., Mugitani A., Yamasaki S., Adachi Y., Kamimura T., Takamatsu Y., Ryu T., Chiba S., Ohishi K., Suzuki K., Ogawa D., Mihara H., Fujita H., Kubo K., Yokota A., Yoshida C., Nakachi S., Myojyo T., Kitabayashi A., Suzumiya J., Hino M., Wakita A., Shibata T., Takahashi T., Takamatsu H., Fujimaki K., Tajika K., Mita M., Terui Y., Ito M., Yamane T., Yamamoto K., Yamauchi T., Kohara Y., Takebayashi C., Inagaki A., Tsuji M., Shinzaki H., Moriuchi Y., Ishikawa M., Miyazaki K., Shima E., Kinugawa N.

INTERNATIONAL JOURNAL OF HEMATOLOGY 109 巻 ( 4 ) 頁： 426 - 439 2019年4月

Chromosomal translocation-mediated evasion from miRNA induces strong MEF2D fusion protein expression, causing inhibition of PAX5 transcriptional activity 査読有り国際誌

Hirano Daiki, Hayakawa Fumihiko, Yasuda Takahiko, Tange Naoyuki, Yamamoto Hideyuki, Kojima Yuki, Morishita Takanobu, Imoto Naoto, Tsuzuki Shinobu, Mano Hiroyuki, Naoe Tomoki, Kiyoi Hitoshi

ONCOGENE 38 巻 ( 13 ) 頁： 2263 - 2274 2019年3月

Defective Epstein-Barr virus in chronic active infection and haematological malignancy 査読有り国際誌

Okuno Yusuke, Murata Takayuki, Sato Yoshitaka, Muramatsu Hideki, Ito Yoshinori, Watanabe Takahiro, Okuno Tatsuya, Murakami Norihiro, Yoshida Kenichi, Sawada Akihisa, Inoue Masami, Kawa Keisei, Seto Masao, Ohshima Koichi, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Narita Yohei, Yoshida Masahiro, Goshima Fumi, Kawada Jun-Ichi, Nishida Tetsuya, Kiyoi Hitoshi, Kato Seiichi, Nakamura Shigeo, Morishima Satoko, Yoshikawa Tetsushi, Fujiwara Shigeyoshi, Shimizu Norio, Isobe Yasushi, Noguchi Masaaki, Kikuta Atsushi, Iwatsuki Keiji, Takahashi Yoshiyuki, Kojima Seiji, Ogawa Seishi, Kimura Hiroshi

NATURE MICROBIOLOGY 4 巻 ( 3 ) 頁： 404 - 413 2019年3月

Quantitative Assessment of T Cell Clonotypes in Human Acute Graft-versus-Host Disease Tissues 査読有り国際誌

Koyama Daisuke, Murata Makoto, Hanajiri Ryo, Akashi Tomohiro, Okuno Shingo, Kamoshita Sonoko, Julamanee Jakrawadee, Takagi Erina, Miyao Kotaro, Sakemura Reona, Goto Tatsunori, Terakura Seitaro, Nishida Tetsuya, Kiyoi Hitoshi

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 25 巻 ( 3 ) 頁： 417 - 423 2019年3月

Publisher Correction: Defective Epstein-Barr virus in chronic active infection and haematological malignancy. 査読有り国際誌

Okuno Y, Murata T, Sato Y, Muramatsu H, Ito Y, Watanabe T, Okuno T, Murakami N, Yoshida K, Sawada A, Inoue M, Kawa K, Seto M, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Narita Y, Yoshida M, Goshima F, Kawada JI, Nishida T, Kiyoi H, Kato S, Nakamura S, Morishima S, Yoshikawa T, Fujiwara S, Shimizu N, Isobe Y, Noguchi M, Kikuta A, Iwatsuki K, Takahashi Y, Kojima S, Ogawa S, Kimura H

Nature microbiology 4 巻 ( 3 ) 頁： 544 2019年3月

Tamibarotene maintenance improved relapse-free survival of acute promyelocytic leukemia: a final result of prospective, randomized, JALSG-APL204 study 査読有り国際誌

Takeshita Akihiro, Asou Norio, Atsuta Yoshiko, Sakura Toru, Ueda Yasunori, Sawa Masashi, Dobashi Nobuaki, Taniguchi Yasuhiro, Suzuki Rikio, Nakagawa Masaru, Tamaki Shigehisa, Hagihara Maki, Fujimaki Katsumichi, Furumaki Hiroaki, Obata Yukako, Fujita Hiroyuki, Yanada Masamitsu, Maeda Yoshinobu, Usui Noriko, Kobayashi Yukio, Kiyoi Hitoshi, Ohtake Shigeki, Matsumura Itaru, Naoe Tomoki, Miyazaki Yasushi

LEUKEMIA 33 巻 ( 2 ) 頁： 358 - 370 2019年2月

Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study 査読有り国際誌

Kawashima Naomi, Akashi Akimi, Nagata Yasunobu, Kihara Rika, Ishikawa Yuichi, Asou Norio, Ohtake Shigeki, Miyawaki Shuichi, Sakura Toru, Ozawa Yukiyasu, Usui Noriko, Kanamori Heiwa, Ito Yoshikazu, Imai Kiyotoshi, Suehiro Youko, Kitamura Kunio, Sakaida Emiko, Takeshita Akihiro, Suzushima Hitoshi, Naoe Tomoki, Matsumura Itaru, Miyazaki Yasushi, Ogawa Seishi, Kiyoi Hitoshi

ANNALS OF HEMATOLOGY 98 巻 ( 1 ) 頁： 83 - 91 2019年1月

[Successful treatment of pre-engraftment disseminated fusariosis with high-dose liposomal amphotericin B in a cord blood transplant recipient]. 査読有り

Harada Y, Murata M, Matsumoto A, Kato D, Yagi T, Yaguchi T, Yoshikawa T, Takeichi T, Akiyama M, Yamaguchi Y, Koyama D, Terakura S, Nishida T, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology 60 巻 ( 12 ) 頁： 1641 - 1646 2019年

[Acute myeloid leukemia: AML]. 招待有り

Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology 60 巻 ( 3 ) 頁： 224 - 225 2019年

Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases. 査読有り

Proceedings of the National Academy of Sciences of the United States of America 2018年11月

Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells. 査読有り

Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H

Cancer science 2018年11月

Prognostic Analysis According to the 2017 ELN Risk Stratification by Genetics in Adult Acute Myeloid Leukemia Patients Treated in The Japan Adult Leukemia Study Group (JALSG) AML201 study 査読有り

Harada Yasuhiko, Nagata Yasunobu, Kihara Rika, Ishikawa Yuichi, Asou Norio, Ohtake Shigeki, Miyawaki Shuichi, Sakura Toru, Ozawa Yukiyasu, Usui Noriko, Kanamori Heiwa, Ito Yoshikazu, Imai Kiyotoshi, Suehiro Youko, Kobayashi Shinichi, Kitamura Kunio, Sakaida Emiko, Onizuka Makoto, Takeshita Akihiro, Ishida Fumihiro, Suzushima Hitoshi, Ishizawa Kenichi, Naoe Tomoki, Matsumura Itaru, Miyazaki Yasushi, Ogawa Seishi, Kiyoi Hitoshi

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA 18 巻頁： S196-S196 2018年9月

Impact of hospital length of stay on the risk of readmission and overall survival after allogeneic stem cell transplantation 査読有り国際誌

Seto Aika, Atsuta Yoshiko, Kawashima Naomi, Ozawa Yukiyasu, Miyamura Koichi, Kiyoi Hitoshi

INTERNATIONAL JOURNAL OF HEMATOLOGY 108 巻 ( 3 ) 頁： 290 - 297 2018年9月

Final analysis of the JALSG Ph+ALL202 study: tyrosine kinase inhibitor-combined chemotherapy for Ph plus ALL 査読有り国際誌

Hatta Yoshihiro, Mizuta Shuichi, Matsuo Keitaro, Ohtake Shigeki, Iwanaga Masako, Sugiura Isamu, Doki Noriko, Kanamori Heiwa, Ueda Yasunori, Yoshida Chikamasa, Dobashi Nobuaki, Maeda Tomoya, Yujiri Toshiaki, Monma Fumihiko, Ito Yoshikazu, Hayakawa Fumihiko, Takeuchi Jin, Kiyoi Hitoshi, Miyazaki Yasushi, Naoe Tomoki

ANNALS OF HEMATOLOGY 97 巻 ( 9 ) 頁： 1535 - 1545 2018年9月

Biology and management of primary effusion lymphoma. 査読有り

Shimada K, Hayakawa F, Kiyoi H

Blood 2018年8月

Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response 査読有り国際誌

Ueda Norihiro, Uemura Yasushi, Zhang Rong, Kitayama Shuichi, Iriguchi Shoichi, Kawai Yohei, Yasui Yutaka, Tatsumi Minako, Ueda Tatsuki, Liu Tian-Yi, Mizoro Yasutaka, Okada Chihiro, Watanabe Akira, Nakanishi Mahito, Senju Satoru, Nishimura Yasuharu, Kuzushima Kiyotaka, Kiyoi Hitoshi, Naoe Tomoki, Kaneko Shin

STEM CELL REPORTS 10 巻 ( 6 ) 頁： 1935 - 1946 2018年6月

Infectious complications in adults undergoing intensive chemotherapy for acute myeloid leukemia in 2001-2005 using the Japan Adult Leukemia Study Group AML201 protocols.

Kato H, Fujita H, Akiyama N, Kimura SI, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Minamiguchi H, Miyatake J, Handa H, Kanda Y, Yoshida M, Miyawaki S, Ohtake S, Naoe T, Kiyoi H, Matsumura I, Miyazaki Y, Japan Adult Leukemia Study Group.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2018年6月

Introduction of Genetically Modified CD3 zeta Improves Proliferation and Persistence of Antigen-Specific CTLs 査読有り国際誌

Miyao Kotaro, Terakura Seitaro, Okuno Shingo, Julamanee Jakrawadee, Watanabe Keisuke, Hamana Hiroshi, Kishi Hiroyuki, Sakemura Reona, Koyama Daisuke, Goto Tatsunori, Nishida Tetsuya, Murata Makoto, Kiyoi Hitoshi

CANCER IMMUNOLOGY RESEARCH 6 巻 ( 6 ) 頁： 733 - 744 2018年6月

Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia. 査読有り

Tanaka Y, Kawazu M, Yasuda T, Tamura M, Hayakawa F, Kojima S, Ueno T, Kiyoi H, Naoe T, Mano H

Haematologica 2018年5月

Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol 査読有り国際誌

Goto Tatsunori, Murata Makoto, Terakura Seitaro, Nishida Tetsuya, Adachi Yoshiya, Ushijima Yoko, Shimada Kazuyuki, Ishikawa Yuichi, Hayakawa Fumihiko, Nishio Nobuhiro, Nishiwaki Satoshi, Hirakawa Akihiro, Kato Katsuyoshi, Takahashi Yoshiyuki, Kiyoi Hitoshi

MEDICINE 97 巻 ( 17 ) 頁： e0449 2018年4月

Mutation analysis of therapy-related myeloid neoplasms 査読有り国際誌

Nishiyama Takahiro, Ishikawa Yuichi, Kawashima Naomi, Akashi Akimi, Adachi Yoshiya, Hattori Hikaru, Ushijima Yoko, Kiyoi Hitoshi

CANCER GENETICS 222 巻頁： 38 - 45 2018年4月

Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography 査読有り国際誌

Sakashita Gyosuke, Kiyoi Hitoshi, Naoe Tomoki, Urano Takeshi

SCIENTIFIC REPORTS 8 巻 ( 1 ) 頁： 4008 2018年3月

Clinical impact of underweight status at diagnosis on elderly patients with acute myeloid leukemia: a retrospective study of JALSG GML200. 査読有り

Harada K, Doki N, Miyazaki Y, Wakita A, Ohtake S, Takada S, Komatsu H, Kubo K, Takeshita A, Adachi Y, Kiyoi H, Yamaguchi T, Yoshida M, Naoe T, Ohashi K

Annals of hematology 2018年3月

High-dose methotrexate therapy significantly improved survival of adult acute lymphoblastic leukemia: a phase III study by JALSG 査読有り国際誌

Sakura T., Hayakawa F., Sugiura I., Murayama T., Imai K., Usui N., Fujisawa S., Yamauchi T., Yujiri T., Kakihana K., Ito Y., Kanamori H., Ueda Y., Miyata Y., Kurokawa M., Asou N., Ohnishi K., Ohtake S., Kobayashi Y., Matsuo K., Kiyoi H., Miyazaki Y., Naoe T.

LEUKEMIA 32 巻 ( 3 ) 頁： 626 - 632 2018年3月

Prognostic analysis according to the 2017 ELN risk stratification by genetics in adult acute myeloid leukemia patients treated in the Japan Adult Leukemia Study Group (JALSG) AML201 study. 査読有り

Harada Y, Nagata Y, Kihara R, Ishikawa Y, Asou N, Ohtake S, Miyawaki S, Sakura T, Ozawa Y, Usui N, Kanamori H, Ito Y, Imai K, Suehiro Y, Kobayashi S, Kitamura K, Sakaida E, Onizuka M, Takeshita A, Ishida F, Suzushima H, Ishizawa K, Naoe T, Matsumura I, Miyazaki Y, Ogawa S, Kiyoi H, Japan Adult Leukemia Study Group JALSG.

Leukemia research 66 巻頁： 20-27 2018年3月

High Incidence of Extensive Chronic Gvhd in Patients with the REG3A Rs7588571 Non-GG Genotype 査読有り

Murata Makoto, Koyama Daisuke, Hanajiri Ryo, Okuno Shingo, Kamoshita Sonoko, Julamanee Jakrawadee, Takagi Erina, Hirano Daiki, Miyao Kotaro, Sakemura Reona, Goto Tatsunori, Hayakawa Fumihiko, Seto Aika, Ozawa Yukiyasu, Miyamura Koichi, Terakura Seitaro, Nishida Tetsuya, Kiyoi Hitoshi

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 24 巻 ( 3 ) 頁： S192-S193 2018年3月

Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study 査読有り国際誌

Kobayashi Tomoko, Iwama Shintaro, Yasuda Yoshinori, Okada Norio, Tsunekawa Taku, Onoue Takeshi, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Morishita Yoshiaki, Goto Motomitsu, Suga Hidetaka, Banno Ryoichi, Yokota Kenji, Hase Tetsunari, Morise Masahiro, Hashimoto Naozumi, Ando Masahiko, Kiyoi Hitoshi, Gotoh Momokazu, Ando Yuichi, Akiyama Masashi, Hasegawa Yoshinori, Arima Hiroshi

JOURNAL OF THE ENDOCRINE SOCIETY 2 巻 ( 3 ) 頁： 241 - 251 2018年3月

Distinct gene alterations with a high percentage of myeloperoxidase-positive leukemic blasts in de novo acute myeloid leukemia. 査読有り

Kamijo R, Itonaga H, Kihara R, Nagata Y, Hata T, Asou N, Ohtake S, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Naoe T, Kiyoi H, Miyazaki Y

Leukemia research 65 巻頁： 34-41 2018年2月

Intrabone single unit cord blood transplantation for hematological malignancies 査読有り

Murata Makoto, Maeda Yoshinobu, Masuko Masayoshi, Fukuhara Noriko, Nishida Tetsuya, Terakura Seitaro, Ishikawa Yuichi, Tanimoto Mitsune, Shibasaki Yasuhiko, Suzuki Ritsuro, Kodera Yoshihisa, Kiyoi Hitoshi, Naoe Tomoki

CANCER SCIENCE 109 巻頁： 757-757 2018年1月

BCR-ABL-specific CD4(+) T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells 査読有り国際誌

Ueda Norihiro, Zhang Rong, Tatsumi Minako, Liu Tian-Yi, Kitayama Shuichi, Yasui Yutaka, Sugai Shiori, Iwama Tatsuaki, Senju Satoru, Okada Seiji, Nakatsura Tetsuya, Kuzushima Kiyotaka, Kiyoi Hitoshi, Naoe Tomoki, Kaneko Shin, Uemura Yasushi

CELLULAR & MOLECULAR IMMUNOLOGY 15 巻 ( 1 ) 頁： 15 - 26 2018年1月

Underweight status at diagnosis is associated with poorer outcomes in adult patients with acute myeloid leukemia: a retrospective study of JALSG AML 201 査読有り国際誌

Harada Kaito, Doki Noriko, Hagino Takeshi, Miyawaki Shuichi, Ohtake Shigeki, Kiyoi Hitoshi, Miyazaki Yasushi, Fujita Hiroyuki, Usui Noriko, Okumura Hirokazu, Miyamura Koichi, Nakaseko Chiaki, Fujieda Atsushi, Nagai Tadashi, Yamane Takahisa, Sakamaki Hisashi, Ohnishi Kazunori, Naoe Tomoki, Ohno Ryuzo, Ohashi Kazuteru

ANNALS OF HEMATOLOGY 97 巻 ( 1 ) 頁： 73 - 81 2018年1月

Identification of the novel deletion-type PML-RARA mutation associated with the retinoic acid resistance in acute promyelocytic leukemia. 査読有り

Hattori H, Ishikawa Y, Kawashima N, Akashi A, Yamaguchi Y, Harada Y, Hirano D, Adachi Y, Miyao K, Ushijima Y, Terakura S, Nishida T, Matsushita T, Kiyoi H

PloS one 13 巻 ( 10 ) 頁： e0204850 2018年

Underweight status at diagnosis is associated with poorer outcomes in adult patients with acute myeloid leukemia: a retrospective study of JALSG AML 201. 査読有り

Harada K, Doki N, Hagino T, Miyawaki S, Ohtake S, Kiyoi H, Miyazaki Y, Fujita H, Usui N, Okumura H, Miyamura K, Nakaseko C, Fujieda A, Nagai T, Yamane T, Sakamaki H, Ohnishi K, Naoe T, Ohno R, Ohashi K

Ann Hematol. 2017年12月

Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia: A study protocol for a multicenter exploratory prospective study (Auto-Ph17 study) 査読有り国際誌

Nishiwaki Satoshi, Sugiura Isamu, Miyata Yasuhiko, Saito Shigeki, Sawa Masashi, Nishida Tetsuya, Miyamura Koichi, Kuwatsuka Yachiyo, Kohno Akio, Yuge Masaaki, Kasai Masanobu, Iida Hiroatsu, Kurahashi Shingo, Osaki Masahide, Goto Tatsunori, Terakura Seitaro, Murata Makoto, Nishikawa Hiroyoshi, Kiyoi Hitoshi

MEDICINE 96 巻 ( 52 ) 頁： e9568 2017年12月

Altered EZH2 splicing and expression is associated with impaired histone H3 lysine 27 tri-Methylation in myelodysplastic syndrome. 査読有り

Shirahata-Adachi M, Iriyama C, Tomita A, Suzuki Y, Shimada K, Kiyoi H.

Leuk Res 63 巻頁： 90-97 2017年11月

Prognostic value of genetic mutations in adolescent and young adults with acute myeloid leukemia. 査読有り

Kuwatsuka Y, Tomizawa D, Kihara R, Nagata Y, Shiba N, Iijima-Yamashita Y, Shimada A, Deguchi T, Miyachi H, Tawa A, Taga T, Kinoshita A, Nakayama H, Kiyokawa N, Saito AM, Koh K, Goto H, Kosaka Y, Asou N, Ohtake S, Miyawaki S, Miyazaki Y, Sakura T, Ozawa Y, Usui N, Kanamori H, Ito Y, Imai K, Suehiro Y, Kobayashi S, Kitamura K, Sakaida E, Ogawa S, Naoe T, Hayashi Y, Horibe K, Manabe A, Mizutani S, Adachi S, Kiyoi H.

Int J Hematol 2017年10月

Identification of volasertib-resistant mechanism and evaluation of combination effects with volasertib and other agents on acute myeloid leukemia. 査読有り

Adachi Y, Ishikawa Y, Kiyoi H.

Oncotarget 8 巻頁： 78452-78465 2017年10月

A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study). 査読有り

Kobayashi T, Nannya Y, Ichikawa M, Oritani K, Kanakura Y, Tomita A, Kiyoi H, Kobune M, Kato J, Kawabata H, Shindo M, Torimoto Y, Yonemura Y, Hanaoka N, Nakakuma H, Hasegawa D, Manabe A, Fujishima N, Fujii N, Tanimoto M, Morita Y, Matsuda A, Fujieda A, Katayama N, Ohashi H, Nagai H, Terada Y, Hino M, Sato K, Obara N, Chiba S, Usuki K, Ohta M, Imataki O, Uemura M, Takaku T, Komatsu N, Kitanaka A, Shimoda K, Watanabe K, Tohyama K, Takaori-Kondo A, Harigae H, Arai S, Miyazaki Y, Ozawa K, Kurokawa M; for National Research Group on Idiopathic Bone Marrow Failure Syndromes.

Am J Hematol 92 巻頁： 1324-1332 2017年9月

High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype.

Koyama D, Murata M, Hanajiri R, Okuno S, Kamoshita S, Julamanee J, Takagi E, Hirano D, Miyao K, Sakemura R, Goto T, Hayakawa F, Seto A, Ozawa Y, Miyamura K, Terakura S, Nishida T, Kiyoi H.

PLoS One12 頁： e0185213 2017年9月

Deeper molecular response is a predictive factor for treatment-free remission after imatinib discontinuation in patients with chronic phase chronic myeloid leukemia: the JALSG-STIM213 study. 査読有り

Takahashi N, Tauchi T, Kitamura K, Miyamura K, Saburi Y, Hatta Y, Miyata Y, Kobayashi S, Usuki K, Matsumura I, Minami Y, Usui N, Fukuda T, Takada S, Ishikawa M, Fujimaki K, Gomyo H, Sasaki O, Ohishi K, Miyake T, Imai K, Suzushima H, Mitsui H, Togitani K, Kiguchi T, Atsuta Y, Ohtake S, Ohnishi K, Kobayashi Y, Kiyoi H, Miyazaki Y, Naoe T; Japan Adult Leukemia Study Group.

Int J Hematol 2017年9月

Clinical effectiveness of geriatric assessment for predicting the tolerability of outpatient chemotherapy in older adults with cancer. 査読有り

Hayashi N, Matsuoka A, Goto H, Gotoh M, Kiyoi H, Kodera Y, Nagino M, Nagashima F, Ando Y.

J Geriatr Oncol 2017年8月

Phase II study of intrabone single unit cord blood transplantation for hematological malignancies. 査読有り

Murata M, Maeda Y, Masuko M, Onishi Y, Endo T, Terakura S, Ishikawa Y, Iriyama C, Ushijima Y, Goto T, Fujii N, Tanimoto M, Kobayashi H, Shibasaki Y, Fukuhara N, Inamoto Y, Suzuki R, Kodera Y, Matsushita T, Kiyoi H, Naoe T, Nishida T.

Cancer Sci 108 巻頁： 1634-1639 2017年6月

MOLECULAR MARKERS PREDICTING RESPONSE TO AZACITIDINE TREATMENT FOR MYELODYSPLASTIC SYNDROMES

Nannya Y., Takeda J., Shiozawa Y., Shiraishi Y., Okuno Y., Kataoka K., Chiba K., Tanaka H., Sanada M., Chiba S., Asou N., Kiyoi H., Imai K., Hirase C., Dobashi N., Kiguchi T., Nakao S., Ohyashiki K., Miyazaki Y., Naoe T., Makishima H., Miyano S., Yoshida K., Ogawa S.

HAEMATOLOGICA 102 巻頁： 98-99 2017年6月

Management of infection during chemotherapy for acute leukemia in Japan: a nationwide questionnaire-based survey by the Japan Adult Leukemia Study Group. 査読有り

Kimura SI, Fujita H, Kato H, Hiramoto N, Hosono N, Takahashi T, Shigeno K, Hatsumi N, Minamiguchi H, Miyatake J, Handa H, Akiyama N, Kanda Y, Yoshida M, Kiyoi H, Miyazaki Y, Naoe T; Japan Adult Leukemia Study Group (JALSG).

Support Care Cancer 25 巻頁： 3515-3521 2017年6月

[I.Genetic Abnormalities Associated with Acute Leukemia and a Development of Molecular Therapies].

Adachi Y, Kiyoi H

Gan to kagaku ryoho. Cancer & chemotherapy 44 巻 ( 5 ) 頁： 380-385 2017年5月

YM155 induces apoptosis through proteasome-dependent degradation of MCL-1 in primary effusion lymphoma. 査読有り

Kojima Y, Hayakawa F, Morishita T, Sugimoto K, Minamikawa Y, Iwase M, Yamamoto H, Hirano D, Imoto N, Shimada K, Okada S, Kiyoi H.

Pharmacol Res 120 巻頁： 242-251 2017年4月

Impact of T-cell chimerism on relapse after cord blood transplantation for hematological malignancies: Nagoya Blood and Marrow Transplantation Group study 査読有り国際誌

Yokohata E., Kuwatsuka Y., Ohashi H., Terakura S., Kawashima N., Seto A., Kurahashi S., Ozawa Y., Goto T., Imahashi N., Nishida T., Miyao K., Sakemura R., Kato T., Sawa M., Kohno A., Sao H., Iida H., Kiyoi H., Naoe T., Miyamura K., Murata M.

BONE MARROW TRANSPLANTATION 52 巻 ( 4 ) 頁： 612 - 614 2017年4月

Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia 査読有り国際誌

Togasaki E., Takeda J., Yoshida K., Shiozawa Y., Takeuchi M., Oshima M., Saraya A., Iwama A., Yokote K., Sakaida E., Hirase C., Takeshita A., Imai K., Okumura H., Morishita Y., Usui N., Takahashi N., Fujisawa S., Shiraishi Y., Chiba K., Tanaka H., Kiyoi H., Ohnishi K., Ohtake S., Asou N., Kobayashi Y., Miyazaki Y., Miyano S., Ogawa S., Matsumura I., Nakaseko C., Naoe T.

BLOOD CANCER JOURNAL 7 巻 ( 4 ) 頁： e559 2017年4月

Retrospective analysis of in vivo recovery and clearance during continuous infusion of recombinant factor VIII products: a single-institution study

Suzuki N., Hirakawa A., Kishimoto M., Kanematsu T., Ogawa M., Kiyoi H., Matsushita T.

HAEMOPHILIA 23 巻 ( 2 ) 頁： 215-221 2017年3月

Emetine elicits apoptosis of intractable B-cell lymphoma cells with MYC rearrangement through inhibition of glycolytic metabolism.

Aoki T, Shimada K, Sakamoto A, Sugimoto K, Morishita T, Kojima Y, Shimada S, Kato S, Iriyama C, Kuno S, Harada Y, Tomita A, Hayakawa F, Kiyoi H.

Oncotarget 8 巻頁： 13085-13098 2017年2月

[Malignant lymphoma with cardiac involvement]. 査読有り

Terakura S, Onji M, Iriyama C, Goto T, Ushijima Y, Shimada K, Ishikawa Y, Nishida T, Hayakawa F, Murata M, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology 58 巻 ( 3 ) 頁： 239 - 242 2017年

A Tet-On Inducible System for Controlling CD19-Chimeric Antigen Receptor Expression upon Drug Administration. 査読有り

Sakemura R, Terakura S, Watanabe K, Julamanee J, Takagi E, Miyao K, Koyama D, Goto T, Hanajiri R, Nishida T, Murata M, Kiyoi H.

Cancer Immunol Res. 4 巻 ( 8 ) 頁： 658-68 2016年8月

SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. 査読有り

Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, Hayakawa F, Tomita A, Kiyoi H.

Cancer Sci. 頁： [Epub ahead of print] 2016年6月

PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation. 査読有り

Inagaki Y, Hayakawa F, Hirano D, Kojima Y, Morishita T, Yasuda T, Naoe T, Kiyoi H.

Biochem Biophys Res Commun. 475 巻 ( 2 ) 頁： 176-81 2016年6月

Peripheral blood cell-free DNA is an alternative tumor DNA source reflecting disease status in myelodysplastic syndromes. 査読有り

Suzuki Y, Tomita A, Nakamura F, Iriyama C, Shirahata-Adachi M, Shimada K, Akashi A, Ishikawa Y, Kaneda N, Kiyoi H.

Cancer Sci. 頁： [Epub ahead of print] 2016年6月

Co-expression of wild-type FLT3 attenuates the inhibitory effect of FLT3 inhibitor on FLT3 mutated leukemia cells. 査読有り

Chen F, Ishikawa Y, Akashi A, Naoe T, Kiyoi H.

Oncotarget. 頁： [Epub ahead of print] 2016年6月

Live-cell single-molecule imaging of the cytokine receptor MPL for analysis of dynamic dimerization. 査読有り

Sakamoto A, Tsukamoto T, Furutani Y, Sudo Y, Shimada K, Tomita A, Kiyoi H, Kato T, Funatsu T.

J Mol Cell Biol. 頁： [Epub ahead of print] 2016年6月

BCR-ABL-specific CD4+ T-helper cells promote the priming of antigen-specific cytotoxic T cells via dendritic cells. 査読有り

Ueda N, Zhang R, Tatsumi M, Liu TY, Kitayama S, Yasui Y, Sugai S, Iwama T, Senju S, Okada S, Nakatsura T, Kuzushima K, Kiyoi H, Naoe T, Kaneko S, Uemura Y.

Cell Mol Immunol 頁： [Epub ahead of print] 2016年5月

Identification of Meflin as a Potential Marker for Mesenchymal Stromal Cells. 査読有り

Maeda K, Enomoto A, Hara A, Asai N, Kobayashi T, Horinouchi A, Maruyama S, Ishikawa Y, Nishiyama T, Kiyoi H, Kato T, Ando K, Weng L, Mii S, Asai M, Mizutani Y, Watanabe O, Hirooka Y, Goto H, Takahashi M.

Sci Rep. 6 巻頁： 22288 2016年2月

B Cell Linker Protein (BLNK) Is a Selective Target of Repression by PAX5-PML Protein in the Differentiation Block That Leads to the Development of Acute Lymphoblastic Leukemia. 査読有り

Imoto N, Hayakawa F, Kurahashi S, Morishita T, Kojima Y, Yasuda T, Sugimoto K, Tsuzuki S, Naoe T, Kiyoi H.

J Biol Chem. 291 巻 ( 9 ) 頁： 4723-31 2016年2月

The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese. 査読有り

Kishimoto M, Suzuki N, Murata M, Ogawa M, Kanematsu T, Takagi A, Kiyoi H, Kojima T, Matsushita T.

Ann Hematol. 95 巻 ( 3 ) 頁： 541-2 2016年2月

A case of MYH9 disorders caused by a novel mutation (p.K74E). 査読有り

Kanematsu T, Suzuki N, Yoshida T, Kishimoto M, Aoki T, Ogawa M, Kagami Y, Kiyoi H, Matsushita T, Kunishima S.

Ann Hematol 95 巻 ( 1 ) 頁： 161-3 2016年1月

Clinical usefulness of WT1 mRNA expression in bone marrow detected by a new WT1 mRNA assay kit for monitoring acute myeloid leukemia: a comparison with expression of WT1 mRNA in peripheral blood. 査読有り

Kitamura K, Nishiyama T, Ishiyama K, Miyawaki S, Miyazaki K, Suzuki K, Masaie H, Okada M, Ogawa H, Imai K, Kiyoi H, Naoe T, Yokoyama Y, Chiba S, Hata T, Miyazaki Y, Hatta Y, Takeuchi J, Nannya Y, Kurokawa M, Ueda Y, Koga D, Sugiyama H, Takaku F.

Int J Hematol. 103 巻 ( 1 ) 頁： 53-62 2016年1月

High-dose chemotherapy followed by autologous stem cell transplantation for relapsed/refractory primary mediastinal large B-cell lymphoma. 査読有り

Aoki T, Shimada K, Suzuki R, Izutsu K, Tomita A, Maeda Y, Takizawa J, Mitani K, Igarashi T, Sakai K, Miyazaki K, Mihara K, Ohmachi K, Nakamura N, Takasaki H, Kiyoi H, Nakamura S, Kinoshita T, Ogura M.

Blood Cancer J. 5 巻頁： e372 2015年12月

Overview: A New Era of Cancer Genome in Myeloid Malignancies. 招待有り査読有り

Kiyoi H.

Oncology. 89 巻 ( Suppl 1 ) 頁： 1-3 2015年11月

Phase I trial of volasertib, a Polo-like kinase inhibitor, in Japanese patients with acute myeloid leukemia. 査読有り

Kobayashi Y, Yamauchi T, Kiyoi H, Sakura T, Hata T, Ando K, Watabe A, Harada A, Taube T, Miyazaki Y, Naoe T.

Cancer Sci. 106 巻 ( 11 ) 頁： 1590-5 2015年11月

Target Antigen Density Governs the Efficacy of Anti-CD20-CD28-CD3 ζ Chimeric Antigen Receptor-Modified Effector CD8+ T Cells. 査読有り

Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M.

J Immunol. 194 巻頁： 911-20 2015年

Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells. 査読有り

Sugimoto K, Hayakawa F, Shimada S, Morishita T, Shimada K, Katakai T, Tomita A, Kiyoi H, Naoe T.

Sci Rep. 5 巻頁： 13054 2015年

Integration of humoral and cellular HLA-specific immune responses in cord blood allograft rejection. 査読有り

Hanajiri R, Murata M, Sugimoto K, Murase M, Sakemura R, Goto T, Watanabe K, Imahashi N, Terakura S, Ohashi H, Akatsuka Y, Kurahashi S, Miyamura K, Kiyoi H, Nishida T, Naoe T.

Bone Marrow Transplant 50 巻頁： 1187-94 2015年

FLT3 Inhibitors: Recent Advances And Problems For Clinical Application. 招待有り査読有り

Kiyoi H

Nagoya J Med Sci 77 巻頁： 7-17 2015年

Chimerism status after unrelated donor bone marrow transplantation with fludarabine-melphalan conditioning is affected by the melphalan dose and is predictive of relapse. 査読有り

Imahashi N, Ohashi H, Terakura S, Miyao K, Sakemura R, Kato T, Sawa M, Yokohata E, Kurahashi S, Ozawa Y, Nishida T, Kiyoi H, Watamoto K, Kohno A, Kasai M, Kato C, Iida H, Naoe T, Miyamura K, Murata M; for the Nagoya Blood and Marrow Transplantation Group.

Ann Hematol 94 巻頁： 1139-48 2015年

Simple and Efficient Generation of Virus-specific T Cells for Adoptive Therapy Using Anti-4-1BB Antibody. 査読有り

Imahashi N, Nishida T, Goto T, Terakura S, Watanabe K, Hanajiri R, Sakemura R, Imai M, Kiyoi H, Naoe T, Murata M.

J Immunother. 38 巻頁： 62-70 2015年

Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group. 査読有り

Hayakawa F, Sakura T, Yujiri T, Kondo E, Fujimaki K, Sasaki O, Miyatake J, Handa H, Ueda Y, Aoyama Y, Takada S, Tanaka Y, Usui N, Miyawaki S, Suenobu S, Horibe K, Kiyoi H, Ohnishi K, Miyazaki Y, Ohtake S, Kobayashi Y, Matsuo K, Naoe T; Japan Adult Leukemia Study Group (JALSG).

Blood Cancer J. 4 巻頁： e252 2014年10月

Efficacy of ofatumumab against rituximab-resistant B-CLL/SLL cells with low CD20 protein expression. 査読有り

Shimada K, Tomita A, Saito S, Kiyoi H.

Br J Haematol 166 巻頁： 455-457 2014年

Expression of CD56 is an unfavorable prognostic factor for acute promyelocytic leukemia with higher initial white blood cell counts. 査読有り

Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Yamauchi T, Emi N, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Kimura Y, Iwanaga M, Asou N, Naoe T; The Japan Adult Leukemia Study Group.

Cancer Sci 105 巻頁： 97-104 2014年

De novo diffuse large B-cell lymphoma with a CD20 immunohistochemistry-positive and flow cytometry-negative phenotype: Molecular mechanisms and correlation with rituximab sensitivity. 査読有り

Tokunaga T, Tomita A, Sugimoto K, Shimada K, Iriyama C, Hirose T, Shirahata-Adachi M, Suzuki Y, Mizuno H, Kiyoi H, Asano N, Nakamura S, Kinoshita T, Naoe T.

Cancer Sci 105 巻頁： 35-43 2014年

The demarcation between younger and older acute myeloid leukemia patients: a pooled analysis of 3 prospective studies. 査読有り

Yanada M, Ohtake S, Miyawaki S, Sakamaki H, Sakura T, Maeda T, Miyamura K, Asou N, Oh I, Miyatake J, Kanbayashi H, Takeuchi J, Takahashi M, Dobashi D, Kiyoi H, Miyazaki Y, Emi N, Kobayashi Y, Ohno R, Naoe T.

Cancer ( 119 ) 頁： in press 2013年

GATA2 zinc finger 2 mutation found in acute myeloid leukemia impairs myeloid differentiation. 査読有り

Niimi K, Kiyoi H, Ishikawa Y, Hayakawa F, Kurahashi S, Kihara R, Tomita A and Naoe T.

Leukemia Research Reports 2 巻頁： 21-25 2013年

Mutations in the nucleolar phosphoprotein, nucleophosmin, promote the expression of the oncogenic transcription factor MEF/ELF4 in leukemia cells and potentiates transformation. 査読有り

Ando K, Tsushima H, Matsuo E, Horio K, Tominaga-Sato S, Imanishi D, Imaizumi Y, Iwanaga M, Itonaga H, Yoshida S, Hata T, Moriuchi R, Kiyoi H, Nimer S, Mano H, Naoe T, Tomonaga M, Miyazaki Y.

J Biol Chem 288 巻頁： 9457-9467 2013年

Gene mutations of acute myeloid leukemia in the genome era. 招待有り査読有り

Naoe T, Kiyoi H

Int J Hematol 97 巻頁： 165-174 2013年

Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97. 査読有り

Fujita H, Asou N, Iwanaga M, Hyo R, Nomura S, Kiyoi H, Okada M, Inaguma Y, Matsuda M, Yamauchi T, Ohtake S, Izumi T, Nakaseko C, Ishigatsubo Y, Shinagawa K, Takeshita A, Miyazaki Y, Ohnishi K, Miyawaki S, Naoe T; Japan Adult Leukemia Study Group.

Cancer Sci 104 巻頁： 1339-45 2013年

Mechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) in acute promyelocytic leukemia. 招待有り査読有り

Tomita A, Kiyoi H, Naoe T.

Int J Hematol 97 巻頁： 717-725 2013年

Guest editorial: efficacy of and resistance to molecularly targeted therapy for myeloid malignancies. 招待有り査読有り

Kiyoi H.

Int J Hematol 97 巻頁： 681-682 2013年

CML cells expressing the TEL/MDS1/EVI1 fusion are resistant to imatinib-induced apoptosis through inhibition of BAD, but are resensitized with ABT-737. 査読有り

Shimada K, Tomita A, Minami Y, Abe A, Hind CK, Kiyoi H, Cragg MS, Naoe T.

Exp Hematol 40 巻頁： 724-737 2012年

Randomized comparison of fixed-schedule versus response-oriented individualized induction therapy and use of ubenimex during and after consolidation therapy for elderly patients with acute myeloid leukemia: the JALSG GML200 Study. 査読有り

Wakita A, Ohtake S, Takada S, Yagasaki F, Komatsu H, Miyazaki Y, Kubo K, Kimura Y, Takeshita A, Adachi Y, Kiyoi H, Yamaguchi T, Yoshida M, Ohnishi K, Miyawaki S, Naoe T, Ueda R, Ohno R.

Int J Hematol 96 巻頁： 84-93 2012年

Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia. 査読有り

Doisaki S, Muramatsu H, Shimada A, Takahashi Y, Mori-Ezaki M, Sato M, Kawaguchi H, Kinoshita A, Sotomatsu M, Hayashi Y, Furukawa-Hibi Y, Yamada K, Hoshino H, Kiyoi H, Yoshida N, Sakaguchi H, Narita A, Wang X, Ismael O, Xu Y, Nishio N, Tanaka M, Hama A, Koike K, Kojima S.

Blood 120 巻頁： 1485-8 2012年

Long-term outcome and prognostic factors of elderly patients with acute promyelocytic leukemia. 査読有り

Ono T, Takeshita A, Kishimoto Y, Kiyoi H, Okada M, Yamauchi T, Tsuzuki M, Horikawa K, Matsuda M, Shinagawa K, Monma F, Ohtake S, Nakaseko C, Takahashi M, Kimura Y, Iwanaga M, Asou N, Naoe T.

Cancer Sci 103 巻 ( 11 ) 頁： 1974-1978 2012年

Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome. 査読有り

Iriyama C, Tomita A, Hoshino H, Shirahata M, Furukawa-Hibi Y, Yamada K, Kiyoi H, Naoe T.

Biochem Biophys Res Commun 419 巻頁： 662-9 2012年

Molecular lesions in childhood and adult acute megakaryoblastic leukaemia.

Hama A, Muramatsu H, Makishima H, Sugimoto Y, Szpurka H, Jasek M, O'Keefe C, Takahashi Y, Sakaguchi H, Doisaki S, Shimada A, Watanabe N, Kato K, Kiyoi H, Naoe T, Kojima S, Maciejewski JP.

Br J Haematol 156 巻頁： 316-325 2012年

Y654 of β-catenin is essential for FLT3/ITD-related tyrosine phosphorylation and nuclear localization of β-catenin. 査読有り

Kajiguchi T, Katsumi A, Tanizaki R, Kiyoi H, Naoe T

Eur J Haematol 88 巻頁： 314-20 2012年

Long-term outcome of imatinib therapy, with assessment of its dosage and blood levels, for chronic myelogenous leukemia. 査読有り

Ohnishi K, Nakaseko C, Takeuchi J, Fujisawa S, Nagai T, Yamazaki H, Tauchi T, Imai K, Mori N, Yagasaki F, Maeda Y, Usui N, Miyazaki Y, Miyamura K, Kiyoi H, Ohtake S, Naoe T.

Cancer Sci 103 巻頁： 1071-1078 2012年

Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: JALSG AML201 Study. 査読有り

Ohtake S, Miyawaki S, Fujita H, Kiyoi H, Shinagawa K, Usui N, Okumura H, Miyamura K, Nakaseko C, Miyazaki Y, Fujieda A, Nagai T, Yamane T, Taniwaki M, Takahashi M, Yagasaki F, Kimura Y, Asou N, Sakamaki H, Handa H, Honda S, Ohnishi K, Naoe T, Ohno R.

Blood 117 巻 ( 117 ) 頁： 2358-2365 2011年

FLT3/ITD regulates leukaemia cell adhesion through α4β1 integrin and Pyk2 signaling. 査読有り

Katsumi A, Kiyoi H, Abe A, Tanizaki R, Iwasaki T, Kobayashi M, Matsushita T, Senga T, Kohno T, Kojima T, Kaibuchi K, Hamaguchi M, Naoe T.

Eur J Haematol 86 巻頁： 191-198 2011年

A novel insertion mutation of K294RGG within BCR-ABL kinase domain confers imatinib-resistance: sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis. 査読有り

Sakai K, Ishikawa Y, Mori Y, Kobayashi M, Iriyama C, Ozawa Y, Suzuki T, Minami Y, Ishikawa K, Kaneda N, Naoe T, Kiyoi H.

Int J Hematol 93 巻頁： 237-242 2011年

Virus-associated hemophagocytic syndrome caused by pandemic swine-origin influenza A (H1N1) in a patient after unrelated bone marrow transplantation. 査読有り

Katsumi A, Nishida T, Murata M, Terakura S, Shimada K, Saito S, Kobayashi M, Kodaira A, Shibata S, Oda I, Yagi T, Kiyoi H, Matsushita T, Kojima T, Naoe T.

J Clin Exp Hematop 51 巻頁： 63-65 2011年

Phase I trial of gemtuzumab ozogamicin in intensive combination chemotherapy for relapsed or refractory adult acute myeloid leukemia (AML): Japan Adult Leukemia Study Group (JALSG)-AML206 study. 査読有り

Usui N, Takeshita A, Nakaseko C, Dobashi N, Fujita H, Kiyoi H, Kobayashi Y, Sakura T, Yahagi Y, Shigeno K, Ohwada C, Miyazaki Y, Ohtake S, Miyawaki S, Naoe T, Ohnishi K

Cancer Sci 102 巻頁： 1358-1365 2011年

Prevalence and clinical characteristics of N-terminally truncated WT1 expression in acute myeloid leukemia. 査読有り

Ishikawa Y, Kiyoi H, Naoe T.

Leuk Res 35 巻頁： 685-688 2011年

A randomized comparison of four courses of standard-dose multiagent chemotherapy versus three courses of high-dose cytarabine alone in post-remission therapy for acute myeloid leukemia in adults: the JALSG AML201 study. 査読有り

Miyawaki S, Ohtake S, Fujisawa S, Kiyoi H, Shinagawa K, Usui N, Sakura T, Miyamura K, Nakaseko C, Miyazaki Y, Fujieda A, Nagai T, Yamane T, Taniwaki M, Takahashi M, Yagasaki F, Kimura Y, Asou N, Sakamaki H, Handa H, Honda S, Ohnishi K, Naoe T, Ohno R.

Blood 117 巻頁： 2366-2372 2011年

Trough plasma concentration of imatinib reflects BCR-ABL kinase inhibitory activity and clinical response in chronic-phase chronic myeloid leukemia: a report from the BINGO study. 査読有り

Ishikawa Y, Kiyoi H, Watanabe K, Miyamura K, Nakano Y, Kitamura K, Kohno A, Sugiura I, Yokozawa T, Hanamura A, Yamamoto K, Iida H, Emi N, Suzuki R, Ohnishi K, Naoe T.

Cancer Sci 101 巻頁： 2186-2192 2010年10月

Imatinib for newly diagnosed chronic-phase chronic myeloid leukemia: results of a prospective study in Japan. 査読有り

Nagai T, Takeuchi J, Dobashi N, Kanakura Y, Taniguchi S, Ezaki K, Nakaseko C, Hiraoka A, Okada M, Miyazaki Y, Motoji T, Higashihara M, Tsukamoto N, Kiyoi H, Nakao S, Shinagawa K, Ohno R, Naoe T, Ohnishi K, Usui N.

Int J Hematol 92 巻頁： 111-117 2010年7月

Array-based genomic resequencing of human leukemia. 査読有り

Yamashita Y, Yuan J, Suetake I, Suzuki H, Ishikawa Y, Choi YL, Ueno T, Soda M, Hamada T, Haruta H, Takada S, Miyazaki Y, Kiyoi H, Ito E, Naoe T, Tomonaga M, Toyota M, Tajima S, Iwama A, Mano H.

Oncogene 29 巻頁： 3723-3731 2010年6月

BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4. 査読有り

Suzuki M, Abe A, Imagama S, Nomura Y, Tanizaki R, Minami Y, Hayakawa F, Ito Y, Katsumi A, Yamamoto K, Emi N, Kiyoi H, Naoe T.

Eur J Haematol 84 巻頁： 229-238 2010年

Selective KIT inhibitor KI-328 and HSP90 inhibitor show different potency against the type of KIT mutations recurrently identified in acute myeloid leukemia. 査読有り

Tsujimura A, Kiyoi H, Shiotsu Y, Ishikawa Y, Mori Y, Ishida H, Toki T, Ito E, Naoe T.

Int J Hematol 92 巻 2010年

Phase I study of KW-0761, a defucosylated humanized anti-CCR4 antibody, in relapsed patients with adult T-cell leukemia-lymphoma and peripheral T-cell lymphoma. 査読有り

Yamamoto K, Utsunomiya A, Tobinai K, Tsukasaki K, Uike N, Uozumi K, Yamaguchi K, Yamada Y, Hanada S, Tamura K, Nakamura S, Inagaki H, Ohshima K, Kiyoi H, Ishida T, Matsushima K, Akinaga S, Ogura M, Tomonaga M, Ueda R.

J Clin Oncol 28 巻頁： 1591-1598 2010年

Randomized trial of response-oriented individualized versus fixed-schedule induction chemotherapy with idarubicin and cytarabine in adult acute myeloid leukemia: the JALSG AML95 study. 査読有り

Ohtake S, Miyawaki S, Kiyoi H, Miyazaki Y, Okumura H, Matsuda S, Nagai T, Kishimoto Y, Okada M, Takahashi M, Handa H, Takeuchi J, Kageyama S, Asou N, Yagasaki F, Maeda Y, Ohnishi K, Naoe T, Ohno R.

Int J Hematol 91 巻頁： 276-283 2010年

Irrespective of CD34 expression, lineage-committed cell fraction reconstitutes and re-establishes transformed Philadelphia chromosome-positive leukemia in NOD / SCID / IL-2Rgammac mice. 査読有り

Tanizaki R, Nomura Y, Miyata Y, Minami Y, Abe A, Hanamura A, Sawa M, Murata M, Kiyoi H, Matsushita T, Naoe T.

Cancer Sci 101 巻頁： 631-638 2010年

Expanded distribution of the T315I mutation among hematopoietic stem cells and progenitors in a chronic myeloid leukemia patient during imatinib treatment. 査読有り

Minami Y, Kajiguchi T, Abe A, Ohno T, Kiyoi H, Naoe T.

Int J Hematol 92 巻頁： 664-666 2010年

Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance. 査読有り

Hiraga J, Tomita A, Sugimoto T, Shimada K, Ito M, Nakamura S, Kiyoi H, Kinoshita T, Naoe T.

Blood 113 巻頁： 4885-4893 2009年

Donor single nucleotide polymorphism in the CCR9 gene affects the incidence of skin GVHD. 査読有り

Inamoto Y, Murata M, Katsumi A, Kuwatsuka Y, Tsujimura A, Ishikawa Y, Sugimoto K, Onizuka M, Terakura S, Nishida T, Kanie T, Taji H, Iida H, Suzuki R, Abe A, Kiyoi H, Matsushita T, Miyamura K, Kodera Y, Naoe T.

Bone Marrow Transplant 45 巻頁： 363-369 2009年

Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation. 査読有り

Sugimoto T, Tomita A, Hiraga J, Shimada K, Kiyoi H, Kinoshita T, Naoe T.

Biochem Biophys Res Commun 390 巻頁： 48-53 2009年

CMC-544 (inotuzumab ozogamicin) shows less effect on multidrug resistant cells: analyses in cell lines and cells from patients with B-cell chronic lymphocytic leukaemia and lymphoma. 査読有り

Takeshita A, Shinjo K, Yamakage N, Ono T, Hirano I, Matsui H, Shigeno K, Nakamura S, Tobita T, Maekawa M, Ohnishi K, Sugimoto Y, Kiyoi H, Naoe T, Ohno R.

Br J Haematol 146 巻頁： 34-43 2009年

CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells. 査読有り

Takeshita A, Yamakage N, Shinjo K, Ono T, Hirano I, Nakamura S, Shigeno K, Tobita T, Maekawa M, Kiyoi H, Naoe T, Ohnishi K, Sugimoto Y, Ohno R.

Leukemia 23 巻頁： 1329-1336 2009年

Comprehensive analysis of cooperative gene mutations between class I and class II in de novo acute myeloid leukemia. 査読有り

Ishikawa Y, Kiyoi H, Tsujimura A, Miyawaki S, Miyazaki Y, Kuriyama K, Tomonaga M, Naoe T.

Eur J Haematol 83 巻頁： 90-98 2009年

Clinical significance of nuclear non-phosphorylated beta-catenin in acute myeloid leukaemia and myelodysplastic syndrome. 査読有り

10. Xu J, Suzuki M, Niwa Y, Hiraga J, Nagasaka T, Ito M, Nakamura S, Tomita A, Abe A, Kiyoi H, Kinoshita T, Naoe T.

Br J Haematol. 140 巻頁： 394-401 2008年

Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan. 査読有り

Narimatsu H, Iino M, Ichihashi T, Yokozawa T, Hayakawa M, Kiyoi H, Takeo T, Sawamoto A, Iida H, Tsuzuki M, Yanada M, Naoe T, Suzuki R, Sugiura I.

Int J Hematol 88 巻 2008年

Karyotypically independent clones with del(11q) and trisomy 10 in acute myeloid leukemia: trisomy 10 may appear as an additional change. 査読有り

Gotoh M, Sasaki Y, Iguchi T, Fujimoto H, Kodama A, Kiyoi H, Naoe T, Ohyashiki K.

Int J Hematol 88 巻頁： 123-124 2008年

Donor cell leukemia after allogeneic peripheral blood stem cell transplantation: a case report and literature review. 査読有り

Murata M, Ishikawa Y, Ohashi H, Terakura S, Ozeki K, Kiyoi H, Naoe T.

Int J Hematol 88 巻頁： 111-115 2008年

Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome. 査読有り

Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kanegane H, Miura M, Adachi S, Migita M, Morinaga S, Nakano T, Endo M, Kojima S, Kiyoi H, Mano H, Ito E.

Br J Haematol. 141 巻頁： 681-688 2008年

Mutations of JAK2, JAK3 and GATA1 in acute megakaryoblastic leukemia of Down syndrome. 査読有り

8. Hama A, Yagasaki H, Takahashi Y, Matsumoto K, Kiyoi H, Kojima S.

Blood 111 巻頁： 2493-2494 2008年

Clinical characteristics and outcomes in patients with t(8;21) acute myeloid leukemia in Japan. 査読有り

9. Narimatsu H, Yokozawa T, Iida H, Tsuzuki M, Hayakawa M, Takeo T, Iino M, Ichihashi T, Kato C, Sawamoto A, Sao H, Yanada M, Emi N, Kiyoi H, Yamaguchi T, Naoe T, Suzuki R, Sugiura I.

Leukemia 22 巻頁： 432-434 2008年

Novel and orally active 5-(1,3,4-oxadiazol-2-yl)pyrimidine derivatives as selective FLT3 inhibitors. 査読有り

Ishida H, Isami S, Matsumura T, Umehara H, Yamashita Y, Kajita J, Fuse E, Kiyoi H, Naoe T, Akinaga S, Shiotsu Y, Arai H.

Bioorg Med Chem Lett. 18 巻頁： 5472-5477 2008年

Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. 査読有り

Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CH, Wang JY, Naoe T.

Int J Hematol 88 巻頁： 471-475 2008年

Prognostic implication and biological roles of RhoH in acute myeloid leukaemia. 査読有り

Iwasaki T, Katsumi A, Kiyoi H, Tanizaki R, Ishikawa Y, Ozeki K, Kobayashi M, Abe A, Matsushita T, Watanabe T, Amano M, Kojima T, Kaibuchi K, Naoe T.

Eur J Haematol 81 巻頁： 454-460 2008年

Mutational analysis of SOS1 gene in acute myeloid leukemia. 査読有り

Tanizaki R, Katsumi A, Kiyoi H, Kunishima S, Iwasaki T, Ishikawa Y, Kobayashi M, Abe A, Matsushita T, Watanabe T, Kojima T, Kaibuchi K, Kojima S, Naoe T.

Int J Hematol 88 巻 2008年

Clinical features and outcome of T-lineage acute lymphoblastic leukemia in adults: A low initial white blood cell count, as well as a high count predict decreased survival rates. 査読有り

Yanada M, Jinnai I, Takeuchi J, Ueda T, Miyawaki S, Tsuzuki M, Hatta Y, Usui N, Wada H, Morii T, Matsuda M, Kiyoi H, Okada M, Honda S, Miyazaki Y, Ohno R, Naoe T.

Leukemia Res 31 巻 2007年

FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells. 査読有り

Kajiguchi T, Chung EJ, Lee S, Stine A, Kiyoi H, Naoe T, Levis MJ, Neckers L, Trepel JB.

Leukemia 21 巻 2007年

Clinical characteristics and outcomes in patients with t(8;21) acute myeloid leukemia in Japan. 査読有り

Narimatsu H, Yokozawa T, Iida H, Tsuzuki M, Hayakawa M, Takeo T, Iino M, Ichihashi T, Kato C, Sawamoto A, Sao H, Yanada M, Emi N, Kiyoi H, Yamaguchi T, Naoe T, Suzuki R, Sugiura I.

Leukemia 21 巻 2007年

High incidence of secondary failure of platelet recovery after autologous and syngeneic peripheral blood stem cell transplantation in acute promyelocytic leukemia. 査読有り

Narimatsu H, Emi N, Kohno A, Iwai M, Yanada M, Yokozawa T, Saito S, Shimada K, Kiyoi H, Naoe T, Yamamoto K, Morishita Y.

Bone Marrow Transplant 40 巻 2007年

Prognostic analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma. 査読有り

Hiraga J, Katsumi A, Iwasaki T, Abe A, Kiyoi H, Matsushita T, Kinoshita T, Naoe T.

Leukemia 21 巻 2007年

Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. 査読有り

Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T.

Leukemia 21 巻頁： 136 2007年

Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. 査読有り

Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T.

Leukemia 21 巻頁： 403 2007年

JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults. 査読有り

Kiyoi H, Yamaji S, Kojima, Naoe T.

Leukemia 21 巻頁： 574 2007年

Epegenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with Rituximab-containing chemotherapy. 査読有り

Tomita A, Hiraga J, Kiyoi H, Ninomiya M, Sugimoto T, Ito M, Kinoshita T, Naoe T.

Int J Hematol 84 巻 2007年

A novel FLT3 inhibitor FI-700 selectively suppress the growth of leukemia cells with FLT3 mutations. 査読有り

Kiyoi H, Shiotsu Y, Ozeki K, Yamaji S, Kosugi H, Umehara H, Arai H, Ishii K, Akinaga S, Naoe T.

Clin Cancer Res 13 巻頁： 4575-4582 2007年

Successful second cord blood transplantation using fludarabine and cyclophosphamide as a preparative regimen for graft rejection following reduced-intensity cord blood transplantation. 査読有り

Mizutani E, Narimatsu H, Murata M, Tomita A, Kiyoi H, Naoe T.

Bone Marrow Tranaplant 32 巻 2007年

A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RAR{alpha} transcript after consolidation therapy: The Japan Adult Leukemia Study Group (JALSG) APL97 study. 査読有り

Asou N, Kishimoto Y, Kiyoi H, Okada M, Kawai Y, Tsuzuki M, Horikawa K, Matsuda M, Shinagawa K, Kobayashi T, Ohtake S, Nishimura M, Takahashi M, Yagasaki F, Takeshita A, Kimura Y, Iwanaga M, Naoe T, Ohno R.

Blood 107 巻 2007年

LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). 査読有り

Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T.

Eur J Haematol. 78 巻 2007年

Histone deacetylase 3 (HDAC3) is recruited to target promoters by PML-RARalpha as a component of the N-CoR co-repressor complex to repress transcription in vivo. 査読有り

Atsumi A, Tomita A, Kiyoi H, Naoe T.

BBRC 345 巻頁： 1471 2006年

FLT3 mutations in acute myeloid leukemia. 招待有り査読有り

Kiyoi H, Naoe T.

Meth Molec Med 125 巻頁： 189 2006年

PTPN11, RAS and FLT3 mutations in childhood acute lymphoblastic leukemia. 査読有り

Yamamoto T, Isomura M, Xu Y, Liang J, Yagasaki H, Kamachi Y, Kudo K, Kiyoi H, Naoe T, Kojma S.

Leukemia Res 30 巻頁： 1085 2006年

Mutations of N-RAS, FLT3 and p53 genes are not involved in the development of acute leukemia transformed from myeloproliferative diseases with JAK2 mutation. 査読有り

Suzuki M, Abe A, Kiyoi H, Murata M, Ito Y, Shimada K, Morishita Y, Kinoshita T, Naoe T.

Leukemia 20 巻頁： 1168 2006年

Micafungin, a novel antifungal agent, as empirical therapy in acute leukemia patients with febrile neutropenia. 査読有り

Yanada M, Kiyoi H, Murata M, Suzuki M, Iwai M, Yokozawa T, Baba H, Emi N, Naoe T.

Intern Med 45 巻頁： 259 2006年

Biology, clinical relevance, and moleculary targeted therapy in acute leukemia with FLT3 mutations. 招待有り査読有り

Kiyoi H, Naoe T.

Int J Hematol 83 巻頁： 301 2006年

Establishment of a Stroma-Dependent Human Acute Myelomonocytic Leukemia Cell Line, NAMO-2, with FLT3 Tandem Duplication. 査読有り

Abe A, Kiyoi H, Ninomiya M, Yamazaki T, Murase T, Ozeki K, Suzuki M, Hayakawa F, Katsumi A, Emi N, Naoe T.

Int J Hematol 84 巻頁： 328 2006年

Genomewide array-based comparative genomic hybridization analysis of acute promyelocytic leukemia. 査読有り

Karnan S, Tsuzuki S, Kiyoi H, Tagawa H, Ueda R, Seto M, Naoe T.

Gene Chromosome Canc 45 巻頁： 420 2006年

Disseminated intravascular coagulation in acute leukemia: clinical and laboratory features at presentation. 査読有り

Yanada M, Matsushita T, Suzuki M, Kiyoi H, Yamamoto K, Kinoshita T, Kojima T, Saito H, Naoe T.

Eur J Haematol 77 巻頁： 282 2006年

Nucleophosmin: a versatile molecule associated with hematological malignancies. 査読有り

Naoe T, Suzuki T, Kiyoi H, Urano T.

Cancer Sci 97 巻頁： 963 2006年

Establishment of a myeloid leukemia cell line, TRL-01, with MLL-ENL fusion gene. 査読有り

Ninomiya M, Abe A, Yokozawa T, Ozeki K, Yamamoto K, Ito M, Ito M, Kiyoi H, Emi N, Naoe T.

Cancer Genet Cytogen 169 巻頁： 1 2006年

*Clinical characteristics and prognostic implications of NPM1 mutations in acute myeloid leukemia. 査読有り

Suzuki T, Kiyoi H, Ozeki K, Tomita A, Yamaji S, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Ueda R, Kinoshita T, Emi N, Naoe T.

Blood 106 巻頁： 2854 2005年

Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome. 査読有り

Iwai M, Kiyoi H, Ozeki K, Kinoshita T, Emi N, Ohno R, Naoe T.

Leukemia 19 巻頁： 1367 2005年

Prognostic significance of FLT3 internal tandem duplication and tyrosine kinase domain mutations for acute myeloid leukemia: a meta-analysis. 査読有り

Yanada M, Matsuo K, Suzuki T, Kiyoi H, Naoe T.

Leukemia 19 巻頁： 1345 2005年

Clinical significance of FLT3 in leukemia. 招待有り査読有り

Kiyoi H, Yanada M, Ozeki K.

Int J Hematol 82 巻頁： 85 2005年

BMI-1 Is Highly Expressed in M0-Subtype Acute Myeloid Leukemia. 査読有り

Sawa M, Yamamoto K, Yokozawa T, Kiyoi H, Hishida A, Kajiguchi T, Seto M, Kohno A, Kitamura K, Itoh Y, Asou N, Hamajima N, Emi N, Naoe T.

Int J Hematol 82 巻頁： 42 2005年

Long-term outcomes for unselected patients with acute myeloid leukemia categorized according to the World Health Organization classification: a single-center experience. 査読有り

Yanada M, Suzuki M, Kawashima K, Kiyoi H, Kinoshita T, Emi N, Saito H, Naoe T.

Eur J Haematol 74 巻頁： 418 2005年

*Biological and clinical significance of the FLT3 transcript level in acute myeloid leukemia. 査読有り

Ozeki K, Kiyoi H, Hirose Y, Iwai M, Ninomiya M, Kodera Y, Miyawaki S, Kuriyama K, Shimazaki C, Akiyama H, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Ueda R, Ohno R, Emi N, Naoe T.

Blood 103 巻頁： 1901 2004年

Multiplex real-time RT-PCR for prospective evaluation of WT1 and fusion gene transcripts in newly diagnosed de novo acute myeloid leukemia. 査読有り

Yanada M, Terakura S, Yokozawa T, Yamamoto K, Kiyoi H, Emi N, Kitamura K, Kohno A, Tanaka M, Tobita T, Takeo T, Sao H, Kataoka T, Kobayashi M, Takeshita A, Morishita Y, Sugiura I, Naoe T.

Leukemia Lymphoma 45 巻頁： 1803 2004年

Retinoic acid syndrome in NOD/scid mice induced by injecting an acute promyelocytic leukemia cell line. 査読有り

Ninomiya M, Kiyoi H, Ito M, Hirose Y, Ito M, Naoe T.

Leukemia 18 巻頁： 442 2004年

Normal and oncogenic FLT3. 招待有り査読有り

Naoe T, Kiyoi H.

Cell Mol Life Sci 61 巻頁： 2932 2004年

Different anti-apoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia. 査読有り

Minami Y, Yamamoto K, Kiyoi H, Ueda R, Saito H, Naoe T.

Blood 102 巻頁： 2969 2003年

Comprehensive analysis of gene alterations in acute megakaryoblastic leukemia of Down syndrome. 査読有り

Hirose Y, Kudo K, Kiyoi H, Hayashi Y, Naoe T, Kojima S.

Leukemia 17 巻頁： 2250 2003年

A xeno-transplantable plasma cell leukemia line with a split translocation of the IgH gene. 査読有り

Ohbayashi K, Taniwaki M, Ninomiya M, Kiyoi H, Iida S, Ueda R, Naoe T.

Cancer Genet Cytogen 144 巻頁： 31 2003年

Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy 査読有り

Leukemia 16 巻頁： 203-208 2002年

Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11 査読有り

Leukemia 16 巻頁： 2205-2212 2002年

Selective apoptosis of tandemly duplicated FLT3-transformed leukemia cells by Hsp90 inhibitors 査読有り

Leukemia 16 巻頁： 1535-1540 2002年

Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain 査読有り

Kiyoi H, Ohno R, Ueda R, Saito H, Naoe T.

Oncogene 21 巻頁： 2555-2563 2002年

Rapid screening of leukemia fusion transcripts in acute leukemia by Real-time PCR. 査読有り

Osumi K, Fukui T, Kiyoi H, Kasai M, Kodera Y, Kudo K, Kato K, Matsuyama M, Naito K, Tamimoto M, Hirai H, Saito H, Ohno R, Naoe T.

Leukemia Lymphoma 43 巻頁： 2291 2002年

FLT3 in human hematologic malignancies. 招待有り査読有り

Kiyoi H, Naoe T.

Leukemia Lymphoma 43 巻頁： 1541 2002年

Successful treatment with imatinib mesylate of a CML patient in megakaryoblastic crisis with severe fibrosis. 査読有り

Hirose Y, Kiyoi H, Iwai M, Yokozawa T, Ito M, Naoe T.

Int J Hematol 76 巻頁： 349 2002年

Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations 査読有り

Jpn J Cancer Res 92 巻頁： 638-644 2001年

B-cell precursors differentiated from cord blood CD34+ cells are more immature than those derived from granulocyte colony-stimulating factor-mobilized peripheral blood CD34+ cells 査読有り

Immunology 104 巻頁： 410-417 2001年

FLT3 tyrosine kinase as a target molecule for selective antileukemia therapy 査読有り

Cancer Chemother Pharmacol 48 巻頁： 27-30 2001年

Immunoglobulin variable region structure and B cell malignancies. 査読有り

Kiyoi H, Naoe T.

Int J Hematol 73 巻頁： 47 2001年

Prognostic significance of the cell cycle inhibitor p27Kip1 in acute myeloid leukemia.

Leukemia 14 巻頁： 28-33 2000年

Leukemia relapse reconsidered from the molecular aspect.

Leukemia and Lymphoma 37 巻頁： 527-534 2000年

Histone deacetylase inhibitor but not arsenic trioxide differentiates acute promyelocytic leukaemia cells with t(11;17) in combination with all-trans retinoic acid.

Br J Haematol 108 巻頁： 696-702 2000年

Identification of a novel putative Ran-binding protein and its close homologue

Biochem Biophys Res Commun 278 巻頁： 241-249 2000年

Analysis of genetic polymorphism in NQO1, GST-M1, GST-T1, and CYP3A4 in 469 Japanese patients with therapy-related leukemia/ myelodysplastic syndrome and de novo acute myeloid leukemia. 査読有り

Clin Cancer Res 6 巻頁： 4091-4095 2000年

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. 査読有り

Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H, Naoe T.

Oncogene 19 巻頁： 624-631 2000年

Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia.

Eur J Haematol 65 巻頁： 23-31 2000年

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.

Leukemia 14 巻頁： 374-378 2000年

Poor clinical significance of p53 gene polymorphism in acute myeloid leukemia.

Leuk Res 24 巻頁： 349-352 2000年

Involvement of CD95-independent caspase 8 activation in arsenic trioxide-induced apoptosis. 査読有り

Kitamura K, Minami Y, Yamamoto K, Akao Y, Kiyoi H, Saito H, Naoe T.

Leukemia 14 巻頁： 1743 2000年

Review of the immunoglobulin light chain variable region sequences from multiple myeloma cells.

Leukemia 13 巻頁： 829-830 1999年

Accurate quantitation of residual tumor burden at bone marrow harvest predicts timing of subsequent relapse in patients with common ALL treated by autologous bone marrow transplantation. Nagoya BMT Group.

Bone Marrow Transplant 24 巻頁： 777-784 1999年

Histone deacetylase inhibitors are the potent inducer/enhancer of differentiation in acute myeloid leukemia: a new approach to anti-leukemia therapy.

Leukemia 13 巻頁： 1316-1324 1999年

Molecular evolution of acute myeloid leukaemia in relapse : unstable N-ras and FLT3 genes compared with p53 gene.

Br J Haematol 104 巻頁： 659-664 1999年

Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation.

Leukemia 13 巻頁： 585-589 1999年

Etoposide-realted acute promyelocytic leukemia.

Leukemia 12 巻頁： 1171-1175 1998年

Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia.

Br J Haematol 101 巻頁： 521-528 1998年

Characterization of the immunoglobulin light chain variable region gene expressed in multiple myeloma.

Leukemia 12 巻頁： 601-609 1998年

Prognostic significance of TEL/AML1 fusion transcript in childhood B-precursor acute lymphoblastic leukemia.

J Pediatr Hematolo/oncolo 20 巻頁： 190-195 1998年

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines.

Leukemia 11 巻頁： 1605-1609 1997年

Comparison of the immunoglobulin gene transcripts between immature B lineage acute lymphoblastic leukemia and the normal phenotypic counterparts in the bone marrow.

Leukemia 11 巻頁： 1274-1280 1997年

Unusual feature of the T-cell receptor genes in T-lineage acute lymphoblastic leukemia.

Leuk Res 21 巻頁： 667-674 1997年

New retinoids and arsenic compounds for the treatment of refractory acute promyelocytic leukemia : clinical and basic studies for the next generation.

Cancer Chemotherapy & Pharmacology 40 巻頁： S36-S41 1997年

Internal tandem duplication of FLT3 associated with leukocytosis in acute promyelocytic leukemia.

Leukemia 11 巻頁： 1447-1452 1997年

Mutant AF-2 domain of PML-RARα in retinoic acid-resistant NB4 cells : differentiation induced by RA is triggered directly through PML-RARα and its down-regulation in acute promyelocytic leukemia.

Leukemia 11 巻頁： 1950-1956 1997年

Comparable gene structure of the immunoglobulin heavy chain variable region between multiple myeloma and normal bone marrow lymphocytes.

Leukemia 10 巻頁： 1804-1812 1996年

Different T-cell receptor repertoires between lesions and peripheral blood in acute graft-versus-host disease after allogeneic bone marrow transplantation.

Blood 87 巻頁： 3019-3026 1996年

Comparison of the immunoglobulin heavy-chain complementarity determining region-3 structure among the DNA sequences and the μ-and γ-transcripts in human B-lineage cells.

Immunology 89 巻頁： 324-330 1996年

Comparable profiles of the immunoglobulin heavy chain complementarity determining region(CDR)-3 in CD5₊ and CD5_- human cord blood B lymphocytes.

Immunology 85 巻頁： 236-240 1995年

Detection of minimal residual disease in patients with childhood common acute lymphoblastic leukemia after autologous bone marrow trasplantation with ex vivo purging and systemic IL-2 infusion : unsuccessful prediction of subsequent relapse.

Bone Marrow Transplant 16 巻頁： 437-442 1995年

Continuing immunoglobulin heavy chain gene rearrangements in chronic myeloid leikemia with recurrent B-lymphoid blast crises after bone marrow transplantation.

Leukemia 9 巻頁： 265-270 1995年

Analysis of the joining sequences of the t(15 ; 17)translocation in human acute pronyelocytic leukemia : sequence non-specific recombination between the PML and RARA genes within identical short stretches.

Genes, Chromosomes & Cancer 12 巻頁： 37-44 1995年

Prognostic significance of the RT-PCR assay of PML-RARA trascripts in acute promyelocytic leukemia.

Leukemia 9 巻頁： 588-593 1995年

Characterization of immunoglobulin heavy chain gene rearrangements in chronic myeloid leikemia with recurrent B-lymphoid blast crisis following bone marrow transplantation.

Int Med 33 巻頁： 786-789 1994年

Minimal residual disease status in pre-B acute lymphoblastic leukemia patients after chemotherapy and bone marrow trasplantation : assessment of the antileukemic effects of chemotherapy and BMT.

Leuk Res 17 巻頁： 674-684 1993年

Clonal analysis of multiple point mutations in the N-ras gene in patients with acute myeloid leukemia.

Jap J Cancer Res 84 巻頁： 379-387 1993年

Involvement of the MLL/ALL-1 gene associated with multiple point mutations of the N-ras gene in acute myeloid leukemia with t(11 : 17)(q23 ; q25).

Blood 82 巻頁： 2260-2261 1993年

Effective treatment of adult T cell leukemia/lymphoma with a novel oral antitumor agent, MST-16.

Oncology 49 巻頁： 333-335 1992年

Hermolytic uraemic syndrome during FK506 therapy.

Lancet 340 巻頁： 60-61 1992年

Development of hyperthyroidism in donor and recipient after allogeneic bone marrow transplantation.

Bone Marrow Transplant 10 巻頁： 397-398 1992年

Characterization of the immunoglobulin heavy chain complementarity determining region(CDR)-III sequences from human B cell precursor acute lymphoblastic leukemia cells. 査読有り

J Clin Invest 89 巻頁： 739-746 1992年

Disappearance of minimal residual lymphoblastic leukemia cells 6 months after allogeneic bone marrow transplantation without GVHD. 査読有り

Bone Marrow Transplant 8 巻頁： 59-62 1991年

A case of cALL relapse after allogeneic BMT : recurrence of recipient cell origin, initially determined as being that of donor cell origin by sex chromosome analysis. 査読有り

Br J Haematolo 73 巻頁： 420-422 1989年

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