研究者詳細 - 清井　仁

論文 - 清井　仁

分割表示 324 件中 1 - 20 件目／全件表示 >>

A novel irreversible FLT3 inhibitor, FF-10101, shows excellent efficacy against AML cells with FLT3 mutations. 査読有り

Yamaura T, Nakatani T, Uda K, Ogura H, Shin W, Kurokawa N, Saito K, Fujikawa N, Date T, Takasaki M, Terada D, Hirai A, Akashi A, Chen F, Adachi Y, Ishikawa Y, Hayakawa F, Hagiwara S, Naoe T, Kiyoi H.

Blood 2017年11月

Development and analysis of patient-derived xenograft mouse models in intravascular large B-cell lymphoma. 査読有り

Shimada K, Shimada S, Sugimoto K, Nakatochi M, Suguro M, Hirakawa A, Hocking TD, Takeuchi I, Tokunaga T, Takagi Y, Sakamoto A, Aoki T, Naoe T, Nakamura S, Hayakawa F, Seto M, Tomita A, Kiyoi H.

Leukemia. 30 巻 ( 7 ) 頁： 1568-79 2016年7月

Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. 査読有り

Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.

Nat Genet. 48 巻 ( 5 ) 頁： 569-74 2016年5月

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients. 査読有り

Kihara R, Nagata Y, Kiyoi H, Kato T, Yamamoto E, Suzuki K, Chen F, Asou N, Ohtake S, Miyawaki S, Miyazaki Y, Sakura T, Ozawa Y, Usui N, Kanamori H, Kiguchi T, Imai K, Uike N, Kimura F, Kitamura K, Nakaseko C, Onizuka M, Takeshita A, Ishida F, Suzushima H, Kato Y, Miwa H, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Naoe T.

Leukemia 28 巻頁： 1586-1595 2014年

Leukemic evolution of donor-derived cells harboring IDH2 and DNMT3A mutations after allogeneic stem cell transplantation. 査読有り

Yasuda T, Ueno T, Fukumura K, Yamato A, Ando M, Yamaguchi H, Soda M, Kawazu M, Sai E, Yamashita Y, Murata M, Kiyoi H, Naoe T, Mano H.

Leukemia 28 巻頁： 426-428 2014年

Missense mutations in PML-RARA are critical for the lack of responsiveness to arsenic trioxide treatment. 査読有り

Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.

Blood 118 巻頁： 1600-1609 2011年

KW-2449, a novel multi-kinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation. 査読有り

Shiotsu Y*, Kiyoi H*, Ishikawa Y, Tanizaki R, Shimizu M, Umehara H, Ishii K, Mori Y, Ozeki K, Minami Y, Abe A, Maeda H, Akiyama T, Kanda Y, Sato Y, Akinaga S, Naoe T.

Blood 114 巻頁： 1607-1617 2009年

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies 査読有り

Yamamoto Y, Kiyoi H, Nakano Y, Suzuki R, Kodera Y, Miyawaki S, Asou N, Kuriyama K, Yagasaki F, Shimazaki C, Akiyama H, Saito K, Nishimura M, Motoji T, Shinagawa K, Takeshita A, Saito H, Ueda R, Ohno R, and Naoe T.

Blood 97 巻頁： 2434-2439 2001年

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia. 査読有り

Kiyoi H, Naoe T, Nakano Y, Yokota S, Minami S, Miyawaki S, Asou N, Kuriyama K, Jinnai I, Shimazaki C, Akiyama H, Saito K, Oh H, Motoji T, Omoto E, Saito H, Ohno R, Ueda R.

Blood 93 巻頁： 3074-3080 1999年

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. 査読有り

Kiyoi H, Towatari M, Yokota S, Hamaguchi M, Ohno R, Saito H, Naoe T.

Leukemia 12 巻頁： 1333-1337 1998年

Comparison of clonal architecture between primary and immunodeficient mouse-engrafted acute myeloid leukemia cells 査読有り国際誌

Kawashima Naomi, Ishikawa Yuichi, Kim Jeong Hui, Ushijima Yoko, Akashi Akimi, Yamaguchi Yohei, Hattori Hikaru, Nakashima Marie, Ikeno Seara, Kihara Rika, Nishiyama Takahiro, Morishita Takanobu, Watamoto Koichi, Ozawa Yukiyasu, Kitamura Kunio, Kiyoi Hitoshi

NATURE COMMUNICATIONS 13 巻 ( 1 ) 頁： 1624 2022年3月

Frequent genetic alterations in immune checkpoint-related genes in intravascular large B-cell lymphoma 査読有り国際誌

Shimada Kazuyuki, Yoshida Kenichi, Suzuki Yasuhiro, Iriyama Chisako, Inoue Yoshikage, Sanada Masashi, Kataoka Keisuke, Yuge Masaaki, Takagi Yusuke, Kusumoto Shigeru, Masaki Yasufumi, Ito Takahiko, Inagaki Yuichiro, Okamoto Akinao, Kuwatsuka Yachiyo, Nakatochi Masahiro, Shimada Satoko, Miyoshi Hiroaki, Shiraishi Yuichi, Chiba Kenichi, Tanaka Hiroko, Miyano Satoru, Shiozawa Yusuke, Nannya Yasuhito, Okabe Asako, Kohno Kei, Atsuta Yoshiko, Ohshima Koichi, Nakamura Shigeo, Ogawa Seishi, Tomita Akihiro, Kiyoi Hitoshi

BLOOD 137 巻 ( 11 ) 頁： 1491 - 1502 2021年3月

Allogeneic hematopoietic stem cell transplantation at the first remission for younger adults with<i>FLT3</i>-internal tandem duplication AML: The JALSG AML209-FLT3-SCT study 査読有り国際誌

Kawashima, N; Ishikawa, Y; Atsuta, Y; Sawa, M; Ozawa, Y; Hayashi, M; Kohno, A; Tomita, A; Maeda, T; Sakaida, E; Usuki, K; Hagihara, M; Kanamori, H; Matsuoka, H; Kobayashi, M; Asou, N; Ohtake, S; Matsumura, I; Miyazaki, Y; Naoe, T; Kiyoi, H

CANCER SCIENCE 111 巻 ( 7 ) 頁： 2472 - 2481 2020年7月

Simple and early prediction of severe CAR-T-related adverse events after Axi-cel infusion by initial high fever. 査読有り国際誌

Wakabayashi H, Terakura S, Ishigiwa K, Ohara F, Hirano S, Yokota H, Kuwano S, Furukawa K, Shimada K, Sato T, Hanajiri R, Kiyoi H

International journal of hematology 2025年2月

Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): long-term results of a multicentre, single-arm, phase 2 trial 査読有り国際誌

Shimada, K; Yamaguchi, M; Kuwatsuka, Y; Matsue, K; Sato, K; Kusumoto, S; Nagai, H; Takizawa, J; Fukuhara, N; Nagafuji, K; Miyazaki, K; Ohtsuka, E; Okamoto, A; Sugita, Y; Uchida, T; Kayukawa, S; Wake, A; Ennishi, D; Kondo, Y; Meguro, A; Kin, Y; Minami, Y; Hashimoto, D; Nishiyama, T; Shimada, S; Masaki, Y; Okamoto, M; Atsuta, Y; Kiyoi, H; Suzuki, R; Nakamura, S; Kinoshita, T; Ennishi, D; Kondo, Y; Meguro, A; Kin, Y; Minami, Y; Hashimoto, D; Nishiyama, T; Shimada, S; Masaki, Y; Okamoto, M; Atsuta, Y; Kiyoi, H; Suzuki, R; Nakamura, S; Kinoshita, T

ECLINICALMEDICINE 80 巻頁： 103078 2025年2月

Post-transplant TKIs for Ph+ ALL: practices to date and clinical significance. 査読有り国際誌

Nishiwaki S, Terakura S, Morishita T, Goto T, Inagaki Y, Miyao K, Fukushima N, Hirano D, Tange N, Kurahashi S, Kuwatsuka Y, Kasai M, Iida H, Ozeki K, Sawa M, Nishida T, Kiyoi H

International journal of hematology 2025年1月

Sustained inhibition of CSF1R signaling augments antitumor immunity through inhibiting tumor-associated macrophages 査読有り国際誌

Sato, T; Sugiyama, D; Koseki, J; Kojima, Y; Hattori, S; Sone, K; Nishinakamura, H; Ishikawa, T; Ishikawa, Y; Kato, T; Kiyoi, H; Nishikawa, H

JCI INSIGHT 10 巻 ( 1 ) 2025年1月

Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway 査読有り国際共著国際誌

Adachi, Y; Terakura, S; Osaki, M; Okuno, Y; Sato, Y; Sagou, K; Takeuchi, Y; Yokota, H; Imai, K; Steinberger, P; Leitner, J; Hanajiri, R; Murata, M; Kiyoi, H

NATURE COMMUNICATIONS 15 巻 ( 1 ) 頁： 10376 2024年12月

Nelarabine-combined chemotherapy improves outcome of T-cell acute lymphoblastic leukemia but shows more severe neurotoxicity: JALSG T-ALL213-O 査読有り国際誌

Hayakawa, F; Mori, N; Imai, K; Yokoyama, Y; Katsuoka, Y; Saito, T; Murayama, T; Yamazaki, E; Sato, S; Atsuta, Y; Ishikawa, Y; Sakaida, E; Hatta, Y; Matsumura, I; Miyazaki, Y; Kiyoi, H

CANCER SCIENCE 2024年11月

Clinical characteristics in adolescents and young adults with polycythemia vera and essential thrombocythemia in Japan 査読有り国際誌

Sugimoto, Y; Nagaharu, K; Ohya, E; Ohishi, K; Tawara, I; Ito, T; Gotoh, A; Nakamae, M; Kimura, F; Koike, M; Kirito, K; Wada, H; Usuki, K; Tanaka, T; Mori, T; Wakita, S; Saito, TI; Saito, AM; Shimoda, K; Kurokawa, T; Tomita, A; Edahiro, Y; Hashimoto, Y; Kiyoi, H; Akashi, K; Matsumura, I; Takenaka, K; Komatsu, N

INTERNATIONAL JOURNAL OF HEMATOLOGY 120 巻 ( 6 ) 頁： 684 - 693 2024年10月

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