-
Identification and Characterization of a Novel d-Branched-Chain Amino Acids Importer from Lactobacillus Fermentum.
Reviewed
Aoki K, Mutaguchi Y, Hemmi H, Yoshimura T, Ito T
Chembiochem : a European journal of chemical biology
page：
e202401075
2025.2
-
Effects of producing high levels of hyperthermophile-specific C(25),C(25)-archaeal membrane lipids in Escherichia coli.
Reviewed
Yoshida R, Motoyama K, Ito T, Hemmi H
Biochemical and biophysical research communications
Vol.
729
page：
150349
2024.10
-
Identification of YigL as a PLP/PNP phosphatase in Escherichia coli.
Reviewed
Matsuo H, Yamada N, Hemmi H, Ito T
Applied and environmental microbiology
Vol.
90
(
9
)
page：
e0127024
2024.9
-
Archaeal mevalonate pathway in the uncultured bacterium Candidatus Promineifilum breve belonging to the phylum Chloroflexota.
Reviewed
Kanno K, Kuriki R, Yasuno Y, Shinada T, Ito T, Hemmi H
Applied and environmental microbiology
Vol.
90
(
8
)
page：
e0110624
2024.8
-
A [4Fe-4S] cluster resides at the active center of phosphomevalonate dehydratase, a key enzyme in the archaeal modified mevalonate pathway
Reviewed
Komeyama, M; Kanno, K; Mino, H; Yasuno, Y; Shinada, T; Ito, T; Hemmi, H
FRONTIERS IN MICROBIOLOGY
Vol.
14
page：
1150353
2023.3
-
D-amino acid auxotrophic Escherichia coli strain for in vivo functional cloning of novel D-amino acid synthetic enzyme
Reviewed
Ito Tomokazu, Muto Natsumi, Sakagami Haruna, Tanaka Miho, Hemmi Hisashi, Yoshimura Tohru
FEBS JOURNAL
2023.2
-
Role of the conserved pyridoxal 5'-phosphate-binding protein YggS/PLPBP in vitamin B-6 and amino acid homeostasis
Invited
Reviewed
Ito Tomokazu
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Vol.
86
(
9
)
page：
1183
-
1191
2022.8
-
Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways
Reviewed
International coauthorship
Aoki Mizuki, Vinokur Jeffrey, Motoyama Kento, Ishikawa Rino, Collazo Michael, Cascio Duilio, Sawaya Michael R., Ito Tomokazu, Bowie James U., Hemmi Hisashi
JOURNAL OF BIOLOGICAL CHEMISTRY
Vol.
298
(
7
)
page：
102111
2022.7
-
Identification and biochemical characterization of a heteromeric cis-prenyltransferase from the thermophilic archaeon Archaeoglobus fulgidus
Reviewed
Sompiyachoke Kitty, Nagasaka Arisa, Ito Tomokazu, Hemmi Hisashi
JOURNAL OF BIOCHEMISTRY
Vol.
171
(
6
)
page：
641
-
651
2022.5
-
Identification and characterization of a serine racemase in the silkworm Bombyx mori
Reviewed
Tanaka Yui, Yoshimura Tohru, Hakamata Maho, Saito Chiaki, Sumitani Megumi, Sezutsu Hideki, Hemmi Hisashi, Ito Tomokazu
JOURNAL OF BIOCHEMISTRY
Vol.
172
(
1
)
page：
17
-
28
2022.3
-
Mechanism of Pyridoxine 5 '-Phosphate Accumulation in Pyridoxal 5 '-Phosphate-Binding Protein Deficiency
Reviewed
International coauthorship
Ito Tomokazu, Ogawa Honoka, Hemmi Hisashi, Downs Diana M., Yoshimura Tohru
JOURNAL OF BACTERIOLOGY
Vol.
204
(
3
)
page：
e0052121
2022.3
-
Isopentenyl diphosphate/dimethylallyl diphosphate-specific Nudix hydrolase from the methanogenic archaeon Methanosarcina mazei
Reviewed
Ishibashi Yumi, Matsushima Natsumi, Ito Tomokazu, Hemmi Hisashi
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Vol.
86
(
2
)
page：
246
-
253
2022.1
-
Urinary l-erythro-β-hydroxyasparagine-a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase.
Reviewed
Ito T, Tono M, Kitaura Y, Hemmi H, Yoshimura T
Bioscience reports
Vol.
41
(
4
)
2021.4
-
ビタミンB6・アミノ酸恒常性に関与するピリドキサールリン酸結合タンパク質
Invited
Reviewed
伊藤智和
Vitamins
2021
-
The Role of YggS in Vitamin B6 Homeostasis in Salmonella enterica Is Informed by Heterologous Expression of Yeast <i>SNZ3</i>.
Reviewed
International coauthorship
Vu HN, Ito T, Downs DM
Journal of bacteriology
Vol.
202
(
22
)
2020.10
-
Mechanism of eukaryotic serine racemase-catalyzed serine dehydration
Reviewed
Ito Tomokazu, Matsuoka Mai, Goto Masaru, Watanabe Soichiro, Mizobuchi Taichi, Matsushita Kazuma, Nasu Ryoma, Hemmi Hisashi, Yoshimura Tohru
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
Vol.
1868
(
9
)
page：
140460
2020.9
-
Pyridoxal Reductase, PdxI, Is Critical for Salvage of Pyridoxal in Escherichia coli
Reviewed
International coauthorship
Ito Tomokazu, Downs Diana M.
JOURNAL OF BACTERIOLOGY
Vol.
202
(
12
)
2020.6
-
Inhibition of glycine cleavage system by pyridoxine 5 '-phosphate causes synthetic lethality in glyA yggS and serA yggS in Escherichia coli
Reviewed
International coauthorship
Ito Tomokazu, Hori Ran, Hemmi Hisashi, Downs Diana M., Yoshimura Tohru
MOLECULAR MICROBIOLOGY
Vol.
113
(
1
)
page：
270
-
284
2020.1
-
Conserved Pyridoxal 5 '-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5 '-Phosphate in Escherichia coli
Reviewed
International coauthorship
Ito Tomokazu, Yamamoto Kana, Hori Ran, Yamauchi Ayako, Downs Diana M., Hemmi Hisashi, Yoshimura Tohru
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Vol.
85
(
11
)
2019.6
-
Conserved Pyridoxal 5'-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5'-Phosphate in Escherichia coli.
Reviewed
International coauthorship
Ito T, Yamamoto K, Hori R, Yamauchi A, Downs DM, Hemmi H, Yoshimura T
Appl Environ Microbiol.
Vol.
85
(
11
)
2019.5
-
Urinary D-serine level as a predictive biomarker for deterioration of renal function in patients with atherosclerotic risk factors
Reviewed
Iwakawa Hidehiro, Makabe Shin, Ito Tomokazu, Yoshimura Tohru, Watanabe Hiroyuki
BIOMARKERS
Vol.
24
(
2
)
page：
159-165
2019.2
-
Inhibition of glycine cleavage system by pyridoxine 5'-phosphate causes synthetic lethality in glyA yggS and serA yggS in Escherichia coli
Reviewed
International coauthorship
Ito T,Hori R,Hemmi H, Downs DM, Yoshimura T
Molecular Microbiology
page：
in press
2019
-
Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate
Reviewed
Hayakawa Hajime, Motoyama Kento, Sobue Fumiaki, Ito Tomokazu, Kawaide Hiroshi, Yoshimura Tohru, Hemmi Hisashi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Vol.
115
(
40
)
page：
10034-10039
2018.10
-
D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum
Reviewed
Ito Tomokazu, Hamauchi Natsuki, Hagi Taisuke, Morohashi Naoya, Hemmi Hisashi, Sato Yukie G., Saito Tamao, Yoshimura Tohru
FRONTIERS IN MICROBIOLOGY
Vol.
9
page：
784
2018.4
-
Production of Ophthalmic Acid Using Engineered Escherichia coli.
Reviewed
Ito T, Tokoro M, Hori R, Hemmi H, Yoshimura T
Applied and environmental microbiology
Vol.
84
(
7
)
2018.4
-
Utilization of an intermediate of the methylerythritol phosphate pathway, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate, as the prenyl donor substrate for various prenyltransferases.
Hayashi Y, Ito T, Yoshimura T, Hemmi H
Bioscience, biotechnology, and biochemistry
Vol.
82
(
6
)
page：
993
-
1002
2018
-
Occurrence of the (2R,3S) -Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus
Reviewed
Ito Tomokazu, Yu Zhuoer, Yoshino Issei, Hirozawa Yurina, Yamamoto Kana, Shinoda Kiyotugu, Watanabe Akira, Hemmi Hisashi, Asada Yasuhiko, Yoshimura Tohru
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Vol.
65
(
30
)
page：
6131-6139
2017.8
-
Development of a versatile method for targeted gene deletion and insertion by using the pyrF gene in the psychrotrophic bacterium, Shewanella livingstonensis Ac10
Reviewed
Ito T., Gong C., Kawamoto J., Kurihara T.
Journal of Bioscience and Bioengineering.
page：
doi:10.1016/j.jbiosc.2016.06.004
2016
-
mTORC1 is involved in the regulation of BCAA catabolism in mouse heart
Reviewed
Zhen H., Kitaura Y., Kadota Y., Ishikawa T., Kondo Y., Xu M., Morishita Y., Ota M., Ito T., Shimomura Y
FEBS Open Bio.
(
6
)
page：
43-49
2016
-
Serine racemase is involved in D-aspartate biosynthesis.
Reviewed
Ito T., Hayashida M., Kobayashi S., Muto N., Hayashi A., Yoshimura T., Mori H.
Journal of Biochemistry
page：
160,345-353
2016
-
Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5' phosphate-binding protein YggS
Reviewed
Ito T., Yamauchi A., Hemmi H., Yoshimura T.
Journal of Bioscience and Bioengineering
Vol.
122
page：
689-693
2016
-
Is D-aspartate produced by glutamic-oxaloacetic transaminase-1 like 1 (Got1l1), a putative aspartate racemase?
Reviewed
Tanaka-Hayashi A., Hayashi S., Inoue R., Ito T., Kouno K., Yoshida T., Watanabe M., Yoshimura T., Mori H
(
47
)
page：
79-85
2015
-
Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Reviewed
Okuda K., Kato S., Ito T., Shiraki S., Kawase Y., Goto M., Kawashima S., Hemmi H., Fukada H., Yoshimura T
Molecular Microbiology
page：
245-257
2015
-
PEGylated D-Serine Dehydratase as a D-Serine Reucing Agent
Reviewed
Ito T., Takada H., Isobe K., Suzuki M., Kitaura Y., Hemmi H., Matsuda T., Sasabe J., Yoshimura T
Journal of Parmacetuical and Biomedical Analysis
2015
-
Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator
Reviewed
Journal of Biochemistry
page：
pii: mvv040
2015
-
A New Member of MocR/GabR-type PLP-Binding Regulator of D-Alanyl-D-Alanine Ligase in Brevibacillus brevis
Reviewed
Takenaka T., Ito T., Miyahara I., Hemmi H., Yoshimura T
FEBS J
2015
-
Reaction mechanism of Zn2+-dependent D-serine dehydratase
Reviewed
Tomokazu Ito, Mai Matsuoka, Kazushi Koga, Hisashi Hemmi, and Tohru Yoshimura
The Journal of Biochemistry
page：
--
2014
-
Reaction mechanism of yeast D-serine dehydratase
Vitamins
Vol.
88
(
11
)
page：
576-579
2014
-
Reaction mechanism of eukaryotic serine racemase
Vitamins
Vol.
88
(
8
)
page：
425-428
2014
-
Vitami B6-dependet enzymes involved in D-serine metabolism: serine racemase and D-serine dehydratase
Vitamins
Vol.
88
(
9
)
page：
462-468
2014
-
A Conserved Pyridoxal Protein that Regulates Ile and Val Metabolism.
Reviewed
Ito T, Iimori J, Takayama S, Moriyama A, Yamauchi A, Hemmi H, Yoshimura T
Journal of Bacteriology
2013
-
Metal ion dependency of serine racemase from Dictyostelium discoideum
Reviewed
Ito T, Murase H, Maekawa M, Goto M, Hayashi S, Saito H, Maki M, Hemmi H, Yoshimura T.
Amino Acids
2012
-
A highly sensitive enzymatic assay for D- and total serine detection using D-serine dehydratase from Saccharomyces cerevisiae
Reviewed
Naka T, Ito T, Hemmi H, Yoshimura T
J. Mol. Catal. B Enzym.
Vol.
67
page：
150-154
2011
-
哺乳類のアスパラギン酸ラセマーゼ
伊藤智和、吉村徹
Vol.
85
page：
661-662
2011
-
右手型アミノ酸の役割
伊藤智和
生物工学会誌
Vol.
88
page：
613
2010
-
The implication of YggT of Escherichia coli in osmotic regulation
Ito T, Uozumi N, Nakamura T, Takayama S, Matsuda N, Aiba H, Hemmi H, Yoshimura T
Biosci. Biotechnol. Biochem.
Vol.
73
page：
2698-2704
2009
-
A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae
Reviewed
Ito T, Hemmi H, Kataoka K, Mukai Y, Yoshimura T
Biochem J.
Vol.
409
page：
399-406
2008
-
Saccharomyces cerevisiaeの新奇D-セリンデヒドラターゼとD-セリン定量への応用
伊藤智和,吉村徹
Vol.
82
page：
349-351
2008
-
Enzymatic assay of D-serine using D-serine dehydratase from Saccharomyces cerevisiae
Reviewed
Ito T, Takahashi K, Naka T, Hemmi H, Yoshimura T
Anal Biochem.
Vol.
371
page：
167-172
2007
