Updated on 2024/03/30

写真a

 
UENOYAMA Yoshihisa
 
Organization
Graduate School of Bioagricultural Sciences Department of Animal Sciences Associate professor
Graduate School
Graduate School of Bioagricultural Sciences
Undergraduate School
School of Agricultural Sciences Department of Bioresource Sciences
Title
Associate professor
Contact information
メールアドレス

Degree 1

  1. 博士 (農学) ( 1999.3   岡山大学 ) 

Research Interests 2

  1. Neuroendocrinology

  2. Reproductive Science

Research Areas 2

  1. Others / Others  / Basic Veterinary Science/Basic Animal Science

  2. Others / Others  / Applied Animal Science

Current Research Project and SDGs 3

  1. 家畜の効率的な繁殖技術の開発

  2. 性成熟のタイミング制御する脳内メカニズムの解明

  3. 新規GPCRリガンドによる生殖機能調節に関する研究

Research History 5

  1. Nagoya University   Associate professor

    2015.4

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    Country:Japan

  2. Nagoya University   Assistant Professor

    2007.4 - 2015.3

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    Country:Japan

  3. Nagoya University   Assistant

    2000.4 - 2007.3

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    Country:Japan

  4. Okayama University

    1999.4 - 2000.3

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    Country:Japan

  5. 日本学術振興会特別研究員 DC2 岡山大学

    1998.4 - 1999.3

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    Country:Japan

Education 1

  1. Okayama University   Graduate School, Division of National Science and Technology

    - 1999.3

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    Country: Japan

Professional Memberships 15

  1. 日本繁殖生物学会

    1994

  2. Japanese Society of Animal Reproduction

    2009.4 - 2012.3

  3. 日本繁殖生物学会   広報理事

    2019.9 - 2023.9

  4. 日本繁殖生物学会   プログラム委員

    2019.9

  5. 日本繁殖生物学会   編集委員

    2019.9

  6. 日本内分泌学会   評議員

    2024.4

  7. 日本内分泌学会   編集委員

    2021.7

  8. 日本生殖内分泌学会   評議員

    2021.5

  9. 日本神経内分泌学会   評議員

    2016

  10. 日本下垂体研究会   評議員

    2015.8

  11. 日本比較内分泌学会   幹事

    2023.11

  12. Society for Study of Reproduction

  13. Endocrine Society

  14. Society for Neuroscience

  15. Japanese Society of Animal Science

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Awards 1

  1. 学術賞

    2017.9   日本繁殖生物学会   ほ乳類の繁殖機能制御機構におけるキスペプチンの役割に関する研究

    上野山賀久

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

 

Papers 120

  1. Conditional Oprk1-dependent Kiss1 deletion in kisspeptin neurons caused estrogen-dependent LH pulse disruption and LH surge attenuation in female rats Reviewed

    Nagae M, Yamada K, Enomoto Y, Kometani M, Tsuchida H, Panthee A, Nonogaki M, Matsunaga N, Takizawa M, Matsuzaki S, Hirabayashi M, Inoue N, Tsukamura H, Uenoyama Y

    Scientific Reports   Vol. 13 ( 1 )   2024.11

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-023-47222-5

  2. Neonatal aromatase inhibition blocked defeminization of AVPV Kiss1 neurons and LH surge-generating system in male rats Reviewed

    Yamada K, Mano T, Hazim S, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H

    Endocrinology   Vol. 165 ( 4 )   2024.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/endocr/bqae028

  3. Capturing temperature changes on the ocular surface along with estrus and ovulation using infrared thermography in Japanese Black cows Reviewed

    Ozaki R, Inoue S, Yorozui Y, Ichikawa R, Yamada N, Higashi S, Matsuyama S, Tsukamura H, Ohkura S, Uenoyama Y, Morita Y

    J Reprod Dev   Vol. 70 ( 1 ) page: 49 - 54   2023.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2022-116

  4. Sex difference in developmental changes in visualized Kiss1 neurons in newly generated Kiss1-Cre rats Reviewed

    Yamada K, Nagae M, Mano T, Tsuchida H, Hazim S, Goto T, Sanbo M, Hirabayashi M, Inoue N, Uenoyama Y, Tsukamura H

    J Reprod Dev   Vol. 69 ( 5 ) page: 227 - 238   2023.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2023-019

  5. Enkephalin-δ opioid receptor signaling partly mediates suppression of LH release during early lactation in rats Reviewed

    Tsuchida H, Takizawa M, Nonogaki M, Inoue N, Uenoyama Y, Tsukamura H

    J Reprod Dev   Vol. 69 ( 4 )   2023.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2023-006

  6. Kisspeptin and lactational anestrus: Current understanding and future prospects Invited Reviewed

    Uenoyama Y, Inoue N, Tsukamura H

    Peptides   Vol. 166   2023.5

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.peptides.2023.171026

  7. KNDy neurones and GnRH/LH pulse generation: Current understanding and future aspects Invited Reviewed

    Uenoyama Y, Tsukamura H

    J Neuroendocrinol   Vol. 35   2023.5

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: 10.1111/jne.13285

  8. Hindbrain Adenosine 5-Triphosphate (ATP)-Purinergic Signaling Triggers LH Surge and Ovulation via Activation of AVPV Kisspeptin Neurons in Rats. Reviewed

    Inoue N, Hazim S, Tsuchida H, Dohi Y, Ishigaki R, Takahashi A, Otsuka Y, Yamada K, Uenoyama Y, Tsukamura H

    The Journal of neuroscience   Vol. 43 ( 12 ) page: 2140 - 2152   2023.3

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    Language:English  

    DOI: 10.1523/JNEUROSCI.1496-22.2023

  9. Enkephalin-δ Opioid Receptor Signaling Mediates Glucoprivic Suppression of LH Pulse and Gluconeogenesis in Female Rats. Reviewed

    Tsuchida H, Nonogaki M, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H

    Endocrinology   Vol. 164 ( 3 )   2023.1

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    Language:English  

    DOI: 10.1210/endocr/bqac216

  10. Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model Invited Reviewed

    Shima Yuichi, Miyabayashi Kanako, Mori Takami, Ono Koji, Kajimoto Mizuki, Cho Hae Lim, Tsuchida Hitomi, Uenoyama Yoshihisa, Tsukamura Hiroko, Suzuki Kentaro, Choi Man Ho, Toida Kazunori

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Vol. 24 ( 1 )   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms24010192

  11. Dynorphin-Kappa-opioid receptor signaling, but not mu-opioid receptor signaling, partly mediates the suppression of luteinizing hormone release during late lactation in rats Invited Reviewed

    Tsuchida Hitomi, Nonogaki Miku, Inoue Naoko, Uenoyama Yoshihisa, Tsukamura Hiroko

    Neuroscience letters   Vol. 791   page: 136920   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2022.136920

  12. Establishment of embryo transfer in the musk shrew (Suncus murinus). Reviewed

    Inoue N, Hotta A, Goto T, Hirabayashi M, Uenoyama Y, Tsukamura H

    The Journal of reproduction and development   Vol. 66 ( 5 ) page: 340 - 344   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2022-003

  13. Opioidergic pathways and kisspeptin in the regulation of female reproduction in mammals Invited Reviewed

    Uenoyama Y, Tsuchida H, Nagae M, Inoue N, Tsukamura H

    Front Neurosci   Vol. 16   page: 958377   2022.9

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    Authorship:Lead author   Language:English  

    DOI: https://doi.org/10.3389/fnins.2022.958377

  14. A Survey of Genome-Wide Genetic Characterizations of Crossbred Dairy Cattle in Local Farms in Cambodia Invited Reviewed International coauthorship

    Somony Mam, Bengthay Tep, Soriya Rin, Yoshihisa Uenoyama, Shuichi Matsuyama, Satoshi Ohkura, Tetsuma Murase, Mitsuo Nunome, Yasuhiro Morita

    Animals   Vol. 12 ( 16 ) page: 2072   2022.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani12162072

  15. Central somatostatin-somatostatin receptor 2 signaling mediates lactational suppression of luteinizing hormone release via the inhibition of glutamatergic interneurons during late lactation in rats Reviewed

    Sugimoto A, Tsuchida H, Nagae M, Inoue N, Uenoyama Y, Tsukamura H

    J Reprod Dev   Vol. 68 ( 3 ) page: 190 - 197   2022.6

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    Language:English  

    DOI: https://doi.org/10.1262/jrd.2022-009

  16. Generation of Tfap2c-T2A-tdTomato knock-in reporter rats via adeno-associated virus-mediated efficient gene targeting Reviewed

    Oikawa M, Nagae M, Mizuno N, Iwatsuki K, Yoshida F, Inoue N, Uenoyama Y, Tsukamura H, Nakauchi H, Hirabayashi M, Kobayashi T

    Mol Reprod Dev   Vol. 89   page: 129–132   2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

  17. Kiss1-dependent and independent release of luteinizing hormone and testosterone in perinatal male rats Reviewed

    Chen J, Minabe S, Munetomo A, Magata F, Sato M, Nakamura S, Hirabayashi M, Ishihara Y, Yamazaki T, Uenoyama Y, Tsukamura H, Matsuda F

    Endocrine Journal     2022.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1507/endocrj.EJ21-0620

  18. Cellular and molecular mechanisms regulating the KNDy neuronal activities to generate and modulate GnRH pulse in mammals Reviewed

    Ikegami K, Watanabe Y, Nakamura S, Goto T, Inoue N, Uenoyama Y, Tsukamura H

    Front Neuroendocrinol   Vol. 64   page: 100968   2021.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.yfrne.2021.100968

  19. Kisspeptin neurons as a key player bridging the endocrine system and sexual behavior in mammals Reviewed

    Nakamura S, Watanabe Y, Goto T, Ikegami K, Inoue N, Uenoyama Y, Tsukamura H

    Front Neuroendocrinol   Vol. 64   page: 100952   2021.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.yfrne.2021.100952

  20. Role of KNDy neurons expressing kisspeptin, neurokinin B, and dynorphin A as a GnRH pulse generator controlling mammalian reproduction Reviewed

    Uenoyama Y, Nagae M, Tsuchida H, Inoue N, Tsukamura H

    Front Endocrinol (Lausanne)   Vol. 12   page: 724632   2021.9

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fendo.2021.724632

  21. Kisspeptin neurons and estrogen-estrogen receptor α signaling: Unraveling the mystery of steroid feedback system regulating mammalian reproduction Reviewed

    Uenoyama Y, Inoue N, Nakamura S, Tsukamura H

    Int J Mol Sci   Vol. 22   page: 9229   2021.9

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms22179229

  22. Central μ-opioid receptor antagonism blocks glucoprivic LH pulse suppression and gluconeogenesis/feeding in female rats Reviewed

    Tsuchida H, Kawai N, Yamada K, Takizawa M, Inoue N, Uenoyama Y, Tsukamura H

    Endocrinology   Vol. 162   page: bqab140   2021.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/endocr/bqab140

  23. Morphological Analysis of the Hindbrain Glucose Sensor-Hypothalamic Neural Pathway Activated by Hindbrain Glucoprivation Reviewed

    Sato M, Minabe S, Sakono T, Magata F, Nakamura S, Watanabe Y, Inoue N, Uenoyama Y, Tsukamura H, Matsuda F

    Endocrinology   Vol. 162   page: bqab125   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/endocr/bqab125

  24. Reduction of arcuate kappa-opioid receptor-expressing cells increased luteinizing hormone pulse frequency in female rats Reviewed

    Dai M, Nakamura S, Takahashi C, Sato M, Munetomo A, Magata F, Uenoyama Y, Tsukamura H, Matsuda F

    Endocr J     2021.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1507/endocrj.EJ20-0832

  25. Direct evidence that KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator. Reviewed

    Nagae M, Uenoyama Y, Okamoto S, Tsuchida H, Ikegami K, Goto T, Majarune S, Nakamura S, Sanbo M, Hirabayashi M, Kobayashi K, Inoue N, Tsukamura H

    Proceedings of the National Academy of Sciences of the United States of America   Vol. 118 ( 5 ) page: e2009156118   2021.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.2009156118

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  26. Paraventricular Dynorphin A Neurons Mediate LH Pulse Suppression Induced by Hindbrain Glucoprivation in Female Rats. Reviewed

    Tsuchida H, Mostari P, Yamada K, Miyazaki S, Enomoto Y, Inoue N, Uenoyama Y, Tsukamura H

    Endocrinology   Vol. 161 ( 11 )   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/endocr/bqaa161

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  27. Facilitatory and inhibitory role of central amylin administration in the regulation of the gonadotropin-releasing hormone pulse generator activity in goats Reviewed

    Kitagawa Y, Sasaki T, Suzumura R, Morishima A, Tatebayashi R, Assadullah, Ieda N, Morita Y, Matsuyama S, Inoue N, Uenoyama Y, Tsukamura H, Ohkura S

    Neuroscience Letters   Vol. 736   page: 135276   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2020.135276

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  28. Mating-induced increase in Kiss1 mRNA expression in the anteroventral periventricular nucleus prior to an increase in LH and testosterone release in male rats. Reviewed

    Watanabe Y, Ikegami K, Nakamura S, Uenoyama Y, Ozawa H, Maeda KI, Tsukamura H, Inoue N

    The Journal of Reproduction and Development   Vol. 66   page: 579 - 586   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2020-067

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  29. Testosterone Supplementation Rescues Spermatogenesis and In Vitro Fertilizing Ability of Sperm in Kiss1 Knockout Mice Reviewed

    Goto T, Hirabayashi M, Watanabe Y, Sanbo M, Tomita K, Inoue N, Tsukamura H, Uenoyama Y

    Endocrinology   Vol. 161 ( 9 ) page: bqaa092   2020.9

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/endocr/bqaa092

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  30. Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice. Reviewed

    Ikegami K, Goto T, Nakamura S, Watanabe Y, Sugimoto A, Majarune S, Horihata K, Nagae M, Tomikawa J, Imamura T, Sanbo M, Hirabayashi M, Inoue N, Maeda KI, Tsukamura H, Uenoyama Y

    The Journal of Reproduction and Development   Vol. 66 ( 4 ) page: 359 - 367   2020.8

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2020-026

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  31. Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats. Reviewed

    Sasaki T, Sonoda T, Tatebayashi R, Kitagawa Y, Oishi S, Yamamoto K, Fujii N, Inoue N, Uenoyama Y, Tsukamura H, Maeda KI, Matsuda F, Morita Y, Matsuyama S, Ohkura S

    The Journal of Reproduction and Development   Vol. 66 ( 4 ) page: 351 - 357   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2019-145

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  32. Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice. Reviewed

    Minabe S, Nakamura S, Fukushima E, Sato M, Ikegami K, Goto T, Sanbo M, Hirabayashi M, Tomikawa J, Imamura T, Inoue N, Uenoyama Y, Tsukamura H, Maeda KI, Matsuda F

    The Journal of Reproduction and Development   Vol. 66 ( 4 ) page: 369 - 375   2020.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2019-164

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  33. Establishment of immortalised cell lines derived from female Shiba goat KNDy and GnRH neurones Reviewed

    Suetomi Y, Tatebayashi R, Sonoda S, Munetomo A, Matsuyama S, Inoue N, Uenoyama Y, Takeuchi Y, Tsukamura H, Ohkura S, Matsuda F

    Journal of Neuroendocrinology   Vol. 32 ( 6 ) page: e12857   2020.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jne.12857

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  34. GnRH(1-5), a metabolite of gonadotropin-releasing hormone, enhances luteinizing hormone release via activation of kisspeptin neurons in female rats Reviewed

    Ieda N, Assadullah, Minabe S, Ikegami K, Watanabe Y, Sugimoto Y, Sugimoto A, Kawai N, Ishii H, Inoue N, Uenoyama Y, Tsukamura H

    Endocrine Journal   Vol. 67 ( 4 ) page: 409 - 418   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1507/endocrj.EJ19-0444

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  35. Seasonal changes in the reproductive performance in local cows receiving artificial insemination in the Pursat province of Cambodia. Reviewed International coauthorship

    Tep B, Morita Y, Matsuyama S, Ohkura S, Inoue N, Tsukamura H, Uenoyama Y, Pheng V

    Asian-Australasian Journal of Animal Sciences     2020.4

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.5713/ajas.19.0893

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  36. Retinoblastoma binding protein 7 is involved in Kiss1 mRNA upregulation in rodents. Reviewed

    Horihata K, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H

    The Journal of Reproduction and Development   Vol. 66 ( 2 ) page: 125 - 133   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2019-149

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  37. Role of kisspeptin neurons as a GnRH surge generator: Comparative aspects in rodents and non-rodent mammals Reviewed

    Matsuda F, Ohkura S, Magata F, Munetomo A, Chen J, Sato M, Inoue N, Uenoyama Y, Tsukamura H

    Journal Of Obstetrics And Gynaecology Research   Vol. 45 ( 12 ) page: 2318 - 2329   2019.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/jog.14124

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  38. Ad libitum feeding triggers puberty onset associated with increases in arcuate Kiss1 and Pdyn expression in growth-retarded rats. Reviewed

    Majarune S, Nima P, Sugimoto A, Nagae M, Inoue N, Tsukamura H, Uenoyama Y

    The Journal of reproduction and development   Vol. 65 ( 5 ) page: 397-406   2019.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2019-048

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  39. Peripheral administration of kappa-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats

    Sasaki T., Ito D., Sonoda T., Morita Y., Wakabayashi Y., Yamamura T., Okamura H., Oishi S., Noguchi T., Fujii N., Uenoyama Y., Tsukamura H., Maeda K. I, Matsuda F., Ohkura S.

    DOMESTIC ANIMAL ENDOCRINOLOGY   Vol. 68   page: 83-91   2019.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.domaniend.2018.12.011

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  40. Central Mechanism Controlling Pubertal Onset in Mammals: A Triggering Role of Kisspeptin

    Uenoyama Y, Inoue N, Nakamura S, Tsukamura H

    FRONTIERS IN ENDOCRINOLOGY   Vol. 10   page: 312   2019.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fendo.2019.00312

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  41. Neonatal Estrogen Causes Irreversible Male Infertility via Specific Suppressive Action on Hypothalamic Kiss1 Neurons

    Minabe Shiori, Sato Marimo, Inoue Naoko, Watanabe Youki, Magata Fumie, Matsuda Fuko, Uenoyama Yoshihisa, Ozawa Hitoshi, Tsukamura Hiroko

    ENDOCRINOLOGY   Vol. 160 ( 5 ) page: 1223-1233   2019.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/en.2018-00732

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  42. Morphological analysis for neuronal pathway from the hindbrain ependymocytes to the hypothalamic kisspeptin neurons.

    Deura C, Minabe S, Ikegami K, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H

    The Journal of reproduction and development   Vol. 65 ( 2 ) page: 129-137   2019.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2018-122

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  43. Study on the Reproductive Performance and Problems in Crossbred Cows in Jalalabad, East of Afghanistan Invited Reviewed

    Assadullah, Ieda N, Bayer DM, Stanikzai PM, Memlawal R, Inoue N, Uenoyama Y, Tsukamura H

    J Intl Cooper Agric Dev   Vol. 17   page: 2 - 7   2019

  44. Kisspeptin: A Central Regulator of Reproduction in Mammals Invited Reviewed

    Ieda N, Hassaneen ASA, Inoue N, Uenoyama Y, Tsukamura H

    SVU- International Journal of Veterinary Sciences   Vol. 3. ( 1 ) page: 10 - 26   2019

  45. The roles of kisspeptin in the mechanism underlying reproductive functions in mammals.

    Uenoyama Y, Inoue N, Maeda KI, Tsukamura H

    The Journal of reproduction and development     2018.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1262/jrd.2018-110

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  46. Co-expression of the calcitonin receptor gene in the hypothalamic kisspeptin neurons in female rats.

    Assadullah, Ieda N, Kawai N, Ishii H, Ihara K, Inoue N, Uenoyama Y, Tsukamura H

    Reproductive medicine and biology   Vol. 17 ( 2 ) page: 164-172   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/rmb2.12085

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  47. Somatostatin-Somatostatin Receptor 2 Signaling Mediates LH Pulse Suppression in Lactating Rats

    Sugimoto A, Tsuchida H, Ieda N, Ikegami K, Inoue N, Uenoyama Y, Tsukamura H

    ENDOCRINOLOGY   Vol. 160 ( 2 ) page: 473 - 483   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/en.2018-00882

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  48. SB223412, a neurokinin-3 receptor-selective antagonist, suppresses testosterone secretion in male guinea pigs

    Nakamura Sho, Ito Yoshiko, Yamamoto Koki, Takahashi Chudai, Dai Mingdao, Tanahashi Miyu, Uenoyama Yoshihisa, Tsukamura Hiroko, Oishi Shinya, Maeda Kei-ichiro, Matsuda Fuko

    THERIOGENOLOGY   Vol. 102   page: 183-189   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.theriogenology.2017.07.053

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  49. Long-Term Neonatal Estrogen Exposure Causes Irreversible Inhibition of LH Pulses by Suppressing Arcuate Kisspeptin Expression via Estrogen Receptors alpha and beta in Female Rodents

    Minabe Shiori, Ieda Nahoko, Watanabe Youki, Inoue Naoko, Uenoyama Yoshihisa, Maeda Kei-ichiro, Tsukamura Hiroko

    ENDOCRINOLOGY   Vol. 158 ( 9 ) page: 2918-2929   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1210/en.2016-1144

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  50. Evolutionally Conserved Function of Kisspeptin Neuronal System Is Nonreproductive Regulation as Revealed by Nonmammalian Study

    Nakajo Mikoto, Kanda Shinji, Karigo Tomomi, Takahashi Akiko, Akazome Yasuhisa, Uenoyama Yoshihisa, Kobayashi Makito, Oka Yoshitaka

    ENDOCRINOLOGY   Vol. 159 ( 1 ) page: 163-183   2017

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    DOI: 10.1210/en.2017-00808

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  51. Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones

    Ikegami K., Minabe S., Ieda N., Goto T., Sugimoto A., Nakamura S., Inoue N., Oishi S., Maturana A. D., Sanbo M., Hirabayashi M., Maeda K-I, Tsukamura H., Uenoyama Y.

    JOURNAL OF NEUROENDOCRINOLOGY   Vol. 29 ( 6 )   2017

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    DOI: 10.1111/jne.12480

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  52. Evaluation of heat stress response in crossbred dairy cows under tropical climate by analysis of heart rate variability

    Bun Chan, Watanabe Youki, Uenoyama Yoshihisa, Inoue Naoko, Ieda Nahoko, Matsuda Fuko, Tsukamura Hiroko, Kuwahara Masayoshi, Maeda Kei-ichiro, Ohkura Satoshi, Pheng Vutha

    JOURNAL OF VETERINARY MEDICAL SCIENCE   Vol. 80 ( 1 ) page: 181-185   2017

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    DOI: 10.1292/jvms.17-0368

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  53. Enhancement of the luteinising hormone surge by male olfactory signals is associated with anteroventral periventricular Kiss1 cell activation in female rats

    Watanabe Y, Ikegami K, Ishigaki R, Ieda N, Uenoyama Y, Maeda KI, Tsukamura H, Inoue N

    JOURNAL OF NEUROENDOCRINOLOGY   Vol. 29 ( 8 )   2017

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    DOI: 10.1111/jne.12505

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  54. CRISPR/Cas9-mediated genome editing in wild-derived mice: generation of tamed wild-derived strains by mutation of the a (nonagouti) gene

    Hirose M, Hasegawa A, Mochida K, Matoba S, Hatanaka Y, Inoue K, Goto T, Kaneda H, Yamada I, Furuse T, Abe K, Uenoyama Y, Tsukamura H, Wakana S, Honda A, Ogura A

    SCIENTIFIC REPORTS   Vol. 7   page: 42476   2017

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    DOI: 10.1038/srep42476

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  55. Characterization of smallholder livestock farming in Kampong Cham province, Cambodia -A pilot study in Prey Chhor district-. Invited Reviewed

    Ieda N, Watanabe Y, Bun C, Pheng V, Uenoyama Y

    J Intl Cooper Agric Dev   Vol. 15   page: 42 - 47   2017

  56. Neonatal kisspeptin is steroid-independently required for defeminisation and peripubertal kisspeptin-induced testosterone is required for masculinisation of the brain Reviewed

    Nakamura S, Uenoyama Y, Ikegami K, Dai M, Watanabe Y, Takahashi C, Hirabayashi M, Tsukamura H, Maeda KI.

    J Neuroendocrinol     page: 10.1111/jne.12409   2016

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    DOI: 10.1111/jne.12409

  57. Immunohistochemical characterization of the arcuate kisspeptin/neurokinin B/dynorphin (KNDy) and preoptic kisspeptin neuronal populations in the hypothalamus during the estrous cycle in heifers Reviewed

    Hassaneen ASA, Naniwa Y, Suetomi Y, Matsuyama S, Kimura K, Ieda N, Inoue N, Uenoyama Y, Tsukamura H, Maeda K-I, Matsuda F, Ohkura S

    J Reprod Dev   Vol. 62   page: 471-477   2016

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  58. The roles of kisspeptin revisited: inside and outside the hypothalamus Invited Reviewed

    Uenoyama Y, Pheng V, Tsukamura H, Maeda K.

    J Reprod Dev   Vol. 62   page: 537-545   2016

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  59. Molecular and epigenetic mechanism regulating hypothalamic Kiss1 gene expression in mammals Invited Reviewed

    Uenoyama Y, Tomikawa J, Inoue N, Goto T, Minabe S, Ieda N, Nakamura S, Watanabe Y, Ikegami K, Matsuda F, Ohkura S, Maeda KI, Tsukamura H

    Neuroendocrinology   Vol. 103   page: 640 - 649   2016

  60. Pharmacological and morphological evidence of AMPK-mediated energy sensing in the lower brain stem ependymocytes to control reproduction in female rodents Reviewed

    Minabe S, Deura C, Ikegami K, Goto T, Sanbo M, Hirabayashi M, Inoue N, Uenoyama Y, Maeda KI, Tsukamura H

    Endocrinology   Vol. 156   page: 2278-2287   2015.6

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  61. The LH surge-generating system is functional in male goats as in females: involvement of kisspeptin neurones in the medial preoptic area

    Matsuda, F., Nakatsukasa, K., Suetomi, Y., Naniwa, Y., Ito, D., Inoue, N., Wakabayashi, Y., Okamura, H., Maeda, K.I., Uenoyama, Y., Tsukamura, H. and Ohkura, S.

    J. Neuroendocrinol.   Vol. 27   page: 57-65   2015

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  62. Identification of hypothalamic arcuate nucleus-specific enhancer region of Kiss1 gene in mice Reviewed

    Goto, T., Tomikawa, J., Ikegami, K., Minabe, S., Abe, H., Fukanuma, T., Imamura, T., Takase, K., Sanbo, M., Tomita, K., Hirabayashi, M., Maeda, K.I., Tsukamura, H. and Uenoyama, Y.

    Mol. Endocrinol.   Vol. 29   page: 121-129   2015

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  63. Lack of pulse and surge modes and glutamatergic stimulation of LH release in Kiss1 knockout rats. Reviewed

    Uenoyama Y, Nakamura S, Hayakawa Y, Ikegami K, Watanabe Y, Deura C, Minabe S, Tomikawa J, Goto T, Ieda N, Inoue N, Sanbo M, Tamura C, Hirabayashi M, Maeda KI, Tsukamura H

    J. Neuroendocrinol.   Vol. 27   page: 187 - 197   2015

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  64. Central estrogen action sites involved in prepubertal restraint of pulsatile luteinizing hormone release in female rats Reviewed

    Uenoyama Y, Tanaka A, Takase K, Yamada S, Pheng V, Inoue N, Maeda KI, Tsukamura H

    Journal of Reproduction and Development   Vol. 61   page: 351-359   2015

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  65. Design and synthesis of fluorescent probes for GPR54

    Kaneda, M., Misu, R., Ohno, H., Hirasawa, A., Ieda, N., Uenoyama, Y., Tsukamura, H., Maeda, K.I., Oishi, S. and Fujii, N.

    Bioorg. Med. Chem.   Vol. 22   page: 3325-3330   2014

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  66. KISS1 gene expression in the developing brain of female pigs in pre- and peripubertal periods.

    Ieda, N., Uenoyama, Y., Tajima, Y., Nakata, T., Kano, M., Naniwa, Y., Watanabe, Y., Minabe, S., Tomikawa, J., Inoue, N., Matsuda, F., Ohkura, S., Maeda, K.I. and Tsukamura, H

    J. Reprod. Dev.   Vol. 60   page: 312-316   2014

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  67. Oestrogen-induced activation of preoptic kisspeptin neurones may be involved in the luteinizing hormone surge in male and female Japanese monkeys

    Watanabe, Y., Uenoyama, Y., Suzuki, J., Takase, K., Suetomi, Y., Ohkura, S., Inoue, N., Maeda, K.I. and Tsukamura, H

    J. Neuroendocrinol.   Vol. 26   page: 909-917   2014

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  68. KNDy neuron as a gatekeeper of puberty onset Invited Reviewed

    Uenoyama Y, Tsukamura H, Maeda KI

    J Obstet Gynaecol Res   Vol. 40   page: 1518 - 1526   2014

  69. Microarray Analysis of Perinatal-Estrogen-Induced Changes in Gene Expression Related to Brain Sexual Differentiation in Mice

    Sakakibara M, Uenoyama Y, Minabe S, Watanabe Y, Deura C, Nakamura S, Suzuki G, Maeda K-I and Tsukamura H

    PLoS ONE   Vol. 8   page: e79437   2013.11

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  70. Effects of Full-Length Kisspeptin Administration on Follicular Development in Japanese Black Beef Cows

    Naniwa Y, Nakatsukasa K, Setsuda S, Oishi S, Fujii N, Matsuda F, Uenoyama Y, Tsukamura H, Maeda KI, Ohkura S

    J Reprod Dev   Vol. 59   page: 588–594   2013.8

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  71. Chronic peripheral administration of kappa-opioid receptor antagonist advances puberty onset associated with acceleration of pulsatile luteinizing hormone secretion in female rats

    Nakahara T, Uenoyama Y, Iwase A, Oishi S, Nakamura S, Minabe S, Watanabe Y, Deura C, Noguchi T, Fujii N, Kikkawa F, Maeda KI, Tsukamura H

    J Reprod Dev   Vol. 59   page: 479-484   2013.6

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  72. Molecular cloning and identification of the transcriptional regulatory domain of the goat neurokinin B Gene TAC3

    Suetomi Y, Matsuda F, Uenoyama Y, Maeda KI, Tsukamura H, Ohkura S

    J Reprod Dev   Vol. 59   page: 463-469   2013.3

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  73. Dynorphin-kappa opioid receptor signaling partly mediates estrogen negative feedback effect on LH pulses in female rats Reviewed

    Mostari MP, Ieda N, Deura C, Minabe S, Yamada S, Uenoyama Y, Maeda KI, Tsukamura H

      Vol. 59   page: 266–272   2013.1

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  74. Central distribution of kiss2 neurons and peri-pubertal changes in their expression in the brain of male and female red seabream Pagrus major

    Shimizu Y, Tomikawa J, Hirano K, Nanikawa Y, Akazome Y, Kanda S, Kazeto Y, Okuzawa K, Uenoyama Y, Ohkura S, Tsukamura H, Maeda KI, Gen K, Oka Y, Yamamoto N

    Gen Comp Endocrinol   Vol. 175   page: 432-442   2012

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  75. Epigenetic regulation of Kiss1 gene expression mediating estrogen-positive feedback action in the mouse brain

    Tomikawa J, Uenoyama Y, Ozawa M, Fukanuma T, Takase K, Goto T, Abe H, Ieda N, Minabe S, Deura C, Inoue N, Sanbo M, Tomita K, Hirabayashi M, Tanaka S, Imamura T, Okamura H, Maeda KI, Tsukamura H

    Proc Natl Acad Sci USA     2012

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    DOI: doi:10.1073/pnas.1114245109

  76. Oestrogen-Dependent Suppression of Pulsatile Luteinizing Hormone Secretion and Kiss1 mRNA Expression in the Arcuate Nucleus During Late Lactation in Rats Reviewed

    Yamada S, Uenoyama Y, Deura C, Minabe S, Naniwa Y, Iwata K, Kawata M, Maeda KI, Tsukamura H

    J Neuroendocrinol   Vol. 24   page: 1234-1242   2012

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  77. Different Critical Perinatal Periods and Hypothalamic Sites of Oestradiol Action in the Defeminization of LH Surge and Lordosis Capacity in the Rat

    Sakakibara M, Deura C, Minabe S, Iwata Y, Uenoyama Y, Maeda KI, Tsukamura H

    J Neuroendocrinol     2012

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    DOI: 10.1111/j.1365-2826.2012.02389.x

  78. Kisspeptin neurons mediate reflex ovulation in the musk shrew (Suncus murinus)

    Inoue N, Sasagawa K, Ikai K, Sasaki Y, Tomikawa J, Oishi S, Fujii N, Uenoyama Y, Ohmori Y, Yamamoto N, Hondo E, Maeda K and Tsukamura H

    Proc Natl Acad Sci USA   Vol. 108   page: 17527-32   2011

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  79. Central Injection of Ketone Body Suppresses Luteinizing Hormone Release via the Catecholaminergic Pathway in Female Rats

    Iwata K, Kinoshita M, Susaki N, Uenoyama Y, Tsukamura H and Maeda KI

    J Reprod Dev   Vol. 57   page: 379-384   2011

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  80. Involvement of brain ketone bodies and the noradrenergic pathway in diabetic hyperphagia in rats. Invited Reviewed

    Iwata K, Kinoshita M, Yamada S, Imamura T, Uenoyama Y, Tsukamura H and Maeda KI

    J Physiol Sci   Vol. 61   page: 103 - 113   2011

  81. Ultrastructural evidence of kisspeptin-gonadotrophin-releasing hormone interaction in the median eminence of female rats: Implication of axo-axonal regulation of GnRH release Invited Reviewed

    Uenoyama Y, Inoue N, Pheng V, Homma T, Takase K, Yamada S, Ajiki K, Ichikawa M, Okamura H, Maeda KI and Tsukamura H

    J Neuroendocrinol   Vol. 23   page: 863 - 870   2011

  82. Testicular toxicity induced by a triple neurokinin receptor antagonist in male dogs Invited Reviewed

    Noritake KI, Suzuki J, Matsuoka T, Makino T, Ohnishi H, Shimomura K, Uenoyama Y, Tsukamura H, Maeda KI and Sanbuissho A

    Reprod Toxicol   Vol. 31   page: 440 - 446   2011

  83. Involvement of neurokinin receptors in the control of pulsatile luteinizing hormone secretion in rats Invited Reviewed

    Noritake KI, Matsuoka T, Ohsawa T, Shimomura K, Sanbuissho A, Uenoyama Y, Maeda KI and Tsukamura H

    J Reprod Dev   Vol. 57   page: 409 - 415   2011

  84. Analysis of pulsatile and surge-like luteinizing hormone secretion with frequent blood sampling in female mice Invited Reviewed

    Minabe S, Uenoyama Y, Tsukamura H and Maeda KI

    J Reprod Dev   Vol. 57   page: 660 - 664   2011

  85. Molecular characterization and estrogen regulation of hypothalamic Kiss1 gene in the pig Reviewed

    Tomikawa J, Homma T, Tajima S, Shibata T, Inamoto Y, Takase K, Inoue N, Ohkura S, Uenoyama Y, Maeda KI and Tsukamura H

    Biology of Reproduction   Vol. 82   page: 313-319   2010.2

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  86. Activation of Neuropeptide FF Receptors by Kisspeptin Receptor Ligands Reviewed

    Oishi S, Misu R, Tomita K, Setsuda S, Masuda R, Ohno H, Naniwa Y, Ieda N, Inoue N, Ohkura S, Uenoyama Y, Tsukamura H, Maeda K, Hirasawa A, Tsujimoto G, Fujii N

    ACS Medicinal Chemistry Letters     page: in press   2010

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  87. Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus Reviewed

    Maeda KI, Ohkura S, Uenoyama Y, Wakabayashi Y, Oka Y, Tsukamura H, Okamura H

    Brain Res     page: in press   2010

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  88. Sexual differentiation of kisspeptin neurons responsible for sex difference in gonadotropin release in rats Invited Reviewed

    Tsukamura H, Homma T, Tomikawa J, Uenoyama Y and Maeda K

    Ann N Y Acad Sci   Vol. 1200   page: 95 - 103   2010

  89. Significance of Neonatal Testicular Sex Steroids to Defeminize Anteroventral Periventricular Kisspeptin Neurons and the GnRH/LH Surge System in Male Rats Reviewed

    Homma T., Sakakibara M., Yamada S., Kinoshita M., Iwata K., Tomikawa J., Kanazawa T., Matsui H., Takatsu Y., Ohtaki T., Matsumoto H., Uenoyama Y., Maeda K.I, Tsukamura H.

    Biology of Reproduction   Vol. 81 ( 6 ) page: 1216-25   2009.12

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  90. Potencies of Centrally- or Peripherally-Injected Full-Length Kisspeptin or Its C-Terminal Decapeptide on LH Release in Intact Male Rats Reviewed

    Pheng V., Uenoyama Y., Homma T., Inamoto Y., Takase K., Yoshizawa-Kumagaye K., Isaka S., Watanabe T.X., Ohkura S., Tomikawa J., Maeda K.I., Tsukamura H.

    Journal of Reproduction and Development   Vol. 55   page: 378-382   2009

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  91. Physiological role of metastin/kisspeptin in regulating gonadotropin-releasing hormone (GnRH) secretion in female rats Reviewed

    Ohkura, S.Uenoyama, Y.Yamada, S.Homma, T.Takase, K.Inoue, N.Maeda, K. I.Tsukamura, H.

    Peptides   Vol. 30   page: 49-56   2009

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  92. Food deprivation induces monocarboxylate transporter 2 expression in the brainstem of female rat Reviewed

    Matsuyama, S.Ohkura, S.Iwata, K.Uenoyama, Y.Tsukamura, H.Maeda, K. I.Kimura, K.

    J Reprod Dev   Vol. 55   page: 256-261   2009

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  93. Kisspeptin/metastin: A key molecule controlling two modes of gonadotrophin-releasing hormone/luteinising hormone release in female rats

    Uenoyama Y, Tsukamura H, Maeda KI

    J Neuroendocrinol   Vol. 21   page: 299 - 304   2009

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  94. Gonadotrophin-Releasing Hormone Pulse Generator Activity in the Hypothalamus of the Goat Reviewed

    Ohkura S., Takase K., Matsuyama S., Mogi K., Ichimaru T., Wakabayashi Y., Uenoyama Y., Mori Y., Steiner R.A., Tsukamura H., Maeda K.I, Okamura H.

    Journal of Neuroendocrinology   Vol. 21   page: 813-821   2009

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  95. Possible role of oestrogen in pubertal increase of Kiss1/kisspeptin expression in discrete hypothalamic areas of female rats Reviewed

    Takase K, Uenoyama Y, Inoue N, Matsui H, Yamada S, Shimizu M, Homma T, Tomikawa J, Kanda S, Matsumoto H, Oka Y, Tsukamura H, Maeda KI

    Journal of Neuroendocrinology   Vol. 21   page: 527-537   2009

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  96. Central lipoprivation-induced suppression of luteinizing hormone pulses is mediated by paraventricular catecholaminergic inputs in female rats Reviewed

    Sajapitak S, Iwata K, Shahab M, Uenoyama Y, Yamada S, Kinoshita M, Bari FY, I'Anson H, Tsukamura H, Maeda K.

    Endocrinology   Vol. 149   page: 3016-24   2008

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  97. Oestrogen-dependent stimulation of luteinising hormone release by galanin-like peptide in female rats Reviewed

    Uenoyama Y, Tsukamura H, Kinoshita M, Yamada S, Iwata K, Pheng V, Sajapitak S, Sakakibara M, Ohtaki T, Matsumoto H, Maeda KI

    J Neuroendocrinol   Vol. 20   page: 626-31   2008

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  98. Paraventricular α1- and α2-adrenergic receptors mediate hindbrain lipoprivation-induced suppression of luteinizing hormone pulses in female rats

    Sajapitak S, Uenoyama Y, Yamada S, Kinoshita M, Iwata K, Bari FY, I'Anson H, Tsukamula H, Maeda KI

    J Reprod Dev   Vol. 54   page: 198-202   2008

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  99. Inhibition of Metastin (Kisspeptin-54)-GPR 54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats. Reviewed

    Yamada S, Uenoyama Y, Kinoshita M, Iwata K, Takase K, Matsui H, Adachi S, Inoue K, Maeda KI, Tsukamura H.

    Endocrinology   Vol. 148   page: 2226-2232   2007

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  100. Involvement of Anteroventral Periventricular Metastin/Kisspeptin Neurons in Estrogen Positive Feedback Action on Luteinizing Hormone Release in Female Rats

    Adachi, S., Yamada, S., Takatsu, Y., Matsui, H., Kinoshita, M., Takase, K., Sugiura, H., Ohtaki, T., Matsumoto, H., Uenoyama, Y., Tsukamura, H., Inoue, K., and Maeda, K.

    Journal of Reproduction and Development   Vol. 53   page: 367-378   2007

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  101. Acute Lipoprivation Suppresses Pulsatile Luteinizing Hormone Secretion without Affecting Food Intake in Female Rats

    Shahab,M., Sajapitak, S., Tsukamura H., Kinoshita M., Matsuyama S., Ohkura S., Yamada S., Uenoyama Y., I'Anson, H., and Maeda K.-I.

    Journal of Reproduction and Development   Vol. 52   page: 763-772   2006

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  102. Role of Noradrenergic Receptors in the Bed Nucleus of the Stria Terminalis in Regulating Pulsatile Leteinizing Hormone Secretion in Female Rats

    Yamada, S., Uenoyama, Y., Maeda, K.-I., and Tsukamura, H.

    Journal of Reproduction and Development   Vol. 52   page: 115-121   2006

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  103. Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats

    Kinoshita, M., Tsukamura, H., Adachi, S., Matsui, H., Uenoyama, Y., Iwata, K., Yamada, S., Inoue, K., Ohtaki, T., Matsumoto, H., and Maeda, K.-I.

    Endocrinology   Vol. 146   page: 4431-4436   2005

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  104. Involvement of brainstem catecholaminergic inputs to the hypothalamic paraventricular nucleus in estrogen receptorα expression in this nucleus during different stress conditions in female rats

    Estacio, M., A., C., Tsukamura, H., Reyes, B., A., S., Uenoyama, Y., I'Anson, H. and Maeda, K.-I.

    Endocrinology   Vol. 145   page: 4917-4926   2004

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  105. The lipoxygenase pathway are involved in LH-stimulated progesterone production in bovine corpus luteum

    Taniguchi, H., Uenoyama, Y., Miyamoto, Y. and Okuda, K

    Prostaglandins and other lipid mediators   Vol. 67   page: 49-60   2002.6

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  106. Prepubertal Changes in Immunoreactive Inhibin Concentration in Blood Serum and Testicular Tissue in Holstein Bull Calves

    Matsuzaki S, Uenoyama Y, Okuda K, Watanabe G, Kitamura N, Taya K, Cruzana MBC, Yamada J

    J Vet Med Sci   Vol. 63   page: 1303-1307   2001.12

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  107. Estradiol-17b Is Produced in Bovine Corpus Luteum

    Okuda K, Uenoyama Y, Berisha B, Lange IG, Taniguchi H, Kobayashi S, Kobayashi S-I, Miyamoto A, and Schams D

    Biol Reprod   Vol. 65   page: 1634-1639   2001.12

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  108. Age-related changes in the serum levels of inhibin, FSH, LH and testosterone in Holstein bulls. Reviewed

    Matsuzaki S, Uenoyama Y, Okuda K, Watanabe G, Kitamura N, Taya K, Yamada J.

    J Reprod Dev   Vol. 46   page: 245-248   2000.8

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  109. Basic fibroblast growth factor-induced prostaglansin production and its intracellular mechanisms in cultured bovine luteal cells

    Uenoyama Y, Murakami S, Schams D, Okuda K

    J Reprod Dev   Vol. 46   page: 93-99   2000.4

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  110. Luteinizing hormone receptors in the bovine corpus luteum during the oestrous cycle and pregnancy

    Okuda K, Uenoyama Y, Naito C, Sakabe Y, Kawate N

    Reprod Fertil Dev   Vol. 11   page: 147-151   1999.11

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  111. Tumor necrosis factor a receptors in microvascular endothelial cells from bovine corpus luteum

    Okuda K, Sakumoto R, Uenoyama Y, Berisha B, Miyamoto A, Schams D

    Biol Reprod   Vol. 61   page: 1017-1022   1999.10

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  112. Noradrenaline stimulates the secretion of prostaglandin F2a in cultured endometrial cells

    Skarzynski DJ, Uenoyama Y, Kotwica J, Okuda K

    Biol Reprod   Vol. 60   page: 277-282   1999.2

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  113. Secretion of prostaglandins E2 and F2a by bovine endometrium in response to oxytocin during the estrous cycle

    Miyamoto Y, Skarzynski DJ, Uenoyama Y, Okuda K

    J Reprod Dev   Vol. 44   page: 289-295   1998.8

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  114. Progesterone stimulation by prostaglandin F2a involves the protein kinase C pathway in cultured bovine luteal cells

    Okuda K, Uenoyama Y, Lee KW, Sakumoto R, Skarzynski DJ

    J Reprod Dev   Vol. 44   page: 79-84   1998.4

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  115. Oxytocin receptors and their physiological significance in the ovary

    Okuda K, Uenoyama Y

    Reproductive Biology Update -Novel Tools for Assessment of Environmental Toxicity-     page: 297-304   1998.1

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  116. Up-regulation of oxytocin receptors in porcine endometrium by adenosine 3',5'-monophosphate

    Uenoyama Y, Hattori S, Miyake M, Okuda K

    Biol Reprod   Vol. 57   page: 723-728   1997.10

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  117. Regulation of oxytocin receptors in bovine granulosa cells.

    Uenoyama Y, Okuda K

    Biol Reprod   Vol. 57(3)   page: 569-574   1997.9

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    Language:English   Publishing type:Research paper (scientific journal)  

  118. Functional oxytocin receptors in bovine granulosa cells

    Okuda K, Uenoyama Y, Fujita Y, Iga K, Sakamoto K, Kimura T

    Biol Reprod   Vol. 56(3)   page: 625-631   1997.3

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    Language:English   Publishing type:Research paper (scientific journal)  

  119. Effects of prostaglandins and oestradiol-17b on oxytocin binding in cultured bovine luteal cells

    Okuda K, Uenoyama Y, Miyamoto A, Okano A, Schweigert FJ, Schams D.

    Reprod Fertil Dev   Vol. 7(5)   page: 1045-1051   1995.10

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    Language:English   Publishing type:Research paper (scientific journal)  

  120. Epidermal growth factor and its receptor in bovine corpus luteum during the estrous cycle Reviewed

    Okuda K, Uenoyama Y, Hwang KN, Yamada J, Wakabayashi K

    J Reprod Dev   Vol. 40   page: 349-54   1994

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 6

  1. 内分泌代謝科専門医研修ハンドブック

    上野山賀久, 束村博子( Role: Contributor ,  ホルモンの合成、分泌、輸送、代謝—概論 (3) 神経内分泌機構)

    診断と治療社  2018.4 

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    Total pages:763   Responsible for pages:16-18  

  2. The GnRH Neuron and its Control Reviewed

    Tsukamura H, Maeda KI, Uenoyama Y( Role: Contributor ,  Fetal/perinatal programming causing sexual dimorphism of the kisspeptin–GnRH neuronal network)

    Wiley  2018 

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    Total pages:517   Responsible for pages:43-60   Language:English Book type:Scholarly book

  3. Puberty: Physiology and Abnormalities Reviewed International journal

    Uenoyama Y, Inoue N, Ieda N, Pheng V, Maeda K-I, Tsukamura H( Role: Contributor ,  Maturation and physiology of hypothalamic regulation of the gonadal axis)

    Springer  2016 

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    Total pages:294   Responsible for pages:1-11   Language:English Book type:Scholarly book

  4. Kisspeptin Signaling in Reproductive Biology International journal

    Okamura H, Tsukamura H, Ohkura S, Uenoyama Y, Wakabayashi Y, Maeda KI.( Role: Contributor ,  Kisspeptin and GnRH pulse generation)

    Springer  2013 

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    Total pages:514   Responsible for pages:297-323   Language:English Book type:Scholarly book

  5. Annual Review 糖尿病・代謝・内分泌2010

    冨川順子、上野山賀久、束村博子、前多敬一郎( Role: Contributor ,  Kisspeptin/metastinと生殖機能制御)

    中外医学社  2010 

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    Total pages:259   Responsible for pages:206-212   Language:Japanese

  6. 社団法人日本動物学会 シリーズ21世紀の動物科学10巻「内分泌と生命現象」

    大蔵聡、木下美香、上野山賀久、束村博子、前多敬一郎( Role: Contributor ,  生殖機能の神経内分泌メカニズム)

    培風館  2007 

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    Total pages:256   Responsible for pages:40-76   Language:Japanese

    生殖機能を制御する神経内分泌メカニズムについて、特に性成熟のタイミングを制御するホルモン、神経伝達物質、環境要因について概説した。

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MISC 24

  1. キスペプチン受容体・GnRH受容体: キスペプチン−キスペプチン受容体シグナリングによるGnRH分泌制御メカニズム Invited International coauthorship

    井上直子、中村翔、上野山賀久、束村博子

    糖尿病・内分泌代謝科   Vol. 52   page: 476-490   2021.5

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    Language:Japanese  

  2. キスペプチンによる生殖制御機構

    家田菜穂子, 井上直子, 束村博子, 上野山賀久

    内分泌・糖尿病・代謝内科     2017

  3. 哺乳類の生殖機能制御メカニズムとその老化

    上野山賀久, 井上直子, 束村博子

    日本抗加齢医学会雑誌     2017

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    Authorship:Lead author   Language:Japanese  

  4. 視床下部による卵胞発育制御機構 Invited

    井上直子, 束村博子, 上野山賀久

    臨床婦人科産科     2016

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    Authorship:Last author   Language:Japanese  

  5. ほ乳類の性成熟を制御する脳内メカニズムの解明

    上野山賀久, 束村博子

    生物科学     2016

  6. ほ乳類の生殖機能を制御するエストロジェンのフィードバック作用を仲介する脳内メカニズム

    上野山賀久, 束村博子

    日本生殖内分泌学会雑誌     2016

  7. プロスタグランジンF2α及び性腺刺激ホルモンによる排卵同期化法を用いた豚の定時人工授精

    中田智子, 田島瑶子, 野口倫子, 上野山賀久, 大蔵聡, 前多敬一郎, 鈴木千恵, 吉岡耕治

    日獣会誌     2014

  8. 新たな中枢性繁殖制御剤のシーズ:KNDyニューロン

    前多敬一郎, 大石真也, 束村博子, 上野山賀久, 大蔵聡, 松田二子

    MPアグロジャーナル     2014

  9. ストレスが繁殖に与える影響〜内分泌学的影響と知見〜

    前多敬一郎, 束村博子, 上野山賀久

    臨床獣医     2012

  10. 繁殖障害の根本治療に向けての新たな方法論:KNDyニューロンの応用

    前多敬一郎, 大蔵聡, 松田二子, 難波陽介, 若林嘉昭, 岡村裕昭, 井上直子, 上野山賀久, 束村博子

    家畜診療     2012

  11. 卵胞発育と成熟(1) 卵胞発育の中枢制御機構

    井上直子, 上野山賀久, 大蔵聡, 束村博子, 前多敬一郎

    Hormone Frontier in Gynecology     2011

  12. キスペプチンによる繁殖機能制御機構

    上野山賀久, 大蔵聡, 井上直子, 前多敬一郎, 束村博子

    臨床化学     2011

  13. 思春期/性成熟のタイミングを決定するキスペプチン/メタスチン

    上野山賀久、大蔵聡、束村博子、前多敬一郎

    産科と婦人科     2010

  14. キスペプチン/メタスチン 繁殖を制御する新規神経ペプチド

    大蔵聡, 上野山賀久, 冨川順子, 井上直子, 束村博子, 前多敬一郎

    日本産業動物獣医師会雑誌     2010

  15. 生周期とニューロペプチド(1)キスペプチン

    本間玲実、冨川順子、上野山賀久、前多敬一郎、束村博子

    Hormone Frontier in Gynecology     2010

  16. 視床下部-下垂体-性腺軸のマスターレギュレーターとしてのメタスチン(キスペプチン)

    束村博子、上野山賀久、山田俊児、冨川順子、井上直子、大蔵聡、前多敬一郎

    ホルモンと臨床     2008

  17. メタスチン/キスペプチン-種を越えて生殖を司る神経ペプチド-

    束村博子、上野山賀久、大蔵聡、前多敬一郎

    化学と生物     2008

  18. キスペプチン(メタスチン)による繁殖機能制御とその応用

    上野山賀久、束村博子、前多敬一郎

    医学のあゆみ     2008

  19. 繁殖メカニズムの中核ペプチド、メタスチン(キスペプチン)をめぐる新しい性腺刺激剤の可能性(その2)

    前多敬一郎、上野山賀久、大蔵聡、束村博子

    家畜人工授精     2007

  20. 繁殖メカニズムの中核ペプチド、メタスチン(キスペプチン)をめぐる新しい性腺刺激剤の可能性(その1)

    前多敬一郎、上野山賀久、大蔵聡、束村博子

    家畜人工授精     2007

  21. 中枢内分泌の最新知見とその異常「メタスチン」

    上野山賀久、束村博子、前多敬一郎

    産科と婦人科     2007

  22. メタスチン (キスペプチン):新しい繁殖制御の可能性を秘めた神経ペプチド

    前多敬一郎, 上野山賀久, 束村博子, 大蔵聡

    臨床獣医     2007

  23. 黄体と子宮の機能調節におけるアポトーシスの役割とその制御

    奥田 潔、上野山賀久

    農林水産技術 研究ジャーナル     1999

  24. 妊娠成立のための卵巣機能とその調節 −黄体機能調節因子に関する最近の知見

    奥田潔, 上野山賀久, 作本亮介

    J Reprod Dev     1997

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Presentations 111

  1. 泌乳後期ラットにおけるKNDyニューロン抑制を担うエストロゲン受容体・共役コリプレッサーの発現解析

    滝沢麻里奈、井上直子、上野山賀久、束村博子

    第27回日本生殖内分泌学会  2022.12  日本生殖内分泌学会

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    Event date: 2022.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島   Country:Japan  

  2. GPR75ノックアウトラットは高脂肪食による過食・肥満・糖代謝異常を示さない

    大塚裕記、平林真澄、井上直子、束村博子、上野山賀久

    第1 7回 GPCR 研究会  2022.11  GPCR 研究会

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    Event date: 2022.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:茨城   Country:Japan  

  3. 新規遺伝子改変動物Kiss1-Creラットを用いた生殖中枢キスペプチンニューロン分布の性差および発達による変化の組織学的解析

    山田晃熙,眞野哲也,長江麻佑子,井上直子,上野山賀久,平林真澄, 束村博子

    第48回日本神経内分泌学会学術集会  2022.10  日本神経内分泌学会

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:栃木   Country:Japan  

  4. κ-オピオイド受容体発現細胞特異的およびKiss1発現細胞特異的Kiss1ノックアウトラットの生殖機能解析

    長江麻佑子、榎本悠希、米谷麻里、山田晃熙、土田仁美、平林真澄、井上直子、上野山賀久、束村博子

    第46回日本比較内分泌学会大会及びシンポジウム 東京大会  2022.10  日本比較内分泌学会大会

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  5. キスペプチンニューロン常時可視化ラットを用いた雌雄ラット脳の組織学的解析

    眞野哲也、山田晃煕、長江麻佑子、井上直子、上野山賀久、平林真澄、束村博子

    第46回日本比較内分泌学会大会及びシンポジウム  2022.10  日本比較内分泌学会

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  6. ATP-P2X2 receptor signaling is essential for the generation of GnRH/LH surgevia activation of kisspeptin neurons in the anteroventral periventricular nucleus

    Hazim Safiullah, Ryoya Yabushita, Mayuko Nagae, Masumi Hirabayashi, Yoshihisa Uenoyama, Hiroko Tsukamura, Naoko Inoue

    2022.10 

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    Event date: 2022.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  7. κ-オピオイド受容体発現細胞特異的Kiss1ノックアウト雌ラットの生殖機能解析

    長江 麻佑子,榎本 悠希,米谷 麻里,平林 真澄,井上 直子,上野山 賀久,束村 博子

    第115回 日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  8. 泌乳ラットにおけるエストロゲン依存性のKiss1発現抑制におけるエストロゲン受容体共役コリプレッサーの機能解析

    滝沢麻里奈、井上直子、上野山賀久、束村博子

    第115回 日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese  

    Venue:東京   Country:Japan  

  9. キスペプチンニューロンを蛍光により常時可視化したラットを用いた雌雄脳内の蛍光標識細胞分布の経時的解析

    山田晃熙、長江麻佑子、眞野哲也、井上直子、上野山賀久、平林真澄、束村博子

    第115回 日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  10. エストロジェンが雌ラット視床下部ダイノルフィンニューロンの活性化に及ぼす影響

    藪下 怜也,Safiullah HAZIM,束村 博子,上野山 賀久,井上 直子

    第115回日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  11. 室傍核エンケファリンニューロンがグルコース利用阻害によるLH分泌抑制/糖新生を仲介する

    土田仁美、井上直子、上野山賀久、束村博子

    第115回日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  12. 性成熟を制御するエストロジェン作用機序の解明を目指したKNDyニューロンにおけるERαコリプレッサーNcor2発現解析

    松永菜央、井上直子、束村博子、上野山賀久

    第115回日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  13. 泌乳ラットのLH分泌抑制および摂食亢進を担うオピオイドシグナリングの役割

    野々垣 弥玖,土田 仁美,井上 直子,束村 博子,上野山 賀久

    第115回日本繁殖生物学会大会  2022.9  日本繁殖生物学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  14. GPR75シグナリングは摂食を促進的に制御し高脂肪食による過食・肥満・高血糖・インスリン抵抗性を仲介する

    大塚裕記、平林真澄、井上直子、束村博子、上野山賀久

    日本畜産学会第130回大会  2022.9  日本畜産学会

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    Event date: 2022.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:WEB   Country:Japan  

  15. Histological analysis of visualized Kiss1 neurons using newly generated Kiss1-Cre rats International conference

    Koki Yamada, Mayuko Nagae, Tetsuya Mano, Naoko Inoue, Yoshihisa Uenoyama, Masumi Hirabayashi, Hiroko Tsukamura

    The international congress of neuroendocrinology (ICN 2022)   2022.8  ICN

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    Event date: 2022.8

    Language:English   Presentation type:Poster presentation  

    Venue:Glasgow   Country:United Kingdom  

  16. KNDy neurons: the gonadotropin-releasing hormone (GnRH) pulse generator in mammals Invited International conference

    Uenoyama Y, Inoue N, Tsukamura H.

    19thAAAP  2022.8  AAAP

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    Event date: 2022.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Jeju, Koria.   Country:Korea, Republic of  

  17. KNDy neurones and GnRH/LH pulse generation. Invited International conference

    Hiroko Tsukamura, Yoshihisa UENOYAMA.

    The international congress of neuroendocrinology (ICN 2022)   2022.8  ICN

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    Event date: 2022.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Glasgow   Country:United Kingdom  

  18. KNDy neurons maintain gonadotropin pulses and folliculogenesis as the GnRH pulse generator International conference

    Mayuko Nagae, Yoshihisa Uenoyama, Hitomi Tsuchida, Masumi Hirabayashi, Naoko Inoue, Hiroko Tsukamura

    The international congress of neuroendocrinology (ICN 2022)   2022.8  ICN

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    Event date: 2022.8

    Language:English   Presentation type:Poster presentation  

    Venue:Glasgow   Country:United Kingdom  

  19. Involvement of central dynorphin and β-endorphin signaling in glucoprivic LH pulse suppression and gluconeogenesis/feeding International conference

    Hitomi TSUCHIDA、Naoko INOUE、Yoshihisa UENOYAMA、Hiroko TSUKAMUTA

    The international congress of neuroendocrinology (ICN 2022)   2022.8  ICN

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    Event date: 2022.8

    Language:English   Presentation type:Poster presentation  

    Venue:Glasgow   Country:United Kingdom  

  20. DOHaD theory、胎児プログラミングを基軸とする環境内分泌学研究 発達期環境ストレスによる生殖機能不全をもたらす神経内分泌メカニズム Invited

    美辺 詩織, 岩田 衣世, 渡辺 雄貴, 石井 寛高, 井上 直子, 上野山 賀久, 束村 博子, 小澤 一史

    日本内分泌学会第 40 回内分泌代謝学サマーセミナー 2022  2022.7.7  日本内分泌学会

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    Event date: 2022.7

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:群馬  

  21. 哺乳類の卵胞発育を制御する脳内メカニズムの解明

    長江麻佑子、土田仁美、井上直子、束村博子、上野山賀久

    令和3年度日本学術振興会育志賞研究発表会  2022.3.2  日本学術振興会

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    Event date: 2022.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  22. 室傍核ダイノルフィンニューロンは泌乳ラットにおけるLHパルスの抑制を仲介する

    土田仁美, 井上直子, 上野山賀久, 束村博子

    第26回日本生殖内分泌学会学術集会  2022.1  日本生殖内分泌学会

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    Event date: 2022.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:石川   Country:Japan  

  23. Kiss1細胞常時可視化遺伝子改変ラットを用いた雌雄脳内Kiss1細胞分布の経時的解析

    山田晃熙、長江麻佑子、眞野哲也、井上直子、上野山賀久、平林真澄、束村博

    第26回日本生殖内分泌学会学術集会  2022.1.8  日本生殖内分泌学会

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    Event date: 2022.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:石川   Country:Japan  

  24. The Neural Pathway Mediating the Suppression of Reproductive Function during Lactation

    2022.1.7  WEB開催

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    Event date: 2022.1

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  25. 遺伝子改変ラットを用いた哺乳類の卵胞発育中枢の同定

    長江麻佑子、土田仁美、井上直子、束村博子、上野山賀久

    愛知県農学系4機関による研究交流会  2021.12.17  愛知県農学系4機関

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    Event date: 2021.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  26. GPR75シグナリングは高脂肪食による過食・肥満・糖代謝異常を仲介する

    大塚裕記, 平林真澄, 井上直子, 束村博子, 上野山賀久

    第16回 GPCR研究会  2021.11  GPCR研究会

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    Event date: 2021.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  27. β-エンドルフィン-µオピオイド受容体シグナリングは低栄養による生殖機能抑制と糖新生/摂食の誘起を仲介する

    土田仁美, 井上直子, 上野山賀久, 束村博子

    第16回 GPCR研究会  2021.11  GPCR研究会

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    Event date: 2021.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  28. 卵胞発育を司るGnRHパルス発生機構の同定

    長江麻佑子、土田仁美、井上直子、束村博子、上野山賀久

    第45回日本比較内分泌学会  2021.11  日本比較内分泌学会

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    Event date: 2021.11 - 2021.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  29. 脳内β-エンドルフィン-µオピオイド受容体シグナリングがグルコース利用阻害によるLH分泌抑制/糖新生/摂食誘起を仲介する

    土田仁美, 井上直子, 上野山賀久, 束村博子

    第45回日本比較内分泌学会  2021.11  日本比較内分泌学会

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    Event date: 2021.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  30. 性成熟を制御する弓状核KNDyニューロン Invited

    上野山賀久、井上直子、束村博子

    第54回日本小児内分泌学会学術集会  2021.10  日本小児内分泌学会

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:札幌(WEB参加)   Country:Japan  

  31. アデノ随伴ウイルスベクターを用いた効率的なTfap2c-T2A-tdTomatoノックインラットの作製

    長江麻佑子、及川真実、上野山賀久、平林真澄、小林俊寛

    第11回名古屋大学医学系研究科・生理学研究所合同シンポジウム  2021.9.25  名古屋大学医学系研究科

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:WEB開催   Country:Japan  

  32. 室傍核ダイノルフィンAニューロンは泌乳ラットにおけるLHパルス抑制を仲介する

    土田仁美, 井上直子, 上野山賀久, 束村博子

    第114回日本繁殖生物学会大会  2021.9  日本繁殖生物学会

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:WEB開催   Country:Japan  

  33. GnRH パルスジェネレーター解析のための新規 Cre 発現ラットの作製

    長江麻佑子、小林俊寛、三宝誠、平林真澄、水野直彬、中内啓光、榎本悠希、井上直子、束村博子、上野山賀久

    第114回日本繁殖生物学会大会  2021.9  日本繁殖生物学会

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:WEB開催   Country:Japan  

  34. 雌ラットキスペプチンニューロンにおけるSNAP-25遺伝子の発現解析

    山田晃熙、井上直子、上野山賀久、束村博子

    第114回日本繁殖生物学会大会  2021.9  日本繁殖生物学会

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    Event date: 2021.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  35. 泌乳ラットにおけるKiss1発現抑制を担うエストロゲン受容体共役コリプレッサーの探索

    滝沢麻里奈, 井上直子, 上野山賀久, 束村博子

    第114回日本繁殖生物学会大会  2021.9  日本繁殖生物学会

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:WEB開催   Country:Japan  

  36. Search for purinergic neurons projecting to the vicinity of the kisspeptin neurons in the anteroventral periventricular nucleus by retrograde tracing

    Safiullah HAZIM, Yoshihisa UENOYAMA, Hiroko TSUKAMURA, Naoko INOUE

    2021.9 

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    Event date: 2021.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  37. Brain Mechanism of Puberty Onset in Mammals Invited International conference

    Uenoyama Y and Tsukamura H

    5th Asian Forum on Chronobiology   2021.7.15  Chinese Society for Biological Rhythm-Chinese Society of Cell Biology

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    Event date: 2021.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Kaifeng  

  38. Kiss1 KOラット弓状核Tac3ニューロンへのKiss1遺伝子導入によるGnRHパルスと卵胞発育の回復

    上野山賀久、長江麻佑子、岡本沙季、土田仁美、井上直子、束村博子

    第94回日本内分泌学会学術総会  2021.4 

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    Event date: 2021.4

  39. β-エンドルフィン-μ-オピオイド受容体シグナリングはグルコース利用阻害による生殖機能抑制を仲介する

    土田仁美, 河合成美、井上直子, 上野山賀久, 束村博子

    第94回日本内分泌学会学術総会  2021.4  日本内分泌学会

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    Event date: 2021.4

    Language:Japanese   Presentation type:Poster presentation  

    Venue:WEB開催   Country:Japan  

  40. KNDy neurons as the GnRH pulse generator: Twenty percent of KNDy neurons are enough to maintain gonadotropin pulse and folliculogenesis Invited International conference

    Uenoyama Y

    Kisspeptin+ Virtual Conference 

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    Event date: 2021.4

    Language:English   Presentation type:Oral presentation (invited, special)  

  41. KNDyニューロン復元によるゴナドトロピン放出ホルモン (GnRH) パルスと卵胞発育の回復

    上野山賀久、長江麻佑子、岡本沙季、土田仁美、井上直子、束村博子

    日本畜産学会第128回大会  2021.3 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  42. Generation of Genetically Modified Rats for Analysis of Neural Mechanism Involved in GnRH Pulse Generation

    Mayuko Nagae, Toshihiro Kobayashi, Makoto Sanbo, Masumi Hirabayashi, Naoko Inoue, Hiroko Tsukamura, Yoshihisa Uenoyama

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    Event date: 2021.1

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  43. 室傍核ダイノルフィンニューロンがグルコース利用阻害による生殖機能抑制を仲介する

    土田 仁美,井上 直子,上野山 賀久,束村 博子

    第25回日本生殖内分泌学会 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  44. 弓状核特異的Kiss1レスキュー/ノックアウトラットを用いたGnRHパルスジェネレーターの同定

    長江麻佑子、上野山賀久、岡本沙季、土田仁美、池上花奈、後藤哲平、三宝誠、平林真澄、小林憲太、井上直子、束村博子

    第25回日本生殖内分泌学会 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  45. ATP-プリン受容体シグナリングによるLHサージ制御機構 ~ATPはキスペプチンニューロン不死化細胞のCa2+を上昇させる~

    土肥由莉、大塚裕記、上野山賀久、束村博子、井上直子

    東海畜産学会 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Oral presentation (general)  

  46. 弓状核Kiss1発現を制御するエストロジェン受容体αコリプレッサーの探索

    宮崎紗衣、井上直子、束村博子、上野山賀久

    東海畜産学会 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Oral presentation (general)  

  47. 低栄養による生殖機能抑制は室傍核ダイノルフィンニューロンによる弓状核キスペプチンニューロンの抑制によって仲介される

    土田 仁美,井上 直子,上野山 賀久,束村 博子

    第113回日本繁殖生物学会 

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    Event date: 2020.9

  48. ATP-プリン受容体シグナリングによるAVPVキスペプチンニューロン由来不死化細胞株活性化の検討

    土肥由莉、上野山賀久、束村博子、井上直子

    第113回日本繁殖生物学会 

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    Event date: 2020.9

  49. Kiss1発現を制御するエストロジェン受容体αコリプレッサーの探索

    宮崎紗衣、井上直子、束村博子、上野山賀久

    第113回日本繁殖生物学会 

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    Event date: 2020.9

  50. 遺伝子改変ラットを用いた卵胞発育中枢の同定

    長江麻佑子、上野山賀久、井上直子、小林憲太、平林真澄、束村博子

    第10回名古屋大学医学系研究科・生理学研究所合同シンポジウム 

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    Event date: 2020.9

  51. 栄養状態が性成熟の到来を制御するメカニズムの解明

    上野山賀久、Majarune Sutisa、Pelden Nima、井上直子、束村博子

    第46回日本神経内分泌学会学術集会 

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    Event date: 2019.10

  52. Brain mechanism regulating puberty onset in mammals Invited International conference

    Uenoyama Y

    4th World Congress of Reproductive Biology 

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    Event date: 2017.9

    Language:English   Presentation type:Oral presentation (invited, special)  

  53. ほ乳類の繁殖機能制御機構におけるキスペプチンの役割に関する研究

    上野山賀久

    第110回日本繁殖生物学会 

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    Event date: 2017.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  54. Kiss1ノックアウトラットを用いた生殖中枢メカニズムの解明

    上野山賀久

    第10回ラットリソースリサーチ研究会 

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    Event date: 2017.2

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  55. Hypothalamic regulation of the gonadal axis in mammals

    Uenoyama Y

    3rd of the Joint Symposium of Thai and Japanese Societies for Animal Reproduction 

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    Event date: 2016.1

  56. Kisspeptin neurons: as a master regulator of reproduction in mammals.

    Uenoyama Y

    International Seminar: Current boundaries of the expanding landscape of insulin-like activities and beyond 

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    Event date: 2015.9

  57. 卵胞発育の中枢制御メカニズム

    上野山賀久

    第158回日本獣医学会学術集会・日本獣医解剖学会シンポジウム「生殖を司る脳と卵巣のクロストーク 〜卵胞発育から受精まで〜」 

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    Event date: 2015.9

  58. Kiss1ノックアウト雄ラットにおける生殖機能不全

    上野山賀久、中村翔、池上花奈、美辺詩織、家田菜穂子、冨川順子、後藤哲平、前多敬一郎、束村博子

    第88回日本内分泌学会学術総会 

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    Event date: 2015.4

  59. Lack of gonadotropin release in Kiss1 knockout male rats International conference

    Uenoyama Y, Nakamura S, Hayakawa Y, Ikegami K, Deura C, Minabe S, Tomikawa J, Goto T, Ieda N, Sanbo M, Tamura C, Hirabayashi M, Maeda K-I, Tsukamura H

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    Event date: 2014.9

  60. Kiss1ノックアウト雄ラットにおけるゴナドトロピン分泌不全

    上野山賀久、中村翔、池上花奈、美辺詩織、家田菜穂子、冨川順子、後藤哲平、田村千尋、三宝誠、平林真澄、前多敬一郎、束村博子

    第40回日本神経内分泌学会学術集会/第38回日本比較内分泌学会大会 合同大会 

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    Event date: 2013.10

  61. キスペプチンニューロンのGnRH分泌制御におけるハブニューロンとしての役割

    上野山賀久、中村翔、池上花奈、冨川順子、美辺詩織、後藤哲平、田村千尋、三寳誠、平林真澄、前多敬一郎、束村博子

    第86回日本内分泌学会学術総会 

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    Event date: 2013.4

  62. Indispensable role of kisspeptin in controlling gonadotropin-releasing hormone release in mammals

    Uenoyama Y, Nakamura S, Tsukamura H, Maeda K-I

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    Event date: 2013.3

    Language:English   Presentation type:Oral presentation (invited, special)  

  63. キスペプチンニューロンは興奮性アミノ酸による GnRH/LH 分泌刺激を仲介する

    上野山賀久、中村 翔、早川 由起、池上 花奈、冨川 順子、美辺 詩織、後藤 哲平、家田菜穂子、 田村 千尋、三寳 誠、平林 真澄、前多敬一郎、束村 博子

    第17回日本生殖内分泌学会学術集会 

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    Event date: 2012.12

  64. Kiss1 knockout rats to define role of kisspeptin in regulating luteinizing hormone secretion

    Uenoyama Y, Nakamura S, Hayakawa Y, Minabe S, Tomikawa J, Goto T, Ieda N, Sanbo M, Tamura C, Hirabayashi M, Maeda K-I, Tsukamura H

    2nd World Conference on Kisspeptin Signaling in the Brain 

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    Event date: 2012.11

  65. Kiss1ノックアウトラットを用いたキスペプチンの生殖機能制御における役割の証明

    上野山賀久、中村翔、早川由起、池上花奈、冨川順子、美辺詩織、後藤哲平、家田菜穂子、田村千尋、三 誠、平林真澄、前多敬一郎、束村博子

    第39回日本神経内分泌学会学術集会 

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    Event date: 2012.9

  66. 生殖内分泌:性成熟を制御する神経内分泌機構

    上野山賀久

    生殖発生毒性専門家教育講習会 

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    Event date: 2012.7

  67. ラット正中隆起におけるキスペプチン (Kp) とGnRHのインタラクション

    上野山賀久、井上直子、Vutha Pheng、本間玲実、高瀬健志、山田俊児、安食京子、市川真澄、岡村裕昭、前多敬一郎、束村博子

    第36回日本比較内分泌学会大会およびシンポジウム 

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    Event date: 2011.11

  68. Morphological and functional interactions between kisspeptin and GnRH neurons at the median eminence in female rats

    Uenoyama Y., Inoue N., Vutha P., Homma T., Takase K., Yamada S., Ajiki K., Ichikawa M., Okamura H., Maeda K.-I., Tsukamura H.

    The Second World Congress on Reproductive Biology 

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    Event date: 2011.10

  69. Kisspeptin: a key molecule controlling the activity of the hypothalamo-pituitary-gonadal axis Invited

    Uenoyama Y, Ohkura S, Tsukamura H, Maeda K-I

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (invited, special)  

  70. キスペプチンは正中隆起において性腺刺激ホルモン放出ホルモン分泌を制御する

    上野山賀久、井上直子、PHENG Vutha、本間玲実、高瀬健志、山田俊児、安食京子、市川眞澄、岡村裕昭、前多敬一郎、束村博子

    第104回日本繁殖生物学会大会 

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    Event date: 2011.9

  71. 種を越えて生殖を制御する神経ペプチド、メタスチン/キスペプチン

    上野山賀久、大蔵聡、井上直子、冨川順子、束村博子、前多敬一郎

    セミナー「キスペプチンを中心とした生殖制御系研究の最前線」 

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    Event date: 2010.12

  72. The role of neural inputs from the posterior arcuate nucleus in pulsatile luteinizing hormone release in ovariectomized rats International conference

    Uenoyama Y, Watanabe S, Iwata K, Ohkura S, Maeda K-I and Tsukamura H

    43rd Annual Meeting for Society for the Study of Reproduction 

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    Event date: 2010.7 - 2010.8

    Language:English  

  73. Two populations of kisspeptin neurons control two modes of GnRH/LH release International conference

    Uenoyama Y, Tomikawa J, Ohkura S, Tsukamura H and Maeda K-I

    Comparative Endocrinology of Kisspeptin as a Satellite Symposium of the 14th International Congress of Endocrinology 

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    Event date: 2010.3

    Language:English  

  74. Acute trapping of peripubertal kisspeptin or leptin with antibodies to determine factors triggering the onset of puberty in female rats International conference

    Uenoyama Y, Takase K, Hirata J, Tanaka A, Tsukamura H, Maeda K-I

    14th International Congress of Endocrinology 

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    Event date: 2010.3

  75. Potencies of full-length kisspeptin or its C-terminal decapeptide on luteinizing hormone release in intact male rats International conference

    The 39th Annual Meeting of the Society for Neuroscience 2009 

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    Event date: 2009.10

    Language:English  

  76. Decreased gonadal activities by active immunization against kisspeptin in rats International conference

    1st World Conference of Kisspeptin Signaling in the Brain 

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    Event date: 2008.10

    Language:English   Presentation type:Poster presentation  

  77. ラットにおけるメタスチン/キスペプチンに対する能動免疫による性腺機能の低下

    上野山賀久、井上直子、長谷川浩一、冨川順子、束村博子、前多敬一郎

    第101回日本繁殖生物学会大会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  78. 性成熟のタイミングを決定するメタスチン/キスペプチン

    上野山賀久

    第101回日本繁殖生物学会大会ミニシンポジウム 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  79. Kisspeptin/metastin: A key molecule controlling two modes of GnRH/LH release in female rats Invited International conference

    US/JAPAN Neurosteroid Symposium 2008 

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    Event date: 2008.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  80. 未成熟雌ラットにおける脳内メタスチン発現と黄体形成ホルモン (LH) 分泌に対するエストロジェンの抑制作用

    上野山賀久、高瀬健志、清水基道、束村博子、前多敬一郎

    第35回日本神経内分泌学会 第23回日本下垂体研究会 合同学術集会 

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    Event date: 2008.8

  81. Metastin/kisspeptin neurons: A missing link for mechanism generating two modes of GnRH/LH release International conference

    Uenoyama Y, Tsukamura H, Maeda K-I

    The 4th JSAR-KSAR Joint Symposium on “Recent Advences in Animal Reproductive Biotechnology” 

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    Event date: 2008.6

    Language:English   Presentation type:Oral presentation (invited, special)  

  82. Estrogenic regulation of pubertal KiSS-1 mRNA expression in female rats International conference

    Uenoyama Y, Takase K, Shimizu M, Tsukamura H, Maeda K-I

    1st World Congress of Reproductive Biology 

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    Event date: 2008.5

    Language:English   Presentation type:Poster presentation  

  83. 性成熟のタイミングを制御するメタスチンの発現調節機構

    上野山賀久、清水基道、高瀬健志、束村博子、前多敬一郎

    第109回日本畜産学会大会 

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    Event date: 2008.3

  84. Stimulatory effect of galanin-like peptide (GALP) on luteinizing hormone release in female rats

    Uenoyama Y, Tsukamura H, Kinoshita M, Yamada S, Sajapitak S, Sakakibara M, Maeda K-I

    37th annual meeting of the Society for Neuroscience 

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    Event date: 2007.11

    Language:English  

  85. 雌ラットの黄体形成ホルモン分泌におよぼすgalanin-like peptideの影響

    上野山賀久、木下美香、山田俊児、Somchai SAJAPITAK、榊原基嗣、束村博子、前多敬一郎

    第100回日本繁殖生物学会 

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    Event date: 2007.10

  86. 性成熟のタイミングを制御するメカニズム

    上野山賀久

    21世紀の食糧生産・生物活用のための先端アグリサイエンス第1回シンポジウム 

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    Event date: 2007.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  87. The role of metastin in timing the onset of puberty International conference

    Uenoyama Y.

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    Event date: 2006.8

    Language:English   Presentation type:Oral presentation (invited, special)  

  88. 抗メタスチン抗体の脳内投与により性成熟が遅延する

    上野山賀久、高瀬健志、平田淳也、束村博子、前多敬一郎

    第29回日本神経科学大会 

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    Event date: 2006.7

    Language:English   Presentation type:Poster presentation  

  89. Prolongation of puberty onset by immunoneutralizing central metastin in female rats

    Uenoyama Y, Takase K, Hirata J, Matsumoto H, Tsukamura H, Maeda K-I

    88th annual meeting of the Endocrine Society 

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    Event date: 2006.6

    Language:English  

  90. 性成熟前のGnRH/LH 分泌抑制を担うエストロジェン作用部位の同定

    上野山賀久、田中晃、Helen I’Anson、束村博子、前多敬一郎.

    低次脳機能研究会2006 

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    Event date: 2006

  91. Estrogen feedback action sites for prepubertal suppression of luteinizing hormone secretion in ad lib-fed or food-restricted female rats

    Uenoyama Y, Tanaka A, Oka Y, I'Anson H, Tsukamura H, Maeda K-I

    35th annual meeting of the Society for Neuroscience 

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    Event date: 2005.11

    Language:English  

  92. Sexually differentiated mechanism of steroid feedback action controlling the peripubertal changes in gonadotropin-releasing hormone/luteinizing hormone secretion in rats

    Uenoyama Y, Tanaka A, Hirata J, Takase K, Tsukamura H, Maeda K-I

    87th annual meeting of the Endocrine Society 

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    Event date: 2005.6

    Language:English  

  93. メタスチンによる性成熟のタイミングの制御

    上野山賀久、平田淳也、高瀬健志、束村博子、前多敬一郎

    第2回GPCR研究会 

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    Event date: 2005.5

    Language:Japanese   Presentation type:Poster presentation  

  94. 雄ラットの性成熟を制御するアンドロジェンの新規なフィードバック作用部位

    上野山賀久、束村博子、前多敬一郎

    第97回日本繁殖生物学会 

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    Event date: 2004.9

  95. 性成熟のタイミングを制御する性ステロイドのフィードバック機構とその性差 Invited

    上野山賀久、田中晃、束村博子、前多敬一郎

    日本下垂体研究会第19回学術集会 

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    Event date: 2004.8

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  96. Galanin-like peptideと生殖機能

    上野山賀久、木下美香、Somchai Sajapotak、山田俊児、榊原基嗣、束村博子、前多敬一郎

    第1回GPCR研究会 

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    Event date: 2004.5

    Language:Japanese   Presentation type:Oral presentation (general)  

  97. Role of androgen feedback in peripubertal changes in luteinizing hormone (LH) secretion in male rats International conference

    Uenoyama Y, Tanaka A, Tsukamura H, Maeda K-I

    5th Congress of the Asia and Oceania Society for Comparative Endocrinology 

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    Event date: 2004.3

  98. 雌ラットの性成熟を制御するエストロジェンフィードバック作用部位

    上野山賀久、田中晃、束村博子、前多敬一郎

    第96回日本繁殖生物学会 

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    Event date: 2003.9

  99. 性成熟を制御するエストロジェンフィードバックサイト

    上野山賀久

    低次脳機能研究会2002 

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    Event date: 2002

  100. 雌ラットの性成熟におけるエネルギーレベルとエストロジェン (E) フィードバック機構の役割

    上野山賀久、田中晃、ヘレン・アイアンソン、束村博子、前多敬一郎

    第 94 回日本繁殖生物学会 

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    Event date: 2001.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  101. Growth Restrictedラットの性成熟におけるエストロジェンフィードバック機構の役割

    上野山賀久,田中晃,ヘレン・アイアンソン,束村博子,前多敬一郎

    下垂体研究会第 16 回学術集会 

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    Event date: 2001.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  102. Effect of immunoneutralization of leptin on the timing of puberty in female rats. International conference

    Uenoyama, Y., Tanaka, A., I'Anson, H, Tsukamura, H. and Maeda, K.-I.

    Brain, Nose and Pituitary-International Symposium 

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    Event date: 2000.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  103. ウシ黄体のプロスタグランジン (PG) 産生におよぼす線維芽細胞成長因子 (bFGF) の影響とその細胞内シグナル伝達機構

    上野山賀久、Schams D、奥田潔

    第 97 回日本畜産学会 

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    Event date: 2000.3

    Language:Japanese  

    Country:Japan  

  104. Evidence for tumor necrosis factor-a receptor and its possible roles in microvascular endothelial cells from bovine corpus luteum. International conference

    Uenoyama Y, Sakumoto R, Miyamoto A, Berisha B, Schams D, Okuda K

    32 nd Annual Meeting for Society for the Study of Reproduction 

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    Event date: 1999.7 - 1999.8

    Language:English   Presentation type:Poster presentation  

  105. Prostaglandin F2α secretion by cultured bovine endometrial cells in response to noradrenaline. International conference

    31st Annual Meeting for Society for the Study of Reproduction 

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    Event date: 1998.8

    Language:English   Presentation type:Poster presentation  

  106. ウシ顆粒層細胞のエストラジオール分泌におよぼすオキシトシンの影響

    上野山賀久、奥田潔

    第90回日本繁殖生物学会 

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    Event date: 1997.9

    Language:Japanese  

    Country:Japan  

  107. cAMP can induce oxytocin receptors in the porcine endometrial cells. International conference

    30th Annual Meeting for Society for the Study of Reproduction 

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    Event date: 1997.8

    Language:English  

  108. ブタ子宮内膜のオキシトシンレセプター調節機構に関する研究

    上野山賀久、服部慎一、奥田潔

    第92回日本畜産学会 

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    Event date: 1997.3

    Language:Japanese  

    Country:Japan  

  109. ウシ顆粒層細胞のオキシトシンレセプター濃度におよぼす性腺刺激ホルモンの影響

    上野山賀久、堀川京子、奥田潔

    第 89 回日本繁殖生物学会 

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    Event date: 1996.10

    Language:Japanese  

    Country:Japan  

  110. 培養ウシ顆粒層細胞のオキシトシンレセプターに関する研究

    野山賀久、奥田潔、堀川京子、丹羽晧二

    第86回家畜繁殖学会 

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    Event date: 1994.9

  111. プロスタグランジン (PG) F2αによるウシ黄体オキシトシン (OT) レセプター調節機構に関する研究

    上野山賀久、奥田潔、丹羽晧二

    第88回日本畜産学会 

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    Event date: 1994.3

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Research Project for Joint Research, Competitive Funding, etc. 5

  1. カンボジアにおける熱帯酪農の確立:プノンペン近郊小規模農家における酪農の現状と普及に向けた課題の発掘 International coauthorship

    2018.4 - 2019.3

    平成30年度「乳の社会文化」学術研究 

    上野山賀久

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\975886

  2. 生殖制御中枢ニューロン上のG蛋白質共役型受容体とリガンドの同定

    2016.8 - 2017.3

    科学研究費挑戦セーフティネット 

    上野山賀久

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    Grant amount:\950000

  3. 効率的な家畜生産に資する生殖中枢メカニズムの解明

    2015.6 - 2016.3

    伊藤記念財団研究助成  

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    Authorship:Principal investigator  Grant type:Competitive

  4. 性成熟期における性腺刺激ホルモン放出ホルモン分泌調節機構の解明

    2003.6 - 2004.3

    伊藤記念財団研究助成 

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    Grant type:Competitive

    性成熟期における性腺刺激ホルモン放出ホルモン分泌抑制に関わるエストロジェンの作用部位を同定した。

  5. 性成熟制御機構におけるレプチンの生理的役割の解明

    2001.5

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    委任経理金

KAKENHI (Grants-in-Aid for Scientific Research) 6

  1. 受容体GPR75を介した過食・肥満の新規メカニズム解明と抗肥満薬シーズの探索

    Grant number:22K19245  2022.6 - 2024.3

    挑戦的研究(萌芽) 

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    Authorship:Principal investigator  Grant type:Competitive

  2. 温暖化による家畜繁殖能低下の克服に資する脳熱センサーの繁殖中枢調節システムの解明

    2020.4 - 2024.3

    日本学術振興会  科学研究費補助金   基盤研究(B)

    上野山 賀久

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\17550000 ( Direct Cost: \13500000 、 Indirect Cost:\4050000 )

  3. ATP-プリン受容体シグナリングによる哺乳類の排卵中枢制御メカニズムの解明

    2019.4 - 2023.3

    科学研究費補助金   基盤研究(B)

    井上 直子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\17420000 ( Direct Cost: \13400000 、 Indirect Cost:\4020000 )

  4. 家畜繁殖向上に資する排卵・卵胞発育制御を担うエストロゲンフィードバック機構の解明

    2018.4 - 2022.3

    科学研究費補助金   基盤研究(A)

    束村 博子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\44980000 ( Direct Cost: \34600000 、 Indirect Cost:\10380000 )

  5. 性腺刺激ホルモン放出ホルモンニューロン上のG蛋白質共役型受容体とリガンドの同定

    2011.4 - 2014.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Competitive

  6. 生殖機能と摂食行動を制御する脳内のエネルギーセンシングメカニズムの解明

    2006.4 - 2010.3

    科学研究費補助金 

    前多敬一郎

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    Authorship:Coinvestigator(s)  Grant type:Competitive

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Teaching Experience (On-campus) 1

  1. Advanced Animal Reproduction

    2020

 

Social Contribution 3

  1. 共同通信:先天的不妊モデル動物の繁殖能力の回復に成功-卵胞発育を司る繁殖中枢ニューロンを同定-

    Role(s):Media coverage

    共同通信  共同通信  2021.1 - 2021.2

  2. NHK:先天的不妊モデル動物の繁殖能力の回復に成功-卵胞発育を司る繁殖中枢ニューロンを同定-

    Role(s):Media coverage

    NHK  NHKニュース  2021.1 - 2021.2

  3. Forbes: Restoring Function To KNDy Neurons In Brain Could Reverse Infertility

    Role(s):Media coverage

    Forbes  Forbes  2021.1

Media Coverage 23

  1. BioNews: Hormone 'pulses' that govern fertility are regulated by brain cells Internet

    BioNews  BioNews  https://www.bionews.org.uk/page_155259  2021.3

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    Author:Other 

  2. AlphaGalileo: Study finds potential solution to the declining birthrate particularly seen in developed countries Internet

    AlphaGalileo  AlphaGalileo  https://www.alphagalileo.org/en-gb/Item-Display/ItemId/205636?returnurl=https://www.alphagalileo.org/en-gb/Item-Display/ItemId/205636  2021.3

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    Author:Other 

  3. USACO:KNDyニューロンが性腺刺激ホルモン分泌を制御し、卵胞発育を司る繁殖中枢であることを証明 Internet

    https://www.usaco.co.jp/article/detail.html?itemid=1400&dispmid=610  2021.2

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    Author:Myself 

  4. NHK:ネズミの生殖機能回復研究で成功 TV or radio program

    NHK  NHKニュース  2021.2

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    Author:Other 

  5. Forbes: Restoring Function To KNDy Neurons In Brain Could Reverse Infertility Internet

    Forbes  Forbes  https://www.forbes.com/sites/helenalbert/2021/01/30/restoring-function-to-kndy-neurons-in-brain-could-reverse-infertility/?sh=35e7e7284077  2021.1

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    Author:Other 

  6. FLIPBOARD: Restoring Function To KNDy Neurons In Brain Could Reverse Infertility Internet

    FLIPBOARD  FLIPBOARD  https://flipboard.com/@forbes/restoring-function-to-kndy-neurons-in-brain-could-reverse-infertility/a-7USn4NM2T-OJorJ8AWLaIQ%3Aa%3A3199486-1abdc5c78a%2Fforbes.com  2021.1

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    Author:Other 

  7. 医療NEWS:先天的不妊モデル動物の繁殖能力の回復に成功 Internet

    医療NEWS  医療NEWS  http://www.qlifepro.com/news/20210127/kndy.html  2021.1

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    Author:Other 

  8. 日経新聞:先天的不妊モデル動物の繁殖能力の回復に成功-卵胞発育を司る繁殖中枢ニューロンを同定- Internet

    日本経済新聞  日本経済新聞  https://www.nikkei.com/article/DGXLRSP603800_W1A120C2000000/  2021.1

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    Author:Other 

  9. La Razon: Consiguen recuperar la función ovárica en mamíferos infértiles Internet

    La Razon:  La Razon:  https://www.larazon.es/salud/20210126/j3l7fafsgjbw3lgrsek47mzjia.html  2021.1

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    Author:Other 

  10. Infosalus: Consiguen la recuperación de la función ovárica en mamíferos infértiles Internet

    Infosalus  Infosalus  https://www.infosalus.com/salud-investigacion/noticia-consiguen-recuperacion-funcion-ovarica-mamiferos-infertiles-20210126074436.html  2021.1

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    Author:Other 

  11. Samachar Central: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    Samachar Central:  Samachar Central:  https://samacharcentral.com/recovery-of-ovarian-function-in-infertile-mammals-lacking-gonadotropin-release/  2021.1

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    Author:Other 

  12. Axón Comunicación: Consiguen la recuperación de la función ovárica en mamíferos infértiles, lo que sugiere una nueva terapia en humanos Internet

    Axón Comunicación  Axón Comunicación  https://axoncomunicacion.net/consiguen-la-recuperacion-de-la-funcion-ovarica-en-mamiferos-infertiles-lo-que-sugiere-una-nueva-terapia-en-humanos/  2021.1

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    Author:Other 

  13. notimerica: Consiguen la recuperación de la función ovárica en mamíferos infértiles Internet

    notimerica  notimerica  https://www.notimerica.com/vida/noticia-consiguen-recuperacion-funcion-ovarica-mamiferos-infertiles-20210126074455.html  2021.1

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    Author:Other 

  14. FuturoProssimo: Ovarian function recovered in infertile mammals without gonadotropins Internet

    FuturoProssimo  FuturoProssimo  https://en.futuroprossimo.it/2021/01/funzione-ovarica-recuperata-in-mammiferi-infertili-senza-gonadotropine/  2021.1

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    Author:Other 

  15. 日本の研究.com:先天的不妊モデル動物の繁殖能力の回復に成功-卵胞発育を司る繁殖中枢ニューロンを同定- Internet

    日本の研究.com  https://research-er.jp/articles/view/95989  2021.1

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    Author:Other 

  16. NEWS BREAK: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    NEWS BREAK  NEWS BREAK  https://www.newsbreak.com/news/2151270249151/recovery-of-ovarian-function-in-infertile-mammals-lacking-gonadotropin-release  2021.1

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    Author:Other 

  17. Punchng.News: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    Punchng.News  Punchng.News  https://punchng.news/recovery-of-ovarian-function-in-infertile-mammals-lacking-gonadotropin-release.html  2021.1

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    Author:Other 

  18. Florida News Times: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    Florida News Times  Florida News Times  https://floridanewstimes.com/restoration-of-ovarian-function-in-infertile-mammals-lacking-gonadotropin-release/107422/  2021.1

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    Author:Other 

  19. phys.org: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    phys.org  phys.org  https://phys.org/news/2021-01-recovery-ovarian-function-infertile-mammals.html  2021.1

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    Author:Other 

  20. Biotech World: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    Biotech World  Biotech World  https://biotechinout.xyz/2021/01/25/recovery-of-ovarian-function-in-infertile-mammals-lacking-gonadotropin-release/  2021.1

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    Author:Other 

  21. EurekAlert!: Recovery of ovarian function in infertile mammals lacking gonadotropin release Internet

    https://www.eurekalert.org/pub_releases/2021-01/nu-roo012121.php  2021.1

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    Author:Other 

  22. USACO:室傍核ダイノルフィンAニューロンは低栄養による生殖機能抑制を仲介する Internet

    https://www.usaco.co.jp/article/detail.html?itemid=1346&dispmid=610  2020.11

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    Author:Myself 

  23. cope: Consiguen la recuperación de la función ovárica en mamíferos infértiles, lo que sugiere una nueva terapia en humanos Internet

    cope  cope  https://www.cope.es/actualidad/sociedad/noticias/consiguen-recuperacion-funcion-ovarica-mamiferos-infertiles-que-sugiere-una-nueva-terapia-humanos-20210126_1105977  2010.1

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    Author:Other 

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Academic Activities 9

  1. Kisspeptin2022 International contribution

    Role(s):Planning, management, etc., Peer review

    Drs. Mike Lehman and Waljit Dhillo  2021.10

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    Type:Academic society, research group, etc. 

  2. 日本内分泌学会EJ誌編集委員 International contribution

    Role(s):Planning, management, etc., Peer review

    日本内分泌学会  2021.7

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    Type:Academic society, research group, etc. 

  3. 日本生殖内分泌学会評議員 International contribution

    Role(s):Planning, management, etc.

    日本生殖内分泌学会  2021.5

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    Type:Academic society, research group, etc. 

  4. Kisspeptin+ Virtual Conference International contribution

    Role(s):Planning, management, etc.

    Drs. Mike Lehman and Waljit Dhillo  2020.12 - 2021.4

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    Type:Academic society, research group, etc. 

  5. Asian-Australasian Journal of Animal Sciences International contribution

    Role(s):Peer review

    Dr. Jong K Ha  2020.4

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    Type:Peer review 

  6. 東海畜産学会評議員

    Role(s):Planning, management, etc.

    東海畜産学会  2020.4

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    Type:Academic society, research group, etc. 

  7. 日本繁殖生物学会理事 International contribution

    Role(s):Planning, management, etc.

    日本繁殖生物学会  2019.10

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    Type:Academic society, research group, etc. 

  8. 日本神経内分泌学会評議員 International contribution

    Role(s):Planning, management, etc.

    日本神経内分泌学会  2016

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    Type:Academic society, research group, etc. 

  9. 日本下垂体研究会評議員 International contribution

    Role(s):Planning, management, etc.

    日本下垂体研究会  2015

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    Type:Academic society, research group, etc. 

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