Updated on 2022/04/12

写真a

 
MATSUSHIMA, Miyoko
 
Organization
Graduate School of Medicine Lecturer
Graduate School
Graduate School of Medicine
Undergraduate School
School of Health Sciences
Title
Lecturer
Contact information
メールアドレス

Degree 1

  1. 博士(医療技術学) ( 2007.3   名古屋大学 ) 

Research Areas 2

  1. Life Science / Immunology

  2. Others / Others  / Pathological Examination Studies

Research History 2

  1. Nagoya University

    2010.4

  2. 名古屋大学大学院工学研究科 研究員

    2007.4 - 2007.11

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    Country:Japan

Education 3

  1. Nagoya University   Graduate School, Division of Medical Sciences   Program in Radiological and Medical Laboratory Sciences

    2004.4 - 2007.3

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    Country: Japan

  2. Nagoya University   Graduate School, Division of Medical Sciences   Program in Radiological and Medical Laboratory Sciences

    2002.4 - 2004.3

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    Country: Japan

  3. Nagoya University   Faculty of Medicine

    1998.4 - 2002.3

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    Country: Japan

Professional Memberships 6

  1. Japanese Sciety of Immunology

  2. Japanese Society of Allergology

  3. Japanese Society of Occupational Allergy

  4. The Pharmaceutical Society of Japan

  5. 日本食品免疫学会

  6. 日本薬理学会

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Papers 52

  1. Observation of Fine Lung Structure by Ultrahigh-Resolution Optical Coherence Tomography Using 800, 1060, and 1300nm Supercontinua Reviewed

    Ishida S, Nishizawa N, Kitatsuji M, Ohshima H, Hasegawa Y, Matsushima M, Kawabe T.

    Jpn. J. Appl. Phys   Vol. 51   page: 047001   2012.3

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    Language:English   Publishing type:Research paper (scientific journal)  

  2. Attenuation of TGF-beta-Stimulated Collagen Production in Fibroblasts by Quercetin-Induced HO-1. Reviewed

    Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y, Kawabe T.

    Am J Respir Cell Mol Biol   Vol. 44 ( 5 ) page: 614-620   2011.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 21216973

  3. Comparison of salivary cortisol, heart rate, and oxygen saturation between early skin-to-skin contact with different initiation and duration times in healthy, full-term infants Reviewed

    Takahashi Y, Tamakoshi K, Matsushima M, Kawabe T.

    Early Hum. Dev   Vol. 87 ( 3 ) page: 151-157   2011.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 21220191

    DOI: 10.1016/j.earlhumdev.2010.11.012

  4. Characteristics of an optimized catheter-type thermal flow sensor for measuring reciprocating airflows in bronchial pathways Reviewed

    Shikida M, Yokota T, Kawabe , Funaki T, Matsushima M, Iwai S, Matsunaga N, Sato K

    Micromech. Microen   Vol. 20 ( 12 ) page: 1-11   2010.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    We optimized a catheter-type thermal flow sensor to measure the reciprocating airflows in
    bronchial pathways. The electrical wiring in the outer tube was extracted to keep the symmetry
    of the temperature distribution on the heaters. First, a flexible sensor was fabricated on
    polyimide film with photolithography, and then the enameled wires were bonded to the contact
    pads on the film with anisotropic conductive film. The film sensor was finally assembled with
    a catheter configuration that had a diameter of 1.8 mm by applying a heat shrinkable tube. We
    experimentally confirmed that the sensor outputs under both forward and reverse flow
    conditions had the same output characteristics when a design with symmetrical heating
    elements was applied. The sensor outputs we obtained at a reciprocating flow frequency
    ranging from 1 to 3 Hz almost coincided, and they also fit that obtained under unidirectional
    airflow conditions. Finally, the aspirated- and inspired-air characteristics in the air passages of
    small laboratory animals (rats and mice) were measured. Due to our development of a flexible
    method of electrical wiring, we could try a new approach to intubation measurements in which
    the sensor was inserted into the air passage from the mouth with a fiberscope, and we
    confirmed that the sensor we developed was able to directly measure the breathing
    characteristics in air passages. Implanted measurements were also attempted in this study.
    (Some figures in this article are in colour only in the electronic version)

    DOI: 10.1088/0960-1317/20/12/125030

  5. Ghrelin and obestatin promote the allergic action in rat peritoneal mast cells as basic secretagogues Reviewed

    Hirayama T, Kawabe T, Matsushima M, Nishimura Y, Kobe Y, Ota Y, Baba K, Takagi K

    Peptides   Vol. 31 ( 11 ) page: 2109-2113   2010.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 20691233

  6. *Heme Oxygenase-1 Mediates the Anti-allergic Actions of Quercetin in Rodent Mast Cells Reviewed

    Matsushima M., Takagi K., Ogawa M., Hirose E., Ota Y., Abe F., Baba K., Hasegawa T., Hasegawa Y., Kawabe T.

    Inflammation Research   Vol. 58 ( 10 ) page: 705-715   2009.10

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 19390785

    DOI: 10.1007/s00011-009-0039-1

  7. Peptide array-based analysis of the specific IgE and IgG4 in cow's milk allergens and its use in allergy evaluation Reviewed

    Matsumoto N, Okochi M, Matsushima M, Kato R, Takase T, Yoshida Y, Kawase M, Isobe KI, Kawabe T, Honda H.

    Peptides   Vol. 30 ( 10 ) page: 1840-1847   2009.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 19619602

    DOI: 10.1016/j.peptides.2009.07.005

  8. Hemoglobin induces the expression of indoleamine 2,3-dioxygenase in dendritic cells through the activation of PI3K, PKC, and NF-kappaB and the generation of reactive oxygen species Reviewed

    Ogasawara N., Oguro T., Sakabe T., Matsushima M., Takikawa O., Isobe KI., Nagase F.

    J. Cell. Biochem.   Vol. 108 ( 3 ) page: 716-725   2009.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 19693771

    DOI: 10.1002/jcb.22308

  9. Involvement of Heme Oxygenase-1 in Kaempferol-induced Anti-allergic Actions in RBL-2H3 Cells Reviewed

    Matsushima M., Hirose E., Takagi K., Ota Y., Ishigami K., Hirayama T., Hayashi Y., Nakamura T., Hashimoto N., Imaizumi K., Baba K., Hasegawa Y., Kawabe T.

    Inflammation   Vol. 32 ( 2 ) page: 99-108   2009.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 19214725

    DOI: 10.1007/s10753-009-9108-4

  10. Inhibition of Degranulation by Myricetin-induced Heme Oxygenase-1 in Mast Cells Reviewed

    Ota Y., Matsushima M., Ogawa M., Hirose E., Hirayama T., Yuasa E., Yabuta K., Baba K., Hasegawa Y., Takagi K., Kawabe T

    Occupational and Environmental Allergy   Vol. 16 ( 2 ) page: 61-73   2009.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    Myricetin is one of the flavonoids with a variety of cytoprotective and immuno-modulatory functions. It provides their cytoprotective actions via activation of specific transcriptional factors and upregulation of endogenous defensive pathways. Although myricetin is also known to inhibit degranulation from mast cells, its mechanism is poorly understood. In this study, we investigated the involvement of heme oxygenase-1 (HO-1) induced by myricetin in degranulation of rat basophilic leukemia (RBL-2H3) cells. Our results demonstrated upregulation of heme oxygenase activity after short exposure to myricetin, followed by the induction of HO-1 expression in protein levels after long exposure to myricetin. The HO-1 inhibitor, SnPP, inhibited suppression of degranulation by myricetin from RBL-2H3 cells. Nuclear factor erythroid-2 related factor 2 (Nrf2) was translocated to nucleus by myricetin. These findings suggest that myricetin exerts anti-allergic actions via activation of HO-1-Nrf2 pathway. This study may well lead to promising new therapeutic strategies by flavonoid-HO-1 pathway in allergic inflammation.

  11. Development of peptide arrays for detection of IgE-binding epitopes in cow's milk allergens Reviewed

    Matsumoto N., Okochi M., Matsushima M., Ogawa A., Takase T., Yohida Y., Kawase M., Isobe K., Kawabe T., Honda H.

    Journal of Bioscience and Bioengineering   Vol. 107 ( 3 ) page: 324-330   2009.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 19269601

    DOI: 10.1016/j.jbiosc.2008.10.014

  12. Xenin and xenopsin induce histamine release from rat peritoneal mast cells Reviewed

    Matsushima M., Kitaichi k., Kawabe T., Suzuki R., Baba K., Hasegawa T., Takagi K.

    Occupational and Environmental Allergy   Vol. 14 ( 2 ) page: 60-67   2007.4

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    Xenin is a 25-amino acid peptide that was identified in human gastric mucosa during a search for a human counterpart of xenopsin, a 8-amino acid peptide, originally found in the skin of xenopus laevis. Xenin is also structurally related to the ileal and hypothalamic 13-amino acid peptide, neurotensin. The common amino acids on C-terminus that xenin, xenopsin and neurotensin share determine biological activities, such as contractions of the gastrointestinal tract and stimulation of pancreatic exocrine secretion. However, little is known about the effects of xenin and xenopsin on host immune systems. Thus we conducted a series of in vitro experiments with rat peritoneal mast cells to determine whether xenin or xenopsin has a histamine-releasing effect on mast cells. Xenin (10-8 to 10-5 M) induced histamine release in a dose-dependent manner. Xenopsin also induced histamine release from rat peritoneal mast cells. Xenin-induced (10-6 M) histamine release was inhibited by adding extracellular Ca2+ (0.5 to 2 mM) and benzalkonium chloride (1 to 5 microM), a selective inhibitor of Gi type G proteins. Histamine release induced by xenopsin-induced (10-4 M) histamine release also was inhibited by adding extracellular Ca2+ (0.5 to 2 mM) and benzalkonium chloride (1 to 5 microM). These results suggest that xenin and xenopsin induced histamine release in a fashion involving extracellular Ca2+- and Gi-dependent pathway similar to other endogenous peptides that induce histamine release and might play a role at the site of inflammation and /or immune response.

  13. Increased plasma concentration and brain penetration of methamphetamine in behaviorally sensitized rats Reviewed

    Kitaichi K., Morishita Y., Doi Y., Ueyama J., Matsushima M., Takagi K., Hasegawa T.

    Eur J Pharmacol   Vol. 464   page: 39-48   2003.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 12600693

    DOI: 10.1016/S0014-2999(03)01321-9

  14. The mRNA expression of calcitonin receptor-like receptor/receptor activity modifying proteins in rat peritoneal mast cells Reviewed

    Matsushima M., Kitaichi K., Tatsumi Y., Hasegawa T., Takagi K.

    Eur J Pharmacol   Vol. 464   page: 111-114   2003.3

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 12620502

    DOI: 10.1016/S0014-2999(03)01420-1

  15. Platelet factor 4 fragment induces histamine release from rat peritoneal mast cells Reviewed

    Suzuki R., Kimura T., Kitaichi K., Tatsumi Y., Matsushima M., Shibata E., Zhao Y. L., Baba K., Hasegawa T., Takagi K.

    Peptides   Vol. 23   page: 1713-1717   2002.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 12383857

    DOI: 10.1016/S0196-9781(02)00143-2

  16. Induction of histamine release from rat peritoneal mast cells by histatins Reviewed

    Yoshida M., Kimura T., Kitaichi K., Suzuki R., Baba K., Matsushima M., Tatsumi Y., Shibata E., Takagi K., Hasegawa T., Takagi K.

    Biol Pharm Bull   Vol. 24   page: 1267-1270   2001.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 11725961

    DOI: 10.1248/bpb.24.1267

  17. Quercetin protects against pulmonary oxidant stress via heme oxygenase-1 induction in lung epithelial cells Reviewed

    Hayashi Y, Matsushima M, Nakamura T, Shibasaki M, Hashimoto N, Imaizumi K, Shimokata K, Hasegawa Y, Kawabe T.

    Biochem Biophys Res Commun   Vol. 417 ( 1 ) page: 169-174   2012.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 22138401

  18. Involvement of heme oxygenase-1 in suppression of T cell activation by quercetin Reviewed International journal

    Sugiyama Tomoshi, Matsushima Miyoko, Ohdachi Tomoko, Hashimoto Naozumi, Hasegawa Yoshinori, Yokoi Kohei, Kawabe Tsutomu

    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY   Vol. 42 ( 4 ) page: 295 - 305   2020.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1080/08923973.2020.1759623

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  19. Modulation of immunological activity on macrophages induced by diazinon Reviewed International journal

    Ogasawara Nanako, Matsushima Miyoko, Kawamura Nami, Atsumi Kazuko, Yamaguchi Takehiro, Ochi Haruka, Kusatsugu Yuto, Oyabu Sayaka, Hashimoto Naozumi, Hasegawa Yoshinori, Ueyama Jun, Kawabe Tsutomu

    TOXICOLOGY   Vol. 379   page: 22 - 30   2017.3

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    DOI: 10.1016/j.tox.2017.01.014

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  20. Resistance to mutant KRAS<sup>V12</sup>-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line. Reviewed International coauthorship

    Muraki N, Yamada M, Doki H, Nakai R, Komeda K, Goto D, Kawabe N, Matsuoka K, Matsushima M, Kawabe T, Tanaka I, Morise M, Shay JW, Minna JD, Sato M

      Vol. 414 ( 1 ) page: 113053   2022.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.yexcr.2022.113053

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  21. Advancements in MEMS technology for medical applications: microneedles and miniaturized sensors Reviewed

    Shikida Mitsuhiro, Hasegawa Yoshihiro, Farisi Muhammad Salman Al, Matsushima Miyoko, Kawabe Tsutomu

      Vol. 61 ( SA )   2022.1

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    DOI: 10.35848/1347-4065/ac305d

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  22. Miniaturization of Respiratory Measurement System in Artificial Ventilator for Small Animal Experiments to Reduce Dead Space and Its Application to Lung Elasticity Evaluation

    Yoshida Homare, Hasegawa Yoshihiro, Matsushima Miyoko, Sugiyama Tomoshi, Kawabe Tsutomu, Shikida Mitsuhiro

    SENSORS   Vol. 21 ( 15 )   2021.8

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  23. Micro-machined stent flow sensor for detecting breathing and heartbeat from airflow in airway of rat Reviewed International journal

    Noma Hayato, Hasegawa Yoshihiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    JOURNAL OF MICROMECHANICS AND MICROENGINEERING   Vol. 31 ( 2 )   2021.2

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    DOI: 10.1088/1361-6439/abd07a

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  24. Development of sensor-probe system with function of measuring flow and pressure for evaluating breathing property at airway in lungs Reviewed International journal

    Kawamoto Yuji, Maeda Yoshifumi, Hasegawa Yoshihiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS     2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-020-05201-0

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  25. Catheter sensor system for in-situ breathing and optical imaging measurements at airway in inside of lung Reviewed International journal

    Maeda Y., Okihara C., Hasegawa Y., Taniguchi K., Matsushima M., Sugiyama T., Kawabe T., Shikida M.

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 26 ( 12 ) page: 3705 - 3713   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-020-04843-4

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  26. Development of micromachined flow sensor for drip infusion system Reviewed International journal

    Shimohira Chihiro, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 26 ( 12 ) page: 3677 - 3683   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-020-04839-0

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  27. Micro-machined respiratory monitoring system development for artificial ventilator in animal experiment Reviewed International journal

    Yoshida Homare, Hasegawa Yoshihiro, Matsushima Miyoko, Sugiyama Tomoshi, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 26 ( 12 ) page: 3715 - 3724   2020.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-020-04844-3

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  28. Energy-less respiration monitoring device using thermo-sensitive film Reviewed International journal

    Maeda Yoshihumi, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 26 ( 2 ) page: 489 - 497   2020.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-019-04482-4

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  29. Body temperature measurement based on breathing airflow for continuous monitoring of patient body condition during large scale disasters Reviewed International journal

    Fujinori Tomohiro, Hasegawa Yoshihiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 25 ( 11 ) page: 4313 - 4321   2019.11

  30. Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research.

    Ohno T, Miyasaka Y, Kuga M, Ushida K, Matsushima M, Kawabe T, Kikkawa Y, Mizuno M, Takahashi M

    Experimental animals   Vol. 68 ( 3 ) page: 243 - 255   2019.8

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  31. A micro-machined flow sensor formed on copper on a polyimide substrate and its application to respiration measurement Reviewed International journal

    Kato Ayami, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    JAPANESE JOURNAL OF APPLIED PHYSICS   Vol. 58   2019.6

  32. Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging Reviewed International journal

    NISHIZAWA Norihiko, KAWAGOE Hiroyuki, YAMANAKA Masahito, MATSUSHIMA Miyoko, MORI Kensaku, KAWABE Tsutomu

    IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS   Vol. 25 ( 1 )   2019

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1109/JSTQE.2018.2854595

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  33. 口元気流計測による乳幼児の呼吸心拍一括評価を目指した気管内挿管チューブ実装型流量センサシステムに関する研究 Reviewed

    光成勇樹, 長谷川義大, 谷口和弘, 松島充代子, 川部勤, 式田光宏

    電気学会論文誌E(センサ・マイクロマシン部門誌)   Vol. 139 ( 7 ) page: 186 - 194   2019

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1541/ieejsmas.139.186

  34. 口元気流計測による乳幼児の呼吸心拍一括評価を目指した気管内挿管チューブ実装型流量センサシステムに関する研究 Reviewed

    光成勇樹, 長谷川義大, 谷口和弘, 松島充代子, 川部勤, 式田光宏

    電気学会論文誌E(センサ・マイクロマシン部門誌)   Vol. 139 ( 7 ) page: 186 - 194   2019

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1541/ieejsmas.139.186

  35. Analysis of measurement conditions for detecting change in vital signs with catheter flow sensor Reviewed

    Hasegawa Y., Mitsunari Y., Kawaoka H., Matsushima M., Kawabe T., Shikida M.

    JOURNAL OF MICROMECHANICS AND MICROENGINEERING   Vol. 28 ( 10 )   2018.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1088/1361-6439/aad303

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  36. Catheter type thermal flow sensor with small footprint for measuring breathing function Reviewed International journal

    Hasegawa Y., Kawaoka H., Mitsunari Y., Matsushima M., Kawabe T., Shikida M.

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 24 ( 8 ) page: 3455 - 3465   2018.8

  37. Development of tube flow sensor by using film transfer technology and its application to in situ breathing and surface image evaluation in airways Reviewed International journal

    Okihara Chiaki, Hasegawa Yoshihiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS   Vol. 24 ( 8 ) page: 3417 - 3424   2018.8

  38. Obstetric factors associated with salivary cortisol levels of healthy full-term infants immediately after birth Reviewed International journal

    Takahashi Y., Matsushima M., Nishida T., Tanabe K., Kawabe T., Tamakoshi K.

    CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY   Vol. 45 ( 6 ) page: 828 - 832   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.12891/ceog4088.2018

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  39. Characterization of basket-forceps-type micro-flow-sensor for breathing measurements in small airway Reviewed International journal

    HARADA Naoaki, HASEGAWA Yoshihiro, ONO Ryota, MATSUSHIMA Miyoko, KAWABE Tsutomu, SHIKIDA Mitsuhiro

    Microsystem Technologies   Vol. 23 ( 12 ) page: 5397 - 5406   2017.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-016-3265-9

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  40. Respiration and heartbeat signal detection from airflow at airway in rat by catheter flow sensor with tmeparature compensation function Reviewed International journal

    HASEGAWA Yoshihiro, KAWAOKA Hidenori, YAMADA Takayuki, MATSUSHIMA Miyoko, KAWABE Tsutomu, SHIKIDA Mitsuhiro

    Journal of Micromechanics and Microengineering   Vol. 27 ( 12 )   2017.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1088/1361-6439/aa9595

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  41. Heartbeat signal detection from analysis of airflow in rat airway under different depths of anesthesia conditions Reviewed International journal

    KAWAOKA Hidenori, YAMADA Takayuki, MATSUSHIMA Miyoko, KAWABE Tsutomu, HASEGAWA Yoshihiro, SHIKIDA Mitsuhiro

    IEEE Sensors Journal   Vol. 17 ( 14 ) page: 4369 - 4377   2017.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1109/JSEN.2017.2707594

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  42. Development of implantable catheter flow sensor into inside of bronchi for laboratory animal Reviewed International journal

    SHIKIDA Mitsuhiro, MATSUYAMA Takuya, YAMADA Takayuki, MATSUSHIMA Miyoko, KAWABE Tsutomu

    Microsystem Technologies   Vol. 23 ( 1 ) page: 175 - 185   2017.1

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    DOI: 10.1007/s00542-015-2663-8

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  43. Modulation of immunological activity on macrophages induced by diazinon Reviewed

    OGASAWARA Nanako, MATSUSHIMA Miyoko, KAWAMURA Nami, ATSUMI Kazuko, YAMAGUCHI Takehiro, OCHI Haruka, KUSATSUGU Yuto, OYABU Sayaka, HASHIMOTO Naozumi, HASEGAWA Yoshinori, UEYAMA Jun, KAWABE Tsutomu

    Toxicology   Vol. 379   page: 22-30   2017

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    DOI: 10.1016/j.tox.2017.01.014.

  44. The suppressive effect of quercetin on Toll-like receptor 7-mediated activation in alveolar macrophages. Reviewed

    YASUI Masahiro, MATSUSHIMA Miyoko, OMURA Aya, MORI Kanae, OGASAWARA Nanako, KODERA Yuka, SHIGA Marika, ITO Komei, KOJIMA Seiji, KAWABE Tsutomu

    Pharmacology   Vol. 96 ( 5-6 ) page: 201-209   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1159/000438993

  45. Design and development of a suitable adsorbent to capture theophylline for non-invasive therapeutic drug monitoring with exhaled breath. Reviewed

    YAMAMOTO Atsushi, HIOKI Sayaka, TANADA Chihiro, MIWA Toshio, INOUE Yoshinori, YAMAMOTO Ryohei, MATSUSHIMA Miyoko, KAWABE Tsutomu

    Anal. Methods   Vol. 7   page: 423-427   2014.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/C4AY02243B

  46. Protective effects of intratracheally administered quercetin on lipopolysaccharide-induced acute lung injury. Reviewed

    TAKASHIMA Koji, MATSUSHIMA Miyoko, HASHIMOTO Katsunori, NOSE Haruka, SATO Mitsuo, HASHIMOTO Naozumi, HASEGAWA Yoshinori, KAWABE Tsutomu.

    Respir Res.   Vol. 15 ( 1 ) page: 150   2014.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s12931-014-0150-x

  47. Catheter flow sensor with temperature compensation for tracheal intubation tube system. Reviewed

    Shikida M, Yoshikawa K, Matsuyama T, Yamazaki Y, Matsushima M, Kawabe T.

    Sensors and Actuators A: Physical   Vol. 215   page: 155-160   2014.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.sna.2013.08.004

  48. 呼気吸気計測を目的とした自己温度補償型カテーテル流量センサの開発 Reviewed

    松山拓矢、山﨑雄大、松島充代子、川部 勤、式田光宏

    電気学会論文誌E(センサ・マイクロマシン部門誌)   Vol. 134 ( 6 ) page: 126-131   2014

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1541/ieejsmas.134.126

  49. Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice. Reviewed

    Ohno T, Okamoto M, Hara T, Hashimoto N, Imaizumi K, Matsushima M, Nishimura M, Shimokata K, Hasegawa Y, Kawabe T.

    Immunogenetics   Vol. 65 ( 1 ) page: 17-24   2013.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 23081743

  50. Micromachined catheter flow sensor and its applications in breathing measurements in animal experiments. Reviewed

    Shikida M, Shikano T, Matsuyama T, Yamazaki Y, Matsushima M, Kawabe T.

    Microsyst Technol.   Vol. 20 ( 3 ) page: 505-513   2013.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00542-013-1855-3

  51. ミルクタンパク質全網羅ペプチドアレイを用いたIgG結合ペプチドの探索 Reviewed

    片山 真、杉田智哉、加藤竜司、大河内美奈、松島充代子、川部 勤、高瀬智和、吉田安子、川瀬三雄、本多裕之

    化学工学論文集   Vol. 37 ( 6 ) page: 546-550   2011.9

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  52. CD40/CD40 ligand interactions in immune responses and pulmonary immunity Reviewed

    Kawabe T, Matsushima M, Hashimoto N, Imaizumi K, Hasegawa Y.

    Nagoya J Med Sci   Vol. 73 ( 3-4 ) page: 69-78   2011.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed ID: 21928689

▼display all

Books 1

  1. 覚せい剤依存と麻薬依存

    北市清幸, 森下友喜, 土井悠子, 上山 純, 松島充代子, 巽 康彰, 高木健次, 柴田英治, 高木健三, 長谷川高明.( Role: Sole author)

    東北大学出版会  2004 

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    Language:Japanese

Presentations 244

  1. Quercetin-induced cytoprotective action by modification of cell membrane International conference

    Matsushima M., Nose H., Kusatsugu Y., Tanaka K., Takekoshi M., Tsubosaki Y., Inoue G., Iwaki K., Hayashi Y., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  2. Effects of neonicotinoid and organophosphorus insecticides on macrophage functions. International conference

    SASOU Kanako, MATSUSHIMA Miyoko, OGASAWARA Nanako, OHDACHI Tomoko, ATSUMI Kazuko, TANAKA Kyohka, SUGIYAMA Tomoshi, UEYAMA Jun, HASHIMOTO Naozumi, KAWABE Tsutomu.

    18th World Congress of Basic and Clinical Pharmacology 

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    Event date: 2018.7

    Language:English   Presentation type:Poster presentation  

  3. Effects of diazinon on mast cell activation International conference

    TANAKA Kyohka, MATSUSHIMA Miyoko, ATSUMI Kazuko, SASOU Kanako, SUGIYAMA Tomoshi, OHDACHI Tomoko, UEYAMA Jun, HASHIMOTO Naozumi, KAWABE Tsutomu

    18th World Congress of Basic and Clinical Pharmacology 

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    Event date: 2018.7

    Language:English   Presentation type:Poster presentation  

  4. Involvement of localization changes of caveolin-1 in Nrf2 activation induced by quercetin International conference

    Matsushima Miyoko, Kusatsugu Yuto, Ochi Haruka, Oyabu Savaka, Atsumi Kazuko, Ogasawara Nanako, Kawabe Tsutomu

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    Event date: 2017.3

    Language:Japanese   Presentation type:Poster presentation  

  5. Analysis of efferocytosis on type 2-skewed immune responses in NC/Nga mice

    Teppei Yamashita, Miyoko Matsushima, Goki Inoue, Ko Iwaki, Yuki Hayashi, Moeko Ohara, Hikaru Tsuzuki, Tsutomu Kawabe.

    2021.12.10 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  6. Involvement of p62 on Activation of Heme Oxygenase-1 Induced by Quercetin

    Yuki Hayashi, Miyoko Matsushima, Goki Inoue, Ko Iwaki, Teppei Yamashita, Moeko Ohara, Hikaru Tsuzuki, Tsutomu Kawabe

    2021.12.8 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  7. Effects of localization changes of caveolin-1 on cellular function induced by quercetin

    Hikaru Tsuzuki, Miyoko Matsushima, Goki Inoue, Ko Iwaki, Yuki Hayashi, Teppei Yamashita, Moeko Ohara, Tsutomu Kawabe

    2021.12.8 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  8. Investigation of B-cell differentiation on atopic dermatitis model mice

    Moeko Ohara, Miyoko Matsushima, Hikaru Tsuzuki, Goki Inoue, Ko Iwaki, Yuki Hayashi, Teppei Yamashita, Tsutomu Kawabe

    2021.12.9 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  9. Attenuation of signal transduction induced by diazinon in RBL-2H3 cells

    Goki Inoue, Miyoko Matsushima, Ko Iwaki, Yuki Hayashi, Teppei Yamashita, Moeko Ohara, Hikaru Tsuzuki, Tsutomu Kawabe

    2021.12.9 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  10. Effects on function of macrophages by diazinon-modified metabolic status

    Ko Iwaki, Miyoko Matsushima, Goki Inoue, Yuki Hayashi, Teppei Yamashita, Moeko Ohara, Hikaru Tsuzuki, Tsutomu Kawabe

    2021.12.10 

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    Event date: 2021.12

    Language:English   Presentation type:Poster presentation  

  11. 呼吸の物理量情報をもとに評価する心肺機能 Invited

    川部 勤、松島充代子、長谷川 信、長谷川義大、式田光宏

    第 58 回日本臨床生理学会総会  2021.11.13 

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    Event date: 2021.11

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

  12. 肥満細胞の即時型および遅発型反応に対するダイアジノンの免疫修飾作用

    岩城 巧, 松島充代子, 坪﨑由夏, 小原萌恵子, 竹腰正広, 井上剛希, 川部 勤

    第51回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2020.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  13. Modulatory effects of diazinon on mast cell activation. International conference

    Miyoko Matsushima, Kazuko Atsumi, Moeko Ohara, Masahiro Takekoshi, Yuka Tsubosaki, Goki Inoue, Ko Iwaki, Yuki Hayashi, Teppei Yamashita, Tsutomu Kawabe.

    JSA/WAO XXVII World Allergy Congress (WAC 2020) conjoint with the APAPARI 2020 Congress.  

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    Event date: 2020.9

    Language:English   Presentation type:Poster presentation  

  14. 呼吸に伴い変化する物理量の解析から得られる生体情報の意義についての検討

    川部 勤, 松島充代子, 橋本直純, 佐藤光夫, 長谷川好規, 長谷川 信, 長谷川義大, 式田光宏

    第60回日本呼吸器学会学術講演会 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  15. 呼気分析を応用した非侵襲的治療薬物モニタリングシステムの検討

    川部 勤, 松島充代子, 橋本直純, 佐藤光夫, 長谷川好規, 山本良平, 山本 敦

    第60回日本呼吸器学会学術講演会 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Oral presentation (general)  

  16. DEVELOPMENT OF STENT FLOW SENSOR DEVICE EVALUATING BREATHING PROPERTY AT AIRWAY IN EXPERIMENTAL ANIMAL UNDER FREE MOVE CONDITION International conference

    Noma Hayato, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    2020 33RD IEEE INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS (MEMS 2020) 

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    Event date: 2020

    Language:English   Presentation type:Poster presentation  

  17. Wavelength dependence of ultrahigh resolution optical coherence tomography using supercontinuum International conference

    Nishizawa Norihiko, Yamanaka Masahito, Kawagoe Hiroyuki, Matsushima Miyoko, Mori Kensaku, Kawabe Tsutomu

    OPTICAL BIOPSY XVIII: TOWARD REAL-TIME SPECTROSCOPIC IMAGING AND DIAGNOSIS 

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    Event date: 2020

    Language:English  

  18. The effects of widely-used neonicotinoid insecticides on macrophage function

    Yuka Tsubosaki, Miyoko Matsushima, Kyohka Tanaka, Masahiro Takekoshi, Tsutomu Kawabe.

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

  19. Analysis of B cell differentiation in NC/Nga mice

    Masahiro Takekoshi, Miyoko Matsushima, Kyohka Tanaka, Yuka Tsubosaki, Tsutomu Kawabe.

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

  20. 銅張積層板を用いた流路構造一体型 MEMS 流量センサの開発

    瀧川 流成, 長谷川 義大, 谷口 和弘, 松島 充代子, 川部 勤, 式田 光宏

    第36回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2019.11

    Language:Japanese  

  21. フレキシブル基板上での MEMS 流量センサと信号処理回路との一体化に関する研究

    加藤 絢美, 藤綱 伊織, 長谷川 義大, 谷口 和弘, 松島 充代子, 川部 勤、式田 光宏

    第36回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2019.11

    Language:Japanese  

  22. 点滴システムへの応用を目指したマイクロ流量センサの開発

    下平 千尋, 長谷川 義大, 谷口 和弘, 松島 充代子, 川部 勤, 式田 光宏

    第36回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2019.11

    Language:Japanese  

  23. 経気管支的に呼吸および光学画像計測を可能とするカテーテルセンサシステムに関する研究

    前田 佳史, 長谷川 義大, 谷口 和弘, 松島 充代子, 川部 勤, 式田 光宏

    第36回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2019.11

    Language:Japanese  

  24. 実験動物における気道内流量計測を目的としたステント型流量センサの開発

    野間 颯斗, 長谷川 義大, 谷口 和弘, 松島 充代子, 川部 勤, 式田 光宏 

    第36回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2019.11

    Language:Japanese  

  25. Effects of acetamiprid on Toll-like receptor 7-mediated inflammation International conference

    Hayashi Y., Matsushima M., Takekoshi M., Saso K., Tanaka K., Tsubosaki Y., Inoue G., Iwaki K., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  26. Development of Breathing Monitoring System for Artificial Ventilator in Animal Experiment. International conference

    H. Yoshida, Y. Hasegawa, K. Taniguchi, M. Matsushima, T. Kawabe, M. Shikida.

    32nd International Microprocesses and Nanotechnology Conference (MNC2019) 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  27. Suppressive effects of flavonoids on T cell activation International conference

    Tsubosaki Y., Matsushima M., Sugiyama T., Tanaka K., Takekoshi M., Inoue G., Iwaki K., Hayashi Y., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  28. Modification of allergic inflammation in murine model of allergic conjunctivitis without CD40 signal International conference

    Iwaki K., Matsushima M., Kawabe M., Mizutani M., Tsubosaki Y., Takekoshi M., Tanaka K., Inoue G., Hayashi Y., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  29. Lung inflammation is attenuated by intratracheal administration of quercetin International conference

    Inoue G., Matsushima M., Takashima K., Tanaka K., Takekoshi M., Tsubosaki Y., Iwaki K., Hayashi Y., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  30. Evaluation of IgM autoantibody in autoimmune hemolytic anemia International conference

    Takekoshi M., Matsushima M., Tanaka K., Inoue G., Tsubosaki Y., Iwaki K., Hayashi Y., Yamashita T., Kawabe T.

    IUIS2019 

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    Event date: 2019.10

    Language:English   Presentation type:Poster presentation  

  31. MICRO-MACHINEED CATHETER SENSOR SYSTEMATIZATION FOR IN-SITU BREATHING AND OPTICAL IMAGING MEASUREMENTS IN BRONCHUS REGION IN LUNG SYSTEM International conference

    Maeda Yoshifumi, Okihara Chiaki, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    Tech. Dig. of 45th International Conference on Micro & Nano Engineering (MNE2019) 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

  32. Flow sensor and stent integration for evaluating in-situ breathing property at airway in experimental animal. International conference

    H. Noma, Y. Hasegawa, K. Taniguchi, M. Matsushima, T. Kawabe, M. Shikida

    Tech. Dig. of 45th International Conference on Micro & Nano Engineering (MNE2019) 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

  33. Thermal flow sensor operated under 40 degrees Celsius for controlling small dosing rate in drip infusion system International conference

    C. Shimohira, Y. Hasegawa, K. Taniguchi, M. Matsushima, T. Kawabe, M. Shikida.

    Tech. Dig. of 45th International Conference on Micro & Nano Engineering (MNE2019) 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

  34. A thermal flow sensor and its signal processing circuit integration onto flexible copper on polyimide substrate. International conference

    A. Kato, Y. Hasegawa, K. Taniguchi, M. Matsushima, T. Kawabe, M. Shikida.

    Tech. Dig. of 45th International Conference on Micro & Nano Engineering (MNE2019) 

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

  35. The role of innate immunity on type 2 immune response in bronchial asthma. International conference

    TAKEKOSHI Masahiro, MATSUSHIMA Miyoko, YAMASHITA Teppei, INOUE Goki, IWAKI Ko, HAYASHI Yuki, TANAKA Kyohka, TSUBOSAKI Yuka, KAWABE Tsutomu

    28th Congress of Interasthma Japan North Asia 

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    Event date: 2019.9

    Language:English   Presentation type:Oral presentation (general)  

  36. 呼吸にもとづいた生体情報計測技術の開発

    LEE SEUNGHYEON, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    生体医工学シンポジウム2019 

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    Event date: 2019.9

    Language:Japanese  

  37. ラット呼気からの薬物排泄量と肺組織内薬物濃度との相関

    岩出真歩, 日下部純平, 中島花奈, 山本良平, 山本敦, 松島充代子, 川部 勤

    日本分析化学会 第68年会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

  38. MEMS技術を用いた動物用人工呼吸器計測評価システムの開発

    吉田誉, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    生体医工学シンポジウム2019 

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    Event date: 2019.9

    Language:Japanese  

  39. 自己免疫性溶血性貧血の発症における自己抗体のアイソタイプの意義

    竹腰正広, 松島充代子, 井上剛希, 田中杏佳, 坪崎由夏, 岩城 巧, 林 祐希, 山下哲平, 川部 勤

    第14回臨床検査学教育学会学術大会 

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    Event date: 2019.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  40. 環境物質としての農薬による健康被害についてのin vitro評価‐ネオニコチノイド系農薬の場合‐

    坪崎由夏, 松島充代子, 林 祐希, 竹腰正広, 田中杏佳、井上剛希, 岩城 巧, 山下哲平, 上山 純,川部 勤

    第14回臨床検査学教育学会学術大会 

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    Event date: 2019.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  41. アセタミプリドが気道系の免疫応答に及ぼす影響についての評価

    坪崎由夏, 松島充代子, 林 祐希, 竹腰正広, 田中杏佳、井上剛希, 岩城 巧, 山下哲平, 上山 純,川部 勤

    第50回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2019.7

    Language:Japanese   Presentation type:Oral presentation (general)  

  42. フラボノイドがT細胞のIL-2の産生および細胞増殖に及ぼす効果

    松島充代子, 川部 勤

    第68回日本アレルギー学会学術大会 

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    Event date: 2019.6

    Language:Japanese   Presentation type:Poster presentation  

  43. 気道内留置可能なステント型流量センサの開発

    野間颯斗, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    平成31年電気学会全国大会 

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    Event date: 2019.3

    Language:Japanese  

  44. 流路構造付きMEMS流量センサの開発

    瀧川流成, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    平成31年電気学会全国大会 

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    Event date: 2019.3

    Language:Japanese  

  45. 滴投与量計測用マイクロ流量センサの開発

    下平千尋, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    平成31年電気学会全国大会 

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    Event date: 2019.3

    Language:Japanese  

  46. 動物実験用人工呼吸器計測評価システムの開発

    吉田誉, 長谷川義大, 谷口和弘, 式田光宏, 松島充代子, 川部勤

    平成31年電気学会全国大会 

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    Event date: 2019.3

    Language:Japanese  

  47. INTEGRATION OF MEMS FLOW SENSOR, ELECTRICAL WIRING, AND TUBE STRUCTURE ONTO COPPER ON POLYIMIDE SUBSTRATE International conference

    Takigawa Ryusei, Hasegawa Yoshihiro, Taniguchi Kazuhiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    2019 20TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS & EUROSENSORS XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) 

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    Event date: 2019

    Language:English   Presentation type:Poster presentation  

  48. Modification of immune function by neonicotinoid and organophosphorus insecticides.

    Miyoko Matsushima, Kanako Sasou, Kyohka Tanaka, Tsutomu Kawabe.

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    Event date: 2018.12

    Language:English   Presentation type:Poster presentation  

  49. Diazinon-induced dysregulation of mast cell function

    Kyohka Tanaka, Miyoko Matsushima, Kanako Sasou, Tsutomu Kawabe.

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    Event date: 2018.12

    Language:English   Presentation type:Poster presentation  

  50. Micro-machined flow sensor formed on copper on polyimide substrate and its respiration measurement application. International conference

    A. Kato, Y. Hasegawa, K. Taniguchi, M. Mastushima, T. Kawabe, M. Shikida.

    31st International Microprocesses and Nanotechnology Conference (MNC2018) 

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    Event date: 2018.11

    Language:English   Presentation type:Poster presentation  

  51. Development of three layered tube type flow sensor for human respiration measurement

    Y. Mitsunari, S. Watanabe, Y. Hasegawa, M. Matsushima, T. Kawabe, M. Shikida.

    31st International Microprocesses and Nanotechnology Conference (MNC2018) 

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    Event date: 2018.11

    Language:English   Presentation type:Poster presentation  

  52. 光コヒーレンストモグラフィ(optical coherence tomography)を用いたイメージングと形態計測による肺組織の評価について

    川部 勤, 松島充代子, 西澤典彦

    第39回日本レーザー医学会総会 

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    Event date: 2018.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  53. 呼吸と体温の両計測が可能なMEMS流量センサの開発

    藤範知弘, 長谷川義大, 谷口和弘, 松島充代子, 川部勤, 式田光宏

    第35回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2018.10

    Language:Japanese  

  54. 乳幼児の呼吸心拍一括計測を目指した気管挿管チューブ実装型MEMS流量センサシステムに関する研究

    光成勇樹, 長谷川義大, 松島充代子, 川部 勤, 式田光宏

    第35回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2018.10

    Language:Japanese  

  55. 銅張積層板を用いた温度補償機能搭載型MEMS呼吸センサの開発

    加藤絢美, 長谷川義大, 谷口和弘, 松島充代子, 川部勤, 式田光宏

    第35回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2018.10

    Language:Japanese  

  56. 感温フィルムを用いた簡易的呼吸検知デバイスの開発

    前田佳史, 長谷川義大, 谷口和弘, 松島充代子, 川部勤, 式田光宏

    第35回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2018.10

    Language:Japanese  

  57. 農薬によって修飾される免疫応答についての基礎的検討

    佐宗香奈子, 松島充代子, 渥美和子, 田中杏佳, 上山 純, 川部 勤

    第13回臨床検査学教育学会学術大会 

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    Event date: 2018.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  58. 肥満細胞の活性化に及ぼすダイアジノンの効果についての基礎的検討

    佐宗香奈子, 松島充代子, 渥美和子, 田中杏佳, 杉山燈人, 大立知子, 上山 純, 川部 勤

    第49回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2018.7

    Language:Japanese   Presentation type:Oral presentation (general)  

  59. Breathing monitoring by energy-less respiration sensor based on thermo-sensitive film. International conference

    Y. Maeda, Y. Hasegawa, K. Taniguchi, M. Matsushima, T. Kawabe, M. Shikida.

    Tech. Dig. of Asia-Pacific Conference on Transducers and Micro-Nano Technology 

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    Event date: 2018.6

    Language:English   Presentation type:Poster presentation  

  60. MEMS Flow Sensor Integration into Tracheal Tube Device and its Application to Respiration and Heartbeat Signal Detection in Infant. International conference

    Y. Mitsunari, Y. Hasegawa, M. Matsushima, T. Kawabe, M. Shikida.

    Tech. Dig. of Asia-Pacific Conference on Transducers and Micro-Nano Technology 

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    Event date: 2018.6

    Language:English   Presentation type:Poster presentation  

  61. 農薬が肥満細胞の活性化に与える影響についての基礎的検討

    松島充代子, 川部 勤

    第67回日本アレルギー学会学術大会 

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    Event date: 2018.6

    Language:Japanese   Presentation type:Poster presentation  

  62. 呼気を使った TDM の可能性―ラット呼気量を補正 するための指標物質の探索

    日下部純平, 小西真菜香, 山本良平, 山本 敦, 松島充代子, 川部 勤

    日本薬学会第138回年会 

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    Event date: 2018.3

    Language:Japanese   Presentation type:Poster presentation  

  63. Deteriorated amount of IC capture without CD40 on B cells

    第46回日本免疫学会 

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    Event date: 2017.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台国際センター   Country:Japan  

  64. Analysis on signal pathway in pro-inflammatory response by diazinon

    第46回日本免疫学会 

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    Event date: 2017.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台国際センター   Country:Japan  

  65. 乳幼児の口元気流計測を目的とした熱式チューブ型マイクロ流量センサの開発

    光成勇樹、長谷川義大、松島充代子、川部 勤、式田光宏

    第34回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2017.10 - 2017.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:広島国際会議場   Country:Japan  

  66. 末梢気道におけるその場観察と呼吸量計測を可能とする光ファイバースコープ搭載型流量センサの開発

    沖原千明、長谷川 義大、松島充代子、川部 勤、式田 光宏

    第34回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2017.10 - 2017.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:広島国際会議場   Country:Japan  

  67. 気流検出機能付気管チューブシステムとそれによるその場呼吸計測法に関する研究

    渡辺 瞬、長谷川義大、松島充代子、川部 勤、式田光宏

    第34回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2017.10 - 2017.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:広島国際会議場   Country:Japan  

  68. 経気管支的に肺機能計測が可能な気管支径対応カテーテル型流量センサの開発

    藤範知弘、長谷川義大、松島充代子、川部 勤、式田光宏

    第34回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2017.10 - 2017.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:広島国際会議場   Country:Japan  

  69. Micromachined tube type thermal flow sensor for adult-sized tracheal intubation tube International conference

    Eurosensors2017 

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    Event date: 2017.9

    Language:English   Presentation type:Poster presentation  

    Venue:UICP Conference Center   Country:France  

  70. Development of small-footprint thermal sensor detecting airflow at mouth in baby International conference

    Eurosensors2017 

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    Event date: 2017.9

    Language:English   Presentation type:Poster presentation  

    Venue:UICP Conference Center   Country:France  

  71. Development of catheter flow sensor for breathing measurements at different levels of tracheobronchial airway International conference

    Eurosensors2017 

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    Event date: 2017.9

    Language:English   Presentation type:Poster presentation  

    Venue:UICP Conference Center   Country:France  

  72. ダイアジノンは骨髄由来マクロファージを活性化させ、免疫応答を修飾する

    渥美和子、松島充代子、小笠原名奈子、佐宗香奈子、上山 純、川部 勤

    第48回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2017.6 - 2017.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:AOSSA   Country:Japan  

  73. Integration of flow sensor and optical fiberscope for in-situ breathing and surface image evaluations in small airway International conference

    19th International Conference on Solid-State Sensors, Actuators and Microsystems 

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    Event date: 2017.6

    Language:English   Presentation type:Poster presentation  

    Venue:Kaohsiung Exhibition Center   Country:Taiwan, Province of China  

  74. 農薬が免疫機能に与える影響についての基礎的検討

    松島充代子、川部 勤

    第66回日本アレルギー学会学術大会 

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    Event date: 2017.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京国際フォーラム   Country:Japan  

  75. 呼気エアロゾルを代替血液とした TDM は可能か?

    谷畑壮磨、山本良平、山本 敦、東海林秀典、加藤祐史、下内章人、松島充代子、川部 勤

    日本薬学会第137回年会 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:仙台国際センター   Country:Japan  

  76. 分子標的薬のための選択的吸着剤開発

    大澤磨未、高井里奈、山本良平、山本 敦、松島充代子、川部 勤

    日本薬学会第137回年会 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:仙台国際センター   Country:Japan  

  77. ケルセチンによるNrf2活性化におけるcaveolin-1の局在変化の関与

    第90回日本薬理学会年会 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:長崎ブリックホール、長崎新聞文化ホール アストピア   Country:Japan  

  78. INTEGRATION OF FLOW SENSOR AND OPTICAL FIBERSCOPE FOR IN-SITU BREATHING AND SURFACE IMAGE EVALUATIONS IN SMALL AIRWAY International conference

    Okihara Chiaki, Hasegawa Yoshihiro, Matsushima Miyoko, Kawabe Tsutomu, Shikida Mitsuhiro

    2017 19TH INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS (TRANSDUCERS) 

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    Event date: 2017

    Language:English   Presentation type:Poster presentation  

  79. The Induction of Macrophage Activation by Diazinon

    第45回日本免疫学会 

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    Event date: 2016.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:沖縄コンベンションセンター、ラグナガーデンホテル   Country:Japan  

  80. Somatic hypermutation is not altered without CD40 signaling in T-B interaction

    第45回日本免疫学会 

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    Event date: 2016.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:沖縄コンベンションセンター、ラグナガーデンホテル   Country:Japan  

  81. Effect of guide tube length on sensor output in inspired airflow measurement International conference

    29th International Microprocesses and Nanotechnology Conference 

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    Event date: 2016.11

    Language:English   Presentation type:Poster presentation  

    Venue:ANA Crowne Plaza Kyoto   Country:Japan  

  82. Breathing signal analysis of mouse during drug inhalation International conference

    29th International Microprocesses and Nanotechnology Conference 

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    Event date: 2016.11

    Language:English   Presentation type:Poster presentation  

    Venue:ANA Crowne Plaza Kyoto   Country:Japan  

  83. Measurement of heartbeat signals from airflow at mouth in rat by catheter flow sensor International conference

    IEEE Sensors 2016 

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    Event date: 2016.10 - 2016.11

    Language:English   Presentation type:Poster presentation  

    Venue:Caribe Royale All-Suite Hotel and Convention Center   Country:United States  

  84. Development of cylinder hollow structure with flow sensor by film transfer technology International conference

    IEEE Sensors 2016 

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    Event date: 2016.10 - 2016.11

    Language:English   Presentation type:Poster presentation  

    Venue:Caribe Royale All-Suite Hotel and Convention Center   Country:United States  

  85. 肺機能評価を目的としたバスケット鉗子搭載型MEMS流量センサの開発

    長谷川義大、原田直明、小野良太、松島充代子、川部 勤、式田光宏

    第33回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:平戸文化センター   Country:Japan  

  86. 心拍信号検出を目的とした温度補償機能付カテーテル型流量センサの開発

    河岡秀宜、山田貴之、松島充代子、川部 勤、長谷川義大、式田光宏

    第33回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:平戸文化センター   Country:Japan  

  87. 肺機能計測用カテーテル型流量センサの高速応答化に関する研究

    渡辺 瞬、長谷川義大、松島充代子、川部 勤、式田光宏

    第33回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:平戸文化センター   Country:Japan  

  88. 呼吸心拍測定を目指した温度補償機能付き熱式カテーテル型センサの開発

    光成勇樹、長谷川義大、松島充代子、川部 勤、式田光宏

    第39回日本生体医工学会中国四国支部大会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:徳島大学 常三島キャンパス   Country:Japan  

  89. マルチ計測モードが可能なMEMS流量センサの開発

    藤範知弘、長谷川義大、松島充代子、川部 勤、式田光宏

    第39回日本生体医工学会中国四国支部大会 

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    Event date: 2016.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:徳島大学 常三島キャンパス   Country:Japan  

  90. 生体防御機構の誘導を指標とした有害物質の評価法の探索

    大薮沙也果、松島充代子、草次裕人、小笠原名奈子、武村和哉、越智 悠、渥美和子、川部 勤

    第11回臨床検査学教育学会学術大会 

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    Event date: 2016.8 - 2016.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue: 神戸常磐大学   Country:Japan  

  91. 生体防御機構の誘導を指標とした有害物質の評価法の探索

    大薮沙也果、松島充代子、草次裕人、小笠原名奈子、武村和哉、越智 悠、渥美和子、川部 勤

    第11回臨床検査学教育学会学術大会 

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    Event date: 2016.8 - 2016.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神戸常磐大学   Country:Japan  

  92. Quercetin Suppressed Imiquimod-Induced Activation of Alveolar Macrophages International conference

    OYABU Sayaka, MATSUSHIMA Miyoko , OMURA Aya, OGASAWARA Nanako, OCHI Haruka, KUSATSUGU Yuto, ATSUMI Kazuko, TAKEMURA Kazuya, KAWABE Tsutomu

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  93. Critical Role of Selective Autophagy Adaptor Protein p62 in Quercetin-Induced Nrf2 Activation International conference

    KUSATSUGU Yuto, MATSUSHIMA Miyoko, OYABU Sayaka, OCHI Haruka, ATSUMI Kazuko, OGASAWARA Nanako, TAKEMURA Kazuya, KAWABE Tsutomu

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  94. Involvement of Caveolin-1 in Quercetin-Induced Nrf2 Activation International conference

    MATSUSHIMA Miyoko, KUSATSUGU Yuto, OYABU Sayaka, OCHI Haruka, ATSUMI Kazuko, OGASAWARA Nanako, TAKEMURA Kazuya, KAWABE Tsutomu

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  95. Involvement of CD40 in the Expression of Bcl6 International conference

    OCHI Haruka, MATSUSHIMA Miyoko, KODERA Yuka, KUSATSUGU Yuto, OYABU Sayaka, ATSUMI Kazuko, OGASAWARA Nanako, TAKEMURA Kazuya, KAWABE Tsutomu

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  96. Involvement of CD40 on Immune Cells in Response to Immune Complexes International conference

    ATSUMI Kazuko, MATSUSHIMA Miyoko, OGISO Hiroki, OCHI Haruka, KUSATSUGU Yuto, OYABU Sayaka, OGASAWARA Nanako, TAKEMURA Kazuya, KAWABE Tsutomu

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    Event date: 2016.8

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  97. Response time shortening in thermal catheter flow sensor International conference

    Asia-Pacific Conference on Transducers and Micro-Nano Technology 

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    Event date: 2016.7

    Language:English   Presentation type:Poster presentation  

    Venue:Kanazawa Bunka Hall   Country:Japan  

  98. 農薬の環境曝露が免疫機能に及ぼす影響についての基礎的検討

    渥美和子、松島充代子、小笠原名奈子、武村和也、越智 悠、草次裕人、大薮沙也果、上山 純、川部 勤

    第47回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:近畿大学11月ホール   Country:Japan  

  99. 農薬の環境曝露が免疫機能に及ぼす影響についての基礎的検討

    渥美和子、松島充代子、小笠原名奈子、武村和也、越智 悠、草次裕人、大薮沙也果、上山 純、川部 勤

    第47回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2016.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:近畿大学11月ホール   Country:Japan  

  100. 症状発現の推測を目論む血清IgEを用いたI型アレルギー検査法の検討

    松島充代子、川部 勤

    第65回日本アレルギー学会学術大会 

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    Event date: 2016.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京国際フォーラム   Country:Japan  

  101. 症状発現の推測を目論む血清IgEを用いたI型アレルギー検査法の検討

    松島充代子、川部 勤

    第65回日本アレルギー学会学術大会 

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    Event date: 2016.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京国際フォーラム   Country:Japan  

  102. 呼気を使った非侵襲的TDM-呼気エアロゾルの構造

    谷畑壮磨、山本良平、山本 敦、越智 悠、草次裕人、松島充代子、川部 勤

    第33回日本TDM学会・学術大会 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:栃木県総合文化センター   Country:Japan  

  103. Micro flow sensor integration onto basket forceps for pulmonary function evaluation International conference

    11th IEEE Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS) 

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    Event date: 2016.4

    Language:English   Presentation type:Poster presentation  

    Venue:Matsushima Bay and Sendai MEMS City   Country:Japan  

  104. Detection of kinetic heartbeat signals from airflow at mouth by catheter flow sensor with temperature compensation. International conference

    KAWAOKA Hidenori, YAMADA Takayuki, MATSUSHIMA Miyoko , KAWABE Tsutomu, HASEGAWA Yoshinori, SHIKIDA Mitsuhiro

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    Event date: 2016.1

    Language:English   Presentation type:Poster presentation  

    Country:China  

  105. 呼吸器系疾患の精密診断を目的としたバスケット鉗子実装型MEMSセンサの開発

    原田直明、小野良太、松島充代子、川部 勤、長谷川義大、式田光宏

    第38回日本生体医工学会中国四国支部大会 

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    Event date: 2015.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島市立大学   Country:Japan  

  106. 呼吸心拍検出を目的とした温度補償機能付MEMS流量センサの開発

    河岡秀宜、山田貴之、松島充代子、川部 勤、長谷川義大、式田光宏

    第38回日本生体医工学会中国四国支部大会 

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    Event date: 2015.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島市立大学   Country:Japan  

  107. The role of CD40 on immune responses against immune complex

    OGISO Hiroki, MATSUSHIMA Miyoko, OOMURA Aya, OCHI Haruka, KUSATSUGU Yuto, KAWABE Tsutomu

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    Event date: 2015.11

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  108. The involvement of autophagy on quercetin-induced Nrf2 activation

    KUSATSUGU Yuto, MATSUSHIMA Miyoko, OOMURA Aya, OGISO Hiroki, OCHI Haruka, KAWABE Tsutomu

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    Event date: 2015.11

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  109. Extraction of heartbeat signal from airflow at mouth by flow sensor International conference

    KAWAOKA Hidenori, YAMADA Takayuki, MATSUSHIMA Miyoko , KAWABE Tsutomu, HASEGAWA Yoshinori, SHIKIDA Mitsuhiro

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    Event date: 2015.11

    Language:English   Presentation type:Poster presentation  

    Country:Korea, Republic of  

  110. Responsible time shorting of flexible thermal flow sensor for medical applications International conference

    IMAEDA Kodai, SHIBATA Shunji, MATSUSHIMA Miyoko , KAWABE Tsutomu, SHIKIDA Mitsuhiro

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    Event date: 2015.11

    Language:English   Presentation type:Poster presentation  

    Country:Korea, Republic of  

  111. 多波長帯OCTイメージングによるラット肺組織の3次元解析

    安藤栄充,川越寛之,山中真仁,松島充代子,森 健策,川部 勤,西澤典彦

    日本光学会年次学術講演会Optics & Photonics Japan 2015 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:筑波大学東京キャンパス文京校舎   Country:Japan  

  112. MEMSカテーテル型流量センサを用いた呼吸心拍機能検出

    河岡秀宜、山田貴之、松島充代子、川部 勤、長谷川義大、式田光宏

    日本機械学会マイクロ・ナノ工学部門, 第7回 マイクロ・ナノ工学シンポジウム 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:朱鷺メッセ   Country:Japan  

  113. 気道内固定機能付きMEMS流量センサの開発

    原田直明、小野良太、松島充代子、川部 勤、長谷川義大、式田光宏

    日本機械学会マイクロ・ナノ工学部門, 第7回 マイクロ・ナノ工学シンポジウム 

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    Event date: 2015.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:朱鷺メッセ   Country:Japan  

  114. ガイダンス付スパイロメーターを用いた検査法の評価

    草次裕人、松島充代子、小木曽寛希、大村 綾、越智 悠、黒澤慎也、大崎理恵、川部 勤

    第10回臨床検査学教育学会学術大会 

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    Event date: 2015.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:信州大学医学部地域保健推進センター他   Country:Japan  

  115. 呼気を用いた非侵襲的TDM法の探索

    越智 悠、松島充代子、小木曽寛希、大村 綾、草次裕人、日置清香、山本良平、井上嘉則、山本 敦、川部 勤

    第10回臨床検査学教育学会学術大会 

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    Event date: 2015.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:信州大学医学部地域保健推進センター他   Country:Japan  

  116. Basket forceps with flow sensor for evaluating breathing characteristics in small airway International conference

    HARADA Naoaki, ONO Ryota , MATSUSHIMA Miyoko , KAWABE Tsutomu, SHIKIDA Mitsuhiro

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    Event date: 2015.7

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  117. Detection of both heartbeat and respiration signals from airflow at mouth using catheter flow sensor International conference

    KAWAOKA Hidenori, YAMADA Takayuki, MATSUSHIMA Miyoko , KAWABE Tsutomu, SHIKIDA Mitsuhiro

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    Event date: 2015.7

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  118. 有機リン系殺虫剤による免役応答修飾機構についての検討

    松島充代子、小笠原名奈子、河村奈美、山口剛広、高木健三、川部 勤

    第64回日本アレルギー学会学術大会 

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    Event date: 2015.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:グランドプリンスホテル新高輪国際館パミール   Country:Japan  

  119. ケルセチンのマウスARDSモデルに対する肺保護作用

    高嶋浩司、松島充代子、橋本克則、佐藤光夫、橋本直純、長谷川好規、川部 勤

    第55回日本呼吸器学会学術講演会 

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    Event date: 2015.4

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京国際フォーラム   Country:Japan  

  120. The effect of diazinon on macrophage activation.

    OOMURA Aya, MATSUSHIMA Miyoko, KODERA Yuka, SHIGA Marika, OGISO Hiroki, KAWABE Tsutomu

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    Event date: 2014.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  121. Protective effects of quercetin on lipopolysaccharide-induced acute lung injury.

    OGISO Hiroki, MATSUSHIMA Miyoko, KODERA Yuka, SHIGA Marika, OOMURA Aya, KAWABE Tsutomu

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    Event date: 2014.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  122. The involvement of cell membrane changes in quercetin-induced cytoprotective effects.

    KODERA Yuka, MATSUSHIMA Miyoko, SHIGA Marika, OOMURA Aya, OGISO Hiroki, KAWABE Tsutomu

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    Event date: 2014.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  123. Different mechanism of cytoprotective effects by flavonoids, quercetin and chrysin.

    SHIGA Marika, MATSUSHIMA Miyoko, KODERA Yuka, OOMURA Aya, OGISO Hiroki, KAWABE Tsutomu

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    Event date: 2014.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  124. SC光を用いたラット肺組織の3次元超高分解能OCTイメージングによる解析

    安藤栄充,川越寛之,服部雄治,山中真仁,松島充代子,高嶋浩司,長谷川好規,森健策,川部勤,西澤典彦

    日本光学会年次学術講演会Optics & Photonics Japan 2014 

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    Event date: 2014.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:筑波大学東京キャンパス文京校舎   Country:Japan  

  125. TLR7を介した肺胞マクロファージの活性化に対するケルセチンの効果

    小寺佑果、松島充代子、小笠原名奈子、武村和哉、志賀茉梨化、大村 綾、小木曽寛希、川部 勤

    第9回日本臨床検査学教育学会学術大会 

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    Event date: 2014.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大田区産業プラザ   Country:Japan  

  126. 肥満細胞活性化に対するクリシンとケルセチンの抑制効果とその機序の相違

    大村 綾、松島充代子、志賀茉梨化、草次裕人、小笠原名奈子、武村和哉、小寺佑果、小木曽寛希、川部 勤

    第9回日本臨床検査学教育学会学術大会 

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    Event date: 2014.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大田区産業プラザ   Country:Japan  

  127. Effects of quercetin on TLR7-mediated macrophage activation International conference

    Aya Oomura, Miyoko Matsushima, Nanako Ogasawara, Kazuya Takemura, Yuka Kodera, Marika Shiga, Hiroki Ogiso, Tsutomu Kawabe

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    Event date: 2014.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  128. Inhibitory action of mast cell degranulation by chrysin International conference

    Marika Shiga, Miyoko Matsushima, Yuto Kusatsugu, Nanako Ogasawara, Kazuya Takemura, Yuka Kodera, Aya Oomura, Hiroki Ogiso, Tsutomu Kawabe

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    Event date: 2014.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  129. マクロファージの免疫調節機能に及ぼすダイアジノンの効果

    松島充代子、小笠原名奈子、河村奈美、武村和哉、小寺佑果、志賀茉梨花、大村 綾、小木曽寛希、上山 純、川部 勤

    第45回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2014.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:福岡ソフトリサーチパーク(SRP)センタービル   Country:Japan  

  130. エアロゾル用吸着剤の開発と呼気中薬物分析への適用

    日置清香、三輪俊夫、山本良平、井上嘉則、山本 敦、松島充代子、川部 勤

    第21回クロマトグラフィーシンポジウム 

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    Event date: 2014.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋市工業研究所   Country:Japan  

  131. 非侵襲的治療薬物モニタリングのための呼気用新規吸着剤の開発

    日置清香、三輪俊夫、山本良平、井上嘉則、山本 敦、松島充代子、川部 勤

    日本薬学会第134年会 

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    Event date: 2014.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:熊本市総合体育館   Country:Japan  

  132. Chrysin suppresses mast cell activation via HO-1-independent pathway

    Marika Shiga, Miyoko Matsushima, Haruka Nose, Takehiro Yamaguchi, Yuka Kodera, Tsutomu Kawabe

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    Event date: 2013.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  133. The inhibitory effect of quercetin on TLR7-induced activation of alveolar macrophages

    Yuka Kodera, Miyoko Matsushima, Haruka Nose, Takehiro Yamaguchi, Marika Shiga, Tsutomu Kawabe

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    Event date: 2013.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  134. 環境物質曝露によるマクロファージの活性化に対するフラボノイドの効果とその機序

    山口剛広、松島充代子、川部 勤

    第63回日本アレルギー学会秋季学術大会 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ホテルニューオータニ   Country:Japan  

  135. TLR7を介した肺胞マクロファージの活性化に対するケルセチンならびにその誘導するHO -1の効果について

    安井正宏、松島充代子、川部 勤

    第63回日本アレルギー学会秋季学術大会 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:ホテルニューオータニ   Country:Japan  

  136. 正常・疾患ラット肺組織の3次元超高分解能OCTイメージング

    服部雄治、川越寛之、石田周太郎、荒巻光利、西澤典彦、松島充代子、高嶋浩司、長谷川好規、川部勤

    日本光学会年次学術講演会Optics & Photonics Japan 2013 

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    Event date: 2013.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:奈良   Country:Japan  

  137. Chrysin regulates mast cell activation via HO-1-independent pathway International conference

    Marika Shiga, Miyoko Matsushima, Ayaka Teranishi, Haruka Nose, Nanako Ogasawara, Kazuya Takemura, Takehiro Yamaguchi, Yuka Kodera, Tsutomu Kawabe

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    Event date: 2013.8

    Language:English   Presentation type:Poster presentation  

    Country:Italy  

  138. The effect of quercetin on the activated alveolar macrophages International conference

    Haruka Nose, Miyoko Matsushima, Aya Oomura, Kanae Mori, Nanako Ogasawara, Kazuya Takemura, Takehiro Yamaguchi, Yuka Kodera, Marika Shiga, Tsutomu Kawabe

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Italy  

  139. Difference in reaction patterns of M1 and M2 macrophages induced by quercetin International conference

    Miyoko Matsushima, Aya Oomura, Kanae Mori, Nanako Ogasawara, Kazuya Takemura, Haruka Nose, Takehiro Yamaguchi, Yuka Kodera, Marika Shiga, Tsutomu Kawabe

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Italy  

  140. Investigation on frequency of mutation in the gene segments of immunoglobulin in CD40 knockout mice International conference

    Yuka Kodera, Miyoko Matsushima, Hiroki Ogiso, Nanako Ogasawara, Kazuya Takemura, Haruka Nose, Takehiro Yamaguchi, Marika Shiga, Tsutomu Kawabe

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    Event date: 2013.8

    Language:English   Presentation type:Poster presentation  

    Country:Italy  

  141. 環境物質に対するフラボノイドの細胞保護効果とその機序

    松島充代子、小笠原名奈子、武村和哉、野瀬遥加、山口剛広、小寺佑果、志賀茉梨花、上山 純、川部 勤

    第44回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2013.7

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神奈川   Country:Japan  

  142. Three-dimensional ultrahigh-resolution optical coherence tomography imaging of lung tissues. International conference

    Shutaro Ishida, Norihiko Nishizawa, Masashi Kitatsuji, Hiroyoshi Ohshima, Miyoko Matsushima, and Tsutomu Kawabe.

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    Event date: 2013.2

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  143. The Effect of Quercetin on the Activation of Alveolar Macrophages

    Matsushima M, Nose H, Yamaguchi T, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  144. Analysis of IgE-binding epitope variation in the allergen after repeated immunization

    Yamaguchi T, Matsushima M, Nose H, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  145. Attenuation of Transforming Growth Factor-β-Stimulated Collagen Production in Fibroblasts by Chrysin

    Nose H, Matsushima M, Yamaguchi T, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  146. The Effect of Quercetin on the Activation of Alveolar Macrophages

    Matsushima M, Nose H, Yamaguchi T, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  147. Analysis of IgE-binding epitope variation in the allergen after repeated immunization

    Yamaguchi T, Matsushima M, Nose H, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  148. Attenuation of Transforming Growth Factor-β-Stimulated Collagen Production in Fibroblasts by Chrysin

    Nose H, Matsushima M, Yamaguchi T, Kawabe T.

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    Event date: 2012.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  149. 微細気流計を用いた喘息モデルマウスの気流変化の観察

    松島充代子、式田光宏、山本ゆき、吉川和宏、鹿野嵩瑛、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  150. 頻回な抗原の曝露によるIgE認識エピトープの解析

    山口剛広、松島充代子、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  151. 線維化に及ぼすクリシンの効果の検討

    野瀬遥加、松島充代子、太田川茅沙、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  152. 微細気流計を用いた喘息モデルマウスの気流変化の観察

    松島充代子、式田光宏、山本ゆき、吉川和宏、鹿野嵩瑛、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  153. 頻回な抗原の曝露によるIgE認識エピトープの解析

    山口剛広、松島充代子、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  154. 線維化に及ぼすクリシンの効果の検討

    野瀬遥加、松島充代子、太田川茅沙、川部 勤

    第62回日本アレルギー学会秋季学術大会 

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    Event date: 2012.11 - 2012.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪   Country:Japan  

  155. INTEGRATION OF TEMPERATURE DETECTION ONTO CATHETER FLOW SENSOR FOR BRONCHOSCOPE International conference

    Yamazaki T, Yoshikawa K, Shikida M, Matsushima M, Kawabe T.

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    Event date: 2012.10

    Language:English   Presentation type:Poster presentation  

    Country:Taiwan, Province of China  

  156. CATHETER FLOW SENSOR SYSTEM AND BREATHING MEASUREMENTS IN RABBIT International conference

    Matsuyama T, Yamazaki Y, Shikano T, Shikida M, Matsushima M, Kawabe T.

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    Event date: 2012.10

    Language:English   Presentation type:Poster presentation  

    Country:Taiwan, Province of China  

  157. INTEGRATION OF TEMPERATURE DETECTION ONTO CATHETER FLOW SENSOR FOR BRONCHOSCOPE International conference

    Yamazaki T, Yoshikawa K, Shikida M, Matsushima M, Kawabe T.

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    Event date: 2012.10

    Language:English   Presentation type:Poster presentation  

    Country:Taiwan, Province of China  

  158. CATHETER FLOW SENSOR SYSTEM AND BREATHING MEASUREMENTS IN RABBIT International conference

    Matsuyama T, Yamazaki Y, Shikano T, Shikida M, Matsushima M, Kawabe T.

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    Event date: 2012.10

    Language:English   Presentation type:Poster presentation  

    Country:Taiwan, Province of China  

  159. 超高分解能OCTによる肺組織の3次元高解像度断層イメージング

    西澤典彦、石田周太郎、北辻真史、大島啓嘉、松島充代子、川部勤

    日本光学会年次大会Optics & Photonics Japan 2012 

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    Event date: 2012.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  160. 超高分解能OCTによる肺組織の3次元高解像度断層イメージング

    西澤典彦、石田周太郎、北辻真史、大島啓嘉、松島充代子、川部勤

    日本光学会年次大会Optics & Photonics Japan 2012 

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    Event date: 2012.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  161. IgE結合部位からみたアレルゲンの抗原性の変化

    山口剛広、松島充代子、川部 勤

    第7回日本臨床検査教育協議会 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:愛知   Country:Japan  

  162. 膠原線維産生に及ぼすクリシンの効果についての検討

    野瀬遥加、松島充代子、太田川茅沙、川部 勤

    第7回日本臨床検査教育協議会 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:愛知   Country:Japan  

  163. IgE結合部位からみたアレルゲンの抗原性の変化

    山口剛広、松島充代子、川部 勤

    第7回日本臨床検査教育協議会 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:愛知   Country:Japan  

  164. 膠原線維産生に及ぼすクリシンの効果についての検討

    野瀬遥加、松島充代子、太田川茅沙、川部 勤

    第7回日本臨床検査教育協議会 

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    Event date: 2012.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:愛知   Country:Japan  

  165. Detection of airflow change by thermal flow microsensor in disease model rabbits International conference

    Matsushima M, Shikida M, Yamamoto Y, Shikano T, Yoshikawa K, Kawabe T.

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    Event date: 2012.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  166. Detection of airflow change by thermal flow microsensor in disease model rabbits International conference

    Matsushima M, Shikida M, Yamamoto Y, Shikano T, Yoshikawa K, Kawabe T.

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    Event date: 2012.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  167. 超高分解能OCTを用いた正常ならびに疾患肺の組織学的検討

    高嶋浩司、松島充代子、西澤典彦、北辻真史、大島博嘉、長谷川好規、川部 勤

    第52回日本呼吸器学会学術講演会 

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    Event date: 2012.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:兵庫   Country:Japan  

  168. 超高分解能OCTを用いた正常ならびに疾患肺の組織学的検討

    高嶋浩司、松島充代子、西澤典彦、北辻真史、大島博嘉、長谷川好規、川部 勤

    第52回日本呼吸器学会学術講演会 

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    Event date: 2012.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:兵庫   Country:Japan  

  169. TGF-beta-stimulated collagen production in fibroblasts is attenuated by quercetin-induced heme oxygenase-1

    Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Hasegawa Y, Kawabe T.

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    Event date: 2012.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  170. TGF-beta-stimulated collagen production in fibroblasts is attenuated by quercetin-induced heme oxygenase-1

    Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Hasegawa Y, Kawabe T.

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    Event date: 2012.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  171. 肥満細胞活性化におけるクリシンの効果

    松島充代子、寺西彩香、小笠原名奈子、山本祐規子、高木 健三、川部 勤

    第132回日本薬学会 

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    Event date: 2012.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:北海道   Country:Japan  

  172. 肥満細胞活性化におけるクリシンの効果

    松島充代子、寺西彩香、小笠原名奈子、山本祐規子、高木 健三、川部 勤

    第132回日本薬学会 

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    Event date: 2012.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:北海道   Country:Japan  

  173. ケルセチンの誘導するheme oxygenase-1 によるコラーゲン産生の抑制作用

    中村俊信、松島充代子、長谷川好規、川部 勤

    第24回気道病態研究会 

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    Event date: 2012.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  174. MEASUREMENT OF BREATHING CHARACTERISTIC IN MOUSE DURING INHALING DRUG. International conference

    Shikano T., Shikida M., Matsushima M., Kawabe T., and Sato K.

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    Event date: 2012.1 - 2012.2

    Language:English   Presentation type:Poster presentation  

    Country:France  

  175. Ultrahigh resolution optical coherence tomography imaging of diseased rat lung using Gaussian shaped super continuum sources International conference

    Nishizawa N., Ishida S., Kitatsuji M., Ohshima H., Hasegawa Y., Matsushima M., and Kawabe T

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    Event date: 2012.1

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Country:United States  

  176. 抗原に対する抗体の高親和性獲得におけるCD40の役割

    山本祐規子、松島充代子、寺西彩香、髙木健三、川部 勤

    第61回日本アレルギー学会秋季学術大会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  177. クリシンの脱顆粒抑制機序の検討

    寺西彩香、松島充代子、山本祐規子、高木健三、川部 勤

    第61回日本アレルギー学会秋季学術大会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  178. ケルセチンの抗線維化作用とHO-1の関与

    松島充代子、中村俊信、今泉和良、長谷川好規、川部 勤

    第61回日本アレルギー学会秋季学術大会 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  179. Ultrahigh resolution OCT imaging of lung tissues

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  180. Analysis on the inhibitory effect of chrysin in mast cell degranulation

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  181. 肺組織観察用超高分解能OCTの開発と基礎的検討

    松島充代子、西澤典彦、石田周太郎、山本ゆき、北辻真史、大島啓嘉、長谷川好規、川部 勤

    第49回東海喘息研究会 

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    Event date: 2011.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  182. Heme oxygease-1 induced by quercetin attenuates TGF-beta-stimulated collagen productionin fibroblasts. International conference

    Kawabe T, Nakamura T, Matsushima M, Hayashi Y, Shibasaki M, Imaizumi K, Hashimoto N, Shimokata K, Hasegawa Y.

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    Event date: 2011.9

    Language:English   Presentation type:Poster presentation  

    Country:Netherlands  

  183. Development of thermal flow microsensor for transbronchial measurement of local lung function International conference

    Matsushima M, Shikida M, Yamamoto Y, Yamamoto Y, Iwai S, Shikano T, Kawabe T

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    Event date: 2011.7

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  184. 脱顆粒抑制能をもつクリシンの作用機序の検討

    寺西彩香、松島充代子、森 朱美、山本祐規子、髙木健三、川部 勤

    第42回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2011.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  185. 肺組織観察用超分解能OCTの開発

    松島充代子、長谷川好規、川部 勤

    第23回日本アレルギー学会春季臨床大会 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:千葉   Country:Japan  

  186. 胸膜を介した肺組織用超分解能OCTの開発と基礎的検討

    山本祐規子、松島充代子、山本ゆき、西澤典彦、石田周太郎、北辻真史、大島啓嘉、川部 勤

    第23回気道病態研究会 

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    Event date: 2011.3

    Language:Japanese  

    Venue:東京   Country:Japan  

  187. 微細気流計を用いた経気管支的局所肺機能検査のための基礎的検討

    松島充代子、山本祐規子、山本ゆき、式田光宏、岩井 聡、川部 勤

    第23回気道病態研究会 

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    Event date: 2011.3

    Language:Japanese  

    Venue:東京   Country:Japan  

  188. クリシンの抗アレルギー作用におけるHO-1の意義.

    松島充代子,森 朱美,寺西彩香,山本祐規子,高木健三,川部 勤

    第131回日本薬学会 

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    Event date: 2011.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:要旨集   Country:Japan  

  189. Ex-vivo ultra-high-resolution optical coherence tomography imaging of fine lung structure by use of a high-power Gaussian-like supercontinuum at 0.8-um wavelength International conference

    Nishizawa N., Ishida S., Ohta T. Itoh K., Kitatsuji M., Ohshima H., Hasegawa Y., Matsushima M., and Kawabe T.

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    Event date: 2011.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:United States  

  190. Ultrahigh resolution optical coherence tomography imaging of lung structure using Gaussian shaped super continuum sources International conference

    Nishizawa N., Ishida S., Ohta T. Itoh K., Kitatsuji M., Ohshima H., Hasegawa Y., Matsushima M., and Kawabe T.

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    Event date: 2011.1

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  191. クリシンの抗アレルギー作用とHO-1の関与

    寺西彩香、松島充代子、森 朱美、山本祐規子、髙木健三、川部 勤

    第60回日本アレルギー学会秋季学術大会 

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    Event date: 2010.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  192. Ultrahigh resolution optical coherence tomography imaging of lung tissue using Gaussian shaped super continuum sources

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    Event date: 2010.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  193. 肥満細胞のTNF-産生に対するフラボノイドの効果とHO-1の関与

    森 朱美、松島充代子、寺西彩香、山本祐規子、髙木健三、川部 勤

    第60回日本アレルギー学会秋季学術大会 

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    Event date: 2010.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  194. IgEの結合部位からみたアレルギーの病態解明

    松島充代子、川部 勤

    第47回東海喘息研究会 

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    Event date: 2010.9

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  195. ペプチドアレイへのIgE/IgG4の結合パターンによるミルクアレルギー診断

    片山真、加藤竜司、大河内美奈、本多裕之、川部勤、松島充代子、川瀬三雄、吉田安子、高瀬智和

    化学工学会第42回秋季大会 

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    Event date: 2010.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都   Country:Japan  

  196. Structure-activity relationship of flavonoids for anti-allergic effects and the induction of heme oxygenase-1 in RBL-2H3 cells International conference

    MATSUSHIMA Miyoko, HIRAYAMA Tatsuya, MORI Akemi, KAWABE Tsutomu

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    Event date: 2010.8

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  197. フラボノイドの抗アレルギー作用およびHO-1の発現誘導を決定する構造の探索

    松島充代子、髙木健三、森 朱美、寺西彩香、山本祐規子、川部 勤

    第41回日本職業・環境アレルギー学会総会・学術大会 

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    Event date: 2010.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:群馬   Country:Japan  

  198. Implantable flow sensor into airway for laboratory animal International conference

    MATSUNAGA Naoyuki., YOKOTA Takuo., SHIKIDA Mitsuhiro., KAWABE Tsutomu., MATSUSHIMA Miyoko., IWAI Satoshi., SATO Kazuo

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    Event date: 2010.7

    Language:English   Presentation type:Poster presentation  

    Country:Australia  

  199. フラボノイドのHO-1を介した抗アレルギー作用とC環2重結合の意義

    森 朱美、松島充代子、寺西彩香、山本祐規子、髙木健三、川部 勤

    第6回日本食品免疫学会 

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    Event date: 2010.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  200. フラボノイドによるHO-1を介した抗アレルギー作用とその構造

    森 朱美、川部 勤、松島充代子、平山達也、高木健三

    第22回日本アレルギー学会春季臨床大会 

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    Event date: 2010.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:京都   Country:Japan  

  201. 0.8um 帯超高分解能OCT を用いた高解像度肺組織イメージング

    西澤典彦、石田周太郎、太田健史、伊東一良、北辻真史、大島啓嘉、松島充代子、川部 勤

    第57回応用物理学関係連合講演会 

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    Event date: 2010.3

    Language:Japanese  

    Venue:神奈川   Country:Japan  

  202. HO-1を介したフラボノイドの抗アレルギー活性と構造活性相関

    森 朱美、川部 勤、松島充代子、平山達也、高木健三

    第22回気道病態研究会 

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    Event date: 2010.2

    Language:Japanese  

    Venue:東京   Country:Japan  

  203. Structure-activity relationship of flavonoids for anti-allergic effects by induced heme oxygenase-1

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    Event date: 2009.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  204. Ghrelin and Obestatin Activate Rat Peritoneal Mast Cells as Basic Secretagogues

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    Event date: 2009.12

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  205. フラボノイドの構造によるHO-1発現誘導能の差と抗アレルギー作用の検討

    松島充代子、川部 勤、平山達也、森 朱美、高木健三

    第59回日本アレルギー学会秋季学術大会 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:秋田   Country:Japan  

  206. グレリンおよびオベスタチンによる肥満細胞活性化機序の検討

    平山 達也、川部 勤、松島充代子、森 朱美、高木健三

    第59回日本アレルギー学会秋季学術大会 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Poster presentation  

    Venue:秋田   Country:Japan  

  207. 動物実験用気道埋め込み型流量センサの開発

    岩井 聡、松永直之、横田拓央、式田光宏、川部 勤、松島充代子、佐藤一雄

    電気学会センサ・マイクロマシン部門主催 第26回「センサ・マイクロマシンと応用システム」シンポジウム 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:東京   Country:Japan  

  208. 構造によるフラボノイドの抗アレルギー作用の検討

    平山達也、川部 勤、松島充代子、森 朱美、高木健三

    第40回日本職業・環境アレルギー学会総会 

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    Event date: 2009.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  209. Heme oxygenase-1 mediates the anti-allergic actions of quercetin in rodent mast cells International conference

    MATSUSHIMA Miyoko., KAWABE Tsutomu, HIRAYAMA Tatsuya., MORI Akemi., TAKAGI Kenzo.

    19th Congress of Interasma Japan North Asia 

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    Event date: 2009.7

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  210. 牛乳アレルゲン由来の30種ペプチドアレイ開発の試み

    松本直樹、松島充代子、伊藤浩明、坂本龍雄、川部 勤

    第21回日本アレルギー学会春季臨床大会 

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    Event date: 2009.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岐阜   Country:Japan  

  211. グレリンによる肥満細胞のヒスタミン遊離機序の検討

    松島充代子、川部 勤、太田裕以、平山達也、高木健三

    第21回気道病態研究会 

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    Event date: 2009.2

    Language:Japanese  

    Venue:東京   Country:Japan  

  212. ヘモグロビンによるindoleamine 2,3-dioxygenaseの骨髄系樹状細胞における発現の誘導機構

    小笠原名奈子、小黒崇史、坂部肇胤、松島充代子、滝川 修、長瀬文彦

    第38回日本トリプトファン研究会 

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    Event date: 2008.12

    Language:Japanese  

    Venue:岡山   Country:Japan  

  213. Myricetin involved heme oxygenase-1 in its anti-allergic actions.

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    Event date: 2008.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  214. Induction of the indoleamine 2,3-dioxygenase expression in myeloid dendritic cells stimulated with hemoglobin

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    Event date: 2008.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  215. ミルクアレルギー患者のIgE認識エピトープの高集密ペプチドアレイによる検討

    川部 勤、松島充代子、松本直樹、伊藤浩明、坂本龍雄

    第58回日本アレルギー学会総会 

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    Event date: 2008.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  216. 構造によるフラボノイドの抗アレルギー作用の検討

    太田裕以、川部 勤、松島充代子、平山達也、高木健三

    第58回日本アレルギー学会総会 

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    Event date: 2008.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  217. グレリンによる肥満細胞活性化機序の検討

    平山達也、川部 勤、松島充代子、太田裕以、高木健三.

    第58回日本アレルギー学会総会 

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    Event date: 2008.11

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  218. ミルクアレルギー診断のための高集密ペプチドアレイの作製と解析

    本多裕之、加藤竜司、竹下敏一、大河内美奈、川部 勤、松島充代子、松本 直樹、坂本龍雄、廣瀬悦子、川瀬三雄、吉田 安子、高瀬 智和、小川 昭子

    化学工学会第40回秋季大会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:宮城   Country:Japan  

  219. ケンフェロールの抗アレルギー活性発現におけるHO-1の役割

    太田裕以、川部 勤、松島充代子、廣瀬悦子、平山達也、高木健三

    第39回日本職業・環境アレルギー学会 

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    Event date: 2008.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  220. ミリセチンの抗アレルギー作用機序の検討

    太田裕以、川部 勤、松島充代子、平山達也、高木健三

    第20回日本アレルギー学会春季臨床大会 

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    Event date: 2008.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京   Country:Japan  

  221. 肥満細胞におけるケルセチンの抗アレルギー作用機序の検討

    松島充代子、川部 勤、廣瀬悦子、太田裕以、平山達也、高木健三.

    第128回日本薬学会 

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    Event date: 2008.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜   Country:Japan  

  222. heme oxygenase(HO)-1誘導を介したミリセチンによる脱顆粒の抑制

    太田裕以、川部 勤、松島充代子、廣瀬悦子、高木健三

    第128回日本薬学会 

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    Event date: 2008.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜   Country:Japan  

  223. ミリセチンの抗アレルギー作用における抗炎症酵素 (HO-1)の役割

    太田裕以、川部 勤、松島充代子、廣瀬悦子、高木健三

    第20回気道病態シンポジウム 

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    Event date: 2008.2

    Language:Japanese  

    Venue:東京   Country:Japan  

  224. Anti-allergic actions of quercetin are mediated by heme oxygenase-1 in RBL-2H3 cells

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    Event date: 2007.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  225. ケンフェロールの抗アレルギー作用におけるHeme oxygenase (HO)-1の役割

    廣瀬悦子、川部 勤、松島充代子、松本直樹、太田裕以、高木健三

    第57回日本アレルギー学会総会 

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    Event date: 2007.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  226. 肥満細胞におけるケルセチンのHO-1活性化制御の検討

    太田裕以、川部 勤、松島充代子、松本直樹、廣瀬悦子、高木健三

    第57回日本アレルギー学会総会 

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    Event date: 2007.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  227. ケルセチンの抗アレルギー作用におけるheme oxygenase (HO)-1の役割

    松島充代子、川部 勤、小川三由紀、廣瀬悦子、古部裕子、太田裕以、安部文江、高木健三

    第19回日本アレルギー学会春季臨床大会 

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    Event date: 2007.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  228. 肥満細胞におけるケンフェロールの抗アレルギー作用の検討

    小川三由紀,川部 勤,松島充代子,安部文江, 長谷川高明,高木健三

    第56回日本アレルギー学会総会 

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    Event date: 2006.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  229. フラボノイドの抗アレルギー作用における抗炎症性酵素の役割

    松島充代子, 川部 勤, 小川三由紀,廣瀬悦子,安部文江, 高木健三

    第2回免疫医学研究会 

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    Event date: 2006.10

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  230. ラボノイドによる抗アレルギー作用の新規機序の検討

    松島充代子, 川部 勤, 小川三由紀,廣瀬悦子,安部文江, 高木健三

    第8回東海分子呼吸器研究会 

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    Event date: 2006.8

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  231. フラボノイドの生体における抗アレルギー作用の検討

    松島充代子, 川部 勤, 小川三由紀,安部文江,長谷川高明, 高木健三

    第18回日本アレルギー学会春季臨床大会 

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    Event date: 2006.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京   Country:Japan  

  232. 肥満細胞におけるフラボノイドの抗アレルギー作用の検討

    松島充代子, 川部 勤, 小川三由紀,安部文江,長谷川高明, 高木健三

    第55回日本アレルギー学会総会 

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    Event date: 2005.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岩手   Country:Japan  

  233. ケルセチンの抗アレルギー作用の検討

    松島充代子, 川部 勤, 小川三由紀,安部文江,高木健三

    第37回東海喘息研究会 

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    Event date: 2005.9

    Language:Japanese  

    Venue:名古屋   Country:Japan  

  234. 健康補助食品が肥満細胞の脱顆粒に及ぼす影響

    松島充代子, 川部 勤, 小川三由紀,安部文江,長谷川高明, 高木健三

    第36回職業・環境アレルギー学会 

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    Event date: 2005.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  235. 肥満細胞におけるフラボノイドの抗アレルギー作用の検討

    松島充代子, 川部 勤, 田中成一,長谷川高明, 高木健三

    第17回日本アレルギー学会春季臨床大会 

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    Event date: 2005.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:岡山   Country:Japan  

  236. フラボノイドによる抗アレルギー作用の検討

    松島充代子, 川部 勤, 青山真梨子,田中成一,長谷川高明, 高木健三

    第17回気道病態シンポジウム 

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    Event date: 2005.2

    Language:Japanese  

    Venue:東京   Country:Japan  

  237. Adrenomedullinによるラット腹腔肥満細胞からのヒスタミン遊離におけるG蛋白の関与

    松島充代子,北市清幸,田中成一,長谷川高明,高木健三

    第124回日本薬学会年会 

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    Event date: 2004.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大阪   Country:Japan  

  238. 生理活性ペプチドにおけるラット肥満細胞からのヒスタミン遊離機構に関する研究

    松島充代子, 北市清幸, 田中成一,長谷川高明, 高木健三.

    第16回気道病態シンポジウム 

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    Event date: 2004.1

    Language:Japanese  

    Venue:東京   Country:Japan  

  239. ヒスタミン高感度測定系の確立に関する基礎的検討

    松島充代子,北市清幸,田中成一,高木健三

    第4回愛知県医学検査学会 

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    Event date: 2003.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  240. ラット腹腔肥満細胞からのヒスタミン遊離に対するAdrenomedullin の効果

    松島充代子, 北市清幸, 田中成一, 巽 康彰, 長谷川高明, 高木健三

    第123回日本薬学会年会 

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    Event date: 2003.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:長崎   Country:Japan  

  241. ラット腹腔肥満細胞からのヒスタミン遊離に及ぼすAdrenomedullinおよびCGRPの効果

    松島充代子, 北市清幸, 巽 康彰, 長谷川高明, 高木健三

    第52回日本アレルギー学会総会 

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    Event date: 2002.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:横浜   Country:Japan  

  242. Methamphetamine: sensitization and pharmacokinetics International conference

    KITAICHI Kiyoyuki., MORISHITA Yuki., UEYAMA Jun., MATSUSHIMA Miyoko., TAKAGI Kenzo, TAKAGI Kenji., HASEGAWA Takaaki.

    XII World Congress of Psychiatry 

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    Event date: 2002.8

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  243. Pharmacokinetic changes of methamphetamine and their mechanisms in rats having behavioral sensitization to methamphetamine International conference

    KITAICHI Kiyoyuki., MORISHITA Yuki., UEYAMA Jun., MATSUSHIMA Miyoko., Zhao Y.L., TAKAGI Kenji., HASEGAWA Takaaki.

    23rd Congress of Collegium Internationale Neuro-Psychopharmacologicum 

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    Event date: 2002.6

    Language:English   Presentation type:Poster presentation  

    Country:Canada  

  244. MEMS FLOW SENSOR CAPABLE OF MEASURING MULTI-VITAL SIGNS OF RESPIRATION, HEART RATE, AND BODY TEMPERATURE

    Hasegawa Yoshihiro, Lee Seunghyeon, Matsushima Miyoko, Hasegawa Shin, Kawabe Tsutomu, Shikida Mitsuhiro

    2021 21ST INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS, ACTUATORS AND MICROSYSTEMS (TRANSDUCERS)  2021 

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    Language:Japanese  

    DOI: 10.1109/TRANSDUCERS50396.2021.9495387

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Research Project for Joint Research, Competitive Funding, etc. 5

  1. 気管挿管時の換気物理量解析による心機能評価可能な呼吸・循環監視装置の開発

    2021.11 - 2022.11

    公益財団法人鈴木謙三記念医科学応用研究財団 

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    Grant amount:\1000000

  2. 環境物質に対するフラボノイドの細胞保護効果とその機序

    2014.4 - 2015.3

    那古野医学振興会  

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    Grant type:Competitive

  3. フラボノイドによる抗アレルギー活性の新規機序の解明

    2010.4 - 2011.3

    那古野医学振興会  

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    Grant type:Competitive

  4. フラボノイドの抗アレルギー作用機序の解明

    2008.4 - 2009.3

    市原国際奨学財団 

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    Grant type:Competitive

  5. フラボノイドの抗アレルギー作用についての研究

    2008.4 - 2009.3

    名古屋大学学術振興基金 

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    Grant type:Competitive

KAKENHI (Grants-in-Aid for Scientific Research) 7

  1. フラボノイドの作用機序から探る細胞保護作用の発動機構の解明

    2013.4 - 2015.3

    科学研究費補助金  若手研究(B)

    松島充代子

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    Authorship:Principal investigator 

  2. フラボノイドが誘導するHO‐1を介した急性肺障害の新規治療法開発の基礎的検討

    2010.4 - 2013.3

    科学研究費補助金  基盤研究(C)

    川部 勤

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    Authorship:Coinvestigator(s) 

  3. ストレスセンシング機構を標的としたフラボノイドの細胞保護作用発動機構の解明

    Grant number:20K11529  2020.4 - 2023.3

    科学研究費補助金  

    松島 充代子

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

    フラボノイドは天然の機能性成分で、多彩な細胞保護効果を示す。本研究ではフラボノイドは共通した起点となる細胞膜でセンシングされ、普遍的な生体防御機構を誘導すると考え、細胞がフラボノイドを感知するストレスセンシング機構を探索・同定し、フラボノイドの多彩な細胞保護効果の発揮の出発点となる分子機構を解明する。

  4. マクロファージを主軸とする自然免疫応答から探求する傷害組織の修復機構の解明

    Grant number:20K07824  2020.4 - 2023.3

    科学研究費補助金  

    川部 勤

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\600000 ( Direct Cost: \600000 )

    マクロファージの組織の修復機転、特に死細胞を貪食処理するエフェロサイトーシスに自然免疫の環境がどのような意義を持つのか、マクロファージの他、修復機構に重要な働きをすると考えられる、傷害部位の組織構成細胞や自然リンパ球がどのように協働しているかを解明する。本研究により解明される有効な修復機構を誘導することで、組織傷害に対してより完全な修復・治癒機転の招来をもたらす。

  5. Analysis of adverse effects of acetylcholinergic pesticides focused on the induction of host defense reaction and immune disruption

    Grant number:17K00547  2017.4 - 2020.3

    Kawabe Tsutomu

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\600000 ( Direct Cost: \600000 )

    In this study, we investigated the effects of acetylcholinergic pestcides, particularly neonicotinoid pesticides, on the induction of host defense reaction and functions of macrophages and T cells. We showed that acetamiprid modulated the function of alveolar macrophages. Briefly, acetamiprid inhibited the levels of inflammatory cytokine mRNA expression and phagocytosis induced by imiquimod, a ligand of TLR7, in alveolar macrophages, while acetamiprid exhibited little effect on the induction of host defense reaction including HO-1 expression and autophagy. Moreover, acetamiprid did not affect T-cell activation. These results suggested the possibility that acetamiprid could influence the host defense reaction in the lung.

  6. The role of cell membrane in cytoprotective effects of flavonoids

    Grant number:15K08228  2015.4 - 2018.3

    Matsushima Miyoko

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4810000 ( Direct Cost: \3700000 、 Indirect Cost:\1110000 )

    Flavonoids, which are contained in fruit and vegetables, exhibit wide variety of cytoprotective effects. We previously reported that quercetin exerted various cytoprotective effects via nuclear factor E2-related factor 2 (Nrf2)-heme oxygenase (HO)-1 pathway. In this study, we focused on cell membrane, which is the first line to interact with extracellular environment and plays an important role in cellular signaling, and investigated the involvement of cell membrane changes in quercetin-induced cytoprotective effects. We showed that quercetin changed the formation of lipid rafts by depleting cholesterol from cell membrane. The expression levels of caveolin-1 and Nrf2 localized in cell membrane were also decreased, and caveolin-1-Nrf2 complex was translocated to cytosol and nucleus. These findings suggested that translocation of caveolin-1-Nrf2 complex to nucleus might lead the induction of HO-1.

  7. Study on non-invasive assessment of pharmacokinetics by exhaled breath

    Grant number:15K07903  2015.4 - 2018.3

    YAMAMOTO Atsushi

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    The method was established to collect the drug in exhaled breath of rat administered theophylline. The rat expiratory volume per time was uncertain, however, the search of endogenous biomarkers for the expiratory volume was left as a pending problem.
    The analysis of fexofenadine, an antihistamine pharmaceutical drug, in human breath and blood could not meet good correlation. There was no tendency for the determined amount of fexofenadine in breath to decrease with the elapsed time. The existence of the blood-lung interface was suggested. Although the exhaled breath condensate was used for breath analysis, there was a tendency for low collection rate of the breath aerosol. The filter sampling method for the aerosol would be desired.

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Teaching Experience (On-campus) 17

  1. Immunology

    2021

  2. Advanced Topics of Cellular and Genetic Sciences

    2021

  3. Advanced Topics on Host Defense Sciences

    2021

  4. Laboratory Immunology I

    2021

  5. Immunology

    2021

  6. Laboratory Microbiology Practice C

    2021

  7. Clinical Microbiology Practice A

    2021

  8. Laboratory Immunology II

    2021

  9. Laboratory Immunology PracticeA

    2020

  10. Basic Training

    2020

  11. 免疫学実習

    2015

  12. 病原微生物学実習

    2015

  13. 病因検査技術開発法Ⅱ

    2015

  14. 遺伝子検査学実習

    2015

  15. 病因検査技術開発法Ⅰ

    2015

  16. 病原微生物検査学実習A

    2015

  17. 免疫学実習A

    2015

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Teaching Experience (Off-campus) 1

  1. 解剖生理学実験

    2015.4 Tokai Gakuen University)

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    Level:Undergraduate (specialized) 

 

Social Contribution 1

  1. 第28回アレルギー週間市民公開講座

    Role(s):Presenter, Planner, Organizing member

    日本アレルギー協会東海支部  2022.2

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    Audience: General

    Type:Lecture