Updated on 2022/07/01

写真a

 
SAITO, Susumu
 
Organization
Integrated Research Consortium on Chemical Sciences Professor
Graduate School
Graduate School of Science
Title
Professor
Contact information
メールアドレス

Degree 3

  1. Doctor of Engineering ( 1998.9   Nagoya University ) 

  2. Master of Engineering ( 1993.3   Nagoya University ) 

  3. 学士(工学) ( 1991.3   名古屋大学 ) 

Research Interests 15

  1. CO2

  2. Molecular photocatalysis

  3. Biorenewables

  4. Organic Chemistry

  5. Water

  6. Synthetic Chemistry

  7. Molecular Catalysis

  8. Hydrogenation

  9. Hydrogen Transfer

  10. Hydrogen Bonds

  11. Semicondutor photocatalysis

  12. amides

  13. Carboxylic acids

  14. Alcohol

  15. Renewable Resources

Research Areas 3

  1. Others / Others  / Engineering@Industrial Chemistry@Industrial Organic Chemistry

  2. Others / Others  / Engineering@Industrial Chemistry@Synthetic Chemistry

  3. Nanotechnology/Materials / Synthetic organic chemistry

Current Research Project and SDGs 7

  1. Artificial photosynthesis: CO2 transformation

  2. 人工光合成:水を使う

  3. カルボン酸類(カルボン酸・アミド・エステル)の還元と触媒的変換

  4. バイオマス資源物質の活性化と変換

  5. 中性的酸塩基複合型触媒作用のデザインと有機合成への応用

  6. 多官能性触媒化学

  7. Selective Organic Synthesis Using Designer Lewis Acids

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Research History 7

  1. Nagoya University   Research Center for Materials Science   Professor

    2019.4

  2. Nagoya University   Graduate School of Science Division of Material Science Organic Chemistry and Biochemistry   Professor

    2015.3 - 2019.3

  3. Nagoya University   Associate professor

    2007.4 - 2015.2

  4. Nagoya University   Assistant Professor

    2002.10 - 2007.3

  5. Nagoya University   Assistant

    1997.4 - 2002.9

  6. Nagoya University   Assistant

    1995.5 - 1997.3

  7. Nagoya University   Researcher

    1993.4 - 1995.4

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Education 3

  1. Nagoya University

    1993.4

  2. Nagoya University   Graduate School, Division of Engineering

    1991.4 - 1993.3

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    Country: Japan

  3. Nagoya University   Faculty of Engineering

    1987.4 - 1991.3

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    Country: Japan

Professional Memberships 7

  1. 先端錯体工学研究会

    2016.4

  2. 東海化学工業会

    2015.4

  3. American Chemical Society

  4. Catalysis Society of Japan

  5. 有機合成化学協会

  6. 日本化学会

  7. The Japanese Photochemistry Association

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Committee Memberships 15

  1. 東海化学工業会   会計幹事  

    2021.4   

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    Committee type:Academic society

  2. 日本学術振興会   卓越研究員候補者選考委員会書面審査員  

    2017.5 - 2017.7   

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    Committee type:Government

  3. 東海化学工業会   幹事  

    2017.4 - 2021.3   

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    Committee type:Academic society

  4. 日本触媒学会   世話人  

    2017.3   

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    Committee type:Academic society

  5. 戦略的国際共同研究プログラム(SICROP)   特別研究員等審査会専門委員及び国際事業委員会書面審査員・書面評価員  

    2016.8 - 2017.7   

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    Committee type:Government

  6. 日本化学会   代表正会員  

    2015.4 - 2017.3   

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    Committee type:Academic society

  7. 日本学術振興会   科学研究費委員会 専門委員  

    2013.12 - 2015.11   

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    Committee type:Government

  8. 有機金属化学国際会議   ICOMC2014 組織委員  

    2013.3 - 2013.7   

  9. 有機合成化学協会   協会誌編集協力委員  

    2011.2   

  10. 日本化学会東海支部   代議員  

    2009.4 - 2011.3   

  11. 東海化学工業会   表彰審査委員  

    2009.4 - 2011.3   

  12. 文部科学省 科学技術・学術審議会   専門委員  

    2007.2 - 2009.1   

  13. 日本化学会東海支部   支部便り編集委員  

    2006.4 - 2007.3   

  14. 日本化学会東海支部   幹事  

    2005.4 - 2007.3   

  15. 野依フォーラム   世話人  

    2003.4   

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Awards 10

  1. 非常勤講師

    2022.4   九州大学先導物質化学研究所  

  2. 客員教授

    2019.10   中華人民共和国 南京理工大学化学工学科  

  3. SSOCJ Tosoh Award for Environment and Energy 2018

    2019.2   Development of Catalytic Hydrogenation of Carboxylic Acid and Its Derivatives Using Organometallic Complexes

    SAITO, Susumu

  4. Nagase Research Award 2018

    2018.4  

    SAITO, Susumu

  5. 非常勤講師

    2017.10   群馬大学大学院理工学府学府  

    斎藤 進

  6. Asian Core Program (ACP) Lectureship Award from China

    2009.12   International Conference on Curring-Edge Organic Chemistry in Asia (ICCEOCA)  

  7. Asian Core Program (ACP) Lectureship Award from Taiwan

    2009.12   International Conference on Curring-Edge Organic Chemistry in Asia (ICCEOCA)  

  8. Visiting Lecturer of Institute for Materials Chemistry and Engineering, Kyushu University

    2009.4   Institute for Materials Chemistry and Engineering, Kyushu University  

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    Country:Japan

  9. Visiting Associate Professor of Institute for Chemical Research, Kyoto University

    2004.4   Institute for Chemical Research Kyoto University  

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    Country:Japan

  10. The 50th Japan Chemical Society Award for DIstinguished Young Chemists

    2001.3   Japan Chemical Society  

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    Country:Japan

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Papers 119

  1. Selective reduction of carboxylic acids to alcohols in the presence of alcohols by a dual bulky transition metal complex/Lewis acid catalyst Reviewed

    Bendik Grømer, Shota Yoshioka, Susumu Saito*

    ACS Catal.   Vol. 12   page: 1957 - 1964   2022.1

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acscatal.1c04392

  2. C(sp3)–H Bond Functionalization with Styrenes via Hydrogen-Atom Transfer to an Aqueous Hydroxyl Radical under Photocatalysis Reviewed

    Shogo Mori, Susumu Saito

        2021.4

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    Language:English  

    DOI: 10.1039/D1GC00753J

  3. Reaction of H2 with mitochondria-relevant metabolites using a multifunctional molecular catalyst Reviewed

    Shota Yoshioka, Sota Nimura, Masayuki Naruto, Susumu Saito

    Science Advances   Vol. 6 ( 43 ) page: eabc0274 - eabc0274   2020.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Association for the Advancement of Science (AAAS)  

    The Krebs cycle is the fuel/energy source for cellular activity and therefore of paramount importance for oxygen-based life. The cycle occurs in the mitochondrial matrix, where it produces and transfers electrons to generate energy-rich NADH and FADH<sub>2</sub>, as well as C<sub>4</sub>-, C<sub>5</sub>-, and C<sub>6</sub>-polycarboxylic acids as energy-poor metabolites. These metabolites are biorenewable resources that represent potential sustainable carbon feedstocks, provided that carbon-hydrogen bonds are restored to these molecules. In the present study, these polycarboxylic acids and other mitochondria-relevant metabolites underwent dehydration (alcohol-to-olefin and/or dehydrative cyclization) and reduction (hydrogenation and hydrogenolysis) to diols or triols upon reaction with H<sub>2</sub>, catalyzed by sterically confined iridium–bipyridyl complexes. The investigation of these single–metal site catalysts provides valuable molecular insights into the development of molecular technologies for the reduction and dehydration of highly functionalized carbon resources.

    DOI: 10.1126/sciadv.abc0274

    Web of Science

  4. Photocatalytic CO2 Reduction Using a Robust Multifunctional Iridium Complex toward the Selective Formation of Formic Acid Reviewed

    Kenji Kamada, Jieun Jung, Taku Wakabayashi, Keita Sekizawa, Shunsuke Sato, Takeshi Morikawa, Shunichi Fukuzumi, Susumu Saito

    Journal of the American Chemical Society   Vol. 142 ( 23 ) page: 10261 - 10266   2020.6

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society (ACS)  

    DOI: 10.1021/jacs.0c03097

    Web of Science

  5. Catalytic transformation of functionalized carboxylic acids using multifunctional rhenium complexes

    Masayuki Naruto, Santosh Agrawal, Katsuaki Toda, Susumu Saito

    SCIENTIFIC REPORTS   Vol. 7   2017.6

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NATURE PUBLISHING GROUP  

    Carboxylic acids (CAs) are one of the most ubiquitous and important chemical feedstocks available from biorenewable resources, CO2, and the petrochemical industry. Unfortunately, chemoselective catalytic transformations of CHnCO2H (n = 1-3) groups into other functionalities remain a significant challenge. Herein, we report rhenium(V) complexes as extremely effective precatalysts for this purpose. Compared to previously reported heterogeneous and homogeneous catalysts derived from high- or low-valent metals, the present method involves a alpha-C-H bond functionalization, a hydrogenation, and a hydrogenolysis, which affords functionalized alcohols with a wide substrate scope and high chemoselectivity under relatively mild reaction conditions. The results represent an important step toward a paradigm shift from 'low-valent' to 'high-valent' metal complexes by exploring a new portfolio of selective functional group transformations of highly oxygenated organic substrates, as well as toward the exploitation of CAs as a valuable biorenewable feedstock.

    DOI: 10.1038/s41598-017-03436-y

    Web of Science

  6. Multifaceted catalytic hydrogenation of amides via diverse activation of a sterically confined bipyridine-ruthenium framework

    Takashi Miura, Masayuki Naruto, Katsuaki Toda, Taiki Shimomura, Susumu Saito

    SCIENTIFIC REPORTS   Vol. 7   2017.5

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NATURE PUBLISHING GROUP  

    Amides are ubiquitous and abundant in nature and our society, but are very stable and reluctant to salt-free, catalytic chemical transformations. Through the activation of a "sterically confined bipyridineruthenium (Ru) framework (molecularly well-designed site to confine adsorbed H-2 in)" of a precatalyst, catalytic hydrogenation of formamides through polyamide is achieved under a wide range of reaction conditions. Both C=O bond and C-N bond cleavage of a lactam became also possible using a single precatalyst. That is, catalyst diversity is induced by activation and stepwise multiple hydrogenation of a single precatalyst when the conditions are varied. The versatile catalysts have different structures and different resting states for multifaceted amide hydrogenation, but the common structure produced upon reaction with H-2, which catalyzes hydrogenation, seems to be "H-Ru-N-H."

    DOI: 10.1038/s41598-017-01645-z

    Web of Science

  7. Cationic mononuclear ruthenium carboxylates as catalyst prototypes for self-induced hydrogenation of carboxylic acids Reviewed

    Masayuki Naruto, Susumu Saito

    NATURE COMMUNICATIONS   Vol. 6   page: 8140   2015.8

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:NATURE PUBLISHING GROUP  

    Carboxylic acids are ubiquitous in bio-renewable and petrochemical sources of carbon. Hydrogenation of carboxylic acids to yield alcohols produces water as the only byproduct, and thus represents a possible next generation, sustainable method for the production of these alternative energy carriers/platform chemicals on a large scale. Reported herein are molecular insights into cationic mononuclear ruthenium carboxylates ([Ru(OCOR)](+)) as prototypical catalysts for the hydrogenation of carboxylic acids. The substrate-derived coordinated carboxylate was found to function initially as a proton acceptor for the heterolytic cleavage of dihydrogen, and subsequently also as an acceptor for the hydride from [Ru-H](+), which was generated in the first step (self-induced catalysis). The hydrogenation proceeded selectively and at high levels of functional group tolerance, a feature that is challenging to achieve with existing heterogeneous/homogeneous catalyst systems. These fundamental insights are expected to significantly benefit the future development of metal carboxylate-catalysed hydrogenation processes of bio-renewable resources.

    DOI: 10.1038/ncomms9140

    Web of Science

  8. Iron/Amino Acid Catalyzed Direct N-Alkylation of Amines with Alcohols Reviewed

    Yingsheng Zhao, Siong Wan Foo, Susumu Saito

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 50 ( 13 ) page: 3006 - 3009   2011

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-V C H VERLAG GMBH  

    DOI: 10.1002/anie.201006660

    Web of Science

  9. RhI-catalyzed Hydration of Organonitriles Under Ambient Conditions Reviewed

    Akihiro Goto, Kohei Endo, Susumu Saito

    Angew. Chem. Int. Ed.   Vol. 47   page: 3607-3609   2008

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  10. Phosphorus-based organocatalysis for dehydrative cyclization of N-(2-hydroxyethyl)amides into 2-oxazolines. Reviewed

    (10) Farzaneh Soleymani Movahed, Siong Wan Foo, Shogo Mori, Saeko Ogawa, Susumu Saito*

    J. Org. Chem.   Vol. 87 ( 1 ) page: 243 - 257   2021.12

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.joc.1c02318

  11. Highly durable, self-photosentisized mononuclear ruthenium catalyst for CO2 reduction. Invited Reviewed

    (11) Kenji Kamada, Hiroko Okuwa, Taku Wakabayshi, Keita Sekizawa, Shunsuke Sato, Takeshi Morikawa, Jieun Jung,* Susumu Saito*

    Synlett   Vol. 33   page: A - E   2021.11

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/a-1709-0280

  12. Recent advances in light-driven C–C bond formation via carbon dioxide activation Invited Reviewed

    Synthesis   Vol. 53   page: 3263 - 3278   2021.8

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1055/a-1577-5947

  13. Preparation of platinum nanoparticle catalyst closely locating near photocatalyst titanium oxide and its catalytic activity to synthesize ethers from benzyl alcohols Reviewed

    Yuki Wada, Toshiki, Akiyama, Kazuo Harada, Tetsuo Honma, Hiroshi Naka, Susumu Saito, Mitsuhiro Arisawa

    RSC Adv.   Vol. 11   page: 22230 - 22237   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d1ra00988e

  14. Development of Effective Bidentate Diphosphine Ligands of Ruthenium Catalysts toward Practical Hydrogenation of Carboxylic Acids Reviewed

    Shota Yoshioka, Ke Wen, Susumu Saito

    Bulletin of the Chemical Society of Japan     2021.3

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Chemical Society of Japan  

    DOI: 10.1246/bcsj.20210023

  15. Tris(o-phenylenedioxy)cyclotriphosphazene as a Promoter for the Formation of Amide Bonds Between Aromatic Acids and Amines Invited Reviewed

    Susumu Saito, Farzaneh Soleymani Movahed, Dinesh N. Sawant, Dattatraya B. Bagal

    Synthesis   Vol. 52 ( 21 ) page: 3253 - 3262   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Georg Thieme Verlag KG  

    The atom-efficient formation of amide bonds has emerged as a top-priority research field in organic synthesis, as amide bonds constitute the backbones of proteins and represent an important structural motif in drug molecules. Currently, the increasing demand for novel discoveries in this field has focused substantial attention on this challenging subject. Herein, the degradable 1,3,5-triazo-2,4,6-triphosphorine (TAP) motif is presented as a new condensation system for the dehydrative formation of amide bonds between diverse combinations of aromatic carboxylic acids and amines. The underlying reaction mechanism was investigated, and potential catalyst intermediates were characterized using 31P NMR spectroscopy and ESI mass spectrometry.

    DOI: 10.1055/s-0040-1707174

    Web of Science

  16. Development of Catalytic Reduction of Renewable Carbon Resources Using Well-Elaborated Organometallic Complexes with PNNP Tetradentate Ligands Invited Reviewed

    Shota Yoshioka, Jieun Jung, Susumu Saito

    Journal of Synthetic Organic Chemistry, Japan   Vol. 78 ( 9 ) page: 856 - 866   2020.9

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Society of Synthetic Organic Chemistry, Japan  

    DOI: 10.5059/yukigoseikyokaishi.78.856

  17. Catalytic Hydrogenation of N‐protected α‐Amino Acids Using Ruthenium Complexes with Monodentate Phosphine Ligands Invited Reviewed

    Akari Saito, Shota Yoshioka, Masayuki Naruto, Susumu Saito

    Advanced Synthesis & Catalysis   Vol. 362 ( 2 ) page: 424 - 429   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Wiley  

    DOI: 10.1002/adsc.201901298

    Web of Science

    Other Link: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/adsc.201901298

  18. Pd/TiO2-Photocatalyzed Self-Condensation of Primary Amines To Afford Secondary Amines at Ambient Temperature Reviewed

    Wang Lyu-Ming, Kobayashi Kensuke, Arisawa Mitsuhiro, Saito Susumu, Naka Hiroshi

    ORGANIC LETTERS   Vol. 21 ( 2 ) page: 341-344 - 344   2019.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.8b03271

    Web of Science

  19. Catalytic hydrogenation of carboxylic acids using low-valent and high-valent metal complexes Reviewed

    Yoshioka Shota, Saito Susumu

    CHEMICAL COMMUNICATIONS   Vol. 54 ( 95 )   2018.12

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c8cc06543h

    Web of Science

  20. N-Alkylation of functionalized amines with alcohols using a copper-gold mixed photocatalytic system Reviewed

    Lyu-Ming Wang, Yuna Morioka, Kellie Jenkinson, Andrew E. H. Wheatley, Susumu Saito, Hiroshi Naka

    Scientific Reports   Vol. 8 ( 1 )   2018.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Nature Publishing Group  

    Direct functionalization of amino groups in complex organic molecules is one of the most important key technologies in modern organic synthesis, especially in the synthesis of bio-Active chemicals and pharmaceuticals. Whereas numerous chemical reactions of amines have been developed to date, a selective, practical method for functionalizing complex amines is still highly demanded. Here we report the first late-stage N-Alkylation of pharmaceutically relevant amines with alcohols at ambient temperature. This reaction was achieved by devising a mixed heterogeneous photocatalyst in situ prepared from Cu/TiO2 and Au/TiO2. The mixed photocatalytic system enabled the rapid N-Alkylation of pharmaceutically relevant molecules, the selective mono-and di-Alkylation of primary amines, and the non-symmetrical dialkylation of primary amines to hetero-substituted tertiary amines.

    DOI: 10.1038/s41598-018-25293-z

    Web of Science

    Scopus

  21. Photocatalytic N-Methylation of Amines over Pd/TiO2 for the Functionalization of Heterocycles and Pharmaceutical Intermediates Reviewed

    Wang Lyu-Ming, Jenkinson Kellie, Wheatley Andrew E. H, Kuwata Keiko, Saito Susumu, Naka Hiroshi

    ACS SUSTAINABLE CHEMISTRY & ENGINEERING   Vol. 6 ( 11 ) page: 15419-15424 - 15424   2018.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acssuschemeng.8b03855

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  22. Diboron-Catalyzed Dehydrative Amidation of Aromatic Carboxylic Acids with Amines Reviewed

    Sawant Dinesh N, Bagal Dattatraya B, Ogawa Saeko, Selvam Kaliyamoorthy, Saito Susumu

    ORGANIC LETTERS   Vol. 20 ( 15 ) page: 4397-4400   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.8b01480

    Web of Science

  23. N-Alkylation of functionalized amines with alcohols using a copper-gold mixed photocatalytic system (vol 8 , 6931, 2018) Reviewed

    Wang Lyu-Ming, Morioka Yuna, Jenkinson Kellie, Wheatley Andrew E. H., Saito Susumu, Naka Hiroshi

    SCIENTIFIC REPORTS   Vol. 8   2018.6

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    Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-018-27270-y

    Web of Science

  24. Photocatalytic hydrogenolysis of allylic alcohols for rapid access to platform chemicals and fine chemicals Invited Reviewed

    Yuki Takada, Joaquim Caner, Hiroshi Naka, Susumu Saito

    Pure and Applied Chemistry   Vol. 90 ( 1 ) page: 167 - 174   2018.1

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    Language:English   Publishing type:Research paper (international conference proceedings)   Publisher:Walter de Gruyter GmbH  

    A brief account of our recent work on the chemo-, regio- and stereoselective photocatalytic hydrogenolysis of allylic alcohols to alkenes promoted by palladium-loaded titanium oxide (Pd/TiO2) photocatalysts is presented. Since methanol is employed as the reducing agent, the method does not involve stoichiometric generation of salt waste. The photocatalytic hydrogenolysis proceeds at room temperature, and is compatible with the presence of functional groups such as C=C double bonds and hydroxyl groups at non-allylic positions. The regioselectivity is predictable: the hydrogen atom is predominantly incorporated into the sterically less hindered carbon atom of the allylic moiety. This protocol should provide straightforward green access to a range of platform chemicals (exemplified by the two-step synthesis of propylene from glycerol) and fine chemicals [e.g. (S)-(+)-lavandulol from (R)-(-)-carvone] without the need for protection/deprotection steps.

    DOI: 10.1515/pac-2017-0501

    Web of Science

    Scopus

  25. Photocatalytic Transfer Hydrogenolysis of Allylic Alcohols on Pd/TiO2: A Shortcut to (S)-(+)-Lavandulol

    Yuki Takada, Joaquim Caner, Selvam Kaliyamoorthy, Hiroshi Naka, Susumu Saito

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 23 ( 71 ) page: 18025 - 18032   2017.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-V C H VERLAG GMBH  

    We report herein a regio- and stereoselective photocatalytic hydrogenolysis of allylic alcohols to form unsaturated hydrocarbons employing a palladium(II)-loaded titanium oxide; the reaction proceeds at room temperature under light irradiation without stoichiometric generation of salt wastes. Olefin and saturated alcohol moieties tolerated the reaction conditions. Hydrogen atoms were selectively incorporated into less sterically congested carbons of the allylic functionalities. This protocol allowed a short-step synthesis of (S)-(+)-lavandulol from (R)-(-)-carvone by avoiding otherwise necessary protection/deprotection steps.

    DOI: 10.1002/chem.201704099

    Web of Science

  26. Dehydrogenation of Primary Aliphatic Alcohols by Au/TiO2 Photocatalysts Reviewed

    Masaki Shibata, Ryoko Nagata, Susumu Saito, Hiroshi Naka

    CHEMISTRY LETTERS   Vol. 46 ( 4 ) page: 580 - 582   2017.4

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:CHEMICAL SOC JAPAN  

    Dehydrogenation reaction of primary aliphatic alcohols to aldehydes and molecular hydrogen was achieved under UV-vis light irradiation in the presence of gold-loaded titanium dioxide (Au/TiO2) photocatalysts.

    DOI: 10.1246/cl.161195

    Web of Science

  27. Investigation of the Corey Bromolactamization with N-Functionalized Allylamines Reviewed

    Adrian Schulte, Simon Janich, Ernst-Ulrich Wuerthwein, Susumu Saito, Bernhard Wuensch

    JOURNAL OF HETEROCYCLIC CHEMISTRY   Vol. 53 ( 6 ) page: 1827 - 1837   2016.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WILEY-BLACKWELL  

    N-Allylamines were employed for the diastereoselective synthesis of 8-bromo-substituted, cis-configured perhydroquinoxalines and beta-bromoalcohols. The yield and constitution of the products depend considerably on the functionalization of the allylic N-atom. Herein the reaction of glycine-derived cyclohex-2-enamines 5 under bromolactamization conditions (LiOtBu, NBS) is reported. Methyl carbamate 5a led diastereoselectively to the cis-configured perhydroquinoxaline 6a, whereas the amides 5b and 5c provided cis, trans-configured -bromoalcohols 7b and 7c. Based on high level theoretical calculations (DFT) factors controlling the cyclization of lithiated intermediates and the relative energies of possible products are discussed.

    DOI: 10.1002/jhet.2493

    Web of Science

  28. Versatile Ruthenium Complex "RuPCY" for Directed Catalytic Hydrogen Management in Organic Synthesis Invited Reviewed

    Yuki Takada, Megumi Iida, Kazuki Iida, Takashi Miura, Susumu Saito

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   Vol. 74 ( 11 ) page: 1078 - 1089   2016.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:SOC SYNTHETIC ORGANIC CHEM JPN  

    The ruthenium (Ru) precatalyst complex dichlorobis[2-[(dicyclohexylphosphino-kappa P)methyl]pyridine- kappa N]ruthenium(II) (RuPCY), first developed by us, was shown to be useful not only for the catalytic hydrogenation of inert carboxylic acid derivatives including amides and esters, but also for the catalytic dehydrogenation of primary (1 degrees) and secondary (2 degrees) alcohols and subsequent reactions. RuPCY is versatile, and different Ru catalysts derived therefrom are quite useful for realizing a variety of indiscrete/discrete catalytic hydrogen management (HyMA) reactions. The sequential use of different starting materials and different catalysts (all derived from RuPCY) permits otherwise challenging orthogonal HyMA processes. This accommodates, for example, a salt-free access and/or shortcut to synthetic intermediates of pharmaceutically important substances such as donepezil (Aricept (R)) and atorvastatin (Lipitor (R)).

    Web of Science

  29. Synthesis of morphan derivatives with additional substituents in 8-position Reviewed

    Janine Stefaowitz, Dirk Schepmann, Constantin Daniliuc, Susumu Saito, Bernhard Wuensch

    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES   Vol. 71 ( 10 ) page: 1057 - 1069   2016.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WALTER DE GRUYTER GMBH  

    The morphan system (2-azabicyclo[3.3.1]no-nane) as a substructure of morphine is of major interest in medicinal chemistry. Herein, the synthesis of morphan derivatives with additional substituents at the propano bridge is reported. In order to avoid the isolation of the smelly and volatile nitrile 6 and the very polar primary amine 9, an efficient one-pot, three-step sequential transformation of the mesylate 5 into amides 10 was developed. The key step of the synthesis was the stereoselective intramolecular opening of the epoxides 11a-d leading to the exo-configured 8-hydroxymorphans 12a-d. The configuration of the exo-configured hydroxymorphan 12d bearing the kappa- and sigma-pharmacophoric 3,4-dichlorophenylacetyl moiety was inverted by oxidation and stereoselective reduction. An X-ray crystal structure analysis of the benzamide 12c confirmed the relative configuration of the hydroxymorphans 12a-d and 14d.

    DOI: 10.1515/znb-2016-0129

    Web of Science

  30. Stereoselective Synthesis of cis,cis-Configured Perhydroquinoxaline-5-Carbonitrile from Cyclohex-2-en-1-ol Reviewed

    Adrian Schulte, Susumu Saito, Bernhard Wuensch

    JOURNAL OF HETEROCYCLIC CHEMISTRY   Vol. 53 ( 2 ) page: 533 - 536   2016.3

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    cis,cis-Configured perhydroquinoxaline-5-carbonitrile 10 was synthesized stereoselectively by ditosylation of trans,cis-2,3-dihydroxycyclohexane-1-carbonitrile 4 and subsequent reaction with ethylenediamine. The diol precursor 4 was stereoselectively obtained by regioselective opening of the epoxide 3 with KCN in water avoiding hazardous Et2AlCN.

    DOI: 10.1002/jhet.2322

    Web of Science

  31. N-Methylation of Amines with Methanol at Room Temperature Reviewed

    Vasily N. Tsarev, Yuna Morioka, Joaquim Caner, Qing Wang, Richiro Ushimaru, Akihiko Kudo, Hiroshi Naka, Susumu Saito

    ORGANIC LETTERS   Vol. 17 ( 10 ) page: 2530 - 2533   2015.5

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    N-Methylation of amines with methanol proceeds at room temperature in the presence of a silver-loaded titanium dioxide (Ag/TiO2) photocatalyst under UV-vis light irradiation. This method allows facile synthesis/isolation of N-methylamines bearing various functional groups including N-benzyl, N-allyl, N-Boc, hydroxyl, ether, acetal, carboxamide, formamide, and olefin groups.

    DOI: 10.1021/acs.orglett.5b01063

    Web of Science

  32. One-step synthesis of patterned polymer brushes by photocatalytic microcontact printing Reviewed

    Friederike Kettling, Benjamin Vonhoeren, Jennifer A. Krings, Susumu Saito, Bart Jan Ravoo

    CHEMICAL COMMUNICATIONS   Vol. 51 ( 6 ) page: 1027 - 1030   2015

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    A novel method to prepare microstructured polymer brushes using TiO2 nanoparticles and photocatalytic microcontact printing is described. It is shown that ethanol amine can be polymerized to linear polyethyleneimine (PEI) driven by the photocatalytic action of TiO2. Upon UV irradiation during microcontact printing of ethanol amine with a stamp coated with TiO2 nanoparticles, patterned polymer brushes with a length of around 50 nm are obtained.

    DOI: 10.1039/c4cc08646e

    Web of Science

  33. Hydration of nitriles to amides by a chitin-supported ruthenium catalyst

    Matsuoka Aki, Isogawa Takahiro, Morioka Yuna, Knappett Benjamin R, Wheatley Andrew E. H, Saito Susumu, Naka Hiroshi

    RSC ADVANCES   Vol. 5 ( 16 ) page: 12152-12160   2015

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    DOI: 10.1039/c4ra15682j

  34. Bromolactamization: Key Step in the Stereoselective Synthesis of Enantiomerically Pure, cis-Configured Perhydropyrroloquinoxalines Reviewed

    Adrian Schulte, Xingci Situ, Susumu Saito, Bernhard Wuensch

    CHIRALITY   Vol. 26 ( 12 ) page: 793 - 800   2014.12

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    Compounds based on the pyrroloquinoxaline system can interact with serotonin 5-HT3, cannabinoid CB1, and -opioid receptors. Herein, a chiral pool synthesis of diastereomerically and enantiomerically pure bromolactam (S,R,R,R)-14A is presented. Introduction of the cyclohexenyl ring at the N-atom of (S)-proline derivatives 8 or methyl (S)-pyroglutamate (12) led to the N-cyclohexenyl substituted pyrrolidine derivatives 4 and 13, respectively. All attempts to cyclize the (S)-proline derivatives 4 with a basic pyrrolidine N-atom via [3+2] cycloaddition, aziridination, or bromolactamization failed. Fast aromatization occurred during treatment of cyclohexenamines under halolactamization conditions. In contrast, reaction of a 1:1 mixture of diastereomeric pyroglutamates (S,R)-13bA and (S,S)-13bB with (LiOBu)-Bu-t and NBS provided the tricyclic bromolactam (S,R,R,R)-14A with high diastereoselectivity from (S,R)-13bA, but did not transform the diastereomer (S,S)-13bB. The different behavior of the diastereomeric pyroglutamates (S,R)-13bA and (S,S)-13bB is explained by different energetically favored conformations. Chirality 26:793-800, 2014. (c) 2014 Wiley Periodicals, Inc.

    DOI: 10.1002/chir.22350

    Web of Science

  35. Stereoselective Synthesis of cis,cis-Configured Vicinal Triamines Reviewed

    Adrian Sehulte, Susumu Saito, Bernhard Wuensch

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY   ( 26 ) page: 5749 - 5756   2014.9

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    The first stereoselective synthesis of a cis, cis-configured vicinal triamine was achieved, starting from N-cyclohexenylpyrrolidone (10). The reaction sequence consists of the stereoselective construction of the trans-configured 1,3-diamide 14, trans-to-cis isomerization via enols or enamines, and subsequent highly stereoselective reduction of the intermediate imine 17D to the amine 18A. The postulated reaction pathway explains the observed stereoconvergence and is supported by calculation of the heats of formation of its intermediates at the PM3 level. LiAlH4 reduction of 18A yielded the tetracyclic aminal 19, which was converted into the pyrrolidinylquinoxaline 7, which showed low to moderate affinity towards. and sigma(1) receptors.

    DOI: 10.1002/ejoc.201402685

    Web of Science

  36. A Route to propylene from renewable allyl alcohol by photocatalytic transfer hydrogenolysis Reviewed

    Joaquim Caner, Zijun Liu, Yuki Takada, Akihiko Kudo, Hiroshi Naka, Susumu Saito

    Catal. Sci. Technol.   Vol. 4 ( 11 ) page: 4093–4098   2014

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  37. Catalytic fluoride triggers dehydrative oxazolidinone synthesis from CO2 Reviewed

    Yuki Takada, Siong Wan Foo, Yusuke Yamazaki, Susumu Saito

    RSC ADVANCES   Vol. 4 ( 92 ) page: 50851 - 50857   2014

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    Herein, catalytic fluoride (F-) is demonstrated to be a trigger for dehydrative immobilization of atmospheric pressure CO2, such that reaction of CO2 with beta-amino alcohols derived from natural amino acids gives optically pure oxazolidinones in high yields. A synergistic combination of fluoride and organosilicon agents (e.g., Bu4NF + Ph3SiF or siloxanes) enhances the catalytic activity and functional group compatibility. This system lies at the interface between homogenous and heterogeneous catalysis, and may prove useful for the development of recoverable/reusable siloxane-based CO2 immobilization materials.

    DOI: 10.1039/c4ra09609f

    Web of Science

  38. Synthesis of propylene from renewable allyl alcohol by photocatalytic transfer hydrogenolysis

    Caner Joaquim, Liu Zijun, Takada Yuki, Kudo Akihiko, Naka Hiroshi, Saito Susumu

    CATALYSIS SCIENCE & TECHNOLOGY   Vol. 4 ( 11 ) page: 4093-4098   2014

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    DOI: 10.1039/c4cy00329b

  39. Dehydrative synthesis of chiral oxazolidinones catalyzed by alkali metal carbonates under low pressure of CO2 Reviewed

    Siong Wan Foo, Yuki Takada, Yusuke Yamazaki, Susumu Saito

    TETRAHEDRON LETTERS   Vol. 54 ( 35 ) page: 4717 - 4720   2013.8

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    Dehydrative synthesis of oxazolidinones from amino alcohols and CO2 was achieved in the presence of alkali metal carbonates such as Cs2CO3 as catalyst. It is noteworthy that 1 atm of CO2 is enough for the reaction to proceed and no special dehydrating agent is required in this system. A mechanstic study showed that the OH of amino alcohol acts as nucleophile and the OH in the carbamic acid moiety is liberated during the cyclization process. (C) 2013 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.tetlet.2013.06.100

    Web of Science

  40. Catalytic hydrogenation of unactivated amides enabled by hydrogenation of catalyst precursor Reviewed

    Takashi Miura, Ingmar E. Held, Shunsuke Oishi, Masayuki Naruto, Susumu Saito

    TETRAHEDRON LETTERS   Vol. 54 ( 21 ) page: 2674 - 2678   2013.5

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    A general method for catalytic hydrogenation of unactivated amides was achieved. During the catalyst induction period, a novel structural change was observed involving full hydrogenation of the interior unsaturated bonds of the pyridines of the Ru-containing catalyst precursor. Based on this observation, the mechanism of amide hydrogenation may involve a two-step pathway, wherein the Ru catalyst having an H-Ru-N-H functionality is generated in the first step, followed by the amide carbonyl group interacting with the outer, rather than the inner, sphere of the Ru catalyst. (c) 2013 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.tetlet.2013.03.047

    Web of Science

  41. The Dual Role of Ruthenium and Alkali Base Catalysts in Enabling a Conceptually New Shortcut to N-Unsubstituted Pyrroles through Unmasked alpha-Amino Aldehydes Reviewed

    Kazuki Iida, Takashi Miura, Junki Ando, Susumu Saito

    ORGANIC LETTERS   Vol. 15 ( 7 ) page: 1436 - 1439   2013.4

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    A virtually salt-free and straightforward bimolecular assembly giving N-unsubstituted pyrroles through fully unmasked a-amino aldehydes, which was enabled by the dual effects of a catalytic ruthenium complex and an alkali metal base, is reported. Either solvent-free or acceptorless dehydrogenation facilitates high atom, step, and pot economy, which are otherwise difficult to achieve in multistep operations involving protection/deprotection.

    DOI: 10.1021/ol4001262

    Web of Science

  42. Reaction of an "Invisible" Frustrated N/B Lewis Pair with Dihydrogen Reviewed

    Sina Schwendemann, Shunsuke Oishi, Susumu Saito, Roland Froehlich, Gerald Kehr, Gerhard Erker

    CHEMISTRY-AN ASIAN JOURNAL   Vol. 8 ( 1 ) page: 212 - 217   2013.1

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    D-(+)-Camphor forms the enamine 2 with piperidine. Compound 2 adds HB(C6F5)(2) at the enamine carbon atom C3 to form a Lewis acid/Lewis base adduct (exo-/endo-isomers of 3). Exposure of 3 to dihydrogen (2.5 bar, room temperature) leads to heterolytic splitting of H-2 to form the H+/H- addition products (4, two diastereoisomers) of the "invisible" frustrated Lewis pairs (5, two diastereoisomers) that were apparently generated in situ by enamine hydroboration under equilibrium conditions.

    DOI: 10.1002/asia.201200776

    Web of Science

  43. Redox-selective Generation of Aldehydes and H2 from Alcohols under Visible Light Reviewed

    Zijun Liu, Joaquim Caner, Akihiko Kudo, Hiroshi Naka, *Susumu Saito

    Chem. Eur. J.   Vol. 19   page: 9452–9456   2013

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  44. Acetals of N,N-dimethylformamides: Ambiphilic behavior in converting carbon dioxide to dialkyl carbonates Reviewed

    Yuki Takada, Aki Matsuoka, Ya Du, Hiroshi Naka, Susumu Saito

    Chemistry Letters   Vol. 42 ( 2 ) page: 146 - 147   2013

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    Carbon dioxide is immobilized into dialkyl carbonate using acetals of N,N-dimethylformamide under atmospheric pressure. No special treatment with tailor-made catalysts is needed. Use of dimethyl sulfoxide as a solvent is critical. An ambiphilic mechanism is proposed for the direct synthesis of dialkyl carbonates from acetals and carbon dioxide. © 2013 The Chemical Society of Japan.

    DOI: 10.1246/cl.2013.146

    Scopus

  45. Catalytic Hydrogenation of Unactivated Amides Using Molecular Catalyst Surface Derived from Ruthenium Complex Invited Reviewed

    Takashi Miura, Ingmar E. Held, Shunsuke Oishi, Susumu Saito

    Catalysts and Catalysis: Special Issue: Special Issue: Recent Trend in Catalytic Chemicals Synthesis Using Hydrogen   Vol. 54 ( 7 ) page: 455–459   2012.12

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  46. Aldol condensation of amides using phosphazene-based catalysis Reviewed

    Siong Wan Foo, Shun Oishi, Susumu Saito

    TETRAHEDRON LETTERS   Vol. 53 ( 40 ) page: 5445 - 5448   2012.10

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    We have developed a new method for the direct aldol condensation of unactivated amides using 1,3,5-triazo-2,4,6-triphosphorine-2,2,4,4,6,6-hexachloride (TAPC)-based phosphorous/SO42- catalysis. The SO42- species in a reaction mixture enhances the reaction rate of the catalysis. In principle, no metal sources are required for the generation of the catalyst, and there is no requirement for the use of stoichiometric quantities of an acid or base. This catalyst system is operative under relatively acidic conditions. One major advantage of carrying out the reaction under acidic conditions is that both aldehydes and acetals are capable of undergoing carbon-carbon bond formation at the alpha-carbon of amide carbonyl groups through dehydration. (C) 2012 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.tetlet.2012.07.129

    Web of Science

  47. Double Molecular Recognition with Aminoorganoboron Complexes: Selective Alcoholysis of beta-Dicarbonyl Derivatives Reviewed

    Shunsuke Oishi, Susumu Saito

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 51 ( 22 ) page: 5395 - 5399   2012

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    DOI: 10.1002/anie.201200304

    Web of Science

  48. Selective N-Alkylation of Amines with Alcohols by Using Non-Metal-Based Acid-Base Cooperative Catalysis Reviewed

    Ya Du, Shunsuke Oishi, Susumu Saito

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 17 ( 44 ) page: 12262 - 12267   2011.10

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    DOI: 10.1002/chem.201102446

    Web of Science

  49. Cu-I/H-2/NaOH-Catalyzed Cross-Coupling of Two Different Alcohols for Carbon-Carbon Bond Formation: "Borrowing Hydrogen"? Reviewed

    Takashi Miura, Osamu Kose, Feng Li, Sun Kai, Susumu Saito

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 17 ( 40 ) page: 11146 - 11151   2011.9

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    DOI: 10.1002/chem.201101752

    Web of Science

  50. One-Pot Nitrile Aldolization/Hydration Operation Giving beta-Hydroxy Carboxamides Reviewed

    Akihiro Goto, Hiroshi Naka, Ryoji Noyori, Susumu Saito

    CHEMISTRY-AN ASIAN JOURNAL   Vol. 6 ( 7 ) page: 1740 - 1743   2011.7

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    DOI: 10.1002/asia.201000921

    Web of Science

  51. N Alkylation of Amines with Alcohols by Using Non Metal Based Acid/base Cooperative Catalysis Reviewed

    Ya Du, Shunsuke Oishi, Susumu Saito

    Chem. Eur. J.   Vol. 17   page: 12262–12267   2011

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  52. Synthesis of carbonates directly from 1 atm CO2 and alcohols using CH2Cl2 Reviewed

    Yusuke Yamazaki, Kasumi Kakuma, Ya Du, Susumu Saito

    TETRAHEDRON   Vol. 66 ( 51 ) page: 9675 - 9680   2010.12

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    We introduced here a new one-pot, general procedure for the preparation of dialkyl carbonates from alcohols in a straightforward fashion under 1 atm pressure of CO2 using Cs2CO3 and CH2Cl2 as key reagents. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.tet.2010.10.051

    Web of Science

  53. Cross-coupling reaction of alcohols for carbon-carbon bond formation using pincer-type NHC/palladium catalysts Reviewed

    Osamu Kose, Susumu Saito

    ORGANIC & BIOMOLECULAR CHEMISTRY   Vol. 8 ( 4 ) page: 896 - 900   2010

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    A cross-coupling reaction of different alcohols was achieved using a pincer-type NHC/PdBr complex as the catalyst precursor, and the reaction, under either Ar or H(2) gas, displayed a broad substrate scope with respect to both primary and secondary alcohol components, with high alcohol product selectivity.

    DOI: 10.1039/b914618k

    Web of Science

  54. Synthesis of a Silanol-substituted Proline Analog as Organocatalyst Reviewed

    Daniel Kracht, Susumu Saito, Roland Froehlich, Bernhard Wuensch

    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES   Vol. 64 ( 10 ) page: 1169 - 1175   2009.10

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    A proline-derived silanol, was designed as a novel potential organocatalyst, and synthesized starting from the tetrazole 3. The central idea was the combination of all acidic (tetrazole) and a basic functionality (pyrrolidine) with a silanol moiety in the same molecule. The synthesis of 7 was performed ill four reaction steps starting with the tetrazole 3. In the solid state (X-ray crystal Structure analysis) the crucial functional groups show a favorable orientation. A chiral HPLC method and a chiral capillary electrophoresis method have been established for the investigation of the kinetic resolution of the racemic alcohols 9 and 11. Acetylation reactions of alcohols were not accelerated by the organocatalyst 7, and the produced ee values were rather low.

    Web of Science

  55. Importance of Open Structure of Nonmetal Based Catalyst in Hydrogen Bond Promoted Methanolysis of Activated Amide: Structure Dynamics between Monomer and Dimer Enabling Recombinant Covalent, Dative, and Hydrogen Bonds Reviewed

    Shunsuke Oishi, Junichi Yoshimoto, Susumu Saito

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 131 ( 25 ) page: 8748 - +   2009.7

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    We disclosed structural dynamics hidden behind a series of aminoorganoboron (AOB) compounds that involved a recombinant of covalent, dative, and hydrogen bonds. A combination process occurred via reorganizing elements and bonds between the two major structures (open and closed), which were chemically switchable through precise adjustment of either acidic or basic conditions. The structural dynamics favoring an open structure seem to be more important for catalysis, as represented by methanolysis of activated amides.

    DOI: 10.1021/ja9029494

    Web of Science

  56. Synthesis of 1,4-Diazabicyclo[3.3.1]nonan-6-ones Reviewed

    Daniel Kracht, Susumu Saito, Bernhard Wuensch

    AUSTRALIAN JOURNAL OF CHEMISTRY   Vol. 62 ( 12 ) page: 1684 - 1689   2009

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    1,4-Diazabicyclo[3.3.1] nonanes (aza-morphans) represent conformationally constrained piperazine derivatives. Herein, we report a six-step synthesis of the benzyl and allyl substituted bicyclic ketones 3a and 3b, which represent interesting building blocks for the synthesis of conformationally restricted receptor ligands. The key steps of the synthesis are the regioselective addition of ethyl acrylate to the piperazine 8, the sodium hexamethyldisilazide-induced Dieckmann cyclization of the diesters 10, and the decarboxylation of the enol esters 11 with dilute HCl. The complete sequence is only successful when a benzyl (10a) or allyl moiety (10b) is attached to N-1, since the tosyl derivative 10f failed to give a Dieckmann cyclization product, and the decarboxylation failed with the acyl derivatives 11c and 11d.

    DOI: 10.1071/CH09206

    Web of Science

  57. Aqua-aminoorganoboron Catalyst: Engineering Single Water Molecule to Act as an Acid Catalyst in Nitro Aldol Reaction Reviewed

    Junichi Yoshimoto, Christian A. Sandoval, Susumu Saito

    CHEMISTRY LETTERS   Vol. 37 ( 12 ) page: 1294 - 1295   2008.12

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    We have disclosed the catalytic potential hidden behind a series of aqua-aminoorganoboron compounds in the formation and reaction of nitronate species. The pivotal role of a single-coordinated water molecule in the catalyst was demonstrated by comparison with the D2O-analogue. The present results provide a new strategy for the design of metal-free catalysts which function via elaborative hydrogen-bonding networks involving water.

    DOI: 10.1246/cl.2008.1294

    Web of Science

  58. Development of organocatalysis based on the molecular design of pyrrolidine-bronsted acid catalysts Invited Reviewed

    Susumu Saito, Norie Momiyama, Hisashi Yamamoto

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   Vol. 66 ( 8 ) page: 774 - 784   2008.8

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    Proper design of amine-Bronsted acid catalysis has been shown to be effective for achieving high reactivity and selectivity in the asymmetric direct aldol reaction. During the course of this study, two principal approaches have been implemented to create a new type of catalysis: One is derived from Bronsted acid and diamine; the other is pyrrolidine with tetrazole functionality. The developed amine-Bronsted acid catalysts have been found to effectively catalyze the direct aldol reaction of aldehyde, chloral and nitrosobenzene.

    Web of Science

  59. Rh(I)-catalyzed aldol-type reaction of organonitriles under mild conditions Reviewed

    Akihiro Goto, Kohei Endo, Yu Ukai, Stephan Irle, Susumu Saito

    CHEMICAL COMMUNICATIONS   ( 19 ) page: 2212 - 2214   2008.5

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    An aldol-type reaction of organonitriles with aldehydes was catalyzed by a Rh(I)(OR) species under ambient conditions, and the reaction displayed a broad substrate scope with respect to both organonitrile and aldehyde components.

    DOI: 10.1039/b800634b

    Web of Science

  60. 山本尚先生、玉尾皓平先生に日本学士院賞―有機典型元素化合物の反応、物性の開拓に貢献 Invited

    斎藤 進、山口茂弘

    現代化学   ( 434 ) page: 13   2007

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  61. 山本尚先生、玉尾皓平先生日本学士院賞を受賞 Invited

    斎藤 進、山口茂弘

    有機合成化学協会誌   Vol. 65 ( 5 ) page: 418   2007

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  62. 有機触媒を用いる酸-塩基相互作用の制御と有機アニオン種の形成に基づく不斉合成 Invited

    斎藤 進

    月刊ファインケミカル   Vol. 36 ( 5 ) page: 64-80   2007

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  63. 東海から発信する産学官連携のトレンド Invited

    大島 康裕、斎藤 進、紫牟田 正則

    化学と工業   Vol. 59 ( 7 ) page: 784   2006

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  64. 有機触媒を用いる環境調和型合成 Invited

    斎藤 進

    化学と工業   Vol. 58 ( 9 ) page: 1041-1042   2005

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  65. Design of acid - Base catalysis for the asymmetric direct aidol reaction Invited Reviewed

    S Saito, H Yamamoto

    ACCOUNTS OF CHEMICAL RESEARCH   Vol. 37 ( 8 ) page: 570 - 579   2004.8

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    Proper design of acid-base catalysis has been shown to be effective for achieving high reactivity and selectivity in the asymmetric direct aldol reaction during the development of diamine-Bronsted acid types of catalyst. In this study, two principal approaches have been implemented to create a new type of catalysis and high catalytic efficiency: one is the creation of a highly viable acidic function within acid-base catalysts; the other is the creation of rather complicated but more cooperatively arranged hydrogen-bond networks that would be expected to stabilize a transition state, thereby promoting new reactivity and selectivity.

    DOI: 10.1021/ar030064p

    Web of Science

  66. O-nitroso aldol synthesis: Catalytic enantioselective route to alpha-aminooxy carbonyl compounds via enamine intermediate Invited Reviewed

    N Momiyama, H Torii, S Saito, H Yamamoto

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA   Vol. 101 ( 15 ) page: 5374 - 5378   2004.4

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    The approach using pyrrolidine enamine as substrate has been studied for this synthesis, and an important catalyst structural feature has been developed. After survey of pyrrolidine-based Bronsted acid catalyst, tetrazole catalyst (3f) was found to be optimal in synthesis of aminooxy carbonyl compounds in high yields, with complete enantioselectivity not only for aldehydes but also for ketones.

    DOI: 10.1073/pnas.0307785101

    Web of Science

  67. Asymmetric vinylogous direct aldol reaction using aluminum tris[2,6-bis(4-alkylphenyl)phenoxide] Reviewed

    H Takikawa, K Ishihara, S Saito, H Yamamoto

    SYNLETT   ( 4 ) page: 732 - 734   2004.3

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:GEORG THIEME VERLAG KG  

    Diastereoselective vinylogous direct aldol reaction was realized by use of chiral alpha,beta-unsaturated esters and aldehydes in the presence of aluminum tris[2,6-bis(4-alkylphenyl)phenoxide]s. The reaction involves novel 1,7-asymmetric induction and direct coupling of an alpha,beta-unsaturated ester with an aldehyde, through in situ deprotonation of the gamma-proton of the ester component by LTMP.

    DOI: 10.1055/s-2004-817761

    Web of Science

  68. Asymmetric direct aldol reaction assisted by water and a proline-derived tetrazole catalyst Reviewed

    H Torii, M Nakadai, K Ishihara, S Saito, H Yamamoto

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 43 ( 15 ) page: 1983 - 1986   2004

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    DOI: 10.1002/anie.200352724

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  69. Chiral molecular recognition by aluminum tris(2,6-diphenylphenoxide) in an asymmetric 1,4-addition Reviewed

    H Ito, T Nagahara, K Ishihara, S Saito, H Yamamoto

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 43 ( 8 ) page: 994 - 997   2004

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    DOI: 10.1002/anie.200352809

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  70. A new method for the preparation of aluminum and titanium tris(2,6-diphenylphenoxide) reagents and their application in organic synthesis Reviewed

    A Sato, A Hattori, K Ishihara, S Saito, H Yamamoto

    CHEMISTRY LETTERS   Vol. 32 ( 11 ) page: 1006 - 1007   2003.11

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    A new method for the preparation of aluminum and titanium trisphenoxides was realized using tetraallyltin or alpha-pinene as a proton-trapping agent. Thus obtained chlorotitanium reagent was converted to the corresponding cation-type reagent, which proved to be an effective catalyst for epoxide rearrangements.

    DOI: 10.1246/cl.2003.1006

    Web of Science

  71. Molecular recognition of alpha,beta-unsaturated carbonyl compounds using aluminum tris(2,6-diphenylphenoxide) (ATPH): Structural and conformational analysis of ATPH complexes and application to the selective vinylogous aldol reaction Reviewed

    S Saito, T Nagahara, M Shiozawa, M Nakadai, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 125 ( 20 ) page: 6200 - 6210   2003.5

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    Various alpha,beta-unsaturated carbonyl compounds were coordinated with aluminum tris(2,6-diphenylphenoxide) (ATPH) to give the corresponding Lewis acid-base complexes in a distinctive coordination fashion (selective coordination). ATPH recognizes carbonyl substrates and subsequently orients itself as it forms a stable complex through selective coordination with the carbonyl oxygen. Selective coordination also confers a conformational preference to each carbonyl compound under the steric and electronic influence of ATPH, which enables the vinylogous aldol reaction of alpha,beta-unsaturated carbonyl compounds to give the corresponding gamma-aldol products with different regio- and stereoselectivities.

    DOI: 10.1021/ja0205941

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  72. Diversity-based strategy for discovery of environmentally benign organocatalyst: diamine-protonic acid catalysts for asymmetric direct aldol reaction Reviewed

    M Nakadai, S Saito, H Yamamoto

    TETRAHEDRON   Vol. 58 ( 41 ) page: 8167 - 8177   2002.10

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    Fifteen different diamines (4-18) and potonic acids have been screened in the catalytic asymmetric direct aldol reaction of three different aldehydes in acetone. These initial studies demonstrated that the secondary-tertiary diamine series is effective with regard to reactivity. In contrast, the primary-tertiary diamines 13 and 14 were proved to be a superb structural module to avoid dehydration. Further investigation led us to a new procedure for the preparation of diamine catalysts for synthetic convenience. This involves diamine-diacid salt 22, which acted not only as a catalyst backbone but also as a TfOH source. Salt 22-diamine 4 catalyst thus prepared was found to exhibit higher reactivity and selectivity. (C) 2002 Elsevier Science Ltd. All rights reserved.

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  73. Asymmetric carbon-carbon coupling of phenols or anilines with aryllead triacetates Reviewed

    T Kano, Y Ohyabu, S Saito, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 124 ( 19 ) page: 5365 - 5373   2002.5

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    The asymmetric coupling of various phenol or aniline derivatives with bulky aryllead triacetates was thoroughly investigated using optically active amines, including strychnine and brucine. We found that conformationally restricted tertiary amines, as well as lithium aryloxides and molecular sieves, are essential for accelerating the rate of phenol coupling. Consequently, the reaction can be carried out at a low temperature (-40 to -20 degreesC) and gives a high degree of diastereo- and enantioselectivity. In contrast to the effectiveness of lithiation in phenol coupling, magnesation of anilines was a critical technique for aniline coupling with aryllead triacetates. Using these coupling methods, a diverse set of di-, tri, and polyaryl compounds with axial chirality can be easily obtained, and these should be useful for the construction of a variety of aryl-aryl frameworks involved in metal ligands, natural products, and artificial helical polymers.

    DOI: 10.1021/ja012287l

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  74. Nucleophilic addition of organomagnesiums to aldimines: Scandium triflate (Sc(OTf)(3)) as an effective catalyst Reviewed

    S Saito, K Hatanaka, H Yamamoto

    SYNLETT   ( 12 ) page: 1859 - 1861   2001.12

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    The 1,2-addition of organomagnesium reagents to p-methoxyphenyl(PMP)amine-derived aldimines proceeded effectively in the presence of catalytic amounts of Sc(OTf)(3).

    Web of Science

  75. Novel three-component coupling using aluminum tris(2,6-diphenylphenoxide) (ATPH): The same synthetic strategy leads to trans- and cis-jasmonates Reviewed

    Susumu Saito, Satoko Yamazaki, Hisashi Yamamoto

    Angewandte Chemie - International Edition   Vol. 40 ( 19 ) page: 3613 - 3617   2001.10

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    A one-pot three-component coupling involving organolithium reagents, ATPH·cyclopentenone complex, and dihydrofuran·BCl3 complex (see scheme) gives moderate to good yields of the products with selective formation of either the 2,3-cis or 2,3-trans isomer, depending on the nature of the lithium reagent.

    DOI: 10.1002/1521-3773(20011001)40:19<3613::AID-ANIE3613>3.0.CO;2-3

    Scopus

  76. Diamine-protonic acid catalysts for catalytic asymmetric aldol reaction Reviewed

    S Saito, M Nakadai, H Yamamoto

    SYNLETT   ( 8 ) page: 1245 - 1248   2001.8

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    Four different protonic acids and 15 diamines were screened in the catalytic asymmetric direct aldol reaction of three different aldehydes in acetone.

    Web of Science

  77. Asymmetric Mannich-type reactions with a chiral acetate: effect of Lewis acid on activation of aldimine Reviewed

    S Saito, K Hatanaka, H Yamamoto

    TETRAHEDRON   Vol. 57 ( 5 ) page: 875 - 887   2001.1

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    We introduce here a strategy that enables effective addition of lithium enolates of acetates to aldimines. The new method depends strongly on the use of ortho-alkoxy (or ortho-fluoro) aniline-derived aldimines which found to have a potential effect on the enolate addition. This scope was expanded to the asymmetric process using the chiral acetate, which has optically pure 2,6-bis(2-isopropylphenyl)-3,5-dimethylphenol as a chiral auxiliary with axial chirality. A Lewis acid additive is likely to have a complementary role in the pronounced activation of imine functionalities in the Mannich-type addition of the bulky chiral acetate. (C) 2001 Elsevier Science Ltd. All rights reserved.

    Web of Science

  78. Polyene Synthesis via Dehydration of Hydroxyenals and -enones: HfCl4_THF_2 as an Effective Catalyst for Di-, Tri-, and Tetraene Formation Reviewed

    Susumu Saito, Takashi Nagahara, Hisashi Yamamoto

    Synlett     page: 1690-1692   2001

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  79. Direct coupling of anilines with aryllead triacetates Reviewed

    S Saito, T Kano, Y Ohyabu, H Yamamoto

    SYNLETT   ( 11 ) page: 1676 - 1678   2000.11

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    The aryl-aryl coupling of aryllead triacetates at the ortho-position of anilines was achieved by simple magnesation of the aniline nitrogen.

    Web of Science

  80. Aluminum tris(2,6-diphenylphenoxide)-ArCOCl complex for nucleophilic dearomatic functionalization Reviewed

    S Saito, T Sone, M Murase, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 122 ( 41 ) page: 10216 - 10217   2000.10

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    DOI: 10.1021/ja0014382

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  81. Molecular recognition of carbonyl compounds using aluminum tris(2,6-diphenylphenoxide) (ATPH): New regio- and stereoselective alkylation of alpha,beta-unsaturated carbonyl compounds Reviewed

    S Saito, M Shiozawa, T Nagahara, M Nakadai, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 122 ( 32 ) page: 7847 - 7848   2000.8

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    DOI: 10.1021/ja000789d

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  82. Regio- and enantioselective siloxybutylation at the more hindered alpha-site of unsymmetrical ketone using chiral aluminum trisnaphthoxide Reviewed

    S Saito, M Nakadai, H Yamamoto

    SYNLETT   ( 8 ) page: 1107 - 1110   2000.8

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    A regio- and enantioselective siloxybutylation at the more hindered alpha-site of unsymmetrical dialkyl ketones was achieved to give a quarternary carbon center by the combined use of the chiral aluminum trisnaphthoxide (R)-ATBN and a base.

    Web of Science

  83. Asymmetric Mannich-type reactions of aldimines with a chiral acetate Reviewed

    S Saito, K Hatanaka, H Yamamoto

    ORGANIC LETTERS   Vol. 2 ( 13 ) page: 1891 - 1894   2000.6

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    We introduce here a strategy that enables effective addition of lithium enolates of acetates to aldimines. The new method depends strongly on the use of o-alkoxy (or o-fluoro) aniline-derived aldimines which have been found to have a potential effect on the enolate addition. This scope was expanded to the asymmetric process using the chiral acetate. A Lewis acid additive has a complementary role in the pronounced activation of imine functionalities.

    DOI: 10.1021/ol000099e

    Web of Science

  84. 実用的な金属試薬、アルミニウム Invited

    斎藤 進

    ファルマシア   Vol. 36 ( 7 ) page: 610-611   2000

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  85. Aluminum Tris(2,6-diphenylphenoxide)-ArCOCl Complex for Nucleophilic Dearomatic Functionalization Reviewed

    Susumu Saito, Toshihiko Sone, Masaaki Murase and Hisashi Yamamoto

    J. Am. Chem. Soc.   Vol. 122   page: 10216-10217   2000

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  86. Molecular Recognition of Carbonyl Compounds Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH) : New Regio- and Stereoselective Alkylation of a,b-Unsaturated Carbonyl Compounds. Reviewed

    Susumu Saito, Masahito Shiozawa, Takashi Nagahara, Masakazu Nakadai, and Hisashi Yamamoto

    J. Am. Chem. Soc.   Vol. 122   page: 7847-7848   2000

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  87. Li(I), Na(I) and K(I) Lewis Acids

    Susumu Saito

    Handbook on Lewis Acid, VCH & Wiley     page: 1-67   2000

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  88. 実用的な金属試薬、アルミニウム Invited

    斎藤 進

    ファルマシア   Vol. 36 ( 7 ) page: 610-611   2000

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  89. Asymmetric coupling of phenols with arylleads Reviewed

    S Saito, T Kano, H Muto, M Nakadai, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 121 ( 38 ) page: 8943 - 8944   1999.9

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  90. Directed aldol condensation Reviewed

    S Saito, H Yamamoto

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 5 ( 7 ) page: 1959 - 1962   1999.7

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    The present article covers the progress in directed aldol condensation, which can be divided into three different classes. First, the mixed aldol condensation that uses general acids or bases under protic conditions. Second, stepwise enolization-aldolization sequence that utilizes various metal enolates under aprotic conditions. Third, a novel mixed aldol condensation that makes use of a bulky Lewis acid and a lithium amide under aprotic conditions. The scope and limitation of each of three aldol strategies is discussed.

    Web of Science

  91. Mixed crossed aldol condensation between conjugated esters and aldehydes using aluminum tris(2,6-diphenylphenoxide) Reviewed

    Susumu Saito, Masahito Shiozawa, Hisashi Yamamoto

    Angewandte Chemie - International Edition   Vol. 38 ( 12 ) page: 1769 - 1771   1999.6

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    The combined use of aluminum tris(2,6-diphenylphenoxide) (ATPH) and lithium 2,2,6,6-tetramethylpiperidide (LTMP) has proven to be effective for the mixed crossed aldol condensation between conjugated esters and various aldehydes. An example is shown in Equation (1).

    DOI: 10.1002/(SICI)1521-3773(19990614)38:12<1769::AID-ANIE1769>3.0.CO;2-0

    Scopus

  92. Novel three component coupling of ketone, cyclic ether and epoxide using aluminum tris(2,6-diphenylphenoxide) (ATPH) Reviewed

    S Saito, S Yamazaki, M Shiozawa, H Yamamoto

    SYNLETT   ( 5 ) page: 581 - 583   1999.5

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    A ketone, cyclic ether, and epoxide are combined in one-pot using aluminum tris(2,6-diphenylphenoxide) (ATPH) and LDA, the latter agent being applied as the trigger for the reaction.

    Web of Science

  93. Designer Lewis acid catalysts for selective organic synthesis Reviewed

    H Yamamoto, S Saito

    PURE AND APPLIED CHEMISTRY   Vol. 71 ( 2 ) page: 239 - 245   1999.2

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:WALTER DE GRUYTER GMBH  

    The present paper covers the progress in stereo-, regio-, and chemoselective carbon-carbon bond-forming reactions promoted by structurally well-designed aluminum aryloxides. Compared with conventional Lewis acids, these aluminum reagents strongly coordinate with various oxygen-containing substrates, and the coordination aptitude is strongly affected by the steric environment of the metal ligands. In principle, the carbonyl groups of the bound substrates are electronically activated but sterically deactivated depending on the aluminum reagent and the type of the reaction employed. This review specifically highlights the selective organic reactions using ATPH.

    Web of Science

  94. Aluminum trisphenoxide polymer as a Lewis acidic, solid catalyst Reviewed

    S Saito, M Murase, H Yamamoto

    SYNLETT   ( 1 ) page: 57 - 58   1999.1

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    A newly introduced, solid polymer of an aluminum trisphenoxide has been demonstrated an efficient catalyst for promoting the Diels-Alder reaction of alpha,beta-enals.

    Web of Science

  95. Conjugate addition of lithium enolates to aromatic carbonyl compounds complexed with aluminum tris(2,6-diphenylphenoxide) (ATPH) Reviewed

    S Saito, T Sone, K Shimada, H Yamamoto

    SYNLETT   ( 1 ) page: 81 - 83   1999.1

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    Various lithium enolates of esters undergo effective 1,6-addition to aromatic carbonyl compounds in the presence of aluminum tris(2,6-diphenylphenoxide)(ATPH).

    Web of Science

  96. Designer Lewis acids for selective organic synthesis Reviewed

    H Yamamoto, A Yanagisawa, K Ishihara, S Saito

    PURE AND APPLIED CHEMISTRY   Vol. 70 ( 8 ) page: 1507 - 1512   1998.8

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    A variety of Lewis acid reagents were utilized for Diels-Alder, aldol, and ene reactions with high enantioselectivities. The origin of the selectivity of these reactions is discussed.

    Web of Science

  97. Conceptually new directed aldol condensation using aluminum tris(2,6-diphenylphenoxide) Reviewed

    S Saito, M Shiozawa, M Ito, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 120 ( 4 ) page: 813 - 814   1998.2

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  98. Diastereoselective aldol reaction with an acetate enolate: 2,6-bis(2-isopropylphenyl)-3,5-dimethylphenol as an extremely effective chiral auxiliary Reviewed

    S Saito, K Hatanaka, T Kano, H Yamamoto

    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   Vol. 37 ( 24 ) page: 3378 - 3381   1998

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  99. Designer Lewis acid catalysts - bulky aluminium reagents for selective organic synthesis Reviewed

    S Saito, H Yamamoto

    CHEMICAL COMMUNICATIONS   ( 17 ) page: 1585 - 1592   1997.9

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:ROYAL SOC CHEMISTRY  

    Sterically hindered aluminium aryloxides have been developed as designer Lewis acid catalysts for stereo-, regio- and chemo-selective carbon-carbon bond-forming reactions. Compared with classical Lewis acids, these aluminium reagents coordinate strongly with various oxygen-containing substrates, and this coordination is affected by the steric environment of their ligands, The carbonyl groups of the bound substrates are either electronically activated or sterically deactivated depending on the aluminium reagent used and the type of reaction, Designer chiral catalysts based on the structure of these bulky aluminium reagents have also been examined.

    Web of Science

  100. 2,6-bis(2-alkylphenyl)-3,5-dimethylphenol as a new chiral phenol with C-2-symmetry. Application to the asymmetric alkylation of aldehydes Reviewed

    S Saito, T Kano, K Hatanaka, H Yamamoto

    JOURNAL OF ORGANIC CHEMISTRY   Vol. 62 ( 16 ) page: 5651 - 5656   1997.8

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  101. A new synthetic route to allylsilanes: The reaction of silyllithium reagents with aromatic carbonyl compounds and aluminium tris(2,6-diphenylphenoxide) (ATPH) Reviewed

    S Saito, K Shimada, H Yamamoto, EM deMarigorta, Fleming, I

    CHEMICAL COMMUNICATIONS   ( 14 ) page: 1299 - 1300   1997.7

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    Conjugate 1,6-addition of silyllithium reagents to aromatic carbonyl substrates in the presence of the carbonyl protector aluminium tris(2,6-diphenylphenoxide) (ATPH) gives allylsilanes.

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  102. Regioselective Robinson annulation realized by the combined use of lithium enolates and aluminum tris(2,6-diphenylphenoxide) (ATPH) Reviewed

    S Saito, Shimada, I, Y Takamori, M Tanaka, K Maruoka, H Yamamoto

    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN   Vol. 70 ( 7 ) page: 1671 - 1681   1997.7

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    Michael addition of lithium enolates derived from ketones to a variety of alpha, beta-unsaturated ketones was realized in the presence of aluminum tris(2,6-diphenylphenoxide) (ATPH). In this reaction, ATPH can be used as a carbonyl protector of alpha, beta-unsaturated carbonyl substrates upon complexation, which facilitates the regioselective 1,4-addition of lithium enolates to Michael accepters. Similarly, dianions of beta-dicarbonyl compounds undergo Michael addition smoothly using ATPH as an effective promoter of the reaction. Subsequent regioselective, intramolecular aldol condensation was also demonstrated, leading to bicyclic carbon ring systems. Such systems are difficult to obtain by the Robinson annulation usually performed in protic media.

    Web of Science

  103. A new annulation based on a one-pot double Michael addition using aluminum tris(2,6-diphenylphenoxide) (ATPH) Reviewed

    S Saito, M Shiozawa, Y Takamori, H Yamamoto

    SYNLETT   ( 4 ) page: 359 - +   1997.4

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    An annulation system based on sequential inter- and intramolecular Michael addition was realized by the combined use of ketone enolates and aluminum tris(2,6-diphenylphenoxide)(ATPH).

    Web of Science

  104. Selective alkylation of ketones with a bulky aluminum reagent - The THF-TBSOTf system Reviewed

    S Saito, M Ito, K Maruoka, H Yamamoto

    SYNLETT   ( 4 ) page: 357 - +   1997.4

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    Various ketones can be alkylated with tetrahydrofuran (THF) to provide alpha-siloxybutylated ketones in the presence of a bulky aluminum reagent, lithium diisopropylamide (LDA), and t-butyldimethylsilyl triflate (TBSOTf).

    Web of Science

  105. Highly regioselective alkylation at the more-hindered alpha-site of unsymmetrical ketones by the combined use of aluminum tris(2,6-diphenylphenoxide) and lithium diisopropylamide Reviewed

    S Saito, M Ito, H Yamamoto

    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   Vol. 119 ( 3 ) page: 611 - 612   1997.1

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  106. Aluminum tris(4-bromo-2,6-diphenylphenoxide)(ATPH-Br): An effective catalyst for claisen rearrangement Reviewed

    S Saito, K Shimada, H Yamamoto

    SYNLETT   ( 8 ) page: 720 - +   1996.8

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    A new Lewis acidic receptor, aluminum tris(4-bromo-2,6-diphenylphenoxide)(ATPH-Br), is a powerful promoter of the Claisen rearrangement of various allyl vinyl ethers and is effective for controlling the stereochemistry of the resulting rearrangement products.

    Web of Science

  107. Efficient conjugate reduction of alpha,beta-unsaturated carbonyl compounds by complexation with aluminum tris(2,6-diphenylphenoxide) Reviewed

    S Saito, H Yamamoto

    JOURNAL OF ORGANIC CHEMISTRY   Vol. 61 ( 9 ) page: 2928 - 2929   1996.5

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  108. Retro-Synthetic Analysis

      Vol. 51   page: 34-36   1996

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  109. Molecular Design of aChiral Lewis Acid for Claisen Rearrangement Reviewed

    Keiji Maruoka, Susumu Saito, Hisashi Yamammoto

    Journal of AmericanChemical Society   Vol. 117   page: 1165   1995

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  110. Selective Organic Synthesis Using Novel Lewis Acidic Receptor

      Vol. 50   page: 58-59   1995

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  111. AsymmetricDiels-Alder Reaction of UnsymmetricalMaleates. A Chemical Access to Chiral, Unsymmetricalcis-Cyclohexene-1,2-di-carboxylates Reviewed

    Keiji Maruoka, Matsujiro Akakura, Susumu Saito, Takashi Ooi, Hisashi Yamammoto

    Journal of AmericanChemical Society   Vol. 116   page: 6153   1994

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  112. Virtually CompleteBlocking of α, β-Unsaturated AlbehydeCarbonyls by Complexation with AluminumTris(2,6-diphenylphenoxide) Reviewed

    Keiji Maruoka, Hiroshi Imoto, Susumu Saito, *Hisashi Yamammoto

    Journal of AmericanChemical Society   Vol. 116   page: 4131   1994

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  113. AluminumTris(2,6-diphenylphenoxide) as an Extremely Selective Activator of Less Hindered AldehydeCarbonyl Reviewed

    Keiji Maruoka, Susumu Saito, Hisashi Yamammoto

    Synlett     page: 439   1994

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  114. Regioncontrolled]2+2[ Cycloaddition of UnsymmetricalFumarates Based on the Discrimination of TwoDifferent Ester Carbonyl with MAD Reviewed

    Keiji Maruoka, Susumu Saito, Hisashi Yamammoto

    Synlett     page: 197   1993

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  115. Chemoselective Functionalization of More Hindered Aldehyde Carbonyl with Methyl-aluminumBis(2,6-diphenylphenoxide)/Alkyllithium System Reviewed

    Keiji Maruoka, Susumu Saito, Arnel B. Concepcion, Hisashi Yamammoto

    Journal of AmericanChemical Society   Vol. 115   page: 1183   1993

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  116. A New Strategy forObtaining High Level of Diastereoselectivityin the Asymmetric Diels-Alder Reaction of Chiral Dienophiles Reviewed

    Keiji Maruoka, Kei Shiohara, Masataka Oishi, Susumu Saito, Hisashi Yamammoto

    Synlett     page: 4321   1993

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  117. Discrimination of TwoDifferent Ester Carbonyl with MAD : Application to the Region and StereocontrolledDiels-Alder Reaction of UnsymmetricalFumarates Reviewed

    Keiji Maruoka, Susumu Saito, Hisashi Yamammoto

    Journal of AmericanChemical Society   Vol. 114   page: 1089   1992

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  118. Selective Reduction ofMethylenecyclalkane Oxides withDiisobutylaluminum2,6-di-tert-butyl-4-substituted-phenoxide Reviewed

    Keiji Maruoka, Susumu Saito, Takashi Ooi, Hisashi Yamammoto

    Synlett     page: 255   1991

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  119. A NEW StereoselectiveApproach to Oxygenated Carbocycles : Asymmetric Synthesis of the CyclohexylFragment of FK-506 Reviewed

    Keiji Maruoka, Susumu Saito, Takashi Ooi, Hisashi Yamammoto

    Synlett     page: 579   1991

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

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Books 41

  1. 十字路:Krebs(クレブス)回路

    吉岡頌太, 斎藤進( Role: Joint author)

    有機合成化学協会  2020.9 

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    Language:Japanese

  2. PNNP四座配位子をもつ精密金属錯体触媒を用いる再生可能炭素資源の還元法の開発

    吉岡頌太,鄭知恩,斎藤進( Role: Joint author)

    有機合成化学協会  2020.9 

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    Total pages:11   Language:Japanese

  3. 十字路:光誘起電子移動

    鄭知恩,斎藤進( Role: Joint author)

    有機合成化学協会  2020.9 

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    Total pages:1   Responsible for pages:1   Language:Japanese

  4. CSJ current Review, 高機能性金属錯体によるカルボン酸の水素化 Reviewed

    吉岡頌太,斎藤進( Role: Joint author)

    日本化学会  2020.4 

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    Total pages:11   Language:Japanese Book type:Scholarly book

  5. ニュースレター9号, 光エネルギーを化学エネルギーとして蓄える精密有機合成を目指して:水素マネージメント

    斎藤進( Role: Sole author)

    複合系光機能研究会  2019.6 

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    Total pages:2   Language:Japanese Book type:Scholarly book

  6. 理philosphia, 社会の役に立つとは Reviewed

    斎藤進( Role: Sole author)

    名古屋大学理学部  2017.4 

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    Total pages:1   Language:Japanese Book type:General book, introductory book for general audience

  7. 名大トピックス「知の先端」・持続可能社会に貢献できる触媒と化学を探す旅

    斎藤進( Role: Sole author)

    名古屋大学  2016.11 

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    Responsible for pages:10–11   Language:Japanese

  8. 化学工業<特集>戦略的触媒開発と応用・カルボン酸の水素化触媒の原型「ジホスフィン配位ルテニウムカルボキシラート」の発見と応用

    鳴戸真之, 斎藤進( Role: Joint author)

    化学工業社  2016.4 

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    Responsible for pages:317(1)–324(8)   Language:Japanese Book type:Scholarly book

  9. 触媒年鑑「触媒技術の動向と展望」・分子触媒表面を用いる不活性カルボン酸類の触媒的水素化の新展開

    斎藤進( Role: Sole author)

    触媒学会  2015 

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    Language:Japanese

  10. 月刊ケミカルエンジニアリング・光触媒を用いるバイオマス由来資源からの持続的プロピレン製造

    斎藤進( Role: Sole author)

    化学工業社  2014.7 

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    Language:Japanese

  11. バイオリファイナリーに挑む分子触媒たち

    斎藤進( Role: Sole author)

    化学同人  2013.11 

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    Language:Japanese

  12. アルコールとその誘導物質の電子的両性を利用した二酸化炭素の資源化法の開発

    中寛史,斎藤進( Role: Joint author)

    NTS出版  2013.4 

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    Language:Japanese

  13. Science of Synthesis, AlX, Knowledge Update

    H. Naka, S. Saito( Role: Joint author)

    Thieme  2011 

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    Language:English

  14. Science of Synthesis, AlH, Knowledge Update

    H. Naka, S. Saito( Role: Joint author)

    Thieme  2011 

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    Language:English

  15. 「使える!有機合成反応241実践ガイド」ニトリルの水和反応

    斎藤 進( Role: Sole author)

    化学同人  2010.4 

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    Language:Japanese

  16. 「使える!有機合成反応241実践ガイド」ニトリルの直截的アルドール型反応

    斎藤 進( Role: Sole author)

    化学同人  2010.4 

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    Language:Japanese

  17. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Me3Al – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2007 

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    Language:English

  18. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Et3Al – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2007 

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    Language:English

  19. *Comprehensive Organometallic Chemistry III; Aluminum

    Susumu Saito( Role: Sole author)

    Elsevier  2006 

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    Language:English

  20. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Methylaluminum Bis(2,6-di-t-butyl-4-bromophenoxide) – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2006 

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    Language:English

  21. Reagents for Organic Synthesis (e-EROS), Methylaluminum Bis(2,6-di-phenylphenoxide) – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2006 

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    Language:English

  22. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Methylaluminum Bis(2,6-di-t-butyl-4-methylphenoxide) – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2006 

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    Language:English

  23. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Methylaluminum Bis(2,6-di-t-butylphenoxide) – Update -’

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2006 

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    Language:English

  24. Encyclopedia of Reagents for Organic Synthesis (e-EROS), Methylaluminum Bis(2,4,6-tri-t-butylphenoxide) – Update -

    Susumu Saito( Role: Sole author)

    John Wiley & Sons  2006 

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    Language:English

  25. Science of Synthesis, Houben-Weyl Methods of Molecular Transformation; Al(0)

    ( Role: Sole author)

    2004 

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    Language:English

  26. Science of Synthesis, Houben-Weyl Methods of Molecular Transformation; Al-X

    Susumu Saito( Role: Sole author)

    Thieme  2004 

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    Language:English

  27. Science of Synthesis, Houben-Weyl Methods of Molecular Transformation; Al-H

    Susumu Saito( Role: Sole author)

    Thieme  2004 

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    Language:English

  28. Main Group Metals In Organic Synthesis; Lead (Pb)

    Taichi Kano, Susumu Saito( Role: Joint author)

    VCH & Wiley  2003 

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    Language:English

  29. Main Group Metals In Organic Synthesis; Aluminum (Al)

    ( Role: Sole author)

    2003 

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    Language:English

  30. Handbook on Lewis Acid; Li(I), Na(I) and K(I) Lewis Acids

    Susumu Saito( Role: Sole author)

    VCH & Wiley  2000 

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    Language:English

  31. Carbonyl Recognition, Modern Carbonyl Chemistry

    Susumu Saito, Hisashi Yamamoto( Role: Joint author)

    VCH & Wiley  2000 

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    Language:English

  32. 有機化学基礎の基礎; 逆合成

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  33. 有機化学基礎の基礎; シントン

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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  34. 有機化学基礎の基礎; 保護基

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  35. 有機化学基礎の基礎; エノラート、ケト-エノール互変異性

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  36. 有機化学基礎の基礎; 不斉誘導、触媒的不斉誘導

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  37. 有機化学基礎の基礎; 光学分割、速度論的分割

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  38. 有機化学基礎の基礎; 光学純度

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  39. 有機化学基礎の基礎; ラセミ体、メソ体

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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    Language:Japanese

  40. 有機化学基礎の基礎; Cahn-Ingold-Prelog法

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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  41. 有機化学基礎の基礎; キラル、アキラル

    斎藤 進、山本 尚( Role: Joint author)

    化学同人  1997 

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MISC 12

  1. N-Alkylation of functionalized amines with alcohols using a copper-gold mixed photocatalytic system Reviewed

    Lyu-Ming Wang, Yuna Morioka, Kellie Jenkinson, Andrew E. H. Wheatley, Susumu Saito, Hiroshi Naka

    Scientific Reports   Vol. 8 ( 1 )   2018.12

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:Nature Publishing Group  

    Direct functionalization of amino groups in complex organic molecules is one of the most important key technologies in modern organic synthesis, especially in the synthesis of bio-Active chemicals and pharmaceuticals. Whereas numerous chemical reactions of amines have been developed to date, a selective, practical method for functionalizing complex amines is still highly demanded. Here we report the first late-stage N-Alkylation of pharmaceutically relevant amines with alcohols at ambient temperature. This reaction was achieved by devising a mixed heterogeneous photocatalyst in situ prepared from Cu/TiO2 and Au/TiO2. The mixed photocatalytic system enabled the rapid N-Alkylation of pharmaceutically relevant molecules, the selective mono-and di-Alkylation of primary amines, and the non-symmetrical dialkylation of primary amines to hetero-substituted tertiary amines.

    DOI: 10.1038/s41598-018-25293-z

    Scopus

  2. Diboron-Catalyzed Dehydrative Amidation of Aromatic Carboxylic Acids with Amines Reviewed

    Sawant Dinesh N, Bagal Dattatraya B, Ogawa Saeko, Selvam Kaliyamoorthy, Saito Susumu

    ORGANIC LETTERS   Vol. 20 ( 15 ) page: 4397-4400   2018.8

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)  

    DOI: 10.1021/acs.orglett.8b01480

  3. Photocatalytic hydrogenolysis of allylic alcohols for rapid access to platform chemicals and fine chemicals Invited Reviewed

    Yuki Takada, Joaquim Caner, Hiroshi Naka, Susumu Saito

    Pure and Applied Chemistry   Vol. 90 ( 1 ) page: 167 - 174   2018.1

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:Walter de Gruyter GmbH  

    A brief account of our recent work on the chemo-, regio- and stereoselective photocatalytic hydrogenolysis of allylic alcohols to alkenes promoted by palladium-loaded titanium oxide (Pd/TiO2) photocatalysts is presented. Since methanol is employed as the reducing agent, the method does not involve stoichiometric generation of salt waste. The photocatalytic hydrogenolysis proceeds at room temperature, and is compatible with the presence of functional groups such as C=C double bonds and hydroxyl groups at non-allylic positions. The regioselectivity is predictable: the hydrogen atom is predominantly incorporated into the sterically less hindered carbon atom of the allylic moiety. This protocol should provide straightforward green access to a range of platform chemicals (exemplified by the two-step synthesis of propylene from glycerol) and fine chemicals [e.g. (S)-(+)-lavandulol from (R)-(-)-carvone] without the need for protection/deprotection steps.

    DOI: 10.1515/pac-2017-0501

    Scopus

  4. Photocatalytic Transfer Hydrogenolysis of Allylic Alcohols on Pd/TiO2: A Shortcut to (S)-(+)-Lavandulol

    Yuki Takada, Joaquim Caner, Selvam Kaliyamoorthy, Hiroshi Naka, Susumu Saito

    CHEMISTRY-A EUROPEAN JOURNAL   Vol. 23 ( 71 ) page: 18025 - 18032   2017.12

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:WILEY-V C H VERLAG GMBH  

    We report herein a regio- and stereoselective photocatalytic hydrogenolysis of allylic alcohols to form unsaturated hydrocarbons employing a palladium(II)-loaded titanium oxide; the reaction proceeds at room temperature under light irradiation without stoichiometric generation of salt wastes. Olefin and saturated alcohol moieties tolerated the reaction conditions. Hydrogen atoms were selectively incorporated into less sterically congested carbons of the allylic functionalities. This protocol allowed a short-step synthesis of (S)-(+)-lavandulol from (R)-(-)-carvone by avoiding otherwise necessary protection/deprotection steps.

    DOI: 10.1002/chem.201704099

    Web of Science

  5. Catalytic transformation of functionalized carboxylic acids using multifunctional rhenium complexes

    Masayuki Naruto, Santosh Agrawal, Katsuaki Toda, Susumu Saito

    SCIENTIFIC REPORTS   Vol. 7   2017.6

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:NATURE PUBLISHING GROUP  

    Carboxylic acids (CAs) are one of the most ubiquitous and important chemical feedstocks available from biorenewable resources, CO2, and the petrochemical industry. Unfortunately, chemoselective catalytic transformations of CHnCO2H (n = 1-3) groups into other functionalities remain a significant challenge. Herein, we report rhenium(V) complexes as extremely effective precatalysts for this purpose. Compared to previously reported heterogeneous and homogeneous catalysts derived from high- or low-valent metals, the present method involves a alpha-C-H bond functionalization, a hydrogenation, and a hydrogenolysis, which affords functionalized alcohols with a wide substrate scope and high chemoselectivity under relatively mild reaction conditions. The results represent an important step toward a paradigm shift from 'low-valent' to 'high-valent' metal complexes by exploring a new portfolio of selective functional group transformations of highly oxygenated organic substrates, as well as toward the exploitation of CAs as a valuable biorenewable feedstock.

    DOI: 10.1038/s41598-017-03436-y

    Web of Science

  6. Multifaceted catalytic hydrogenation of amides via diverse activation of a sterically confined bipyridine-ruthenium framework

    Takashi Miura, Masayuki Naruto, Katsuaki Toda, Taiki Shimomura, Susumu Saito

    SCIENTIFIC REPORTS   Vol. 7   2017.5

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    Amides are ubiquitous and abundant in nature and our society, but are very stable and reluctant to salt-free, catalytic chemical transformations. Through the activation of a "sterically confined bipyridineruthenium (Ru) framework (molecularly well-designed site to confine adsorbed H-2 in)" of a precatalyst, catalytic hydrogenation of formamides through polyamide is achieved under a wide range of reaction conditions. Both C=O bond and C-N bond cleavage of a lactam became also possible using a single precatalyst. That is, catalyst diversity is induced by activation and stepwise multiple hydrogenation of a single precatalyst when the conditions are varied. The versatile catalysts have different structures and different resting states for multifaceted amide hydrogenation, but the common structure produced upon reaction with H-2, which catalyzes hydrogenation, seems to be "H-Ru-N-H."

    DOI: 10.1038/s41598-017-01645-z

    Web of Science

  7. Dehydrogenation of Primary Aliphatic Alcohols by Au/TiO2 Photocatalysts Reviewed

    Masaki Shibata, Ryoko Nagata, Susumu Saito, Hiroshi Naka

    CHEMISTRY LETTERS   Vol. 46 ( 4 ) page: 580 - 582   2017.4

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:CHEMICAL SOC JAPAN  

    Dehydrogenation reaction of primary aliphatic alcohols to aldehydes and molecular hydrogen was achieved under UV-vis light irradiation in the presence of gold-loaded titanium dioxide (Au/TiO2) photocatalysts.

    DOI: 10.1246/cl.161195

    Web of Science

  8. Investigation of the Corey Bromolactamization with N-Functionalized Allylamines Reviewed

    Adrian Schulte, Simon Janich, Ernst-Ulrich Wuerthwein, Susumu Saito, Bernhard Wuensch

    JOURNAL OF HETEROCYCLIC CHEMISTRY   Vol. 53 ( 6 ) page: 1827 - 1837   2016.11

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    N-Allylamines were employed for the diastereoselective synthesis of 8-bromo-substituted, cis-configured perhydroquinoxalines and beta-bromoalcohols. The yield and constitution of the products depend considerably on the functionalization of the allylic N-atom. Herein the reaction of glycine-derived cyclohex-2-enamines 5 under bromolactamization conditions (LiOtBu, NBS) is reported. Methyl carbamate 5a led diastereoselectively to the cis-configured perhydroquinoxaline 6a, whereas the amides 5b and 5c provided cis, trans-configured -bromoalcohols 7b and 7c. Based on high level theoretical calculations (DFT) factors controlling the cyclization of lithiated intermediates and the relative energies of possible products are discussed.

    DOI: 10.1002/jhet.2493

    Web of Science

  9. Versatile Ruthenium Complex RuPCY for Directed Catalytic Hydrogen Management in Organic Synthesis Invited Reviewed

    Yuki Takada, Megumi Iida, Kazuki Iida, Takashi Miura, Susumu Saito

    J. Syn. Org. Chem. Jpn.   Vol. 74 ( 11 ) page: 1078–1088   2016.11

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  10. Versatile Ruthenium Complex "RuPCY" for Directed Catalytic Hydrogen Management in Organic Synthesis Reviewed

    Takada Yuki, Iida Megumi, Iida Kazuki, Miura Takashi, Saito Susumu

    JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN   Vol. 74 ( 11 ) page: 1078-1089   2016.11

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  11. Synthesis of morphan derivatives with additional substituents in 8-position Reviewed

    Janine Stefaowitz, Dirk Schepmann, Constantin Daniliuc, Susumu Saito, Bernhard Wuensch

    ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES   Vol. 71 ( 10 ) page: 1057 - 1069   2016.10

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:WALTER DE GRUYTER GMBH  

    The morphan system (2-azabicyclo[3.3.1]no-nane) as a substructure of morphine is of major interest in medicinal chemistry. Herein, the synthesis of morphan derivatives with additional substituents at the propano bridge is reported. In order to avoid the isolation of the smelly and volatile nitrile 6 and the very polar primary amine 9, an efficient one-pot, three-step sequential transformation of the mesylate 5 into amides 10 was developed. The key step of the synthesis was the stereoselective intramolecular opening of the epoxides 11a-d leading to the exo-configured 8-hydroxymorphans 12a-d. The configuration of the exo-configured hydroxymorphan 12d bearing the kappa- and sigma-pharmacophoric 3,4-dichlorophenylacetyl moiety was inverted by oxidation and stereoselective reduction. An X-ray crystal structure analysis of the benzamide 12c confirmed the relative configuration of the hydroxymorphans 12a-d and 14d.

    DOI: 10.1515/znb-2016-0129

    Web of Science

  12. Stereoselective Synthesis of cis,cis-Configured Perhydroquinoxaline-5-Carbonitrile from Cyclohex-2-en-1-ol Reviewed

    Adrian Schulte, Susumu Saito, Bernhard Wuensch

    JOURNAL OF HETEROCYCLIC CHEMISTRY   Vol. 53 ( 2 ) page: 533 - 536   2016.3

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    Language:English   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:WILEY-BLACKWELL  

    cis,cis-Configured perhydroquinoxaline-5-carbonitrile 10 was synthesized stereoselectively by ditosylation of trans,cis-2,3-dihydroxycyclohexane-1-carbonitrile 4 and subsequent reaction with ethylenediamine. The diol precursor 4 was stereoselectively obtained by regioselective opening of the epoxide 3 with KCN in water avoiding hazardous Et2AlCN.

    DOI: 10.1002/jhet.2322

    Web of Science

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Presentations 127

  1. 精密錯体触媒を用いる安定カルボン酸誘導体の水素化法の開拓と応用 Invited

    斎藤進

    第115回有機合成シンポジウム企業冠賞受賞講演  2019.6.4 

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    Event date: 2019.6

    Venue:東北大学青葉山コモンズ,仙台  

  2. Catalytic hydrogen management of renewable feedstock:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    LIKAT seminar, Leibniz-Institut für Katalyse (LIKAT)  2018.2.4 

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    Event date: 2018.2

    Venue:Rostock University, Rostock, Germany  

  3. Catalytic hydrogen management:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    International Symposium on Catalysis for Sustainable Chemical Synthesis 

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    Event date: 2017.9

    Venue:Freiburg University, Freiburg i. Brsg  

  4. Catalytic hydrogenation of carboxylic acids using low- and high-valent transition metal complexes Invited International conference

    Susumu Saito

    2017 Organometallic Chemistry, Gordon Research Conference (GRC) 

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    Event date: 2017.7

    Venue:Salve Regina University, Newport, RI, USA  

  5. エネルギー多様性に応答する遷移金属錯体:CO2の還元的資源化 Invited

    斎藤進

    東海化学工業会セミナー「CO2 削減に関する研究開発の最前線」  2021.11.26  東海化学工業会

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    Event date: 2021.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋   Country:Japan  

  6. 水やCO2から有機合成する? Invited

    斎藤進

    ITbM/GTRコンソーシアム2021年第7回ワークショップGTR Seeds Seminar  2021.6.9  GTR

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    Event date: 2021.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋   Country:Japan  

  7. 分子触媒を用いるカルボン酸の水素化 Invited International conference

    斎藤進

    第127回触媒討論会特別シンポジウム(触媒学会)  2021.3.17 

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    Event date: 2021.3

    Language:English   Presentation type:Oral presentation (invited, special)  

  8. 水素を使ったカルボン酸還元技術 Invited

    斎藤進

    産学連携クリーンテック,名古屋商工会議所(名商ecoクラブ)  2021.2.25 

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    Event date: 2021.2

    Venue:名古屋商工会議所  

  9. 水素マネージメントと再生可能な炭素資源開拓 Invited

    斎藤進

    GTRシリーズ講義第5回2020  2020.7.22 

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    Event date: 2020.7

    Venue:名古屋大学  

  10. TiO2-based photocatalysis for selective organic synthesis and fine chemicals Invited International conference

    Susumu Saito

    3rd International Solar Fuels Conference/International Conference on Artificial Photosynthesis-2019 

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    Event date: 2019.11

    Venue:Hiroshima Convention Hall, Hiroshima, Japan  

  11. Catalytic hydrogen management: Dehydrogenative photocatalysis follows hydrogenation of carboxylic acid derivatives Invited International conference

    Susumu Saito

    School of Chemical Engineering, Nanjing Tech University, NJTech Chemistry Seminar  2019.10.26 

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    Event date: 2019.10

    Venue:Nanjing University of Technology, Nanjing, China  

  12. Catalytic hydrogen management: Dehydrogenative photocatalysis follows hydrogenation of carboxylic acid derivatives Invited International conference

    Susumu Saito

    School of Chemical Engineering, Soochow University, SU Materials Chemistry Seminar  2019.10.25 

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    Event date: 2019.10

    Venue:Soochow University, Suzhou, China  

  13. Hydrogenation catalysis followed by semiconductor photocatalysis for fine chemicals synthesis Invited International conference

    Susumu Saito

    Zhejiang University Pharmaceutical Seminar  2019.10.23 

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    Event date: 2019.10

    Venue:Zejiang University, Hanzhou, China  

  14. Catalytic hydrogen management: Dehydrogenative photocatalysis follows hydrogenation of carboxylic acid derivatives Invited International conference

    Susumu Saito

    School of Chemical Engineering, Nanjing University of Science and Technology (NJUST) Chemical Enginnering Visiting Professor Seminar  2019.10.22 

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    Event date: 2019.10

    Venue:Nanjing University of Science and Technology, Nanjing, China  

  15. 遷移金属触媒を用いる再生可能資源の精密化学変換への挑戦:「暗所」水素化から「光所」脱水素化へ…その後は? Invited

    斎藤進

    第50回有機金属若手の会夏の学校 

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    Event date: 2019.8

    Venue:定山渓万世閣 ホテルミリオーネ, 札幌,北海道  

  16. 分子触媒と固体触媒のクロスオーバー領域の精密化に基づく二酸化炭素の資源化法を目指して Invited

    斎藤進

    JACI / JST 交流セミナー JST「先導的物質変換領域」(ACT-C)研究者との集い  2019.8.4 

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    Event date: 2019.8

    Venue:新化学技術推進協会,東京  

  17. 再生可能資源とCO2からのモノづくり Invited

    斎藤進

    夢ナビTalk 2019(主催:フロムページ)  2019.7.20 

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    Event date: 2019.7

    Venue:ポートメッセなごや,名古屋  

  18. 水素と光を操り有機物質生産を変える Invited

    斎藤進

    夢ナビ講義ライブ 2019(主催:フロムページ)  2019.7.20 

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    Event date: 2019.7

    Venue:ポートメッセなごや,名古屋  

  19. Catalytic Hydrogen Management for Sustainable Future Invited International conference

    Susumu Saito

    NU-UoE JD and JSPS CtC Joint Workshop “New Horizons in Chemistry and Materials Science”,  2019.7.1 

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    Event date: 2019.7

    Venue:Nagoya University  

  20. Looking for the bridge between photo-organic synthesis and surface catalysis science, Invited International conference

    Susumu Saito

    The 1st Workshop of Reaction Infography (R-ing) Unit of WPI-next  2019.6.11 

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    Event date: 2019.6

    Venue:Nagoya University  

  21. 光と熱を用いる触媒的水素・電子マネージメント:再生可能資源の有効利用法へのアプローチ Invited

    斎藤進

    2019革新化学反応研究会  2019.6.8 

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    Event date: 2019.6

    Venue:休暇村支笏湖,北海道  

  22. Semiconductor Photocatalysis of Renewable Alcohol and Amine Feedstock: Hydrogen Management for Fine Chemical Synthesis, Invited International conference

    Susumu Saito

    International Conference on Photocatalysis and Photoenergy 2019 (ICOPP2019) 

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    Event date: 2019.5

    Venue:Orakai Songdo Park Hotel、Incheon, Korea  

  23. カルボン酸水素化触媒の高機能化と光学活性化合物合成への展開 Invited

    斎藤進

    長瀬科学技術振興財団 平成30年度成果発表会  2019.4.25 

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    Event date: 2019.4

    Venue:大阪科学技術センター8階大ホール,難波,大阪  

  24. 有機合成・物質生産を変えるか:触媒的水素マネージメント Invited

    斎藤進

    第2回名古屋大学理学部化学教室IDAB委員会  2019.2.22 

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    Event date: 2019.2

    Venue:名古屋  

  25. Catalytic hydrogen management for sustainable resources:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    WWU Chemistry Seminar  2019.1.18 

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    Event date: 2019.1

    Venue:Münster (University of Münster), Münster, Germany  

  26. Catalytic hydrogen management for sustainable resources:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    Institute of Technical and Macromolecular Chemistry Seminar  2019.1.17 

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    Event date: 2019.1

    Venue:RWTH Aahen University, Aachen, Germany  

  27. Catalytic hydrogen management for sustainable resources:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    OC Colloquium  2019.1.16 

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    Event date: 2019.1

    Venue:Justus–Liebig–Universität Gießen (University of Gießen), Gießen, Germany  

  28. Catalytic hydrogen management for sustainable resources:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    Kolloquium für Chemie und Chemische Biologie  2019.1.14 

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    Event date: 2019.1

    Venue:Fachbereich Chemie, Phillipps–Universität Marburg (University of Marburg), Marburg, Germany  

  29. Catalytic hydrogen management for renewable feedstock:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    International Conference on Advanced and Applied Petroleum, Petrochemicals, and Polymers in 2018 (ICAPPP 2018) 

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    Event date: 2018.12

    Venue:Chulalongkorn University, Bangkok, Thailand  

  30. Catalytic hydrogen management:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    National Institute of Advanced Industrial Science and Technology (AIST) Seminar  2018.3.23 

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    Event date: 2018.3

    Venue:Tukuba, Japan  

  31. Catalytic hydrogen management:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    Okinaka Institute of Science and Tchnology (OIST) Seminar  2018.3.19 

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    Event date: 2018.3

    Venue:OIST, Okinawa, Japan  

  32. Catalytic hydrogen management:hydrogenation under dark and dehydrogenation under light Invited International conference

    Susumu Saito

    JSPS 3nd Core-to-core Seminar  2018.2.3 

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    Event date: 2018.2

    Venue:University of Münster, Münster, Germany  

  33. 触媒的水素マネージメント:熱と光で水素を操る化学変換 Invited

    斎藤進

    非常勤講師特別講演会(群馬大学大学院理工学府学府セミナー)  2017.12.15 

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    Event date: 2017.12

    Venue:群馬大学,桐生,群馬  

  34. 遷移金属触媒を用いる再生可能資源の水素化と脱水素化 Invited

    斎藤進

    統合物質創製化学機構 第3回国内シンポジウム  2017.10.30 

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    Event date: 2017.10

    Venue:京都大学化学研究所,京都  

  35. 遷移金属錯体を用いるバイオマス関連カルボン酸の触媒的水素化

    斎藤進

    第100回触媒討論会 

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    Event date: 2017.9 - 2019.9

    Venue:愛媛大学,松山,愛媛  

  36. 触媒的水素マネージメント:水素を操る化学変換 Invited

    斎藤進

    先進触媒開発研究センター第1回シンポジウム 

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    Event date: 2017.3

    Language:Japanese   Presentation type:Oral presentation (keynote)  

    Venue:豊田工業大学8号棟第講義室,名古屋   Country:Japan  

  37. 化学分野の将来展望 持続可能社会への化学の貢献を目指して Invited

    斎藤進

    ACT-C第1回社会的貢献推進会議  2017.3.4 

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    Event date: 2017.3

    Venue:JST東京本部別館,市ヶ谷,東京  

  38. 触媒的水素マネージメント:再生可能資源に豊富な官能基の還元と脱水 Invited

    斎藤進

    三井化学(株)研究セミナー 

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    Event date: 2017.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  39. 精密水素移動場を用いるペプチド類の脱水的形成と変換 Invited International conference

    斎藤進

    真島新学術領域研究 第2回公開シンポジウム  2017.1.25 

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    Event date: 2017.1

    Language:Japanese   Presentation type:Oral presentation (general)  

  40. Metal carboxylylates as prototypical catalysts for self-induced hydrogenation of carboxylic acids Invited International conference

    Susumu Saito

    Catalysis & Fine Chemicals (C&FC) 

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    Event date: 2016.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Howard Civil Service International House, Taipei   Country:Taiwan, Province of China  

  41. 金属カルボキシラートを触媒構造の原型とするカルボン酸の自己誘導型カルボン酸の水素化 Invited

    鳴戸真之、Santosh Agrawal, 戸田勝章、吉岡頌太、斎藤進

    第63回有機金属化学討論会 

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    Event date: 2016.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  42. Catalytic hydrogen management: transformation of biomass-related inert compounds under light and dark Invited International conference

    Susumu Saito

    The 7th Annual Global Congress of Catalysis (GCC-2016) 

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    Event date: 2016.6 - 2016.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Seoul, Korea   Country:Korea, Republic of  

  43. Catalytic hydrogen management using molecular- and photo-catalysis: transformation of biomass-related inert compounds Invited International conference

    JSPS 2nd Core-to-core Seminar  2016.6.29 

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    Event date: 2016.6

    Language:English   Presentation type:Oral presentation (invited, special)  

  44. 精密水素移動場を用いる修飾アミノ酸類の触媒的高効率脱水変換 Invited

    斎藤進

    真島新学術領域研究 第1回全体会議 

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    Event date: 2016.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  45. 持続可能社会に化学でどう挑むか Invited

    斎藤進

    有機化学研究会:最先端の学術動向と未来技術 

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    Event date: 2016.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:湯の宿 木もれび,おごと温泉,滋賀   Country:Japan  

  46. Catalytic hydrogen management: salt-free transformation fo inert compounds to carbon feedstock Invited International conference

    Susumu Saito

    I2CNER International Workshop on Recent Progress in Bio-inspired Catalysis and Utilization of Earth-Abundant Resources 

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    Event date: 2016.2

    Language:English   Presentation type:Oral presentation (keynote)  

    Country:Japan  

  47. Hydrogen management for transformation of CO2- and biomass-derived feedstock using molecular surface International conference

    Susumu Saito

    Pacifichem 2015 

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    Event date: 2015.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:United States  

  48. Catalytic hydrogen management: salt-free transformation of inert compounds to carbon resources International conference

    Susumu Saito

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    Event date: 2015.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:United Kingdom  

  49. 水素マネージメントに基づく次世代触媒化学と有機合成戦略

    斎藤進

    2015年秋季有機合成講習会 

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    Event date: 2015.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  50. Catalytic hydrogen management: salt-free transformation of inert compounds to carbon feedstock International conference

    Campus Asia Symposium 

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    Event date: 2015.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  51. Hydrogen management: transformation of inert compounds to carbon resources for sustainable society International conference

    2nd IRTG meeting 2027 

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    Event date: 2015.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Germany  

  52. Catalytic molecular surface as a new interface between molecule and material for hydrogenation International conference

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    Event date: 2015.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Singapore  

  53. 化学で挑む21世紀の重要課題

    斎藤進

    サロン・ド・有本 

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    Event date: 2015.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  54. 分子表面の多彩な活性化に基づく不活性カルボン酸誘導体の水素化

    斎藤進

    第8回分子活性化公開シンポジウム 

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    Event date: 2015.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  55. Hydrogen Management Catalysis Using Thermal and Light Energy for Organic Synthesis International conference

    Susumu Saito

    The 18th (FINAL) Joint IRTG Symposium for Nagoya-Muenster University 

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    Event date: 2014.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  56. Hydrogen Management Catalysis for Transformation of CO2- and Biomass-derived Feedstock International conference

    Susumu Saito

    Vietnam and Malaysia International Chemical Congress (VMICC) 

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    Event date: 2014.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Viet Nam  

  57. Hydrogen Management for Chemcial Transformation of CO2- and Biomass-derived Feedstock International conference

    Susumu Saito

    18th Malaysian International Chemical Congress (18MICC) 

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    Event date: 2014.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Malaysia  

  58. 半導体光触媒を用いる酸化・還元の精密有機合成への展開

    Joaquim Caner, Zijun Liu, 工藤昭彦,中寛史,斎藤進

    光化学討論会2014 

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    Event date: 2014.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  59. Selective Hydrogenation of Inert Carbonyl Compounds Using Catalytic Molecular Surface Built on Transition Metals International conference

    Susumu Saito

    41st International Conference on Coordination Chemistry (ICCC-41) 

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    Event date: 2014.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Singapore  

  60. Hydrogenation of Carboxylic Acid Derivatives Using Catalytic Molecular Surface (CMS) International conference

    Susumu Saito

    International Symposium of Homogeneous Catalysis XIX (ISHCXIX) 

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    Event date: 2014.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Canada  

  61. Hydrogen Management for Sustainable Organic Synthesis: Control of Hydrogen Transfer Diversity in Catalysis Involving Alcohols International conference

    Susumu Saito

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    Event date: 2014.7

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Canada  

  62. 水素マネージメント」触媒を用いるバイオマス由来物質の合成的利用

    斎藤進

    第94日本化学会春季年会アドバンスト・テクノロジー・プログラム (ATP) セッション 

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    Event date: 2014.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  63. New Catalysis for Hydrogen Management International conference

    SJTU-NU inter-university research seminar for Ph.D. course students -Campus Asia- 

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    Event date: 2014.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  64. 新触媒で脱石油化学に挑む

    斎藤進

    名大Cafe,Science, and Me 

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    Event date: 2013.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  65. Hydrogen Management: Hydrogenation and Dehydrogenation for Organic Synthesis International conference

    Susumu Saito

    The 16th Joint IRTG Symposium for Nagoya-Muenster University 

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    Event date: 2013.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Germany  

  66. 水素マネージメントに基づく触媒開発は次世代物質生産の基盤になりうるか?基幹化学物質から医薬関連物質の合成まで

    斎藤進

    (株)三菱化学科学技術研究センター講演会 

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    Event date: 2013.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  67. Catalytic Hydrogenation of Unactivated Amides International conference

    Susumu Saito

    The 15th Asian Chemical Congress (ACC-15) 

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Singapore  

  68. Catalytic Hydrogenation of Unactivated Amides Going Milder and Practical International conference

    The International Symposium on Relations between Homogeneous and Heterogeneous Catalysis (ISHHC-16) 

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    Event date: 2013.8

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  69. 分子性の触媒表面を用いる不活性アミドの触媒的水素化

    斎藤進

    第5回分子活性化公開シンポジウム 

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    Event date: 2013.5

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  70. Catalytic Hydrogenation of Unactivated Amides International conference

    Susumu Saito

    The 2nd Campus Asia Symposium on Frontiers of Chemistry and Materials 

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    Event date: 2013.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  71. Catalytic Hydrogenation of Unactivated Amides International conference

    Susumu Saito

    1st KAUST Symposium on Functional Molecules and Materials (KSFMM) 

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    Event date: 2012.12

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Saudi Arabia  

  72. 脱石油化学に挑む:次世代触媒化学の創成を目指して

    斎藤 進

    平成24年度日本理化学協会東海ブロック研究会第18回研究発表大会 

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    Event date: 2012.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  73. Catalytic Hydrogenation of Unactivated Amides International conference

    Susumu Saito

    17th Malaysian Chemical Congress (17MCC) 

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    Event date: 2012.10

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Malaysia  

  74. Catalytic Transformation of Amides International conference

    Susumu Saito

    The 13th Joint IRTG Symposium for Nagoya/Münster University 

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    Event date: 2012.5

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  75. Hydrogenicsに基づく炭素資源利用 –不活性分子の活性化から医薬品の合成まで– International conference

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    Event date: 2012.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  76. Catalytic Alcoholysis of Amides International conference

    Susumu Saito

    The First Nagoya Symposium on Green Synthesis & Catalysis (NSGSC-1) 

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    Event date: 2012.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  77. Toward the Construction of an Interface between Homogeneous and Heterogeneous Catalysis International conference

    Susumu Saito, Takashi Miura, Shunsuke Oishi

    The CRC International Symposium on Green & Sustainable Catalysis: from Theoretical and Fundamental Aspects to Catalyst Design 

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    Event date: 2012.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  78. 均一系触媒と不均一系触媒のインターフェース構築を目指して:アミドの触媒的水素化

    斎藤 進

    新学術領域研究「分子活性化」第2回公開シンポジウム 

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    Event date: 2012.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  79. Hydrogenics: Principle and Applications, The 11th Tateshina Conference on Organic Chemistry International conference

    Susumu Saito

    Tateshina Forum 

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    Event date: 2011.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  80. 低反応性官能基の水素化と脱水素化を可能とする多機能性ルテニウム錯体触媒

    斎藤 進

    科学技術振興機構(JST)主催『大学連携新技術説明会』 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  81. ハイドロジェニクスに基づく炭素資源利用 –アルコールの形成と反応の新展開

    斎藤 進

    第2回統合物質科学シンポジウム 

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    Event date: 2011.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  82. Control of Diversity in Hydrogen Atom Transfer in Molecular Catalysis: Borrowing Hydrogen or Not International conference

    Susumu Saito

    The 5th Asian Network of Metal Chemistry in The 14th Asian Chemical Congress (ACC) 

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    Event date: 2011.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  83. Control of diversity in hydrogen transfer for drug synthesis: atom economical and rapid approach to Aricept® and Lipitor® International conference

    Susumu Saito, Megumi Suzuki, Kazuki Iida, Takashi Miura

    The 2nd International Symposium on Process Chemistry (ISPC2011) 

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    Event date: 2011.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  84. 新触媒活性種創製に基づくアミドの触媒的水素化 International conference

    斎藤 進

    茶谷新学術領域研究第1回全体会議 

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    Event date: 2011.5

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大阪大学中之島センター、大阪   Country:Japan  

  85. Acid-base cooperative catalysis for activation of alcohol as electrophile International conference

    Susumu Saito

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  86. Directed Activation of Alcohols for Organic Synthesis: Controlling Diversity in Hydrogen Atom Transfer in Molecular Catalysis through its Beyond International conference

    Susumu Saito

    Asian Core Program Lectureship Award Lecturer 

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  87. Directed Activation of Alcohols for Organic Synthesis: Controlling Diversity in Hydrogen Atom Transfer in Molecular Catalysis through its Beyond International conference

    Susumu Saito

    Asian Core Program Lectureship Award Lecturer 

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  88. Directed Activation of Alcohols for Organic Synthesis: Controlling Diversity in Hydrogen Atom Transfer in Molecular Catalysis through its Beyond International conference

    Susumu Saito

    Asian Core Program Lectureship Award Lecturer 

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  89. Directed Activation of Alcohols for Organic Synthesis: Controlling Diversity in Hydrogen Atom Transfer in Molecular Catalysis through its Beyond International conference

    Susumu Saito

    Asian Core Program Lectureship Award Lecturer 

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  90. New Aspects in the Synthesis of Dialkyl Carbonate from CO2 Based on Alcohol Activation International conference

    Susumu Saito

    Campus Asia Symposium 

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    Event date: 2011.3

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:China  

  91. Direct and Directed Activation of Alcohol for Organic Synthesis: Pursuing Hydrogen Bonds and Hydrogen Transfer in Molecular Catalysis through Its Beyond International conference

    Asian Core lectureship Award Lecture in National Taiwan University 

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    Event date: 2010.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  92. Direct and Directed Activation of Alcohol for Organic Synthesis: Pursuing Hydrogen Bonds and Hydrogen Transfer in Molecular Catalysis through Its Beyond International conference

    Asian Core lectureship Award Lecture in Academia Sinica, Taiwan 

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    Event date: 2010.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  93. Direct and Directed Activation of Alcohol for Organic Synthesis: Pursuing Hydrogen Bonds and Hydrogen Transfer in Molecular Catalysis through Its Beyond International conference

    Asian Core lectureship Award Lecture in National Tsing Hua University 

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    Event date: 2010.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  94. Activation of Alcohol as Electrophile for Organic Synthesis International conference

    9th Joint IRTG Symposium for Nagoya-Mu¨nster University 

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    Event date: 2010.12

    Language:English   Presentation type:Oral presentation (invited, special)  

  95. 化学資源の有用利用法を目指して-鍵を握るか:水素と二酸化炭素

    野依フォーラム第30回例会 

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    Event date: 2010.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  96. Selective Activation and Catalysis of Alcohols for C-C and C-N Bond Formations International conference

    The Inaugural (1st) International Conference on Molecular and Functional Catalysis (ICMFC-1) 

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    Event date: 2010.7

    Language:English   Presentation type:Oral presentation (invited, special)  

  97. Design of Chiral AminoOrganoBoron (AOB) Complexes for Molecular Recognition and Catalysis International conference

    The 1st Annual World Congress of Catalytic Asymmetric Synthesis-2010 (WCCAS-2010) 

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    Event date: 2010.5

    Language:English   Presentation type:Oral presentation (invited, special)  

  98. 水素移動多様性の制御に基づく新分子触媒反応の開発

    九州大学先導物質化学研究所 有機化学講演会 

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    Event date: 2010.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  99. アルコールの選択的活性化に基づく触媒的化学変換の新展開

    九州大学先導物質化学研究所 特別講演会 

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    Event date: 2010.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  100. Selective Activation and Reaction of Alcohol for Organic Synthesis: Pursuing Hydrogen Bonds and Hydrogen Transfer Process in Molecular Catalysis through Its Beyond

    THE 5th YOSHIMASA HIRATA MEMORIAL LECTURE 

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    Event date: 2010.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  101. AminoOrganoBoron (AOB) Complexes for Molecular Catalysis: Control of Hydrogen Transfer Process in Organic Synthesis International conference

    Susumu Saito

    The 4th ACP-ICCEOCA (International Conference Cutting-Edge Organic Chemistry in Asia) 

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    Event date: 2009.11

    Language:English   Presentation type:Oral presentation (invited, special)  

  102. New Platform for Controlling Hydrogen Transfer Process in Molecular Catalysis for Organic Synthesis International conference

    The 5th Sino-Japanese Symposium on Organic Chemistry for Young Scientists 

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    Event date: 2009.10

    Language:English   Presentation type:Oral presentation (invited, special)  

  103. アミノ有機ボラン錯体を用いる新しい酸ー塩基複合型触媒反応の開発

    第56回有機金属化学討論会 

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    Event date: 2009.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  104. アミノ有機/MOR系触媒を用いる水素移動の制御と有機合成

    丸岡特定領域研究「炭素資源の高度分子変換」特定取り纏めシンポジウム 

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    Event date: 2009.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  105. New Acid-base Cooperative Catalysis Using Aminoorganoboron Complexes International conference

    7th Joint IRTG Symposium for Nagoya-Mu¨nster University 

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    Event date: 2009.5

    Language:English   Presentation type:Oral presentation (invited, special)  

  106. Open Structure of Non-metal-Based Catalyst in Neutral pH Catalysis: Structure Dynamics between Monomer and Dimer Enabling Recombinant Hydrogen, Dative, and Covalent Bonds International conference

    Second Japan-Singapore Bilateral Symposium on Catalysis 

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    Event date: 2009.1

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  107. 強酸・強塩基触媒の化学から中性分子触媒化学への転換を目指して

    オルガノメタリックセミナーXXXIV「分子触媒化学の新パラダイム」 

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    Event date: 2008.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  108. 野依パラダイムから地球環境に優しい化学物質生産へ ~鍵となる物質:水素、水、二酸化炭素~

    斎藤 進

    日本技術士会東海支部冬季例会 

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    Event date: 2008.12

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  109. Activation of Alcohols by Molecular Catalysts for Efficient Organic Synthesis

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  110. 強酸・強塩基触媒の化学から中性触媒化学への転換を目指して

    岡山大学理学部講演会 

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    Event date: 2008.8

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  111. アミン系配位子/MOR型触媒を用いるエノラート種の生成と反応の新展開

    斎藤 進

    特定領域研究「炭素資源の高度分子変換」第5回公開講演会 

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    Event date: 2008.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  112. Making Transition from Strong Acid or Base Catalysis to Neutral Catalysis

    Susumu Saito

    Annual Symposium on Global COE in Chemistry 

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    Event date: 2008.6

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  113. Acid-base Alternating Molecular Catalysis-Design and Applications International conference

    4th Annual Symposium on Japanese-German Frontiers of Science 2007 

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    Event date: 2007.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  114. Design of Acid-base Catalysis for Organic Synthesis -Directed toward Direct Aldol Reaction of Organoamides- International conference

    IRTG Program for Nagoya–Münster Joint Seminar 

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    Event date: 2007.9

    Language:English   Presentation type:Oral presentation (invited, special)  

  115. 精密有機合成を指向した酸塩基交互配列型分子触媒反応の開拓と応用

    2007旭硝子財団成果報告会 

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    Event date: 2007.6

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  116. 「形ある水」を基盤とする触媒反応の開拓

    高砂香料工業特別講演会 

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    Event date: 2007.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  117. Enolate formation and reaction promoted by molecular catalysts based on well-designed water molecule(s) International conference

    The 10th International Kyoto Conference on New Aspects of Organic Chemistry 

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    Event date: 2006.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  118. 精密設計された酸-塩基相互作用と有機合成

    京都大学化学研究所客員助教授講演会 

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    Event date: 2004.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  119. 精密設計された酸-塩基相互作用と有機合成

    第9回名古屋大学理学部化学教室セミナー 

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    Event date: 2003.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  120. アルミニウム反応剤を用いるカルボニル化合物の(超)分子認識:ルイス酸の選択的配位とカルボニル化合物の立体配座制御に基づく精密有機合成

    豊田中央研究所 合成連絡会 

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    Event date: 2002.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  121. 超分子認識に基づくエノラート・イオンの生成と反応制御

    日本化学会第50回進歩賞受賞講演会 

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    Event date: 2001.3

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  122. 芳香族鉛化合物を用いる不斉アリ-ル-アリ-ルカップリング反応

    有機金属化学討論会 

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    Event date: 2000.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  123. Designer Aluminum Reagents for Selective Organic Synthesis International conference

    Susumu Saito

    Chemistry Department Seminar, Brandies University 

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    Event date: 2000.8

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  124. アルミニウムトリス(2,6-ジフェニルフェノキシド)(ATPH)を用いるエノラートの生成と反応の制御

    永島セミナー、九州大学機能物質科学研究所 

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    Event date: 2000.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  125. Mixed Aldol Condensation of Two Different Carbonyl Compounds Using Aluminum Tris(2,6-diphenylphenoxide) (ATPH) International conference

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    Event date: 1999.11

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  126. Aluminum Tris(2,6-diphenylphenoxide) (ATPH)を用いるエノラート単量体の創製とその有機合成への応用

    有機合成化学協会東海支部「若手研究者のためのセミナー 

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    Event date: 1999.6

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  127. 新しいルイス酸型レセプターATPHを用いるα,β-不飽和カルボニル化合物の捕捉、およびその有機合成への応用

    第28回有機金属若手の会 

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    Event date: 1995.7

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 12

  1. 二酸化炭素と水からsyngas(一酸化炭素+水素)を高効率に常温常圧合成する技術の実証 International coauthorship

    2018.10 - 2021.3

    酸化炭素の資源化を通じた炭素循環社会モデル構築促進事業 

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  2. 光照射下でも頑健な分子触媒の基盤構築とCO2資源化への展開

    2016.4 - 2022.3

    第1分野・ステップ研究助成 

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    Authorship:Principal investigator 

  3. 分子触媒と固体触媒のクロスオーバー領域の精密化に基づく二酸化炭素の資源化法の開拓

    2012.10 - 2017.9

    科学技術振興機構(JST)先導的物質変換領域(ACT-C) 

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    Grant type:Competitive

  4. CO2の水中電気還元に有効な金属錯体-炭素電極の高耐久性を目指した不活性化機構の解析と解明

    Grant number:22IMS1101  2022.4 - 2023.3

    共同利用研究 課題研究(通年・前期)  

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000

  5. ランダムフォレストを活用したフォトレドックス触媒反応における機械学習モデルの開発

    2021.10 - 2022.9

    2021年度 産総研-名大アライアンス事業 共同研究 

    納戸直木、斎藤進(名古屋大学)、矢田陽(産総研)

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    Grant type:Competitive

    Grant amount:\1200000

  6. 水を不斉反応場とする低環境負荷型アミノ酸合成プロセスの開拓

    2021.4 - 2022.3

    自然科学研究機構(IMS)  自然科学研究機構分野融合型共同研究事業(分野融合型共同研究) 

  7. CO2からMeOHへの省エネルギー変換法の開拓 分子触媒を用いるウレタン類の脱水的合成と水素化

    2012.4 - 2014.3

    自然科学第1分野・研究奨励 

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    Grant type:Competitive

  8. CO2の化学変換に関わる基礎研究

    2010.10 - 2011.9

    国内共同研究 

  9. 多官能性触媒化学の創製と応用

    2008.10 - 2010.9

    国内共同研究 

  10. 先端的基盤有機合成技術の開発

    2004.10 - 2006.9

    国内共同研究 

  11. 精密有機合成を指向した有機―無機ハイブリッド型典型金属触媒創製のための基礎研究

    2004.4 - 2006.3

    自然科学系研究助成 特定研究助成B 

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    Grant type:Competitive

  12. 次世代型触媒「有機典型金属ナノクラスター分子触媒」の機能発現を目指して

    2003.4 - 2004.3

    基礎科学研究助成 

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    Grant type:Competitive

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KAKENHI (Grants-in-Aid for Scientific Research) 17

  1. PNNP四座配位子をもつ金属錯体を用いる高効率的なCO2の光還元反応の開発

    Grant number:21F21338  2021.10 - 2023.9

    日本学術振興会  日本学術振興会 外国人特別研究員(一般) 奨励費  

    SeongHee Bae

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2400000

  2. Synthetic improvement of the basic principle for molecular hydrogenation catalysis of carboxylic acids

    Grant number:19H02713  2019.4 - 2023.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B)  Grant-in-Aid for Scientific Research (B)

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    Authorship:Principal investigator 

    Grant amount:\17160000 ( Direct Cost: \13200000 、 Indirect Cost:\3960000 )

  3. Catalytic triazophosphorine in tandem intermolecular and intramolecular dehydration of peptide formation and transformation

    Grant number:18F18339  2018.11 - 2021.3

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    Authorship:Other 

  4. One-pot reactions for synthesis of non-standard peptides by controlling hydrogen-transfer fields

    Grant number:18H04247  2018.4 - 2020.3

    Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

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    Authorship:Principal investigator 

    Grant amount:\6240000 ( Direct Cost: \4800000 、 Indirect Cost:\1440000 )

  5. Development of carbon-carbon bond formation between organic compounds and CO2 using semiconductor photocatalysis

    Grant number:16F16040  2016.10 - 2019.3

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    Authorship:Other 

  6. Dehydrative Formation and Transformation of Amino Acid Derivatives Using Well-designed Hydrogen Transfer Catalysts

    Grant number:16H01012  2016.4 - 2018.3

    Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

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    Authorship:Principal investigator 

    Grant amount:\5720000 ( Direct Cost: \4400000 、 Indirect Cost:\1320000 )

  7. 新触媒活性種「分子表面触媒」を用いる不活性アミドの水素化の深化

    Grant number:25105721  2013.4 - 2015.3

    新学術領域研究(研究領域提案型)

    斎藤 進

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    Authorship:Principal investigator 

    Grant amount:\7020000 ( Direct Cost: \5400000 、 Indirect Cost:\1620000 )

    アミドは、タンパク質やオリゴペプチド、N-アセチル糖類(グルコサミン、キチンなど)として自然界に豊富に存在する。ナイロン、ケブラーなどアミド系高分子として、およびアクリルアミド、カプロラクタムなど高分子合成用のモノマーとしても工業的に大量生産可能である。しかしながら不均一系触媒を用いる不活性アミドの水素化の既存法は一般的に、高PH2・高Tを必要とし選択性に乏しい。最近になり我々の研究と平行して錯体触媒を用いる幾つかの水素化が報告されたが、いずれの場合も主に「活性」アミドに有効である。N-フェニル-、N-アシル-、α-アルコキシアミドおよびモルホリノケトン、もしくは立体的に小さいアミドなどである。いずれも、アミド基の炭素求電子性を、電子的もしくは立体的に向上させるよう工夫された反応性に富むアミドである。反応性が異なる多彩なアミドの水素化には不均一系固体(金属)表面触媒と均一系金属錯体触媒、両者それぞれの長所を学術的に発掘し触媒開発に組み入れ「よいとこどり」した触媒が理想的だと考えた。不均一系触媒のよさは固体表面がもつ「高活性・構造的頑健性」、均一系触媒がもつよさは「高選択性・構造的柔軟性」にあるとまずは判断し、均一系金属錯体触媒の立場からEley-Ridealモデルを念頭に入れ取り組んだ。そのなかで、最近我々の研究グループが提案した概念「分子触媒表面:catalytic molecular surface」の開発とそれに基づく不活性アミドの水素化法を達成した。1級(1°)/2級(2°)/3級(3°)アミド、芳香族アミド/脂肪族アミド、小さいアミド/嵩高いアミド、鎖状アミド/環状アミド、など種類に関わらず反応は進行する。人工ナイロン系高分子、3つのアミド結合をもつペプチド鎖など、より高官能基化されたアミドの水素化も良好である。ある活性アミドの水素化ではTON ~8000程度を記録した。
    26年度が最終年度であるため、記入しない。
    26年度が最終年度であるため、記入しない。

  8. Zero emission CO2 transformation based on visible light irradiation

    Grant number:24655026  2012.4 - 2015.3

    SAITO Susumu

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    Authorship:Principal investigator 

    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

    We demonstrated that under visible light (> 400 nm) irradiation, CO2 was converted into CO and HCO2H using transition metal complexes bearing Ir, Ru or Co as a metal center coordinated with (P,N,N,P)-type tetradentate ligands. The highest turnover number recorded is around 20. It was also revealed that structural robustness (no decomposition of metal complex during light irradiation) should be more improved to ensure a higher TON. Direct conversion of CO2 to MeOH would be also possible in a future development of a higher performance molecular catalyst bearing a tetradentate ligand.

  9. 新触媒活性種創製に基づくアミドの触媒的水素化の開拓

    Grant number:23105518  2011.4 - 2013.3

    新学術領域研究(研究領域提案型)

    斎藤 進

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    Authorship:Principal investigator 

    Grant amount:\7020000 ( Direct Cost: \5400000 、 Indirect Cost:\1620000 )

    アミドは,ナイロン,ケブラーなどアミド系高分子,およびアクリルアミド,カプロラクタムなど高分子合成用のモノマーとしても工業的に大量生産可能である.タンパク質やオリゴペプチドとして自然界にも豊富に存在する.しかしながらアミド基はカルボニル基のなかで最も不活性であり,その水素化は速度論的にも熱力学的にも難しいとされてきた.アミドの水素化を実現する配位子には2つの特徴が求められる.第一にかさ高さ,第二に強い結合力である.これら二つの特徴を満たす配位子として(P,N)型二座配位子を選択した.我々は今回,そのような配位子をもつ新しい触媒前駆体Ru錯体を3種類開発した.なかでもRu錯体Cl2Ru(Cy2PCH2Py)2を触媒前駆体として用いることで,一般的な「不活性」アミドの選択的水素化に成功した.本手法は高い基質一般性を示し,1級アミド,2級アミド,3級アミドに有効である.鎖状のより不活性なアミドのみらなず,環状アミドにも適用可能である.反応機構を調べるなかで,触媒誘導段階でCl2Ru(Cy2PCH2Py)2の配位子のピリジン部位が完全に水素化されピペリジンになることも示された.すなわち配位子であるCy2PCH2PyがCyPCH2(piperidine)になったものが実際の触媒活性種に関わっていることを突き止めた.その結果,触媒誘導段階にのみ高温,高H2圧が必要で,実際のアミドの水素化でははより低温・低PH2(120 °C, 2 MPa)で十分であることを発見した.水銀テストによってRuナノパーティクルの触媒としての作用もほぼ無視できるため,H-Ru-N-H構造の構築に基づく「新触媒活性種」の二官能性機構を支持する有力な 情報を得たといえる.
    24年度が最終年度であるため、記入しない。
    24年度が最終年度であるため、記入しない。

  10. New Aspects of Catalytic Trans form ation of Alcohols Using Metal Alkoxides Having Protic Ligands

    Grant number:21350052  2009 - 2011

    SAITO Susumu

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    Authorship:Principal investigator 

    Grant amount:\18980000 ( Direct Cost: \14600000 、 Indirect Cost:\4380000 )

    The research project was focused on how we could control and alter the reactivity of alcohols as electrophile(R^+-^OH) nucleophile(R^+-^OH) using new molecular catalyses in organic synthesis. Importance of a new concept“molecular surface"in those catalyses was newly introduced and validated during the project. Overall, we demonstrated that molecular surface consisting of special element and bond alignment as represented by RO(δ-)-M(δ+)-X(δ-)-H(δ+) is important to achieve otherwise difficult catalysis under near neutral pH conditions.

  11. Advanced Eno I ate Formation and Reaction with Small Carbon Resources Catalyzed by Aminoorganometal Complexes

    Grant number:17065007  2005 - 2008

    SUSUMU Saito

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    Authorship:Principal investigator 

    Grant amount:\18100000 ( Direct Cost: \18100000 )

  12. 有機典型金属-アミン型触媒を用いる分子の集合化と新しい触媒作用の創製

    Grant number:16685010  2004 - 2006

    斎藤 進

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    Authorship:Principal investigator 

    Grant amount:\28340000 ( Direct Cost: \21800000 、 Indirect Cost:\6540000 )

    近年の有機合成化学の発展は、低分子から高分子に渡る多彩な化学物質の合成を可能にした。しかし、出発原料から目的物のみを得るという理想的な反応の開発には、いまだ未踏の領域が多い。革新的な有機合成の発展に寄与する今後の研究には、学術的な興味のみならず、枯渇に瀕した金属・化石資源に対する意識も必然的に求められる。そこで、前年度に引き続き、ユビキタス元素からなる触媒の開発研究を行った。とくに、典型元素とアミン、そして水分子から成るアミノ有機ボラン-水型触媒や、その類似体であるアミノ有機シラノール化合物、およびテトラゾイルシラノール触媒の反応適用範囲の拡大を目指した。触媒作用の特徴としては、元素中心の内圏ではなく外圏を主に活用する点や、元素中心によって活性化さ媒は複数の酸と塩基が協同的に働く多機能性をもつが、同時に高機能性をも示す。これら触媒のひとつは、エポキシドの過溶媒分解において、TON=9700を記録した。ボランを中心元素としてもつ水分子触媒に関しては、ニトロアルドール反応のみならずDirectアルドール反応にも適用できることが証明された。アルコールの水酸基の酸性度を識別するアセチル化触媒としても機能する。この触媒を用いて、ニトロアルドール反応における詳細な速度論的実験を行った。その結果、「形ある水」分子がニトロ基を認識し、弱い相互作用をこの官能基と作るとともに、ニトロネートを可逆的に発生させることを突き止めた。また触媒とニトロアルカンそれぞれの濃度に対して1次反応であることを明確にした。触媒活性中心に存在するH_2O分子をD_2O分子に置換した触媒を用いてさらに反応速度を追跡したところ、D_2O分子がもつ、より高い触媒活性を確認できた。天然酵素は正逆両方の反応を促進するが、本触媒においても反応条件によっては逆ニトロアルドール反応も効果的に進行することが明らかとなった。まさに人工酵素ともよべる触媒系を構築できたといえる。そしてこの触媒のもつ水部位が触媒活性の発現に必須であることを証明した。

  13. Exploitation of Fine Molecular Catalysts

    Grant number:14GS0214  2002 - 2006

    Grant-in-Aid for Creative Scientific Research

    NOYORI Ryoji

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    Authorship:Coinvestigator(s) 

    (1) Asymmetric Hydrogenation of Ketones: Chiral RuC1_2(binap)(1, 2-diamine) complexes allow rapid, enantioselective hydrogenation of various simple, unfunctionalized ketones with a high substrate/catalyst molar ratio up to 2, 400, 000. As high practicality of this procedure became recognized, we have been encouraged to develop a robust (pre)catalyst that promotes the enantioselective reaction under base-free conditions. During the course of this program, we established that RuH(η^1-BH_4)(binap)(1, 2-diamine) complexes allow for asymmetric hydrogenation of simple ketones in 2-propanol without an additional strong base. Various base-sensitive ketones are convertible to chiral alcohols in a high enantiomeric purity. More recently, we discovered that N-tosylethylenediamine-Ru(II) complexes catalyze asymmetric hydrogenation of ketones giving the corresponding chiral carbinols in high enantiomeric purity. These Ru(II)-complexes, known as excellent catalysts for asymmetric transfer hydrogenation, can be used for asymmetric hydrogenation as well. This discovery provides a long-thought method for enantioselectively hydrogenating simple ketones under nonbasic and acidic conditions. Further kinetic studies, isotope labeling experiments, and a set of different ID and 2D NMR analyses as well as computational analysis supported a metal-ligand bifunctional mechanism passing through a six-membered pericyclic transition state. We believe the present bifunctional molecular catalyst offers a great opportunity to open up new fundamentals for stereoselective molecular transformation.
    (2) Creation of Acid-Base Catalysis Involving Water Functions: Compared with functional group conversions attained by many types of atom-economical oxidation and/or reduction methods, efficient catalysis that mediates carbon-carbon bond formation still remains a considerable challenge. In particular, the development of mild and efficient transformations involving enol and enolate equivalents in the presence of a molecular catalyst has been a topic of continuous interest in organic synthesis. Several drawbacks that come from a high catalyst loading, low atom economy and generation of undesirable by-products need improvement. In order to sustain high reactivity to achieve maximum conversion, future catalysts should be structurally stable with catalytic species that are inert to the air and water. Such catalysts should be also capable of discriminating and binding to a single functionality for complex, multi-functional group substrates. Recently we discovered a novel molecular catalyst that shows high catalytic activity through molecular recognition events. These catalysts have aqua-cluster structures composed of aminoorganoboron and water. The structural properties of these catalysts are very unique: only one water molecule is captured by the combination of two hydrogen bonds and one coordination bond. We proposed that a special arrangement of the water molecule and multiple amines within the catalyst serves as a catalytically active site, thereby mimicking enzyme-like activity by forming cooperative acid-base interactions with organic substrates.
    (3) Direct Carbon-hydrogen Bond Arylation: Organic molecures having (hetero)aryl-(hetero)aryl bonds represent privileged structural motifs frequently found in natural products or used in pharmaceuticals as well as functional organic materials. Therefore, the development of efficient methods for biaryl has been a topic of unparalleled importance in all aspects of pure and applied chemistry. Although metal-catalyzed cross-coupling reactions of organometallics and organic halides have enjoyed widespread applications, the direct C-H arylation of heteroarenes and arenes holds significant synthetic potential as it eliminates pre-activation of coupling components. As a part of our program aimed at establishing programmable synthesis of (hetero)aryl-core starburst molecules, we developed a new transition metal catalyst for direct C-H arylation of heteroarenes that manifested high activity paired with broad scope. The fact that our effort has culminated in the finding of direct C-H arylation of simple arenes speaks well for the potential of the present catalysis for further development and applications. Elucidation of reaction mechanism development of more active catalysts, and applications of present direct arylation technology for materials and pharmaceutical chemistry are currently ongoing.

  14. ATPHを用いる嵩高いエノラート・イオンの調製とその反応性・選択性に関する研究

    Grant number:12750749  2000 - 2001

    奨励研究(A)

    斎藤 進

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    Authorship:Principal investigator 

    Grant amount:\2200000 ( Direct Cost: \2200000 )

    エノラート前駆体であるカルボニル基にあらかじめデザイン型ルイス酸アルミニウム トリス(2,6-ジフェニルフェノキシド)(ATPH)による超分子修飾を施してカルボニル分子の性質を認識させ(超分子認識)、その後生成する新しい構造と機能をもつエノラート・イオンを用いて、効率的な選択的有機合成を実現した。具体的には、本年度は以下の成果をあげた。
    (1)ATPH-α,β-不飽和シクロペンタノン錯体、BCl_3-DHF錯体およびリチウム反応剤を組み合わせることで、新しい3成分連結反応の開発に成功した。特に、リチウムアセチリドを用いたときに生ずる超分子エノラートを用いて従来法では得られないシス選択性が得られた。このことを利用して、香料の成分であるエピジャスモン酸メチルの効率的な合成に成功した。
    (2)ATPHのα,β-不飽和カルボニル化合物の分子認識能をより詳細に調べた。単結晶X線構造解析と、^1H NMR実験、NOE実験を組み合わせて、ATPH-カルボニル錯体の構造と立体配座の傾向を明らかにした。また、この錯体の脱プロトン化によって生じるジエノラートの構造と立体配座についても同様に調べた。この結果、ATPHのもつ立体的・電子的特性がカルボニル化合物やジエノラートに及ぼす影響が明らかとなった。
    (8)ATPHのキラル分子認識能についても調べた。具体的には、キラルなα,β-不飽和エステルをATPHによって錯形成させ、その錯体の構造的特性を明らかにした。ATPHは動的なラセミ体構造をもつが、キラルエステルに配位することで、片方のキラリティに偏ることが分かった。このようにして誘導されたATPHの立体配座キラリティを利用して、不斉マイケル付加に応用したところ、Cu反応剤とは全く逆のジアステレオ選択性でマイケル付加体が得られることを見いだした。

  15. ATPHを用いるα、β-不飽和カルボニル化合物の高選択的1、4-不斉還元反応の開発

    Grant number:08750983  1996

    奨励研究(A)

    斎藤 進

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    Authorship:Principal investigator 

    Grant amount:\1100000 ( Direct Cost: \1100000 )

    当研究室で開発された新規ルイス酸型レセプター、アルミニウム トリス(2,6-ジフェニルフェノキシド)(ATPH)はキャビティを有するアルミニウム反応剤であり、ルイス塩基と酸塩基複合体を形成する際に、基質の微妙な立体的差異を認識したり、取り込まれた基質はキャビティを形成する3つのフェニル基の立体的、および電子的効果を受けて特異な反応性を示す。これらの効果によってATPHは、α,β-不飽和カルボニル化合物との酸塩基複合体形成の際に、様々な求核攻撃からカルボニル基を保護することが分かっている。この結果は、反応剤の合理的な設計が精密有機合成において重要であることの一つの証明であり、今回、ATPHを用いる手法の更なる応用として、α,β-不飽和カルボニル化合物の高選択的1,4還元とその不斉合成への応用を行った。
    1)今回の還元系ではATPHがα,β-不飽和カルボニル化合物のカルホニル基に配位しているため、アート錯体型還元剤が有効であると推測された。実際に、ATPHとの組み合わせにおいて最も相性の良かったのはn-BuLiとDIBAL-Hのアート錯体型還元剤であった。
    2)次に、様々なα,β-不飽和ケトンの還元を試みたところ、いずれの計においても、>99%以上の位置選択性と>95%以上の化学収率で1.4-還元体が得られた。
    3)続いてα,β-不飽和アルデヒドについても検討したところ、還元剤としてはt-BuLiとDIBAL-Hの組み合わせが有効であることが分かった。特に光、熱、酸などに不安定なレチナ-ルの高選択的1,6-還元に成功したことは,今後必要となるレチナ-ルの選択的官能基化に先駆けるものとして注目に値する。
    4)1)、2)、3)から得られてくる知見を基にこれまでにない新たな不斉1,4還元反応の実現を目指した。今回の還元系では、不斉源を還元剤側に導入した。すなわち、ATPHとカンファーから誘導したアート錯体型キラルアルミニウム還元剤を用いて3-メチルシクロヘキセノンの1,4-還元を行ったが、不斉誘導はほとんど起こらなかった。

  16. Development of Highly Slective Reactions Using Allylic Barium Reagents

    Grant number:07555286  1995 - 1996

    YAMAMOTO Hisashi

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    Authorship:Coinvestigator(s) 

    The organomatallic compounds of heavier alkaline earth metals have found little application in organic synthesis, since they do not offer any advantages over Grignard reagents. We have been interested in using barium or strontium reagents with the anticipation that such species should exhibit markedly different stereochemical stability from that the ordinary magnesium reagent. We have already reported that the allylic barium reagents can be easily prepared from in situ generated reactive barium and allylic chlorides, and react with a variety of carbonyl compounds at-78゚C to produce the homoallylic alchols with remarkably high alpha-selectivity and retention of the configuration of the starting chloraide.
    In this research, we further examined the reactions of allylic barium reagents with other electrophiles and thus highly alpha-selective allylation reactions with allylic halides, epoxides, and imines were found. Noteworthy was the fact that aldimines were transformed into homoallylic amines by treatment with allylic barium reagents in which both the alpha-and gamma-adducts were selectively obtained by simply changing the reaction temperature. Bis(2,2,2-trifluoroethyl)phoshate was found to be a superior leaving group for alpha, alpha'-selective cross-coupling reaction of allylic alcohol derivatives with allylic barium reagents. Selective Barbier-type cross-coupling reation was also achieved using this leaving group. For example, when a 1 : 1 mixture of (E) -2-octenyl 1-bis (2,2,2-trifluoroethyl) phosphate and (E) -2-decenyl chloride was teated with 1 equiv of reactive barium, the cross-coupling products were obtained with 86% selectivity and an alpha, alpha'/alpha, gamma' ratio of 94 : 6 . For practical use, largescale carboxylation of an allylic barium reagent was also investigated and over 70% yield of the product was constantly obtained in the 7 mmol-scale reaction.

  17. Development of a new molecular recognition chemistry using Lewis acidic receptors

    Grant number:06403024  1994 - 1996

    YAMAMOTO Hisashi

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    Authorship:Coinvestigator(s) 

    The fascination of molecular recognition chemistry is extending continuously, especially as host-guest systems which mimic biologically occurring compounds exhibiting catalytic activities like enzymes. The discovery of crown ethers and cryptands and their inclusion systems by Prof. Lehn and Cram led them to be the winners of the Nobel Prize, and most of these systems are constituted by hydrogen-bonding networks between host and guest molecules. Comparing with these weak interactions, relatively strong coordination bonding between Lewis acidic receptors and Lewis bases has received less attention for molecular recognition, and has never been used for selective organic synthesis.
    In this context, we have developed several bulky organoaluminum reagents which have sterically hindered phenoxide ligands. These bulky aluminum reagents are monomeric in solution, thereby possess strong Lewis acidity to bind a variety of heteroatom-containing substrates such as carbonyl, carboxyl and amide compounds. The complexation is sometimes stereo-, regio-, and chemoselective, leading to selective organic reactions which could not be realized with other ordinary Lewis acicls such as AlCl_3, SnCl_4, BF_3, and TiCl_4. In particular, aluminum tris(2,6-diphenylphenoxide(ATPH) was explored recently for obtaining unprecedented reactivity and selectivity n several reactions. 1. Conjugate addition of carbanions to alpha, beta-unsaturated aldehydes 2. Exo-selective Diels-Alder reactions 3. Stereo-and asymmetric Claisen rearrangement 4.1,6-Addition to aromatic carbonyl substrates.

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Industrial property rights 22

  1. カルボン酸化合物の水素化によるアルコールの製造方法、 及び該製造方法に用いるルテニウム錯体

    斎藤進,野依良治,鳴戸真之

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    Application no:特願2015-081711  Date applied:2015.4

    Country of applicant:Domestic  

  2. カルボン酸化合物の水素化によるアルコールの製造方法、 及び該製造方法に用いるルテニウム錯体

    斎藤進, 野依良治, 鳴戸真之

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    Application no:特願2015-081711  Date applied:2015.4

  3. 配位子,その配位子を含む金属錯体,及びその金属錯体を 用いた反応

    斎藤進,野依良治,三浦隆志,鳴戸真之,飯田和希,高田雄貴, 戸田勝章,二村聡太,Santosh Agrawal,Sunkook Lee

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    Application no:PCT/JP2014/55510  Date applied:2014.3

    Country of applicant:Domestic  

  4. カルボン酸化合物及びエステル化合物の水素化によるアルコールの製造方法

    斎藤進,野依良治,Santosh Agrawal,鳴戸真之

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    Application no:特願2013-268047  Date applied:2013.12

    Country of applicant:Domestic  

  5. カルボン酸化合物の水素化によるアルコールの製造方法,及び該製造方法に用いるルテニウム錯体

    斎藤進,野依良治,鳴戸真之

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    Application no:特願2013-267866  Date applied:2013.12

    Country of applicant:Domestic  

  6. 3級アミン又は3級アミン誘導体の製造方法

    斎藤進,野依良治,中寛史,Vasily Tsaraev, Joaquim Caner

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    Application no:特願2013-193470  Date applied:2013.10

    Country of applicant:Domestic  

  7. 有機化合物の製造方法

    斎藤進,野依良治,中寛史,Joaquim Caner, Zijun Liu

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    Application no:特願2013-193470  Date applied:2013.9

    Country of applicant:Domestic  

  8. 環状ウレタンの製造方法

    斎藤進,野依良治,中寛史,Siong Wan Foo

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    Application no:特願2013–65083  Date applied:2013.3

    Country of applicant:Domestic  

  9. 配位子,その配位子を含む金属錯体,及びその金属錯体を 用いた反応

    藤進,野依良治,三浦隆志,鳴戸真之,飯田和希,高田雄貴, 戸田勝章,二村聡太,Santosh Agrawal,Sunkook Lee

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    Application no:特願2013-42385  Date applied:2013.3

    Country of applicant:Domestic  

  10. カルボニル化合物の製造方法

    野依良治,斎藤 進,中寛史,Zijun Liu,Joaquim Caner

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    Application no:特願2012–181888  Date applied:2012.8

    Country of applicant:Domestic  

  11. ウレタンの製造方法

    野依良治,斎藤 進,中寛史,山崎祐輔,高田雄貴

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    Application no:特願2012–70113  Date applied:2012.3

    Country of applicant:Domestic  

  12. ウレタンの製造方法

    野依良治,斎藤 進,中寛史,山崎祐輔,Siong Wan Foo

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    Application no:特願2012–28845  Date applied:2012.2

    Country of applicant:Domestic  

  13. ルテニウム錯体、水素移動反応用触媒及び水素移動反応物の製造方法

    斎藤 進,野依良治,三浦隆志,Ingmar Held,鈴木めぐみ,飯田和希,高田雄貴

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    Application no:PCT/JP2012/51373   Date applied:2012.1

    Country of applicant:Domestic  

  14. ルテニウム錯体、水素移動反応用触媒及び水素移動反応物の製造方法

    斎藤 進,野依良治,三浦隆志,Ingmar Held, 鈴木めぐみ,飯田和希

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    Applicant:国立大学法人 名古屋大学

    Application no:特願2011–12316  Date applied:2011.1

    Country of applicant:Domestic  

  15. 炭酸エステルの製造方法

    野依良治、斎藤 進、中 寛史、山崎祐輔、Ya Du

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    Applicant:国立大学法人 名古屋大学

    Application no:特願2010-203712  Date applied:2010.9

    Country of applicant:Domestic  

  16. ピロールの製造方法

    野依良治、斎藤 進、中 寛史、小瀬修、安藤潤紀

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    Applicant:国立大学法人 名古屋大学

    Application no:特願2010-49823  Date applied:2010.3

    Country of applicant:Domestic  

  17. 液相でラクトンおよびカルボン酸エステルを水素化するアルコール類の製造方法

    野依良治、斎藤 進、(株)カネカ、(株)高砂香料工業

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    Applicant:名古屋大学、(株)カネカ、(株)高砂香料工業

    Application no:特願2007-97618  Date applied:2007.4

    Country of applicant:Domestic  

  18. α-アミノオキシケトン化合物及びα-ヒドロキシケトン化合物の製造方法

    斎藤 進

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    Applicant:科学技術振興事業団

    Application no:PCT/JP2005/002163  Date applied:2005.2

    Country of applicant:Foreign country  

  19. Process of making α-aminooxyketone/ α-aminooxyaldehyde and α-hydroxyketone/α-hydroxyaldehyde compounds and a process of making reaction products from cyclic α,β-unsaturated ketone substrates and nitroso substrates

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    Application no:PCT/US05/005426  Date applied:2005.2

    Country of applicant:Foreign country  

  20. α-アミノオキシケトン化合物およびα-ヒドロキシケトン化合物の製造方法&#8232;

    斎藤 進

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    Applicant:独立行政法人 科学技術振興機構

    Application no:特願2004―044540  Date applied:2004.2

    Announcement no:特開2005-232100 

    Date registered:2005.9 

    Country of applicant:Domestic  

  21. ヒドロキシケトン化合物の製造方法

    斎藤 進

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    Applicant:科学技術振興事業団

    Application no:特願2003-054697  Date applied:2003.2

    Announcement no:特開2004-262826 

    Date registered:2004.9 

    Country of applicant:Domestic  

  22. 芳香族不斉カップリング反応方法

    斎藤 進、山本 尚

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    Applicant:科学技術振興事業団

    Date applied:1999.8

    Announcement no:特許平11-240527号 

    Date registered:2001.3 

    Country of applicant:Domestic  

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Teaching Experience (On-campus) 10

  1. Advanced Organic Chemistry

    2020

  2. Core Organic Chemistry

    2020

  3. Current Organic and Polymer Chemistry

    2020

  4. Core Organic Chemistry

    2019

  5. Core Organic Chemistry

    2018

  6. 高等研究院初年次教育「学問のおもしろさを知る」

    2012

  7. 有機化学特論

    2012

  8. 有機化学特論I

    2012

  9. 有機化学特論I

    2011

  10. 有機化学特論I

    2011

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Social Contribution 80

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    2014.10

  11. Noyori Academy Salon: Scientists and Artists

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.9

  12. Noyori Academy Salon: Science and Politics

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.7

  13. Noyori Academy Salon: Transition in the Value of Science

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.6

  14. Noyori Academy Salon: Earthquake prediction

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.5

  15. Noyori Academy Salon: Science is Unshakable

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.4

  16. Noyori Academy Salon: Science and Technology

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.2

  17. Noyori Academy Salon: the mission of scientists

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2014.1

  18. Noyori Academy Salon: The Meaning of Life

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2013.12

  19. Noyori Academy Salon: Nobel Prize and World-leading Nation in Science

    Role(s):Media coverage, Chief editor, Editer, Advisor, Planner, Organizing member, Report writing

    2013.11

  20. 名古屋大学レクチャー2012 青色LEDが拓いた光の革命

    2012.10

  21. 名古屋大学レクチャー2012 日本文学と日本文化をめぐって語る

    2012.2

  22. 第3回高等研究院アカデミーサロン ノーベル物理学賞益川敏英特別教授が贈る特別記念講座「CP対称性とは?」

    2011.12

  23. 野依良治先生書籍販売記念サイン会+若手との談話会「野依先生に質問しよう」の企画運営

    2011.8

  24. 第1回高等研究院アカデミーサロン ノーベル化学賞受賞野依良治博士が贈るES館開館記念特別講座「不斉とは?基礎講座」

    2011.8

  25. 第6回高等研究院レクチャー

    2011.3

     More details

    環境学という学問は、何でしょうか?環境学を医学に例えて説明します。ある地域の「環境問題」とは人体の一部分の「病気」に相当します。環境学とは、環境の病を「診断」し「治療」するためのものです。環境の問題究明と救命には、「診断型」と「治療型」双方の研究が必要です。地域の環境の診断と治療に責任をもってあたるのが「臨床環境学」。臨床を支える共通の基盤を、地域の問題をまたいで構築していくのが「基礎環境学」。これら二本の環境学の柱をもっと大きな地域環境問題の架け橋とし、診断と治療もしっかりとつないでいく必要があります。第6回高等研究院レクチャーでは、名古屋大学環境学研究科の先鋭研究者、中塚武先生、横山智先生、加藤博和先生の3名がそれぞれの話題を通じて、基礎と臨床の環境学のコラボによって拓かれる最先端の環境学を解説します。環境学という学問の創造にむけて、名古屋大学グローバルCOEプログラム(GCOE)「地球学から基礎・臨床環境学への展開」では、真摯にかつ果敢に環境問題に挑戦し続け、世界屈指の成果を着々とあげています。GCOEリーダーの安成哲三先生を招聘、一般に向けても公開

  26. 名古屋大学レクチャー2010_2

    2010.11

     More details

    岸 義人教授(米国・ハーバード大学特任教授名古屋大学特別教授
    文化功労者)、中西 香爾教授(米国・コロンビア大学教授
    名古屋大学特別教授、文化勲章受章者)を招聘し、一般に向けて公開

  27. 岐阜県立鴬谷高等学校「出前講義」

    2010.11

  28. 第4回高等研究院レクチャー

    2010.5

     More details

    すべての病気は、本来正常に働くべき生命機能が破綻することで起こってきます。生命を機械に例えれば、いろいろな場所が故障することで病気になるわけです。この生命機械を形作っているのが細胞であり、そしてさらに突き詰めていくと分子にまでたどり着きます。これらは、どのようにお互い連絡をとりながら働いているのでしょうか?そして、病気の時にはどんな連絡役がどのように故障しているのでしょうか?また、生命機械と人工機械とはどのように違うのでしょうか?第4回高等研究院レクチャーでは、これらの問いに、Rhoファミリーという細胞間の連絡役の研究で世界をリードする名古屋大学の貝淵弘三教授と、生命を分子機械として解き明かす極めて独創的な研究で知られる大阪大学の柳田敏雄教授にを招聘、一般に向けて公開

  29. 第3回高等研究院レクチャー

    2010.3

     More details

    宇宙には謎のキープレーヤー達がたくさんいます。今回のテーマ『宇宙への挑戦。』では消えてしまった反粒子、太陽が引き起こす宇宙の嵐、惑星や有機物を生み出すもととなった宇宙塵が主役を演じます。名古屋大学グローバルCOE「宇宙基礎原理の探求」においては真摯にかつ果敢に宇宙の謎に挑戦し続け、その全容解明に向け世界屈指の成果を着々とあげています。今回の高等研究院レクチャーでは、素粒子実験の若手リーダー飯嶋博士、高等研究院ホープの関博士、赤外線天文学を先導する金田博士、GCOEリーダーの杉山博士に講師として招聘、一般に向けて公開

  30. 2010年名古屋大学レクチャー

    2010.3

     More details

    講師:杉浦 昌弘教授(名古屋大学名誉教授)、竹市 雅俊教授(理化学研究所発生再生科学総合研究センター長)を招聘し一般に向けて公開

  31. 静岡県立韮山高等学校「大学レクチャー」

    2009.12

  32. 第1回高等研究院レクチャー

    2009.3

     More details

    今まで、事故などで神経が損傷すると回復しないと考えられていました。しかしながら最近の研究から神経細胞も体の中で再生できることがわかり、神経再生のためのさまざまな研究が進んでいます。今回の高等研究院レクチャーでは、ES細胞や最近話題のiPS細胞を用い、神経再生医療の実現に向け研究を推進している慶應義塾大学医学部の岡野栄之教授に講師として招聘、一般にも向けて公開

  33. 2008年ノーベル化学賞受賞記念 名古屋大学レクチャー

    2009.3

  34. NHKテレビ放送局番組「ノーベル賞受賞者と若手が語る会」の収録協力

    2009.2

     More details

    小林 誠博士、益川 敏英博士、野依良治博士という3名のノーベル賞受賞者をお招きし、高校生や中学生との対話形式で開催されたテレビ番組の収録のアレンジを支援した。

  35. 2008年ノーベル物理学賞受賞記念 名古屋大学レクチャー

    2009.2

  36. 愛知県立小牧南高等学校「大学の授業体験」

    2008.9

  37. 東海ラジオ放送局日曜番組「サンデーインザパーク」収録協力

    2008.7

     More details

    飯島澄男教授のラジオ番組出演のアレンジとナノカーボンの面白さを一般に向けて発信する活動の支援

  38. 名古屋大学レクチャー2008

    2008.7

     More details

    飯島 澄男教授(名古屋大学特別招へい教授/
    名城大学教授)およびハロルド・W・クロトー教授(米フロリダ州立大学教授、ノーベル化学賞受賞者)を招聘し一般向け講演会を開催

  39. 名古屋大学レクチャー2006

    2006.10

     More details

    ミシェル・ザンク(フランス学士院会員
    コレージュ・ド・フランス副学長)を招聘し
    「西洋における詩歌の一源泉ー中世吟遊詩人の歌とその解説書ー」という演題で
    一般向け講演会を開催

  40. 岐阜県立多治見高等学校「出前講義」

    2006.10

  41. 第22回野依サロン話題「オンリーワンとナンバーワン」

    Role(s):Planner

    名古屋大学高等研究院 

  42. 第21回野依サロン話題「掛け算が質をかえる」

    Role(s):Planner

    名古屋大学高等研究院 

  43. 第20回野依サロン話題「文化を尊ぶ文明」

    Role(s):Planner

    名古屋大学高等研究院 

  44. 環境と資源の危機を 「触媒」で乗り超える

    Role(s):Informant

    日本科学技術振興機構 JST News 

     More details

    Audience: General

    Type:Promotional material

  45. 安定アミドを効率よくアミンやアルコールに変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    Role(s):Informant

    日本の研究.com 

  46. 安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    Role(s):Informant

    J-Net21 中小企業ビジネス支援サイト 

  47. 安定アミドを効率よくアミンやアルコールにい変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    Role(s):Informant

    日本科学技術振興機構 プレスリリース 

  48. 安定アミドを効率よくアミンに変換する触媒 名大グループが開発

    Role(s):Informant

    科学新聞 

  49. 天然に豊富なカルボン酸を効率よくアルコールに変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    Role(s):Informant

    日本科学技術振興機構 プレスリリース 

  50. 名大リバケは未来の化学

    Role(s):Lecturer

    名古屋大学理学部化学科 

  51. 名古屋大学など,安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    Role(s):Informant

    日本経済新聞(online) 

  52. 名古屋大学など、低温/低水素圧で安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    Role(s):Informant

    fabcross for エンジニア 

  53. 名古屋大学、炭素循環社会を実現する安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    Role(s):Informant

    炭素ニュース 

  54. 不活性炭素資源の活用法

    Role(s):Lecturer

    名古屋大学理学部化学科 

  55. タイトル:カルボン酸をアルコール変換する革新的な水素化触媒を開発 〜レニウムを用いる計画的なアルコールの合成がもたらす炭素循環社会に期待〜

    Role(s):Informant

    名古屋大学 

  56. カルボン酸を触媒のみでアルコールに変換

    Role(s):Informant

    Chem Station 

  57. カルボン酸を効率よくアルコールに変換 名大 複製物少ない触媒開発 炭素循環型社会の実現に貢献期待

    Role(s):Informant

    科学新聞 

  58. カルボン酸からアルコールへ変換 名大が高性能触媒開発

    Role(s):Informant

    日刊工業新聞 

  59. アミド向け触媒開発 アミンやアルコールに効率変換 名大

    Role(s):Informant

    日刊工業新聞 

  60. Researchers break down under mild conditions

    Role(s):Informant

    Financial Express 

  61. Researchers Break down Plastic Waste _ Nagoya University-based research team develops new highly efficient catalyst for breaking resistant chemical bonds, paving the way for easier recycling of plastic waste

    Role(s):Informant

    Lab Manager 

  62. Researchers break down plastic waste

    Role(s):Informant

    Phys.Org 

  63. Newly-developed compound will be able to break down plastic waste! _ Although amide bonds can give great strength to plastics, when it comes to their recycling at a later point, the difficultly of breaking these bonds usually prevents recovery of useful p

    Role(s):Informant

  64. Newly-developed compound will be able to break down plastic waste! _ Although amide bonds can give great strength to plastics, when it comes to their recycling at a later point, the difficultly of breaking these bonds usually prevents recovery of useful p

    Role(s):Informant

    Zeenews 

  65. New Highly Efficient Catalyst for Breaking Resistant Chemical Bonds Simplifies Recycling of Plastic Waste

    Role(s):Informant

    AzocleanTech 

  66. New catalyst paving the way for easier recycling of plastic waste

    Role(s):Informant

    Nanowerk 

  67. Nagoya University researchers succeed in breaking down plastic waste in an easier way

    Role(s):Informant

    Crazy Engineers (記者署名入りの書き下ろし記事あり) 

  68. Nagoya University Researchers Break Down Plastic Waste _ Nagoya University-based research team develops new highly efficient catalyst for breaking resistant chemical bonds, paving the way for easier recycling of plastic waste.

    Role(s):Informant

    Asia Research News 

  69. Nagoya University chemists turn metal catalysis on its head for a sustainable future _ Nagoya University researchers take a nonintuitive approach to metal catalysis for selective conversion of biomass into high-value chemical products under mild condition

    Role(s):Informant

    EurekAlert! | AAAS 

  70. Japanse onderzoekers hebben organorutheniumkatalysatoren ontwikkeld die amides kunnen afbreken, dus misschien ook nylon. Dat melden ze in Nature.

    Role(s):Informant

    C2W(記者署名入りの書き下ろし記事あり) 

  71. Hacia un proceso pr_ctico para descomponer pl_stico

    Role(s):Informant

    NCYT Noticias de la Clencai y la Technologia 

  72. Effective Method of Decomposing Plastic Waste (https://spinoff.com/plasticdecomp)

    Role(s):Informant

    spinoff.com, UK 

  73. CO2からアルコールへ 名大が新触媒 資源化期待

    Role(s):Informant

    中日(朝刊) 

  74. Breaking down plastic waste Organo-ruthenium mediated hydrogenation under mild conditions

    Role(s):Informant

    ChemEurope.com 

  75. According to the study, organometallic ruthenium catalysts may break down even the toughest amide bonds effectively under mild conditions.

    Role(s):Informant

    DNA daily news and analysis (ANI) 

  76. A Mild Way To Break Down Plastic Waste

    Role(s):Informant

    AsianScientists 

  77. 第23回野依サロン話題「欠乏という豊かさ」

    Role(s):Planner

    名古屋大学高等研究院 

  78. 第25回野依サロン話題「女性の社会参画」

    Role(s):Planner

    名古屋大学高等研究院 

  79. 第25回野依サロン話題「みらいを作る力」

    Role(s):Planner

    名古屋大学高等研究院 

  80. 第24回野依サロン話題「人類存続に貢献する日本」

    Role(s):Planner

    名古屋大学高等研究院 

▼display all

Media Coverage 83

  1. アルコール取り出す効率良い触媒を開発 名大チーム バイオマス資源で成果

    中日新聞社  中日(朝刊)+online  https://www.chunichi.co.jp/article/142505  2020.10

  2. An Effective Method of Decomposing Plastic Waste

    Spinoff.com  https://app.box.com/shared/static/ceeto8oyyxhc2oj3e7w9yyfglfw4rzb1.pdf   2018.7

  3. CO2を資源として活用できる道を切り開く

    ハリマ化成グループ  Harima Quarterly「最前線の分子科学」One hour interview  https://www.harima.co.jp/hq/one_hour_interview/136/index.html  2018.7

  4. 安定アミドを効率よくアミンに変換する触媒 名大グループが開発

    科学新聞社  科学新聞  2017.6

  5. アミド向け触媒開発 アミンやアルコールに効率変換 名大

    日刊工業新聞社  日刊工業新聞  https://www.nikkan.co.jp/articles/view/00430036  2017.5

  6. Conversations with Saito Susumu: Saving the world from plastics

    Scientific Inquirer  https://scientificinquirer.com/2017/07/26/conversations-with-saito-susumu-saving-the-world-from-plastics/  2017.5

  7. 名古屋大学など,安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    日本経済新聞社  日本経済新聞(online)  http://www.nikkei.com/article/DGXLRSP445188_X10C17A5000000/  2017.5

  8. 環境と資源の危機を 「触媒」で乗り超える

    日本科学技術振興機構   JST News 2016  https://www.jst.go.jp/pr/jst-news/pdf/2015/2016_01_p10.pdf#search=%27カルボン酸+斎藤進+JST+News+2016%27  2016.1

  9. カルボン酸を触媒のみでアルコールに変換

    Chem Station  スポットライトリサーチ  https://www.chem-station.com/blog/2015/10/ruthenium.html  2015.10

  10. カルボン酸を効率よくアルコールに変換 名大 複製物少ない触媒開発 炭素循環型社会の実現に貢献期待

    科学新聞社  科学新聞  2015.9

  11. カルボン酸からアルコールへ変換 名大が高性能触媒開発

    日刊工業新聞社  日刊工業新聞  2015.9

  12. CO2からアルコールへ 名大が新触媒 資源化期待

    中日新聞社  中日(朝刊)  2015.8

  13. Krebs cycle metabolites fall into Carbon Feedstock Internet

    Chem-Station  https://www.chem-station.com/blog/2020/12/mmc.html  2020.12

     More details

    Author:Other 

  14. Catalyzing a zero-carbon world by harvesting energy from living cells

    Bioengineer.org  https://bioengineer.org/catalyzing-a-zero-carbon-world-by-harvesting-energy-from-living-cells/  2020.11

  15. Scientists identify new way to turn energy-poor pathway products into biorenewable ones

    AZO life Science  https://www.azolifesciences.com/news/20201116/Scientists-identify-new-way-to-turn-energy-poor-pathway-products-into-biorenewable-ones.aspx  2020.11

  16. Catalyzing a zero-carbon world by harvesting energy from living cells

    ChemEurope.com  ChemEurope.com, News  https://www.chemeurope.com/en/news/1168679/catalyzing-a-zero-carbon-world-by-harvesting-energy-from-living-cells.html?WT.mc_id=ca0066  2020.11

  17. Catalyzing a zero-carbon world by harvesting energy from living cells

    Bionity.com  https://www.bionity.com/en/news/1168679/catalyzing-a-zero-carbon-world-by-harvesting-energy-from-living-cells.html?WT.mc_id=ca0068  2020.11

  18. Breakthrough: Catalyzing a Zero-Carbon World by Harvesting Energy From Living Cells

    SciTechDaily  https://scitechdaily.com/breakthrough-catalyzing-a-zero-carbon-world-by-harvesting-energy-from-living-cells/  2020.11

  19. Catalyzing a zero-carbon world by harvesting energy from living cells

    Phys.org  Phys.org, Chemistry, Materials  https://phys.org/news/2020-11-catalyzing-zero-carbon-world-harvesting-energy.html  2020.11

  20. Catalyzing A Zero-Carbon World By Harvesting Energy From Living Cells

    Science Magazine  ScienMag  https://scienmag.com/catalyzing-a-zero-carbon-world-by-harvesting-energy-from-living-cells/  2020.11

  21. Catalyzing a zero-carbon world by harvesting energy from living cells

    AAAS, USA  EurekAlert!  https://www.eurekalert.org/pub_releases/2020-11/nu-caz111120.php  2020.11

  22. Harvesting Energy From Living Cells To Beat Climate Change

    ScienceBlog  https://scienceblog.com/519545/harvesting-energy-from-living-cells-to-beat-climate-change/  2020.11

  23. Catalyzing a zero-carbon world by harvesting energy from living cells

    ScienceDaily  https://www.sciencedaily.com/releases/2020/11/201112093110.htm  2020.11

  24. Self-Condensation of Primary Amines at Ambient Temperature Internet

    Wiley-VCH  ChemistryViews  2018.11

  25. Nagoya University researchers break down plastic waste

    Bio Fuel Daily  http://www.biofueldaily.com/reports/Nagoya_University_researchers_break_down_plastic_waste_999.html  2017.7

  26. Turning metal catalysis on its head for a sustainable future

    ChemEurope.com  http://www.chemeurope.com/en/news/163908/turning-metal-catalysis-on-its-head-for-a-sustainable-future.html?WT.mc_id=ca0066  2017.6

  27. Nagoya University chemists turn metal catalysis on its head for a sustainable future

    RevoScience  http://revoscience.com/en/nagoya-university-chemists-turn-metal-catalysis-head-sustainable-future/  2017.6

  28. New approach to metal catalysis could maximise the value of biomass

    Bioenergy Insight  http://www.bioenergy-news.com/display_news/12527/new_approach_to_metal_catalysis_could_maximise_the_value_of_biomass/  2017.6

  29. Nagoya University Researchers Transform Metal Catalysis for Sustainable Future

    AZO CLEANTECH  http://www.azocleantech.com/news.aspx?newsID=24155  2017.6

  30. Nagoya University chemists turn metal catalysis on its head for a sustainable future

    SpaceDaily  http://www.spacedaily.com/reports/Nagoya_University_chemists_turn_metal_catalysis_on_its_head_for_a_sustainable_future_999.html  2017.6

  31. Nagoya University chemists turn metal catalysis on its head for a sustainable future _ Nagoya University team used high-valent transition metal catalysts for an unconventional hydrogenation of carboxylic acid groups, common to biomass feedstocks. The high-valent catalysts showed good selectivity under mild conditions.

    Asia Research News  2017.6

  32. Chemists turn metal catalysis on its head for a sustainable future Researchers take a nonintuitive approach to metal catalysis for selective conversion of biomass into high-value chemical products under mild conditions

    ScienceDaily  http://www.sciencedaily.com/releases/2017/06/170627134340.htm  2017.6

  33. Chemists turn metal catalysis on its head for a sustainable future

    Phys.org  http://phys.org/news/2017-06-chemists-metal-catalysis-sustainable-future.html  2017.6

  34. Nagoya University chemists turn metal catalysis on its head for a sustainable future

    AlphaGalileo  http://www.alphagalileo.org/ViewItem.aspx?ItemId=176781&CultureCode=en  2017.6

  35. Chemists turn metal catalysis on its head for a sustainable future

    Nanowerk  http://www.nanowerk.com/news2/green/newsid=47208.php  2017.6

  36. Nagoya University chemists turn metal catalysis on its head for a sustainable future Nagoya University researchers take a nonintuitive approach to metal catalysis for selective conversion of biomass into high-value chemical products under mild conditions

    AAAS、USA  EurekAlert! | AAAS  http://www.eurekalert.org/pub_releases/2017-06/nu-nuc062717.php  2017.6

  37. Chemists spin steel catalysis on the conduct for a tolerable future

    rsoftsolution  http://rsoftsolution.com/blog/chemists-turn-metal-catalysis-on-its-head-for-a-sustainable-future.html  2017.6

  38. CHEMISTS TURN METAL CATALYSIS ON ITS HEAD FOR A SUSTAINABLE FUTURE

    Marketscale Sciences  http://www.marketscale.com/industries/sciences/chemists-turn-metal-catalysis-on-its-head-for-a-sustainable-future/  2017.6

  39. Nagoya University chemists turn metal catalysis on its head for a sustainable future

    Nagoya University  NU Research  http://en.nagoya-u.ac.jp/research/activities/news/2017/06/nagoya-university-chemists-turn-metal-catalysis-on-its-head-for-a-sustainable-future.html  2017.6

  40. バイオマス資源から効率的にアルコール合成する新触媒 名古屋大学

    大学ジャーナルonline  http://univ-journal.jp/14433/  2017.6

  41. 名大、カルホ_ン酸を高選択的にアルコールへ水素化するRe触媒を開発

    Academication  https://academication.ations.jp/articles/1092  2017.6

  42. 名大、カルホ_ン酸を高選択的にアルコールへ水素化するRe触媒を開発

    exciteニュース  http://www.excite.co.jp/News/it_biz/20170616/Cobs_1640193.html  2017.6

  43. カルボン酸をアルコールに変換する革新的な水素化触媒を開発 〜レニウムを用いる計画的なアルコールの合成がもたらす炭素循環型社会に期待〜

    日本の研究.com  http://research-er.jp/articles/view/59420  2017.6

  44. 名大、カルホ_ン酸を高選択的にアルコールへ水素化するRe触媒を開発

    グノシー マイナビニュース  http://gunosy.com/articles/a7zna  2017.6

  45. 名大、カルホ_ン酸を高選択的にアルコールへ水素化するRe触媒を開発

    エネ速  http://energy.1of.biz/hydrogen-energy/56226/  2017.6

  46. 名大、カルボン酸を高選択的にアルコールへ水素化するRe触媒を開発

    Livedoorニュース  https://news.livedoor.com/名大、カルボン酸を高選択的にアルコールへ水素化するRe触媒を開発/article/detail/13211530/  2017.6

  47. 名大、カルホ_ン酸を高選択的にアルコールへ水素化するRe触媒を開発

    Mapionニュース  http://www.mapion.co.jp/news/column/cobs1640193-1-all/  2017.6

  48. カルボン酸をアルコール変換する革新的な水素化触媒を開発 〜レニウムを用いる計画的なアルコールの合成がもたらす炭素循環社会に期待〜

    名古屋大学  名古屋大学プレスリリース  http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20170614_sci_1.pdf  2017.6

  49. カルボン酸をアルコール変換する革新的な水素化触媒を開発 〜レニウムを用いる計画的なアルコールの合成がもたらす炭素循環社会に期待〜

    日本科学技術振興機構  JST プレスリリース  http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20170614_sci_1.pdf  2017.6

  50. Nagoya University Chemists Turn Metal Catalysis On Its Head For A Sustainable Future

    Scienmag  http://scienmag.com/nagoya-university-chemists-turn-metal-catalysis-on-its-head-for-a-sustainable-future/  2017.6

  51. New compound that can break down plastic waste developed

    Daily Excelsior.com  http://www.dailyexcelsior.com/new-compound-that-can-break-down-plastic-waste-developed/  2017.5

  52. Researchers break down plastic waste under mild conditions

    TheeWeek  http://www.theweek.in/content/archival/news/sci-tech/researchers-break-down-plastic-waste-under-mild-conditions.html  2017.5

  53. New compound that can break down plastic waste developed

    India.com  http://www.india.com/news/agencies/new-compound-that-can-break-down-plastic-waste-developed-2180589/  2017.5

  54. New compound that can break down plastic waste developed

    Business Standard, Tokyo  http://www.business-standard.com/article/pti-stories/new-compound-that-can-break-down-plastic-waste-developed-117052900832_1.html  2017.5

  55. 安定アミドを効率よくアミンやアルコールにい変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    日本科学技術振興機構  JST プレスリリース  http://www.jst.go.jp/pr/announce/20170516/index.html  2017.5

  56. 安定アミドを効率よくアミンやアルコールにい変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    名古屋大学   名古屋大学 プレスリリース  http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20170516_sci_1.pdf  2017.5

  57. Nagoya University Researchers Break Down Plastic Waste

    AlphaGalileo  http://www.alphagalileo.org/ViewItem.aspx?ItemId=175757&CultureCode=en  2017.5

  58. Nagoya University Researchers Break Down Plastic Waste

    Nagoya University  NU Research  http://en.nagoya-u.ac.jp/research/activities/news/2017/05/nagoya-university-researchers-break-down-plastic-waste.html  2017.5

  59. Nagoya University Researchers Break Down Plastic Waste

    Science News Line _ Physics & Chemistry   http://www.sciencenewsline.com/news/2017052616460030.html  2017.5

  60. Nagoya University researchers break down plastic waste Nagoya University-based research team develops new highly efficient catalyst for breaking resistant chemical bonds, paving the way for easier recycling of plastic waste

    EurekAlert! |AAAS The Global Source for Science News  http://www.eurekalert.org/pub_releases/2017-05/nu-nur052617.php  2017.5

  61. New catalyst paving the way for easier recycling of plastic waste

    Nanowerk  http://www.nanowerk.com/news2/green/newsid=46841.php  2017.5

  62. Researchers break down plastic waste

    Phys.Org  http://phys.org/news/2017-05-plastic.html  2017.5

  63. Nagoya University researchers break down plastic waste

    Health Medicine Network  http://healthmedicinet.com/i/nagoya-university-researchers-break-down-plastic-waste/  2017.5

  64. Researchers Break down Plastic Waste _ Nagoya University-based research team develops new highly efficient catalyst for breaking resistant chemical bonds, paving the way for easier recycling of plastic waste

    Lab Manager  http://www.labmanager.com/news/2017/05/researchers-break-down-plastic-waste#.WSlTFoQRiSw  2017.5

  65. Nagoya University Researchers Break Down Plastic Waste _ Nagoya University-based research team develops new highly efficient catalyst for breaking resistant chemical bonds, paving the way for easier recycling of plastic waste.

    Asia Research News  http://www.researchsea.com/html/article.php/aid/10754/cid/1/research/science/nagoya_university/nagoya_university_researchers_break_down_plastic_waste.html  2017.5

  66. Nagoya University researchers succeed in breaking down plastic waste in an easier way

    Crazy Engineers  http://www.crazyengineers.com/news/nagoya-university-researchers-succeed-in-breaking-down-plastic-waste-in-an-easier-way.96039/  2017.5

  67. According to the study, organometallic ruthenium catalysts may break down even the toughest amide bonds effectively under mild conditions.

    DNA daily news and analysis (ANI)  http://www.dnaindia.com/technology/report-according-to-the-study-organometallic-ruthenium-catalysts-may-break-down-even-the-toughest-amide-bonds-effectively-under-mild-conditions-2454146  2017.5

  68. Researchers break down under mild conditions

    Financial Express  http://www.financialexpress.com/lifestyle/science/researchers-break-down-under-mild-conditions/690484/  2017.5

  69. Researchers break down plastic waste under mild conditions

    Business Standard, Washington  http://www.business-standard.com/article/news-ani/researchers-break-down-plastic-waste-under-mild-conditions-117052900154_1.html  2017.5

  70. Researchers break down plastic waste under mild conditions

    newkeraka.com  http://www.newkerala.com/news/fullnews-246218.html  2017.5

  71. Researchers break down plastic waste under mild conditions

    Siasat Daily  http://www.siasat.com/news/researchers-break-plastic-waste-mild-conditions-1191044/  2017.5

  72. Japanse onderzoekers hebben organorutheniumkatalysatoren ontwikkeld die amides kunnen afbreken, dus misschien ook nylon. Dat melden ze in Nature.

    C2W  http://www.c2w.nl/nieuws/ruthenium-in-strijd-tegen-de-nylonsoep/item19110  2017.5

  73. Breaking down plastic waste Organoruthenium mediated hydrogenation under mild conditions

    ChemEurope.com  http://www.chemeurope.com/en/news/163424/breaking-down-plastic-waste.html?WT.mc_id=ca0066  2017.5

  74. Newly-developed compound will be able to break down plastic waste! _ Although amide bonds can give great strength to plastics, when it comes to their recycling at a later point, the difficultly of breaking these bonds usually prevents recovery of useful products.

    Zeenews  http://zeenews.india.com/environment/newly-developed-compound-will-be-able-to-break-down-plastic-waste-2010174.html  2017.5

  75. New Highly Efficient Catalyst for Breaking Resistant Chemical Bonds Simplifies Recycling of Plastic Waste

    AzocleanTech  http://www.azocleantech.com/news.aspx?newsID=24089  2017.5

  76. A Mild Way To Break Down Plastic Waste

    AsianScientists  http://www.asianscientist.com/2017/05/in-the-lab/catalyst-plastic-waste-recycling/  2017.5

  77. Hacia un proceso pr_ctico para descomponer pl_stico

    NCYT Noticias de la Clencai y la Technologia  http://noticiasdelaciencia.com/not/24599/hacia-un-proceso-practico-para-descomponer-plastico/  2017.5

  78. 安定アミドを効率よくアミンやアルコールに変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    日本の研究.com  http://research-er.jp/articles/view/58397  2017.5

  79. 安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    J-Net21 中小企業ビジネス支援サイト  http://j-net21.smrj.go.jp/snavi/Contents/0000095783  2017.5

  80. 名古屋大学など、低温/低水素圧で安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    fabcross for エンジニア  http://engineer.fabcross.jp/archeive/170518_nagoya-u.html  2017.5

  81. 名古屋大学、炭素循環社会を実現する安定アミドを効率よくアミンやアルコールに変換する触媒を開発

    炭素ニュース  http://blog.goo.ne.jp/kagaku2012/e/cbeb1f2ef7a47bc1f056763e7bcfb747  2017.5

  82. 天然に豊富なカルボン酸を効率よくアルコールに変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    名古屋大学  名古屋大学 プレスリリース  http://www.nagoya-u.ac.jp/about-nu/public-relations/researchinfo/upload_images/20150828_sci.pdf#search='斎藤進+カルボン酸+名古屋大学'  2015.8

  83. 天然に豊富なカルボン酸を効率よくアルコールに変換する触媒を開発 〜再生可能な資源として炭素循環社会の実現に貢献〜

    日本科学技術振興機構  JST プレスリリース  http://www.jst.go.jp/pr/announce/20150828-2/  2015.8

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