Updated on 2022/04/04

写真a

 
HONDA, Hiroyuki
 
Organization
Graduate School of Engineering Biomolecular Engineering 2 Professor
Graduate School
Graduate School of Engineering
Undergraduate School
School of Engineering Chemistry and Biotechnology
Title
Professor
Contact information
メールアドレス

Degree 1

  1. Doctor of Engineering

Research Interests 5

  1. バイオインフォマティクス

  2. 生物化学工学

  3. 医用工学

  4. Biomolecular Engineering

  5. Peptide engineering

Research Areas 5

  1. Life Science / Biomedical engineering  / Tissue Engineering

  2. Life Science / Biomaterials  / Functional Peptide

  3. Nanotechnology/Materials / Bio chemistry  / Peptide

  4. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering  / Biochemical engineering

  5. Nanotechnology/Materials / Nanobioscience  / Magnetic nanoparticle

Current Research Project and SDGs 5

  1. Screening of functional peptide by peptide array

  2. Design of bioactive peptide by machine-learning method

  3. Screening of bioactive peptide from edible protein

  4. Cell array using magnetic labeling method for cell function analysis

  5. Quality control of bioprocess

Research History 7

  1. 改組に伴い、名古屋大学大学院工学研究科生命分子工学専攻 教授   教授

    2007.4

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    Country:Japan

  2. 名古屋大学予防早期医療創成センター 教授を兼務   教授

    2005.7 - 2007.4

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    Country:Japan

  3. 名古屋大学大学院工学研究科化学・生物工学専攻生物機能工学分野 教授   教授

    2004.4

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    Country:Japan

  4. 大学院重点化に伴い、名古屋大学大学院工学研究科化学・生物工学専攻生物機能工学分野 准教授   准教授

    1996.4

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    Country:Japan

  5. Department of Biotechnology, Nagoya University   Assistant Professor

    1992.10

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    Country:Japan

  6. Department of Biotechnology, Tokyo Institute of Technology   Assistant

    1990.2 - 1992.10

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    Country:Japan

  7. Department of Chemical Engineering, Nagoya University   Assistant

    1988.4 - 1990.2

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    Country:Japan

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Education 3

  1. Nagoya University   Graduate School, Division of Engineering

    1985.4 - 1988.3

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    Country: Japan

  2. Nagoya University   Graduate School of Engineering   Department of Chemical Engineering

    1983.4 - 1985.3

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    Country: Japan

  3. Nagoya University   Faculty of Engineering

    1979.4 - 1983.3

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    Country: Japan

Professional Memberships 11

  1. 化学工学会

  2. 日本生物工学会

  3. 日本バイオインフォマティクス学会

  4. 日本化学会

  5. バイオインダストリー協会

  6. 日本農芸化学会

  7. 日本動物細胞工学会

  8. 日本植物細胞分子生物学会

  9. 日本ハイパーサーミア学会

  10. 日本癌学会

  11. 日本感性工学会

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Awards 12

  1. 第10回生物工学功績賞

    2016.9   公益社団法人 日本生物工学会   短鎖ペプチドの新機能発現に関する研究

    本多裕之

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  2. 化学工学会2013年度優秀論文賞

    2013.5   公益社団法人 化学工学会  

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    Country:Japan

  3. 化学工学会研究賞

    2013.3   公益社団法人 化学工学会  

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    Country:Japan

  4. Outstanding Paper Award of 2009

    2010.3   The Society of Chemical Engineers,Japan  

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    Country:Japan

  5. 生物工学論文賞

    2008.8   日本生物工学会  

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    Country:Japan

  6. Outstanding Paper Award of 2007

    2008.3   The Society of Chemical Engineers,Japan  

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    Country:Japan

  7. 生物工学論文賞

    2004.9   日本生物工学会  

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    Country:Japan

  8. 化学工学会2001年優秀論文賞

    2001   公益社団法人化学工学会  

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    Country:Japan

  9. 日本生物工学会照井賞

    1999   日本生物工学会  

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    Country:Japan

  10. 東海化学工業会学術賞

    1997   東海化学工業会  

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    Country:Japan

  11. 日本生物工学会論文賞

    1996   日本生物工学会  

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    Country:Japan

  12. 化学工学会賞奨励賞

    1994   公益社団法人化学工学会  

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    Country:Japan

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Papers 289

  1. Screening of a novel Free Fatty Acid Receptor 1 (FFAR1) agonist peptide by phage display and machine learning based-amino acid substitution Reviewed

    Keitaro Yoshioka, Haruki Yamashita, Kazunori Shimizu, Sayako Shimomura, Takahiro Shibata, Jun-ichi Miyazaki, Hiroyuki Honda

    Biochemical and Biophysical Research Communications   Vol. 550   page: 177 - 183   2121

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1016/j.bbrc.2021.02.142

  2. In Silico Screening of a Bile Acid Micelle Disruption Peptide for Oral Consumptions from Edible Peptide Database Reviewed

    Kento Imai, Yuri Takeuchi, Kazunori Shimizu, Hiroyuki Honda

    Foods   Vol. 10   page: 2496   2021

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.3390/foods10102496

  3. Selective concentration of antimicrobial peptides to heat-treated porous silica gel using adsorption/desorption

    Hagawa Hitomi, Imai Kento, Gao Ziwei, Taniguchi Masayuki, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 133 ( 2 ) page: 161 - 167   2022.2

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  4. Agonist/Antagonist Activity of Oxytocin Variants Obtained from Free Cyclic Peptide Libraries Generated via Amino Acid Substitution

    Kinoshita Remi, Kozaki Ikko, Shimizu Kazunori, Shibata Takahiro, Ochiai Akihito, Honda Hiroyuki

    ACS OMEGA   Vol. 6 ( 46 ) page: 31244 - 31252   2021.11

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  5. In Silico Screening of a Bile Acid Micelle Disruption Peptide for Oral Consumptions from Edible Peptide Database

    Imai Kento, Takeuchi Yuri, Shimizu Kazunori, Honda Hiroyuki

    FOODS   Vol. 10 ( 10 )   2021.10

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  6. Simple stain-free screening method for pectinolytic microorganisms under alkalophilic conditions

    Ishihara Mai, Kikkawa Masahiro, Shimizu Kazunori, Suzuki Hiroaki, Honda Hiroyuki

    BIOTECHNOLOGY LETTERS   Vol. 43 ( 9 ) page: 1905 - 1911   2021.9

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  7. Machine learning screening of bile acid-binding peptides in a peptide database derived from food proteins

    Imai Kento, Shimizu Kazunori, Honda Hiroyuki

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 16123   2021.8

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  8. Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device

    Yamamoto Kazuki, Yamaoka Nao, Imaizumi Yu, Nagashima Takunori, Furutani Taiki, Ito Takuji, Okada Yohei, Honda Hiroyuki, Shimizu Kazunori

    LAB ON A CHIP   Vol. 21 ( 10 ) page: 1897 - 1907   2021.5

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  9. Screening of a novel free fatty acid receptor 1 (FFAR1) agonist peptide by phage display and machine learning based-amino acid substitution

    Yoshioka Keitaro, Yamashita Haruki, Shimizu Kazunori, Shimomura Sayako, Shibata Takahiro, Miyazaki Jun-ichi, Honda Hiroyuki

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   Vol. 550   page: 177 - 183   2021.4

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  10. Heterologous production of new lasso peptide koreensin based on genome mining

    Fuwa Hiroki, Hemmi Hikaru, Kaweewan Issara, Kozaki Ikko, Honda Hiroyuki, Kodani Shinya

    JOURNAL OF ANTIBIOTICS   Vol. 74 ( 1 ) page: 42 - 50   2021.1

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  11. Increasing the activity of cell adherent cyclic NGR peptides by optimizing the peptide length and amino acid character

    Kozaki Ikko, Suzuki Takehiro, You Sheng-Chao, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF PEPTIDE SCIENCE   Vol. 27 ( 1 ) page: e3287   2021.1

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    Language:Japanese  

    DOI: 10.1002/psc.3287

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  12. Screening of FFAR1 activating peptide by molecular structure analysis Reviewed

    Kagaku Kogaku Ronbunshu   Vol. 47 ( 3 ) page: 64-68   2021

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    Authorship:Last author, Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1252/kakoronbunshu.47.64

  13. Machine learning screening of bile acid-binding peptides in a peptide database derived from food proteins Reviewed

    Kento Imai, Kazunori Shimizu, Hiroyuki Honda

    Scientific Reports   Vol. 11   page: 16123   2021

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1038/s41598-021-95461-1

  14. Simple Stain-free screening method for pectinolytic microorganisms under alkalophilic conditions Reviewed

    Mai Ishihara, Masahiro Kikkawa, Kazunori Shimizu, Hiroaki Suzuki, Hiroyuki Honda

    Biotechnology Letter   Vol. 43 ( 9 ) page: 905 - 1911   2021

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  15. Development of a Human Neuromuscular Tissue-on-a-Chip Model on a 24-Well-Plate-Format Compartmentalized Microfluidic Device Reviewed

    Kazuki Yamamoto, Nao Yamaoka, Yu Imaizumi, Takunori Nagashima, Taiki Furutani, Takuji Ito, Yohei Okada, Hiroyuki Honda, Kazunori Shimizu

    Lab on a Chip   Vol. 21   page: 1897 - 1907   2021

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    Language:English   Publishing type:Research paper (scientific journal)  

  16. Development of a Human Neuromuscular Tissue-on-a-Chip Model on a 24-Well-Plate-Format Compartmentalized Microfluidic Device Reviewed

    Kazuki Yamamoto, Nao Yamaoka, Yu Imaizumi, Takunori Nagashima, Taiki Furutani, Takuji Ito, Yohei Okada, Hiroyuki Honda, Kazunori Shimizu

    Lab on a Chip   Vol. 21   page: 1897 - 1907   2021

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  17. Screening of FFAR1-Activating Peptides by Molecular Structural Analysis

    Yoshioka Keitaro, Yamashita Haruki, Fujitani Masaya, Kato Ryuji, Shimizu Kazunori, Honda Hiroyuki

    KAGAKU KOGAKU RONBUNSHU   Vol. 47 ( 3 ) page: 64 - 68   2021

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  18. Controlling distance, size and concentration of nanoconjugates for optimized LSPR based biosensors

    Chowdhury Ankan Dutta, Nasrin Fahmida, Gangopadhyay Rupali, Ganganboina Akhilesh Babu, Takemura Kenshin, Kozaki Ikko, Honda Hiroyuki, Hara Toshimi, Abe Fuyuki, Park Sungjo, Suzuki Tetsuro, Park Enoch Y.

    BIOSENSORS & BIOELECTRONICS   Vol. 170   page: 112657   2020.12

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  19. Machine Learning-Based Amino Acid Substitution of Short Peptides: Acquisition of Peptides with Enhanced Inhibitory Activities against alpha-Amylase and alpha-Glucosidase

    Yamashita Haruki, Fujitani Masaya, Shimizu Kazunori, Kanie Kei, Kato Ryuji, Honda Hiroyuki

    ACS BIOMATERIALS SCIENCE & ENGINEERING   Vol. 6 ( 11 ) page: 6117 - 6125   2020.11

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  20. Bile acid micelle disruption activity of short-chain peptides from tryptic hydrolyzate of edible proteins

    Ito Masako, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 130 ( 5 ) page: 514 - 519   2020.11

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  21. In Vitro Model of Human Skeletal Muscle Tissues with Contractility Fabricated by Immortalized Human Myogenic Cells

    Nagashima Takunori, Hadiwidjaja Stacy, Ohsumi Saki, Murata Akari, Hisada Takumi, Kato Ryuji, Okada Yohei, Honda Hiroyuki, Shimizu Kazunori

    ADVANCED BIOSYSTEMS   Vol. 4 ( 11 ) page: e2000121   2020.11

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  22. Fluorometric virus detection platform using quantum dots-gold nanocomposites optimizing the linker length variation

    Nasrin Fahmida, Chowdhury Ankan Dutta, Takemura Kenshin, Kozaki Ikko, Honda Hiroyuki, Adegoke Oluwasesan, Park Enoch Y.

    ANALYTICA CHIMICA ACTA   Vol. 1109   page: 148 - 157   2020.5

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  23. Fabrication of contractile skeletal muscle tissues using directly converted myoblasts from human fibroblasts.

    Shimizu K, Ohsumi S, Kishida T, Mazda O, Honda H

    Journal of bioscience and bioengineering   Vol. 129 ( 5 ) page: 632 - 637   2020.5

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    DOI: 10.1016/j.jbiosc.2019.11.013

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  24. Disulfide linked hetero dimeric peptide arrays for screening functional peptides inside cells.

    Kozaki I, Shimizu K, Honda H

    Journal of bioscience and bioengineering   Vol. 129 ( 5 ) page: 613 - 618   2020.5

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    DOI: 10.1016/j.jbiosc.2019.11.012

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  25. Effectiveness of Lifestyle Intervention Using the Internet of Things System for Individuals with Early Type 2 Diabetes Mellitus

    Kato Sawako, Ando Masahiko, Honda Hiroyuki, Yoshida Yasuko, Imaizumi Takahiro, Yamamoto Naoki, Maruyama Shoichi

    INTERNAL MEDICINE   Vol. 59 ( 1 ) page: 45 - 53   2020

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.2169/internalmedicine.3150-19

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  26. Increasing the activity of cell adherent cyclic NGR peptides by optimizing the peptide length and amino acid character Reviewed

    Ikko Kozaki, Takehiro Suzuki, You Sheng-Chao, Kazunori Shimizu, Hiroyuki Hond

    Journal of Peptide Science   Vol. 27 ( 1 ) page: e3287   2020

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1002/psc.3287

  27. Fluorometric virus detection platform using quantum dots-gold nanocomposites optimizing the linker length variation Reviewed

    Fahmida Nasrin, Ankan Dutta Chowdhury, Kenshin Takemura, Ikko Kozaki, Hiroyuki Honda, Oluwasesan Adegoke, Enoch Y. Park

    Analytica Chimica Acta   Vol. 1109   page: 148-157   2020

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    DOI: doi.org/10.1016/j.aca.2020.02.039

  28. Effect of cell-extracellular matrix interaction on myogenic characteristics and artificial skeletal muscle tissue Reviewed

    Ran Ding, Masanobu Horie, Sumire Nagasaka, Saki Ohsumi, Kazunori Shimizu, Hiroyuki Honda, Eiji Nagamori, Hideaki Fujita, Takuo Kawamoto

    Journal of Bioscience and Bioengineering   Vol. 130 ( 1 ) page: 98-105   2020

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    DOI: doi.org/10.1016/j.jbiosc.2020.02.008

  29. Bile acid micelle disruption activity of short-chain peptides from tryptic hydrolysate of edible proteins Reviewed

    Masako Ito, Kazunori Shimizu, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 130 ( 5 ) page: 514-519   2020

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    DOI: doi.org/10.1016/j.jbiosc.2020.07.006

  30. Heterologous production of new lasso peptide koreensin based on genome mining Reviewed

    Haruki Yamashita, Masaya Fujitani, Kazunori Shimizu, Kei Kanie, Ryuji Kato, Hiroyuki Honda

    The Journal of Antibiotics     2020

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1038/s41429-020-00363-5

  31. Increasing the activity of cell adherent cyclic NGR peptides by optimizing the peptide length and amino acid character Reviewed

    Ikko Kozaki, Takehiro Suzuki, You Sheng-Chao, Kazunori Shimizu, Hiroyuki Honda

    Journal of Peptide Science   Vol. 27 ( 1 ) page: e3287   2020

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1002/psc.3287

  32. Machine learning-based amino acid substitution of short peptides: Acquisition of peptides with enhanced inhibitory activities against α-amylase and α-glucosidase Reviewed

    Haruki Yamashita, Masaya Fujitani, Kazunori Shimizu, Kei Kanie, Ryuji Kato, Hiroyuki Honda

    ACS Biomaterials Science & Engineering     2020

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1021/acsbiomaterials.0c01010

  33. Controlling distance, size and concentration of nanoconjugates for optimized LSPR based biosensors Reviewed

    Ankan Dutta Chowdhury, Fahmida Nasrin, Rupali Gangopadhyay, Akhilesh Babu Ganganboina, Kenshin Takemura, Ikko Kozaki, Hiroyuki Honda, Toshimi Hara, Fuyuki Abe, Tetsuro Suzuki, Enoch Y. Park

    Biosensors and Bioelectronics   Vol. 170   page: 112657   2020

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1016/j.bios.2020.112657

  34. In Vitro Model of Human Skeletal Muscle Tissues with Contractility Fabricated by Immortalized Human Myogenic Cells Reviewed

    Kazunori Shimizu, Takunori Nagashima, Stacy Hariwijawa, Saki Ohsumi, Akari Murata, Yohei Okada, Hiroyuki Honda

    Advanced Biosystems     2020

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: doi.org/10.1002/adbi.202000121

  35. Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ Reviewed

    Masayoshi Okada, Ikko Kozaki, Hiroyuki Honda

    PLoS ONE   Vol. 15 ( 11 ) page: e023815   2020

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    DOI: doi.org/10.1371/journal.pone.0233815

  36. Pep-MS assay: Protease hydrolysis assay system using photo-cleavable peptide array and mass spectrometer

    Kurimoto Masaki, Shimizu Kazunori, Ochi Hiroshi, Abe Fumiaki, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 128 ( 2 ) page: 156 - 161   2019.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2019.02.005

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  37. Predictive selection and evaluation of appropriate functional peptides for intestinal delivery with a porous silica gel

    Imai Kento, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 128 ( 1 ) page: 44 - 49   2019.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2019.01.001

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  38. Open-Chamber Co-Culture Microdevices for Single-Cell Analysis of Skeletal Muscle Myotubes and Motor Neurons with Neuromuscular Junctions

    Yamaoka Nao, Shimizu Kazunori, Imaizumi Yu, Ito Takuji, Okada Yohei, Honda Hiroyuki

    BIOCHIP JOURNAL   Vol. 13 ( 2 ) page: 127 - 132   2019.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s13206-018-3202-3

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  39. Identification of an early cell fate regulator by detecting dynamics in transcriptional heterogeneity and co-regulation during astrocyte differentiation

    Ando Tatsuya, Kato Ryuji, Honda Hiroyuki

    NPJ SYSTEMS BIOLOGY AND APPLICATIONS   Vol. 5   page: 18   2019.5

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    DOI: 10.1038/s41540-019-0095-2

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  40. Searching for high-binding peptides to bile acid for inhibition of intestinal cholesterol absorption using principal component analysis.

    Ito M, Shimizu K, Honda H

    Journal of bioscience and bioengineering   Vol. 127 ( 3 ) page: 366 - 371   2019.3

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    DOI: 10.1016/j.jbiosc.2018.08.006

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  41. Selective Elimination of Bitter Peptides by Adsorption to Heat-treated Porous Silica Gel

    Imai Kento, Ikeda Aya, Shimizu Kazunori, Honda Hiroyuki

    FOOD SCIENCE AND TECHNOLOGY RESEARCH   Vol. 25 ( 2 ) page: 179-186   2019.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3136/fstr.25.179

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  42. In-process evaluation of culture errors using morphology-based image analysis

    Imai Yuta, Yoshida Kei, Matsumoto Megumi, Okada Mai, Kanie Kei, Shimizu Kazunori, Honda Hiroyuki, Kato Ryuji

    REGENERATIVE THERAPY   Vol. 9   page: 15-23   2018.12

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    DOI: 10.1016/j.reth.2018.06.001

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  43. Genomic analysis of a Streptomyces tsukubaensis mutant with reduced FR900525 production isolated by selection for S-(2-aminoethyl) L-cysteine resistance

    Shimizu Shiho, Futase Ayako, Yokoyama Tatsuya, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 126 ( 5 ) page: 580-585   2018.11

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    DOI: 10.1016/j.jbiosc.2018.05.009

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  44. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine

    Nagashima Takunori, Shimizu Kazunori, Matsumoto Ryo, Honda Hiroyuki

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 12427   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-018-30936-2

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  45. Interaction between porous silica gel microcarriers and peptides for oral administration of functional peptides

    Imai Kento, Shimizu Kazunori, Kamimura Mitsuhiro, Honda Hiroyuki

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 10971   2018.7

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    DOI: 10.1038/s41598-018-29345-2

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  46. Mutations responsible for alcohol tolerance in the mutant of Synechococcus elongatus PCC 7942 (SY1043) obtained by single-cell screening system.

    Hirokawa Y, Kanesaki Y, Arai S, Saruta F, Hayashihara K, Murakami A, Shimizu K, Honda H, Yoshikawa H, Hanai T

    Journal of bioscience and bioengineering   Vol. 125 ( 5 ) page: 572 - 577   2018.5

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2017.11.012

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  47. Lifestyle intervention using Internet of Things (IoT) for the elderly: A study protocol for a randomized control trial (the BEST-LIFE study)

    Kato Sawako, Ando Masahiko, Kondo Takaaki, Yoshida Yasuko, Honda Hiroyuki, Maruyama Shoichi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 80 ( 2 ) page: 175-182   2018.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.18999/nagjms.80.2.175

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  48. Genomic analysis of a Streptomyces tsukubaensis mutant with reduced FR900525 production isolated by selection for S-(2-aminoethyl) L-cysteine resistance, Reviewed

    Shiho Shimizu, Futase Ayako, Tatsuya Yokoyama, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 126 ( 5 ) page: 580-585   2018.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: org/10.1016/j.jbiosc.2018.05.009

  49. Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits.

    Imaizumi T, Ando M, Nakatochi M, Yasuda Y, Honda H, Kuwatsuka Y, Kato S, Kondo T, Iwata M, Nakashima T, Yasui H, Takamatsu H, Okajima H, Yoshida Y, Maruyama S

    Obesity research & clinical practice   Vol. 12 ( 1S1 ) page: 39-48   2018.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.orcp.2016.05.004

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  50. Effective screening for hypolipidemic bile acid-binding peptides by hierarchical clustering-based catalog array. Journal of Bioscience Reviewed

    Ryuji Kato, Kei Kanie, Chiaki Kaga, Mina Okochi, Satoshi Nagaoka, Hiroyuki Honda

    Biotechnology and Applied Biochemistry   Vol. 1 ( 1 ) page: 1001   2018

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  51. Screening of peptides associated with adhesion and aggregation of Lactobacillus rhamnosus GG in vitro

    Okochi Mina, Sugita Tomoya, Asai Yuji, Tanaka Masayoshi, Honda Hiroyuki

    BIOCHEMICAL ENGINEERING JOURNAL   Vol. 128   page: 178-185   2017.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.bej.2017.10.004

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  52. Association between kidney function and genetic polymorphisms in atherosclerotic and chronic kidney diseases: A cross-sectional study in Japanese male workers

    Kubo Yoko, Imaizumi Takahiro, Ando Masahiko, Nakatochi Masahiro, Yasuda Yoshinari, Honda Hiroyuki, Kuwatsuka Yachiyo, Kato Sawako, Kikuchi Kyoko, Kondo Takaaki, Iwata Masamitsu, Nakashima Toru, Yasui Hiroshi, Takamatsu Hideki, Okajima Hiroshi, Yoshida Yasuko, Maruyama Shoichi

    PLOS ONE   Vol. 12 ( 10 ) page: e0185476   2017.10

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    DOI: 10.1371/journal.pone.0185476

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  53. Morphology-based non-invasive quantitative prediction of the differentiation status of neural stem cells

    Fujitani Masaya, Huddin Noor Safika, Kawai Shun, Kanie Kei, Kiyota Yasujiro, Shimizu Kazunori, Honda Hiroyuki, Kato Ryuji

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 124 ( 3 ) page: 351-358   2017.9

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    DOI: 10.1016/j.jbiosc.2017.04.006

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  54. Randomized controlled trial for assessment of Internet of Things system to guide intensive glucose control in diabetes outpatients: Nagoya Health Navigator Study protocol

    Onoue Takeshi, Goto Motomitsu, Kobayashi Tomoko, Tominaga Takashi, Ando Masahiko, Honda Hiroyuki, Yoshida Yasuko, Tosaki Takahiro, Yokoi Hisashi, Kato Sawako, Maruyama Shoichi, Arima Hiroshi

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 79 ( 3 ) page: 323 - 329   2017.8

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    DOI: 10.18999/nagjms.79.3.323

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  55. Alcohol-tolerant mutants of cyanobacterium Synechococcus elongatus PCC 7942 obtained by single-cell mutant screening system

    Arai Sayuri, Hayashihara Kayoko, Kanamoto Yuki, Shimizu Kazunori, Hirokawa Yasutaka, Hanai Taizo, Murakami Akio, Honda Hiroyuki

    BIOTECHNOLOGY AND BIOENGINEERING   Vol. 114 ( 8 ) page: 1771-1778   2017.8

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    DOI: 10.1002/bit.26307

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  56. Effective modification of cell death-inducing intracellular peptides by means of a photo-cleavable peptide array-based screening system

    Kozaki Ikko, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 124 ( 2 ) page: 209 - 214   2017.8

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    DOI: 10.1016/j.jbiosc.2017.03.013

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  57. Detection of Her2-overexpressing cancer cells using keyhole shaped chamber array employing a magnetic droplet-handling system

    Okochi Mina, Koike Shinji, Tanaka Masayoshi, Honda Hiroyuki

    BIOSENSORS & BIOELECTRONICS   Vol. 93   page: 32-39   2017.7

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    DOI: 10.1016/j.bios.2016.11.013

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  58. Three-Dimensional Culture Model of Skeletal Muscle Tissue with Atrophy Induced by Dexamethasone.

    Shimizu K, Genma R, Gotou Y, Nagasaka S, Honda H

    Bioengineering (Basel, Switzerland)   Vol. 4 ( 2 )   2017.6

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    DOI: 10.3390/bioengineering4020056

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  59. Reduction of FR900525 using an S-(2-aminoethyl) L-cysteine-resistant mutant

    Shimizu Shiho, Futase Ayako, Yokoyama Tatsuya, Ueda Satoshi, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 123 ( 6 ) page: 685-691   2017.6

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    DOI: 10.1016/j.jbiosc.2017.01.006

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  60. Association of interactions between dietary salt consumption and hypertension-susceptibility genetic polymorphisms with blood pressure among Japanese male workers

    Imaizumi Takahiro, Ando Masahiko, Nakatochi Masahiro, Maruyama Shoichi, Yasuda Yoshinari, Honda Hiroyuki, Kuwatsuka Yachiyo, Kato Sawako, Kondo Takaaki, Iwata Masamitsu, Nakashima Toru, Yasui Hiroshi, Takamatsu Hideki, Okajima Hiroshi, Yoshida Yasuko, Matsuo Seiichi

    CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 21 ( 3 ) page: 457-464   2017.6

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    DOI: 10.1007/s10157-016-1315-3

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  61. Visualization of morphological categories of colonies for monitoring of effect on induced pluripotent stem cell culture status

    Nagasaka Risako, Matsumoto Megumi, Okada Mai, Sasaki Hiroto, Kanie Kei, Kii Hiroaki, Uozumi Takayuki, Kiyota Yasujiro, Honda Hiroyuki, Kato Ryuji

    REGENERATIVE THERAPY   Vol. 6   page: 41 - 51   2017.6

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    DOI: 10.1016/j.reth.2016.12.003

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  62. Image-based cell quality evaluation to detect irregularities under same culture process of human induced pluripotent stem cells

    Nagasaka Risako, Gotou Yuto, Yoshida Kei, Kanie Kei, Shimizu Kazunori, Honda Hiroyuki, Kato Ryuji

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 123 ( 5 ) page: 642-650   2017.5

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    DOI: 10.1016/j.jbiosc.2016.12.015

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  63. Comparison of non-destructive evaluation methods for iPS cellular status monitoring

    Nagasaka Risako, Gotou Yuto, Yoshida Kei, Kanie Kei, Shimizu Kazunori, Honda Hiroyuki, Kato Ryuji

    JOURNAL OF PHARMACOLOGICAL SCIENCES   Vol. 133 ( 3 ) page: S247-S247   2017.3

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  64. Exploring high-affinity binding properties of octamer peptides by principal component analysis of tetramer peptides

    Kume Akiko, Kawai Shun, Kato Ryuji, Iwata Shinmei, Shimizu Kazunori, Honda Hiroyuki

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 123 ( 2 ) page: 230-238   2017.2

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    DOI: 10.1016/j.jbiosc.2016.08.005

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  65. [Screening and design of short length functional peptide by peptide array].

    Honda H

    Seikagaku. The Journal of Japanese Biochemical Society   Vol. 89 ( 1 ) page: 15-20   2017.2

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  66. ; Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant Reviewed

    Shiho Shimizu, , Ayako Futase, Tatsuya Yokoyama, Satoshi Ueda, Hiroyuki Honda

    Journal of Bioscience and Bioengineering     2017

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    DOI: 10.1016/j.jbiosc.2017.01.006

  67. Detection of Her2-overexpressing cancer cells using keyhole shaped chamber array employing a magnetic droplet-handling system Reviewed

    Mina Okochi, Shinji Koike, Masayoshi Tanaka, Hiroyuki Honda

    Biosensors and Bioelectronics   Vol. 93   page: 32-39   2017

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  68. Exploring high-affinity binding properties of octamer peptides by principal component analysis of tetramer peptides Reviewed

    Akiko Kume, Shun Kawai, Ryuji Kato, Shinmei Iwata, Kazunori Shimizu, and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 123 ( 2 ) page: 230-238   2017

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    DOI: 10.1016/j.jbiosc.2016.08.005

  69. Image-based cell quality evaluation to detect irregularities under same culture process of human induced pluripotent stem cells Reviewed

    Risako Nagasaka; Yuto Gotou; Kei Yoshida; Kei Kanie, Kazunori Shimizu, Hiroyuki Honda, Ryuji Kato

    Journal of Bioscience and Bioengineering   Vol. 20170000   2017

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    DOI: 10.1016/j.jbiosc.2016.12.015

  70. Morphological Evaluation of Nonlabeled Cells to Detect Stimulation of Nerve Growth Factor Expression by Lyconadin B Reviewed

    Shun Kawai, Hiroto Sasaki, Norihiro Okada, Kei Kanie, Satoshi Yokoshima, Tohru Fukuyama, Hiroyuki Honda, and Ryuji Kato

    J Biomol Screen   Vol. Apr ( 28 )   2016.4

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    DOI: pii: 1087057116645500

  71. Tobias Opthof, Marcel AG van der Heyden, Itsuo Kodama, Jong-Kook Lee: A new in vitro co-culture model using magnetic force-based nanotechnology Reviewed

    Hiroki Takanari, Keiko Miwa, XianMing Fu, Junichi Nakai, Akira Ito, Kousuke Ino, Hiroyuki Honda, Wataru Tonomura, Satoshi Konishi

    Journal of Cellular Physiology   Vol. Feb ( 12 )   2016.2

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    DOI: 10.1002/jcp.25342

  72. Development of a tactical screening method to investigate the characteristics of functional peptides Reviewed

    Akiko Kume, Mina Okochi, Kazunori Shimizu, Yasuko Yoshida, and Hiroyuki Honda

    Biotechnology and Bioprocess Engineering   ( 21 ) page: 119-127   2016

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    DOI: 10.1007/s12257-015-0523-0

  73. A Single Cell Culture System of Cyanobacteria Using Lectin-Conjugated Magnetite Nanoparticles and Magnetic Force Reviewed

    Sayuri Arai, Mina Okochi, Kazunori Shimizu, Taizo Hanai, Hiroyuki Honda

    Biotechnology and Bioengineering   ( 113 ) page: 112-119   2016

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    DOI: 10.1002/bit.25707

  74. Comparisons of cell culture medium using distribution of morphological features in microdevice Reviewed

    Hiroto Sasaki, Junko Enomoto, Yurika Ikeda, Hiroyuki Honda, Junji Fukuda, Ryuji Kato

    Journal of Bioscience and Bioengineering   ( 121 ) page: 117-123   2016

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  75. Rapid colorimetric antibody detection using a dual-function peptide probe for silver nanoparticle aggregation and antibody recognition Reviewed

    Mina Okochi, Tomohiro Kamiya, Takeshi Omasa, Masayoshi Tanaka, Hiroyuki Honda

    Analytical Sciences   ( 32 ) page: 93-97   2016

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  76. Focused screening of ECM-selective adhesion peptides on cellulose-bound peptide microarrays Reviewed

    Kei Kanie, Yuto Kondo, Junk Owaki, Yurika Ikeda, Yuji Narita, Ryuji Kato, Hiroyuki Honda

    Bioengineering   Vol. 3   page: 31   2016

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    DOI: 10.3390/bioengineering3040031

  77. Ex vivo culture of circulating tumor cells using magnetic force-based coculture on a fibroblast feeder layer Reviewed

    Shuhei Yamamoto, Kazunori Shimizu, Jiahui Fei, Hiroji Iwata, Mina Okochi, Hayao Nakanishi and Hiroyuki Honda

    Biotechnology Journal   Vol. 11 ( 11 ) page: 1433-1442   2016

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    DOI: 10.1002/biot.201600084

  78. Parametric analysis of colony morphology of non-labelled live human pluripotent stem cells for cell quality control Reviewed

    Ryuji Kato, Megumi Matsumoto, Hiroto Sasaki, Risako Joto, Mai Okada, Yurika Ikeda, Kei Kanie, Mika Suga, Masaki Kinehara, Kana Yanagihara, Yu-Jung Liu, Kozue Uchio-Yamada, Takayuki Fukuda, Hiroaki Kii, Takayuki Uozumi, Hiroyuki Honda, Yasujiro Kiyota, and Miho Furue

    Scientific Reports   Vol. 6   page: 34009   2016

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    DOI: 10.1038/srep34009

  79. Plasma-Activated Medium Selectively Eliminates Undifferentiated Human Induced Pluripotent Stem Cell

    Ryo Matsumoto, Kazunori Shimizu, Takunori Nagashima, Hiromasa Tanaka, Masaaki Mizuno, Fumitaka Kikkawa, Masaru Hori, Hiroyuki Honda

    Regenerative Therapy   Vol. 5   page: 55-63   2016

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    DOI: org/10.1016/j.reth.2016.07.001

  80. Screening of Osteogenic-Enhancing Short Peptides from BMPs for Biomimetic Material Applications Reviewed

    Kei Kanie, Rio Kurimoto, Jing Tian, Katsumi Ebisawa, Yuji Narita, Hiroyuki Honda and Ryuji Kato

    Materials   Vol. 9   page: 730   2016

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    DOI: 10.3390/ma9090730

  81. Association of interactions between dietary salt consumption and hypertension- susceptibility genetic polymorphisms with blood pressure among Japanese male workers Reviewed

    Takahiro Imaizumi, Masahiko Ando, Masahiro Nakatochi2, Shoichi Maruyama, Yoshinari Yasuda, Hiroyuki Honda, Yachiyo Kuwatsuka, Sawako Kato, Takaaki Kondo, Masamitsu Iwata, Toru Nakashima, Hiroshi Yasui, Hideki Takamatsu, Hiroshi Okajima, Yasuko Yoshida, Seiichi Matsuo

    Clinical and Experimental Nephrology     2016

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    DOI: 10.1007/s10157-016-1315-3

  82. Effect of dietary energy andpolymorphisms in BRAP and GHRL onobesity and metabolic traits Reviewed

    Takahiro Imaizumi, Masahiko Ando, Masahiro Nakatochi, Yoshinari Yasuda, Hiroyuki Honda, Yachiyo Kuwatsuka, Sawako Kato, Takaaki Kondo, Masamitsu Iwata, Toru Nakashima, Hiroshi Yasui,Hideki Takamatsu, Hiroshi Okajima, Yasuko Yoshida,Shoichi Maruyama

    Obesity Research & Clinical Practice     2016

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    DOI: 10.1016/j.orcp.2016.05.004

  83. Effects of the properties of short peptides conjugated with cell-penetrating peptides on their internalization into cells Reviewed

    Ryo Matumoto,Mina Okochi,Kazunori Shimizu,Kei Kanie,Ryuji Kato and Hiroyuki Honda

    SCIENCE REPORTS     2015

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    DOI: 10.1038/srep12884

  84. Three-dimensional magnetic cell array for evaluation of anti-proliferative effects of chemo-thermo treatment on cancer spheroids Reviewed

    Shuhei Yamamoto, Mina Okochi, Kowichi Jimbow, and Hiroyuki Honda

    Biotechnology and Bioprocess Engineering   ( 20 ) page: 488-497   2015

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    DOI: 10.1007/s12257-014-0724-y

  85. Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study Reviewed

    Masahiro Nakatochi, Yasunori Ushida, Yoshinari Yasuda, Yasuko Yoshida, Shun Kawai, Ryuji Kato, Toru Nakashima, Masamitsu Iwata, Yachiyo Kuwatsuka, Masahiko Ando, Nobuyuki Hamajima, Takaaki Kondo, Hiroaki Oda, Mutsuharu Hayashi, Sawako Kato, Makoto Yamaguchi, Shoichi Maruyama, Seiichi Matsuo, and Hiroyuki Honda

    PLOS ONE   ( Feburary 3 )   2015

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    DOI: 10.1371/jornal.phone0117591

  86. Differential variability and correlation of gene expression identifies key genes involved in neuronal differentiation Reviewed

    Tatsuya Ando, Ryuji Kato, Hiroyuki Honda

    BMC Systems Biology   Vol. 9 ( 82 )   2015

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    DOI: 10.1186/s12918-015-0231-6

  87. In vivo heat-stimulus-triggered osteogenesis Reviewed

    Kunihiro Ikuta, Hiroshi Urakawa, Eiji Kozawa, Shunsuke Hamada, Takehiro Ota, Ryuji Kato, Hiroyuki Honda

    International Journal of Hyperthermia   Vol. 31 ( 1 ) page: 58-66   2015

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    DOI: 10.3109/02656736.2014.988662

  88. Design of dual functional peptide probe both as binder to angiotensin II and inducer of silver nanoparticle aggregation for label-free colorimetric assay Reviewed

    Mina Okochi, Masashi Kuboyama, Masayoshi Tanaka and Hiroyuki Honda

    TALANTA   ( 142 ) page: 235-239   2015

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    DOI: 10.1016/j.talanta.2015.04.054

  89. Efficient capturing of circulating tumor cells using a magnetic capture column and a size-selective filter Reviewed

    Shuhei Yamamoto, Jiahui Fei, Mina Okochi, Kazunori Shimizu, Akiko Yusa, Naoto Kondo, Hiroji Iwata, Hayao Nakanishi, and Hiroyuki Honda

    Bioprocess and Biosystems Engineering   ( 38 ) page: 1693-1704   2015

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    DOI: 10.1007/s00449-015-1412-9

  90. Development of a tactical screening method to investigate the characteristics of functional peptides Reviewed

    Tatsuya Ando, Ryuji Kato, Hiroyuki Honda

    BMC Systems Biology   Vol. 9 ( 82 )   2015

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    DOI: 10.1186/s12918-015-0231-6

  91. Characterization of Time-Course Morphological Features for Efficient Prediction of Osteogenic Potential in Human Mesenchymal Stem Cells Reviewed

    Fumiko Matsuoka, Ichiro Takeuchi, Hideki Agata, Hideaki Kagami, Hirofumi Shiono, Yasujiro Kiyota, Hiroyuki Honda, Ryuji Kato

    Biotechnology and Bioengineering     2014

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    DOI: DOI/10.1002/bit.25189

  92. Label-Free Morphology-Based Prediction of Multiple D ifferentiation Potentials of Human Mesenchymal StemCells for Early Evaluation of Intact Cells Reviewed

    Hiroto Sasaki, Ichiro Takeuchi, Mai Okada, Rumi Sawada, Kei Kanie1, Yasujiro Kiyota,Hiroyuki Honda, Ryuji Kato

    PLOS ONE   Vol. 9 ( 4 ) page: e93952   2014

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  93. Degranulation of basophilic leukemia cells on branched-chain peptide array with an ova-dnp double epitope Reviewed

    Hisayuki Sugiura, Noriyasu Okazaki, Toshimi Sugiura, Hiroyuki Honda, Mina Okochi

    Biochemical Engineering Journal   Vol. 87   page: 8–14   2014

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  94. Design of Quenching Peptide Probes Incorporating Tryptophan for Rapid IgG Detection Reviewed

    Tomoya Sugita, Mina Okochi, and Hiroyuki Honda

    Chemistry Letters   Vol. 43 ( 4 ) page: 550–552   2014

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  95. Development of a New Rapid Isolation Device for Circulating Tumor Cells (CTCs) Using 3D Palladium Filter and Its Application for Genetic Analysis

    Akiko Yusa, Makoto Toneri, Taisuke Masuda, Seiji Ito, Shuhei Yamamoto, Mina Okochi, Naoto Kondo, Hiroji Iwata, Yasushi Yatabe, Yoshiyuki Ichinosawa, Seichin Kinuta, Eisaku Kondo, Hiroyuki Honda, Fumihito Arai, Hayao Nakanishi

    PLOS ONE   Vol. 9 ( 2 ) page: e88821   2014

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  96. In vivo heat-stimulus-triggered osteogenesis Reviewed

    Kunihiro Ikuta, Hiroshi Urakawa, Eiji Kozawa, Shunsuke Hamada, Takehiro Ota, Ryuji Kato, Hiroyuki Honda, Takeshi Kobayashi, Naoki Ishiguro, and Yoshihiro Nishida

    International Journal of Hyperthermia   ( Dec 19 ) page: 1-9   2014

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    DOI: 10.3109/02656736.2014.988662

  97. Micro-compartmentalized cultivation of cyanobacteria for mutant screening using glass slides with highly water-repellent mark Reviewed

    Sayuri Arai, Mina Okochi, Taizo Hanai, Hiroyuki Honda

    Biotechnology Reports   Vol. 4   page: 151-155   2014

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  98. Effect of Vascular Formed Endothelial Cell Network on the Invasive Capacity of Melanoma Using the In Vitro 3D Co-Culture Patterning Model Reviewed

    Shuhei Yamamoto, Michael Masakuni Hotta, Mina Okochi, Hiroyuki Honda

    PLOS ONE   Vol. 9 ( 7 ) page: e103502   2014

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  99. Cell Behavior Observation and Gene Expression Analysis of Melanoma Associated with Stromal Fibroblasts in a Three-Dimensional Magnetic Cell Culture Array Reviewed

    Mina Okochi, Taku Matsumura, Shuhei Yamamoto, Eiichi Nakayama, Kowichi Jimbow, Hiroyuki Honda

    Biotechnology Progress   Vol. 29 ( 1 ) page: 135-142   2013

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  100. Comprehensive Combination Analysis for Screening of Significant Peptide Epitopes Using a Slide Glass Type-Exclusive Peptide Array from Milk Protein Reviewed

      Vol. 39 ( 1 ) page: 40-45   2013

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  101. Combinational risk factors of metabolic syndrome from health check-up data identified by Fuzzy neural network Reviewed

    Yasunori Ushida, Ryuji Kato, Kosuke Niwa, Daisuke Tanimura, Hideo Izawa, Kenji Yasui, Tomokazu Takase, Yasuko Yoshida, Mitsuo Kawase, Tsutomu Yoshida, Toyoaki Murohara, Hiroyuki Honda

    BMC Medical Informatics and Decision Making   Vol. 12 ( 80 ) page: doi:10.1186/1472-6947-12-80. 7.   2013

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  102. T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles. Reviewed

    Ito A, Yamaguchi M, Okamoto N, Sanematsu Y, Kawabe Y, Wakamatsu K, Ito S, Honda H, Kobayashi T, Nakayama E, Tamura Y, Okura M, Yamashita T, Jimbow K, Kamihira M

    Nanomedicine   Vol. 8 ( 6 ) page: 891-902   2013

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    DOI: doi: 10.2217/nnm.12.142

  103. Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles

    Kowichi Jimbow, Yasue Ishii-Osai, Shosuke Ito, Yasuaki Tamura, Akira Ito, Akihiro Yoneta, Takafumi Kamiya, Toshiharu Yamashita, Hiroyuki Honda, Kazumasa Wakamatsu, Katsutoshi Murase, Satoshi Nohara, Eiichi Nakayama, Takeo Hasegawa, Itsuo Yamamoto, and Takeshi Kobayashi

    Journal of Skin Cancer     2013

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    DOI: doi.org/10.1155/2013/742925

  104. Droplet-based biochemical assay by magnetic wire manipulation between multiple droplets

    Mitsuhiro Shikida, Tatsuaki Sugito, Mina Okochi, Hiroyuki Honda

    Microsystem Technologies   Vol. 20   page: 315-323   2013

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  105. Morphology-Based Prediction of Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells Reviewed

    Fumiko Matsuoka, Ichiro Takeuchi, Hideki Agata, Hideaki Kagami, Hirofumi Shiono, Yasujiro Kiyota, Hiroyuki Honda, Ryuji Kato

    PLOS ONE   Vol. 8 ( 2 ) page: e55082   2013

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  106. Detection of QT Prolongation Through Approximation of the T Wave on Gaussian Mixture Modeling Reviewed

    Shin Hibino, Norihiro Ueda, Mitsuru Horiba, Kenji Yasui, Yuusuke Kagamihara, Shuji Funahashi, Kaichiro Kamiya, Hiroyuki Honda

    Circulation Journal   Vol. 77   page: 2728-2735   2013

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  107. Macrophage migration inhibitory factor and stearoyl-CoA desaturase 1: Potential prognostic markers for soft tissue sarcomas based on bioinformatics analyses Reviewed

    Hiro Takahashi, Robert Nakayama, Shuhei Hayashi, Takeshi Nemoto, Yasuyuki Murase, Koji Nomura, Teruyoshi Takahashi, Kenji Kubo, Shigetaka Marui, Koji Yasuhara, Tetsuro Nakamura, Takuya Sueo, Anna Takahashi, Kaname Tsutsumiuchi, Tsutomu Ohta, Akira Kawai, Shintaro Sugita, Shinjiro Yamamoto, Takeshi Kobayashi, Hiroyuki Honda, Teruhiko Yoshida, Tadashi Hasegawa

    PLOS ONE   Vol. 8 ( 10 ) page: e78250   2013

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    DOI: doi/10.1371/journal.pone.0078250

  108. Screening of peptide ligands that bind to the Fc region of IgG using peptide array and its application to affinity purification of antibody. Reviewed

    Tomoya Sugita, Makoto Katayama, Mina Okochi, Takamitsu Ichihara, Ryuji Kato, and Hiroyuki Honda

    Biochemical Engineering Journal   Vol. 79   page: 33-40   2013

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  109. Magnetic force-based cell patterning for evaluation of the effect of stromal fibroblasts on invasive capacity in 3D cultures. Reviewed

    Mina Okochi, Taku Matsumura, and Hiroyuki Honda

    Biosensors and Bioelectronics   Vol. 40   page: 300-307   2013

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  110. Morphology-Based Prediction of Osteogenic Differentiation Potential of Human Mesenchymal Stem Cells. Reviewed

    Fumiko Matsuoka, Ichiro Takeuchi, Hideki Agata, Hideaki Kagami, Hirofumi Shiono, Yasujiro Kiyota, Hiroyuki Honda, Ryuji Kato

    PLoS ONE   Vol. 8 ( 2 ) page: e55082   2013

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    DOI: doi/10.1371/journal.pone.0055082

  111. iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis Reviewed

    Tetsutaro Kito, Rei Shibata, Masakazu Ishii, Hirohiko Suzuki, Tatsuhito Himeno, Yoshiyuki Kataoka, Yumiko Yamamura, Takashi Yamamoto, Naomi Nishio, Sachiko Ito, Yasushi Numaguchi, Tohru Tanigawa, Jun K Yamashita, Noriyuki Ouchi, Hiroyuki Honda, Kenichi Isobe and Toyoaki Murohara

    Scientific Reports   Vol. 3   page: 1418   2013

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    DOI: 10.1038/srep01418

  112. Image-Based Cell Quality Assessment: Modeling of Cell Morphology and Quality for Clinical Cell Therapy Reviewed

    Hiroto Sasaki, Fumiko Matsuoka, Wakana Yamamoto, Kenji Kojima, Hiroyuki Honda and Ryuji Kato

    Tissue Engineering and Biomaterials   Vol. 10   page: 207-226   2013

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  113. Mechanism of putative neo-antigen formation from N-propionyl-4-Scysteaminylphenol,a tyrosinase substrate, in melanoma models Reviewed

    Shosuke Ito, Akira Nishigaki, Yasue Ishii-Osai, Makoto Ojika, Kazumasa Wakamatsu,Toshiharu Yamashita, Yasuaki Tamura, Akira Ito, Hiroyuki Honda, Eiichi Nakayama, Kowichi Jimbow

    Biochemical Pharmacology   Vol. 84   page: 646-653   2012

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  114. N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model Reviewed

    Yasue Ishii-Osai, Toshiharu Yamashita, Yasuaki Tamura, Noriyuki Sato, Akira Ito, Hiroyuki Honda, Kazumasa Wakamatsu, Shosuke Ito, Eiichi Nakayama, Masae Okura and Kowichi Jimbow

    Journal of Dermatological Science   Vol. 67   page: 51-60   2012

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  115. Screening for silver nanoparticle-binding peptides by using a peptide array Reviewed

    Masashi Kuboyama, Ryuji Kato, Mina Okochi, Hiroyuki Honda

    Biochemical Engineering Journal   Vol. 66   page: 73– 77   2012

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  116. T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles

    Akira Ito, Masaki Yamaguchi, Noriaki Okamoto, Yuji Sanematsu, Yoshiniri Kawabe, Kazumasa Wakamatsu, Shosuke Ito, Hiroyuki Honda, Takeshi Kobayashi, Eiichi Nakayama, Yasuaki Tamura, Masae Okura, Toshiharu Yamashita, Kowichi Jimbow and Masamichi Kamihira :

    Nanomedicine     2012

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    DOI: 10.2217/NNM.12.142

  117. Enhancement of the Activity of a Lactobacilli- Aggregating Peptide by Freezing Treatment

    Yuji Asai, Tomoya Sugita, Ryuji Kato, Mina Okochi, Kyuya Nakagawa, and Hiroyuki Honda

    Journal of Chemical Engineering   Vol. 48 ( 5 ) page: 609-614   2012

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  118. Collagen type IV-specific tripeptides for selective adhesion of endothelial and smooth muscle cells Reviewed

    Kei Kanie, Yuji Narita, Junki Owaki, Yingzi Zhao, Fumiaki Kuwabara, Makoto Satake, Susumu Honda, Hiroaki Kaneko, Tomohiko Yoshioka, Mina Okochi, Hiroyuki Honda,Ryuji Kato

    Biotechnology and Bioengineering   Vol. 109 ( 7 ) page: 1808-1816   2012

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  119. Screening of an α-Amylase Inhibitor Peptide by photolinker-Peptide Array Reviewed

    Takashi Ochiai, Tomoya Sugita, Ryuji Kato, Mina Okochi, and Hiroyuki Honda

    Bioscience, Biotechnology, and Biochemistry   Vol. 76 ( 4 ) page: 819-824   2012

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  120. Peptide Array-Based Peptide-Cell Interaction Analysis Reviewed

    Ryuji Kato, Chiaki Kaga, Kei Kanie, Mitoshi Kunimatsu, Mina Okochi and Hiroyuki Honda

    Mini-reviews in organic chemistry   Vol. 8 ( 2 ) page: 171-177   2011

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  121. Personalized assessment of oxidative cellular damages associated with diabetes using the erythrocytes adhesion assay Reviewed

    Mina Okochi, Yuki Sakai1 Yayoi Isaji, Hiroshi Nagasaki, Yoji Hamada, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 112 ( 6 ) page: 635-637   2011

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  122. Screening of IgG-Fc binding peptides from milk protein using slide glass type-exclusive peptide array Reviewed

    Makoto KATAYAMA, Tomoya SUGITA, Ryuji KATO, Mina OKOCHI, Miyoko MATSUSHIMA, Tsutomu KAWABE, Tomokazu TAKASE, Yasuko YOSHIDA, Mitsuo KAWASE, Hiroyuki HONDA

    Kagakukougaku Ronbunshu   Vol. 37   page: 546-550   2011

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  123. Fabrication of a pen-shaped portable biochemical reaction system based on magnetic bead manipulatio

    Mituhiro Shikita, Noriyuki Inagaku, Mina Okochi, Hiroyuki Honda, Kazuo Sato

    Journal of Micromechanics and Microengineering   Vol. 21   page: 7   2011

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  124. Droplet introduction into a pen-shaped portable reaction system by gravity and interfacial forces Reviewed

    M. Shikita, N. Inagaki, M. Okochi, H. Honda, K. Sato

    Micro & Nano Letters   Vol. 6 ( 4 ) page: 253-256   2011

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  125. Screening of peptides with a high affinity to bile acids using peptide arrays and a computational analysis

    Toshikazu Takeshita, Mina Okochi, Ryuji Kato, Chiaki Kaga, Yasuyuki Tomita, Satoshi Nagaoka, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 112 ( 1 ) page: 92-97   2011

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  126. mino acid sequence preferences to control cell-specific organization of endothelial cells, smooth muscle cells, and fibroblasts Reviewed

    Kei Kanie, Ryuji Kato, Yingzi Zhao, Yuji Narita, Mina Okochi, Hiroyuki Honda

    Journal of Peptide Science   Vol. 17 ( 6 ) page: 479-486   2011

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  127. Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression Reviewed

    Katsumi Ebisawa, Ryuji Kato, Mai Okada, Tomotaka Sugimura, Mazlyzam Abdul Latif, Yusuke Hori, Yuji Narita, Minoru Ueda, Hiroyuki Honda and Hideaki Kagami

    Journal of Bioscience and Bioengineering   Vol. 111 ( 3 ) page: 255-258   2011

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  128. Peptide Array-Based Peptide-Cell Interaction Analysis Reviewed

    Ryuji Kato, Chiaki Kaga, Kei Kanie, Mitoshi Kunimatsu, Mina Okochi and Hiroyuki Honda

    Mini-reviews in organic chemistry   Vol. 8 ( 2 ) page: 171-177   2011

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  129. Determination of combinational genetic and environmental risk factors of lifestyle-related disease by using health check-up data obtained from long-term follow-up Reviewed

    Yasunori Ushida1, Ryuji Kato1, Daisuke Tanimura2, Hideo Izawa2, Kenji Yasui3,4, Tomokazu Takase5, Yasuko Yoshida, Mitsuo Kawase, Tsutomu Yoshida, Toyoaki Murohara, and Hiroyuki Honda

    Seibutsu-kogaku   Vol. 88 ( 11 ) page: 562-569   2010.4

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  130. Scale-up fermentation of echinocandin-type antibiotic FR901379 Reviewed

    Munekazu Kanda, Eiji Yamamoto, Akihiro Hayashi, Tetsuya Yabutani, Michio Yamashita, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 109 ( 2 ) page: 138-144   2010

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  131. 混合正規分布による心電図T波の近似とQT間隔の自動計測への応用 Reviewed

    日比野 新、中杤昌弘、上田典浩、堀場 充、安井健二、鏡原有祐、寺澤敏昭、神谷香一郎、児玉逸雄、松原充隆、本多裕之

    生体医工学   Vol. 48 ( 4 ) page: 359-368   2010

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  132. Transfer of gene to human retinal pigment epithelial cells using magnetite cationic liposomes Reviewed

    Yasuki Fujii, Shu Kachi, Akira Ito, Tamayo Kawasumi, Hiroyuki Honda, Hiroko Terasaki

    British Journal of Ophthalmology   Vol. 94   page: 1074-1077   2010

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  133. Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release. Reviewed

    Akiko Sato, Yasuaki Tamura, Noriyuki Sato, Toshiharu Yamashita, Tomoaki Takada, Makito Sato,Yasue Osai, Masae Okura, Ichiro Ono, Akira Ito, Hiroyuki Honda, Kazumasa Wakamatsu, Shosuke Ito and Kowichi Jimbow

    Cancer Science   Vol. 110 ( 9 ) page: 1939-1946   2010

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  134. Peptide Array-Based Characterization and Design of ZnO-High Affinity Peptides Reviewed

    Mina Okochi, Tomoya Sugita, Seiji Furusawa, Mitsuo Umetsu, Tadafumi Adschiri, Hiroyuki Honda

    Biotechnology and Bioengineering   Vol. 106 ( 6 ) page: 845-851   2010

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  135. Construction of an Electrochemical Antibiofouling System for Plate Heat Exchangers Reviewed

    Hitoshi Wake, Toshihiro Takimoto, Hirokazu Takayanagi, Kinichi Ozawa, Hideo Kadoi, Shigeki Mukai, Yoshinari Komura, Mina Okochi, Hiroyuki Honda and Tadashi Matsunaga

    Journal of Chemical Engineering of Japan   Vol. 43 ( 7 ) page: 608-611   2010

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  136. Practical cell labeling with magnetite cationic liposomes for cell manipulation Reviewed

    Hiroshi Ito, Yurika Nonogaki, Ryuji Kato, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 110 ( 1 ) page: 124-129   2010

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  137. A compact, automated cell culture system for clinical scale cell expansion from primary tissues Reviewed

    Ryuji Kato, Daisuke Iejima, Hideki Agata, Izumi Asahina, Kunihiko Okada, Minoru Ueda, Hiroyuki Honda, and Hideaki Kagami

    Tissue Engineering Part C     page: Ebub ahead print   2010

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  138. Directed evolution of angiotensin II-inhibiting peptides using a microbead display Reviewed

    Rui Gan, Seiji Furuzawa, Takaaki Kojima, Kei Kanie, Ryuji Kato, Mina Okochi, Hiroyuki Honda, and Hideo Nakano

    Journal of Bioscience and Bioengineering   Vol. 109 ( 4 ) page: 411-417   2010

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  139. Screening of ZnO-high affinity peptide using spot-synthesized peptide arrays and computational analysis Reviewed

    Mina Okochi, Masafumi Ogawa, Chiaki Kaga, Tomoya Sugita, Yasuyuki Tomita, Ryuji Kato, Hiroyuki Honda

    Acta Biomaterialia   Vol. 6   page: 2301-2306   2010

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  140. Fabrication process of carbon nanotube field effect transistors using atomic layer deposition passivation for biosensors. Reviewed

    Yasuhiro Nakashima, Yutaka Ohno, Shigeru Kishimoto, Mina Okochi, Hiroyuki Honda, Takashi Mizutani

    J. Nanosci. Nanotechnol.   Vol. 10   page: 3805-3809   2010

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  141. : Identification of Novel Candidate Genes for Treatment Response to Risperidone and Susceptibility for Schizophrenia: Integrated Analysis Among Pharmacogenomics, Mouse Expression, and Genetic Case-Control Association Approaches Reviewed

    Masashi Ikeda, Yasuyuki Tomita, Akihiro Mouri, Minori Koga, Tomo Ohkouchi, Reiji Yoshimura, Yoshio Yamanouchi, Yoko Kinoshita, Ryota Hashimoto, Hywel Williams, Masatoshi Takeda, Jun Nakamura, Toshitaka Nabeshima, Michael J. Owen, Michael C. O'Donovan, Hiroyuki Honda, Tadao Arinami, Norio Ozaki, Nakao Iwata

    Biological Psychiatry   Vol. 67 ( 3 ) page: 263-269   2010

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  142. Droplet-based gene expression analysis using a device with magnetic force-based-droplet-handling system Reviewed

    Mina Okochi, Hiroyoshi Tsuchiya, Fumitaka Kumazawa, Mitsuhiro Shikida, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 109 ( 2 ) page: 193-197   2010

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  143. Magnetic manipulation device for the optimization of cell processing conditions Reviewed

    Hiroshi Ito, Ryuji Kato, Kousuke Ino, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 109 ( 2 ) page: 182-188   2010

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  144. Approximation of ECG T Wave by Using Gaussian Mixtures and Automatic Measurement of QT Interval Reviewed

    Shin Hibino, Masahiro Nakatochi, Norihiro Ueda, Mitsuru Horiba, Kenji Yasui, Yuusuke Kagamihara, Toshiaki Terazawa, Kaichiro Kamiya, Itsuo Kodama, Michitaka Matsubara, Hiroyuki Honda

    Seitai-Ikougaku   Vol. 48 ( 4 ) page: 359-368   2010

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  145. Forkhead box A1 transcriptional pathway in KRT7-expressing esophageal squamous cell carcinomas with extensive lymph node metastasis s Reviewed

    Masayuki Sano, Kazuhiko Aoyagi, Hiro Takahashi, Takashi Kawamura, Tomoko Mabuchi, Hiroyasu Igaki, Yuji Tachimori, Hoichi Kato, Atsushi Ochiai, Hiroyuki Honda, Yuji Nimura, Masato Nagino, Teruhiko Yoshida, Hiroki Sasak

    International Journal of Oncology   Vol. 36   page: 321-330   2010

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  146. Application of magnetic force-based cell patterning for controlling cell-cell interactions in angiogenesis Reviewed

    Kosuke Ino, Mina Okochi, Hiroyuki Honda :

    Biotechnology and Bioengineering   Vol. 102 ( 3 ) page: 882-890   2009

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  147. Magnetic force-based lab-on-a-chip for single cell analysis in a droplet Reviewed

    Mina Okochi, Hiroyoshi Tsuchiya, Fumitaka Kumazawa, Mitsuhiro Shikida, Hiroyuki Honda

    ECS Transactions   Vol. 16 ( 17 ) page: 15-20   2009

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  148. 部屋の住み心地に及ぼす物理的・感覚的因子の組み合わせ解析-ファジィニューラルネットワークによる住居環境解析-

    牛田泰徳、加藤竜司、守本とも子、本多裕之

    日本感性工学会論文誌   Vol. 9 ( 1 ) page: 97-102   2009

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  149. *Three-dimensional cell culture array using magnetic force-based cell patterning for analysis of invasive capacity of BALB/3T3/v-src Reviewed

    Mina Okochi, Sho Takano, Yayoi Isaji, Takeshi Senga, Michinari Hamaguchi, Hiroyuki Honda

    Lab on a Chip   Vol. 9   page: 3378-3384   2009

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  150. *Peptide array-based analysis of the specific IgE and IgG4 in cow's milk allergens and its use in allergy evaluation Reviewed

    Naoki Matsumoto, Mina Okochi, Miyoko Matsushima, Ryuji Kato, Tomokazu Takase, Yasuko Yoshida, Mitsuo Kawase, Ken-ichi Isobe, Tsutomu Kawabe, Hiroyuki Honda

    Peptides   Vol. 30   page: 1840-1847   2009

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  151. N-Propionyl-Cysteaminylphenol-Magnetite Conjugate (NPrCAP/M) Is a Nanoparticle for the Targeted Growth Suppression of Melanoma Cells Reviewed

    Makito Sato, Toshihar Yamashita, Masae Ohkura, Yasue Osai, Akiko Sato, Tomoaki Takada, Hidenobu Matsusaka, Ichiro Ono, Yasuaki Tamura, Noriyuki Sato, Yasushi Sasaki, Akira Ito, Hiroyuki Hond, Kazumasa Wakamatsu, Shosuke Ito, Kowichi Jimbow

    Journal of Investigative Dermatology   Vol. 129 ( 9 ) page: 2233-2241   2009

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  152. 短鎖機能性ペプチド探索:ペプチドインフォマティクス Invited Reviewed

    本多裕之

    生物工学会誌   Vol. 87 ( 6 ) page: 280-282   2009

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  153. Improvement of FR901379 production by mutant selecton and medium optimization Reviewed

    Munekazu Kanda, Masaru Tsuboi, Kazutoshi Sakamoto, Shiho Shimizu, Michio Yamashita, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 107 ( 5 ) page: 530-534   2009

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  154. Screening of epithelial cell-adhesive peptides from fibronectin loop region and its cell specificity, Reviewed

    Chiaki Kaga, Shigeyuki Nomura, Mina Okochi, Tomoko Nozu, Tomokazu Nagao, Atsushi Nagai, Toshinori Nakayama, Kazuo Suzuki, Hiroyuki Honda

    Journal of Chemical Engineering of Japan   Vol. 42 ( 4 ) page: 298-302   2009

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  155. Preparation of L929 cell array by magnetic pinholder device for single cell function analysis, Reviewed

    Hironobu Koide, Yayoi Isaji, Mina Okochi, Hiroyuki Honda

    Journal of Chemical Engineering of Japan   Vol. 42 ( 4 ) page: 290-297   2009

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  156. Agitation of magnetic beads by multi-layered flat coils Reviewed

    Mitsuhiro Shikida, Motoki Koyama, Nobuhiro Nagao, Rentaro Imai, Hiroyuki Honda, Mina Okochi, Hiroyoshi Tsuchiya, Kazuo Sato

    Sensor and Actuator B: Chemical   Vol. 137   page: 774-780   2009

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  157. 残存脳腫瘍に対する磁気センサを用いた新しい腫瘍検出技術の開発(第一報):マグネタイトカチオニックリポソーム投与の最適化と安全性, Reviewed

    梶田泰一、本多裕之、内山 剛、加藤竜司、林 雄一郎、竹林成典、夏目敦至、水野正明、若林俊彦、吉田 純:

    生体医工学   Vol. 47 ( 1 ) page: 99-104   2009

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  158. Drastic change in cell surface hydrophobicity of a new bacterial strain, Pseudomonas sp. TIS1-127, induced by growth temperature and its effects on the toluene-conversion rate Reviewed

    Katsutoshi Hori, Naoto Hiramatsu, Mari Nannbu, Kei Kanie, Mina Okochi, Hiroyuki Honda, Hisami Watanabe

    Journal of Bioscience and Bioengineering   Vol. 107 ( 3 ) page: 250-255   2009

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  159. Development of peptide arrays for detection of IgE-binding epitopes in cow's milk allergens Reviewed

    Naoki Matsumoto, Mina Okochi, Miyoko Matsushima, Akiko Ogawa, Tomokazu Takase, Yasuko Yoshida, Mitsuo Kawase, Ken-ichi Isobe, Tsutomu Kawabe, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 107 ( 3 ) page: 324-330   2009

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  160. Growth Inhibition of Re-Challenge B16Melanoma Transplant by Conjugates of Melanogenesis Substrate and Magnetite Nanoparticles as the Basis for Developing Melanoma-Targeted Chemo-Thermo-Immunotherapy Reviewed

    Tomoaki Takada, Toshiharu Yamashita, Makito Sato, Aki Tomoaki Takada, Toshiharu Yamashita, Makito Sato, Akiko Sato, Ichiro Ono, Yasuaki Tamura, Noriyuki Sato, Atsushi Miyamoto, Akira Ito, Hiroyuki Honda, KazumasaWakamatsu, Shosuke Ito and Kowichi Jimbow

    Journal of Biomedicine and Biotechnology     2009

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    DOI: 10.1155/2009/457936

  161. Expression Profiling of Peripheral-Blood Mononuclear Cells from Patients with Chronic Hepatitis C Undergoing Interferon Therapy Reviewed

    Makoto Tateno, Masao Honda, Takashi Kawamura, Hiroyuki Honda, and Shuichi Kaneko

    The Journal of Infectious Diseases   Vol. 32 ( 9 ) page: 742-747   2008.4

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  162. The complementarity of the technical tools of tissue engineering and the concepts of artificial organs for the design of functional bioartificial tissues Reviewed

    Petros Lenas1, Angel Moreno, Laertis Ikonomou, Joerg Mayer, Hiroyuki Honda, Antonio Novellino, Camilo Pizarro, Eleni Nicodemou-Lena, Silvia Rodergas, Jesus Pintor

    Artificial Organs   Vol. 32 ( 9 ) page: 742-746   2008.4

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  163. Kamihira : Construction of 3D tissue-like structure using functional magnetite nanoparticles Reviewed

    Akira Ito, Hiroyuki HondaMasamichi

    Yakugaku Zasshi   Vol. 128 ( 1 ) page: 21-28   2008.4

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  164. Hyperthermic treatment of DMBA-induced rat mammary cancer using magnetic nanoparticles Reviewed

    Jun Motoyama, Noriyuki Yamashita, Tomio Morino, Takeshi Kobayashi, Hiroyuki Honda

    BioMagnetic Research and Technology   Vol. 6 ( 2 )   2008

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  165. Effect of global transcriptional regulators related to carbohydrate metabolism on organic solvent tolerance in Escherichia coli Reviewed

    Mina Okochi, Masaki Kurimoto, Kazunori Shimizu, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 105 ( 4 ) page: 389-394   2008

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  166. Fabrication of vertically-aligned carbon nanotube electrodes using grid-inserted plasma-enhanced chemical vapor deposition for chemical sensors Reviewed

    Yoshihiro Kojima, Shigeru Kishimoto, Mina Okochi, Hiroyuki Honda, Takashi Mizutani

    Japanese Journal of Applied Physics   Vol. 47 ( 4 ) page: 2028-2031   2008

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  167. A palmtop-sized rotary-drive-type biochemical analysis system by magnetic bead handling Reviewed

    Mitsuhiro Shikida, Nobuhiro Nagao, Rentaro Imai, Hiroyuki Honda, Mina Okochi, Hiroshi Ito, Kazuo Sato:

    of Micromechanics and Microengineering   Vol. 18 ( 065012(9pp) )   2008

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  168. Cell culture arrays using magnetic force-based cell patterning for dynamic single cell analysis Reviewed

    Kosuke Ino, Mina Okochi, Nao Konishi, Masahiro Nakatochi, Rentaro Imai, Mitsuhiro Shikida, Akira Ito and Hiroyuki Honda

    Lab on a Chip   Vol. 8   page: 134-142   2008

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  169. Size dependent heat generation of magnetite nanoparticles under AC magnetic field for cancer therapy Reviewed

    Jun Motoyama, Toshiyuki Hakata, Ryuji Kato, Noriyuki Yamashita, Tomio Morino, Takeshi Kobayashi, Hiroyuki Honda

    BioMagnetic Research and Technology   Vol. 6   page: 4   2008

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  170. Use of erythrocyte adhesion assay to predict the risk of diabetic complications Reviewed

    Yayoi Isaji, Mina Okochi, Fumihiko Horio, Hiroyuki Honda

    Biochemical Engineering Journal   Vol. 43   page: 178-184   2008

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  171. Cancer DNA microarray analysis considering multi-subclass with graph-based clustering method Reviewed

    Takashi Kawamura, Hironori Mutoh, Yasuyuki Tomita, Ryuji Kato, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 106 ( 5 ) page: 442-448   2008

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  172. 心理・背景因子データからの妊産期うつ病発症リスク診断 Reviewed

    冨田康之、加藤竜司、野坂幸世、武藤裕紀、富田真紀子、濱田祥子、涌井陽子、金井篤子、村瀬聡美、臼井比奈子、石川直子、廣瀬允美、水野妙子、後藤節子、尾崎紀夫、本多裕之

    生物工学会誌   Vol. 86 ( 11 ) page: 519-523   2008

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  173. A motif detection and classification method for peptide sequences using genetic programming Reviewed

    Yasuyuki Tomita, Ryuji Kato, Mina Okochi, and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 106 ( 2 ) page: 154-161   2008

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  174. Peptide array-based screening of human mesenchymal stem cell-adhesive peptides derived from fibronectin type III domain Reviewed

    Mina Okochi, Shigeyuki Nomura, Chiaki Kaga, Hiroyuki Honda

    Biochemical and Biophysical Research Communications   Vol. 371 ( 1 ) page: 85-89   2008

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  175. On-chip polymerase chain reaction microdevice employing a magnetic droplet-manipulation system Reviewed

    Hiroyoshi Tsuchiya, Mina Okochi, Nobuhiro Nagao, Mitsuhiro Shikida and Hiroyuki Honda

    Sensors & Actuators:B. Chemical   Vol. 130 ( 2 ) page: 583-588   2008

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  176. Effect of heat therapy using magnetic nanoparticles conjugated with cationic liposomes on prostate tumor in bone Reviewed

    Noriyasu Kawai, Mituru Futakuchi, Tatsuro Yoshida, Akira Ito, Shinya Sato, Taku Naiki, Hiroyuki Honda :

    Prostate   Vol. 68 ( 7 ) page: 784-792   2008

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  177. Overexpression of prefoldin from the hyperthermophilic archaeum Pyrococcus horikoshii OT3 endowed Escherichia coli with organic solvent tolerance Reviewed

    Mina Okochi, Kei Kanie, Masaki Kurimoto, Masafumi Yohda, Hiroyuki Honda

    Applied Microbiology and Biotechnology   Vol. 79   page: 443-449   2008

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  178. Plasmid DNA transfection Using magnetite cationic liposomes for construction of multilayered gene-engineered cell sheet Reviewed

    Kosuke Ino, Tamayo Kawasumi, Akira Ito, Hiroyuki Honda

    Biotechnology and Bioengineering   Vol. 100 ( 1 ) page: 171-179   2008

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  179. Identification of HLA-A24-restricted epitopes with high affinity to Hsp70 using peptide array Reviewed

    Mina Okochi, Hiroki Hayashi, Akira Ito, Ryuji Kato, Yasuaki Tamura, Noriyuki Sato, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 105 ( 3 ) page: 198-203   2008

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  180. Screening of cell adhesive peptide from the human laminin-5 α3 chain globular 2 and 3 dimains Reviewed

    Shigeyuki Nomura, Chiaki Kaga, Ryuji Kato, Mina Okochi, Hiroyuki Honda:

    Journal of Chemical Engineering of Japan   Vol. 41 ( 3 ) page: 206-209   2008

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  181. Computationally-assisted screening and design of cell-interactive peptides by a cell-based assay using peptide arrays and a fuzzy neural network algorithm Reviewed

    Chiaki Kaga, Mina Okochi, Yasuyuki Tomita, Ryuji Kato, Hiroyuki Honda

    Biotechniques   Vol. 44 ( 3 ) page: 393-402   2008

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  182. Proposal of newly gene filtering method, Bag PART, for gene expression analysis with small samples Reviewed

    Takashi Kawamura, Hiro Takahashi, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 105 ( 1 ) page: 81-84   2008

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  183. Incorporating of capillary-lake structures into dermal cell sheets constructed by magnetic force-bases tissue engineering Reviewed

    kousuke Ino, Akira Ito, Hirohito Kumazawa, Hideaki Kagami, Minoru Ueda, Hiroyuki Honda

    Journal of Chemical Engineering Japan   Vol. 40 ( 1 ) page: 51-58   2007

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  184. Bone tissue engineering with human mesenchymal stem cell sheets constructed using magnetite nanoparticles and magnetic force Reviewed

    Kazunori Shimizu, Akira Ito, Tatsuro Yoshida, Yoichi Yamada, Minoru Ueda, Hiroyuki Honda

    Journal of Biomedical Material Reseach Part B   Vol. 82 ( 2 ) page: 471-480   2007

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  185. Cell patterning using magnetite nanoparticles and magnetic force Reviewed

    Kosuke Ino, Akira Ito, Hiroyuki Honda

    Biotechnology and Bioengineering   Vol. 97 ( 5 ) page: 1309-1317   2007

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  186. Effective cell-seeding using magnetite nanoparticles and magnetic force onto decellularized blood vessels for vascular tissue engineering Reviewed

    Kazunori Shimizu, Akira Ito, Manabu Arinobe, Yosuke Murase, Yoshihisa Iwata, Yuji Narita, Hideaki Kagami, Minoru Ueda, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 103 ( 5 ) page: 472-478   2007

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  187. Association study between apolipoprotein L and schizophrenia by using exhaustive and rule-based analysis method for the identification of multilocus interactions Reviewed

    Yasuyuki Tomita, Masashi Ikeda, Hironori Mutoh, Toshiya Inada, Nakao Iwata, Noriko Ozaki, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 103 ( 4 ) page: 303-310   2007

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  188. Increased organic solvent tolerance by overexpression of manXYZ in Escherichia coli Reviewed

    Mina Okochi, Masaki Kurimoto, Kazunori Simizu, Hiroyuki Honda

    Applied Microbiogy Biotechnology   Vol. 73 ( 6 ) page: 1394-1399   2007

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  189. Construction of multi-layered cardiomyocyte sheets using magnetite nanoparticles and magnetic force Reviewed

    Kazunori Shimizu, Akira Ito, Jong-kook Lee, Tatsuro Yoshida, Keiko Miwa, Hisaaki Ishiguro, Yasushi Numaguchi, Toyoaki Murohara, Itsuo Kodama, Hiroyuki Honda

    Biotechnology and Bioengineering   Vol. 96 ( 4 ) page: 803-809   2007

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  190. Enhanced activity of 3d-hydroxysteroid dehydrogenase by addition of the co-solvent 1-butyl-3-methylimidazolium (L)-lactate in aqueous phase of biphasic systems for reduction of steroids Reviewed

    Mina Okochi, Izumi Nakagawa, Takeshi Kobayashi, Shuhei Hayashi, Shintoro Furusaki, Hiroyuki Honda(2007

    Journal of Biotechnology   Vol. 128   page: 376-382   2007

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  191. 4-S-Cysteaminylphenol-loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma Reviewed

    Akira Ito, Masatake Fujioka, Tatsuro Yoshida, Kazumasa Wakamatsu, Shousuke Ito, Toshiharu Yamashita, Kowichi Jimbow, Hiroyuki Honda

    Cancer Science   Vol. 98 ( 3 ) page: 424-430   2007

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  192. New cancer diagnosis method with exhaustive maker gene selection and reliable prediction modeling using boosting and projective adaptive resonance theory with improved reliable index Reviewed

    Hiro Takahashi, Yasuyuki Murase Takeshi Kobayashi and Hiroyuki Honda

    Biochemical Engineering Journal   Vol. 33   page: 100-109   2007

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  193. Mag-Seeding of Rat Bone Marrow Stromal Cells into Porous Hydroxyapatite Scaffolds for Bone Tissue Engineering Reviewed

    Kazunori Shimizu, Akira Ito and Hiroyuki

    Journal of Bioscience and Bioengineering   Vol. 104 ( 3 ) page: 171-177   2007

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  194. Heat immunotherapy with heat shock protein expression by hyperthermia using magnetite nanoparticles Reviewed

    Akira Ito, Takeshi Kobayashi, Hiroyuki Honda

    Ann.Cancer Res.Therap.   Vol. 15 ( 2 ) page: 27-34   2007

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  195. 異臭味産生藻類のファジイニューラルネットワークによる増殖要因解析 Reviewed

    石橋良信、及川栄作、本多裕之、安達智広、中杤昌弘

    環境工学研究論文集   Vol. 44   page: 255-263   2007

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  196. Application of an ultra-water-repellent surface to cell culture Reviewed

    Kosuke Ino, Akira Ito, Yunying Wu, Nagahiro Saito, Eri Hibino, Osamu Takai, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 104 ( 5 ) page: 420-423   2007

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  197. 爪部悪性黒色腫のための周期的パターン抽出法の開発 Reviewed

    中杤昌弘、古賀 弘、斎田俊明、小林 猛、本多裕之

    化学工学論文集   Vol. 33 ( 6 ) page: 570-580   2007

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  198. Screening of a novel octamer peptide, CNSCWSKD, that induces caspase-dependent cell death Reviewed

    Chiaki Kaga, Mina Okochi, Mari Nakanishi, Hiroki Hayashi, Ryuji Kato, Hiroyuki Honda

    Biochemical and Biophysical Research Communications   Vol. 362 ( 4 ) page: 1063-1068   2007

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  199. Investigation of the relationship between sample size and risk factors for complex diseases based a simulation study Reviewed

    Yasuyuki Tomita, Masahiro Nakatochi, Hiroyuki Asano, Hideo Izawa, Norio Sugimoto, Mitsuhiro Yokota, Hiroyuki Honda

    Chemical-Bioinformatics Journal   Vol. 7 ( 1 ) page: 1-11   2007

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  200. Prediction of peptide binding to major histocompatibility complex class II molecules through use of boosted fussy classfier with SWEEP operator method Reviewed

    Hiro Takahashi and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 101 ( 2 ) page: 137-141   2006

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  201. Proposal of pumpless, valveless, and flowless miniaturized reactor using magnetic beads for a portable gene analysis device Reviewed

    Hiroshi Ito, Kentaro Takayanagi, Mina Okochi, Mitsuhiro Shikida, Kazuo Sato, Hiroyuki Honda

    Journal of Chemical Engineering Japan   Vol. 39 ( 12 ) page: 1296-1299   2006

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  202. Classification method for predicting the development of myocardial infarction by using interaction between genetic and environmental factors Reviewed

    Yasuyuki Tomita, Hiroyuki Asano, Hideo Izawa, Mitsuhiro Yokota and Hiroyuki Honda

    IPSJ Transactions on Bioinformatics   Vol. 47 ( SIG 17(TBIO 1) ) page: 48-66   2006

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  203. Cancer immunotherapy based on intracellular hyperthermia using magnetite nanoparticles: a novel concept of "heat-controlled necrosis" with heat shock protein expression Reviewed

    Akira Ito, Hiroyuki Honda, Takeshi Kobayashi

    Cancer Immunol Immunother   Vol. 55 ( 3 ) page: 320-328   2006

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  204. Development of an enzymatic reaction device using magnetic bead-cluster handling Reviewed

    Mitsuhiro Shikida, Kentaro Takayanagi, Hiroyuki Honda,, Hiroshi Ito, Kazuo Sato

    Journal of Micromechanics and Microengineering   Vol. 16   page: 1875-1883   2006

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  205. Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data using the projective adaptive resonance theory (PART)filtering method Reviewed

    Takeshi Nemoto, Teruhiko Yoshida, Hiroyuki Honda and Tadashi Hasegawa

    BMC Bioinformatics   Vol. 399 ( 7 ) page: 1-11   2006

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  206. Classification of intramural metastases and lymph node metastases for esophageal cancer from gene expression by using boosting and projective adaptive resonance theory Reviewed

    Hiro Takahashi, Kazuhiko Aoyagi, Yukihiro Nakanishi, Hiroki Sasaki, Teruhiko Yoshida, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 102 ( 1 ) page: 46-52   2006

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  207. Lymphoma prognostication from expression profiling using a combination method of boosting and projective adaptive resonance theory Reviewed

    Hiro Takahashi, Hiroyuki Honda

    Journal of Chemical Engineering of Japan   Vol. 39 ( 7 ) page: 767-771   2006

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  208. a new simple and practical gene filtering approach based on the concept of projective adaptive resonance theory (PART) filtering method Reviewed

    Hiro Takahashi, Hiroyuki Honda : Modified signal-to-noise

    Bioinformatics   Vol. 22 ( 13 ) page: 1662-1664   2006

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  209. Fabrication of antigen sensors using carbon nanotubu field effect transistors Reviewed

    Kentaro Tani, Hiroshi Ito, Yutaka Ohno, Shigeru Kishimoto, Mina Okochi, Hiroyuki Honda and Takashi Mizutani

    Japanese Journal of Applied Physics   Vol. 45 ( 6B ) page: 5481-5484   2006

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  210. Peptide array based interaction assay of solid-bound peptide and anchorage-dependant cells and its effectiveness in cell-adhesive peptide design Reviewed

    Ryuji Kato, Chiaki Kaga, Mitoshi Kunimatsu, Takeshi Kobayashi and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 101 ( 6 ) page: 485-495   2006

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  211. Complete regression of experimental prostate cancer in nude mice by repeated hyperthermia using magnetite cationic liposomes and a newly developed solenoid containing a ferrite core Reviewed

    Noriyasu Kawai, Akira Ito, Yoko Nakahara, Hiroyuki Honda, Takeshi Kobayashi, Mitsuru Futakuchi, Tomoyuki Shirai, Keiichi Tozawa, Kenjiro Kohri

    The Prostate   Vol. 66   page: 718-727   2006

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  212. Gene expression property of high density three-dimensional tissue of Hep G2 formed in Radial –flow bioreactor Reviewed

    Tomokatsu Hongo, Mariko Kajikawa, Seiichi Isida, Shougo Ozawa, Yasuo Ono, Junichi Sawada, Youichi Ishikawa, Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 101 ( 3 ) page: 243-250   2006

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  213. Pentamer peptide from Fas antigen ligand inhibits tumor-growth with solid-bound form found by peptide array Reviewed

    Ryuji Kato, Yukako Okuno, Chiaki Kaga, Mitoshi Kunimatsu, Takeshi Kobayashi, and Hiroyuki Honda

    Journal of Peptide Research   Vol. 66   page: 146-153   2006

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  214. Construction of robust prognostic predictors by using projective adaptive resonance theory as a gene filtering method Reviewed

    Hiro Takahashi, Takeshi Kobayashi and Hiroyuki Honda

    Bioinformatics   Vol. 21 ( 2 ) page: 179-186   2005

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  215. High-throughput screening of cell death inducible short peptides from TNF-related apoptosis-inducing ligand sequence Reviewed

    Mina Okochi, Mari Nakanishi, Ryuji Kato, Takeshi Kobayashi, and Hiroyuki Honda

    FEBS Letter   Vol. 580 ( 3 ) page: 885-889   2005

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  216. A new reliable cancer diagnosis method using boosted fuzzy classifier with SWEEP operator method Reviewed

    Hiro Takahashi and Hiroyuki Honda

    Journal of Chemical Engineering of Japan   Vol. 38   page: 763-773   2005

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  217. Exhaustive exploring using artificial neural network for identification of SNPs combination related to helicobacter pylori infection susceptibility Reviewed

    Hironori Mutoh, Nobuyuki Hamajima, Takeshi Kobayashi and Hiroyuki Honda

    Chemical Bio Informatics Journal   Vol. 5 ( 2 ) page: 15-26   2005

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  218. Magnetic force-based mesenchymal stem cell expansion using antibody-conjugated magnetoliposomes Reviewed

    Akira Ito, Eri Hibino, Kazunori Shimizu, Takeshi Kobayashi, Yoichi Yamada, Hideharu Hibi and Minoru Ueda and Hiroyuki Honda

    Journal of Biomedical, Materials Research: Part B-Applied Biomaterials   Vol. 75 ( 2 ) page: 320-327   2005

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  219. Complete regression of hereditary melamona in a mouse model by repeated hyperthermia using magnetite cationic liposomes Reviewed

    Akira Ito, Yoko Nakahara, Masatake Fujioka, Takeshi Kobayashi, Kazue Takeda, Izumi Nakashima and Hiroyuki Honda

    Japanese Journal of Hyperthermic Oncology   Vol. 21 ( 3 ) page: 139-149   2005

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  220. A novel methodology for fabrication of tissue-engineered tubular constructs using magnetite nanoparticles and magnetic force Reviewed

    Akira Ito, Kousuke Ino, Masao Hayashida, Takeshi Kobayashi, Hiroshi Matsumura, Hideaki Kagami, Minoru Ueda and Hiroyuki Honda

    Tissue Engineering   Vol. 11 ( 9/10 ) page: 1553-1561   2005

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  221. Novel strategy for protein exploration High-throughput screening assisted with fuzzy neural network Reviewed

    Ryuji Kato, Hideo Nakano, Hiroyuki Konishi, Katsuya Kato, Yuchi Koga, Tsuneo Yamane, Takeshi Kobayashi and Hiroyuki Honda

    Journal of Molecular Biology   Vol. 351   page: 683-692   2005

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  222. Intratumoral injection of immature cells enhances antitumor effect of hyperthermia using magnetic nanoparticles Reviewed

    Kouji Tanaka, Akira Ito, Takeshi Kobayashi, Tatsuyoshi Kawamura, Shinji Shimada, Kazuhiko Matsumoto, Toshiaki Saida and Hiroyuki Honda

    Int. J of Cancer   Vol. 116   page: 624-633   2005

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  223. Construction and delivery of tissue-engineering human retinal pigment epithelial cell sheets using magnetite nanoparticles and magnetic force Reviewed

    Akira Ito, Eri Hibino, Hiroyuki Honda Chiaki Kobayashi, Hiroko Terasaki, Hideaki Kagami, Minoru Ueda and Takeshi Kobayashi

    Tissue Engineering   Vol. 11 ( 3/4 ) page: 489-496   2005

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  224. Using wettability and interfacial tension to handle droplets of magnetic beads in a micro-chemical-analysis system Reviewed

    Mitsuhiro Shikida, Kentaro Takayanagi, Kohta Inouchi, Hiroyuki Honda and Kazuo Sato

    Sensors and Actuators B   Vol. 113   page: 563-569   2005

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  225. Association between Helicobacter pylori seropositivity and NAD(P)H:quinone oxidoreductase 1(NQO1)C609T polymorphism observed in outpatients and health checkup examinees Reviewed

    Yasuyuki Goto, Nobuyuki Hamajima, Hiroyuki Honda, Keitaro Matsuo, Kazuhito Yamamoto, Akiko Tamakoshi, Takefumi Ando and Hidemi Goto

    Gastric Cancer   Vol. 8   page: 12-17   2005

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  226. The effect of RGD peptide-conjugated magnetite cationic liposomes on cell growth and cell sheet harvesting Reviewed

    Akira Ito, Kousuke Ino, Takeshi Kobayashi and Hiroyuki Honda

    Biomaterials   Vol. 26   page: 6185-6193   2005

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  227. Three-dimensional high density culture of HepG2 cells in a 5-ml radial-flow bioreactor for construction of atificial liver Reviewed

    Tomokatu Hongo, Mariko Kajikawa, Seiichi Ishida, Shogo Ozawa, Yoichi Ishikawa, Takeshi Kobayashi and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 99 ( 3 ) page: 237-244   2005

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  228. Discovery of glpC, an organic solvent tolerance-related gene in Escherichia coli, using gene expression profiles from DNA microarrays Reviewed

    Kazunori Shimizu, Shuhei Hayashi, Takeshi Kako, Maiko Suzuki, Norihiko Tsukagoshi, Noriyuki Doukyu, Takeshi Kobayashi and Hiroyuki Honda

    Applied and Environmental Microbiology   Vol. 71 ( 2 ) page: 1093-1096   2005

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  229. Time-course data analysis of gene expression profiles reveals purR regulon concerns in organic solvent tolerance in Escherichia coli Reviewed

    Kazunori Shimizu, Shuhei Hayashi, Noriyuki Doukyu, Takeshi Kobayashi, and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 99 ( 1 ) page: 72-74   2005

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  230. Antitumor effect of combined therapy of recombinant heat shock protein 70 and hyperthermia using magnetic nanoparticles in an experimental subcutaneous murine melanoma

    Akira Ito,Fumiko Matsuoka,Hiroyuki Honda and Takeshi Kobayashi

    Cancer Immunology and Immunotherapy   Vol. 53   page: 26-32   2004

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  231. A preprocessing method for inferring genetic interaction from gene expression data using Boolian algorithm Reviewed

    Kazumi Hakamada, Taizo Hanai, Hiroyuki Honda and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 98 ( 6 ) page: 457-468   2004

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  232. Prognostic predictor with multiple fuzzy neural models using expression profiles for metastases of breast cancer Reviewed

    Hiro Takahashi, Kayoko Masuda, Tatsuya Ando, Takeshi Kobayashi, and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 98 ( 3 ) page: 193-199   2004

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  233. Local hyperthermia enhances thromobosis in aneurysms containing platinum colis Reviewed

    Osamu Suzuki, Shigeru Miyachi, Takeshi Okamoto, Akira Ito, Masashige Shinkai, Hiroyuki Honda, Takeshi Kobayashi, Makoto Neguro and Jun Yoshida

    Interventional Neuroradiology   Vol. 10 ( 3 ) page: 203-211   2004

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  234. Artificial neural network approach for selection of casual single nucleotide polymorphisms and construction of prediction model on childhood allegic asthma

    Yasuyuki Tomita,Shuta Tomita,Yuko Hasegawa,Yoichi Suzuki,Taro Shirakawa,Takeshi Kobayashi and Hiroyuki Honda

    BMC Bioinformatics   Vol. 5   page: 120   2004

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  235. Tissue engineering using magnetite nanoparticles and magnetic force:heterotypic layers co-cultured hepatocytes and endothelial cells

    Akira Ito,Yohei Kuga,Hiroyuki Honda,Ken-ichiro Hata,Hideaki Kagami,Minoru Ueda and Takeshi Kobayashi

    Tissue Engineering   Vol. 10 ( 5/6 ) page: 833-840   2004

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  236. A new methodology of mesenchymal stem cell expansion using magnetic nanoparticles

    Akira Ito,Eri Hibino,Hiroyuki Honda,Ken-ichiro Hata,Hideaki Kagami,Minoru Ueda and Takeshi Kobayashi

    Biochemical Engineering Journal   Vol. 20   page: 119-125   2004

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  237. Angiotensin Ⅱinhibitory peptide found in the receptor sequence using peptide array

    Ryuji Kato,Mitoshi Kunimatsu,Seigo Fujimoto,Takeshi Kobayashi and Hiroyuki Honda

    Biochemical and Biophysical research Communications   Vol. 315   page: 22-29   2004

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  238. Proposal of reliability index in search for reliable solutions of reversible calculation based on fuzzy neural network modeling Reviewed

    Taizo Hanai, Naoya Iwata, Takeshi Furuhashi, Hiroyuki Honda and Takeshi Kobayashi

    Journal of Chemical Engineering of Japan   Vol. 37 ( 4 ) page: 523-530   2004

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  239. Hyperthermia using magnetite cationic liposomes for hamster osteosarcoma Reviewed

    Fumiko Matsuoka, Masashige Shinkai, Hiroyuki Honda, Tadahiko Kubo, Takashi Sugita and Takeshi Kobayashi

    BioMagnetic Research and Technology   Vol. 2   page: 3   2004

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  240. Magnetite nanoparticle-loaded anti-HER2 immunoliposomes for combination of antibody therapy with hyperthermia Reviewed

    Akira Ito, Yuko Kuga, Hiroyuki Honda, Hiroyuki Kikkawa, Atsushi Horiuchi, Yuji Watanabe and Takeshi Kobayashi

    Cancer Letters   Vol. 212   page: 167-175   2004

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  241. Construction and harvest of multilayered keratinocyte sheets using magnetite nanoparticles and magnetic force Reviewed

    Akira Ito, Masao Hayashida, Hiroyuki Honda, Ken-ichiro Hata, Hideaki Kagami, Minoru Ueda and Takeshi Kobayashi

    Tissue Engineering   Vol. 10 ( 5/6 ) page: 873-880   2004

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  242. Evaluation of the Alzheimer type-dementia by magnetic resonance imaging using fuzzy neural networks Reviewed

    Xicheng Liu, Shin Hibino, Yoshihiro Hasegawa, Taizo Hanai, Takeo Mitsushima, Akihiko Iida, Michitaka Matsubara Hiroyuki Honda and Takeshi Kobayashi

    Journal of Chemical Engineering of Japan   Vol. 37 ( 3 ) page: 429-435   2004

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  243. Analysis of organic solvent tolerance in Escherichia coli using gene expression profiles from DNA microarrays

    Shuhei Hayashi,Rikizo Aono,Taizo Hanai,Hirotada Mori,Takeshi Kobayashi and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 95 ( 4 ) page: 379-383   2003

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  244. Anti-cancer effect and immune inductionbyhyperthermia of malignant melanoma using magnetite cationic liposomes

    Masataka Suzuki,Masashige Shinkai,Hiroyuki Honda,and Takeshi Kobayashi

    Melanoma Reserch   Vol. 13 ( 2 ) page: 129-135   2003

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  245. Transglutaminase-mediated gelatin matrices incorporating cell adhesion factors as a biomaterial for tissue engineering

    Akira Ito,Atunori Mase,Masashige Shinkai,Hiroyuki Honda,Ken-ichoro Hata,Minoru Ueda and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 95 ( 2 ) page: 196-199   2003

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  246. Proliferation and stratification of keratinocite on cultured amniotic cells for tissue Engineering

    Akira Ito,Yohei Takizawa,Masashige Shinkai,Hiroyuki Honda,Ken-ichiro Hata,Minoru Ueda,Naohiko Kuno,Atsuo Itakura and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 95 ( 6 ) page: 589-593   2003

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  247. Complete regression of mouse mammary carcinoma with a size greater than 15mm by frequent repeated hyperthermia using magnetite nanoparticles

    Akira Ito,Kouji Tanaka,Hiroyuki Honda,Shigeru Abe,Hideyo Yamaguchi and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 96 ( 4 ) page: 364-369   2003

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  248. Maltiple fuzzy neural network system for outcome prediction and classification of 220 lymphoma patients on the basis of molecular profiling

    Tatsuya Ando,Miyuki Suguro,Takeshi Kobayashi,Masao Seto and Hiroyuki Honda

    Cancer Science   Vol. 94 ( 10 ) page: 906-913   2003

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  249. Heat shock protein 70 expression induces antitumor immunity during intracellular hyperthermia using magnetic nanoparticles

    Akira Ito,Masashige Shinkai,Hiroyuki Honda,Kazuhiro Yoshikawa,Shinsuke Saga,Toshihiko Wakabayashi,Jun Yoshida and Takeshi Kobayashi

    Cancer Immunology and Immunotherapy   Vol. 52 ( 5 ) page: 80-88   2003

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  250. Screening of stress enhancer based on analysis of gene expression profiles:hyperthermia-induced tumor necrosis by an MMP-3 inhibitor

    Naoko Kato,Takeshi Kobayashi and Hiroyuki Honda

    Cancer Science   Vol. 94 ( 7 ) page: 644-649   2003

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  251. Magnetite needle as heating mediator for intracellular hyperthermia of tumor

    Masashige Shinkai,Kengo Ueno,Hiroyuki Honda and Takeshi Kobayashi

    Japanese Journal of Hyperthermia Oncology   Vol. 18 ( 4 ) page: 191-198   2002

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  252. Hidden Markov model-based prediction of antigenic peptides that interact with MHC class II molecules

    Hideki Noguchi,Ryuji Kato,Taizo Hanai,Yukari Matubara,Hiroyuki Honda,Vladimir Brusic and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 94 ( 3 ) page: 264-270   2002

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  253. Artificial neural network predictive model for allergic disease using single nucleotide polymorphisms data

    Shuta Tomida,Taizo Hanai,Naoki Koma,Youichi Suzuki,Takeshi Kobayashi and Honda Hiroyuki

    Journal of Bioscience and Bioengineering   Vol. 93 ( 5 ) page: 470-478   2002

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  254. Determination of blending ratio on regular coffee samples by information technology

    Osamu Tominaga,Fumio Ito,Taizo Hanai,Hiroyuki Honda and Takeshi kobayashi

    Jornal of Chemical Engineering of Japan   Vol. 35 ( 2 ) page: 137-143   2002

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  255. Effect of functional magnetic particles on radiofrequency capactive hesting

    Masashige Shinkai,Kousuke Ueda,Shinji Ohtsu,Hiroyuki Honda,KenjiroKohri and Takeshi Kobayashi

    Japanese Journal of Cancer Reserch   Vol. 93   page: 103-108   2002

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  256. Magnetite needle as heating mediator for intracellular hyperthermia of tumor Reviewed

    Masashige Shinkai, Kengo Ueno, Hiroyuki Honda and Takeshi Kobayashi

    Japanese Journal of Hyperthermia Oncology   Vol. 18 ( 4 ) page: 191-198   2002

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  257. Fuzzy Neural Network Applied to Gene Expression Profiling for Prognosis of Diffuse Large B-cell Lymphoma Reviewed

    Tatsuya Ando, Miyuki Suguro, Taizo Hanai, Takeshi Kobayashi, Hiroyuki Honda and Masao Seto

    Japanese Journal of Cancer Research93, 1207-1212 (2002)   Vol. 93   page: 1207-1212   2002

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  258. Modeling of consumer's preferences for regular coffee samples and its application to product design Reviewed

    Osamu Tominaga, Fumio Ito, Taizo Hanai, Hiroyuki Honda and Takeshi Kobayashi

    Food Science and Technology Research   Vol. 8 ( 3 ) page: 281-285   2002

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  259. Enhanced anthocyanin production from grape callus in an air-lift type bioreactor using a viscous additive-supplemented medium Reviewed

    Hiroyuki Honda, Kousuke Hiraoka, Eiji Nagamori, Mariko Omote, Yoshihito Kato, Setsuro Hiroka and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 94 ( 2 ) page: 135-139   2002

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  260. Analysis of expression profile using fuzzy adaptive resonance theory Reviewed

    Shuta Tomida, Taizo Hanai, Hiroyuki Honda and Takeshi Kobayashi

    Bioinformatics   Vol. 18 ( 8 ) page: 1073-1083   2002

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  261. Production of single chain recombinant monellin by high cell density culture of genetically engineered Candida utilis using limited feeding of sodium ions Reviewed

    Xiaoli Zhang, Takeshi Ito, Keiji Kondo, Takeshi Kobayashi and Hiroyuki Honda

    Journal of Chemical Engineering of japan   Vol. 35 ( 7 ) page: 654-659   2002

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  262. Artificial neural network predictive model for allergic disease using single nucleotide polymorphisms data Reviewed

    Shuta Tomida,Taizo Hanai,Naoki Koma,Youichi Suzuki, Takeshi Kobayashi and Hiroyuki Honda

    Journal of Bioscience and Bioengineering   Vol. 93 ( 5 ) page: 470-478   2002

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  263. 茶葉ポリフェノール物質による貝類の海藻摂食活性の阻害 Reviewed

    長森英二、服部直人、本多裕之、小林 猛

    化学工学論文集   Vol. 28 ( 3 ) page: 287-291   2002

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  264. Sensory modeling of coffee with a fuzzy neural network Reviewed

    Osamu Tominaga, Fumio Ito, Taizo Hanai, Hiroyuki Honda and Takeshi Kobayashi

    Journal of Food Science   Vol. 67 ( 1 ) page: 363-368   2002

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  265. High celldensity culture of Rhodococcus erythropolis KA2-5-1 for in situ induction of dibenzothiophene degrading activity Reviewed

    Hibiki Matsushita, Takahiro Sugiyama, Hiroyuki Honda and Takeshi Kobayashi

    Journal of the Chinese Institute of Chemical Engineers   Vol. 32 ( 3 ) page: 219-225   2001

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    To obtain cells with high dibenzothiophene (DBT) degrading activity, two phase fed-batch culture of Rhodococcus erythropolis KA 2-5-1 was carried out, which consisted of growth phase in the medium containing sulfate ion as a sulfur source and induction phase for expression of DBT degrading enzyme by DBT addition. Cell concentration of 24.3 g-dry cells/L was obtained after 30 h culture and the maximum specific degrading activity of 18.2 mmol/kg-dry cells/h was achieved at 10 h after induction. In order to simplify the system and lower an operational cost, next, in situ induction of the enzyme activity was conducted by means of sulfur limitation since the activity of the strain can only be induced under sulfur starvation. The strain was cultivated in fed-batch mode in the modified A medium containing 96 mg/L of sulfate ion. At 22 h, sulfate concentration decreased below 10 mg/L and approximately 10 g/L of cell concentration was obtained. When 125 mg/L of DBT was added at 22 h, the enzyme activity increased rapidly and the maximum specific activity of 14.3 mmol/kg-dry cells/h was obtained at 28 h. However, the DBT degrading activity decreased rapidly thereafter. From the assay of remaining concentration of medium components in the culture broth, it was found that Fe and Mg ions were exhausted at the end of cultivation. Fed-batch culture with feeding of concentrated solution of Fe and Mg ions was then conducted. After 23 h, 125 mg/L of DBT was added, and the enzyme activity increased rapidly. In this case, the activity did not decrease, and the maximum specific degrading activity of 18.5 mmol/kg-dry cells/h and cell concentration of 41.7 g-dry cells/L were obtained at 34 h.

  266. Optimization of bovine cathepsin C production by cultivation of recombinant methylotrophic yeast Candida oidinii

    Hiroyuki Kikuta, Kenjiro Kano, Hiroyuki Honda and Takeshi Kobayashi

    Jornal of hemical Engineering of Japan   Vol. 34 ( 6 ) page: 848-851   2001

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  267. Augmentation of MHC class I antigen presentation via heat shock protein expression by hyperthermia Reviewed

    Akira Ito, Masashige Shinkai, Hiroyuki Honda, Toshihiko Wakabayashi, Jun Yoshida and Takeshi Kobayashi

    Cancer Immmunology and Immunotherapy   Vol. 50   page: 515-522   2001

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  268. Fuzzy neural network-based prediction of the motif for MHC class II binding peptides Reviewed

    Hideki Noguchi, Taizo Hanai, Hiroyuki Honda, Leonard C. Harrison and Takeshi Kobayashi

    Journal of Biosience and Bioengineering   Vol. 92 ( 3 ) page: 227-231   2001

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  269. Determination of operating conditions in activated sludge process using fuzzy neural network and genetic algorithm Reviewed

    Hiroyuki Yoshikawa, Taizo Hanai, Shuta Tomida, Hiroyuki Honda, and Takeshi Kobayashi

    Journal of Chemical Engineering of Japan   Vol. 34 ( 8 ) page: 1033-1039   2001

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  270. Fussy neural network model for assessment of Alzheimer-type dementia Reviewed

    Shin Hibino, Taizo Hanai, Erika Nagata, Michitaka Matsubara, Kazutoshi Fukagawa, Tatsuaki Shirataki, Hiroyuki Honda, and Takeshi Kobayashi

    Journal of Chemical Engineering of Japan   Vol. 34 ( 7 ) page: 936-942   2001

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  271. Enhanced and prolonged production of regenerated plantlet from carrot callus in viscous additive-supplemented medium Reviewed

    Eiji Nagamori, Mariko Omote, Hiroyuki Honda and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 91 ( 3 ) page: 283-287   2001

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    To reduce the hydrodynamic stress in plant cell culture and enhance the production of regenerated plantlets, a liquid medium containing a viscous additive was newly designed and plantlet production from embryogenic carrot callus cultivated in the medium was examined. Na-Alginate or carboxymethyl cellulose (CMC) was used as the viscous additive. The viscosity of the medium increased with increasing additive content and the number of regenerated plantlets also increased. When carrot calli were cultivated in the medium containing 0.4% CMC, designated as N medium (viscosity, 3 mPa・s), the maximum enhancement of plantlet regeneration, approximately 2.5 times higher than that in the control medium, was obtained. Enlargement of callus size observed in N medium is considered to be the main reason for the enhanced plantlet regeneration. Regeneration enhancement was sufficiently induced after calli were cultivated once in N medium, but this regenerarion ability rapidly disappeared after once cultivation in the conventional medium. In repeated batch culture using N medium, plantlet production continued at a high level for 18 batches (250 d) with no significant decrease, while in the control culture without CMC the number of plantlets produced dropped to almost zero by the sixth batch (84 d).

  272. Lipase production in two step fed-batch culture of an organic solvent-tolerant Pseudomonas aeruginosa LST-03 Reviewed

    Takeshi Ito, Hirokazu Kikuta, Eiji Nagamori, Hiroyuki Honda, Hiroyasu Ogino, Haruo Ishikawa and Takeshi Kobayashi

    Journal of Bioscience and Bioengineering   Vol. 91 ( 3 ) page: 245-250   2001

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    Efficient lipase production by two-step fed-batch culture of an organic solvent-tolerant bacterium, Pseudomonas aeruginosa LST-03, was investigated. When FB synthetic medium was used in flask culture, no lipase activity was detected, whereas lipase was produced at 2.3 I.U./ml in C2 complex medium. However, lipase production was induced in FB medium when a fatty acid was added to the culture broth in the stationary phase. Among fatty acids tested, long chain saturated fatty acids, such as C18 (stearic acid) and C20 (arachidic acid), were found to function as effective inducers for the production of lipase, giving an activity level almost the same as that obtained in C2 medium in flask culture. Two-step lipase production, comprised of a growth phase in fed-batch mode and a production phase in which lipase was induced by the addition of 5 %(v/v) stearic acid, was carried out in a jar-fermentor. In the growth phase, the maximum cell concentration at 16 h was only 20 in terms of the optical density at 660nm (OD660), and a low level of lipase production (8 I.U./ml) was obtained after 167 h. This was considered to be due to the exhaustion of several medium components brought about by the use of an unsuitable medium or feeding solution. After analyzing the contents of the compounds in the culture broth by inductively coupled plasma spectrometry for metal ions and HPLC for anions, a modified FB medium was designed. When this modified FB medium was used in two-step fed-batch culture, the maximum cell concentration reached an OD660 of 55 (30.2 g-dry cells/l) at 16.5 h, and lipase was produced at 96 I.U./ml after 35 h, which is approximately 40 times higher than the production level obtained in flask culture using C2 medium.

  273. 知的推論モデルによる品質の定量化と培養プロセスの管理

    本多裕之

    生物工学会誌   Vol. 78 ( 3 ) page: 94-100   2000

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  274. Development of chitosan-magnetite aggregates containing Nitrosomonas europaea cells for nitrification enhancement

    Journal of Bioscience and Bioengineering   Vol. 89 ( 5 ) page: 420-425   2000

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  275. Fuzzy control of bioprocess in Japan

    Biotechnology Annual Review   Vol. 5   page: 1-23   2000

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  276. Selection of embryogenic sugarcane callus by image analysis

    Journal of Bioscience and Bioengineering   Vol. 87 ( 5 ) page: 700-702   1999

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  277. Model construction for quality of beer and brewing process using FNN

    Kagaku Kogaku Ronbunshu   Vol. 25 ( 5 ) page: 695-701   1999

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  278. Recovery of recombinant Escherichia coli by chitosan-conjugated magnetite

    Biochemical Engineering Journal   Vol. 3   page: 157-160   1999

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  279. Development of novel magnetic sensing for brain lesion using functional magnetic particles Reviewed

    Masashige Shinkai, Akira Ohshima, Mitsugu Yanase, Tsuyoshi Uchiyama, Kaneo Mohri, Toshihiko Wakabayashi, Jun Yoshida, Hiroyuki Honda and Takeshi Kobayashi

    Kagaku Kougaku Ronbunshu   Vol. 24 ( 2 ) page: 174-178   1998

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  280. Temperature control of Ginjo sake mashing process by automatic fuzzy modeling using fuzzy networks Reviewed

    Hiroyuki Honda, Taizo Hanai, Akemi Katayama, Hisao Tohyama and Takeshi Kobayashi

    Journal of Fermentation and Bioengineering   Vol. 85 ( 1 ) page: 107-112   1998

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  281. High cell density culture of Rhodococcus rhodochrous by pH-stat feeding and dibenzothiophene degradation Reviewed

    Hiroyuki Honda, Hiroyasu Sugiyama, Ikuo Saito and Takeshi Kobayashi

    Journal of Fermentation and Bioengineering   Vol. 85 ( 3 ) page: 334-338   1998

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  282. Colominic acid production from Escherichia coli in a fed-batch culture under the control of ammonium ions using an FIA system

    Journal of Fermentation and Bioengineering.   Vol. 83 ( 1 ) page: 59-63   1997

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  283. Production of Fv fragment of monoclonal antibody from recombinant methylotrophic yeast, Pichia pastoris

    Journal of Chemical Engineering of Japan   Vol. 29 ( 2 ) page: 390-392   1996

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  284. Characteristics on heat sterilization of a novel autoclave with a turntable for rotation

    Journal of Fermentation and Bioengineering   Vol. 81 ( 6 ) page: 570-572   1996

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  285. Effective tPA production by BHK cells in nutrients-controlled culture using on-line HPLC measuring system

    Journal of Fermentation and Bioengineering   Vol. 80 ( 1 ) page: 107-110   1995

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  286. Experimental fermentations of Ginjo sake with two fuzzy controls

    Seibutsu-kogaku Kaishi   Vol. 73 ( 4 ) page: 283-289   1995

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  287. Effective lactic acid production by two stage extractive fermentation

    Journal of Fermentation and Bioengineering   Vol. 79 ( 6 ) page: 589-593   1995

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  288. Effect of additives such as anti-oxidative agent on albumin secretion from primary culture of rat hepatocyte

    Biotechnology Letters   Vol. 17 ( 4 ) page: 365-370   1995

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  289. Reduction of virus infectivity in mixed liquor of activated sludge

      Vol. 16 ( 5 ) page: 339-345   1993

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Books 21

  1. *生物化学工学-バイオプロセスの基礎と応用-

    小林猛・田谷正仁編、本多裕之・上平正道・中島田豊・境愼司・清水一憲著( Role: Joint author)

    東京化学同人  2019.12 

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    Language:Japanese

    食品や医薬品の製造に深くかかわるバイオエンジニアリングを生物化学工学という視点でまとめた書籍。大学3年生向けの教科書として好適。

  2. 機能性ペプチドの探索技術(特集 機能性ペプチドの新展開)

    小﨑一功、本多裕之( Role: Joint author)

    ファインケミカル  2017 

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    Language:Japanese

  3. ペプチドアレイライブラリーの作成法と短鎖機能性ペプチドのスクリーニング

    本多裕之( Role: Sole author)

    技術情報協会  2017 

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    Language:Japanese

  4. 短鎖機能性ペプチドの探索

    本多裕之( Role: Sole author)

    生化学  2017 

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    Language:Japanese

  5. ペプチドアレイによる短鎖機能性ペプチドのスクリーニング

    本多裕之( Role: Sole author)

    化学と生物  2015 

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    Language:Japanese

  6. 磁性粒子を使った細胞工学~細胞機能評価への応用~

    92) 山本修平、大河内美奈、本多裕之( Role: Joint author)

    まぐね  2015 

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    Language:Japanese

  7. ペプチドインフォマティクスによる機能性ペプチドのデザイン

    本多裕之( Role: Sole author)

    高分子  2014 

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    Language:Japanese

  8. 磁力制御による一細胞解析

    87) 大河内美奈、本多裕之( Role: Joint author)

    生体医工学  2013 

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    Language:Japanese

  9. 磁性ナノ粒子を利用した細胞の挙動解析

    大河内美奈、本多裕之( Role: Joint author)

    化学センサ  2013 

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    Language:Japanese

  10. 再生促進型医療材料開発のための細胞選択的接着ペプチドの探索と応用

    蟹江 慧、加藤竜司、桑原史郎、成田裕司、本多裕之( Role: Joint author)

    生体医工学  2013 

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    Language:Japanese

  11. 医療機器コーティングのためのペプチドマテリアル

    86) 蟹江 慧、加藤竜司、成田裕司、本多裕之( Role: Joint author)

    バイオサイエンスとインダストリー  2010 

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    Language:Japanese

  12. コレステロール低下機能性食品のためのカタログペプチドアレイによる胆汁酸結合ペプチド探索

    加藤竜司、蟹江 慧、加賀千晶、大河内美奈、長岡 利、本多裕之( Role: Joint author)

    New Food Industry  2009 

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    Language:Japanese

  13. ペプチドアレイによるペプチドの機能計測評価と探索への応用

    本多裕之( Role: Sole author)

    化学工学  2008 

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    Language:Japanese

  14. The complementarity of the technical tools of tissue engineering and the concept of artifical organs for the design of functional bioartifical tissues

    79) Petoros Lenas, Angel Moreno, Laertis Ikonomou, Joerg Mayer, Hiroyuki Honda, Antonio Novellino, Camilo Pizarro, Eleni Nicodemou-Lena, Silvia Rodergas, Jesus Pintor( Role: Joint author)

    Thoughts and progress  2008 

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    Language:English

  15. 細胞の磁気操作による三次元組織の構築

    井藤 彰、本多裕之、上平正道( Role: Joint author)

    シーエムシー出版  2008 

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    Language:Japanese

  16. 生物情報解析を利用した機能性ペプチドの探索

    加賀千晶、野村茂幸、大河内美奈、加藤竜司、本多裕之:( Role: Joint author)

    2008 

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    Language:Japanese

  17. 生物工学ハンドブック

    日本生物工学会編( Role: Joint author)

    コロナ社  2007 

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    Language:Japanese

  18. 磁性ナノ粒子と磁力を利用した脱細胞血管への効果的な細胞播種方法

    清水一憲、井藤 彰、有延 学、村瀬洋介、岩田佳久、成田裕司、各務秀明、上田 実、本多裕之( Role: Joint author)

    生物工学会誌  2006 

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    Language:Japanese

  19. 図解バイオ活用技術のすべて

    東京工業大学大学院生命理工学研究科編( Role: Joint author)

    工業調査会  2004 

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    Language:Japanese

  20. *生物化学工学

    小林猛、本多裕之( Role: Joint author)

    東京化学同人  2002 

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    Language:Japanese

    食品や医薬品の製造に深くかかわるバイオエンジニアリングを生物化学工学という視点でまとめた書籍。大学3年生向けの教科書として好適。

  21. *生物工学序論(共著)

    ( Role: Joint author)

    講談社サイエンティフィック  1996 

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    Language:Japanese

    生物工学の入門書という視点でまとめた書籍。大学1、2年生向けの教科書として好適。

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Presentations 115

  1. 96穴方培養筋モデル収縮力評価系を用いた抗菌萎縮ペプチドの開発

    清水一憲、山本一貴、大隅早紀、長嶋拓則、秋山裕和、本多裕之

    第7回日本筋学会学術総会 

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    Event date: 2021.12

    Language:Japanese  

  2. コレステロール低下を目的としたギンナン由来生理活性ペプチドの探索

    竹内 友里・今井 健人・秋山 裕和・清水 一憲・本多 裕之

    第52回 中部化学関係学協会支部連合秋季大会 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  3. 96 ウェル型培養筋組織収縮力評価系を用いた抗筋萎縮ペプチドの探索

    山本 一貴, 大隅 早紀, 長島 拓則, 秋山 裕和, 本多 裕之, 清水 一憲

    第73回日本生物工学会大会 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  4. 細胞評価及び動物行動試験評価を用いた新規塩味ペプチドの発見

    竹内 友里・今井 健人・秋山 裕和・清水 一憲・本多 裕之

    第73回日本生物工学会大会 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  5. マイクロデバイス上での区画化三次元ヒト神経筋組織モデルの構築

    亀井 雄平, 山本 一貴, 秋山 裕和, 本多 裕之, 清水 一憲

    第73回日本生物工学会大会 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  6. 収縮力測定可能なマイクロデバイス上での神経筋オルガノイドの構築

    山本 一貴, 樋口 昌也, 秋山 裕和, 本多 裕之, 清水 一憲

    第73回日本生物工学会大会 

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    Event date: 2021.10

    Language:Japanese   Presentation type:Oral presentation (general)  

  7. 経口摂取を志向した貯蔵タンパク質由来生理活性ペプチドの機械学習による探索

    今井 健人・ 竹内 友里・ 清水 一憲・本多 裕之

    化学工学会第52回秋季大会 

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    Event date: 2021.9

    Language:Japanese   Presentation type:Oral presentation (keynote)  

  8. 焼成多孔性シリカゲルを用いた米タンパク質加水分解物からの生理活性ペプチドの濃縮

    羽川 瞳・ 今井 健人・ 高 紫維・ 谷口 正之・秋山 裕和・ 清水 一憲・本多 裕之

    化学工学会第52回秋季大会 

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    Event date: 2021.9

    Language:Japanese   Presentation type:Poster presentation  

  9. ペプチドアレイを用いた多変量解析によるプロテアーゼ切断部位予測

    森 陽子、清水 一憲、 田添 佳歩、 小川 翔大、本多 裕之

    化学工学会第86年会 (Online) 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  10. ヒト不死化骨格筋細胞を用いた筋萎縮組織モデルの構築とフェノタイプスクリーニングへの応用

    吉岡 慶太郎、山下 春来、清水 一憲、下村 沙也子、柴田 貴広、本多 裕之

    日本化学会第10回春季大会 (Online) 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  11. 骨格筋細胞の配向制御を用いたin vitro神経筋接合部モデルの開発

    葛西 晴郎、長島 拓則、古谷 太樹、山本 一貴、前川 忠儀、山岡 奈央、本多 裕之、清水 一憲

    化学工学会第86年会 (Online) 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  12. 培養運動筋モデルを用いた細胞外小胞の分泌特性評価

    村田朱里、本多裕之、清水一憲

    化学工学会第86年会 (Online) 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  13. 骨格筋細胞の配向制御によるアセチルコリン受容体の凝集促進

    山本一貴,清水一憲、本多裕之

    第20回日本再生医療学会 (Online) 

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    Event date: 2021.3

    Language:Japanese   Presentation type:Poster presentation  

  14. ヒト不死化骨格筋細胞を用いた筋萎縮組織モデルの構築とフェノタイプスクリーニングへの応用

    清水一憲、大隅早紀、長島拓則、 Stacy Hadiwidjaja、 村田朱里 、 久田拓海、加藤竜司、岡田洋平 、本多裕之

    シンポジウム「細胞アッセイ技術の現状と将来」 (Online) 

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    Event date: 2021.1

    Language:Japanese   Presentation type:Poster presentation  

  15. 骨格筋細胞の配向制御によるアセチルコリン受容体の凝集促進

    葛西晴郎、長島拓則、古谷太樹、前川忠儀、山岡奈央、本多裕之、清水一憲

    第6回日本筋学会学術集会 (Online) 

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    Event date: 2020.12

    Language:Japanese   Presentation type:Poster presentation  

  16. 神経筋疾患の解析のためのマイクロデバイスを用いた三次元神経筋組織の構築

    山本一貴,清水一憲、本多裕之

    第27回HAB研究機構学術年間 (Online) 

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    Event date: 2020.9

    Language:Japanese   Presentation type:Poster presentation  

  17. 神経筋疾患の解析と創薬のための三次元共培養デバイスの開発

    清水一憲,山岡奈央,長島拓則,今泉裕, 古谷太樹 ,伊藤卓治,岡田洋平,本多裕之

    シンポジウム「細胞アッセイ技術の現状と将来」 

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    Event date: 2020.1

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  18. 区画化デバイスと微小電極アレイを用いたヒトiPS由来神経筋の共培養と評価 International conference

    清水一憲伊藤卓治、岡田洋平、本多裕之

    シンポジウム「細胞アッセイ技術の現状と将来」 

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    Event date: 2020.1

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  19. Designs of functional peptides for oral intestinal delivery with a porous silica gel

    Kento Imai, Mijiti Maihemuti, Kazunori Shimizu, Satoshi Nagaoka, Hiroyuki Honda

    IcoFF2019 

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    Event date: 2019.12

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  20. Biochips for Single-Cell Analysis of Skeletal Muscle Myotubes and Motor Neurons with Neuromuscular Junctions

    Kazunori Shimizu, Nao Yamaoka, Yu Imaizumi, Takuji Ito, Yohei Okada, Hiroyuki Honda

    YABEC2019 

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    Event date: 2019.11

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  21. インビトロ神経支配筋組織構築のためのマイクロデバイス

    清水一憲、山岡奈央、長島拓則、今泉裕、伊藤卓治、岡田洋平、本多裕之

    化学とマイクロ・ナノシステム学会第40回研究会 

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    Event date: 2019.11

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  22. Development of a microdevice for fabricating in vitro innervated skeletal muscle tissues International conference

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    Event date: 2019.9

    Language:English   Presentation type:Oral presentation (general)  

  23. マイクロデバイスを用いたin vitro培養筋細胞・組織評価系の開発

    清水一憲、藤田英明、長森英二、本多裕之

    第2回 筋スマート社会実現コンソーシアム 講演会開 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  24. 生体内細胞位置を模倣した三次元神経筋共培養マイクロデバイスの開発

    中村 健人 , 清水 一憲 , 山岡 奈央 , 長島 拓則 , 今泉 裕 , 古谷 太樹 , 伊藤 卓治 , 岡田 洋平 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  25. ペプチドアレイを利用した環状ペプチドの構造と配列の最適化

    小崎 一功 , 鈴木 健弘 , 清水 一憲 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

  26. ジスルフィド架橋によるヘテロ二量体ペプチド合成法の開発と細胞内機能性ペプチド探索系への 応用

    小崎 一功 , 清水 一憲 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

  27. ヒト不死化筋芽細胞株 Hu5/KD3 を用いた三次元骨格筋組織の構築

    長島 拓則 , 清水 一憲 , Hadiwidjaja Stacy , 大隅 早紀 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  28. 共培養マイクロデバイスを搭載した微小電極アレイチップによる iPS 由来運動神経・骨格筋細胞評 価プロセスの開発

    古谷 太樹 , 清水 一憲 , 伊藤 卓治 , 岡田 洋平 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  29. マイクロラインパターンを用いた筋管細胞の配向制御によるアセチルコリン受容体の凝集促進

    葛西 晴郎 , 清水 一憲 , 長島 拓則 , 古谷 太樹 , 前川 忠義 , 山岡 奈央 , 本多 裕之

    第71回日本生物工学会大会 

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    Event date: 2019.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  30. Peptide array based synthetic method of hetero-dimeric peptides cross-linked by disulfide bond. International conference

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    Event date: 2019.9

    Language:English   Presentation type:Poster presentation  

  31. 運動神経支配された三次元培養筋組織構築のための マイクロデバイスの開発

    清水 一憲、山岡 奈央、今泉 裕、伊藤 卓治、岡田 洋平、 本多 裕之

    日本筋学会台5回学術集会 

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    Event date: 2019.8

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  32. 焼成多孔性シリカゲルを用いた苦味ペプチドの選択的除去手法の開発

    池田彩, 今井健人, 清水一憲,上村光浩, 小川光輝, 本多裕之

    第70回生物工学会大会 

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    Event date: 2018.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:関西大学 千里山キャンパス(吹田市)   Country:Japan  

  33. Inovative Reserch Center for Preventive Medical Engineering International conference

    Hiroyuki Honda

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    Event date: 2017.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:China  

  34. Development of Magnetic Force-Based Cell patterning Invited International conference

    Hiroyuki Honda

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    Event date: 2017.4

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Hwabaek International Convention Center, Korea.   Country:Korea, Republic of  

  35. アレルギー応答検出のための2種エピトープペプチドアレイの構築

    杉浦寿之、大河内美奈、本多裕之

    第65回日本生物工学会大会 

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    Event date: 2013.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:広島国際会議場   Country:Japan  

  36. 機能性ペプチドのデザインと細胞接着表面

    本多裕之

    第64回日本生物工学会大会 

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    Event date: 2012.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:神戸   Country:Japan  

  37. 磁性マイクロキャリアを用いた足場依存性細胞の1細胞遺伝子発現解析

    本多裕之、手島 翠、大河内美奈

    化学工学会第43回秋季大会 

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    Event date: 2011.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋   Country:Japan  

  38. アミロイド凝集促進ペプチドによる認知記憶障害の改善

    本多裕之、後藤宏明、加賀千晶、伊佐治弥生、大河内美奈、溝口博之、澤田誠

    日本生物工学会2010年度大会 

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    Event date: 2010.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  39. New designed apoptosis-inducing peptide by SPOT synthesized peptide array screening International conference

    Membaranomics 

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    Event date: 2010.9

    Language:English   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  40. 磁気剣山状デバイスを用いた単一細胞機能解析

    小出寛展、伊佐治弥生、大河内美奈、本多裕之

    化学工学会第42回秋季大会 

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    Event date: 2010.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  41. 3次元細胞アレイによる腫瘍細胞の浸潤評価

    小出 寛展、松村 拓、大河内 美奈、本多 裕之

    化学工学会第75年会 

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    Event date: 2010.3

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  42. 3次元細胞アレイによるがん細胞の浸潤評価、 磁性粒子を用いた細胞解析法の開発

    松村拓、小出寛展、高野翔、大河内美奈、本多裕之

    第17回HAB研究機構学術年会 

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    Event date: 2010.2

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  43. 遺伝子発現データおよび遺伝子多型データに基ずく疾患関連因子の探索と予測

    本多裕之

    第82回日本生化学会大会 

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    Event date: 2009.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  44. 糖尿病合併症リスク簡易モニタリング‐微量血液を用いた生体内酸化ストレス判定法

    伊佐治弥生、大河内美奈、本多裕之

    日本生物工学会2009年度大会 

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    Event date: 2009.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  45. 固相スポット合成短鎖ペプチドの分子認識

    本多 裕之、大河内 美奈、加藤 竜司

    化学工学会第41回秋季大会 

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    Event date: 2009.9

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  46. 混合正規分布を用いた心電図T派の近似と心電図QT間隔の推定への応用

    日比野 新、松原充孝、中杤昌弘、本多裕之、安井健二、植田典浩、堀場 充、神谷香一郎、児玉逸雄

    化学工学会第74年会 

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    Event date: 2009.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  47. 工学視点による機能性ペプチドの探索法の開発とその応用

    本多裕之、大河内美奈

    第17回日本バイオイメージング学会 

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    Event date: 2008.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  48. 糖尿病合併症リスク簡易モニタリング-正電荷基盤への親和性による赤血球酸化度判定法およびモデル動物を用いた評価

    本多裕之、伊佐治弥生、大河内美奈、小林美里、堀尾文彦

    日本生物工学会2008年度大会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  49. ミルクアレルギー診断のための高集密ペプチドアレイの作製と解析

    本多 裕之、加藤 竜司、竹下 敏一、大河内 美奈、川部 勤、松島 充代子、松本 直樹、坂本 龍雄、廣瀬 悦子、川瀬 三雄、吉田 安子、高瀬 智和、小川 昭子

    化学工学会第40回秋季大会 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  50. ミルクアレルギー診断を目指した高集密ペプチドアレイの作成とIgEエピトープ解析

    本多裕之、大河内美奈、加藤竜司、竹下敏一、川部 勤、松島充代子、松本直樹、坂本龍雄、廣瀬悦子、川瀬三雄、吉田安子、高瀬智和、小川昭子、伊藤浩明

    第3回バイオ関連化学合同シンポジウム2008 

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    Event date: 2008.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  51. ファージディスプレイ法に代わる機能性ペプチド探索法

    本多裕之、大河内美奈、加藤竜司

    第3回バイオ関連化学合同シンポジウム2008 

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    Event date: 2008.9

    Language:Japanese  

  52. 磁性微粒子を用いた液滴ハンドリングによる細胞計測

    第6回ライフサーベイヤシンポジウム 

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    Event date: 2008.6

    Language:Japanese   Presentation type:Poster presentation  

    Country:Japan  

  53. ペプチドアレイを用いた胆汁酸高結合ペプチドのデザイン

    加賀千晶、森川健正、山下佑加、加藤竜司、大河内美奈、長岡利、本多裕之

    日本化学会第88年会 

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    Event date: 2008.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  54. 磁気細胞アレイを用いた1細胞解析

    伊野浩介、大河内美奈、小西奈緒、今井連太郎、式田光宏、本多裕之

    化学工学会第73年会 

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    Event date: 2008.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  55. 内視鏡的粘膜切除術術語食道狭窄の予防に対する注入型薬剤除放リポソームキャリアの開発

    有延 学、加藤竜司、多々内暁光、本多裕之、成田祐司

    第7回日本再生医療学会 

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    Event date: 2008.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  56. Both pneumatic and magnetic induction of scattered cells on micro channel array for cellular analysis International conference

    MEMS2008 

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    Event date: 2008.1

    Language:English   Presentation type:Poster presentation  

  57. 磁石を駆動力とした微小液滴操作による遺伝子解析用マイクロデバイスの開発

    大河内美奈、土屋裕義、長尾宣洋、式田光宏、本多裕之

    第80回日本分子生物学会生化学会合同大会 

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    Event date: 2007.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  58. Magnetic force-based cell patterning for tissue engineering International conference

    ICCMB(International Conference on Cellular & Molecular Biology 

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    Event date: 2007.12

    Language:English   Presentation type:Oral presentation (general)  

  59. Motif detection and classification method in peptide sequences using genetic programming International conference

    GIW2007 

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    Event date: 2007.12

    Language:English   Presentation type:Poster presentation  

  60. 内視鏡的粘膜切除術術後食道狭窄の予防に対する注入型薬剤溶出キャリアを用いた再生医療的治療

    有延 学、多々内暁光、加藤竜司、本多裕之、成田祐司

    第10回日本組織工学会 

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    Event date: 2007.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  61. MCL-manipulation device for the optimization of cell culture condition International conference

    YABEC2007 

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    Event date: 2007.10

    Language:English   Presentation type:Poster presentation  

  62. 高機能生酵素の効果的デザインのための知識情報処理を用いた新規手法の提案

    冨田康之、木村昌博、中野秀雄、則武智哉、吉田洋一、加藤竜司、大河内美奈、本多裕之

    日本生物工学会平成19年度大会 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  63. 知識情報処理を用いた高機能性酵素の効率的デザイン

    冨田康之、加藤竜司、大河内美奈、本多裕之

    社)日本農芸化学会 2007年度関西支部・中部支部合同大会( 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  64. グラフィカル情報解析による有効生物情報の新規抽出方法の開発(CG-GAM)

    中杤昌弘、本多裕之

    化学工学会第39回秋季大会 

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    Event date: 2007.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  65. A cell patterning technique using magnetic force International conference

    The 2nd International Workshop on Approaches to Single-Cell Analysis (Tokyo, Japan) 2007.9.6-7 

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    Event date: 2007.9

    Language:English   Presentation type:Poster presentation  

    Country:Japan  

  66. Application of mesenchymal stem cell sheets constructed by using magnetite nanoparticles and magnetic force to bone tissue engineering

    Biochemical Engineering XV Engineering Biology from Biomolecules to Complex System 

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    Event date: 2007.7

    Language:English   Presentation type:Poster presentation  

  67. 知的情報処理解析を利用した新規機能性ペプチドデザイン手法の提案

    日本化学会第87年会 

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    Event date: 2007.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  68. 情報処理を用いたペプチドスクリーニングの効率化

    加藤竜司、加賀 千晶、国松 己歳、大河内 美奈、本多 裕之

    化学工学会第72年会 

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    Event date: 2007.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  69. ナノ微粒子を用いた生体組織構築

    本多裕之、清水一憲、伊野浩介、井藤 彰

    バイオ・マイクロシステム研究会 

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    Event date: 2007.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  70. 遺伝子多型、環境因子を用いた多因子疾患の発症予測のための新規解析手法の開発

    冨田康之、横田充弘、本多裕之

    第7回バイオ情報学研究会 

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    Event date: 2006.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  71. Preposal of graphic assessment method of attribute significance for comprehensive combination analysis International conference

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    Event date: 2006.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  72. 生きたペースメーカーの作成を目指した磁性ナノ粒子を用いた心筋組織構築

    清水一憲、吉田達郎、井藤 彰、李鐘国、児玉逸雄、沢口靖、室原豊明、本多裕之

    第17回日本MRS学術シンポジウム 

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    Event date: 2006.12

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  73. Bioinformatic apporoadh to interpret the flexibility of extra-cellular matrixes International conference

    Ryuji Kato, Chiaki Kaga, Yasuyuki Tomita, Mina Okochi, Hiroyuki Honda

    RECOMB Satellite Conferences on System Biology and Computational Proteomics 

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    Event date: 2006.12

    Language:English   Presentation type:Oral presentation (general)  

  74. A novel methodology of cell micropatterning using functional magnetite nanoparticles and magnetic force International conference

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    Event date: 2006.11

    Language:English   Presentation type:Oral presentation (general)  

  75. Cell micropatterning using magnetite nanoparticles and magnetic force International conference

    AIChE (The 2006Annual Meeting 

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    Event date: 2006.11

    Language:English   Presentation type:Oral presentation (general)  

  76. Peptide informatics ~ novel method for screening and design of biologically active peptides International conference

    43JPS・PEM4 (International Conference of 43rd Japanese Peptide Symposium/4th Peptide Engineering Meeting 

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    Event date: 2006.11

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  77. Design of cell adhesion peptide by bioinformatics

    The International Symposia for Bioimaging 

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    Event date: 2006.10

    Language:English  

    Country:Japan  

  78. Magnetic bead-droplet handling for biochemical reactions in Micro-TAS International conference

    The 23th Sensor Symposium on Sensors,Micromachine and Appied Systems 

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    Event date: 2006.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  79. Application of bioinformatic predication for supporting high-throughput experiments in proteome International conference

    4th International Forum on Post—genome Technology 

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    Event date: 2006.9

    Language:English  

  80. トランスクリプトーム解析による疾患診断治療~可能性と問題点

    化学工学会第38回秋季大会 

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    Event date: 2006.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  81. 遺伝子発現情報解析による有機溶媒耐性遺伝子の探索

    本多裕之、大河内美奈

    日本生物工学会平成18年度大会 

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    Event date: 2006.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  82. Reconstruction of cell-cell communication : multilayered cardiomycyte sheets using magnetite nanoparticles and magnetic force International conference

    The 1st International Workshop on Approaches to Single-Cell Analysis 

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    Event date: 2006.6

    Language:English   Presentation type:Oral presentation (general)  

  83. 疾患関連遺伝子の遺伝子選択法

    本多裕之、高橋広夫、河村敬司

    化学工学会第71年会 

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    Event date: 2006.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  84. ペプチドチップを用いたHsp70結合ペプチド癌ワクチンの探索

    林 宏樹、大河内美奈、井藤 彰、本多裕之

    日本化学会第86年会 

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    Event date: 2006.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  85. New reliable cancer diagnosis method using boosting and projective adaptive resonance theory

    GIW2005 

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    Event date: 2005.12

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  86. 磁性微粒子を用いた移植可能な間葉系幹細胞シートの作製

    吉田 達郎、清水 一憲、井藤 彰、本多 裕之、山田 陽一、上田 実

    日本生物工学会平成17年度大会 

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    Event date: 2005.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  87. In vitro expansion of human mesenchymal stem cells using magnetic force and antibody-conjugated magnetoliposomes International conference

    第7回アジアシンポジウム 

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    Event date: 2005.11

    Language:English   Presentation type:Oral presentation (general)  

  88. 磁性ナノ微粒子を用いた再生医療~ナノメディシンによる先端医療~

    本多裕之、井藤 彰

    第14回バイオイメージング学会学術集会 

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    Event date: 2005.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  89. インフォマティクス解析を組み合わせた新規機能性リパーゼの目的志向的探索

    本多裕之、加藤竜司、小林 猛、中野秀雄、小西裕之、加藤克也、山根恒夫

    酵素工学研究会第54回講演会 

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    Event date: 2005.10

    Language:Japanese  

    Country:Japan  

  90. Construction of Multilayered Cell Sheets Using Magnetic Nanoparticles and Magnetic Force International conference

    8th TESI Annual Meeting 

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    Event date: 2005.10

    Language:English   Presentation type:Oral presentation (general)  

  91. Screening of cell death inclucible peptides from TRAIL sequence

    第78回日本生化学会大会 

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    Event date: 2005.10

    Language:English  

    Country:Japan  

  92. Heart immunotherapy using magnetic nano-particl

    Biomedical and biomechanical engineering (バイオニクスと自然に学ぶ技術の日独ワークショップ) 

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    Event date: 2005.10

    Language:English  

    Country:Japan  

  93. 未熟樹状細胞を用いたHeat Immunotherapy の開発

    井藤 彰、田中功二、小林 猛、川村龍吉、島田眞路、松本和彦、斎田俊明、本多裕之

    日本ハイパーサーミア学会第22回大会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  94. 二項検定に基づく遺伝子多型、環境因子の組み合わせ解析による心筋梗塞発症要因の推定

    本多裕之、冨田康之、横田充弘

    第53回日本心臓病学会学術集会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  95. ナノバイオブロックとしての機能性ペプチドの検索とデザイン

    化学工学会第37回秋季大会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  96. 射影適応共鳴理論とブースティングを用いた新しいガン診断手法

    本多裕之、高橋広夫

    第64回日本癌学会学術総会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  97. 機能性磁性ナノ粒子を用いた管状組織の構築

    井藤 彰、伊野浩介、各務秀明、上田 実、本多裕之

    第8回日本組織工学会 

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    Event date: 2005.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  98. A new method with boosting and projective adaptive resonance theory for analysis of gene expression from cancer patients International conference

    ECB12 (12th European Congress on Biotechonology) 

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    Event date: 2005.8

    Language:English   Presentation type:Oral presentation (general)  

  99. Classification method for predication of multifactorial disease development using interaction between genetic and environmental factors International conference

    CSB2005(2005 IEEE Computational System Bioinformatics Conference) 

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    Event date: 2005.8

    Language:English   Presentation type:Oral presentation (general)  

  100. 癌だけを加熱する新しい治療法 ―温熱免疫療法―

    21世紀COEシンポジウム「自然の叡智に学ぶ“ものずくり”」 

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    Event date: 2005.8

    Language:Japanese  

    Country:Japan  

  101. 多因子疾患発症に関連する複合リスク因子の探索と発症パターン分類~心筋梗塞遺伝子多型データを対象として~

    冨田康之、本多裕之、横田充弘

    第6回日本がん分子免疫学研究会学術集会 

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    Event date: 2005.5

    Language:Japanese  

    Country:Japan  

  102. A Novel Cell Adhesion Peptide Screening System using Peptide Array International conference

    APBioChEC`05 

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    Event date: 2005.5

    Language:English   Presentation type:Oral presentation (general)  

  103. Regenerative medicine utilizing magnetic beads International conference

    INTERMAG2005 

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    Event date: 2005.4

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  104. ブースティングとファジィ理論を組み合わせた高速で信頼性の高いガン診断手法の開発

    高橋広夫、本多裕之

    化学工学会第70年会 

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    Event date: 2005.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  105. 磁性ナノ粒子を用いた組織工学手法の開発

    井藤 彰、各務秀明、上田 実、本多裕之

    第4回日本再生医療学会総会 

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    Event date: 2005.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  106. ナノ磁性微粒子を用いた生体組織構築

    本多裕之、井藤 彰

    第13回日本バイオイメージング学会 

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    Event date: 2004.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  107. Construction of Multilayered Cell Sheets Using Magmetite Nanoparticles and Magnetic Force

    第10回APCChE2004 

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    Event date: 2004.10

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  108. 磁性微粒子を用いたハイパーサーミア

    井藤 彰、小林 猛、本多裕之

    日本ハイパーサミア学会第21回大会 

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    Event date: 2004.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  109. Several Genes Selected by Gene Expression profiles Increased Organic Solvent Tolerance in Escherichia coli International conference

    YABEC2004 

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    Event date: 2004.9

    Language:English   Presentation type:Oral presentation (general)  

    Country:Japan  

  110. 新規エナンチオ選択的リパーゼデザインのための知識情報処理

    加藤竜司、小西裕之、加藤克也、古賀雄一、山根恒夫、中野秀雄、小林 猛、本多裕之

    日本生物工学会大会2004 

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    Event date: 2004.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  111. ペプチドチップを用いた細胞殺傷ペプチドの検索

    加藤竜司、奥野郁佳子、小林 猛、本多裕之

    日本化学関係学協会支部連合協議会(名古屋大学東山キャンパス) 2004. 9.17-18・ ・ : 

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    Event date: 2004.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  112. 機能性磁性微粒子を用いた三次元生体組織の構築-Mag-TEの開発-

    井藤 彰、各務秀明、上田 実、本多裕之

    第7回日本組織学会(東京) 2004.7.1-2・ : 

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    Event date: 2004.7

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  113. Peptide Array based Cell-Assay for Novel Peptide Design International conference

    Cambridge Healthtech Institute Beyond Genome2004 

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    Event date: 2004.6

    Language:English   Presentation type:Oral presentation (general)  

  114. DNAマイクロアレイデータからの疾患関連遺伝子探索ツールGeneFISの開発

    本多裕之、小林 猛

    化学工学会第69年会 

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    Event date: 2004.4

    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  115. トリプシン加水分解で生じる単鎖ペプチドのコレステロールミセル崩壊活性

    伊藤雅子、清水一憲、本多裕之

    日本農芸化学会2020年度大会(コロナで中止) 

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Research Project for Joint Research, Competitive Funding, etc. 17

  1. ペプチドアレイによる二次胆汁酸結合ペプチドの解析

    2021.4 - 2022.3

    国内共同研究 

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    Authorship:Principal investigator 

    Direct Cost: \1538462 )

  2. ペプチドアレイを利用した食品プロテアーゼの基質特異性の解明

    2019.4 - 2021.3

    国内共同研究 

  3. ペプチドアレイを利用した食品プロテアーゼの基質特異性の解明

    2018.4 - 2019.3

    国内共同研究 

  4. 中長鎖ペプチドの腸輸送を目指した多孔性無機材料の内表面設計

    2017.7 - 2018.3

    受託研究 

  5. 共生バイオフイルム計測用デバイスに関する研究

    2015.4 - 2017.3

    学内共同研究 

  6. 多次元的生物情報解析を基盤とした、発酵における目的物質の生産量や類縁体生成量への影響因子の特定

    2013.10 - 2016.3

    学内共同研究 

  7. 超早期診断技術開発プロジェクト

    2013.6 - 2016.3

    国内共同研究 

  8. ペプチドアレイ技術による配列網羅的解析を基盤おした、ミルクたんぱく質の抵抗原化に関する研究、及び、機能性ペプチドに関する研究

    2013.6 - 2015.3

    学内共同研究 

  9. サイトカイン認識ペプチドの探索

    2013.2 - 2013.7

    学内共同研究 

  10. 磁性微粒子を利用したイソプロパノール高生産株、高耐性株のハイスループット選択

    2012.10 - 2017.3

    特色ある大学教育支援プログラム 

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    Grant type:Competitive

    磁性微粒子ラベリング技術を用いた1藻類細胞アレイを作製し、イソプロパノール高生産、高耐性を持つ変異藻類を迅速に探索する。このため、培養藻類が磁気分離できる磁性ナノ微粒子を作製し、1藻類細胞を液滴に隔離し、オイルで封入した培養器中で孤立培養する。また、磁気分離を用いて数万細胞の特性を一気に探索できるハイスループット選択システムを構築し、高機能細胞をスクリーニングする。本研究の成功には高性能藻類を迅速に探索・分離する技術の確立が重要である。磁気分離は1細胞の機能評価には優れた方法であり、磁気ハンドリングと液滴操作は名古屋大学で確立された他に類を見ない手法である。

  11. 機能性ペプチドの探索

    2012.5 - 2014.3

    学内共同研究 

  12. 大豆タンパク質に含まれる生理機能ペプチドの探索

    2010.4 - 2010.9

    学内共同研究 

  13. 筋細胞シート応力測定技術を用いた初代筋細胞と株化筋細胞の比較

    2008.7 - 2009.3

    学内共同研究 

  14. ニューラルネットワークによるヒト肝障害予測モデルの構築

    2008.4 - 2008.7

    学内共同研究 

  15. 分析・診断医工学による予防早期医療の創生

    2007.4 - 2008.3

    学内共同研究 

  16. 癌の温熱療法に関する研究

    2004.4 - 2005.3

    学内共同研究 

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    磁性微粒子を発熱素子とする局所癌温熱免疫療法に用いる磁性微粒子製剤のデザインを最適化するとともに製剤の製法・規格を確立した。また、悪性皮膚がんを発症するトランスジェニックマウスを用いて癌の温熱免疫療法の動物モデルにおける有用性を検討した。

  17. Analysis of organic solvent tolerance mechanism of Echerichia coli

    2001 - 2003

    Cooperative Research within Japan 

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KAKENHI (Grants-in-Aid for Scientific Research) 13

  1. 革新的エクササイズメディスンの創出を目指した運動EVsの分泌特性と機能の解明

    2021.7 - 2023.3

    科学研究費補助金 

    本多 裕之

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    Authorship:Principal investigator 

  2. 革新的エクササイズメディスンの創出を目指した運動EVsの分泌特性と機能の解明

    Grant number:21K18848  2021.7 - 2023.3

    科学研究費助成事業  挑戦的研究(萌芽)

    本多 裕之, 清水 一憲

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    Authorship:Principal investigator 

    Grant amount:\6500000 ( Direct Cost: \5000000 、 Indirect Cost:\1500000 )

    収縮運動する培養骨格筋細胞から分泌される細胞外小胞(運動EVs)は、分解抵抗性・標的指向性をもつ革新的なバイオ医薬品として期待される。しかしこれまでに、運動EVsの分泌や機能に関する基本特性の解明は十分に進んでいない。本研究では、我々が独自に開発したデバイスを使って構築するin vitro運動モデルを用いて、運動EVsの分泌特性(量と質)と機能の解明に挑戦する。本研究で得られる成果は、次世代バイオ医薬品となりうる運動EVsの大量生産を実現するために欠かすことのできない生物工学の観点から非常に重要な知見となる。

  3. Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein

    Grant number:20H00570  2020.4 - 2024.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

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    Authorship:Coinvestigator(s) 

  4. Exploring of functional peptides from edible proteins and establishment of oral administration without activity loss

    Grant number:19H00837  2019.4 - 2023.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

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    Authorship:Principal investigator 

    Grant amount:\45890000 ( Direct Cost: \35300000 、 Indirect Cost:\10590000 )

  5. Fundamental study on the lipid lowering peptides derived from food proteins

    Grant number:17H00817  2017.4 - 2020.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (A)

    Nagaoka Satoshi

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    Authorship:Coinvestigator(s) 

    We have discovered that lactostatin (IIAEK), a peptide that improves cholesterol (CHOL) metabolism, affects the intestinal CHOL metabolism-improving gene (ABCA1) through specific activation of alkaline phosphatase. The first CHOL metabolism-improving dipeptide FP (phenylalanine-proline) was discovered from 400 dipeptides in the world. Nine soybean β-conglycinin-derived peptides with 3 to 8 amino acid residues were detected in rat whole body plasma.

  6. 細胞分子確認ペプチドのデザインと細胞機能改変

    2016.4 - 2019.3

    科学研究費補助金  基盤研究(B)

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    Authorship:Principal investigator 

  7. The design of the cell internal division child confirmation peptide and cell function alteration

    Grant number:16H04575  2016.4 - 2019.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (B)

    HONDA HIROYUKI

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    Authorship:Principal investigator 

    Grant amount:\17810000 ( Direct Cost: \13700000 、 Indirect Cost:\4110000 )

    Peptides that have biological activities are called functional peptides. Many types of functional peptides have been found to date and has been designed for development of peptide drug. In the present study, following 3 topics were investigated, 1) fabrication of peptide library including unnatural amino acid, 2) screening of intracellular functional peptide conjugated with cell penetrating peptide (CPP), 3) development of the smart machinery for removal of CPP in intracellular space. Related to the last topic, we have established the methodology for disulfide bond formation of all peptides on peptide array. In addition, we have been developed a novel synthesis method of hetero-dimerized peptide using intramolecular disulfide bonding between main- and sub-chain of lysin.

  8. 細胞アレイ評価法を用いた細胞内機能性ペプチド探索技術の確立

    2013.4 - 2016.3

    科学研究費補助金  基盤研究(B)

    本多裕之

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    Authorship:Principal investigator 

  9. 磁気細胞パターニングによる1細胞機能解析法の確立

    2009.4 - 2012.3

    科学研究費補助金  基盤研究(B)

    本多裕之

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    Authorship:Principal investigator 

  10. Peptide Informatics

    2005.4 - 2008.3

    Grant-in-Aid for Scientific Research 

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    Authorship:Principal investigator 

  11. Screening of horming peptide using peptide array

    2005 - 2007

    Grant-in-Aid for Scientific Research 

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    Authorship:Coinvestigator(s) 

  12. life survayer

    2005

    Grant-in-Aid for Scientific Research 

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    Authorship:Coinvestigator(s) 

  13. Outcome prediction of cancer patient from gene expression profiles using fuzzy neural network

    2001 - 2003

    Grant-in-Aid for Scientific Research 

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Industrial property rights 44

  1. 分化細胞の生産方法およびiPS細胞の未分化細胞の除去方法

    本多裕之, 清水一憲, 松本凌, 堀勝, 水野正明, 吉川史隆, 田中宏昌

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    Applicant:国立大学法人名古屋大学

    Application no:特願2015-155312  Date applied:2015.8

    Country of applicant:Domestic  

  2. IgE結合性エピトープペプチドの利用

    大河内美奈,本多裕之,神谷知宏、荻原沙緒理、山内 望

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    Applicant:国立大学法人名古屋大学、倉敷紡績株式会社

    Application no:特願2015-020989  Date applied:2015.2

    Country of applicant:Domestic  

  3. ミルクアレルギー個体の属性の予測方法

    大河内 美奈,本多 裕之,吉田 安子, 小郷 和彦

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    Application no:特願2013-266063  Date applied:2013.12

    Announcement no:特開2015-121495 

    Country of applicant:Domestic  

  4. 蛍光プローブ及び検出方法

    本多裕之、大河内美奈、杉田智哉

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    Applicant:国立大学法人 名古屋大学

    Application no:特願2013-239263  Date applied:2013.11

    Country of applicant:Domestic  

  5. 末梢循環腫瘍細胞又は希少細胞分離用デバイス

    中西速夫、伊藤誠二、絹田精鎮、市野沢義行、遊佐亜希子、本多裕之、大河内美奈

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    Applicant:㈱オプトニクス精密、公益財団法人科学技術交流財団、国立大学法人名古屋大学

    Application no:特願2013-153717  Date applied:2013.7

    Country of applicant:Domestic  

  6. 骨新生用組成物及び骨新生システム

    西田佳弘、生田国大、本多裕之、加藤竜司、小林 猛

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    Applicant:国立大学法人 名古屋大学

    Application no:特願2013-128021  Date applied:2013.6

    Announcement no:WO 2014/203738 A1 

    Country of applicant:Domestic  

  7. 酸化ストレス評価法及びその用途

    本多裕之、大河内美奈、伊佐治弥生、濱田、長崎

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    Applicant:国立大学法人名古屋大学

    Application no:特願2011-519851  Date applied:2011.12

    Announcement no:WO 2010/147206 

    Patent/Registration no:PCT/JP2010/060347  Date registered:2011.1 

    Country of applicant:Foreign country  

  8. アレルギー疾患の診断方法

    本多裕之、大河内美奈、加藤竜司、松本直樹、川部 勤、松島充代子、吉田安子、高瀬智和、日本硝子株式会社

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    Applicant:国立大学法人名古屋大学

    Application no:PCT/JP2010/0055456(WO)  Date applied:2010.10

    Country of applicant:Foreign country  

  9. 培養細胞評価装置、インキュベータおよびプログラム

    株ニコン、加藤竜司、本多裕之、山本若菜、名倉良英、古谷史旺

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    Applicant:国立大学法人名古屋大学、㈱ニコン

    Application no:PCT/JP2010/005119(WO)  Date applied:2010.8

    Country of applicant:Foreign country  

  10. 高親和性ペプチドの設計法及び調整法、並びに高親和性ペプチド

    本多裕之、大河内美奈、加賀千晶、冨田康之、加藤竜司

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    Applicant:国立大学法人名古屋大学

    Application no:11/882,512(US)  Date applied:2010.6

    Country of applicant:Foreign country  

  11. 培養細胞評価装置、インキュベータ、細胞評価方法、細胞評価プログラムおよび細胞の培養方法

    本多裕之、加藤竜司、名倉良英

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    Applicant:国立大学法人名古屋大学、株式会社ニコン

    Application no:特願2010-100162  Date applied:2010.4

    Country of applicant:Domestic  

  12. アレルゲンのエピトープ又はその候補の検出方法及びその利用

    本多裕之、大河内美奈、加藤竜司、松本直樹、川部勤、松島充代子、吉田安 子、高瀬智和

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    Applicant:国立大学法人名古屋大学・日本碍子㈱

    Application no:PCT/JP2009/005997(WO)  Date applied:2009.11

    Country of applicant:Domestic  

  13. 乳酸菌の付着性を誘導するペプチドおよびその用途

    本多裕之、大河内美奈、杉田智哉

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    Applicant:国立大学法人名古屋大学

    Application no:特願2009-189756  Date applied:2009.8

    Country of applicant:Domestic  

  14. アレルギー疾患の診断方法

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    Application no:特願2009-077402  Date applied:2009.3

    Country of applicant:Domestic  

  15. 機能性ペプチドを表すルールの抽出法、機能性ペプチドの設計法及び調整法、ポリペプチド又はポリペプチド含有組織物の評価法、並びに機能性ペプチド

    本多裕之、大河内美奈、加藤竜司、加賀千晶、蟹江 慧、長岡 利

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    Applicant:国立大学法人名古屋大学

    Application no:特願2009-71498  Date applied:2009.3

    Country of applicant:Domestic  

  16. 培養状態評価装置、インキュベータ及びプログラム

    本多裕之、加藤竜司、山本若菜

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    Applicant:国立大学法人名古屋大学・ニコン

    Application no:特願2009-044375  Date applied:2009.2

    Country of applicant:Domestic  

  17. がん細胞挙動評価モデル及びその用途

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    Application no:特願2008-286173  Date applied:2008.11

    Country of applicant:Domestic  

  18. アレルゲンのエピトープ又はその候補の検出方法及びその利用

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    Application no:特願2008-316216  Date applied:2008.11

    Country of applicant:Domestic  

  19. アミロイドβ凝集促進ペプチド及びその用途

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    Application no:特願2008-228974  Date applied:2008.9

    Country of applicant:Domestic  

  20. ペプチド固定化溶液及びその利用

    本多裕之、大河内美奈、松本直樹、川部 勤、松島充代子、川瀬三雄、吉田安子、高瀬智和

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    Applicant:国立大学法人名古屋大学・日本碍子㈱

    Application no:特願2008-018006  Date applied:2008.1

    Country of applicant:Domestic  

  21. 酸化ストレス評価法及びその用途

    本多裕之、大河内美奈、伊佐治弥生

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    Applicant:国立大学法人名古屋大学

    Application no:特願2007-332529  Date applied:2008.1

    Country of applicant:Domestic  

  22. 細胞の固定化法及び抗体の製造法品質を予測する予測モデルの構築法、予測モデルの構築用プログラム、該プログラムを記録した記録媒体、予測モデルの構築用装置

    本多裕之、加藤竜司、山本若菜、冨田康之、中杤昌弘、名倉良英、蛯沢克己、各務秀明、上田 実

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    Applicant:国立大学法人名古屋大学

    Application no:特願2007-212116  Date applied:2007.8

    Announcement no:特開2009-44974 

    Country of applicant:Domestic  

  23. 細胞構造体の形成方法

    本多裕之、井藤 彰、伊野浩介、児玉逸雄、李鐘國

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    Applicant:国立大学法人名古屋大学

    Application no:PCT/JP2007/050769  Date applied:2007.1

    Country of applicant:Domestic  

  24. 高親和性ペプチドの設計法及び調整法、並びに高親和性ペプチド

    本多裕之、大河内美奈、加賀千晶、冨田康之、加藤竜司

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    Applicant:国立大学法人名古屋大学

    Application no:特願2006-0243883  Date applied:2006.9

    Country of applicant:Domestic  

  25. 酸化ストレス評価法及びその用途

    本多裕之、大河内美奈、伊佐治弥生

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    Applicant:国立大学法人名古屋大学

    Application no:特願2009-147094  Date applied:2006.6

    Country of applicant:Domestic  

  26. 細胞死誘導ペプチド、MAP化細胞死誘導ペプチド、細胞死誘導剤及び抗癌剤

    中西麻里、大河内美奈、加藤竜司、小林 猛、本多裕之

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    Applicant:国立大学法人名古屋大学

    Application no:特願2006-048016  Date applied:2006.4

    Country of applicant:Domestic  

  27. 細胞構造体の形成方法

    本多裕之、井藤 彰、伊野浩介、児玉逸尾、李鐘国

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    Applicant:国立大学法人名古屋大学

    Application no:特願2006-093364  Date applied:2006.3

    Country of applicant:Domestic  

  28. 高親和性ペプチドの設計法及び調整法、並びに高親和性ペプチド

    齋藤永宏、高井 治、呉 雲影、本多裕之、井藤 彰

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    Applicant:国立大学法人名古屋大学

    Application no:PCT/JP2006/306498  Date applied:2006.3

    Country of applicant:Domestic  

  29. 抗HMW-MAA抗体を結合した磁性微粒子

    小林 猛、井藤 彰、本多裕之、斎田俊明、アメリカ合衆国、ニューヨーク州14202,バッファロー市、リバーミスト・ドライブ180 ソルダーノ・フェローネ

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    Applicant:小林 猛、株式会社ティーティーシー

    Application no:特願2005-093846  Date applied:2005.3

    Country of applicant:Domestic  

  30. 細胞培養方法および培養細胞体

    井藤 彰、本多裕之、小林 猛

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    Applicant:本多裕之、株式会社ジャパン・ティッシュ・エンジニアリング

    Application no:特願2004-135468  Date applied:2004.4

    Country of applicant:Domestic  

  31. 細胞死誘導のためのペプチド

    本多裕之、小林 猛、国松巳歳、加藤竜司、奥野郁佳子

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    Applicant:国立大学法人名古屋大学

    Application no:特願2004-124338  Date applied:2004.4

    Country of applicant:Domestic  

  32. 細胞培養方法

    井藤 彰、本多裕之、小林 猛、上田 実、各務秀明、畠 賢一郎、岩崎浩子

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    Applicant:本多裕之、J-TEC㈱

    Application no:特願2005-503651  Date applied:2004.3

    Patent/Registration no:特許第4504920  Date registered:2010.4 

    Country of applicant:Domestic  

  33. 新規リポソーム

    井藤 彰、本多裕之、小林 猛

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    Applicant:小林 猛

    Application no:特願2004-049423  Date applied:2004.2

    Country of applicant:Domestic  

  34. 化学分析装置及び化学分析方法

    式田光宏、佐藤一雄、本多裕之、井内紘太

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    Applicant:独立行政法人科学技術振興機構

    Application no:特願2004-8415  Date applied:2004.1

    Country of applicant:Domestic  

  35. 細胞死誘導のためのペプチドおよび医薬

    小林猛、本多裕之、国松己歳、加藤竜司、奥野郁佳子

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    Applicant:国立大学法人名古屋大学

    Application no:特願2003-287727  Date applied:2003.8

    Country of applicant:Domestic  

  36. 医用材料

    小林猛、本多裕之、井藤彰、間瀬敦則、瀧澤洋平、新海 政重

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    Applicant:財団法人名古屋産業科学研究所

    Application no:特願2003-78964  Date applied:2003.3

    Country of applicant:Domestic  

  37. 細胞培養方法

    井藤彰、本多裕之、小林猛、上田実、各務秀明、畠賢一郎

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    Applicant:ジャパン・ティッシュ・エンジニアリング

    Application no:特願2003-46060  Date applied:2003.2

    Patent/Registration no:特許第4160842 

    Country of applicant:Domestic  

  38. 遺伝子発現データの処理方法

    小林猛、本多裕之、花井泰三、安藤達哉

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    Applicant:(財)名古屋産業科学研究所

    Application no:2002-175631  Date applied:2002.6

  39. 意思伝達支援装置、及び意思伝達支援ソフトウェア

    小林猛、本多裕之、花井泰三、日比野新、白滝龍昭

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    Applicant:(財)名古屋産業科学研究所

    Application no:2002-136406  Date applied:2002.5

    Country of applicant:Domestic  

  40. がんの温熱療法における免疫賦活剤

    小林猛、新海政重、本多裕之、上野健吾、大塚健三

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    Applicant:(株)TTC

    Application no:PCT/JP01/09381  Date applied:2001.11

    Country of applicant:Foreign country  

  41. 植物培養細胞からの長期間安定な物質生産方法

    小林猛、本多裕之、長森英二、平岡浩佑

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    Applicant:名古屋大学長

    Application no:2001-60225  Date applied:2001.3

  42. 遺伝子のクラスタリング方法

    小林猛、本多裕之、花井泰三、冨田秀太

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    Applicant:(財)名古屋産業科学研究所

    Application no:2000-373765  Date applied:2000.12

    Announcement no:2002-175306 

    Country of applicant:Domestic  

  43. 増粘剤添加による再分化植物体の効率的生産方法

    小林猛、本多裕之、長森英二

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    Applicant:名古屋大学長

    Application no:2001-153123  Date applied:2000.5

    Announcement no:2001-128572 

    Country of applicant:Domestic  

  44. 磁石配置方法及び磁気誘導方法

    小林猛、新海政重、本多裕之、瀧千智

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    Applicant:名古屋大学長

    Application no:2000-060138  Date applied:2000.3

    Announcement no:2001-250715 

    Country of applicant:Domestic  

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Teaching Experience (On-campus) 65

  1. First Year Seminar A

    2021

  2. Biochemical Engineeing

    2021

  3. Advanced Experiments and Exercises in Biosystem Engineering 1

    2021

  4. Advanced Experiments and Exercises in Biosystem Engineering 2

    2021

  5. Advanced Experiments and Exercises in Biosystem Engineering 3

    2021

  6. Advanced Experiments and Exercises in Biosystem Engineering 3

    2021

  7. Seminar on Biosystem Engineering 2A

    2021

  8. Seminar on Biosystem Engineering 2B

    2021

  9. Seminar on Biosystem Engineering 2C

    2021

  10. Seminar on Biosystem Engineering 2D

    2021

  11. Seminar on Biosystem Engineering 2E

    2021

  12. Seminar on Biosystem Engineering 1D

    2021

  13. Biotechnology Exercises 1

    2021

  14. Fundamentals of Chemical Engineering

    2021

  15. Fundamentals of Chemical Engineering

    2021

  16. Biochemistry 4 with Exercises

    2021

  17. Seminar on Biosystem Engineering 1A

    2021

  18. Seminar on Biosystem Engineering 1B

    2021

  19. Seminar on Biosystem Engineering 1C

    2021

  20. 生物機能工学演習1

    2018

  21. 生物化学工学

    2018

  22. 化学工学基礎

    2018

  23. 基礎セミナーA

    2018

  24. 基礎セミナーA

    2017

  25. 生物化学工学

    2017

  26. 生物機能工学演習1

    2017

  27. 生物機能工学演習2

    2016

  28. 生物化学序論

    2016

  29. 生物プロセス工学

    2016

  30. 化学工学基礎

    2016

  31. 生物機能工学演習1

    2016

  32. 生物化学工学

    2016

  33. 基礎セミナーA

    2016

  34. 生物機能工学演習1

    2015

  35. 生物化学序論

    2015

  36. 生物化学工学

    2015

  37. 生物プロセス工学

    2015

  38. 基礎セミナーA

    2015

  39. 生物機能工学演習1

    2014

  40. 生物化学序論

    2014

  41. 生物化学工学

    2014

  42. 生物プロセス工学

    2014

  43. 基礎セミナーA

    2014

  44. 生物化学工学

    2013

  45. 生物機能工学演習1

    2013

  46. 生物化学序論

    2013

  47. 生物プロセス工学

    2013

  48. 基礎セミナーA

    2013

  49. 生物プロセス工学

    2012

  50. 生物化学序論

    2012

  51. First Year Seminar A

    2012

  52. First Year Seminar A

    2011

  53. 生物化学工学

    2009

  54. バイオテクノロジー基礎論

    2009

  55. 生物化学序論

    2009

  56. 基礎セミナーA

    2008

  57. バイオテクノロイジー基礎論

    2008

  58. バイオテクノロジーセミナー1A

    2008

  59. バイオテクノロジーセミナー1C

    2008

  60. 生物機能工学演習Ⅰ

    2008

  61. 生物化学工学

    2008

  62. 生物化学工学

    2007

  63. 生物化学序論

    2007

  64. 生物プロセス工学

    2007

  65. 基礎セミナー

    2007

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Teaching Experience (Off-campus) 6

  1. 化学工学

    2009.4 - 2010.3 名城大学)

  2. 2007.4 - 2008.3 名古屋大学医学部)

  3. 2006.4 - 2007.3 名古屋大学医学部)

  4. 2005.4 - 2006.3 新潟大学工学部)

  5. 2005.4 - 2006.3 名古屋大学医学部)

  6. 2005.4 - 2006.3 静岡大学農学部)

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