論文 - 大橋　浩二

Adipolin/CTRP12 protects against pathological vascular remodelling through suppression of smooth muscle cell growth and macrophage inflammatory response 査読有り

Ogawa Hayato, Ohashi Koji, Ito Masanori, Shibata Rei, Kanemura Noriyoshi, Yuasa Daisuke, Kambara Takahiro, Matsuo Kazuhiro, Hayakawa Satoko, Hiramatsu-Ito Mizuho, Otaka Naoya, Kawanishi Hiroshi, Yamaguchi Shukuro, Enomoto Takashi, Abe Takaya, Kaneko Mari, Takefuji Mikito, Murohara Toyoaki, Ouchi Noriyuki

CARDIOVASCULAR RESEARCH   116 巻 ( 1 ) 頁： 237 - 249   2020年1月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1093/cvr/cvz074

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PubMed

その他リンク： http://academic.oup.com/cardiovascres/article-pdf/116/1/237/31555893/cvz074.pdf

Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin 査読有り

Sakaguchi Teruhiro, Takefuji Mikito, Wettschureck Nina, Hamaguchi Tomonari, Amano Mutsuki, Kato Katsuhiro, Tsuda Takuma, Eguchi Shunsuke, Ishihama Sohta, Mori Yu, Yura Yoshimitsu, Yoshida Tatsuya, Unno Kazumasa, Okumura Takahiro, Ishii Hideki, Shimizu Yuuki, Bando Yasuko K., Ohashi Koji, Ouchi Noriyuki, Enomoto Atsushi, Offermanns Stefan, Kaibuchi Kozo, Murohara Toyoaki

CIRCULATION   140 巻 ( 21 ) 頁： 1737 - 1752   2019年11月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1161/CIRCULATIONAHA.119.041019

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Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction 査読有り

Eguchi Shunsuke, Takefuji Mikito, Sakaguchi Teruhiro, Ishihama Sohta, Mori Yu, Tsuda Takuma, Takikawa Tomonobu, Yoshida Tatsuya, Ohashi Koji, Shimizu Yuuki, Hayashida Ryo, Kondo Kazuhisa, Bando Yasuko K., Ouchi Noriyuki, Murohara Toyoaki

JOURNAL OF BIOLOGICAL CHEMISTRY   294 巻 ( 31 ) 頁： 11665 - 11674   2019年8月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1074/jbc.RA119.007537

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Associations among circulating levels of follistatin-like 1, clinical parameters, and cardiovascular events in patients undergoing elective percutaneous coronary intervention with drug-eluting stents 査読有り

Aikawa Tatsuro, Shimada Kazunori, Miyauchi Katsumi, Miyazaki Tetsuro, Sai Eiryu, Ouchi Shohei, Kadoguchi Tomoyasu, Kunimoto Mitsuhiro, Joki Yusuke, Dohi Tomotaka, Okazaki Shinya, Isoda Kikuo, Ohashi Koji, Murohara Toyoaki, Ouchi Noriyuki, Daida Hiroyuki

PLOS ONE   14 巻 ( 4 ) 頁： e0216297   2019年4月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1371/journal.pone.0216297

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Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury 査読有り

Otaka Naoya, Shibata Rei, Ohashi Koji, Uemura Yusuke, Kambara Takahiro, Enomoto Takashi, Ogawa Hayato, Ito Masanori, Kawanishi Hiroshi, Maruyama Sonomi, Joki Yusuke, Fujikawa Yusuke, Narita Shingo, Unno Kazumasa, Kawamoto Yoshiyuki, Murate Takashi, Murohara Toyoaki, Ouchi Noriyuki

CIRCULATION RESEARCH   123 巻 ( 12 ) 頁： 1326-1338   2018年12月

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1161/CIRCRESAHA.118.313777

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Role of Adipokines in Cardiovascular Disease 査読有り

Lau Wayne Bond, Ohashi Koji, Wang Yajing, Ogawa Hayato, Murohara Toyoaki, Ma Xin-Liang, Ouchi Noriyuki

CIRCULATION JOURNAL   81 巻 ( 7 ) 頁： 920-928   2017年7月

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1253/circj.CJ-17-0458

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C1q/TNF-related protein 1 prevents neointimal formation after arterial injury 査読有り

Kanemura Noriyoshi, Shibata Rei, Ohashi Koji, Ogawa Hayato, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Ito Masanori, Hayakawa Satoko, Otaka Naoya, Murohara Toyoaki, Ouchi Noriyuki

ATHEROSCLEROSIS   257 巻   頁： 138-145   2017年2月

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.atherosclerosis.2017.01.014

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The role of adipokines in cardiovascular disease 査読有り

Shibata Rei, Ouchi Noriyuki, Ohashi Koji, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   70 巻 ( 3-4 ) 頁： 329-334   2017年

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記述言語：英語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.jjcc.2017.02.006

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Protective Roles of Adipocytokines and Myokines in Cardiovascular Disease 査読有り

Ouchi Noriyuki, Ohashi Koji, Shibata Rei, Murohara Toyoaki

CIRCULATION JOURNAL   80 巻 ( 10 ) 頁： 2073 - 2080   2016年10月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1253/circj.CJ-16-0663

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Association of Circulating Follistatin-Like 1 Levels with Inflammatory and Oxidative Stress Markers in Healthy Men 査読有り

Hayakawa Satoko, Ohashi Koji, Shibata Rei, Takahashi Ryotaro, Otaka Naoya, Ogawa Hayato, Ito Masanori, Kanemura Noriyoshi, Hiramatsu-Ito Mizuho, Ikeda Nobuo, Murohara Toyoaki, Ouchi Noriyuki

PLOS ONE   11 巻 ( 5 ) 頁： e0153619   2016年5月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1371/journal.pone.0153619

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Omentin attenuates atherosclerotic lesion formation in apolipoprotein E-deficient mice 査読有り

Hiramatsu-Ito Mizuho, Shibata Rei, Ohashi Koji, Uemura Yusuke, Kanemura Noriyoshi, Kambara Takahiro, Enomoto Takashi, Yuasa Daisuke, Matsuo Kazuhiro, Ito Masanori, Hayakawa Satoko, Ogawa Hayato, Otaka Naoya, Kihara Shinji, Murohara Toyoaki, Ouchi Noriyuki

CARDIOVASCULAR RESEARCH   110 巻 ( 1 ) 頁： 107 - 117   2016年5月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1093/cvr/cvv282

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C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart 査読有り

Yuasa Daisuke, Ohashi Koji, Shibata Rei, Mizutani Naoki, Kataoka Yoshiyuki, Kambara Takahiro, Uemura Yusuke, Matsuo Kazuhiro, Kanemura Noriyoshi, Hayakawa Satoko, Hiramatsu-Ito Mizuho, Ito Masanori, Ogawa Hayato, Murate Takashi, Murohara Toyoaki, Ouchi Noriyuki

FASEB JOURNAL   30 巻 ( 3 ) 頁： 1065 - 1075   2016年3月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1096/fj.15-279885

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Role of a novel secreted factor omentin in cardiovascular disease 査読有り

Ouchi Noriyuki, Ohashi Koji, Shibata Rei, Murohara Toyoaki

JOURNAL OF PHARMACOLOGICAL SCIENCES   128 巻 ( 3 ) 頁： S35 - S35   2015年7月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

Web of Science

C1q/Tumor Necrosis Factor-Related Protein 9 Protects against Acute Myocardial Injury through an Adiponectin Receptor I-AMPK-Dependent Mechanism 査読有り

Kambara Takahiro, Shibata Rei, Ohashi Koji, Matsuo Kazuhiro, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Ito Masanori, Hayakawa Satoko, Ogawa Hayato, Aprahamian Tamar, Walsh Kenneth, Murohara Toyoaki, Ouchi Noriyuki

MOLECULAR AND CELLULAR BIOLOGY   35 巻 ( 12 ) 頁： 2173 - 2185   2015年6月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1128/MCB.01518-14

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FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism 査読有り

Joki Yusuke, Ohashi Koji, Yuasa Daisuke, Shibata Rei, Ito Masanori, Matsuo Kazuhiro, Kambara Takahiro, Uemura Yusuke, Hayakawa Satoko, Hiramatsu-Ito Mizuho, Kanemura Noriyoshi, Ogawa Hayato, Daida Hiroyuki, Murohara Toyoaki, Ouchi Noriyuki

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   459 巻 ( 1 ) 頁： 124 - 130   2015年3月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.bbrc.2015.02.081

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Neuron-Derived Neurotrophic Factor Ameliorates Adverse Cardiac Remodeling After Experimental Myocardial Infarction. 査読有り

Joki Y, Ohashi K, Yuasa D, Shibata R, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ito M, Ogawa H, Daida H, Murohara T, Ouchi N.

Circulation: Heart Failure     頁： in press   2015年2月

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担当区分：筆頭著者   記述言語：英語   掲載種別：研究論文（学術雑誌）  

Omentin functions to attenuate cardiac hypertrophic response 査読有り

Matsuo Kazuhiro, Shibata Rei, Ohashi Koji, Kambara Takahiro, Uemura Yusuke, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Joki Yusuke, Ito Masanori, Hayakawa Satoko, Ogawa Hayato, Kihara Shinji, Murohara Toyoaki, Ouchi Noriyuki

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY   79 巻   頁： 195 - 202   2015年2月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.yjmcc.2014.11.019

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Adipose-derived protein omentin prevents neointimal formation after arterial injury 査読有り

Uemura Yusuke, Shibata Rei, Kanemura Noriyoshi, Ohashi Koji, Kambara Takahiro, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Joki Yusuke, Matsuo Kazuhiro, Ito Masanori, Hayakawa Satoko, Ogawa Hayato, Murohara Toyoaki, Ouchi Noriyuki

FASEB JOURNAL   29 巻 ( 1 ) 頁： 141 - 151   2015年1月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1096/fj.14-258129

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PubMed

Adiponectin as a Target in Obesity-related Inflammatory State 査読有り

Koji Ohashi, Daisuke Yuasa, Rei Shibata, Toyoaki Murohara, Noriyuki Ouchi

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS   15 巻 ( 2 ) 頁： 145 - 150   2015年

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記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：BENTHAM SCIENCE PUBL LTD  

Accumulating evidence indicates that low grade inflammation is closely associated with obesity-related disorders including type 2 diabetes, hypertension and atherosclerosis. Adiponectin is a fat-derived plasma protein with anti-inflammatory functions. Circulating levels of adiponectin are decreased in obese states, and these conditions are broadly associated with various obesity-related diseases. Furthermore, adiponectin has direct protective functions against cardiovascular disease, cerebrovascular disease, non-alcoholic steatohepatitis (NASH) and chronic kidney disease (CKD). In this review, we will focus on the protective functions of adiponectin against these obesity-related diseases from the view point of its anti-inflammatory properties.

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The potential of adipokines as therapeutic agents for cardiovascular disease 査読有り

Shibata Rei, Ohashi Koji, Murohara Toyoaki, Ouchi Noriyuki

CYTOKINE & GROWTH FACTOR REVIEWS   25 巻 ( 4 ) 頁： 483 - 487   2014年8月

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記述言語：日本語   掲載種別：研究論文（学術雑誌）  

DOI： 10.1016/j.cytogfr.2014.07.005

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