日本糖尿病学会

Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study

Kurasawa, S; Kato, S; Ozeki, T; Akiyama, S; Ishimoto, T; Mizuno, M; Tsuboi, N; Kato, N; Kosugi, T; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY     2024年1月

Renal pathology in adult and paediatric population of Japan: review of the Japan renal biopsy registry database from 2007 to 2017

Goto, K; Imaizumi, T; Hamada, R; Ishikura, K; Kosugi, T; Narita, I; Sugiyama, H; Shimizu, A; Yokoyama, H; Sato, H; Mauryama, S

JOURNAL OF NEPHROLOGY   36 巻 ( 8 ) 頁： 2257 - 2267   2023年11月

Basigin is released in extracellular vesicles derived from the renal tubular epithelium in response to albuminuria

Watanabe, T; Maeda, K; Kato, N; Seko, H; Sugimura, M; Sato, Y; Ryuge, A; Kato, S; Kadomatsu, K; Maruyama, S; Kosugi, T

NEPHROLOGY   28 巻 ( 11 ) 頁： 629 - 638   2023年11月

Fructose might be a clue to the origin of preeclampsia insights from nature and evolution

Nakagawa Takahiko, Andres-Hernando Ana, Kosugi Tomoki G., Sanchez-Lozada Laura, Stenvinkel Peter, Kublickiene Karolina, Karumanchi S. Ananth, Kang Duk-Hee, Kojima Hideto, Rodriguez-Iturbe Bernardo R., Tolan Dean A., Lanaspa Miguel J., Johnson Richard

HYPERTENSION RESEARCH   46 巻 ( 3 ) 頁： 646 - 653   2023年3月

IgA-dominant glomerulonephritis with DNAJB9-negative fibrillar polytypic immunoglobulin deposits in the subepithelium

Muto Reiko, Maeda Kayaho, Fukui Sosuke, Saito Shoji, Kato Noritoshi, Kosugi Tomoki, Shimizu Akira, Maruyama Shoichi

CEN CASE REPORTS     2022年12月

Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis

Kitai Hiroki, Kato Noritoshi, Ogami Koichi, Komatsu Shintaro, Watanabe Yu, Yoshino Seiko, Koshi Eri, Tsubota Shoma, Funahashi Yoshio, Maeda Takahiro, Furuhashi Kazuhiro, Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi, Kadomatsu Kenji, Suzuki Hiroshi I

BMC BIOLOGY   20 巻 ( 1 ) 頁： 248   2022年11月

Increased Monocyte/Lymphocyte Ratio as Risk Marker for Cardiovascular Events and Infectious Disease Hospitalization in Dialysis Patients

Muto Reiko, Kato Sawako, Lindholm Bengt, Qureshi Abdul Rashid, Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi

BLOOD PURIFICATION   51 巻 ( 9 ) 頁： 747 - 755   2022年9月

Protocol for a Phase 1, Open-Label, Multiple-Center, Dose-Escalation Study to Evaluate the Safety and Tolerability of ADR-001 in the Treatment of Immunoglobulin A Nephropathy

Tanaka Akihito, Furuhashi Kazuhiro, Fujieda Kumiko, Maeda Kayaho, Saito Shoji, Mimura Tetsushi, Saka Yosuke, Naruse Tomohiko, Ishimoto Takuji, Kosugi Tomoki, Kinoshita Fumie, Kuwatsuka Yachiyo, Shimizu Shinobu, Nakai Yasuhiro, Maruyama Shoichi

FRONTIERS IN MEDICINE   9 巻   頁： 883168   2022年5月

Sex differences in clinical outcomes in Japanese incident dialysis patients: a prospective observational multicenter study

Kozaki Yohei, Morinaga Takatoshi, Fukatsu Atsushi, Ito Takeshi, Ishimoto Takuji, Kosugi Tomoki, Inaguma Daijo, Tamai Hirofumi, Maruyama Shoichi

CLINICAL AND EXPERIMENTAL NEPHROLOGY   26 巻 ( 5 ) 頁： 466 - 475   2022年5月

Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis

Ryuge Akihiro, Kosugi Tomoki, Maeda Kayaho, Banno Ryoichi, Gou Yang, Zaitsu Kei, Ito Takanori, Sato Yuka, Hirayama Akiyoshi, Tsubota Shoma, Honda Takashi, Nakajima Kazuki, Ozaki Tomoya, Kondoh Kunio, Takahashi Kazuo, Kato Noritoshi, Ishimoto Takuji, Soga Tomoyoshi, Nakagawa Takahiko, Koike Teruhiko, Arima Hiroshi, Yuzawa Yukio, Minokoshi Yasuhiko, Maruyama Shoichi, Kadomatsu Kenji

JCI INSIGHT   6 巻 ( 20 )   2021年10月

Efficacy of favipiravir for an end stage renal disease patient on maintenance hemodialysis infected with novel coronavirus disease 2019

Koshi Eri, Saito Shoji, Okazaki Masaki, Toyama Yuki, Ishimoto Takuji, Kosugi Tomoki, Hiraiwa Hiroaki, Jingushi Naruhiro, Yamamoto Takanori, Ozaki Masayuki, Goto Yukari, Numaguchi Atsushi, Miyagawa Yasuhiro, Kato Io, Tetsuka Nobuyuki, Yagi Tetsuya, Maruyama Shoichi

CEN CASE REPORTS   10 巻 ( 1 ) 頁： 126 - 131   2021年2月

The ISN/RPS 2016 classification predicts renal prognosis in patients with first-onset class III/IV lupus nephritis

Hachiya Asaka, Karasawa Munetoshi, Imaizumi Takahiro, Kato Noritoshi, Katsuno Takayuki, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Maruyama Shoichi

SCIENTIFIC REPORTS   11 巻 ( 1 ) 頁： 1525   2021年1月

Refractory Hypotension Caused by Selenium Deficiency in a Patient on Peritoneal Dialysis

Ryuge Akihiro, Kim Hangsoo, Suzuki Yasuhiro, Okazaki Masaki, Kojima Hiroshi, Saito Shoji, Kato Noritoshi, Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi, Mizuno Masashi

INTERNAL MEDICINE   60 巻 ( 15 ) 頁： 2461 - 2464   2021年

Acquired Fanconi Syndrome in a Patient with Nontyphoidal Salmonella Bacteremia

Ryuge Akihiro, Saito Shoji, Morioka Hiroshi, Hachiya Asaka, Kato Noritoshi, Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi

INTERNAL MEDICINE   60 巻 ( 5 ) 頁： 761 - 764   2021年

A Prospective, Randomized Clinical Trial of Etelcalcetide in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism (the DUET Trial)

Itano Yuya, Kato Sawako, Tsuboi Masato, Kasuga Hirotake, Tsuruta Yoshinari, Sato Fumihiko, Hishida Manabu, Ishimoto Takuji, Kosugi Tomoki, Ando Masahiko, Kuwatsuka Yachiyo, Maruyama Shoichi

KIDNEY INTERNATIONAL REPORTS   5 巻 ( 12 ) 頁： 2168 - 2177   2020年12月

ANALYSIS OF FREQUENCY AND KINDS OF ALARM HISTORIES OF HOME PD SYSTEM KAGUYA DURING THE INTRODUCTION: PERIOD IN A SINGLE CENTRE

Hiramatsu Tetsuaki, Mizuno Masasi, Suzuki Yasuhiro, Nomori Sumiyo, Suzuki Masafumi, Shiga Yoshiko, Sato Yuka, Nakamura Tomohiro, Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi, Koyama Tomio

NEPHROLOGY   25 巻   頁： 77 - 78   2020年10月

Guideline on the use of iodinated contrast media in patients with kidney disease 2018

Isaka Yoshitaka, Hayashi Hiromitsu, Aonuma Kazutaka, Horio Masaru, Terada Yoshio, Doi Kent, Fujigaki Yoshihide, Yasuda Hideo, Sato Taichi, Fujikura Tomoyuki, Kuwatsuru Ryohei, Toei Hiroshi, Murakami Ryusuke, Saito Yoshihiko, Hirayama Atsushi, Murohara Toyoaki, Sato Akira, Ishii Hideki, Takayama Tadateru, Watanabe Makoto, Awai Kazuo, Oda Seitaro, Murakami Takamichi, Yagyu Yukinobu, Joki Nobuhiko, Komatsu Yasuhiro, Miyauchi Takamasa, Ito Yugo, Miyazawa Ryo, Kanno Yoshihiko, Ogawa Tomonari, Hayashi Hiroki, Koshi Eri, Kosugi Tomoki, Yasuda Yoshinari, Isaka Yoshitaka, Horio Masaru, Terada Yoshio, Doi Kent, Fujigaki Yoshihide, Yasuda Hideo, Sato Taichi, Fujikura Tomoyuki, Joki Nobuhiko, Komatsu Yasuhiro, Miyauchi Takamasa, Ito Yugo, Kanno Yoshihiko, Ogawa Tomonari, Hayashi Hiroki, Koshi Eri, Kosugi Tomoki, Yasuda Yoshinari, Hayashi Hiromitsu, Kuwatsuru Ryohei, Toei Hiroshi, Murakami Ryusuke, Awai Kazuo, Oda Seitaro, Murakami Takamichi, Yagyu Yukinobu, Miyazawa Ryo, Aonuma Kazutaka, Saito Yoshihiko, Watanabe Makoto, Hirayama Atsushi, Murohara Toyoaki, Sato Akira, Ishii Hideki, Takayama Tadateru

CLINICAL AND EXPERIMENTAL NEPHROLOGY   24 巻 ( 1 ) 頁： 1 - 44   2020年1月

Guideline on the use of iodinated contrast media in patients with kidney disease 2018

Isaka Yoshitaka, Hayashi Hiromitsu, Aonuma Kazutaka, Horio Masaru, Terada Yoshio, Doi Kent, Fujigaki Yoshihide, Yasuda Hideo, Sato Taichi, Fujikura Tomoyuki, Kuwatsuru Ryohei, Toei Hiroshi, Murakami Ryusuke, Saito Yoshihiko, Hirayama Atsushi, Murohara Toyoaki, Sato Akira, Ishii Hideki, Takayama Tadateru, Watanabe Makoto, Awai Kazuo, Oda Seitaro, Murakami Takamichi, Yagyu Yukinobu, Joki Nobuhiko, Komatsu Yasuhiro, Miyauchi Takamasa, Ito Yugo, Miyazawa Ryo, Kanno Yoshihiko, Ogawa Tomonari, Hayashi Hiroki, Koshi Eri, Kosugi Tomoki, Yasuda Yoshinari, Miyauchi Takamasa, Ito Yugo, Kanno Yoshihiko, Ogawa Tomonari, Hayashi Hiroki, Koshi Eri

JAPANESE JOURNAL OF RADIOLOGY   38 巻 ( 1 ) 頁： 3 - 46   2020年1月

Successful Introduction of Peritoneal Dialysis in an End-stage Renal Failure Patient with Idiopathic Aplastic Anemia

Suzuki Yasuhiro, Mizuno Masashi, Sakata Fumiko, Kojima Hiroshi, Sato Yuka, Kishimoto Mayuko, Suzuki Nobuaki, Kinashi Hiroshi, Saito Shoji, Katsuno Takayuki, Kosugi Tomoki, Maruyama Shoichi, Murata Makoto, Kiyoi Hitoshi, Ito Yasuhiko

INTERNAL MEDICINE   59 巻 ( 5 ) 頁： 683-687   2020年

Guideline on the Use of Iodinated Contrast Media in Patients With Kidney Disease 2018

Isaka Yoshitaka, Hayashi Hiromitsu, Aonuma Kazutaka, Horio Masaru, Terada Yoshio, Doi Kent, Fujigaki Yoshihide, Yasuda Hideo, Sato Taichi, Fujikura Tomoyuki, Kuwatsuru Ryohei, Toei Hiroshi, Murakami Ryusuke, Saito Yoshihiko, Hirayama Atsushi, Murohara Toyoaki, Sato Akira, Ishii Hideki, Takayama Tadateru, Watanabe Makoto, Awai Kazuo, Oda Seitaro, Murakami Takamichi, Yagyu Yukinobu, Joki Nobuhiko, Komatsu Yasuhiro, Miyauchi Takamasa, Ito Yugo, Miyazawa Ryo, Kanno Yoshihiko, Ogawa Tomonari, Hayashi Hiroki, Koshi Eri, Kosugi Tomoki, Yasuda Yoshinari

CIRCULATION JOURNAL   83 巻 ( 12 ) 頁： 2572 - 2607   2019年12月

Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure

Sato Yuka, Roncal-Jimenez Carlos A., Andres-Hernando Ana, Jensen Thomas, Tolan Dean R., Sanchez-Lozada Laura G., Newman Lee S., Butler-Dawson Jaime, Sorensen Cecilia, Glaser Jason, Miyazaki Makoto, Diaz Henry F., Ishimoto Takuji, Kosugi Tomoki, Maruyama Shoichi, Garcia Gabriela E., Lanaspa Miguel A., Johnson Richard J.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY   317 巻 ( 5 ) 頁： F1111-F1121   2019年11月

Circulating levels of CD34(+) cells predict longterm cardiovascular outcomes in patients on maintenance hemodialysis

Kaihan Ahmad Baseer, Hishida Manabu, Imaizumi Takahiro, Okazaki Masaki, Kaihan Ahmad Naseer, Katsuno Takayuki, Taguchi Akihiko, Yasuda Yoshinari, Tsuboi Naotake, Kosugi Tomoki, Maruyama Shoichi

PLOS ONE   14 巻 ( 10 ) 頁： e0223390   2019年10月

Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase

Hayasaki Takahiro, Ishimoto Takuji, Doke Tomohito, Hirayama Akiyoshi, Soga Tomoyoshi, Furuhashi Kazuhiro, Kato Noritoshi, Kosugi Tomoki, Tsuboi Naotake, Lanaspa Miguel A., Johnson Richard J., Maruyama Shoichi, Kadomatsu Kenji

JOURNAL OF NUTRITIONAL BIOCHEMISTRY   71 巻   頁： 54-62   2019年9月

The effect of maintaining high hemoglobin levels on long-term kidney function in kidney transplant recipients: a randomized controlled trial 査読有り

Tsujita Makoto, Kosugi Tomoki, Goto Norihiko, Futamura Kenta, Nishihira Morikuni, Okada Manabu, Hiramitsu Takahisa, Narumi Shunji, Uchida Kazuharu, Takeda Asami, Morozumi Kunio, Maruyama Shoichi, Watarai Yoshihiko

NEPHROLOGY DIALYSIS TRANSPLANTATION   34 巻 ( 8 ) 頁： 1409 - 1416   2019年8月

miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury 査読有り

Funahashi Yoshio, Kato Noritoshi, Masuda Tomohiro, Nishio Fumitoshi, Kitai Hiroki, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Matsuda Naoyuki, Maruyama Shoichi, Kadomatsu Kenji

LABORATORY INVESTIGATION   99 巻 ( 8 ) 頁： 1130 - 1142   2019年8月

CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling

Yoshioka Tomoki, Kosugi Tomoki, Masuda Tomohiro, Watanabe Tomoharu, Ryuge Akihiro, Nagaya Hiroshi, Maeda Kayaho, Sato Yuka, Katsuno Takayuki, Kato Noritoshi, Ishimoto Takuji, Yuzawa Yukio, Maruyama Shoichi, Kadomatsu Kenji

AMERICAN JOURNAL OF PATHOLOGY   189 巻 ( 7 ) 頁： 1338-1350   2019年7月

Therapeutic efficacy of rituximab for the management of adult-onset steroid-dependent nephrotic syndrome: a retrospective study 査読有り

Katsuno Takayuki, Masuda Tomohiro, Saito Shoji, Kato Noritoshi, Ishimoto Takuji, Kato Sawako, Kosugi Tomoki, Tsuboi Naotake, Kitamura Hiroshi, Tsuzuki Toyonori, Ito Yasuhiko, Maruyama Shoichi

CLINICAL AND EXPERIMENTAL NEPHROLOGY   23 巻 ( 2 ) 頁： 207 - 214   2019年2月

The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity 査読有り

Kameyama Hirokazu, Uchimura Kenji, Yamashita Taro, Kuwabara Kaori, Mizuguchi Mineyuki, Hung Shang-Cheng, Okuhira Keiichiro, Masuda Tomohiro, Kosugi Tomoki, Ohgita Takashi, Saito Hiroyuki, Ando Yukio, Nishitsuji Kazuchika

AMERICAN JOURNAL OF PATHOLOGY   189 巻 ( 2 ) 頁： 308 - 319   2019年2月

Investigation on the benefits of mycophenolate mofetil and therapeutic drug monitoring in the treatment of Japanese patients with lupus nephritis 査読有り

Katsuno Takayuki, Ozaki Takenori, Ozeki Takaya, Hachiya Asaka, Kim Hangsoo, Kato Noritoshi, Ishimoto Takuji, Kato Sawako, Kosugi Tomoki, Tsuboi Naotake, Mizuno Masashi, Ito Yasuhiko, Maruyama Shoichi

CLINICAL AND EXPERIMENTAL NEPHROLOGY   22 巻 ( 6 ) 頁： 1341 - 1350   2018年12月

Serum alpha cKlotho as a Predictor of Graft Dysfunction After Kidney Transplantation

Tsujita M., Kosugi T., Masuda T., Okada M., Futamura K., Hiramitsu T., Goto N., Shunji N., Watarai Y., Maruyama S.

TRANSPLANTATION PROCEEDINGS   50 巻 ( 10 ) 頁： 3440 - 3444   2018年12月

The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases

Mori Yoshiko, Masuda Tomohiro, Kosugi Tomoki, Yoshioka Tomoki, Hori Mayuko, Nagaya Hiroshi, Maeda Kayaho, Sato Yuka, Kojima Hiroshi, Kato Noritoshi, Ishimoto Takuji, Katsuno Takayuki, Yuzawa Yukio, Kadomatsu Kenji, Maruyama Shoichi

CLINICAL AND EXPERIMENTAL NEPHROLOGY   22 巻 ( 4 ) 頁： 815 - 824   2018年8月

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice 査読有り

Doke Tomohito, Ishimoto Takuji, Hayasaki Takahiro, Ikeda Satsuki, Hasebe Masako, Hirayama Akiyoshi, Soga Tomoyoshi, Kato Noritoshi, Kosugi Tomoki, Tsuboi Naotake, Lanaspa Miguel A., Johnson Richard J., Kadomatsu Kenji, Maruyama Shoichi

METABOLISM-CLINICAL AND EXPERIMENTAL   85 巻   頁： 161 - 170   2018年8月

Efficacy of urinary midkine as a biomarker in patients with acute kidney injury

Hayashi Hiroki, Sato Waichi, Kosugi Tomoki, Nishimura Kunihiro, Sugiyama Daisuke, Asano Naoko, Ikematsu Shinya, Komori Kimihiro, Nishiwaki Kimitoshi, Kadomatsu Kenji, Matsuo Seiichi, Maruyama Shoichi, Yuzawa Yukio

CLINICAL AND EXPERIMENTAL NEPHROLOGY   21 巻 ( 4 ) 頁： 597-607   2017年8月

Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis

Masuda Tomohiro, Maeda Kayaho, Sato Waichi, Kosugi Tomoki, Sato Yuka, Kojima Hiroshi, Kato Noritoshi, Ishimoto Takuji, Tsuboi Naotake, Uchimura Kenji, Yuzawa Yukio, Maruyama Shoichi, Kadomatsu Kenji

AMERICAN JOURNAL OF PATHOLOGY   187 巻 ( 4 ) 頁： 740-751   2017年4月

A CASE OF RAPIDLY PROGRESSIVE NEPHRITIC SYNDROME AND NEPHROTIC SYNDROME DURING THE TREATMENT OF DERMATOMYOSITIS AND DIABETES

Sato, N; Katsuno, T; Mori, M; Saito, S; Kato, N; Ishimoto, T; Kosugi, T; Tsuboi, N; Ito, Y; Maruyama, S

RHEUMATOLOGY   56 巻   頁： 75 - 75   2017年3月

Single-dose Rituximab Therapy for Refractory Idiopathic Membranous Nephropathy: A Single-center Experience

Katsuno Takayuki, Ozaki Takenori, Kim Hangsoo, Kato Noritoshi, Suzuki Yasuhiro, Akiyama Shinichi, Ishimoto Takuji, Kosugi Tomoki, Tsuboi Naotake, Ito Yasuhiko, Maruyama Shoichi

INTERNAL MEDICINE   56 巻 ( 13 ) 頁： 1679-1686   2017年

Urinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis. 査読有り

Endo N, Tsuboi N, Furuhashi K, Shi Y, Du Q, Abe T, Hori M, Imaizumi T, Kim H, Katsuno T, Ozaki T, Kosugi T, Matsuo S, Maruyama S.

Nephrol Dial Transplant.   31 巻 ( 12 ) 頁： 2023-2033   2016年12月

Randomized control trial for the assessment of the anti-albuminuric effects of topiroxostat in hyperuricemic patients with diabetic nephropathy (the ETUDE study). 査読有り

Kato S, Ando M, Mizukoshi T, Nagata T, Katsuno T, Kosugi T, Tsuboi N, Maruyama S.

Nagoya J Med Sci.   78 巻 ( 2 ) 頁： 135-142   2016年5月

Efficacy of urinary midkine as a biomarker in patients with acute kidney injury. 査読有り

Hayashi H, Sato W, Kosugi T, Nishimura K, Sugiyama D, Asano N, Ikematsu S, Komori K, Nishiwaki K, Kadomatsu K, Matsuo S, Maruyama S, Yuzawa Y.

Clin Exp Nephrol.     2016年

Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury. 査読有り

Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S.

PLoS One.   10 巻 ( 10 ) 頁： e0140121   2015年10月

Fructose and uric acid in diabetic nephropathy. 招待有り 査読有り

Bjornstad P, Lanaspa MA, Ishimoto T, Kosugi T, Kume S, Jalal D, Maahs DM, Snell-Bergeon JK, Johnson RJ, Nakagawa T.

Diabetologia.   58 巻 ( 9 ) 頁： 1993-2002   2015年9月

Increase of Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody (ANCA) in Patients with Renal ANCA-associated Vasculitis: Association with Risk to Relapse. 査読有り

Yamaguchi M, Ando M, Kato S, Katsuno T, Kato N, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

J Rheumatol.     2015年9月

Neutrophil/lymphocyte ratio as a predictor of cardiovascular events in incident dialysis patients: a Japanese prospective cohort study. 査読有り

Abe T, Kato S, Tsuruta Y, Sugiura S, Katsuno T, Kosugi T, Tsuboi N, Matsuo S, Maruyama S.

Clin Exp Nephrol.   19 巻 ( 4 ) 頁： 718-724   2015年8月

The efficacy of tolvaptan as a diuretic for chronic kidney disease patients. 査読有り

Tanaka A, Katsuno T, Ozaki T, Sakata F, Kato N, Suzuki Y, Kosugi T, Kato S, Tsuboi N, Sato W, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

Acta Cardiol.   70 巻 ( 2 ) 頁： 217-223   2015年4月

CD147/Basigin limits lupus nephritis and TH 17 cell differentiation by inhibiting the IL-6/STAT3 pathway. 査読有り

Maeda K, Kosugi T, Sato W, Kojima H, Sato Y, Kamimura D, Kato N, Tsuboi N, Yuzawa Y, Matsuo S, Murakami M, Maruyama S, Kadomatsu K.

Arthritis Rheumatol.     2015年

Midkine Regulates BP through Cytochrome P450-Derived Eicosanoids. 査読有り

Sato Y, Sato W, Maruyama S, Wilcox CS, Falck JR, Masuda T, Kosugi T, Kojima H, Maeda K, Furuhashi K, Ando M, Imai E, Matsuo S, Kadomatsu K.

J Am Soc Nephrol.     2015年

Comparison of kidney disease: improving global outcomes and acute kidney injury network criteria for assessing patients in intensive care units. 査読有り

Shinjo H, Sato W, Imai E, Kosugi T, Hayashi H, Nishimura K, Nishiwaki K, Yuzawa Y, Matsuo S, Maruyama S.

Clin Exp Nephrol.   18 巻 ( 5 ) 頁： 737-45   2014年10月

Patient age and the prognosis of idiopathic membranous nephropathy. 査読有り

Yamaguchi M, Ando M, Yamamoto R, Akiyama S, Kato S, Katsuno T, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

PLoS One   9 巻 ( 10 ) 頁： e110376   2014年8月

Smoking is a risk factor for the progression of idiopathic membranous nephropathy. 査読有り

Yamaguchi M, Ando M, Yamamoto R, Akiyama S, Kato S, Katsuno T, Kosugi T, Sato W, Tsuboi N, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

PLoS One   9 巻 ( 6 ) 頁： e100835   2014年6月

Pristane-Induced Granulocyte Recruitment Promotes Phenotypic Conversion of Macrophages and Protects Against Diffuse Pulmonary Hemorrhage in Mac-1 Deficiency. 査読有り

Shi Y, Tsuboi N, Furuhashi K, Du Q, Horinouchi A, Maeda K, Kosugi T, Matsuo S, Maruyama S.

J Immunol     2014年

CD147 (EMMPRIN/Basigin) in kidney diseases: from an inflammation and immune system viewpoint. 招待有り 査読有り

Kosugi T, Maeda K, Sato W, Maruyama S, Kadomatsu K.

Nephrol Dial Transplant     2014年

Neutrophil/lymphocyte ratio as a predictor of cardiovascular events in incident dialysis patients: a Japanese prospective cohort study. 査読有り

Abe T, Kato S, Tsuruta Y, Sugiura S, Katsuno T, Kosugi T, Tsuboi N, Matsuo S, Maruyama S.

Clin Exp Nephrol.     2014年

CD147/basigin reflects renal dysfunction in patients with acute kidney injury. 査読有り

Nagaya H, Kosugi T, Maeda-Hori M, Maeda K, Sato Y, Kojima H, Hayashi H, Kato N, Ishimoto T, Sato W, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S.

Clin Exp Nephrol.     2013年12月

High fat and high sucrose (western) diet induce steatohepatitis that is dependent on fructokinase. 査読有り

Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, Maclean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ.

Hepatology     2013年6月

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome. 査読有り

Lanaspa MA, Ishimoto T, Li N, Cicerchi C, Orlicky DJ, Ruzicky P, Rivard C, Inaba S, Roncal-Jimenez CA, Bales ES, Diggle CP, Asipu A, Petrash JM, Kosugi T, Maruyama S, Sanchez-Lozada LG, McManaman JL, Bonthron DT, Sautin YY, Johnson RJ.

Nat Commun.   ( 4 ) 頁： 2434   2013年

Uncoupling of VEGF with endothelial NO as a potential mechanism for abnormal angiogenesis in the diabetic nephropathy. 査読有り

Nakagawa T, Sato W, Kosugi T, Johnson RJ.

J Diabetes Res.     2013年

Toll-like receptor 3 ligand, polyIC, induces proteinuria and glomerular CD80, and increases urinary CD80 in mice. 査読有り

Ishimoto T, Shimada M, Gabriela G, Kosugi T, Sato W, Lee PY, Lanaspa MA, Rivard C, Maruyama S, Garin EH, Johnson RJ

Nephrol Dial Transplant.     2012年12月

Deficiency of Growth Factor Midkine Exacerbates Necrotizing Glomerular Injuries in Progressive Glomerulonephritis. 査読有り

Kojima H, Kosugi T, Sato W, Sato Y, Maeda K, Kato N, Kato K, Inaba S, Ishimoto T, Tsuboi N, Matsuo S, Maruyama S, Yuzawa Y, Kadomatsu K.

Am J Pathol.     2012年11月

Distribution of hydrogen sulfide (H(2)S)-producing enzymes and the roles of the H(2)S donor sodium hydrosulfide in diabetic nephropathy. 査読有り

Yamamoto J, Sato W, Kosugi T, Yamamoto T, Kimura T, Taniguchi S, Kojima H, Maruyama S, Imai E, Matsuo S, Yuzawa Y, Niki I.

Clin Exp Nephrol.     2012年8月

A rare case of acute kidney injury associated with autoimmune hemolytic anemia and thrombocytopenia after long-term usage of oxaliplatin. 査読有り

Ito I, Ito Y, Mizuno M, Suzuki Y, Yasuda K, Ozaki T, Kosugi T, Yasuda Y, Sato W, Tsuboi N, Maruyama S, Imai E, Matsuo S.

Clin Exp Nephrol.   16 巻 ( 3 ) 頁： 490-494   2012年6月

Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. 査読有り

Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sanchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ

Proc Natl Acad Sci U S A.   109 巻 ( 11 ) 頁： 4320-4325   2012年3月

Midkine and the kidney; health and diseases 招待有り 査読有り

Kosugi T and Sato W

Nephrol. Dial Transplant.     2011年12月

Selective Stimulation of VEGFR2 Accelerates Progressive Renal Disease. 査読有り

Sato W, Tanabe K, Kosugi T, Hudkins K, Lanaspa MA, Zhang L, Campbell-Thompson M, Li Q, Long DA, Alpers CE, Nakagawa T.

American Journal of Pathology     2011年5月

Growth factor Midkine is involved in the pathogenesis of renal injury induced by protein overload containing endotoxin. 査読有り

Kato K, Kosugi T, Sato W, Arata-Kawai H, Ozaki T, Tsuboi N, Ito I, Tawada H, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S.

Clin Exp Nephrol.     2011年3月

Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. 査読有り

Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K.

American Journal of Pathology.   178 巻 ( 2 ) 頁： 572-9   2011年2月

Endothelial dysfunction as a potential contributor in diabetic nephropathy. 査読有り

Nakagawa T, Tanabe K, Croker BP, Johnson RJ, Grant MB, Kosugi T, Li Q.

Nature Review Nephrology.   7 巻 ( 1 ) 頁： 36-44   2011年1月

Endothelial von Willebrand factor release due to eNOS deficiency predisposes to thrombotic microangiopathy in mouse aging kidney. 査読有り

Nakayama T, Sato W, Yoshimura A, Zhang L, Kosugi T, Campbell-Thompson M, Kojima H, Croker BP, Nakagawa T.

American Journal of Pathology.   176 巻 ( 5 ) 頁： 2198-208   2010年5月

Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice. 査読有り

Kosugi T, Nakayama T, Li Q, Chiodo VA, Zhang L, Campbell-Thompson M, Grant M, Croker BP, Nakagawa T.

Am J Physiol Renal Physiol.   298 巻 ( 3 ) 頁： F609-616   2010年3月

Dietary fructose causes tubulointerstitial injury in the normal rat kidney. 査読有り

Nakayama T, Kosugi T, Gersch M, Connor T, Sanchez-Lozada LG, Lanaspa MA, Roncal C, Perez-Pozo SE, Johnson RJ, Nakagawa T.

Am J Physiol Renal Physiol.   298 巻 ( 3 ) 頁： F712-20   2010年3月

eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists. 査読有り

Kosugi T, Heinig M, Nakayama T, Matsuo S, Nakagawa T.

American Journal of Pathology   176 巻 ( 2 ) 頁： 619-629   2010年2月

Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice. 査読有り

Kosugi T, Nakayama T, Heinig M, Zhang L, Yuzawa Y, Sanchez-Lozada LG, Roncal C, Johnson RJ, Nakagawa T.

Am J Physiol Renal Physiol.   297 巻 ( 2 ) 頁： F481-488   2009年8月

The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion 査読有り

Kato N, Yuzawa Y, Kosugi T, Hobo A, Sato W, Miwa Y, Sakamoto K, Matsuo S, Kadomatsu K.

Journal of American Society of Nephrology   20 巻 ( 7 ) 頁： 1565-1576   2009年7月

Abnormal angiogenesis in diabetic nephropathy. 査読有り

Nakagawa T, Kosugi T, Haneda M, Rivard CJ, Long DA.

Diabetes.   58 巻 ( 7 ) 頁： 1471-8   2009年7月

The growth factor midkine regulates the renin-angiotensin system in mice. 査読有り

Hobo A, Yuzawa Y, Kosugi T, Kato N, Asai N, Sato W, Maruyama S, Ito Y, Kobori H, Ikematsu S, Nishiyama A, Matsuo S, Kadomatsu K.

Journal of Clinical Investigation   119 巻 ( 6 ) 頁： 1616-1625   2009年6月

Endothelial injury due to eNOS deficiency accelerates the progression of chronic renal disease in the mouse. 査読有り

Nakayama T, Sato W, Kosugi T, Zhang L, Campbell-Thompson M, Yoshimura A, Croker BP, Johnson RJ, Nakagawa T.

American Jouenal of Physiology Renal Physiology   296 巻 ( 2 ) 頁： F317-27   2009年2月

Lowering blood pressure blocks mesangiolysis and mesangial nodules, but not tubulointerstitial injury, in diabetic eNOS knockout mice. 査読有り

Kosugi T, Heinig M, Nakayama T, Connor T, Yuzawa Y, Li Q, Hauswirth WW, Grant MB, Croker BP, Campbell-Thompson M, Zhang L, Atkinson MA, Segal MS, Nakagawa T.

American Journal of Pathology   174 巻 ( 4 ) 頁： 1221-1229   2009年2月

Uric acid and hypertension: an age-related relationship? 査読有り

Kosugi T, Nakagawa T, Kamath D, Richard RJ

J Hum Hypertens.   23 巻 ( 2 ) 頁： 75-76   2009年2月

Fructose induces the inflammatory molecule ICAM-1 in endothelial cells 査読有り

Glushakova O, Kosugi T, Roncal C, Mu W, Heinig M, Cirillo P, Sánchez-Lozada LG, Johnson RJ, Nakagawa T.

Journal of American Society of Nephrology   19 巻 ( 9 ) 頁： 1712-1720   2008年9月

Overexpression of calmodulin in pancreatic beta cells induces diabetic nephropathy. 査読有り

Yuzawa Y, Niki I, Kosugi T, Maruyama S, Yoshida F, Takeda M, Tagawa Y, Kaneko Y, Kimura T, Kato N, Yamamoto J, Sato W, Nakagawa T, Matsuo S.

Journal of American Society of Nephrology   19 巻 ( 9 ) 頁： 1701-1711   2008年9月

The pivotal role of VEGF on glomerular macrophage infiltration in advanced diabetic nephropathy. 査読有り

Sato W, Kosugi T, Zhang L, Roncal CA, Heinig M, Campbell-Thompson M, Yuzawa Y, Atkinson MA, Grant MB, Croker BP, Nakagawa T.

Laboratory Investigation   88 巻 ( 9 ) 頁： 949-961   2008年9月

Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy. 査読有り

Kosugi T, Yuzawa Y, Sato W, Arata-Kawai H, Suzuki N, Kato N, Matsuo S, Kadomatsu K.

Labratory Investigation   87 巻 ( 9 ) 頁： 903-913   2007年9月

Growth factor midkine is involved in the pathogenesis of diabetic nephropathy. 査読有り

Kosugi T, Yuzawa Y, Sato W, Kawai H, Matsuo S, Takei Y, Muramatsu T, Kadomatsu K.

American Journal of Pathology   168 巻 ( 1 ) 頁： 9-19   2006年1月

Lack of the growth factor midkine enhances survival against cisplatin-induced renal damage. 査読有り

Kawai H, Sato W, Yuzawa Y, Kosugi T, Matsuo S, Takei Y, Kadomatsu K, Muramatsu T.

American Journal of Pathology.   165 巻 ( 5 ) 頁： 1603-12   2004年11月

Autopsy case of the cerebellar form of progressive multifocal leukoencephalopathy without immunodeficiency. 査読有り

Arai Y, Tsutsui Y, Nagashima K, Shinmura Y, Kosugi T, Wakai M, Nishikage H, Yamamoto J.

Neuropathology.   22 巻 ( 1 ) 頁： 48-56   2002年3月

高温環境によるCKD発症の病態解明と細胞老化制御を介した治療標的の探索

研究課題/研究課題番号：20K08607  2020年4月 - 2023年3月

科学研究費助成事業  基盤研究(C)

佐藤 由香, 石本 卓嗣, 前田 佳哉輔, 小杉 智規

慢性腎臓病患者における腸内細菌叢の変化とその改善による新規治療戦略の開発

研究課題/研究課題番号：19K08700  2019年4月 - 2022年3月

科学研究費助成事業  基盤研究(C)

加藤 佐和子, 石本 卓嗣, 丸山 彰一, 小杉 智規

難治性腎疾患におけるCaMK4を介した新規ポドサイト特異的治療法の開発

研究課題/研究課題番号：19K08723  2019年4月 - 2022年3月

科学研究費助成事業  基盤研究(C)

前田 佳哉輔, 丸山 彰一, 古橋 和拡, 勝野 敬之, 小杉 智規, 加藤 規利

AKIにおける、CCR7を介したC5a経路制御機構の解明

研究課題/研究課題番号：19K08701  2019年4月 - 2021年3月

科学研究費助成事業  基盤研究(C)

小島 博, 水野 正司, 鈴木 康弘, 勝野 敬之, 小杉 智規

CD147による細胞内輸送・代謝機構の解明と糖鎖修飾調整を介した新規治療法の開発

研究課題/研究課題番号：17K09695  2017年4月 - 2020年3月

科学研究費助成事業  基盤研究(C)

小杉 智規, 丸山 彰一, 門松 健治

血管内皮障害を呈する腎疾患におけるSulf2の機能解析と新たな治療戦略の探求

研究課題/研究課題番号：17K09694  2017年4月 - 2019年3月

科学研究費助成事業  基盤研究(C)

増田 智広, 丸山 彰一, 内村 健治, 小杉 智規

RCTを用いたイコサペンタ酸（EPA）による腎保護戦略の確立と作用機序の解明

研究課題/研究課題番号：16K09633  2016年4月 - 2019年3月

林 宏樹

MKおよび血管拡張因子EETsを介した腎・血圧調節機構の解明と新規降圧療法の開発

研究課題/研究課題番号：16K09609  2016年4月 - 2019年3月

加藤 佐和子

ExosomesとマイクロRNAを用いた、安全性の高いオーダーメイド治療の開発

研究課題/研究課題番号：16K09610  2016年4月 - 2019年3月

加藤 規利

慢性腎臓病・高血圧におけるフルクトース代謝の役割と分子機構の解明

研究課題/研究課題番号：15K09255  2015年4月 - 2018年3月

石本 卓嗣

CD147による腎エネルギー代謝機構の解明と臓器相関に対する治療法の探求

2014年4月 - 2017年3月

科学研究費補助金  基盤研究(C)