2022/05/18 更新

写真a

ナカヤマ ゴロウ
中山 吾郎
NAKAYAMA Goro
所属
大学院医学系研究科 総合医学専攻 病態外科学 准教授
大学院担当
大学院医学系研究科
学部担当
医学部 医学科
職名
准教授

学位 1

  1. 医学博士 ( 2007年11月   名古屋大学 ) 

研究キーワード 2

  1. 大腸癌に対する外科的治療

  2. 炎症性腸疾患に対する外科治療

研究分野 1

  1. その他 / その他  / 消化器外科学

所属学協会 4

  1. 日本内視鏡外科学会   技術認定医

  2. 制癌剤適応研究会   幹事

  3. 大腸癌研究会   施設代表者,世話人

  4. 日本ロボット外科学会   認定医

委員歴 1

  1. 名古屋大学医学部附属病院IRB   専門分野委員(外科系)  

    2015年4月 - 現在   

 

論文 117

  1. Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer

    Sakata Kazuki, Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF ONCOLOGY   60 巻 ( 6 )   2022年6月

     詳細を見る

    記述言語:日本語  

    DOI: 10.3892/ijo.2022.5353

    Web of Science

    PubMed

  2. Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells

    Umeda Shinichi, Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Kodera Yasuhiro

    GASTRIC CANCER   25 巻 ( 3 ) 頁: 558 - 572   2022年5月

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  3. Direct Observation of Retinal Microvessels in Cancer Patients After Systemic Administration of Bevacizumab and Oxaliplatin.

    Mitsuma A, Ito Y, Shimokata T, Tanaka C, Uehara K, Nakayama G, Terasaki H, Ando Y

    Cancer diagnosis & prognosis   2 巻 ( 3 ) 頁: 330 - 335   2022年5月

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    記述言語:英語  

    DOI: 10.21873/cdp.10113

    PubMed

  4. Drain Amylase Concentrations at 3 h After Gastrectomy Enhance Early Prediction of Postoperative Peripancreatic Inflammatory Fluid Collection

    Nakanishi Koki, Kanda Mitsuro, Tanaka Chie, Takeda Shigeomi, Tanaka Katsuhito, Shimizu Dai, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    WORLD JOURNAL OF SURGERY   46 巻 ( 3 ) 頁: 648 - 655   2022年3月

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  5. The significance of the time to arterial perfusion in intraoperative ICG angiography during colorectal surgery

    Aiba Toshisada, Uehara Kay, Ogura Atsushi, Tanaka Aya, Yonekawa Yoshihiko, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki, Nagino Masato

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   35 巻 ( 12 ) 頁: 7227 - 7235   2021年12月

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  6. Neoadjuvant docetaxel, oxaliplatin plus S-1 for treating clinical stage III squamous cell carcinoma of the esophagus: Study protocol of an open-label phase II trial

    Kanda Mitsuro, Shimizu Dai, Miyata Kazushi, Maeda Osamu, Tanaka Chie, Inokawa Yoshikuni, Hattori Norofumi, Hayashi Masamichi, Ando Masahiko, Kuwatsuka Yachiyo, Murotani Kenta, Nakayama Goro, Koike Masahiko, Ando Yuichi, Ebata Tomoki, Kodera Yasuhiro

    CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS   24 巻   頁: 100853   2021年12月

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  7. Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

    Sunagawa Yuki, Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Kurimoto Keisuke, Tanaka Nobutake, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CLINICAL EPIGENETICS   13 巻 ( 1 ) 頁: 172   2021年12月

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  8. Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

    Kanda Mitsuro, Shimizu Dai, Nakamura Shunsuke, Sawaki Koichi, Umeda Shinichi, Miwa Takashi, Tanaka Haruyoshi, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Iguchi Yohei, Katsuno Masahisa, Kodera Yasuhiro

    ONCOGENE   40 巻 ( 36 ) 頁: 5495 - 5504   2021年9月

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  9. A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes

    Yamanaka Masaya, Hayashi Masamichi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   41 巻 ( 8 ) 頁: 3933 - 3940   2021年8月

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  10. G-protein subunit gamma-4 expression has potential for detection, prediction and therapeutic targeting in liver metastasis of gastric cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Sawaki Koichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   125 巻 ( 2 ) 頁: 220 - 228   2021年7月

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  11. High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences

    Hayashi Masamichi, Yamada Suguru, Tanabe Hiroshi, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   73 巻 ( 6 ) 頁: 996 - 1003   2021年7月

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  12. The carcinoembryonic antigen ratio is a potential predictor of survival in recurrent colorectal cancer

    Suzuki Yumi, Ogura Atsushi, Uehara Kay, Aiba Toshisada, Ohara Noriaki, Murata Yuki, Jinno Takanori, Mishina Takuya, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Ebata Tomoki

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   26 巻 ( 7 ) 頁: 1264 - 1271   2021年7月

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  13. Novel prognostic implications of YTH domain family 2 in resected hepatocellular carcinoma

    Nakagawa Nobuhiko, Sonohara Fuminori, Tanaka Katsuhito, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ONCOLOGY LETTERS   22 巻 ( 1 ) 頁: 538   2021年7月

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    記述言語:日本語  

    DOI: 10.3892/ol.2021.12799

    Web of Science

    PubMed

  14. miR-23b-3p Plays an Oncogenic Role in Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Kurimoto Keisuke, Tanabe Hiroshi, Hirabayashi Sho, Sonohara Fuminori, Inokawa Yoshikuni, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   28 巻 ( 6 ) 頁: 3416 - 3426   2021年6月

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  15. Indications for neoadjuvant treatment based on risk factors for poor prognosis before and after neoadjuvant chemotherapy alone in patients with locally advanced rectal cancer

    Ogura Atsushi, Uehara Kay, Aiba Toshisada, Sando Masanori, Tanaka Aya, Ohara Noriaki, Murata Yuki, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Ebata Tomoki, Kodera Yasuhiro, Nagino Masato

    EJSO   47 巻 ( 5 ) 頁: 1005 - 1011   2021年5月

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  16. Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway

    Miwa Takashi, Kanda Mitsuro, Shimizu Dai, Umeda Shinichi, Sawaki Koichi, Tanaka Haruyoshi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    BRITISH JOURNAL OF CANCER   124 巻 ( 8 ) 頁: 1449 - 1460   2021年4月

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  17. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma

    Suenaga Masaya, Fujii Tsutomu, Yamada Suguru, Hayashi Masamichi, Shinjo Keiko, Takami Hideki, Niwa Yukiko, Sonohara Fuminori, Shimizu Dai, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kondo Yutaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   28 巻 ( 4 ) 頁: 2277 - 2286   2021年4月

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  18. Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

    Sunagawa Yuki, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Tanaka Nobutake, Suzuki Yunosuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    SCIENTIFIC REPORTS   11 巻 ( 1 ) 頁: 6016   2021年3月

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  19. Tissue RNFT2 Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer

    Sasahara Masahiro, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Nakayama Goro, Kodera Yasuhiro

    ANTICANCER RESEARCH   41 巻 ( 2 ) 頁: 609 - 617   2021年2月

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  20. Randomised phase II trial of capecitabine plus oxaliplatin with continuous versus intermittent use of oxaliplatin as adjuvant chemotherapy for stage II/III colon cancer (CCOG-1302 study)

    Nakayama Goro, Takano Nao, Taniguchi Hiroya, Ishigure Kiyoshi, Yokoyama Hiroyuki, Teramoto Hitoshi, Hashimoto Ryoji, Sakai Mitsuru, Ishiyama Akiharu, Kinoshita Takashi, Hayashi Naomi, Nakamura Masanori, Hattori Norifumi, Sato Yusuke, Umeda Shinichi, Uehara Kei, Aiba Toshisada, Sonohara Fuminori, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Murotani Kenta, Ando Masahiko, Ando Yuichi, Muro Kei, Kodera Yasuhiro

    EUROPEAN JOURNAL OF CANCER   144 巻   頁: 61 - 71   2021年2月

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  21. Development of novel combination cancer immunotherapy using anti-PD-1 and anti-PD-L1 antibody

    Hasegawa Hirotaka, Sugiyama Daisuke, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Nomoto Shuji, Fujiwara Michitaka, Kodera Yasuhiro, Nishikawa Hiroyoshi

    CANCER SCIENCE   112 巻   頁: 741 - 741   2021年2月

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    記述言語:日本語  

    Web of Science

  22. Function and prognostic value of melanoma-associated antigen-D4 protein in esophageal squamous cell carcinoma

    Sawaki Koichi, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Uno Yasuo, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   112 巻   頁: 531 - 531   2021年2月

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    記述言語:日本語  

    Web of Science

  23. Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301)

    Miwa Keisuke, Oki Eiji, Enomoto Masanobu, Ihara Keisuke, Ando Koji, Fujita Fumihiko, Tominaga Masahiro, Mori Shinichiro, Nakayama Goro, Shimokawa Mototsugu, Saeki Hiroshi, Baba Hideo, Mori Masaki, Akagi Yoshito

    BMC CANCER   21 巻 ( 1 ) 頁: 23   2021年1月

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  24. Perioperative assessment of indocyanine green elimination rate accurately predicts postoperative liver failure in patients undergoing hepatectomy

    Sunagawa Yuki, Yamada Suguru, Kato Yoshiyasu, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   28 巻 ( 1 ) 頁: 86 - 94   2021年1月

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    記述言語:日本語  

    DOI: 10.1002/jhbp.833

    Web of Science

    PubMed

  25. Age-Related Differences in the Prognosis of Pancreatic Cancer According to Perioperative Systemic Therapy

    Sonohara Fuminori, Yamada Suguru, Kurimoto Keisuke, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   50 巻 ( 1 ) 頁: 37 - 46   2021年1月

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  26. Pancreatic Fat and Body Composition Measurements by Computed Tomography are Associated with Pancreatic Fistula After Pancreatectomy

    Tanaka Katsuhito, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   28 巻 ( 1 ) 頁: 530 - 538   2021年1月

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  27. Different Characteristics of Serum Alfa Fetoprotein and Serum Des-gamma-carboxy Prothrombin in Resected Hepatocellular Carcinoma

    Hayashi Masamichi, Yamada Suguru, Takano Nao, Okamura Yukiyasu, Takami Hideki, Inokawa Yoshikuni, Sonohara Fuminori, Tanaka Nobutake, Shimizu Dai, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   35 巻 ( 3 ) 頁: 1749 - 1760   2021年

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    記述言語:日本語  

    DOI: 10.21873/invivo.12434

    Web of Science

    PubMed

  28. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue

    Nakagawa Nobuhiko, Tanaka Katsuhito, Sonohara Fuminori, Kandimalla Raju, Sunagawa Yuki, Inokawa Yoshikuni, Takami Hideki, Hayashi Masamichi, Yamada Suguru, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   40 巻 ( 12 ) 頁: 6665 - 6676   2020年12月

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  29. AMIGO2 Expression as a Potential Prognostic Biomarker for Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   40 巻 ( 12 ) 頁: 6713 - 6721   2020年12月

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  30. What is the impact of systemic chemotherapy for lateral lymph nodes in patients with locally advanced low rectal cancer?

    Ogura Atsushi, Uehara Kay, Aiba Toshisada, Hattori Norifumi, Nakayama Goro, Maeda Osamu, Ando Yuichi, Kodera Yasuhiro, Ebata Tomoki, Nagino Masato

    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE   35 巻 ( 11 ) 頁: 2073 - 2080   2020年11月

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  31. AnOpen-Label Single-ArmPhaseIIStudy of Treatment with Neoadjuvant S-1 Plus Cisplatin for Clinical StageIIISquamous Cell Carcinoma of the Esophagus

    Kanda Mitsuro, Koike Masahiko, Iwata Naoki, Shimizu Dai, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Omae Kenji, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGIST   25 巻 ( 11 ) 頁: E1650 - E1654   2020年11月

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  32. Characteristics Associated with Nodal and Distant Recurrence after Curative Resection of Squamous Cell Carcinoma of the Thoracic Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Hayashi Masamichi, Hattori Norifumi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   231 巻 ( 4 ) 頁: E121 - E121   2020年10月

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    記述言語:日本語  

    Web of Science

  33. An outcome analysis of predictive factors for portal or splenic vein thrombosis after distal pancreatectomy

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SURGERY TODAY   50 巻 ( 10 ) 頁: 1282 - 1289   2020年10月

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  34. The impact of cancer stem cell markers in the tissues of pancreatic ductal adenocarcinoma for prognosis after surgical resections

    Inokawa Yoshikuni, Yamada Suguru, Hayashi Masamichi, Sunagawa Yuki, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    CANCER RESEARCH   80 巻 ( 16 )   2020年8月

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    記述言語:日本語  

    DOI: 10.1158/1538-7445.AM2020-6016

    Web of Science

  35. Importance of the neoadjuvant rectal (NAR) score to the outcome of neoadjuvant chemotherapy alone for locally advanced rectal cancer

    Mukai Toshiki, Uehara Keisuke, Aiba Toshisada, Ogura Atsushi, Tsuzuki Toyonori, Tanaka Aya, Sando Masanori, Ohara Noriyuki, Sato Yusuke, Hattori Norifumi, Nakayama Goro, Kodera Yasuhiro, Nagino Masato

    SURGERY TODAY   50 巻 ( 8 ) 頁: 912 - 919   2020年8月

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  36. Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan

    Taniguchi Hiroya, Uehara Keisuke, Nakayama Goro, Nakayama Hiroshi, Aiba Toshisada, Hattori Norifumi, Kataoka Masato, Nakano Yasuyuki, Kawase Yoshihisa, Okochi Osamu, Matsuoka Hiroshi, Utsunomiya Setsuo, Sakamoto Eiji, Mori Yoshinori, Umeda Shinichi, Shikano Toshio, Komori Koji, Tajika Masahiro, Kadowaki Shigenori, Muro Kei, Yatabe Yasushi

    TRANSLATIONAL ONCOLOGY   13 巻 ( 7 ) 頁: 100786   2020年7月

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  37. Novel Prognostic Implications of DUPAN-2 in the Era of Initial Systemic Therapy for Pancreatic Cancer

    Sunagawa Yuki, Yamada Suguru, Sato Yusuke, Morimoto Daishi, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   27 巻 ( 6 ) 頁: 2081 - 2089   2020年6月

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  38. Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CANCER   146 巻 ( 10 ) 頁: 2865 - 2876   2020年5月

     詳細を見る

    記述言語:日本語  

    DOI: 10.1002/ijc.32705

    Web of Science

    PubMed

  39. Clinical impact of additional therapy for residual pancreatic cancer

    Yamada Suguru, Sonohara Fuminori, Tashiro Mitsuru, Murotani Kenta, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    SURGERY TODAY   50 巻 ( 5 ) 頁: 440 - 448   2020年5月

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  40. Optimized Cutoff Value of Serum Squamous Cell Carcinoma Antigen Concentration Accurately Predicts Recurrence After Curative Resection of Squamous Cell Carcinoma of the Esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hattori Norifumi, Hayashi Masamichi, Omae Kenji, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   27 巻 ( 4 ) 頁: 1233 - 1240   2020年4月

     詳細を見る

  41. Exploration of Exosomal Micro RNA Biomarkers Related to Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

    Sonohara Fuminori, Yamada Suguru, Takeda Shigeomi, Hayashi Masamichi, Suenaga Masaya, Sunagawa Yuki, Tashiro Mitsuru, Takami Hideki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANTICANCER RESEARCH   40 巻 ( 4 ) 頁: 1843 - 1853   2020年4月

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  42. Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer

    Nakagawa Nobuhiko, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   27 巻 ( 3 ) 頁: 887 - 895   2020年3月

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  43. Randomized phase II trial of CAPOX with continuous versus intermittent use of oxaliplatin as an adjuvant chemotherapy after curative resection of stage II/III colon cancer (CCOG-1302 study)

    Nakamura Masanori, Nakayama Goro, Ishigure Kiyoshi, Mashita Naoki, Yokoyama Hiroyuki, Hattori Norifumi, Uehara Keisuke, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   38 巻 ( 4 )   2020年2月

     詳細を見る

    記述言語:日本語  

    Web of Science

  44. Predictive value of the modified systemic inflammation score in patients undergoing curative resection of squamous cell carcinoma of the esophagus

    Kanda Mitsuro, Koike Masahiko, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Sonohara Fuminori, Takami Hideki, Inokawa Yoshikuni, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   38 巻 ( 4 )   2020年2月

     詳細を見る

    記述言語:日本語  

    Web of Science

  45. A prospective trial to evaluate treatment effects of a beta-hydroxy-beta-methylbutyrate containing nutrient for leakage a the anastomotic site after esophagectomy

    Kanda Mitsuro, Koike Masahiko, Fukaya Masahide, Miyata Kazushi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Murotani Kenta, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    NAGOYA JOURNAL OF MEDICAL SCIENCE   82 巻 ( 1 ) 頁: 33 - 37   2020年2月

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    記述言語:日本語  

    DOI: 10.18999/nagjms.82.1.33

    Web of Science

    PubMed

  46. The Significance of Molecular Biomarkers on Clinical Survival Outcome Differs Depending on Colon Cancer Sidedness

    Hirabayashi Sho, Hayashi Masamichi, Nakayama Goro, Mii Shinji, Hattori Norifumi, Tanabe Hiroshi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Takahashi Masahide, Kodera Yasuhiro

    ANTICANCER RESEARCH   40 巻 ( 1 ) 頁: 201 - 211   2020年1月

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  47. Phase II study of capecitabine plus oxaliplatin (CapOX) as adjuvant chemotherapy for locally advanced rectal cancer (CORONA II)

    Hattori Norifumi, Nakayama Goro, Uehara Keisuke, Aiba Toshisada, Ishigure Kiyoshi, Sakamoto Eiji, Tojima Yuichiro, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Nagino Masato, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   25 巻 ( 1 ) 頁: 118 - 125   2020年1月

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  48. STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer

    Nakamura Shunsuke, Kanda Mitsuro, Shimizu Dai, Sawaki Kouichi, Tanaka Chie, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    CANCER GENOMICS & PROTEOMICS   17 巻 ( 5 ) 頁: 509 - 516   2020年

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    記述言語:日本語  

    DOI: 10.21873/cgp.20207

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  49. Correlation Between the Metabolic Conversion of a Capecitabine Metabolite, 5 '-Deoxy-5-fluorocytidine, and Creatinine Clearance

    Inaishi Takahiro, Fujita Ken-Ichi, Matsumoto Natsumi, Shimokata Tomoya, Maeda Osamu, Kikumori Toyone, Hattori Norifumi, Nakayama Goro, Ando Yuichi

    IN VIVO   34 巻 ( 6 ) 頁: 3539 - 3544   2020年

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    記述言語:日本語  

    DOI: 10.21873/invivo.12196

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  50. Characteristics of Lung Metastasis as an Initial Recurrence Pattern After Curative Resection of Pancreatic Cancer

    Morimoto Daishi, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   49 巻 ( 5 ) 頁: 699 - 705   2020年

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  51. Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Umeda Shinichi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   39 巻 ( 11 ) 頁: 6125 - 6133   2019年11月

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  52. Comparison of non-invasive liver reserve and fibrosis models: Implications for surgery and prognosis for hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Tashiro Mitsuru, Sunagawa Yuki, Morimoto Daishi, Tanaka Haruyoshi, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HEPATOLOGY RESEARCH   49 巻 ( 11 ) 頁: 1305 - 1315   2019年11月

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    記述言語:日本語  

    DOI: 10.1111/hepr.13400

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  53. Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma

    Uno Yasuo, Kanda Mitsuro, Sato Yusuke, Shimizu Dai, Umeda Shinichi, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Motoyama Satoru, Koike Masahiko, Kodera Yasuhiro

    ANTICANCER RESEARCH   39 巻 ( 11 ) 頁: 6015 - 6023   2019年11月

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  54. Feasibility of subtotal esophagectomy with systematic lymphadenectomy in selected elderly patients with esophageal cancer; a propensity score matching analysis

    Kanda Mitsuro, Koike Masahiko, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Omae Kenji, Kodera Yasuhiro

    BMC SURGERY   19 巻 ( 1 ) 頁: 143   2019年10月

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  55. Randomized phase II trial of CAPOX with planned oxaliplatin stop-and-go strategy as adjuvant chemotherapy after curative resection of colon cancer (CCOG-1302 study)

    Yokoyama H., Nakayama G., Ishigure K., Hayashi N., Tanaka K., Tsutsuyama M., Hattori N., Yamada S., Kodera Y.

    ANNALS OF ONCOLOGY   30 巻   2019年10月

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    記述言語:日本語  

    Web of Science

  56. Novel implications of combined arterial resection for locally advanced pancreatic cancer in the era of newer chemo-regimens

    Sonohara Fuminori, Yamada Suguru, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    EJSO   45 巻 ( 10 ) 頁: 1895 - 1900   2019年10月

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  57. Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer

    Kato Yoshiyasu, Yamada Suguru, Tashiro Mitsuru, Sonohara Fuminori, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    HPB   21 巻 ( 9 ) 頁: 1211 - 1218   2019年9月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.hpb.2019.01.012

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  58. Functions of FRAS1 as a driver gene of liver metastasis from gastric cancer analyzed by the genome editing technology

    Umeda Shinichi, Kanda Mitsuro, Tanaka Haruyoshi, Sonohara Fuminori, Takami Hideki, Hattori Norifumi, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER RESEARCH   79 巻 ( 13 )   2019年7月

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    記述言語:日本語  

    DOI: 10.1158/1538-7445.AM2019-863

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  59. Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy

    Miwa Takashi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF GASTRIC CANCER   19 巻 ( 2 ) 頁: 183 - 192   2019年6月

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    記述言語:日本語  

    DOI: 10.5230/jgc.2019.19.e15

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  60. Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival

    Miwa Takashi, Kanda Mitsuro, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   26 巻 ( 5 ) 頁: 1535 - 1543   2019年5月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1245/s10434-019-07166-5

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  61. Neoadjuvant CAPOX and bevacizumab alone for locally advanced rectal cancer: long-term results from the N-SOG 03 trial

    Tomida Akihiro, Uehara Keisuke, Hiramatsu Kazuhiro, Maeda Atsuyuki, Sakamoto Eiji, Okada Yoshito, Kurumiya Yasuhiro, Nakayama Goro, Nakamura Masanao, Aiba Toshisada, Nagino Masato

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   24 巻 ( 4 ) 頁: 403 - 410   2019年4月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10147-018-1372-6

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  62. Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer

    Uno Yasuo, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   26 巻 ( 3 ) 頁: 836-844   2019年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1245/s10434-018-07149-y

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  63. Prediction of peritoneal recurrences of gastric cancer by qPCR analysis of peritoneal lavage fluids.

    Nakanishi Koki, Kanda Mitsuro, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   37 巻 ( 4 )   2019年2月

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    記述言語:日本語  

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  64. Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

    Niwa Yukiko, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Hayashi Masamichi, Tashiro Mitsuru, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF TRANSLATIONAL MEDICINE   17 巻 ( 1 ) 頁: 1   2019年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s12967-018-1762-6

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  65. Perioperative and prognostic implication of albumin-bilirubin-TNM score in Child-Pugh class A hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Sugimoto Hiroyuki, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF GASTROENTEROLOGICAL SURGERY   3 巻 ( 1 ) 頁: 65-74   2019年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/ags3.12212

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  66. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma

    Suenaga M., Fujii T., Yamada S., Hayashi M., Shinjo K., Takami H., Niwa Y., Sonohara F., Shimizu D., Kanda M., Kobayashi D., Tanaka C., Nakayama G., Koike M., Fujiwara M., Kondo Y., Kodera Y.

    PANCREAS   48 巻 ( 10 ) 頁: 1528 - 1528   2019年

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    記述言語:日本語  

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  67. Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines

    Miwa Takashi, Kanda Mitsuro, Umeda Shinichi, Tanaka Haruyoshi, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Kodera Yasuhiro

    IN VIVO   33 巻 ( 6 ) 頁: 1785 - 1792   2019年

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    記述言語:日本語  

    DOI: 10.21873/invivo.11669

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  68. A New Biomarker for Peritoneal Lavage Using Digital PCR in Patients with Pancreatic Ductal Adenocarcinoma

    Suenaga Masaya, Yamada Suguru, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 650-650   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  69. Pattern-specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 1128-1128   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  70. Integrated multigene expression panel to prognosticate patients with gastric cancer

    Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Hayashi Masamichi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 769-769   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  71. FRAS1 expression reflects the malignancy potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 1128-1128   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  72. Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma

    Umeda Shinichi, Kanda Mitsuro, Koike Masahiko, Tanaka Haruyoshi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGY REPORTS   40 巻 ( 6 ) 頁: 3772-3780   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3892/or.2018.6742

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  73. Troponin I2 as a specific biomarker for prediction of peritoneal metastasis in gastric cancer

    Sawaki Koichi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 765-765   2018年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  74. Transanal extended rectal surgery with lateral pelvic lymph node dissection

    Aiba T., Uehara K., Mukai T., Hattori N., Nakayama G., Nagino M.

    TECHNIQUES IN COLOPROCTOLOGY   22 巻 ( 11 ) 頁: 893-894   2018年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10151-018-1891-1

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  75. Treatment strategy of intraperitoneal and systemic chemotherapy combined with gastrectomy for gastric cancer with peritoneal metastasis

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   33 巻   頁: 98-98   2018年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  76. Expression of sushi domain containing two reflects the malignant potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   7 巻 ( 10 ) 頁: 5194-5204   2018年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/cam4.1793

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  77. Clinical Impact of Neoadjuvant Therapy on Nutritional Status in Pancreatic Cancer

    Tashiro Mitsuru, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   25 巻 ( 11 ) 頁: 3365-3371   2018年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1245/s10434-018-6699-8

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  78. A longitudinal study of a new point-of-care nerve conduction device for quantitative assessment of chemotherapy-induced peripheral neurotoxicity

    Matsuoka A., Maeda O., Mitsuma A., Uehara K., Nakayama G., Nagino M., Kodera Y., Ando Y.

    ANNALS OF ONCOLOGY   29 巻   2018年10月

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    記述言語:日本語  

    Web of Science

  79. Comparison of the Survival Outcomes of Pancreatic Cancer and Intraductal Papillary Mucinous Neoplasms

    Yamada Suguru, Fujii Tsutomu, Hirakawa Akihiro, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   47 巻 ( 8 ) 頁: 974 - 979   2018年9月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MPA.0000000000001110

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  80. Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Umeda Shinichi, Shibata Masahiro, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    MOLECULAR CANCER RESEARCH   16 巻 ( 9 ) 頁: 1420-1429   2018年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1158/1541-7786.MCR-17-0467

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  81. Impact of the Controlling Nutritional Status Score on the Prognosis After Curative Resection of Pancreatic Ductal Adenocarcinoma

    Kato Yoshiyasu, Yamada Suguru, Suenaga Masaya, Takami Hideki, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   47 巻 ( 7 ) 頁: 823-829   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MPA.0000000000001105

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  82. Randomized Phase II Trial of CapOX plus Bevacizumab and CapIRI plus Bevacizumab as First-Line Treatment for Japanese Patients with Metastatic Colorectal Cancer (CCOG-1201 Study)

    Nakayama Goro, Mitsuma Ayako, Sunagawa Yuki, Ishigure Kiyoshi, Yokoyama Hiroyuki, Matsui Takanori, Nakayama Hiroshi, Nakata Kazuhiko, Ishiyama Akiharu, Asada Takahiro, Umeda Shinichi, Ezaka Kazuhiro, Hattori Norifumi, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    ONCOLOGIST   23 巻 ( 8 ) 頁: 919 - 927   2018年8月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1634/theoncologist.2017-0640

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  83. Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   25 巻 ( 7 ) 頁: 2083-2090   2018年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1245/s10434-018-6480-z

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  84. Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Suenaga Masaya, Hayashi Masamichi, Takami Hideki, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SCIENTIFIC REPORTS   8 巻 ( 1 ) 頁: 9846   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/s41598-018-28253-9

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  85. A Multicenter Clinical Phase II Study of FOLFOXIRI Plus Bevacizumab as First-line Therapy in Patients With Metastatic Colorectal Cancer: QUATTRO Study

    Oki Eiji, Kato Takeshi, Bando Hideaki, Yoshino Takayuki, Muro Kei, Taniguchi Hiroya, Kagawa Yoshinori, Yamazaki Kentaro, Yamaguchi Tatsuro, Tsuji Akihito, Iwamoto Shigeyoshi, Nakayama Goro, Emi Yasunori, Touyama Tetsuo, Nakamura Masato, Kotaka Masahito, Sakisaka Hideki, Yamanaka Takeharu, Kanazawa Akiyoshi

    CLINICAL COLORECTAL CANCER   17 巻 ( 2 ) 頁: 147 - 155   2018年6月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.clcc.2018.01.011

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  86. Significance of Lysyl oxidase-like 2 gene expression on the epithelial-mesenchymal status of hepatocellular carcinoma

    Ninomiya Go, Yamada Suguru, Hayashi Masamichi, Takeda Shigeomi, Suenaga Masaya, Takami Hideki, Kanda Mitsuro, Iwata Naoki, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOLOGY REPORTS   39 巻 ( 6 ) 頁: 2664-2672   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3892/or.2018.6349

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  87. Postoperative adalimumab maintenance therapy for Japanese patients with Crohn's disease: a single-center, single-arm phase II trial (CCOG-1107 study)

    Asada Takahiro, Nakayama Goro, Tanaka Chie, Kobayashi Daisuke, Ezaka Kazuhiro, Hattori Norifumi, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    SURGERY TODAY   48 巻 ( 6 ) 頁: 609-617   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s00595-018-1634-y

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  88. IDENTIFICATION OF MOLECULES DRIVING HEPATIC METASTASIS FORMATION OF GASTRIC CANCER CELLS

    Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    GUT   67 巻   頁: A5-A5   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1136/gutjnl-2018-IDDFabstracts.12

    Web of Science

  89. A novel dual-marker expression panel for easy and accurate risk stratification of patients with gastric cancer

    Kanda Mitsuro, Murotani Kenta, Tanaka Haruyoshi, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Hattori Norifumi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   7 巻 ( 6 ) 頁: 2463-2471   2018年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/cam4.1522

    Web of Science

    PubMed

  90. Integrated multigene expression panel to prognosticate patients with gastric cancer.

    Kanda M, Murotani K, Tanaka H, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Hattori N, Suenaga M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Oncotarget   9 巻 ( 27 ) 頁: 18775-18785   2018年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.18632/oncotarget.24661

    PubMed

  91. Clinical implication of nutrition for neoadjuvant therapy and impact of nutritional support in pancreatic cancer.

    Tashiro Mitsuru, Yamada Suguru, Fujii Tsutomu, Hattori Norifumi, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   36 巻 ( 4 ) 頁: .   2018年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  92. Randomized phase II trial of CapOX plus bevacizumab versus CapIRI plus bevacizumab as first-line treatment in Japanese patients with metastatic colorectal cancer (CCOG-1201).

    Sasahara Masahiro, Nakayama Goro, Ishigure Kiyoshi, Yokoyama Hiroyuki, Uehara Keisuke, Ishiyama Akiharu, Matsui Takanori, Nakayama Hiroshi, Kobayashi Daisuke, Umeda Shinichi, Sunagawa Yuki, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   36 巻 ( 4 ) 頁: .   2018年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  93. Phase II trial of oral S-1 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard chemotherapies (CCOG-1105 study).

    Ezaka Kazuhiro, Nakayama Goro, Yokoyama Hiroyuki, Matsui Takanori, Umeda Shinichi, Sunagawa Yuki, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   36 巻 ( 4 ) 頁: .   2018年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  94. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer.

    Yamada Suguru, Fujii Tsutomu, Takano Nao, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   36 巻 ( 4 ) 頁: .   2018年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  95. Identification of a novel molecule target for the diagnosis, prediction, and treatment of hepatic metastasis of gastric cancer.

    Kanda Mitsuro, Tanaka Haruyoshi, Miwa Takashi, Kobayashi Daisuke, Tanaka Chie, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   36 巻 ( 4 ) 頁: .   2018年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  96. Effectiveness of plasma activated lactated Ringer's solution on pancreatic cancer cells in vitro and in vivo

    Sato Yusuke, Yamada Suguru, Takeda Shigeomi, Kanda Mitsuo, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   109 巻   頁: 707-707   2018年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  97. Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification

    Morimoto Daishi, Yamada Suguru, Murotani Kenta, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tashiro Mitsuru, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   47 巻 ( 10 ) 頁: 1350-1356   2018年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MPA.0000000000001186

    Web of Science

    PubMed

  98. Efficacy and safety of CapeIRI plus bevacizumab therapy as a second-line treatment for patients with metastatic colorectal cancer

    Sunagawa Y., Nakayama G., Hattori N., Ezaka K., Uda H., Umeda S., Sato B., Yamada S., Sugimito H., Koike M., Kodera Y.

    ANNALS OF ONCOLOGY   28 巻   頁: .   2017年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  99. Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society

    Yamada Suguru, Fujii Tsutomu, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Sugimoto Hiroyuki, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    SURGERY   162 巻 ( 4 ) 頁: 784-791   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.surg.2017.04.023

    Web of Science

    PubMed

  100. FAM46C Serves as a Predictor of Hepatic Recurrence in Patients with Resectable Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Niwa Yukiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   24 巻 ( 11 ) 頁: 3438-3445   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1245/s10434-016-5636-y

    Web of Science

    PubMed

  101. Involvement of the immunoregulator MZB1 in progression of gastric cancer

    Tanaka Y., Kanda M., Tanaka C., Kobayashi D., Tanaka H., Takami H., Hayashi M., Iwata N., Niwa Y., Yamada S., Nakayama G., Sugimoto H., Koike M., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   28 巻   頁: .   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  102. Primary efficacy results and clinical impact of UGT1A1 genotype on safety from a Phase II study of FOLFOXIRI plus bevacizumab in patients with metastatic colorectal cancer: The QUATTRO study

    Bando H., Kato T., Yoshino T., Muro K., Yamazaki K., Yamaguchi T., Oki E., Iwamoto S., Tsuji A., Nakayama G., Emi Y., Touyama T., Nakamura M., Kotaka M., Kagawa Y., Taniguchi H., Sakisaka H., Yamanaka T., Kanazawa A.

    ANNALS OF ONCOLOGY   28 巻   頁: .   2017年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  103. Usefulness of preoperative estimated glomerular filtration rate to predict complications after curative gastrectomy in patients with clinical T2-4 gastric cancer

    Tanaka Yuri, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Mizuno Akira, Iwata Naoki, Hayashi Masamichi, Niwa Yukiko, Takami Hideki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Kodera Yasuhiro

    GASTRIC CANCER   20 巻 ( 4 ) 頁: 736-743   2017年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10120-016-0657-6

    Web of Science

    PubMed

  104. Stapling an extracorporeal Billroth-I anastomosis by the complete double stapling technique after laparoscopy-assisted distal gastrectomy

    Tanaka Chie, Fujiwara Michitaka, Kanda Mitsuro, Murotani Kenta, Iwata Naoki, Hayashi Masamichi, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY   10 巻 ( 2 ) 頁: 137-142   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1111/ases.12357

    Web of Science

    PubMed

  105. The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902)

    Nakayama Goro, Ishigure Kiyoshi, Yokoyama Hiroyuki, Uehara Keisuke, Kojima Hiroshi, Ishiyama Akiharu, Hayashi Naomi, Takano Nao, Hattori Norifumi, Kobayashi Daisuke, Tanaka Chie, Hayashi Masamichi, Kanda Mitsuro, Yamada Suguru, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    BMC CANCER   17 巻 ( 1 ) 頁: 243   2017年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s12885-017-3245-1

    Web of Science

    PubMed

  106. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma: A retrospective cohort study

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Yabusaki Norimitsu, Suzuki Kojiro, Iwata Naoki, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF SURGERY   39 巻   頁: 45-51   2017年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijsu.2017.01.075

    Web of Science

    PubMed

  107. The Charlson age comorbidity index predicts prognosis in patients with resected pancreatic cancer

    Asano Tomonari, Yamada Suguru, Fujii Tsutomu, Yabusaki Norimitsu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF SURGERY   39 巻   頁: 169-175   2017年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijsu.2017.01.115

    Web of Science

    PubMed

  108. GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer

    Shimizu Dai, Kanda Mitsuro, Tanaka Haruyoshi, Kobayashi Daisuke, Tanaka Chie, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Takami Hideki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    SCIENTIFIC REPORTS   7 巻   頁: 42089   2017年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/srep42089

    Web of Science

    PubMed

  109. The Charlson age comorbidity index to predict prognosis in patients with resected pancreatic cancer.

    Asano Tomonari, Fujii Tsutomu, Yamada Suguru, Yabusaki Norimitsu, Ninomiya Go, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 ) 頁: .   2017年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  110. Tumor infiltrative pattern predicts sites of recurrence after curative gastrectomy for gastric cancer.

    Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    DOI: 10.1200/JCO.2017.35.4_suppl.38

    Web of Science

  111. The efficacy and safety of CapeOX plus bevacizumab therapy with a planned oxaliplatin stop-and-go strategy in patients with metastatic colorectal cancer: A multicenter, single-arm, phase II study (CCOG-0902 study).

    Sunakawa Yuuki, Nakayama Goro, Ishigure Kiyoshi, Yokoyama Hiroyuki, Uehara Keisuke, Kanda Mitsuro, Murotani Kenta, Fujii Tsutomu, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    Web of Science

  112. Inverse probability of treatment weighting analysis of upfront surgery versus neoadjuvant chemoradiotherapy followed by surgery for pancreatic adenocarcinoma with arterial abutment.

    Fujii Tsutomu, Yamada Suguru, Murotani Kenta, Takami Hideki, Hayashi Masamichi, Kanda Mitsuro, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    Web of Science

  113. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma.

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Asano Tomonari, Takano Nao, Takami Hideki, Iwata Naoki, Kanda Mitsuro, Niwa Yukiko, Hayashi Masamichi, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Koike Masahiko, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    Web of Science

  114. Clinical implication of inflammation-based prognostic score and perioperative nutrition control in pancreatic cancer.

    Takano Nao, Yamada Suguru, Fujii Tsutomu, Tashiro Mitsuru, Tanaka Nobutake, Morimoto Daishi, Ninomiya Go, Niwa Yukiko, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    Web of Science

  115. Conversion surgery for unresectable gastric cancer following complete response of distant metastasis by systemic chemotherapy.

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Iwata Naoki, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   35 巻 ( 4 )   2017年2月

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    記述言語:日本語  

    Web of Science

  116. The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

    Shimizu Dai, Kanda Mitsuro, Sugimoto Hiroyuki, Shibata Masahiro, Tanaka Haruyoshi, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF ONCOLOGY   50 巻 ( 2 ) 頁: 381-386   2017年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3892/ijo.2017.3833

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    PubMed

  117. PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma

    Kurimoto Keisuke, Hayashi Masamichi, Guerrero-Preston Rafael, Koike Masahiko, Kanda Mitsuro, Hirabayashi Sho, Tanabe Hiroshi, Takano Nao, Iwata Naoki, Niwa Yukiko, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    EPIGENETICS   12 巻 ( 10 ) 頁: 865-874   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1080/15592294.2017.1365207

    Web of Science

    PubMed

▼全件表示

科研費 2

  1. クローン病術後抗TNFα抗体維持療法の有効性と安全性に関する検討

    研究課題/研究課題番号:22K08768  2022年4月 - 2026年3月

    科学研究費助成事業  基盤研究(C)

    中山 吾郎

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    担当区分:研究代表者 

    配分額:4290000円 ( 直接経費:3300000円 、 間接経費:990000円 )

  2. クローン病術後抗TNFα抗体維持療法の有効性と安全性に関する検討

    研究課題/研究課題番号:15K10133  2015年4月 - 2019年3月

    科学研究費助成事業  基盤研究(C)

    中山 吾郎, 藤井 努, 小寺 泰弘

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    担当区分:研究代表者 

    配分額:3900000円 ( 直接経費:3000000円 、 間接経費:900000円 )

    クローン病の腸管病変に対する術後抗TNF-α抗体薬(アダリムマブ)維持療法の再発抑制効果を明らかにする目的で臨床研究を実施した.26例を対象とし,術後8週以内にアダリムマブを導入し,その有効性と安全性について検討を行った.主要評価項目である術後1年の内視鏡的吻合部再発率は31%であった.また,術後1年の臨床的再発率は17%で,再手術を必要とする症例は認めなった.再発リスク因子に関する解析では,術前の抗TNF-α抗体薬の使用,特にアダリムマブの治療歴を有することが独立した再発リスク因子であった.今後,再発リスクとなる症例群を対象とした新たな術後治療に関する臨床研究を計画中である.
    クローン病の術後寛解維持療法としてアダリムマブの有効性を検討した国内初めての前方視的臨床研究であり,術後再発を抑制するための新たな治療戦略を示唆する成果であると考える.