Updated on 2024/09/19

写真a

 
NAKAYAMA Goro
 
Organization
Graduate School of Medicine Program in Integrated Medicine Musculoskeletal and Cutaneous Medicine Associate professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Associate professor

Degree 1

  1. 医学博士 ( 2007.11   名古屋大学 ) 

Research Interests 2

  1. 大腸癌に対する外科的治療

  2. 炎症性腸疾患に対する外科治療

Research Areas 1

  1. Others / Others  / Digestive Organ Surgery

Professional Memberships 4

  1. 日本内視鏡外科学会   技術認定医

  2. 制癌剤適応研究会   幹事

  3. 大腸癌研究会   施設代表者,世話人

  4. 日本ロボット外科学会   認定医

Committee Memberships 1

  1. 名古屋大学医学部附属病院IRB   専門分野委員(外科系)  

    2015.4   

 

Papers 145

  1. Catheter-related bloodstream infection caused by Lacticaseibacillus paracasei: A case report and literature review

    Fukuda, Y; Morioka, H; Yamamoto, S; Iguchi, M; Umeda, S; Asahara, T; Kanda, K; Oka, K; Nakayama, G; Yagi, T

    JOURNAL OF INFECTION AND CHEMOTHERAPY   Vol. 30 ( 7 ) page: 664 - 667   2024.7

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  2. Prognostic Impact of CDKN2A Mutations Associated With Smoking and Drinking History in Japanese Digestive Cancers.

    Fujita K, Hayashi M, Nakagawa N, Kurimoto K, Inokawa Y, Takami H, Nakanishi K, Umeda S, Shimizu D, Hattori N, Kanda M, Tanaka C, Nakayama G, Kodera Y

    Anticancer research   Vol. 44 ( 6 ) page: 2699 - 2707   2024.6

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    Language:English  

    DOI: 10.21873/anticanres.17077

    PubMed

  3. Outcomes of surgical treatment for enterovesical fistula in Crohn's disease.

    Hattori N, Nakayama G, Umeda S, Nakamura M, Yamamura T, Sawada T, Nakanishi K, Shimizu D, Kanda M, Hayashi M, Tanaka C, Kodera Y

    Nagoya journal of medical science   Vol. 86 ( 2 ) page: 280 - 291   2024.5

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    Language:English  

    DOI: 10.18999/nagjms.86.2.280

    PubMed

  4. Killer cell lectin-like receptor G2 facilitates aggressive phenotypes of gastric cancer cells via dual activation of the ERK1/2 and JAK/STAT pathways

    Ito, Y; Kanda, M; Sasahara, M; Tanaka, C; Shimizu, D; Umeda, S; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Kodera, Y

    GASTRIC CANCER   Vol. 27 ( 3 ) page: 506 - 518   2024.5

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  5. Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth <i>via</i> BCL-2-mediated intrinsic apoptosis

    Sasahara, M; Kanda, M; Tanaka, C; Shimizu, D; Umeda, S; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Kodera, Y

    INTERNATIONAL JOURNAL OF CANCER   Vol. 154 ( 7 ) page: 1272 - 1284   2024.4

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  6. Risk Factors for Long-term Body Weight Loss After Proximal Gastrectomy: A Retrospective Analysis

    Agatsuma, Y; Nakanishi, K; Tanaka, C; Kanda, M; Shimizu, D; Umeda, S; Kurimoto, K; Inokawa, Y; Takami, H; Hattori, N; Hayashi, M; Nakayama, G; Fujiwara, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 44 ( 4 ) page: 1645 - 1651   2024.4

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  7. ASO Visual Abstract: Absence of Hypercoagulation Status After Neoadjuvant Treatment is Associated with Favorable Prognosis in Patients Undergoing Subtotal Esophagectomy for Esophageal Squamous Cell Carcinoma

    Sugiyama, F; Kanda, M; Shimizu, D; Umeda, S; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY     2024.2

  8. Absence of Hypercoagulation Status after Neoadjuvant Treatment is Associated with Favorable Prognosis in Patients Undergoing Subtotal Esophagectomy for Esophageal Squamous Cell Carcinoma

    Sugiyama, F; Kanda, M; Shimizu, D; Umeda, S; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 31 ( 5 ) page: 3417 - 3425   2024.1

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  9. Increased STX3 transcript and protein levels were associated with poor prognosis in two independent cohorts of esophageal squamous cell carcinoma patients

    Shinozuka, T; Kanda, M; Sato, Y; Shimizu, D; Tanaka, C; Umeda, S; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Kodera, Y

    CANCER MEDICINE   Vol. 12 ( 24 ) page: 22185 - 22195   2023.12

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  10. Predictive impacts of peritoneal washing cytology for surgical resection-intended pancreatic cancer cases: Establishment of planned staging laparoscopy criteria

    Tanaka, N; Takami, H; Hayashi, M; Inokawa, Y; Kurimoto, K; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Kodera, Y

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 30 ( 11 ) page: 1273 - 1281   2023.11

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  11. Risk Stratification by Tissue<i> GAD1</i> Expression Level in Curatively Resected Esophageal Squamous Cell Carcinoma

    Kishida, T; Kanda, M; Sato, Y; Shimizu, D; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    CANCER GENOMICS & PROTEOMICS   Vol. 20 ( 6 ) page: 617 - 625   2023.11

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  12. Identification of stromal cell-derived factor 4 as a liquid biopsy-based diagnostic marker in solid cancers

    Shinozuka, T; Kanda, M; Shimizu, D; Umeda, S; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    SCIENTIFIC REPORTS   Vol. 13 ( 1 ) page: 15540   2023.9

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  13. A proposed new Japanese classification of synchronous peritoneal metastases from colorectal cancer: A multi-institutional, prospective, observational study conducted by the Japanese Society for Cancer of the Colon and Rectum

    Kobayashi, H; Kotake, K; Kawasaki, M; Kanemitsu, Y; Kinugasa, Y; Ueno, H; Maeda, K; Suto, T; Itabashi, M; Funahashi, K; Ozawa, H; Koyama, F; Noura, S; Ishida, H; Ohue, M; Kiyomatsu, T; Ishihara, S; Koda, K; Baba, H; Kawada, K; Hashiguchi, Y; Goi, T; Toiyama, Y; Tomita, N; Sunami, E; Akagi, Y; Watanabe, J; Hakamada, K; Nakayama, G; Sugihara, K; Ajioka, Y

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 7 ( 5 ) page: 765 - 771   2023.9

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  14. The preoperative systemic immune-inflammation index is associated with an unfavorable prognosis for patients undergoing curative resection of esophageal squamous cell carcinoma after neoadjuvant therapy

    Obata, Y; Kanda, M; Shimizu, D; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    SURGERY TODAY   Vol. 53 ( 8 ) page: 964 - 972   2023.8

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  15. High Preoperative Platelet to Lymphocyte Ratio is Associated with a Greater Risk of Postoperative Complications and Hematogenous Recurrences in Esophageal Squamous Cell Carcinoma Patients Receiving Neoadjuvant Treatment

    Sasahara, M; Kanda, M; Shimizu, D; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Fujiwara, M; Nakayama, G; Kodera, Y

    DIGESTIVE SURGERY   Vol. 40 ( 1-2 ) page: 48 - 57   2023.7

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  16. High Preoperative Serum D-dimer Predicts Unfavorable Survival Outcomes for Pancreatic Cancer Patients

    Otsu, T; Hayashi, M; Takami, H; Inokawa, Y; Tanaka, N; Kurimoto, K; Nakanishi, K; Umeda, S; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Kodera, Y

    ANTICANCER RESEARCH   Vol. 43 ( 7 ) page: 3173 - 3181   2023.7

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  17. Optimal molecular-targeted therapies as first-line treatment for <i>RAS</i> wild-type, right-sided metastatic colorectal cancer from the Analysis and Research in Cancers of the Digestive System (ARCAD) database

    Yamazaki, K; Takeda, Y; Misumi, T; Suzuki, M; Wakabayashi, M; Bando, H; Oki, E; Douillard, JY; Punt, CJA; Van Cutsem, E; Bokemeyer, C; Venook, AP; Maehara, Y; Heinemann, V; Cremolini, C; Nakayama, G; Andre, T; Shi, Q; De Gramont, A; Yoshino, T

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 41 ( 16 )   2023.6

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  18. Albumin-Globulin Ratio Indicates the Survival Outcome of Pancreatic Cancer Cases Who Underwent Preoperative Treatment and Curative Surgical Resection

    Hayashi, M; Kobayashi, D; Takami, H; Inokawa, Y; Tanaka, N; Kurimoto, K; Nakanishi, K; Umeda, S; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Kodera, Y

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   Vol. 75 ( 5 ) page: 1330 - 1339   2023.5

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  19. Molecular genetic positioning of small intestine and papilla of Vater carcinomas including clinicopathological classification

    Nakamura, M; Okamura, Y; Ohshima, K; Sugiura, T; Ashida, R; Ohgi, K; Bando, E; Fujiya, K; Shiomi, A; Kagawa, H; Imamura, T; Nakayama, G; Kodera, Y; Uesaka, K; Ohike, N; Norose, T; Sasaki, K; Sugino, T; Ohnami, S; Nagashima, T; Urakami, K; Akiyama, Y; Yamaguchi, K

    CANCER MEDICINE   Vol. 12 ( 10 ) page: 11491 - 11502   2023.5

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  20. Impact of obstructive ventilatory impairment on intraoperative bleeding during laparoscopic hepatectomy

    Nakamura, M; Okamura, Y; Sugiura, T; Ashida, R; Ohgi, K; Yamada, M; Otsuka, S; Nakayama, G; Kodera, Y; Uesaka, K

    LANGENBECKS ARCHIVES OF SURGERY   Vol. 408 ( 1 ) page: 122   2023.3

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  21. Perioperative changes in geriatric functions of elderly patients undergoing surgical resection for gastric cancer.

    Tanaka, C; Kanda, M; Nakanishi, K; Umeda, S; Shimizu, D; Inokawa, Y; Takami, H; Hayashi, M; Nakayama, G; Fujiwara, M; Kodera, Y; Hattori, N

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 41   page: 811 - 811   2023.2

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  22. Proposal of a coagulation score to predict postoperative survival of patients undergoing neoadjuvant therapy followed by subtotal esophagectomy for squamous cell carcinoma of the esophagus.

    Sugiyama, F; Shimizu, D; Kanda, M; Tanaka, C; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 41   page: 448 - 448   2023.2

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  23. Controlling Nutritional Status Score Serves as a Prognosticator in Esophageal Squamous Cell Carcinoma: Optimal Timing of Evaluation of Patients Undergoing Neoadjuvant Treatment

    Nonogaki, I; Kanda, M; Shimizu, D; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Koike, M; Nakayama, G; Kodera, Y

    WORLD JOURNAL OF SURGERY   Vol. 47 ( 1 ) page: 217 - 226   2023.1

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  24. The effects of ustekinumab on small intestinal lesions and stenotic lesions

    Wada, H; Murate, K; Nakamura, M; Furukawa, K; Kakushima, N; Yamamura, T; Maeda, K; Sawada, T; Ishikawa, E; Ishikawa, T; Ohno, E; Honda, T; Kawashima, H; Nakayama, G; Hattori, N; Umeda, S; Ishigami, M

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 84 ( 4 ) page: 825 - 838   2022.11

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  25. ASO Visual Abstract: Downregulation of ROBO4 in Pancreatic Cancer Serves as a Biomarker of Poor Prognosis and Indicates Increased Cell Motility and Proliferation Through Activation of MMP-9

    Yamanaka, M; Hayashi, M; Sonohara, F; Yamada, S; Tanaka, H; Sakai, A; Mii, S; Kobayashi, D; Kurimoto, K; Tanaka, N; Inokawa, Y; Takami, H; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 29 ( 11 ) page: 7192 - 7193   2022.10

  26. Downregulation of ROBO4 in Pancreatic Cancer Serves as a Biomarker of Poor Prognosis and Indicates Increased Cell Motility and Proliferation Through Activation of MMP-9

    Yamanaka, M; Hayashi, M; Sonohara, F; Yamada, S; Tanaka, H; Sakai, A; Mii, S; Kobayashi, D; Kurimoto, K; Tanaka, N; Inokawa, Y; Takami, H; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 29 ( 11 ) page: 7180 - 7189   2022.10

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  27. Transcriptomic profiling on localized gastric cancer identified <i>CPLX1</i> as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy

    Tanaka, H; Kanda, M; Shimizu, D; Tanaka, C; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Kodera, Y

    JOURNAL OF GASTROENTEROLOGY   Vol. 57 ( 9 ) page: 640 - 653   2022.9

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  28. Comparison Between FOLFIRINOX and nal-IRI/FL as Second-line Treatment After Gemcitabine Plus Nab-paclitaxel for Pancreatic Cancer br

    Otsu, T; Inokawa, Y; Takami, H; Hayashi, M; Kurimoto, K; Tanaka, N; Tanaka, H; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Kodera, Y

    ANTICANCER RESEARCH   Vol. 42 ( 8 ) page: 3889 - 3894   2022.8

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  29. Expression of cellular retinoic acid binding protein 1 predicts peritoneal recurrence of gastric cancer

    Sakata, K; Kanda, M; Shimizu, D; Nakamura, S; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    INTERNATIONAL JOURNAL OF ONCOLOGY   Vol. 60 ( 6 )   2022.6

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  30. Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells

    Umeda, S; Kanda, M; Shimizu, D; Nakamura, S; Sawaki, K; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Kodera, Y

    GASTRIC CANCER   Vol. 25 ( 3 ) page: 558 - 572   2022.5

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  31. Direct Observation of Retinal Microvessels in Cancer Patients After Systemic Administration of Bevacizumab and Oxaliplatin.

    Mitsuma A, Ito Y, Shimokata T, Tanaka C, Uehara K, Nakayama G, Terasaki H, Ando Y

    Cancer diagnosis & prognosis   Vol. 2 ( 3 ) page: 330 - 335   2022.5

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    Language:English  

    DOI: 10.21873/cdp.10113

    PubMed

  32. Drain Amylase Concentrations at 3 h After Gastrectomy Enhance Early Prediction of Postoperative Peripancreatic Inflammatory Fluid Collection

    Nakanishi, K; Kanda, M; Tanaka, C; Takeda, S; Tanaka, K; Shimizu, D; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Fujiwara, M; Kodera, Y

    WORLD JOURNAL OF SURGERY   Vol. 46 ( 3 ) page: 648 - 655   2022.3

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  33. Neoadjuvant docetaxel, oxaliplatin plus S-1 for treating clinical stage III squamous cell carcinoma of the esophagus: Study protocol of an open-label phase II trial

    Kanda, M; Shimizu, D; Miyata, K; Maeda, O; Tanaka, C; Inokawa, Y; Hattori, N; Hayashi, M; Ando, M; Kuwatsuka, Y; Murotani, K; Nakayama, G; Koike, M; Ando, Y; Ebata, T; Kodera, Y

    CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS   Vol. 24   page: 100853   2021.12

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  34. The significance of the time to arterial perfusion in intraoperative ICG angiography during colorectal surgery

    Aiba, T; Uehara, K; Ogura, A; Tanaka, A; Yonekawa, Y; Hattori, N; Nakayama, G; Kodera, Y; Ebata, T; Nagino, M

    SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES   Vol. 35 ( 12 ) page: 7227 - 7235   2021.12

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  35. Impact of molecular surgical margin analysis on the prediction of pancreatic cancer recurrences after pancreaticoduodenectomy

    Sunagawa, Y; Hayashi, M; Yamada, S; Tanabe, H; Kurimoto, K; Tanaka, N; Sonohara, F; Inokawa, Y; Takami, H; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    CLINICAL EPIGENETICS   Vol. 13 ( 1 ) page: 172   2021.12

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  36. Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells

    Kanda, M; Shimizu, D; Nakamura, S; Sawaki, K; Umeda, S; Miwa, T; Tanaka, H; Inokawa, Y; Hattori, N; Hayashi, M; Tanaka, C; Nakayama, G; Iguchi, Y; Katsuno, M; Kodera, Y

    ONCOGENE   Vol. 40 ( 36 ) page: 5495 - 5504   2021.9

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  37. A Possible Definition of Oligometastasis in Pancreatic Cancer and Associated Survival Outcomes

    Yamanaka, M; Hayashi, M; Yamada, S; Sonohara, F; Takami, H; Inokawa, Y; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 41 ( 8 ) page: 3933 - 3940   2021.8

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  38. G-protein subunit gamma-4 expression has potential for detection, prediction and therapeutic targeting in liver metastasis of gastric cancer

    Tanaka, H; Kanda, M; Miwa, T; Umeda, S; Sawaki, K; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y

    BRITISH JOURNAL OF CANCER   Vol. 125 ( 2 ) page: 220 - 228   2021.7

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  39. High Serum Uric Acid Levels Could Be a Risk Factor of Hepatocellular Carcinoma Recurrences

    Hayashi, M; Yamada, S; Tanabe, H; Takami, H; Inokawa, Y; Sonohara, F; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL   Vol. 73 ( 6 ) page: 996 - 1003   2021.7

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  40. Novel prognostic implications of YTH domain family 2 in resected hepatocellular carcinoma

    Nakagawa, N; Sonohara, F; Tanaka, K; Sunagawa, Y; Inokawa, Y; Takami, H; Hayashi, M; Yamada, S; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ONCOLOGY LETTERS   Vol. 22 ( 1 ) page: 538   2021.7

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  41. The carcinoembryonic antigen ratio is a potential predictor of survival in recurrent colorectal cancer

    Suzuki, Y; Ogura, A; Uehara, K; Aiba, T; Ohara, N; Murata, Y; Jinno, T; Mishina, T; Sato, Y; Hattori, N; Nakayama, G; Kodera, Y; Ebata, T

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 26 ( 7 ) page: 1264 - 1271   2021.7

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  42. <i>miR</i>-<i>23b</i>-<i>3p</i> Plays an Oncogenic Role in Hepatocellular Carcinoma

    Hayashi, M; Yamada, S; Kurimoto, K; Tanabe, H; Hirabayashi, S; Sonohara, F; Inokawa, Y; Takami, H; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 6 ) page: 3416 - 3426   2021.6

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  43. Indications for neoadjuvant treatment based on risk factors for poor prognosis before and after neoadjuvant chemotherapy alone in patients with locally advanced rectal cancer

    Ogura, A; Uehara, K; Aiba, T; Sando, M; Tanaka, A; Ohara, N; Murata, Y; Sato, Y; Hattori, N; Nakayama, G; Ebata, T; Kodera, Y; Nagino, M

    EJSO   Vol. 47 ( 5 ) page: 1005 - 1011   2021.5

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  44. Different Characteristics of Serum Alfa Fetoprotein and Serum Des-gamma-carboxy Prothrombin in Resected Hepatocellular Carcinoma

    Hayashi, M; Yamada, S; Takano, N; Okamura, Y; Takami, H; Inokawa, Y; Sonohara, F; Tanaka, N; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    IN VIVO   Vol. 35 ( 3 ) page: 1749 - 1760   2021.5

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  45. Hepatic metastasis of gastric cancer is associated with enhanced expression of ethanolamine kinase 2 via the p53-Bcl-2 intrinsic apoptosis pathway

    Miwa, T; Kanda, M; Shimizu, D; Umeda, S; Sawaki, K; Tanaka, H; Tanaka, C; Hattori, N; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y

    BRITISH JOURNAL OF CANCER   Vol. 124 ( 8 ) page: 1449 - 1460   2021.4

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  46. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma

    Suenaga, M; Fujii, T; Yamada, S; Hayashi, M; Shinjo, K; Takami, H; Niwa, Y; Sonohara, F; Shimizu, D; Kanda, M; Kobayashi, D; Tanaka, C; Nakayama, G; Koike, M; Fujiwara, M; Kondo, Y; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 4 ) page: 2277 - 2286   2021.4

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  47. Genome-wide identification and characterization of circular RNA in resected hepatocellular carcinoma and background liver tissue

    Sunagawa, Y; Yamada, S; Sonohara, F; Kurimoto, K; Tanaka, N; Suzuki, Y; Inokawa, Y; Takami, H; Hayashi, M; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    SCIENTIFIC REPORTS   Vol. 11 ( 1 ) page: 6016   2021.3

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  48. Tissue <i>RNFT2</i> Expression Levels Are Associated With Peritoneal Recurrence and Poor Prognosis in Gastric Cancer

    Sasahara, M; Kanda, M; Shimizu, D; Tanaka, C; Inokawa, Y; Hattori, N; Hayashi, M; Nakayama, G; Kodera, Y

    ANTICANCER RESEARCH   Vol. 41 ( 2 ) page: 609 - 617   2021.2

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  49. Randomised phase II trial of capecitabine plus oxaliplatin with continuous versus intermittent use of oxaliplatin as adjuvant chemotherapy for stage II/III colon cancer (CCOG-1302 study)

    Nakayama, G; Takano, N; Taniguchi, H; Ishigure, K; Yokoyama, H; Teramoto, H; Hashimoto, R; Sakai, M; Ishiyama, A; Kinoshita, T; Hayashi, N; Nakamura, M; Hattori, N; Sato, Y; Umeda, S; Uehara, K; Aiba, T; Sonohara, F; Hayashi, M; Kanda, M; Kobayashi, D; Tanaka, C; Yamada, S; Koike, M; Fujiwara, M; Murotani, K; Ando, M; Ando, Y; Muro, K; Kodera, Y

    EUROPEAN JOURNAL OF CANCER   Vol. 144   page: 61 - 71   2021.2

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  50. Function and prognostic value of melanoma-associated antigen-D4 protein in esophageal squamous cell carcinoma

    Sawaki, K; Kanda, M; Sato, Y; Shimizu, D; Uno, Y; Umeda, S; Hattori, N; Hayashi, M; Tanaka, C; Yamada, S; Nakayama, G; Motoyama, S; Koike, M; Fujiwara, M; Kodera, Y

    CANCER SCIENCE   Vol. 112   page: 531 - 531   2021.2

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    Language:Japanese  

    Web of Science

  51. Development of novel combination cancer immunotherapy using anti-PD-1 and anti-PD-L1 antibody

    Hasegawa, H; Sugiyama, D; Kanda, M; Hayashi, M; Tanaka, C; Yamada, S; Nakayama, G; Koike, M; Nomoto, S; Fujiwara, M; Kodera, Y; Nishikawa, H

    CANCER SCIENCE   Vol. 112   page: 741 - 741   2021.2

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    Language:Japanese  

    Web of Science

  52. Randomized phase II study comparing the efficacy and safety of SOX versus mFOLFOX6 as neoadjuvant chemotherapy without radiotherapy for locally advanced rectal cancer (KSCC1301)

    Miwa, K; Oki, E; Enomoto, M; Ihara, K; Ando, K; Fujita, F; Tominaga, M; Mori, S; Nakayama, G; Shimokawa, M; Saeki, H; Baba, H; Mori, M; Akagi, Y

    BMC CANCER   Vol. 21 ( 1 ) page: 23   2021.1

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  53. Perioperative assessment of indocyanine green elimination rate accurately predicts postoperative liver failure in patients undergoing hepatectomy

    Sunagawa, Y; Yamada, S; Kato, Y; Sonohara, F; Takami, H; Inokawa, Y; Hayashi, M; Nakayama, G; Koike, M; Kodera, Y

    JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES   Vol. 28 ( 1 ) page: 86 - 94   2021.1

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  54. Pancreatic Fat and Body Composition Measurements by Computed Tomography are Associated with Pancreatic Fistula After Pancreatectomy

    Tanaka, K; Yamada, S; Sonohara, F; Takami, H; Hayashi, M; Kanda, M; Kobayashi, D; Tanaka, C; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 28 ( 1 ) page: 530 - 538   2021.1

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  55. Age-Related Differences in the Prognosis of Pancreatic Cancer According to Perioperative Systemic Therapy

    Sonohara, F; Yamada, S; Kurimoto, K; Inokawa, Y; Takami, H; Hayashi, M; Shimizu, D; Hattori, N; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Fujii, T; Kodera, Y

    PANCREAS   Vol. 50 ( 1 ) page: 37 - 46   2021.1

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  56. Novel Prognostic Implications of Methylated RNA and Demethylases in Resected HCC and Background Liver Tissue

    Nakagawa, N; Tanaka, K; Sonohara, F; Kandimalla, R; Sunagawa, Y; Inokawa, Y; Takami, H; Hayashi, M; Yamada, S; Kanda, M; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6665 - 6676   2020.12

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  57. AMIGO2 Expression as a Potential Prognostic Biomarker for Gastric Cancer

    Nakamura, S; Kanda, M; Shimizu, D; Tanaka, C; Inokawa, Y; Hattori, N; Hayashi, M; Yamada, S; Nakayama, G; Omae, K; Koike, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 40 ( 12 ) page: 6713 - 6721   2020.12

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  58. What is the impact of systemic chemotherapy for lateral lymph nodes in patients with locally advanced low rectal cancer?

    Ogura, A; Uehara, K; Aiba, T; Hattori, N; Nakayama, G; Maeda, O; Ando, Y; Kodera, Y; Ebata, T; Nagino, M

    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE   Vol. 35 ( 11 ) page: 2073 - 2080   2020.11

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  59. Correlation Between the Metabolic Conversion of a Capecitabine Metabolite, 5′-Deoxy-5-fluorocytidine, and Creatinine Clearance

    Inaishi, T; Fujita, KI; Matsumoto, N; Shimokata, T; Maeda, O; Kikumori, T; Hattori, N; Nakayama, G; Ando, Y

    IN VIVO   Vol. 34 ( 6 ) page: 3539 - 3544   2020.11

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  60. AnOpen-Label Single-ArmPhaseIIStudy of Treatment with Neoadjuvant S-1 Plus Cisplatin for Clinical StageIIISquamous Cell Carcinoma of the Esophagus

    Kanda, M; Koike, M; Iwata, N; Shimizu, D; Tanaka, C; Hattori, N; Hayashi, M; Yamada, S; Omae, K; Nakayama, G; Kodera, Y

    ONCOLOGIST   Vol. 25 ( 11 ) page: E1650 - E1654   2020.11

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  61. Characteristics Associated with Nodal and Distant Recurrence after Curative Resection of Squamous Cell Carcinoma of the Thoracic Esophagus

    Kanda, M; Koike, M; Shimizu, D; Tanaka, C; Hayashi, M; Hattori, N; Yamada, S; Nakayama, G; Fujiwara, M; Kodera, Y

    JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS   Vol. 231 ( 4 ) page: E121 - E121   2020.10

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  62. An outcome analysis of predictive factors for portal or splenic vein thrombosis after distal pancreatectomy

    Tanaka, N; Yamada, S; Sonohara, F; Takami, H; Hayashi, M; Nakayama, G; Koike, M; Fujiwara, M; Fujii, T; Kodera, Y

    SURGERY TODAY   Vol. 50 ( 10 ) page: 1282 - 1289   2020.10

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  63. STRA6 Expression Serves as a Prognostic Biomarker of Gastric Cancer

    Nakamura, S; Kanda, M; Shimizu, D; Sawaki, K; Tanaka, C; Hattori, N; Hayashi, M; Yamada, S; Nakayama, G; Omae, K; Koike, M; Kodera, Y

    CANCER GENOMICS & PROTEOMICS   Vol. 17 ( 5 ) page: 509 - 516   2020.9

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  64. The impact of cancer stem cell markers in the tissues of pancreatic ductal adenocarcinoma for prognosis after surgical resections

    Inokawa, Y; Yamada, S; Hayashi, M; Sunagawa, Y; Sonohara, F; Takami, H; Hattori, N; Kanda, M; Kobayashi, D; Tanaka, C; Nakayama, G; Koike, M; Kodera, Y

    CANCER RESEARCH   Vol. 80 ( 16 )   2020.8

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  65. Importance of the neoadjuvant rectal (NAR) score to the outcome of neoadjuvant chemotherapy alone for locally advanced rectal cancer

    Mukai, T; Uehara, K; Aiba, T; Ogura, A; Tsuzuki, T; Tanaka, A; Sando, M; Ohara, N; Sato, Y; Hattori, N; Nakayama, G; Kodera, Y; Nagino, M

    SURGERY TODAY   Vol. 50 ( 8 ) page: 912 - 919   2020.8

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  66. Tumor Location Is Associated With the Prevalence of <i>Braf</i> And <i>Pik3ca</i> Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan

    Taniguchi, H; Uehara, K; Nakayama, G; Nakayama, H; Aiba, T; Hattori, N; Kataoka, M; Nakano, Y; Kawase, Y; Okochi, O; Matsuoka, H; Utsunomiya, S; Sakamoto, E; Mori, Y; Umeda, S; Shikano, T; Komori, K; Tajika, M; Kadowaki, S; Muro, K; Yatabe, Y

    TRANSLATIONAL ONCOLOGY   Vol. 13 ( 7 ) page: 100786   2020.7

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  67. Novel Prognostic Implications of DUPAN-2 in the Era of Initial Systemic Therapy for Pancreatic Cancer

    Sunagawa, Y; Yamada, S; Sato, Y; Morimoto, D; Sonohara, F; Takami, H; Inokawa, Y; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujiwara, M; Fujii, T; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 6 ) page: 2081 - 2089   2020.6

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  68. Fraser extracellular matrix complex subunit 1 promotes liver metastasis of gastric cancer

    Umeda, S; Kanda, M; Miwa, T; Tanaka, H; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y

    INTERNATIONAL JOURNAL OF CANCER   Vol. 146 ( 10 ) page: 2865 - 2876   2020.5

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  69. Clinical impact of additional therapy for residual pancreatic cancer

    Yamada, S; Sonohara, F; Tashiro, M; Murotani, K; Takami, H; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujii, T; Kodera, Y

    SURGERY TODAY   Vol. 50 ( 5 ) page: 440 - 448   2020.5

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  70. Characteristics of Lung Metastasis as an Initial Recurrence Pattern After Curative Resection of Pancreatic Cancer

    Morimoto, D; Yamada, S; Sonohara, F; Takami, H; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujiwara, M; Fujii, T; Kodera, Y

    PANCREAS   Vol. 49 ( 5 ) page: 699 - 705   2020.5

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  71. Optimized Cutoff Value of Serum Squamous Cell Carcinoma Antigen Concentration Accurately Predicts Recurrence After Curative Resection of Squamous Cell Carcinoma of the Esophagus

    Kanda, M; Koike, M; Shimizu, D; Tanaka, C; Kobayashi, D; Hattori, N; Hayashi, M; Omae, K; Yamada, S; Nakayama, G; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 4 ) page: 1233 - 1240   2020.4

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  72. Exploration of Exosomal Micro RNA Biomarkers Related to Epithelial-to-Mesenchymal Transition in Pancreatic Cancer

    Sonohara, F; Yamada, S; Takeda, S; Hayashi, M; Suenaga, M; Sunagawa, Y; Tashiro, M; Takami, H; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 40 ( 4 ) page: 1843 - 1853   2020.4

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  73. Clinical Implications of Naples Prognostic Score in Patients with Resected Pancreatic Cancer

    Nakagawa, N; Yamada, S; Sonohara, F; Takami, H; Hayashi, M; Kanda, M; Kobayashi, D; Tanaka, C; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    ANNALS OF SURGICAL ONCOLOGY   Vol. 27 ( 3 ) page: 887 - 895   2020.3

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  74. Randomized phase II trial of CAPOX with continuous versus intermittent use of oxaliplatin as an adjuvant chemotherapy after curative resection of stage II/III colon cancer (CCOG-1302 study)

    Nakamura, M; Nakayama, G; Ishigure, K; Mashita, N; Yokoyama, H; Hattori, N; Uehara, K; Yamada, S; Koike, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 )   2020.2

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  75. Predictive value of the modified systemic inflammation score in patients undergoing curative resection of squamous cell carcinoma of the esophagus

    Kanda, M; Koike, M; Shimizu, D; Tanaka, C; Kobayashi, D; Sonohara, F; Takami, H; Inokawa, Y; Hattori, N; Hayashi, M; Yamada, S; Nakayama, G; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 38 ( 4 )   2020.2

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  76. A prospective trial to evaluate treatment effects of a β-hydroxy-β-methylbutyrate containing nutrient for leakage a the anastomotic site after esophagectomy

    Kanda, M; Koike, M; Fukaya, M; Miyata, K; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Murotani, K; Fujiwara, M; Nagino, M; Kodera, Y

    NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 82 ( 1 ) page: 33 - 37   2020.2

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  77. The Significance of Molecular Biomarkers on Clinical Survival Outcome Differs Depending on Colon Cancer Sidedness

    Hirabayashi, S; Hayashi, M; Nakayama, G; Mii, S; Hattori, N; Tanabe, H; Kanda, M; Tanaka, C; Kobayashi, D; Yamada, S; Koike, M; Fujiwara, M; Takahashi, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 40 ( 1 ) page: 201 - 211   2020.1

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  78. Phase II study of capecitabine plus oxaliplatin (CapOX) as adjuvant chemotherapy for locally advanced rectal cancer (CORONA II)

    Hattori, N; Nakayama, G; Uehara, K; Aiba, T; Ishigure, K; Sakamoto, E; Tojima, Y; Kanda, M; Kobayashi, D; Tanaka, C; Yamada, S; Koike, M; Fujiwara, M; Nagino, M; Kodera, Y

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY   Vol. 25 ( 1 ) page: 118 - 125   2020.1

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  79. Peritoneal Lavage Tumor DNA as a Novel Biomarker for Predicting Peritoneal Recurrence in Pancreatic Ductal Adenocarcinoma

    Suenaga, M; Fujii, T; Yamada, S; Hayashi, M; Shinjo, K; Takami, H; Niwa, Y; Sonohara, F; Shimizu, D; Kanda, M; Kobayashi, D; Tanaka, C; Nakayama, G; Koike, M; Fujiwara, M; Kondo, Y; Kodera, Y

    PANCREAS   Vol. 48 ( 10 ) page: 1528 - 1528   2019.11

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  80. Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer

    Sawaki, K; Kanda, M; Umeda, S; Miwa, T; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Omae, K; Koike, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6125 - 6133   2019.11

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  81. Comparison of non-invasive liver reserve and fibrosis models: Implications for surgery and prognosis for hepatocellular carcinoma

    Sonohara, F; Yamada, S; Tanaka, N; Tashiro, M; Sunagawa, Y; Morimoto, D; Tanaka, H; Takami, H; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    HEPATOLOGY RESEARCH   Vol. 49 ( 11 ) page: 1305 - 1315   2019.11

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  82. Establishment of Peritoneal and Hepatic Metastasis Mouse Xenograft Models Using Gastric Cancer Cell Lines

    Miwa, T; Kanda, M; Umeda, S; Tanaka, H; Shimizu, D; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y

    IN VIVO   Vol. 33 ( 6 ) page: 1785 - 1792   2019.11

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  83. Expression, Function, and Prognostic Value of MAGE-D4 Protein in Esophageal Squamous Cell Carcinoma

    Uno, Y; Kanda, M; Sato, Y; Shimizu, D; Umeda, S; Hattori, N; Hayashi, M; Tanaka, C; Kobayashi, D; Yamada, S; Nakayama, G; Motoyama, S; Koike, M; Kodera, Y

    ANTICANCER RESEARCH   Vol. 39 ( 11 ) page: 6015 - 6023   2019.11

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  84. Feasibility of subtotal esophagectomy with systematic lymphadenectomy in selected elderly patients with esophageal cancer; a propensity score matching analysis

    Kanda, M; Koike, M; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Omae, K; Kodera, Y

    BMC SURGERY   Vol. 19 ( 1 ) page: 143   2019.10

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  85. Randomized phase II trial of CAPOX with planned oxaliplatin stop-and-go strategy as adjuvant chemotherapy after curative resection of colon cancer (CCOG-1302 study)

    Yokoyama, H; Nakayama, G; Ishigure, K; Hayashi, N; Tanaka, K; Tsutsuyama, M; Hattori, N; Yamada, S; Kodera, Y

    ANNALS OF ONCOLOGY   Vol. 30   2019.10

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  86. Novel implications of combined arterial resection for locally advanced pancreatic cancer in the era of newer chemo-regimens

    Sonohara, F; Yamada, S; Takami, H; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Koike, M; Fujiwara, M; Fujii, T; Kodera, Y

    EJSO   Vol. 45 ( 10 ) page: 1895 - 1900   2019.10

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  87. Biological and conditional factors should be included when defining criteria for resectability for patients with pancreatic cancer.

    Kato Y, Yamada S, Tashiro M, Sonohara F, Takami H, Hayashi M, Kanda M, Kobayashi D, Tanaka C, Nakayama G, Koike M, Fujiwara M, Kodera Y

    HPB : the official journal of the International Hepato Pancreato Biliary Association   Vol. 21 ( 9 ) page: 1211 - 1218   2019.9

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    DOI: 10.1016/j.hpb.2019.01.012

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  88. Functions of FRAS1 as a driver gene of liver metastasis from gastric cancer analyzed by the genome editing technology

    Umeda, S; Kanda, M; Tanaka, H; Sonohara, F; Takami, H; Hattori, N; Hayashi, M; Tanaka, C; Kobayashi, D; Yamada, S; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    CANCER RESEARCH   Vol. 79 ( 13 )   2019.7

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  89. Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy

    Miwa, T; Kanda, M; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Kodera, Y

    JOURNAL OF GASTRIC CANCER   Vol. 19 ( 2 ) page: 183 - 192   2019.6

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  90. Homeobox C10 Influences on the Malignant Phenotype of Gastric Cancer Cell Lines and its Elevated Expression Positively Correlates with Recurrence and Poor Survival.

    Miwa T, Kanda M, Umeda S, Tanaka H, Tanaka C, Kobayashi D, Suenaga M, Hayashi M, Yamada S, Nakayama G, Koike M, Kodera Y

    Annals of surgical oncology   Vol. 26 ( 5 ) page: 1535 - 1543   2019.5

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    DOI: 10.1245/s10434-019-07166-5

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  91. Neoadjuvant CAPOX and bevacizumab alone for locally advanced rectal cancer: long-term results from the N-SOG 03 trial.

    Tomida A, Uehara K, Hiramatsu K, Maeda A, Sakamoto E, Okada Y, Kurumiya Y, Nakayama G, Nakamura M, Aiba T, Nagino M, Of the Nagoya Surgical Oncology Group.

    International journal of clinical oncology   Vol. 24 ( 4 ) page: 403 - 410   2019.4

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    DOI: 10.1007/s10147-018-1372-6

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  92. Increased Expression of DNAJC12 is Associated with Aggressive Phenotype of Gastric Cancer

    Uno Yasuo, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 26 ( 3 ) page: 836 - 844   2019.3

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    DOI: 10.1245/s10434-018-07149-y

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  93. Prediction of peritoneal recurrences of gastric cancer by qPCR analysis of peritoneal lavage fluids.

    Nakanishi, K; Kanda, M; Umeda, S; Tanaka, C; Kobayashi, D; Hayashi, M; Yamada, S; Nakayama, G; Koike, M; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 37 ( 4 )   2019.2

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  94. Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

    Niwa Yukiko, Yamada Suguru, Sonohara Fuminori, Kurimoto Keisuke, Hayashi Masamichi, Tashiro Mitsuru, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF TRANSLATIONAL MEDICINE   Vol. 17 ( 1 ) page: 1   2019.1

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    DOI: 10.1186/s12967-018-1762-6

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  95. Perioperative and prognostic implication of albumin-bilirubin-TNM score in Child-Pugh class A hepatocellular carcinoma

    Sonohara Fuminori, Yamada Suguru, Tanaka Nobutake, Suenaga Masaya, Takami Hideki, Hayashi Masamichi, Niwa Yukiko, Sugimoto Hiroyuki, Hattori Norifumi, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF GASTROENTEROLOGICAL SURGERY   Vol. 3 ( 1 ) page: 65 - 74   2019.1

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    DOI: 10.1002/ags3.12212

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  96. A New Biomarker for Peritoneal Lavage Using Digital PCR in Patients with Pancreatic Ductal Adenocarcinoma

    Suenaga Masaya, Yamada Suguru, Hayashi Masamichi, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 650 - 650   2018.12

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  97. Copine 5 expression predicts prognosis following curative resection of esophageal squamous cell carcinoma

    Umeda Shinichi, Kanda Mitsuro, Koike Masahiko, Tanaka Haruyoshi, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 40 ( 6 ) page: 3772 - 3780   2018.12

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    DOI: 10.3892/or.2018.6742

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  98. Troponin I2 as a specific biomarker for prediction of peritoneal metastasis in gastric cancer

    Sawaki Koichi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 765 - 765   2018.12

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  99. Pattern-specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Suenaga Masaya, Hayashi Masamichi, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128 - 1128   2018.12

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  100. Integrated multigene expression panel to prognosticate patients with gastric cancer

    Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Hayashi Masamichi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 769 - 769   2018.12

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  101. FRAS1 expression reflects the malignancy potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Tanaka Chie, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 1128 - 1128   2018.12

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  102. Prognostic Impact of Portal System Invasion in Pancreatic Cancer Based on Image Classification

    Morimoto Daishi, Yamada Suguru, Murotani Kenta, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tashiro Mitsuru, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 10 ) page: 1350 - 1356   2018.11

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    DOI: 10.1097/MPA.0000000000001186

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  103. Treatment strategy of intraperitoneal and systemic chemotherapy combined with gastrectomy for gastric cancer with peritoneal metastasis

    Kobayashi Daisuke, Kanda Mitsuro, Tanaka Chie, Sonohara Fuminori, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   Vol. 33   page: 98 - 98   2018.11

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  104. Transanal extended rectal surgery with lateral pelvic lymph node dissection

    Aiba T., Uehara K., Mukai T., Hattori N., Nakayama G., Nagino M.

    TECHNIQUES IN COLOPROCTOLOGY   Vol. 22 ( 11 ) page: 893 - 894   2018.11

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    DOI: 10.1007/s10151-018-1891-1

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  105. Clinical Impact of Neoadjuvant Therapy on Nutritional Status in Pancreatic Cancer

    Tashiro Mitsuru, Yamada Suguru, Sonohara Fuminori, Takami Hideki, Suenaga Masaya, Hayashi Masamichi, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 11 ) page: 3365 - 3371   2018.10

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    DOI: 10.1245/s10434-018-6699-8

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  106. Expression of sushi domain containing two reflects the malignant potential of gastric cancer

    Umeda Shinichi, Kanda Mitsuro, Miwa Takashi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 10 ) page: 5194 - 5204   2018.10

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    DOI: 10.1002/cam4.1793

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  107. A longitudinal study of a new point-of-care nerve conduction device for quantitative assessment of chemotherapy-induced peripheral neurotoxicity

    Matsuoka, A; Maeda, O; Mitsuma, A; Uehara, K; Nakayama, G; Nagino, M; Kodera, Y; Ando, Y

    ANNALS OF ONCOLOGY   Vol. 29   2018.10

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  108. Comparison of the Survival Outcomes of Pancreatic Cancer and Intraductal Papillary Mucinous Neoplasms.

    Yamada S, Fujii T, Hirakawa A, Takami H, Suenaga M, Hayashi M, Niwa Y, Hattori N, Iwata N, Kanda M, Tanaka C, Kobayashi D, Nakayama G, Koike M, Fujiwara M, Kodera Y

    Pancreas   Vol. 47 ( 8 ) page: 974 - 979   2018.9

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    DOI: 10.1097/MPA.0000000000001110

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  109. Pattern-Specific Transcriptomics Identifies ASGR2 as a Predictor of Hematogenous Recurrence of Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Miwa Takashi, Tanaka Chie, Kobayashi Daisuke, Umeda Shinichi, Shibata Masahiro, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    MOLECULAR CANCER RESEARCH   Vol. 16 ( 9 ) page: 1420 - 1429   2018.9

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    DOI: 10.1158/1541-7786.MCR-17-0467

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  110. Impact of the Controlling Nutritional Status Score on the Prognosis After Curative Resection of Pancreatic Ductal Adenocarcinoma

    Kato Yoshiyasu, Yamada Suguru, Suenaga Masaya, Takami Hideki, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    PANCREAS   Vol. 47 ( 7 ) page: 823 - 829   2018.8

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    DOI: 10.1097/MPA.0000000000001105

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  111. Randomized Phase II Trial of CapOX plus Bevacizumab and CapIRI plus Bevacizumab as First-Line Treatment for Japanese Patients with Metastatic Colorectal Cancer (CCOG-1201 Study)

    Nakayama Goro, Mitsuma Ayako, Sunagawa Yuki, Ishigure Kiyoshi, Yokoyama Hiroyuki, Matsui Takanori, Nakayama Hiroshi, Nakata Kazuhiko, Ishiyama Akiharu, Asada Takahiro, Umeda Shinichi, Ezaka Kazuhiro, Hattori Norifumi, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    ONCOLOGIST   Vol. 23 ( 8 ) page: 919 - 927   2018.8

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    DOI: 10.1634/theoncologist.2017-0640

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  112. Troponin I2 as a Specific Biomarker for Prediction of Peritoneal Metastasis in Gastric Cancer

    Sawaki Koichi, Kanda Mitsuro, Miwa Takashi, Umeda Shinichi, Tanaka Haruyoshi, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Hattori Norifumi, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 25 ( 7 ) page: 2083 - 2090   2018.7

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    DOI: 10.1245/s10434-018-6480-z

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  113. Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer

    Tanaka Nobutake, Yamada Suguru, Sonohara Fuminori, Suenaga Masaya, Hayashi Masamichi, Takami Hideki, Niwa Yukiko, Hattori Norifumi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page: 9846   2018.6

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    DOI: 10.1038/s41598-018-28253-9

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  114. A Multicenter Clinical Phase II Study of FOLFOXIRI Plus Bevacizumab as First-line Therapy in Patients With Metastatic Colorectal Cancer: QUATTRO Study

    Oki Eiji, Kato Takeshi, Bando Hideaki, Yoshino Takayuki, Muro Kei, Taniguchi Hiroya, Kagawa Yoshinori, Yamazaki Kentaro, Yamaguchi Tatsuro, Tsuji Akihito, Iwamoto Shigeyoshi, Nakayama Goro, Emi Yasunori, Touyama Tetsuo, Nakamura Masato, Kotaka Masahito, Sakisaka Hideki, Yamanaka Takeharu, Kanazawa Akiyoshi

    CLINICAL COLORECTAL CANCER   Vol. 17 ( 2 ) page: 147 - 155   2018.6

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    DOI: 10.1016/j.clcc.2018.01.011

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  115. A novel dual-marker expression panel for easy and accurate risk stratification of patients with gastric cancer

    Kanda Mitsuro, Murotani Kenta, Tanaka Haruyoshi, Miwa Takashi, Umeda Shinichi, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Hattori Norifumi, Suenaga Masaya, Yamada Suguru, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER MEDICINE   Vol. 7 ( 6 ) page: 2463 - 2471   2018.6

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    DOI: 10.1002/cam4.1522

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  116. IDENTIFICATION OF MOLECULES DRIVING HEPATIC METASTASIS FORMATION OF GASTRIC CANCER CELLS

    Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Suenaga Masaya, Takami Hideki, Hattori Norifumi, Niwa Yukiko, Hayashi Masamichi, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    GUT   Vol. 67   page: A5 - A5   2018.6

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    DOI: 10.1136/gutjnl-2018-IDDFabstracts.12

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  117. Significance of Lysyl oxidase-like 2 gene expression on the epithelial-mesenchymal status of hepatocellular carcinoma

    Ninomiya Go, Yamada Suguru, Hayashi Masamichi, Takeda Shigeomi, Suenaga Masaya, Takami Hideki, Kanda Mitsuro, Iwata Naoki, Niwa Yukiko, Tanaka Chie, Kobayashi Daisuke, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    ONCOLOGY REPORTS   Vol. 39 ( 6 ) page: 2664 - 2672   2018.6

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    DOI: 10.3892/or.2018.6349

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  118. Postoperative adalimumab maintenance therapy for Japanese patients with Crohn's disease: a single-center, single-arm phase II trial (CCOG-1107 study)

    Asada Takahiro, Nakayama Goro, Tanaka Chie, Kobayashi Daisuke, Ezaka Kazuhiro, Hattori Norifumi, Kanda Mitsuro, Yamada Suguru, Koike Masahiko, Kodera Yasuhiro

    SURGERY TODAY   Vol. 48 ( 6 ) page: 609 - 617   2018.6

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    DOI: 10.1007/s00595-018-1634-y

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  119. Integrated multigene expression panel to prognosticate patients with gastric cancer.

    Kanda M, Murotani K, Tanaka H, Miwa T, Umeda S, Tanaka C, Kobayashi D, Hayashi M, Hattori N, Suenaga M, Yamada S, Nakayama G, Fujiwara M, Kodera Y

    Oncotarget   Vol. 9 ( 27 ) page: 18775-18785   2018.4

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    DOI: 10.18632/oncotarget.24661

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  120. Clinical implication of nutrition for neoadjuvant therapy and impact of nutritional support in pancreatic cancer.

    Tashiro Mitsuru, Yamada Suguru, Fujii Tsutomu, Hattori Norifumi, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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    DOI: 10.1200/JCO.2018.36.4_suppl.416

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  121. Identification of a novel molecule target for the diagnosis, prediction, and treatment of hepatic metastasis of gastric cancer.

    Kanda Mitsuro, Tanaka Haruyoshi, Miwa Takashi, Kobayashi Daisuke, Tanaka Chie, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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    DOI: 10.1200/JCO.2018.36.4_suppl.53

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  122. Randomized phase II trial of CapOX plus bevacizumab versus CapIRI plus bevacizumab as first-line treatment in Japanese patients with metastatic colorectal cancer (CCOG-1201).

    Sasahara Masahiro, Nakayama Goro, Ishigure Kiyoshi, Yokoyama Hiroyuki, Uehara Keisuke, Ishiyama Akiharu, Matsui Takanori, Nakayama Hiroshi, Kobayashi Daisuke, Umeda Shinichi, Sunagawa Yuki, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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    DOI: 10.1200/JCO.2018.36.4_suppl.781

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  123. Phase II trial of oral S-1 plus bevacizumab for patients with metastatic colorectal cancer refractory to standard chemotherapies (CCOG-1105 study).

    Ezaka Kazuhiro, Nakayama Goro, Yokoyama Hiroyuki, Matsui Takanori, Umeda Shinichi, Sunagawa Yuki, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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    DOI: 10.1200/JCO.2018.36.4_suppl.841

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  124. Phase I study of chemoradiotherapy using gemcitabine plus nab-paclitaxel for unresectable locally advanced pancreatic cancer.

    Yamada Suguru, Fujii Tsutomu, Takano Nao, Takami Hideki, Suenaga Masaya, Niwa Yukiko, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 36 ( 4 ) page: .   2018.2

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    DOI: 10.1200/JCO.2018.36.4_suppl.523

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  125. Effectiveness of plasma activated lactated Ringer's solution on pancreatic cancer cells in vitro and in vivo

    Sato Yusuke, Yamada Suguru, Takeda Shigeomi, Kanda Mitsuo, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    CANCER SCIENCE   Vol. 109   page: 707 - 707   2018.1

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  126. Efficacy and safety of CapeIRI plus bevacizumab therapy as a second-line treatment for patients with metastatic colorectal cancer

    Sunagawa Y., Nakayama G., Hattori N., Ezaka K., Uda H., Umeda S., Sato B., Yamada S., Sugimito H., Koike M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.11

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  127. Evaluation and proposal of novel resectability criteria for pancreatic cancer established by the Japan Pancreas Society

    Yamada Suguru, Fujii Tsutomu, Takami Hideki, Hayashi Masamichi, Iwata Naoki, Kanda Mitsuro, Tanaka Chie, Sugimoto Hiroyuki, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    SURGERY   Vol. 162 ( 4 ) page: 784 - 791   2017.10

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    DOI: 10.1016/j.surg.2017.04.023

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  128. FAM46C Serves as a Predictor of Hepatic Recurrence in Patients with Resectable Gastric Cancer

    Tanaka Haruyoshi, Kanda Mitsuro, Shimizu Dai, Tanaka Chie, Kobayashi Daisuke, Hayashi Masamichi, Iwata Naoki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Niwa Yukiko, Kodera Yasuhiro

    ANNALS OF SURGICAL ONCOLOGY   Vol. 24 ( 11 ) page: 3438 - 3445   2017.10

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    DOI: 10.1245/s10434-016-5636-y

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  129. Involvement of the immunoregulator MZB1 in progression of gastric cancer

    Tanaka Y., Kanda M., Tanaka C., Kobayashi D., Tanaka H., Takami H., Hayashi M., Iwata N., Niwa Y., Yamada S., Nakayama G., Sugimoto H., Koike M., Fujiwara M., Kodera Y.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  130. Primary efficacy results and clinical impact of UGT1A1 genotype on safety from a Phase II study of FOLFOXIRI plus bevacizumab in patients with metastatic colorectal cancer: The QUATTRO study

    Bando H., Kato T., Yoshino T., Muro K., Yamazaki K., Yamaguchi T., Oki E., Iwamoto S., Tsuji A., Nakayama G., Emi Y., Touyama T., Nakamura M., Kotaka M., Kagawa Y., Taniguchi H., Sakisaka H., Yamanaka T., Kanazawa A.

    ANNALS OF ONCOLOGY   Vol. 28   page: .   2017.9

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  131. Usefulness of preoperative estimated glomerular filtration rate to predict complications after curative gastrectomy in patients with clinical T2-4 gastric cancer

    Tanaka Yuri, Kanda Mitsuro, Tanaka Chie, Kobayashi Daisuke, Mizuno Akira, Iwata Naoki, Hayashi Masamichi, Niwa Yukiko, Takami Hideki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Sugimoto Hiroyuki, Fujiwara Michitaka, Kodera Yasuhiro

    GASTRIC CANCER   Vol. 20 ( 4 ) page: 736 - 743   2017.7

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    DOI: 10.1007/s10120-016-0657-6

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  132. Stapling an extracorporeal Billroth-I anastomosis by the complete double stapling technique after laparoscopy-assisted distal gastrectomy

    Tanaka Chie, Fujiwara Michitaka, Kanda Mitsuro, Murotani Kenta, Iwata Naoki, Hayashi Masamichi, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujii Tsutomu, Kodera Yasuhiro

    ASIAN JOURNAL OF ENDOSCOPIC SURGERY   Vol. 10 ( 2 ) page: 137 - 142   2017.5

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    DOI: 10.1111/ases.12357

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  133. The efficacy and safety of CapeOX plus bevacizumab therapy followed by capecitabine plus bevacizumab maintenance therapy in patients with metastatic colorectal cancer: a multi-center, single-arm, phase II study (CCOG-0902)

    Nakayama Goro, Ishigure Kiyoshi, Yokoyama Hiroyuki, Uehara Keisuke, Kojima Hiroshi, Ishiyama Akiharu, Hayashi Naomi, Takano Nao, Hattori Norifumi, Kobayashi Daisuke, Tanaka Chie, Hayashi Masamichi, Kanda Mitsuro, Yamada Suguru, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Murotani Kenta, Ando Yuichi, Kodera Yasuhiro

    BMC CANCER   Vol. 17 ( 1 ) page: 243   2017.4

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    DOI: 10.1186/s12885-017-3245-1

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  134. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma: A retrospective cohort study

    Ninomiya Go, Fujii Tsutomu, Yamada Suguru, Yabusaki Norimitsu, Suzuki Kojiro, Iwata Naoki, Kanda Mitsuro, Hayashi Masamichi, Tanaka Chie, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF SURGERY   Vol. 39   page: 45 - 51   2017.3

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    DOI: 10.1016/j.ijsu.2017.01.075

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  135. The Charlson age comorbidity index predicts prognosis in patients with resected pancreatic cancer

    Asano Tomonari, Yamada Suguru, Fujii Tsutomu, Yabusaki Norimitsu, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF SURGERY   Vol. 39   page: 169 - 175   2017.3

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    DOI: 10.1016/j.ijsu.2017.01.115

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  136. GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis in Patients with Gastric Cancer

    Shimizu Dai, Kanda Mitsuro, Tanaka Haruyoshi, Kobayashi Daisuke, Tanaka Chie, Hayashi Masamichi, Iwata Naoki, Niwa Yukiko, Takami Hideki, Yamada Suguru, Fujii Tsutomu, Nakayama Goro, Fujiwara Michitaka, Kodera Yasuhiro

    SCIENTIFIC REPORTS   Vol. 7   page: 42089   2017.2

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    DOI: 10.1038/srep42089

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  137. The Charlson age comorbidity index to predict prognosis in patients with resected pancreatic cancer.

    Asano Tomonari, Fujii Tsutomu, Yamada Suguru, Yabusaki Norimitsu, Ninomiya Go, Nakayama Goro, Sugimoto Hiroyuki, Koike Masahiko, Fujiwara Michitaka, Kodera Yasuhiro

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 ) page: .   2017.2

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    DOI: 10.1200/JCO.2017.35.4_suppl.495

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  138. Tumor infiltrative pattern predicts sites of recurrence after curative gastrectomy for gastric cancer.

    Kanda, M; Kobayashi, D; Tanaka, C; Yamada, S; Fujii, T; Nakayama, G; Sugimoto, H; Koike, M; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  139. The efficacy and safety of CapeOX plus bevacizumab therapy with a planned oxaliplatin stop-and-go strategy in patients with metastatic colorectal cancer: A multicenter, single-arm, phase II study (CCOG-0902 study).

    Sunakawa, Y; Nakayama, G; Ishigure, K; Yokoyama, H; Uehara, K; Kanda, M; Murotani, K; Fujii, T; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  140. Inverse probability of treatment weighting analysis of upfront surgery versus neoadjuvant chemoradiotherapy followed by surgery for pancreatic adenocarcinoma with arterial abutment.

    Fujii, T; Yamada, S; Murotani, K; Takami, H; Hayashi, M; Kanda, M; Nakayama, G; Sugimoto, H; Koike, M; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  141. Clinical impact of sarcopenia on prognosis in pancreatic ductal adenocarcinoma.

    Ninomiya, G; Fujii, T; Yamada, S; Asano, T; Takano, N; Takami, H; Iwata, N; Kanda, M; Niwa, Y; Hayashi, M; Kobayashi, D; Tanaka, C; Nakayama, G; Sugimoto, H; Fujiwara, M; Koike, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  142. Clinical implication of inflammation-based prognostic score and perioperative nutrition control in pancreatic cancer.

    Takano, N; Yamada, S; Fujii, T; Tashiro, M; Tanaka, N; Morimoto, D; Ninomiya, G; Niwa, Y; Takami, H; Iwata, N; Hayashi, M; Kanda, M; Tanaka, C; Kobayashi, D; Nakayama, G; Sugimoto, H; Koike, M; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  143. Conversion surgery for unresectable gastric cancer following complete response of distant metastasis by systemic chemotherapy.

    Kobayashi, D; Kanda, M; Tanaka, C; Iwata, N; Hayashi, M; Yamada, S; Nakayama, G; Sugimoto, H; Koike, M; Fujii, T; Fujiwara, M; Kodera, Y

    JOURNAL OF CLINICAL ONCOLOGY   Vol. 35 ( 4 )   2017.2

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  144. The protein arginine methyltransferase 5 promotes malignant phenotype of hepatocellular carcinoma cells and is associated with adverse patient outcomes after curative hepatectomy

    Shimizu Dai, Kanda Mitsuro, Sugimoto Hiroyuki, Shibata Masahiro, Tanaka Haruyoshi, Takami Hideki, Iwata Naoki, Hayashi Masamichi, Tanaka Chie, Kobayashi Daisuke, Yamada Suguru, Nakayama Goro, Koike Masahiko, Fujiwara Michitaka, Fujii Tsutomu, Kodera Yasuhiro

    INTERNATIONAL JOURNAL OF ONCOLOGY   Vol. 50 ( 2 ) page: 381 - 386   2017.2

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    DOI: 10.3892/ijo.2017.3833

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  145. PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma

    Kurimoto Keisuke, Hayashi Masamichi, Guerrero-Preston Rafael, Koike Masahiko, Kanda Mitsuro, Hirabayashi Sho, Tanabe Hiroshi, Takano Nao, Iwata Naoki, Niwa Yukiko, Takami Hideki, Kobayashi Daisuke, Tanaka Chie, Yamada Suguru, Nakayama Goro, Sugimoto Hiroyuki, Fujii Tsutomu, Fujiwara Michitaka, Kodera Yasuhiro

    EPIGENETICS   Vol. 12 ( 10 ) page: 865 - 874   2017

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    DOI: 10.1080/15592294.2017.1365207

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. クローン病術後抗TNFα抗体維持療法の有効性と安全性に関する検討

    Grant number:22K08768  2022.4 - 2026.3

    科学研究費助成事業  基盤研究(C)

    中山 吾郎, 山村 健史, 梅田 晋一, 中村 正直, 服部 憲史

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    Authorship:Principal investigator 

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

    クローン病は小腸・大腸を中心とした消化管に慢性肉芽腫性炎症を生じる原因不明の炎症性腸疾患であり,厚生労働省より特定疾患(指定難病)に指定されている.現在クローン病を完治させる治療法はなく,薬物治療により活動性をコントロールし,患者のQoLを高めることが治療の主体である.一方で腸管切除を含む手術が必要となる症例も多く,また術後再発による再手術率が高いことは大きな問題である.本研究では難治性腸管病変に対する手術後の寛解維持療法としての生物学的製剤の再発抑制効果と安全性を臨床第2相試験として検証し,科学的根拠に基づく新たな治療戦略を創世することを目標とする.
    クローン病は小腸・大腸を中心とした消化管に慢性肉芽腫性炎症を生じる原因不明の炎症性腸疾患であり、厚生労働省より特定疾患に指定されている。現在クローン病を完治させる治療法はなく、薬物治療により活動性をコントロールし、患者のQoLを高めることが治療の主体である。一方で腸管切除を含む手術が必要となる症例も多く、また術後再発による再手術率が高いことは大きな問題である。本研究では難治性腸管病変に対する手術後の寛解維持療法としての生物学的製剤の再発抑制効果と安全性を臨床第2相試験として検証し、科学的根拠に基づく新たな治療戦略を創世することを目標とする。
    当施設の炎症性腸疾患治療センターを中心に内科・外科共同でクローン病の難治性腸管病変に対する術後ウステキヌマブ寛解維持療法の有効性と安全性について評価を行った。2022年度は、過去に当院でクローン病に対する腸管切除・吻合術後にウステキヌマブが投与された患者のうち、術前に抗TNF-α抗体薬の投与歴があるクローン病患者(コホートA)16例、術前に抗TNF-α抗体薬の投与歴がないクローン病患者(コホートB)11例を対象として、術後1年の臨床的再発に関して後方視的に検討を行い、本研究の妥当性について検討を行った。各コホートの再発率は、19%/10%と良好であり、この結果をもとに本研究の実施計画書を作成した。2023年度は研究実施計画書を名古屋大学医学部附属病院IRBへ提出し、認可を取得の上で症例登録を開始する(予定登録数50例)。
    2022年度は、本研究の妥当性の検証及び名古屋大学医学部附属病院IRBに提出する研究実施計画書作成を目的とし、historical dataを用いた後方視的検討を行い、本研究の実施計画書を作成した。
    2023年度は研究実施計画書を名古屋大学医学部附属病院IRBへ提出し、認可を取得の上で症例登録を開始する(予定登録数50例)。プロトコール治療(術後、2-4 週の期間にウステキヌマブを開始し、原則内視鏡的もしくは臨床的な再発が確認されるまで継続)及び内視鏡的評価を含むフォローアップは、研究代表者及び研究分担者を中心に実施する。2024年度には、主要評価項目である術後1年内視鏡的吻合部再発率について、2025年度には副次的評価項目(臨床的再発率,再手術率,各無再発生存期間,治療成功期間,有害事象発生割合等)について適宜評価・解析を行い、関連学会や論文において結果を公表する。

  2. Postoperative anti-TNF-alpha monoclonal antibody maintenance therapy for Japanese patients with Crohn's disease

    Grant number:15K10133  2015.4 - 2019.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    NAKAYAMA Goro

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    Authorship:Principal investigator 

    Grant amount:\3900000 ( Direct Cost: \3000000 、 Indirect Cost:\900000 )

    The prevention of postoperative recurrence is a critical issue in surgery for Crohn’s disease (CD). The aim of this study was to investigate the efficacy and safety of planned postoperative anti-TNF-α therapy after surgery in Japanese patients with CD. Twenty-six patients with CD undergoing surgical resection were enrolled. All patients received postoperative anti-TNF-α, adalimumab (ADA), therapy within 2 weeks after surgery. The primary endpoint of this study was the incidence of endoscopic recurrence. Endoscopic recurrence was observed in 31% of patients 1 year after surgery. Univariate analyses show that preoperative ADA therapy was significantly associated with endoscopic recurrence. 17% of patients experienced clinical recurrence 1 year after surgery. Secondary surgery for recurrence was not required. Planned postoperative ADA therapy reduced the incidence of endoscopic and clinical recurrence after bowel resection of Japanese patients with CD.