Faculty Profiles - HONDA, Takashi

Papers - HONDA, Takashi

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Effectiveness of Porous Glass Membrane Pumping Emulsification Device in Transarterial Chemoembolization for Solitary Hepatocellular Carcinoma. Reviewed International journal

Imai N, Ishigami M, Oie Y, Kumagai M, Inukai Y, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Kawashima H

Anticancer research Vol. 42 ( 8 ) page： 3947 - 3951 2022.8

Fecal microbiota transplantation in the treatment of irritable bowel syndrome: a single-center prospective study in Japan. Reviewed International journal

Hamazaki M, Sawada T, Yamamura T, Maeda K, Mizutani Y, Ishikawa E, Furune S, Yamamoto K, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Nakamura M, Fujishiro M

BMC gastroenterology Vol. 22 ( 1 ) page： 342 2022.7

Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma. Reviewed International journal

BMC gastroenterology Vol. 22 ( 1 ) page： 329 2022.7

A case of antiprogrammed death-ligand 1 antibody-induced multisystem immune-related adverse events with pancreatitis and steroid-resistant sclerosing cholangitis. Reviewed International journal

Journal of digestive diseases Vol. 23 ( 7 ) page： 404 - 409 2022.7

Gelsolin as a Potential Biomarker for Endoscopic Activity and Mucosal Healing in Ulcerative Colitis. Reviewed International journal

Maeda Keiko

Biomedicines Vol. 10 ( 4 ) 2022.4

Language：English Publishing type：Research paper (scientific journal)

The therapeutic goal in ulcerative colitis is mucosal healing, which requires improved non-invasive biomarkers to evaluate disease activity. Gelsolin is associated with several autoimmune diseases, and here, we aimed to analyze its usefulness as a serological biomarker for clinical and endoscopic activities in ulcerative colitis. Patients with ulcerative colitis (n = 138) who had undergone blood tests and colonoscopy were included. Serum gelsolin was measured using enzyme-linked immunosorbent assay, and correlation between the gelsolin level and clinical and endoscopic activities was examined. The serum gelsolin level in patients with ulcerative colitis was significantly lower than that in healthy subjects, and it decreased in proportion to increasing Mayo score and Mayo endoscopic subscore. The area under the curve for correlation between clinical and endoscopic remission and serum gelsolin level was higher than that for C-reactive protein. Furthermore, in C-reactive protein-negative patients, the serum gelsolin level was lower in the active phase than in remission. Our findings indicate that the serum gelsolin level correlates with clinical and endoscopic activities in ulcerative colitis, has a higher sensitivity and specificity than C-reactive protein, and can detect mucosal healing, suggesting that gelsolin can be used as a biomarker for ulcerative colitis.

DOI： 10.3390/biomedicines10040872

Scopus

PubMed

CiNii Research

*Differences in the intestinal microbiome associated with diarrhea during lenvatinib treatment for hepatocellular carcinoma Reviewed International journal

Inukai Y, Yamamoto K, Honda T*, Ito T, Imai N, Ishizu Y, Nakamura M, Kawashima H, Ishigami M.

Dig Dis. 2022.3

Changes in Body Composition Predict the Time to Treatment Failure of Lenvatinib in Patients with Advanced Hepatocellular Carcinoma: A Pilot Retrospective Study. Reviewed International journal

Yamamoto T, Imai N, Kuzuya T, Yokoyama S, Yamamoto K, Ito T, Ishizu Y, Honda T, Ishigami M

Nutrition and cancer page： 1 - 10 2022.3

*Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease. Reviewed International journal

Yamamoto K, Ishizu Y, Honda T*, Ito T, Imai N, Nakamura M, Kawashima H, Kitaura Y, Ishigami M, Fujishiro M

Scientific reports Vol. 12 ( 1 ) page： 3674 2022.3

Network Analysis of Gut Microbiota Including Fusobacterium and Oral Origin Bacteria and Their Distribution on Tumor Surface, Normal Mucosa, and in Feces in Patients with Colorectal Cancer. Reviewed International journal

Ohashi A, Yamamura T, Nakamura M, Maeda K, Sawada T, Ishikawa E, Yamamoto K, Ishikawa T, Kakushima N, Furukawa K, Ohno E, Honda T, Kawashima H, Ishigami M, Fujishiro M

Digestion Vol. 103 ( 6 ) page： 451 - 461 2022

Comparison of Endoscopic Ultrasonography and Conventional Endoscopy for Prediction of Tumor Depth in Superficial Nonampullary Duodenal Epithelial Tumors. Reviewed International journal

Matsuda N, Hirose T, Kakushima N, Furukawa K, Furune S, Ishikawa E, Sawada T, Maeda K, Yamamura T, Ishikawa T, Ohno E, Nakamura M, Honda T, Ishigami M, Kawashima H, Fujishiro M

Digestion Vol. 103 ( 4 ) page： 319 - 328 2022

*Changes in the gut microbiota after hepatitis C virus eradication Reviewed International journal

Honda T, Ishigami M, Yamamoto K, Takeyama T, Ito T, Ishizu, Y, Kuzuya T, Nakamura M, Kawashima H, Miyahara R, Tetsuya T, Yoshiki Hirooka Y, Fujishiro M

Scientific Reports 2021.12

*Changes in the gut microbiome in relation to the degree of gastric mucosal atrophy before and after <i>Helicobacter pylori</i> eradication. Reviewed International journal

Furune S, Yamamoto K, Honda T*, Fujiyoshi T, Kakushima N, Furukawa K, Ohno E, Nakamura M, Miyahara R, Kawashima H, Ishigami M, Hirooka Y, Fujishiro M

Scandinavian journal of gastroenterology page： 1 - 8 2021.11

*Microbiome, fibrosis and tumor networks in a non-alcoholic steatohepatitis model of a choline-deficient high-fat diet using diethylnitrosamine. Reviewed International journal

Yamamoto K, Honda T*, Yokoyama S, Ma L, Kato A, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Kawashima H, Ishigami M, Tsuji NM, Fujishiro M

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver Vol. 53 ( 11 ) page： 1443 - 1450 2021.11

*Amino Acid Polymorphism in Hepatitis B Virus Associated With Functional Cure. Reviewed International journal

Honda T, Yamada N, Murayama A, Shiina M, Aly HH, Kato A, Ito T, Ishizu Y, Kuzuya T, Ishigami M, Murakami Y, Tanaka T, Moriishi K, Nishitsuji H, Shimotohno K, Ishikawa T, Fujishiro M, Muramatsu M, Wakita T, Kato T

Cellular and molecular gastroenterology and hepatology Vol. 12 ( 5 ) page： 1583 - 1598 2021.8

*The relationship between oral-origin bacteria in the fecal microbiome and albumin-bilirubin grade in patients with hepatitis C. Reviewed International journal

Yamamoto K, Honda T*, Ito T, Ishizu Y, Kuzuya T, Nakamura M, Miyahara R, Kawashima H, Ishigami M, Fujishiro M

Journal of gastroenterology and hepatology Vol. 36 ( 3 ) page： 790 - 799 2021.3

*Influence of proton pump inhibitors on microbiota in chronic liver disease patients Reviewed International journal

Yamamoto K, Ishigami M, Honda T, Takeyama T, Ito T, Ishizu Y, Kuzuya T, Hayashi K, Goto H, Hirooka Y.

Hepatology International Vol. 13 ( 2 ) page： 234-244 2019.3

*Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice. Reviewed International journal

Honda T, Ishigami M, Luo F, Lingyun M, Ishizu Y, Kuzuya T, Hayashi K, Nakano I, Ishikawa T, Feng GG, Katano Y, Kohama T, Kitaura Y, Shimomura Y, Goto H, Hirooka Y.

Metabolism. Vol. 69 page： 177-187 2017

*The Core I97L mutation in conjunction with P79Q is associated with persistent low HBVDNA and HBs antigen clearance in chronic hepatitis B patients Reviewed International journal

Honda T, Ishigami M, Ishizu Y1, Kuzuya T, Hayashi K, Ishikawa T, Murakami Y, Iwadate M, Umeyama H, Toyoda H, Kumada T, Katano Y, Goto H, Hirooka Y.

Clin Microbiol Infect. Vol. 23 ( 407 ) page： e1-e7 2016.12

*Effect of Peginterferon alfa-2b and Ribavirin on Hepatocellular Carcinoma Prevention in Older Patients with Chronic Hepatitis C Reviewed International journal

Honda T, Ishigami M, Hayashi H, Ishizu Y, Kuzuya T, Hayashi K, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Urano F, Yoshioka K, Toyoda H, Kumada T, Katano Y, Goto H.

J Gastroenterol Hepatol Vol. 30 ( 2 ) page： 321 - 328 2015.2

*Comparison of the efficacy of ribavirin plus peginterferon alfa-2b for chronic hepatitis C infection in patients with and without coagulation disorders Reviewed International journal

Honda T, Katano Y, Kuzuya T, Hayashi K, Ishigami M, Itoh A, Hirooka Y, Nakano I, Ishikawa T, Toyoda H, Kumada T, Yamamoto K, Matsushita T, Kojima T, Takamatsu J, Goto H.

J Med Virol. Vol. 85 ( 2 ) page： 228 - 234 2013.2

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Papers - HONDA, Takashi