Department of Cardiology, Kumamoto University Medical School

1992.4 - 1992.6

National Kumamoto Hospital

1987.4 - 1988.3

Department of Cardiology, Kumamoto University Medical School

1986.10 - 1987.3

Kumamoto Chuou Hospital

1986.4 - 1986.9

Miyazaki Prefectural Nobeoka Hospital

1985.12 - 1986.3

Department of Cardiology, Kumamoto University Medical School

1985.5 - 1985.11

日本動脈硬化学会

European Society of Cardiology   Fellow

2013.1

日本血管生物医学会   理事

2011.4

Early improvement of daily physical activity after catheter ablation for atrial fibrillation in an accelerometer assessment: A prospective pilot study

Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Sakamoto Yusuke, Tomomatsu Toshiro, Mamiya Keita, Okamoto Hiroya, Murohara Toyoaki, Shibata Rei

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 26 ( 1 )   2021.1

No influence on tumor growth by intramuscular injection of adipose-derived regenerative cells: safety evaluation of therapeutic angiogenesis with cell therapy

Suzuki Junya, Shimizu Yuuki, Tsuzuki Kazuhito, Pu Zhongyue, Narita Shingo, Yamaguchi Shukuro, Katagiri Takeshi, Iwata Etsuo, Masutomi Tomohiro, Fujikawa Yusuke, Shibata Rei, Murohara Toyoaki

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY   Vol. 320 ( 1 ) page： H447 - H457   2021.1

Adipolin/C1q/Tnf-related protein 12 prevents adverse cardiac remodeling after myocardial infarction

Takikawa Tomonobu, Ohashi Koji, Ogawa Hayato, Otaka Naoya, Kawanishi Hiroshi, Fang Lixin, Ozaki Yuta, Eguchi Shunsuke, Tatsumi Minako, Takefuji Mikito, Murohara Toyoaki, Ouchi Noriyuki

PLOS ONE   Vol. 15 ( 12 )   2020.12

The prognostic impact of right ventricular dysfunction in patients with septic cardiomyopathy

Hiraiwa H., Kasugai D., Okumura T., Kazama S., Kimura Y., Shibata N., Arao Y., Oishi H., Kato H., Kuwayama T., Yamaguchi S., Kondo T., Furusawa K., Morimoto R., Murohara T.

EUROPEAN HEART JOURNAL   Vol. 41   page： 1836 - 1836   2020.11

Differential Diagnosis of Mechanisms of Exercise-Induced Abnormal Blood Pressure Response in Hypertrophic Cardiomyopathy Without Left Ventricular Outflow Tract Obstruction

Okumura Takahiro, Kano Naoaki, Sawamura Akinori, Kondo Toru, Hiraiwa Hiroaki, Morimoto Ryota, Murohara Toyoaki

CIRCULATION-HEART FAILURE   Vol. 13 ( 10 )   2020.10

Heart Failure and Cancer - A Comorbid Risk That Is No Longer Underestimated -

Kazama Shingo, Bando Yasuko K., Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 10 ) page： 1689 - 1690   2020.10

Impella 5.0 for Cardiogenic Shock After Thrombectomy in a Patient With Intraventricular Thrombosis

Kimura Yuki, Kondo Toru, Mutsuga Masato, Morimoto Ryota, Kazama Shingo, Shibata Naoki, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Kato Hiroo, Yamaguchi Shogo, Hiraiwa Hiroaki, Okumura Takahiro, Fujimoto Kazuro, Usui Akihiko, Murohara Toyoaki

CANADIAN JOURNAL OF CARDIOLOGY   Vol. 36 ( 10 )   2020.10

Therapeutic angiogenesis using autologous adipose-derived regenerative cells in patients with critical limb ischaemia in Japan: a clinical pilot study

Katagiri Takeshi, Kondo Kazuhisa, Shibata Rei, Hayashida Ryo, Shintani Satoshi, Yamaguchi Shukuro, Shimizu Yuuki, Unno Kazumasa, Kikuchi Ryosuke, Kodama Akio, Takanari Keisuke, Kamei Yuzuru, Komori Kimihiro, Murohara Toyoaki

SCIENTIFIC REPORTS   Vol. 10 ( 1 )   2020.9

Efficacy of Pulmonary Artery Pulsatility Index as a Measure of Right Ventricular Dysfunction in Stable Phase of Dilated Cardiomyopathy

Kuwayama Tasuku, Morimoto Ryota, Oishi Hideo, Kato Hiroo, Kimura Yuki, Kazama Shingo, Shibata Naoki, Arao Yoshihito, Yamaguchi Shogo, Hiraiwa Hiroaki, Kondo Toru, Furusawa Kenji, Okumura Takahiro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 9 ) page： 1536 - +   2020.9

Single-center prognostic validation of the risk assessment of the 2015 ESC/ERS guidelines in patients with pulmonary arterial hypertension in Japan

Imai Ryo, Adachi Shiro, Yoshida Masahiro, Shimokata Shigetake, Nakano Yoshihisa, Okumura Naoki, Murohara Toyoaki, Kondo Takahisa

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY   Vol. 98 ( 9 ) page： 653 - 658   2020.9

C1q/TNF-Related Protein 9 Promotes Revascularization in Response to Ischemiaviaan eNOS-Dependent Manner

Yamaguchi Shukuro, Shibata Rei, Ohashi Koji, Enomoto Takashi, Ogawa Hayato, Otaka Naoya, Hiramatsu-Ito Mizuho, Masutomi Tomohiro, Kawanishi Hiroshi, Murohara Toyoaki, Ouchi Noriyuki

FRONTIERS IN PHARMACOLOGY   Vol. 11   2020.8

Role of Cryptochrome in Angiogenesis

Tsuzuki Kazuhito, Shimizu Yuuki, Pu Zhongyue, Suzuki Jyunya, Murohara Toyoaki

CIRCULATION RESEARCH   Vol. 127   2020.7

Usefulness of Plasma Branched-Chain Amino Acid Analysis in Predicting Outcomes of Patients with Nonischemic Dilated Cardiomyopathy

Kimura Yuki, Okumura Takahiro, Kazama Shingo, Shibata Naoki, Oishi Hideo, Arao Yoshihito, Kuwayama Tasuku, Kato Hiroo, Yamaguchi Shogo, Hiraiwa Hiroaki, Kondo Toru, Morimoto Ryota, Murohara Toyoaki

INTERNATIONAL HEART JOURNAL   Vol. 61 ( 4 ) page： 739 - 747   2020.7

A novel selective PPAR alpha modulator, pemafibrate promotes ischemia-induced revascularization through the eNOS-dependent mechanisms

Kawanishi Hiroshi, Ohashi Koji, Ogawa Hayato, Otaka Naoya, Takikawa Tomonobu, Fang Lixin, Ozaki Yuta, Takefuji Mikito, Murohara Toyoaki, Ouchi Noriyuki

PLOS ONE   Vol. 15 ( 6 )   2020.6

Can Pharmacological Ischemic Preconditioning Affect Myocardial Ischemic Injury?

Ohashi Koji, Ouchi Noriyuki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 6 ) page： 891 - 893   2020.6

Prediction of Thromboembolism in Patients With Hypertrophic Cardiomyopathy

Okumura Takahiro, Kimura Yuki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 5 ) page： 700 - 701   2020.5

Lipid-rich large plaques in a non-culprit left main coronary artery and long-term clinical outcomes

Tashiro Hiroshi, Tanaka Akihito, Ishii Hideki, Sakakibara Keisuke, Tobe Akihiro, Kataoka Takashi, Miki Yusuke, Hitora Yusuke, Niwa Kiyoshi, Furusawa Kenji, Murohara Toyoaki

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 305   page： 5 - 10   2020.4

Therapeutic Angiogenesis Using Bone Marrow Mononuclear Cell Transplantation - A New Standard Treatment for Thromboangiitis Obliterans?

Shibata Rei, Yamaguchi Shukuro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 4 ) page： 549 - 550   2020.4

Electrocardiogram characteristics of P wave associated with successful pulmonary vein isolation in patients with paroxysmal atrial fibrillation: Significance of changes in P-wave duration and notched P wave

Yanagisawa Satoshi, Inden Yasuya, Okamoto Hiroya, Fujii Aya, Sakamoto Yusuke, Mamiya Keita, Tomomatsu Toshiro, Shibata Rei, Murohara Toyoaki

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 25 ( 2 )   2020.3

The role of lymphangiogenesis in ischemia-induced angiogenesis for peripheral artery disease

Pu Zhongyue, Shimizu Yuuki, Murohara Toyoaki

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY   Vol. 140   page： 16 - 17   2020.3

Anatomical assessment of crosstalk phenomenon during laser balloon ablation with imaging in a patient with unusual atrial hypertrophy

Yanagisawa Satoshi, Inden Yasuya, Okamoto Hiroya, Tomomatsu Toshiro, Fujii Aya, Mamiya Keita, Shibata Rei, Murohara Toyoaki

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 57 ( 1 ) page： 157 - 159   2020.1

Advantages and Emerging Problems of Novel Treatments for Transthyretin Cardiac Amyloidosis

Okumura Takahiro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 84 ( 1 ) page： 9 - 10   2020.1

Therapeutic Angiogenesis with Somatic Stem Cell Transplantation

Murohara Toyoaki

KOREAN CIRCULATION JOURNAL   Vol. 50 ( 1 ) page： 12 - 21   2020.1

Impact of Diabetes Mellitus on the Aortic Wall Changes as Atherosclerosis Progresses: Aortic Dilatation and Calcification

Iwakawa Naoki, Tanaka Akihito, Ishii Hideki, Kataoka Takashi, Niwa Kiyoshi, Hitora Yusuke, Tashiro Hiroshi, Mitsuda Takayuki, Kojima Hiroki, Hirayama Kenshi, Furusawa Kenji, Yoshida Ruka, Suzuki Susumu, Murohara Toyoaki

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   Vol. 27 ( 6 ) page： 509 - 515   2020

Prognostic impact of mitral L-wave in patients with hypertrophic cardiomyopathy without risk factors for sudden cardiac death

Sugiura Yuki, Morimoto Ryota, Aoki Soichiro, Yamaguchi Shogo, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Okumura Takahiro, Murohara Toyoaki

HEART AND VESSELS   Vol. 34 ( 12 ) page： 2002 - 2010   2019.12

Prothrombotic Responses After Catheter Ablation for Atrial Fibrillation During Uninterrupted Oral Anticoagulant Agent Administration

Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Sakamoto Yusuke, Tomomatsu Toshiro, Mamiya Keita, Okamoto Hiroya, Shibata Rei, Murohara Toyoaki

JACC-CLINICAL ELECTROPHYSIOLOGY   Vol. 5 ( 12 ) page： 1418 - 1427   2019.12

Heart rate control using beta-blockers for heart failure with atrial fibrillation: more than enough is too much

Okumura Takahiro, Kimura Yuki, Murohara Toyoaki

HYPERTENSION RESEARCH   Vol. 42 ( 11 ) page： 1826 - 1827   2019.11

How Do We Improve the Utility of Fractional Flow Reserve? - For Precise Diagnosis of Myocardial Ischemia -

Ishii Hideki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 83 ( 10 ) page： 1986 - 1987   2019.10

Effects of Tobacco Smoking on Cardiovascular Disease

Kondo Takahisa, Nakano Yoshihisa, Adachi Shiro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 83 ( 10 ) page： 1980 - 1985   2019.10

Early blood pressure reduction by intravenous vasodilators associates with acute kidney injury in patients with hypertensive acute decompensated heart failure

Arao Y., Sawamura A., Nakatochi M., Oishi H., Kato H., Yamaguchi S., Haga T., Kuwayama T., Yokoi T., Hiraiwa H., Kondo T., Morimoto R., Okumura T., Murohara T.

EUROPEAN HEART JOURNAL   Vol. 40   page： 884 - 884   2019.10

Unsolved Issue in Left Ventricular Noncompaction: Is the Strange Form of Myocardium Congenital or Acquired?

Okumura Takahiro, Murohara Toyoaki

CARDIOLOGY   Vol. 143 ( 3-4 ) page： 105 - 106   2019.10

Kidney Measures to Improve Risk Discrimination of Cardiovascular Events

Ishii Hideki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 83 ( 9 ) page： 1836 - 1837   2019.9

T-wave changes of cardiac memory caused by frequent premature ventricular contractions originating from the right ventricular outflow tract

Sakamoto Yusuke, Inden Yasuya, Okamoto Hiroya, Mamiya Keita, Tomomatsu Toshiro, Fujii Aya, Yanagisawa Satoshi, Shibata Rei, Hirai Makoto, Murohara Toyoaki

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 30 ( 9 ) page： 1549 - 1556   2019.9

Adipolin/C1q/Tnf-related Protein 12 reduces Neointimal Formation And Atherosclerotic Lesion Development By Modulation Of Macrophage Inflammatory Response And Endothelial Cell Function

Ohashi Koji, Ogawa Hayato, Enomoto Takashi, Otaka Naoya, Murohara Toyoaki, Ouchi Noriyuki

CIRCULATION RESEARCH   Vol. 125   2019.8

Cardiomyocytes capture stem cell-derived, anti-apoptotic microRNA-214 via clathrin-mediated endocytosis in acute myocardial infarction

Eguchi Shunsuke, Takefuji Mikito, Sakaguchi Teruhiro, Ishihama Sohta, Mori Yu, Tsuda Takuma, Takikawa Tomonobu, Yoshida Tatsuya, Ohashi Koji, Shimizu Yuuki, Hayashida Ryo, Kondo Kazuhisa, Bando Yasuko K., Ouchi Noriyuki, Murohara Toyoaki

JOURNAL OF BIOLOGICAL CHEMISTRY   Vol. 294 ( 31 ) page： 11665 - 11674   2019.8

Impaired Autophagic Off-rate Causes Cardiac Aging in Progeria Mouse Model

Bando Yasuko K., Kamihara Takahiro, Murohara Toyoaki

CIRCULATION RESEARCH   Vol. 125   2019.8

Identification of precise accessory pathway using ultra-high-resolution three-dimensional mapping system: utility and feasibility in preliminary experience

Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Sakamoto Yusuke, Ichiyanagi Hiroshi, Shibata Rei, Murohara Toyoaki

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 55 ( 2 ) page： 241 - 242   2019.8

His bundle pacing with unusual automaticity

Yanagisawa Satoshi, Inden Yasuya, Shibata Rei, Murohara Toyoaki

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 30 ( 6 ) page： 966 - 968   2019.6

Renin Activity as a Key Predictor of Major Adverse Cardiac Events

Kondo Takahisa, Nakano Yoshihisa, Adachi Shiro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 83 ( 6 ) page： 1204 - 1205   2019.6

Adjacentmultiple accessory pathways demonstrated on ultra-high-resolution mapping

Yanagisawa Satoshi, Inden Yasuya, Murohara Toyoaki

EUROPACE   Vol. 21 ( 5 ) page： 723 - 723   2019.5

Circulation Journal Awards for the Year 2018

Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 83 ( 3 ) page： 495 - 503   2019.3

Myocardial viability as shown by left ventricular lead pacing threshold and improved dyssynchrony by QRS narrowing predicts the response to cardiac resynchronization therapy

Takenaka Masaki, Inden Yasuya, Yanagisawa Satoshi, Fujii Aya, Ando Monami, Funabiki Junya, Murase Yosuke, Otake Noriaki, Sakamoto Yusuke, Shibata Rei, Murohara Toyoaki

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY   Vol. 30 ( 3 ) page： 311 - 319   2019.3

Contrast-Induced Nephropathy and Long-Term Clinical Outcomes Following Percutaneous Coronary Intervention in Patients With Advanced Renal Dysfunction (Estimated Glomerular Filtration Rate <30 ml/min/1.73 m²).

Negishi Y, Tanaka A, Ishii H, Takagi K, Inoue Y, Uemura Y, Umemoto N, Yoshioka N, Morishima I, Asano H, Watarai M, Shibata N, Suzuki S, Murohara T

The American journal of cardiology   Vol. 123 ( 3 ) page： 361-367   2019.2

Prognostic value of left ventricular dyssynchrony evaluated by gated myocardial perfusion imaging in patients with chronic kidney disease and normal perfusion defect scores.

Mori H, Isobe S, Suzuki S, Unno K, Morimoto R, Kano N, Okumura T, Yasuda Y, Kato K, Murohara T

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology   Vol. 26 ( 1 ) page： 288 - 297   2019.2

Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.

Takefuji M, Murohara T

Circulation journal : official journal of the Japanese Circulation Society   Vol. 83 ( 2 ) page： 261 - 266   2019.2

Editorial Statistics and Best Reviewers Award for 2018.

Murohara T

Circulation journal : official journal of the Japanese Circulation Society   Vol. 83 ( 2 ) page： 249 - 251   2019.2

Differential effect of concomitant antidiabetic agents on carotid atherosclerosis: a subgroup analysis of the PROLOGUE study.

Tanaka A, Kawaguchi A, Oyama JI, Ishizu T, Ito H, Fukui J, Kondo T, Kuroki S, Nanasato M, Higashi Y, Kaku K, Inoue T, Murohara T, Node K

Heart and vessels   Vol. 34 ( 2 ) page： 375-384   2019.2

Pulmonary Hypertension: Diagnosis, Management, and Treatment

Kondo Takahisa, Okumura Naoki, Adachi Shiro, Murohara Toyoaki

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 81 ( 1 ) page： 19 - 30   2019.2

Impact of adjunctive use of guide extension catheter for mid-term outcome of drug-coated balloon.

Yoshida R, Ishii H, Morishima I, Tanaka A, Takagi K, Iwakawa N, Tashiro H, Kojima H, Mitsuda T, Hirayama K, Hitora Y, Furusawa K, Murohara T

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     2019.1

Hemodynamics of cardiac tamponade during extracorporeal membrane oxygenation support in a patient with fulminant myocarditis.

Kondo T, Morimoto R, Yokoi T, Yamaguchi S, Kuwayama T, Haga T, Hiraiwa H, Sugiura Y, Watanabe N, Kano N, Ichii T, Fukaya K, Sawamura A, Okumura T, Yoshizumi T, Mutsuga M, Fujimoto K, Matsuda N, Usui A, Murohara T

Journal of cardiology cases   Vol. 19 ( 1 ) page： 22-24   2019.1

Anti-angiogenic isoform of vascular endothelial growth factor-A in cardiovascular and renal disease.

Kikuchi R, Stevens M, Harada K, Oltean S, Murohara T

Advances in clinical chemistry   Vol. 88   page： 1-33   2019

Performance of HAS-BLED, ORBIT, PRECISE-DAPT, and PARIS risk score for predicting long-term bleeding events in patients taking an oral anticoagulant undergoing percutaneous coronary intervention.

Yoshida R, Ishii H, Morishima I, Tanaka A, Morita Y, Takagi K, Yoshioka N, Hirayama K, Iwakawa N, Tashiro H, Kojima H, Mitsuda T, Hitora Y, Furusawa K, Tsuboi H, Murohara T

Journal of cardiology     2018.12

Impact of Nutritional and Inflammation Status on Long-Term Bleeding in Patients Undergoing Percutaneous Coronary Intervention with an Oral Anticoagulant.

Yoshida R, Ishii H, Morishima I, Tanaka A, Morita Y, Takagi K, Yoshioka N, Hirayama K, Iwakawa N, Tashiro H, Kojima H, Mitsuda T, Hitora Y, Furusawa K, Tsuboi H, Murohara T

Journal of atherosclerosis and thrombosis     2018.12

Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial.

J-DAVID Investigators., Shoji T, Inaba M, Fukagawa M, Ando R, Emoto M, Fujii H, Fujimori A, Fukui M, Hase H, Hashimoto T, Hirakata H, Honda H, Hosoya T, Ikari Y, Inaguma D, Inoue T, Isaka Y, Iseki K, Ishimura E, Itami N, Ito C, Kakuta T, Kawai T, Kawanishi H, Kobayashi S, Kumagai J, Maekawa K, Masakane I, Minakuchi J, Mitsuiki K, Mizuguchi T, Morimoto S, Murohara T, Nakatani T, Negi S, Nishi S, Nishikawa M, Ogawa T, Ohta K, Ohtake T, Okamura M, Okuno S, Shigematsu T, Sugimoto T, Suzuki M, Tahara H, Takemoto Y, Tanaka K, Tominaga Y, Tsubakihara Y, Tsujimoto Y, Tsuruya K, Ueda S, Watanabe Y, Yamagata K, Yamakawa T, Yano S, Yokoyama K, Yorioka N, Yoshiyama M, Nishizawa Y

JAMA   Vol. 320 ( 22 ) page： 2325-2334   2018.12

Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury

Otaka Naoya, Shibata Rei, Ohashi Koji, Uemura Yusuke, Kambara Takahiro, Enomoto Takashi, Ogawa Hayato, Ito Masanori, Kawanishi Hiroshi, Maruyama Sonomi, Joki Yusuke, Fujikawa Yusuke, Narita Shingo, Unno Kazumasa, Kawamoto Yoshiyuki, Murate Takashi, Murohara Toyoaki, Ouchi Noriyuki

CIRCULATION RESEARCH   Vol. 123 ( 12 ) page： 1326-1338   2018.12

A Novel Selective PPAR[alpha] Modulator, Pemafibrate Promotes Ischemia-Induced Revascularization

Kawanishi Hiroshi, Ohashi Koji, Shibata Rei, Murohara Toyoaki, Ouchi Noriyuki

CIRCULATION   Vol. 138   2018.11

Maintenance of Undifferentiated Mesenchymal Stromal Cells-Like Fibroblast by Meflin is Crucial for Heart Repair and Homeostasis

Hara Akitoshi, Enomoto Atsushi, Murohara Toyoaki

CIRCULATION   Vol. 138   2018.11

Physiological Glucagon Acts as a Guardian of the Heart Against Catecholamine Surge Induced by Pressure-Overload

Nishimura Kazuyuki, Bando Yasuko K., Kamihara Takahiro, Ozaki Reina, Yasheng Remina, Murohara Toyoaki

CIRCULATION   Vol. 138   2018.11

Achieving LDL cholesterol target levels <1.81 mmol/L may provide extra cardiovascular protection in patients at high risk: Exploratory analysis of the Standard Versus Intensive Statin Therapy for Patients with Hypercholesterolaemia and Diabetic Retinopathy study.

Itoh H, Komuro I, Takeuchi M, Akasaka T, Daida H, Egashira Y, Fujita H, Higaki J, Hirata KI, Ishibashi S, Isshiki T, Ito S, Kashiwagi A, Kato S, Kitagawa K, Kitakaze M, Kitazono T, Kurabayashi M, Miyauchi K, Murakami T, Murohara T, Node K, Ogawa S, Saito Y, Seino Y, Shigeeda T, Shindo S, Sugawara M, Sugiyama S, Terauchi Y, Tsutsui H, Ueshima K, Utsunomiya K, Yamagishi M, Yamazaki T, Yo S, Yokote K, Yoshida K, Yoshimura M, Yoshimura N, Nakao K, Nagai R, EMPATHY Investigators.

Diabetes, obesity & metabolism     2018.11

Clinical significance of the timing of early recurrence of atrial arrhythmia after pulmonary vein isolation: a two-institution clinical study.

Murase Y, Inden Y, Imai H, Kyo S, Yanagisawa S, Fujii A, Sakamoto Y, Tomomatsu T, Murohara T

Heart and vessels     2018.11

Palliative and end-of-life care for heart failure patients in an aging society

Okumura Takahiro, Sawamura Akinori, Murohara Toyoaki

KOREAN JOURNAL OF INTERNAL MEDICINE   Vol. 33 ( 6 ) page： 1039 - 1049   2018.11

Prognostic Impact of the Preservation of Activities of Daily Living on Post-Discharge Outcomes in Patients With Acute Heart Failure

Uemura Yusuke, Shibata Rei, Takemoto Kenji, Koyasu Masayoshi, Ishikawa Shinji, Murohara Toyoaki, Watarai Masato

CIRCULATION JOURNAL   Vol. 82 ( 11 ) page： 2793-+   2018.11

Impact of periprocedural anticoagulation therapy on the incidence of silent stroke after atrial fibrillation ablation in patients receiving direct oral anticoagulants: uninterrupted vs. interrupted by one dose strategy.

Nagao T, Suzuki H, Matsunaga S, Nishikawa Y, Harada K, Mamiya K, Shinoda N, Harada K, Kato M, Marui N, Amano T, Inden Y, Murohara T

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     2018.10

Impact of Lymphangiogenesis on Cardiac Remodeling After Ischemia and Reperfusion Injury

Shimizu Yuuki, Polavarapu Rohini, Eskla Kattri-Liis, Pantner Yvanna, Nicholson Chad K., Ishii Masakazu, Brunnhoelzl Daniel, Mauria Rohit, Husain Ahsan, Naqvi Nawazish, Murohara Toyoaki, Calvert John W.

JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 7 ( 19 ) page： e009565   2018.10

Left ventricular phase entropy: Novel prognostic predictor in patients with dilated cardiomyopathy and narrow QRS.

Kano N, Okumura T, Isobe S, Sawamura A, Watanabe N, Fukaya K, Mori H, Morimoto R, Kato K, Bando YK, Murohara T

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology   Vol. 25 ( 5 ) page： 1677 - 1687   2018.10

ALTERED CARDIAC AUTONOMIC ACTIVITY, ARRHYTHMIAS, AND CARDIAC DEATH IN A RAT MODEL OF METABOLIC SYNDROME

Nagata Kohzo, Nakano Shiho, Minamiya Moeko, Azuma Naoki, Mizumoto Hisashi, Yoneda Mamoru, Komatsu Yuki, Aoyama Kiyoshi, Ashikawa Nao, Murohara Toyoaki, Uchinaka Ayako

JOURNAL OF HYPERTENSION   Vol. 36   page： E71-E71   2018.10

Usefulness of scoring right ventricular function for assessment of prognostic factors in patients with chronic thromboembolic pulmonary hypertension

Kamimura Yoshihiro, Okumura Naoki, Adachi Shiro, Shimokata Shigetake, Tajima Fumitaka, Nakano Yoshihisa, Hirashiki Akihiro, Murohara Toyoaki, Kondo Takahisa

HEART AND VESSELS   Vol. 33 ( 10 ) page： 1220-1228   2018.10

Trade-Off Between Lipid-Lowering Therapy and Costs in Patients With Cardiovascular Disease

Ishii Hideki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 82 ( 10 ) page： 2481 - 2482   2018.10

Adiponectin/AdiopR1 signal inactivation contributes to impaired angiogenesis in mice of advanced age

Piao Limei, Yu Chenglin, Xu Wenhu, Inoue Aiko, Shibata Rei, Li Xiang, Nan Yongshan, Zhao Guangxian, Wang Hailong, Meng Xiangkun, Lei Yanna, Goto Hiroki, Ouchi Noriyuki, Murohara Toyoaki, Kuzuya Masafumi, Cheng Xian Wu

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 267   page： 150-155   2018.9

Influence of chronic kidney disease and worsening renal function on clinical outcomes in patients undergoing primary percutaneous coronary intervention.

Aoki T, Ishii H, Tanaka A, Suzuki S, Ichimiya S, Kanashiro M, Murohara T

Clinical and experimental nephrology     2018.9

Comparison of two dosing methods for immediate administration of tolvaptan in acute decompensated heart failure.

Oguri M, Ishii H, Ohguchi S, Takahara K, Kawamura Y, Yokoi Y, Izumi K, Takahashi H, Kamiya H, Murohara T

Journal of cardiology   Vol. 72 ( 3 ) page： 234-239   2018.9

Randomized Trial of Effect of Urate-Lowering Agent Febuxostat in Chronic Heart Failure Patients with Hyperuricemia (LEAF-CHF ) Study Design

Yokota Takashi, Fukushima Arata, Kinugawa Shintaro, Okumura Takahiro, Murohara Toyoaki, Tsutsui Hiroyuki

INTERNATIONAL HEART JOURNAL   Vol. 59 ( 5 ) page： 976-982   2018.9

Long-term clinical outcomes after coronary artery bypass graft versus everolimus-eluting stent implantation in chronic hemodialysis patients

Kumada Yoshitaka, Ishii Hideki, Aoyama Toru, Kamoi Daisuke, Sakakibara Takashi, Umemoto Norio, Ito Ryuta, Takahashi Hiroshi, Murohara Toyoaki

CORONARY ARTERY DISEASE   Vol. 29 ( 6 ) page： 489-494   2018.9

A multicenter prospective cohort study to develop frailty-based prognostic criteria in heart failure patients (FLAGSHIP): rationale and design

Yamada Sumio, Adachi Takuji, Izawa Hideo, Murohara Toyoaki, Kondo Takaaki

BMC CARDIOVASCULAR DISORDERS   Vol. 18 ( 1 ) page： 159   2018.8

Comparison Between Long-Term Clinical Outcomes of Vitamin K Antagonist and Direct Oral Anticoagulants in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

Yoshida Ruka, Morishima Itsuro, Takagi Kensuke, Morita Yasuhiro, Tsuboi Hideyuki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 82 ( 8 ) page： 2016-+   2018.8

Promising method for management of venoarterial extracorporeal membrane oxygenation: A case of severe heart failure successfully stabilized by "high-flow/vasodilation method".

Kondo T, Sawamura A, Okumura T, Kano N, Morimoto R, Watanabe N, Hiraiwa H, Kuwayama T, Sugiura Y, Haga T, Yamaguchi S, Fukaya K, Yokoi T, Fujimoto K, Mutsuga M, Yoshizumi T, Matsuda N, Usui A, Murohara T

Journal of cardiology cases   Vol. 18 ( 2 ) page： 81-84   2018.8

Prognostic Value of Electrocardiography in Patients With Fulminant Myocarditis Supported by Percutaneous Venoarterial Extracorporeal Membrane Oxygenation　- Analysis From the CHANGE PUMP Study.

  Vol. 82 ( 8 ) page： 2089-2095   2018.7

High-Normal Thyroid-Stimulating Hormone Shows a Potential Causal Association With Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation

Morishima Itsuro, Okumura Kenji, Morita Yasuhiro, Kanzaki Yasunori, Takagi Kensuke, Yoshida Ruka, Nagai Hiroaki, Ikai Yoshihiro, Furui Koichi, Yoshioka Naoki, Tsuboi Hideyuki, Murohara Toyoaki

JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 7 ( 14 )   2018.7

Are Sodium-Glucose Cotransporter 2 Inhibitors Really Useful and Safe for Advanced Heart Failure?

Okumura Takahiro, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 82 ( 7 ) page： 1752 - 1753   2018.7

Clinical Impact of Circulating Irisin on Classified Coronary Plaque Characteristics

Hirayama Kenshi, Ishii Hideki, Kikuchi Ryosuke, Suzuki Susumu, Aoki Toshijiro, Harada Kazuhiro, Sumi Takuya, Negishi Yosuke, Shibata Yohei, Tatami Yosuke, Tanaka Akihito, Murohara Toyoaki

JOURNAL OF APPLIED LABORATORY MEDICINE   Vol. 3 ( 1 ) page： 79 - 88   2018.7

ADIPOLIN/C1Q/TNF-RELATED PROTEIN 12 ACTS AS A BIOMARKER OF CORONARY ARTERY DISEASE AND PREVENTS THE PATHOLOGICAL VASCULAR REMODELING

Ogawa Hayato, Ohashi Koji, Murohara Toyoaki, Ouchi Noriyuki

ATHEROSCLEROSIS SUPPLEMENTS   Vol. 32   page： 10-11   2018.6

Nonsustained ventricular tachycardia does not affect the prognosis of neuromuscular diseases: A preliminary and retrospective study

Kamihara Takahiro, Yasuma Fumihiko, Murohara Toyoaki

JOURNAL OF ARRHYTHMIA   Vol. 34 ( 3 ) page： 254-260   2018.6

Late-Onset Fulminant Myocarditis With Immune Checkpoint Inhibitor Nivolumab

Yamaguchi Shogo, Morimoto Ryota, Okumura Takahiro, Yamashita Yuta, Haga Tomoaki, Kuwayama Tasuku, Yokoi Tsuyoshi, Hiraiwa Hiroaki, Kondo Toru, Sugiura Yuki, Watanabe Naoki, Kano Naoaki, Kohno Kei, Fukaya Kenji, Sawamura Akinori, Yokota Kenji, Ishii Hideki, Nakaguro Masato, Akiyama Masashi, Murohara Toyoaki

CANADIAN JOURNAL OF CARDIOLOGY   Vol. 34 ( 6 ) page： 812.e1-812.e3   2018.6

Intensive Treat-to-Target Statin Therapy in High-Risk Japanese Patients With Hypercholesterolemia and Diabetic Retinopathy: Report of a Randomized Study.

Itoh H, Komuro I, Takeuchi M, Akasaka T, Daida H, Egashira Y, Fujita H, Higaki J, Hirata KI, Ishibashi S, Isshiki T, Ito S, Kashiwagi A, Kato S, Kitagawa K, Kitakaze M, Kitazono T, Kurabayashi M, Miyauchi K, Murakami T, Murohara T, Node K, Ogawa S, Saito Y, Seino Y, Shigeeda T, Shindo S, Sugawara M, Sugiyama S, Terauchi Y, Tsutsui H, Ueshima K, Utsunomiya K, Yamagishi M, Yamazaki T, Yo S, Yokote K, Yoshida K, Yoshimura M, Yoshimura N, Nakao K, Nagai R, EMPATHY Investigators.

Diabetes care   Vol. 41 ( 6 ) page： 1275-1284   2018.6

Effects of ramelteon on cardiac injury and adipose tissue pathology in rats with metabolic syndrome

Uchinaka Ayako, Kawashima Yuri, Sano Yuki, Ito Shogo, Sano Yusuke, Nagasawa Kai, Matsuura Natsumi, Yoneda Mamoru, Yamada Yuichiro, Murohara Toyoaki, Nagata Kohzo

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES   Vol. 1421 ( 1 ) page： 73 - 87   2018.6

Association between the ratio of anti-angiogenic isoform of VEGF-A to total VEGF-A and adverse clinical outcomes in patients after acute myocardial infarction

Harada Kazuhiro, Kikuchi Ryosuke, Ishii Hideki, Shibata Yohei, Suzuki Susumu, Tanaka Akihito, Suzuki Atsuo, Hirayama Kenshi, Murohara Toyoaki

IJC HEART & VASCULATURE   Vol. 19   page： 3-7   2018.6

Anti-inflammatory effects of heat-killed Lactobacillus plantarum L-137 on cardiac and adipose tissue in rats with metabolic syndrome

Uchinaka Ayako, Azuma Naoki, Mizumoto Hisashi, Nakano Shiho, Minamiya Moeko, Yoneda Mamoru, Aoyama Kiyoshi, Komatsu Yuki, Yamada Yuichiro, Murohara Toyoaki, Nagata Kohzo

SCIENTIFIC REPORTS   Vol. 8 ( 1 ) page： 8156   2018.5

Left ventricular end-diastolic dimension and septal e' are predictors of cardiac index at rest, while tricuspid annular plane systolic excursion is a predictor of peak oxygen uptake in patients with pulmonary hypertension.

Nakano Y, Okumura N, Adachi S, Shimokata S, Tajima F, Kamimura Y, Murohara T, Kondo T

Heart and vessels   Vol. 33 ( 5 ) page： 521 - 528   2018.5

Left ventricular hypertrophy and proteinuria in patients with essential hypertension in Andkhoy, Afghanistan.

Shoaib Hamrah M, Hassan Hamrah M, Ishii H, Suzuki S, Hussain Hamrah M, Edris Hamrah A, Elias Dahi A, Yisireyili M, Kano N, Takeshita K, Hashem Hamrah M, Sakamoto J, Murohara T

Nagoya journal of medical science   Vol. 80 ( 2 ) page： 249-255   2018.5

Uninterrupted Direct Oral Anticoagulant and Warfarin Administration in Elderly Patients Undergoing Catheter Ablation for Atrial Fibrillation: A Comparison With Younger Patients.

Yanagisawa S, Inden Y, Fujii A, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

JACC. Clinical electrophysiology   Vol. 4 ( 5 ) page： 592 - 600   2018.5

Announcement of the 2018 JCS Meeting Activities (2).

Murohara T

Circulation journal : official journal of the Japanese Circulation Society   Vol. 82 ( 5 ) page： 1219-1221   2018.4

Association between Helicobacter pylori Infection and Cardiovascular Risk Factors among Patients in the Northern Part of Afghanistan: a Cross-Sectional Study in Andkhoy City

Hamrah MS, Hamrah MH, Ishii H, Suzuki S, Hamrah MH, Hamrah AE, Dahi AE, Takeshita K, Hamrah MH, Fotouhi A, Sakamoto J, Murohara T

Asian Pacific journal of cancer prevention : APJCP   Vol. 19 ( 4 ) page： 1035-1039   2018.4

Ultrasonographic and radiological imaging demonstrating an anomalous origin of the left coronary artery causing acute coronary syndrome in an adolescent.

Taniguchi T, Umemoto N, Ishii H, Nakahata K, Shibata N, Mizutani T, Yamada M, Shimizu K, Murohara T

Journal of cardiology cases   Vol. 17 ( 4 ) page： 141-145   2018.4

Rapid Publication and Announcement of the 2018 JCS Meeting Activities.

Murohara T

Circulation journal : official journal of the Japanese Circulation Society   Vol. 82 ( 4 ) page： 935-936   2018.3

Skeletal Muscle Pump Function Is Associated With Exercise Capacity in Patients With Heart Failure.

Kondo T, Yamada S, Asai C, Okumura T, Tanimura D, Murohara T

Circulation journal : official journal of the Japanese Circulation Society     2018.3

Balance between angiogenic and anti-angiogenic isoforms of VEGF-A is associated with the complexity and severity of coronary artery disease

Shibata Yohei, Kikuchi Ryosuke, Ishii Hideki, Suzuki Susumu, Harada Kazuhiro, Hirayama Kenshi, Suzuki Atsuo, Tatami Yosuke, Kondo Kazuhisa, Murohara Toyoaki

CLINICA CHIMICA ACTA   Vol. 478   page： 114 - 119   2018.3

Renal function and risk of stroke and bleeding in patients undergoing catheter ablation for atrial fibrillation: Comparison between uninterrupted direct oral anticoagulants and warfarin administration.

Yanagisawa S, Inden Y, Fujii A, Ando M, Funabiki J, Murase Y, Takenaka M, Otake N, Ikai Y, Sakamoto Y, Shibata R, Murohara T

Heart rhythm   Vol. 15 ( 3 ) page： 348-354   2018.3

Early Prediction Model for Successful Bridge to Recovery in Patients With Fulminant Myocarditis Supported With Percutaneous Venoarterial Extracorporeal Membrane Oxygenation　- Insights From the CHANGE PUMP Study.

  Vol. 82 ( 3 ) page： 699-707   2018.2

Effects of Ezetimibe-Statin Combination Therapy on Coronary Atherosclerosis in Acute Coronary Syndrome.

Hibi K, Sonoda S, Kawasaki M, Otsuji Y, Murohara T, Ishii H, Sato K, Koshida R, Ozaki Y, Sata M, Morino Y, Miyamoto T, Amano T, Morita S, Kozuma K, Kimura K, Fujiwara H, Ezetimibe-ACS Investigators.

Circulation journal : official journal of the Japanese Circulation Society   Vol. 82 ( 3 ) page： 757-766   2018.2

Impact of high-density lipoprotein 3 cholesterol subfraction on periprocedural myocardial injury in patients who underwent elective percutaneous coronary intervention

Harada Kazuhiro, Kikuchi Ryosuke, Suzuki Susumu, Tanaka Akihito, Aoki Toshijiro, Iwakawa Naoki, Kojima Hiroki, Hirayama Kenshi, Mitsuda Takayuki, Sumi Takuya, Negishi Yosuke, Ishii Hideki, Murohara Toyoaki

LIPIDS IN HEALTH AND DISEASE   Vol. 17 ( 1 ) page： 21   2018.2

Clinical Characteristics of Nonobese Patients with Acute Coronary Syndrome and Increased Epicardial Fat Volume.

Harada K, Suzuki H, Matsunaga S, Onishi T, Nishikawa Y, Funakubo H, Mamiya K, Nagao T, Shinoda N, Sakai S, Kato M, Marui N, Ishii H, Amano T, Matsubara T, Murohara T

Journal of atherosclerosis and thrombosis     2018.2

Circulating ANGPTL2 Levels Increase in Humans and Mice Exhibiting Cardiac Dysfunction

Tian Zhe, Miyata Keishi, Morinaga Jun, Horiguchi Haruki, Kadomatsu Tsuyoshi, Endo Motoyoshi, Zhao Jiabin, Zhu Shunshun, Sugizaki Taichi, Sato Michio, Terada Kazutoyo, Okumura Takahiro, Murohara Toyoaki, Oike Yuichi

CIRCULATION JOURNAL   Vol. 82 ( 2 ) page： 437-+   2018.2

Head-to-head comparison of acute and chronic pulmonary vein stenosis for cryoballoon versus radiofrequency ablation.

Watanabe R, Sairaku A, Yoshida Y, Nanasato M, Kamiya H, Suzuki H, Ogura Y, Aoyama Y, Maeda M, Ando M, Eguchi S, Inden Y, Kihara Y, Murohara T

Pacing and clinical electrophysiology : PACE     2018.1

Long-Term Clinical Outcomes Survey of Bone Marrow-Derived Cell Therapy in Critical Limb Ischemia in Japan.

Kondo K, Yanishi K, Hayashida R, Shintani S, Shibata R, Murotani K, Ando M, Mizuno M, Fujiwara T, Murohara T, Matoba S, TACT Follow-up Study Investigators.

Circulation journal : official journal of the Japanese Circulation Society     2018.1

Clinical Outcomes after Isolated Infrapopliteal Revascularization in Hemodialysis Patients with Critical Limb Ischemia: Endovascular Therapy versus Bypass Surgery.

Ito R, Kumada Y, Ishii H, Kamoi D, Sakakibara T, Umemoto N, Takahashi H, Murohara T

Journal of atherosclerosis and thrombosis     2018.1

Coronary air embolism following transbronchial lung biopsy.

Sumi T, Tanaka A, Ishii H, Suzuki S, Kada K, Murohara T

Cardiovascular intervention and therapeutics     2018.1

Use of sodium-glucose cotransporter 2 inhibitors in older patients with type 2 diabetes mellitus.

Kambara T, Shibata R, Osanai H, Nakashima Y, Asano H, Sakai K, Murohara T, Ajioka M

Geriatrics & gerontology international   Vol. 18 ( 1 ) page： 108-114   2018.1

Double-Blind, Randomized, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Eplerenone in Japanese Patients With Chronic Heart Failure (J-EMPHASIS-HF)

Tsutsui Hiroyuki, Ito Hiroshi, Kitakaze Masafumi, Komuro Issei, Murohara Toyoaki, Izumi Tohru, Sunagawa Kenji, Yasumura Yoshio, Yano Masafumi, Yamamoto Kazuhiro, Yoshikawa Tsutomu, Tsutamoto Takayoshi, Zhang Junwei, Okayama Akifumi, Ichikawa Yoshihiko, Kanmuri Kazuhiro, Matsuzaki Masunori

CIRCULATION JOURNAL   Vol. 82 ( 1 ) page： 148-+   2018.1

Assessment of autonomic nervous system modulation after novel catheter ablation techniques for atrial fibrillation using multiple short-term electrocardiogram recordings

Yanagisawa Satoshi, Inden Yasuya, Fujii Aya, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Ikai Yoshihiro, Sakamoto Yusuke, Shibata Rei, Murohara Toyoaki

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY   Vol. 51 ( 1 ) page： 35 - 44   2018.1

Midkine Promotes Atherosclerotic Plaque Formation Through Its Pro-Inflammatory, Angiogenic and Anti-Apoptotic Functions in Apolipoprotein E-Knockout Mice

Takemoto Yoshio, Horiba Mitsuru, Harada Masahide, Sakamoto Kazuma, Takeshita Kyosuke, Murohara Toyoaki, Kadomatsu Kenji, Kamiya Kaichiro

CIRCULATION JOURNAL   Vol. 82 ( 1 ) page： 19-27   2018.1

The Selvester QRS score as a predictor of cardiac events in nonischemic dilated cardiomyopathy.

Hiraiwa H, Okumura T, Sawamura A, Sugiura Y, Kondo T, Watanabe N, Aoki S, Ichii T, Kitagawa K, Kano N, Fukaya K, Furusawa K, Morimoto R, Takeshita K, Bando YK, Murohara T

Journal of cardiology   Vol. 71 ( 3-4 ) page： 284 - 290   2018

The Selvester QRS score as a predictor of cardiac events in nonischemic dilated cardiomyopathy reply

Hiraiwa Hiroaki, Okumura Takahiro, Sawamura Akinori, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 72 ( 3-4 ) page： 266 - 266   2018

Anxiety and Depression among Hypertensive Outpatients in Afghanistan: A Cross-Sectional Study in Andkhoy City.

Hamrah MS, Hamrah MH, Ishii H, Suzuki S, Hamrah MH, Hamrah AE, Dahi AE, Takeshita K, Yisireyili M, Hamrah MH, Fotouhi A, Sakamoto J, Murohara T

International journal of hypertension   Vol. 2018   page： 8560835   2018

Urinary and circulating levels of the anti-angiogenic isoform of vascular endothelial growth factor-A in patients with chronic kidney disease

Kikuchi Ryosuke, Yasuda Yoshinari, Nakatochi Masahiro, Shibata Yohei, Hara Toshiaki, Suzuki Atsuo, Imaizumi Takahiro, Suzuki Susumu, Ishii Hideki, Takeshita Kyosuke, Matsushita Tadashi, Maruyama Shoichi, Murohara Toyoaki

CLINICA CHIMICA ACTA   Vol. 475   page： 102 - 108   2017.12

The combination assessment of lipid pool and thrombus by optical coherence tomography can predict the filter no-reflow in primary PCI for ST elevated myocardial infarction

Negishi Yosuke, Ishii Hideki, Suzuki Susumu, Aoki Toshijiro, Iwakawa Naoki, Kojima Hiroki, Harada Kazuhiro, Hirayama Kenshi, Mitsuda Takayuki, Sumi Takuya, Tanaka Akihito, Ogawa Yasuhiro, Kawaguchi Katsuhiro, Murohara Toyoaki

MEDICINE   Vol. 96 ( 50 ) page： e9297   2017.12

Development and Validation of a Novel Cuff-Less Blood Pressure Monitoring Device.

  Vol. 2 ( 6 ) page： 631-642   2017.12

Impact of post-dilatation on longitudinal stent elongation: An in vitro study.

Sumi T, Ishii H, Tanaka A, Suzuki S, Kojima H, Iwakawa N, Aoki T, Hirayama K, Mitsuda T, Harada K, Negishi Y, Ota T, Kada K, Murohara T

Journal of cardiology     2017.11

Angiotensin receptor blocker irbesartan reduces stress-induced intestinal inflammation via AT1a signaling and ACE2-dependent mechanism in mice.

Yisireyili M, Uchida Y, Yamamoto K, Nakayama T, Cheng XW, Matsushita T, Nakamura S, Murohara T, Takeshita K

Brain, behavior, and immunity     2017.11

Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells

Yisireyili Maimaiti, Takeshita Kyosuke, Saito Shinichi, Murohara Toyoaki, Niwa Toshimitsu

NAGOYA JOURNAL OF MEDICAL SCIENCE   Vol. 79 ( 4 ) page： 477-486   2017.11

Impact of Coronary Stent Fracture on Restenotic Neointimal Tissue Characterization After Drug-Eluting Stent Implantation An Integrated Backscatter Intravascular Ultrasound Study

Uchida Yasuhiro, Ichimiya Satoshi, Ishii Hideki, Oishi Hideo, Aoki Toshijiro, Miki Yusuke, Kawamiya Toshiki, Ichimiya Hitoshi, Watanabe Junji, Kanashiro Masaaki, Hayano Shinji, Suzuki Susumu, Amano Tetsuya, Matsubara Tatsuaki, Murohara Toyoaki

INTERNATIONAL HEART JOURNAL   Vol. 58 ( 6 ) page： 861-867   2017.11

Safety and Efficacy of Long-Term Use of Tolvaptan in Patients With Heart Failure and Chronic Kidney Disease

Uemura Yusuke, Shibata Rei, Takemoto Kenji, Uchikawa Tomohiro, Koyasu Masayoshi, Ishikawa Shinji, Imai Ryo, Ozaki Yuta, Watanabe Takashi, Teraoka Tsubasa, Watarai Masato, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 11 ) page： 1736-+   2017.11

Chronic Psychological Stress Accelerates Vascular Senescence and Impairs Ischemia-Induced Neovascularization: The Role of Dipeptidyl Peptidase-4/Glucagon-Like Peptide-1-Adiponectin Axis

Piao Limei, Zhao Guangxian, Zhu Enbo, Inoue Aiko, Shibata Rei, Lei Yanna, Hu Lina, Yu Chenglin, Yang Guang, Wu Hongxian, Xu Wenhu, Okumura Kenji, Ouchi Noriyuki, Murohara Toyoaki, Kuzuya Masafumi, Cheng Xian Wu

JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 6 ( 10 )   2017.10

Lipid-Lowering Therapy With Monoclonal Antibodies to Proprotein Convertase Subtilisin-Kexin Type 9. Lessons From Recent Clinical Trials

Ishii Hideki, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 10 ) page： 1386 - 1387   2017.10

Vasospastic angina in a 16-year-old female.

Sumi T, Tanaka A, Ishii H, Suzuki S, Oguri M, Murohara T

Cardiovascular intervention and therapeutics     2017.9

Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension

Tanabe Nobuhiro, Ikeda Satoshi, Tahara Nobuhiro, Fukuda Keiichi, Hatano Masaru, Ito Hiroshi, Nakayama Tomotaka, Anzai Toshihisa, Hashimoto Akiyoshi, Inoue Teruo, Kajinami Kouji, Kihara Yasuki, Kinoshita Hideyuki, Kuwahara Koichiro, Murohara Toyoaki, Okazaki Osamu, Sakai Satoshi, Satoh Toru, Takeda Yutaka, Takeishi Yasuchika, Taniguchi Mitsugu, Watanabe Hiroshi, Yamamoto Takeshi, Yamauchi-Takihara Keiko, Yoshioka Koichiro, Sasayama Shigetake

CIRCULATION JOURNAL   Vol. 81 ( 9 ) page： 1360-1367   2017.9

Different rate-dependent responses between J waves and the notches on an epicardial local electrogram in a patient with idiopathic ventricular fibrillation.

Kamikubo Y, Inden Y, Nagao T, Aizawa Y, Murohara T

HeartRhythm case reports   Vol. 3 ( 9 ) page： 427-430   2017.9

Sokolow-Lyon voltage is suitable for monitoring improvement in cardiac function and prognosis of patients with idiopathic dilated cardiomyopathy

Fukaya Kenji, Takeshita Kyosuke, Okumura Takahiro, Hiraiwa Hiroaki, Aoki Soichiro, Ichii Takeo, Sugiura Yuki, Kitagawa Katsuhide, Kondo Toru, Watanabe Naoki, Kano Naoaki, Furusawa Kenji, Sawamura Akinori, Morimoto Ryota, Bando Yasuko, Murohara Toyoaki

ANNALS OF NONINVASIVE ELECTROCARDIOLOGY   Vol. 22 ( 5 )   2017.9

Dynamics of angiogenesis in ischemic areas of the infarcted heart

Kobayashi Koichi, Maeda Kengo, Takefuji Mikito, Kikuchi Ryosuke, Morishita Yoshihiro, Hirashima Masanori, Murohara Toyoaki

SCIENTIFIC REPORTS   Vol. 7 ( 1 ) page： 7156   2017.8

Atorvastatin reduces cardiac and adipose tissue inflammation in rats with metabolic syndrome

Yamada Yuichiro, Takeuchi Shino, Yoneda Mamoru, Ito Shogo, Sano Yusuke, Nagasawa Kai, Matsuura Natsumi, Uchinaka Ayako, Murohara Toyoaki, Nagata Kohzo

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 240   page： 332 - 338   2017.8

Vagal response in cryoballoon ablation of atrial fibrillation and autonomic nervous system: Utility of epicardial adipose tissue location

Yanagisawa Satoshi, Inden Yasuya, Mizutani Yoshiaki, Fujii Aya, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Funabiki Junya, Murase Yosuke, Takenaka Masaki, Otake Noriaki, Hattori Tetsuyoshi, Shibata Rei, Murohara Toyoaki

JOURNAL OF ARRHYTHMIA   Vol. 33 ( 4 ) page： 275 - 282   2017.8

Does Treatment of Impaired Glucose Tolerance Improve Cardiovascular Outcomes in Patients with Previous Myocardial Infarction?

Asakura Masanori, Kim Jiyoong, Asanuma Hiroshi, Hamasaki Toshimitsu, Tsukahara Kengo, Higashino Yorihiko, Ishikawa Tetsuya, Nakama Yasuharu, Koba Shinji, Maruyama Yasuyuki, Tsujimoto Mitsuru, Himeno Hideo, Ohkusa Takanori, Fujino Susumu, Shimizu Makoto, Endo Tsutomu, Yoda Shunichi, Muroya Takahiro, Murohara Toyoaki, Ohte Nobuyuki, Suzuki Hiroshi, Kohno Tohru, Fukui Kazuki, Shiono Takaaki, Takase Hiroyuki, Uzui Hiroyasu, Nagai Yoshiyuki, Hashimoto Yuji, Ikeda Shuntaro, Mizuno Sumio, Tamita Koichi, Fujita Masashi, Satake Kazuo, Kinoshita Yoshihiko, Nunohiro Tatsuya, Sakagami Satoru, Higaki Jitsuo, Morii Isao, Sawada Reimin, Hiasa Yoshikazu, Shigemasa Tomohiko, Nakahama Makoto, Sata Masataka, Doi Osamu, Ueda Tetsuro, Yamada Takahisa, Yamanouchi Takayoshi, Yamaguchi Hajime, Morita Yukiko, Hayashi Hideki, Kitakaze Masafumi

CARDIOVASCULAR DRUGS AND THERAPY   Vol. 31 ( 4 ) page： 401-411   2017.8

Effects of mTOR inhibition on cardiac and adipose tissue pathology and glucose metabolism in rats with metabolic syndrome

Uchinaka Ayako, Yoneda Mamoru, Yamada Yuichiro, Murohara Toyoaki, Nagata Kohzo

PHARMACOLOGY RESEARCH & PERSPECTIVES   Vol. 5 ( 4 )   2017.8

Impact of drug-coated balloon in hemodialysis patients with in-stent-restenosis lesion

Umemoto N., Ishii H., Kamoi D., Sakakibara T., Aoyama T., Kitahara Y., Takahashi H., Murohara T.

EUROPEAN HEART JOURNAL   Vol. 38   page： 86-86   2017.8

Predictive value of abdominal aortic calcification index for the mid-term cardiovascular events among patients with acute coronary syndrome

Horibe H., Oishi H., Yamase Y., Ueyama C., Ikehara N., Akita N., Shigeta T., Yajima K., Hibino T., Kondo T., Kawamiya T., Suzuki S., Ishii H., Murohara T.

EUROPEAN HEART JOURNAL   Vol. 38   page： 130-131   2017.8

Correlations between geriatric nutritional risk index and peripheral artery disease in elderly coronary artery disease patients

Kawamiya Toshiki, Suzuki Susumu, Ishii Hideki, Hirayama Kenshi, Harada Kazuhiro, Shibata Yohei, Tatami Yosuke, Harata Shingo, Kawashima Kazuhiro, Kunimura Ayako, Takayama Yohei, Shimbo Yusaku, Osugi Naohiro, Yamamoto Dai, Ota Tomoyuki, Kono Chikao, Murohara Toyoaki

GERIATRICS & GERONTOLOGY INTERNATIONAL   Vol. 17 ( 7 ) page： 1057-1062   2017.7

Dipeptidyl Peptidase-4 Regulates Hematopoietic Stem Cell Activation in Response to Chronic Stress

Zhu Enbo, Hu Lina, Wu Hongxian, Piao Limei, Zhao Guangxian, Inoue Aiko, Kim Weon, Yu Chenglin, Xu Wenhu, Bando Yasuko K., Li Xiang, Lei Yanna, Hao Chang-Ning, Takeshita Kyosuke, Kim Woo-Shik, Okumura Kenji, Murohara Toyoaki, Kuzuya Masafumi, Cheng Xian Wu

JOURNAL OF THE AMERICAN HEART ASSOCIATION   Vol. 6 ( 7 )   2017.7

Decreased Serum Albumin Predicts Bleeding Events in Patients on Antiplatelet Therapy After Percutaneous Coronary Intervention

Tatami Yosuke, Ishii Hideki, Aoki Toshijiro, Harada Kazuhiro, Hirayama Kenshi, Shibata Yohei, Sumi Takuya, Negishi Yosuke, Kawashima Kazuhiro, Kunimura Ayako, Kawamiya Toshiki, Yamamoto Dai, Suzuki Susumu, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 7 ) page： 999 - 1005   2017.7

Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction

Tsuda Takuma, Takefuji Mikito, Wettschureck Nina, Kotani Kazuhiko, Morimoto Ryota, Okumura Takahiro, Kaur Harmandeep, Eguchi Shunsuke, Sakaguchi Teruhiro, Ishihama Sohta, Kikuchi Ryosuke, Unno Kazumasa, Matsushita Kunihiro, Ishikawa Shizukiyo, Offermanns Stefan, Murohara Toyoaki

JOURNAL OF EXPERIMENTAL MEDICINE   Vol. 214 ( 7 ) page： 1877-1888   2017.7

Role of Adipokines in Cardiovascular Disease

Lau Wayne Bond, Ohashi Koji, Wang Yajing, Ogawa Hayato, Murohara Toyoaki, Ma Xin-Liang, Ouchi Noriyuki

CIRCULATION JOURNAL   Vol. 81 ( 7 ) page： 920-928   2017.7

Usefulness of the Combination of In-Hospital Poor Diuretic Response and Systemic Congestion to Predict Future Cardiac Events in Patients With Acute Decompensated Heart Failure

Aoki Soichiro, Okumura Takahiro, Sawamura Akinori, Kitagawa Katsuhide, Morimoto Ryota, Sakakibara Masaki, Murohara Toyoaki

AMERICAN JOURNAL OF CARDIOLOGY   Vol. 119 ( 12 ) page： 2010-2016   2017.6

Comparison of Frequency and Characteristics of Patients With Atrial Fibrillation Having Ablation With Versus Without Coronary Narrowing (>= 50%) by Angiography

Tomomatsu Toshiro, Morishima Itsuro, Okumura Kenji, Tsuboi Hideyuki, Morita Yasuhiro, Takagi Kensuke, Yoshida Ruka, Nagai Hiroaki, Ikai Yoshihiro, Shibata Naoki, Tsuzuki Kazuhito, Sone Takahito, Murohara Toyoaki

AMERICAN JOURNAL OF CARDIOLOGY   Vol. 119 ( 11 ) page： 1770-1775   2017.6

Coronary artery calcification scores improve contrast-induced nephropathy risk assessment in chronic kidney disease patients

Osugi Naohiro, Suzuki Susumu, Shibata Yohei, Tatami Yosuke, Harata Shingo, Ota Tomoyuki, Hayashi Mutsuharu, Yasuda Yoshinari, Ishii Hideki, Shimizu Atsuya, Murohara Toyoaki

CLINICAL AND EXPERIMENTAL NEPHROLOGY   Vol. 21 ( 3 ) page： 391-397   2017.6

Diallyl Trisulfide Augments Ischemia-Induced Angiogenesis via an Endothelial Nitric Oxide Synthase-Dependent Mechanism

Hayashida Ryo, Kondo Kazuhisa, Morita Sumio, Unno Kazumasa, Shintani Satoshi, Shimizu Yuuki, Calvert John W., Shibata Rei, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 6 ) page： 870-878   2017.6

Novel therapy for pancreatic fistula using adipose-derived stem cell sheets treated with mannose

Kaneko Hirokazu, Kokuryo Toshio, Yokoyama Yukihiro, Yamaguchi Junpei, Yamamoto Tokunori, Shibata Rei, Gotoh Momokazu, Murohara Toyoaki, Ito Akira

SURGERY   Vol. 161 ( 6 ) page： 1561-1569   2017.6

New diagnostic index for sarcopenia in patients with cardiovascular diseases

Harada Haruhito, Kai Hisashi, Shibata Rei, Niiyama Hiroshi, Nishiyama Yasuhiro, Murohara Toyoaki, Yoshida Noriko, Katoh Atsushi, Ikeda Hisao

PLOS ONE   Vol. 12 ( 5 ) page： e0178123   2017.5

Effect of sitagliptin on the echocardiographic parameters of left ventricular diastolic function in patients with type 2 diabetes: a subgroup analysis of the PROLOGUE study

Yamada Hirotsugu, Tanaka Atsushi, Kusunose Kenya, Amano Rie, Matsuhisa Munehide, Daida Hiroyuki, Ito Masaaki, Tsutsui Hiroyuki, Nanasato Mamoru, Kamiya Haruo, Bando Yasuko K., Odawara Masato, Yoshida Hisako, Murohara Toyoaki, Sata Masataka, Node Koichi

CARDIOVASCULAR DIABETOLOGY   Vol. 16 ( 1 ) page： 63   2017.5

Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice

Yisireyili Maimaiti, Hayashi Motoharu, Wu Hongxian, Uchida Yasuhiro, Yamamoto Koji, Kikuchi Ryosuke, Hamrah Mohammad Shoaib, Nakayama Takayuki, Cheng Xian Wu, Matsushita Tadashi, Nakamura Shigeo, Niwa Toshimitsu, Murohara Toyoaki, Takeshita Kyosuke

SCIENTIFIC REPORTS   Vol. 7 ( 1 ) page： 1266   2017.4

Impact of Skeletal Muscle Mass on Long-Term Adverse Cardiovascular Outcomes in Patients With Chronic Kidney Disease

Harada Kazuhiro, Suzuki Susumu, Ishii Hideki, Aoki Toshijiro, Hirayama Kenshi, Shibata Yohei, Negishi Yosuke, Sumi Takuya, Kawashima Kazuhiro, Kunimura Ayako, Shimbo Yusaku, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Morimoto Ryota, Yasuda Yoshinari, Murohara Toyoaki

AMERICAN JOURNAL OF CARDIOLOGY   Vol. 119 ( 8 ) page： 1275-1280   2017.4

O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals

Sawaguchi Shogo, Varshney Shweta, Ogawa Mitsutaka, Sakaidani Yuta, Yagi Hirokazu, Takeshita Kyosuke, Murohara Toyoaki, Kato Koichi, Sundaram Subha, Stanley Pamela, Okajima Tetsuya

ELIFE   Vol. 6   2017.4

Trends in physiological coagulation factors in Japanese patients receiving novel oral anticoagulants

Nagao Tomoyuki, Hunakubo Hiroshi, Suzuki Mayu, Kataok Takashi, Okumura Satoshi, Shinoda Norihiro, Harada Ken, Kato Bunichi, Kato Masataka, Marui Nobuyuki, Sakai Shinichi, Amano Tetsuya, Murohara Toyoaki

JOURNAL OF ARRHYTHMIA   Vol. 33 ( 2 ) page： 117-121   2017.4

Impact of basal inferolateral scar burden determined by automatic analysis of Tc-99m-MIBI myocardial perfusion SPECT on the long-term prognosis of cardiac resynchronization therapy

Morishima Itsuro, Okumura Kenji, Tsuboi Hideyuki, Morita Yasuhiro, Takagi Kensuke, Yoshida Ruka, Nagai Hiroaki, Tomomatsu Toshiro, Ikai Yoshihiro, Terada Kazushi, Sone Takahito, Murohara Toyoaki

EUROPACE   Vol. 19 ( 4 ) page： 573-579   2017.4

The Association of Ankle Brachial Index, Protein-Energy Wasting, and Inflammation Status with Cardiovascular Mortality in Patients on Chronic Hemodialysis

Ishii Hideki, Takahashi Hiroshi, Ito Yasuhiko, Aoyama Toru, Kamoi Daisuke, Sakakibara Takashi, Umemoto Norio, Kumada Yoshitaka, Suzuki Susumu, Murohara Toyoaki

NUTRIENTS   Vol. 9 ( 4 )   2017.4

Impact of nutritional assessment and body mass index on cardiovascular outcomes in patients with stable coronary artery disease

Kunimura Ayako, Ishii Hideki, Uetani Tadayuki, Aoki Toshijirou, Harada Kazuhiro, Hirayama Kenshi, Negishi Yosuke, Shibata Yohei, Sumi Takuya, Kawashima Kazuhiro, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Suzuki Susumu, Amano Tetsuya, Murohara Toyoaki

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 230   page： 653-658   2017.3

Increased pre-procedural urinary microalbumin is associated with a risk for renal functional deterioration after coronary computed tomography angiography

Isobe Satoshi, Yuba Miyuki, Mori Hiroaki, Suzuki Susumu, Sato Kimihide, Ishii Hideki, Murohara Toyoaki

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 230   page： 599-603   2017.3

Assessment of left ventricular diastolic function during trastuzumab treatment in patients with HER2-positive breast cancer

Honda Kazunori, Takeshita Kyosuke, Murotani Kenta, Mitsuma Ayako, Hayashi Hironori, Tsunoda Nobuyuki, Kikumori Toyone, Murohara Toyoaki, Ando Yuichi

BREAST CANCER   Vol. 24 ( 2 ) page： 312-318   2017.3

Biphasic Force-Frequency Relation Predicts Primary Cardiac Events in Patients With Hypertrophic Cardiomyopathy

Morimoto Ryota, Okumura Takahiro, Bando Yasuko K., Fukaya Kenji, Sawamura Akinori, Kawase Haruya, Shimizu Shinya, Shimazu Shuzo, Hirashiki Akihiro, Takeshita Kyosuke, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 3 ) page： 368 - 375   2017.3

Association between plaque characteristics and the amount of debris captured by a filter-type distal protection device in patients with acute coronary syndrome

Kitagawa Katsuhide, Amano Tetsuya, Uetani Tadayuki, Ishii Hideki, Okumura Takahiro, Suzuki Susumu, Takashima Hiroaki, Kurita Akiyoshi, Ando Hirohiko, Matsubara Tatsuaki, Murohara Toyoaki

ATHEROSCLEROSIS   Vol. 258   page： 72-78   2017.3

Long-Term Pathological Follow-Up of Myocardium in a Carrier of Duchenne Muscular Dystrophy With Dilated Cardiomyopathy

Kondo Toru, Okumura Takahiro, Takefuji Mikito, Hiraiwa Hiroaki, Sugiura Yuki, Watanabe Naoki, Aoki Soichiro, Ichii Takeo, Kitagawa Katsuhide, Kano Naoaki, Fukaya Kenji, Furusawa Kenji, Sawamura Akinori, Morimoto Ryota, Bando Yasuko K., Takemura Genzou, Murohara Toyoaki

CIRCULATION-HEART FAILURE   Vol. 10 ( 3 ) page： e003826   2017.3

Nutrition Status Predicts Severity of Vascular Calcification in Non-Dialyzed Chronic Kidney Disease

Harada Kazuhiro, Suzuki Susumu, Ishii Hideki, Hirayama Kenshi, Aoki Toshijiro, Shibata Yohei, Negishi Yosuke, Sumi Takuya, Kawashima Kazuhiro, Kunimura Ayako, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Morimoto Ryota, Yasuda Yoshinari, Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 3 ) page： 316 - 321   2017.3

Asian Perspective of the EMPA-REG OUTCOME Study

Bando Yasuko K., Murohara Toyoaki

CIRCULATION JOURNAL   Vol. 81 ( 2 ) page： 155 - 157   2017.2

Impact of Paradoxical Decrease in High-density Lipoprotein Cholesterol Levels After Statin Therapy on Major Adverse Cardiovascular Events in Patients with Stable Angina Pectoris

Hirayama Kenshi, Ota Tomoyuki, Harada Kazuhiro, Shibata Yohei, Tatami Yosuke, Harata Shingo, Kawashima Kazuhiro, Kunimura Ayako, Shimbo Yusaku, Takayama Yohei, Kawamiya Toshiki, Yamamoto Dai, Osugi Naohiro, Suzuki Susumu, Ishii Hideki, Murohara Toyoaki

CLINICAL THERAPEUTICS   Vol. 39 ( 2 ) page： 279 - 287   2017.2

C1q/TNF-related protein 1 prevents neointimal formation after arterial injury

Kanemura Noriyoshi, Shibata Rei, Ohashi Koji, Ogawa Hayato, Hiramatsu-Ito Mizuho, Enomoto Takashi, Yuasa Daisuke, Ito Masanori, Hayakawa Satoko, Otaka Naoya, Murohara Toyoaki, Ouchi Noriyuki

ATHEROSCLEROSIS   Vol. 257   page： 138 - 145   2017.2

Association of renal function with clinical parameters and conditions in a longitudinal population-based epidemiological study

Sumi Takuya, Oguri Mitsutoshi, Fujimaki Tetsuo, Horibe Hideki, Kato Kimihiko, Matsui Kota, Takeuchi Ichiro, Murohara Toyoaki, Yamada Yoshiji

BIOMEDICAL REPORTS   Vol. 6 ( 2 ) page： 242-250   2017.2

Non-vitamin K antagonist oral anticoagulants versus warfarin for cardioversion of atrial fibrillation in clinical practice: A single-center experience

Shibata Naoki, Morishima Itsuro, Okumura Kenji, Morita Yasuhiro, Takagi Kensuke, Yoshida Ruka, Nagai Hiroaki, Tomomatsu Toshiro, Ikai Yoshihiro, Terada Kazushi, Tsuzuki Kazuhito, Tsuboi Hideyuki, Sone Takahito, Murohara Toyoaki

JOURNAL OF ARRHYTHMIA   Vol. 33 ( 1 ) page： 7-11   2017.2

Association of contrast-induced nephropathy with risk of adverse clinical outcomes in patients with cardiac catheterization: From the CINC-J study

Sato Akira, Aonuma Kazutaka, Watanabe Makoto, Hirayama Atsushi, Tamaki Nagara, Tsutsui Hiroyuki, Murohara Toyoaki, Ogawa Hisao, Akasaka Takashi, Yoshimura Michihiro, Takayama Tadateru, Sakakibara Mamoru, Suzuki Susumu, Ishigami Kenichi, Onoue Kenji, Saito Yoshihiko

INTERNATIONAL JOURNAL OF CARDIOLOGY   Vol. 227   page： 424-429   2017.1

Abnormal Circadian Blood Pressure Profile as a Prognostic Marker in Patients with Nonischemic Dilated Cardiomyopathy

Sawamura Akinori, Okumura Takahiro, Takeshita Kyosuke, Watanabe Naoki, Kano Naoaki, Mori Hiroaki, Fukaya Kenji, Morimoto Ryota, Hirashiki Akihiro, Bando Yasuko Kureishi, Murohara Toyoaki

CARDIOLOGY   Vol. 136 ( 1 ) page： 1 - 9   2017

Influence of False Lumen Status on the Prognosis of Acute Type A Aortic Dissection without Urgent Surgical Treatment

Tanaka Akihito, Ishii Hideki, Suzuki Susumu, Ota Tomoyuki, Oshima Hideki, Usui Akihiko, Komori Kimihiro, Murohara Toyoaki

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   Vol. 24 ( 2 ) page： 169 - 175   2017

Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A potential effect of non-pulmonary vein foci

Yanagisawa Satoshi, Inden Yasuya, Kato Hiroyuki, Fujii Aya, Mizutani Yoshiaki, Ito Tadahiro, Kamikubo Yosuke, Kanzaki Yasunori, Ando Monami, Hirai Makoto, Shibata Rei, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 69 ( 1-2 ) page： 3-10   2017

Impact of Renal Functional/Morphological Dynamics on the Calcification of Coronary and Abdominal Arteries in Patients with Chronic Kidney Disease

Ichii Takeo, Morimoto Ryota, Okumura Takahiro, Ishii Hideki, Tatami Yosuke, Yamamoto Dai, Aoki Soichiro, Hiraiwa Hiroaki, Furusawa Kenji, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Suzuki Susumu, Yasuda Yoshinari, Murohara Toyoaki

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   Vol. 24 ( 11 ) page： 1092 - 1104   2017

Impact of red blood cell distribution width on non-cardiac mortality in patients with acute decompensated heart failure with preserved ejection fraction

Imai Ryo, Uemura Yusuke, Okumura Takahiro, Takemoto Kenji, Uchikawa Tomohiro, Koyasu Masayoshi, Ishikawa Shinji, Iwamiya Satoshi, Ozaki Yuta, Shibata Rei, Watarai Masato, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 70 ( 5-6 ) page： 591-597   2017

Impact of Geriatric Nutritional Risk Index on cardiovascular outcomes in patients with stable coronary artery disease

Kunimura Ayako, Ishii Hideki, Uetani Tadayuki, Aoki Toshijirou, Harada Kazuhiro, Hirayama Kenshi, Negishi Yosuke, Shibata Yohei, Sumi Takuya, Kawashima Kazuhiro, Tatami Yosuke, Kawamiya Toshiki, Yamamoto Dai, Suzuki Susumu, Amano Tetsuya, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 69 ( 1-2 ) page： 383-388   2017

Effect of Body Mass Index on Posttonsillectomy Hemorrhage

Hoshino Tetsuro, Tanigawa Tohru, Yanohara Gen, Murotani Kenta, Horibe Yuichiro, Murohara Toyoaki, Shibata Rei, Ueda Hiromi

BIOMED RESEARCH INTERNATIONAL   Vol. 2017   page： 9610267   2017

Early Spontaneous Remission of Intramyocardial Dissecting Hematoma

Miura Ayako, Uemura Yusuke, Takemoto Kenji, Uchikawa Tomohiro, Koyasu Masayoshi, Ishikawa Shinji, Mitsuda Takayuki, Imai Ryo, Iwamiya Satoshi, Ozaki Yuta, Watanabe Takashi, Watarai Masato, Ishii Hideki, Murohara Toyoaki

INTERNAL MEDICINE   Vol. 56 ( 9 ) page： 1067-1070   2017

Circulatory power and ventilatory power over time under goal-oriented sequential combination therapy for pulmonary arterial hypertension

Hirashiki Akihiro, Adachi Shiro, Nakano Yoshihisa, Kamimura Yoshihiro, Shimokata Shigetake, Takeshita Kyosuke, Shimizu Atsuya, Toba Kenji, Murohara Toyoaki, Kondo Takahisa

PULMONARY CIRCULATION   Vol. 7 ( 2 ) page： 448-454   2017

Cholesterol metabolism as a prognostic marker in patients with mildly symptomatic nonischemic dilated cardiomyopathy

Sawamura Akinori, Okumura Takahiro, Hiraiwa Hiroaki, Aoki Soichiro, Kondo Toru, Ichii Takeo, Furusawa Kenji, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Morimoto Ryota, Bando Yasuko K., Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 69 ( 5-6 ) page： 888 - 894   2017

Left main coronary artery compression by a dilated main pulmonary artery and left coronary sinus of Valsalva aneurysm in a patient with heritable pulmonary arterial hypertension and FLNA mutation

Hirashiki Akihiro, Adachi Shiro, Nakano Yoshihisa, Kamimura Yoshihiro, Ogo Takeshi, Nakanishi Norifumi, Morisaki Takayuki, Morisaki Hiroko, Shimizu Atsuya, Toba Kenji, Murohara Toyoaki, Kondo Takahisa

PULMONARY CIRCULATION   Vol. 7 ( 3 ) page： 734-740   2017

The role of adipokines in cardiovascular disease

Shibata Rei, Ouchi Noriyuki, Ohashi Koji, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 70 ( 3-4 ) page： 329 - 334   2017

Relationship between pre-procedural microalbuminuria and renal functional changes after coronary computed tomography in diabetic patients

Isobe Satoshi, Yamada Takashi, Yuba Miyuki, Hayashi Mutsuharu, Ishii Hideki, Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 69 ( 3-4 ) page： 666-670   2017

Predictive Value of Aortic Valve Calcification for Periprocedural Myocardial Injury in Patients Undergoing Percutaneous Coronary Intervention

Shibata Yohei, Ishii Hideki, Suzuki Susumu, Tanaka Akihito, Tatami Yosuke, Harata Shingo, Ota Tomoyuki, Shimbo Yusaku, Takayama Yohei, Kunimura Ayako, Hirayama Kenshi, Harada Kazuhiro, Osugi Naohiro, Murohara Toyoaki

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   Vol. 24 ( 5 ) page： 487 - 494   2017

Myocardial contractile reserve predicts left ventricular reverse remodeling and cardiac events in dilated cardiomyopathy

Morimoto Ryota, Okumura Takahiro, Hirashiki Akihiro, Ishii Hideki, Ichii Takeo, Aoki Soichiro, Furusawa Kenji, Hiraiwa Hiroaki, Kondo Toru, Watanabe Naoki, Kano Naoaki, Fukaya Kenji, Sawamura Akinori, Takeshita Kyosuke, Bando Yasuko K., Murohara Toyoaki

JOURNAL OF CARDIOLOGY   Vol. 70 ( 3-4 ) page： 303 - 309   2017

Monitoring of anti-Xa activity and factors related to bleeding events: A study in Japanese patients with nonvalvular atrial fibrillation receiving rivaroxaban

Sakaguchi Teruhiro, Osanai Hiroyuki, Murase Yosuke, Ishii Hideki, Nakashima Yoshihito, Asano Hiroshi, Suzuki Susumu, Takefuji Mikito, Inden Yasuya, Sakai Kazuyoshi, Murohara Toyoaki, Ajioka Masayoshi

JOURNAL OF CARDIOLOGY   Vol. 70 ( 3-4 ) page： 244-249   2017

Dipeptidyl Peptidase 4 Inhibition Alleviates Shortage of Circulating Glucagon-Like Peptide-1 in Heart Failure and Mitigates Myocardial Remodeling and Apoptosis via the Exchange Protein Directly Activated by Cyclic AMP 1/Ras-Related Protein 1 Axis. Reviewed

Aoyama M, Kawase H, Bando YK, Monji A, Murohara T.

Circulation Heart Fail     page： ,,   2016

Wnt11 Gene Therapy with Adeno-associated Virus 9 Improves Recovery from Myocardial Infarction by Modulating the Inflammatory Response. Reviewed

Morishita Y, Kobayashi K, Klyachko E, Jujo K, Maeda K, Losordo DW, Murohara T.

Sci. Rep   Vol. 6   page： 21705   2016

The Effect of Sitagliptin on Carotid Artery Atherosclerosis in Type 2 Diabetes: The PROLOGUE Randomized Controlled Trial. Reviewed

685. Oyama J, Murohara T, Kitakaze M, Ishizu T, Sato Y, Kitagawa K, Kamiya H, Ajioka M, Ishihara M, Dai K, Nanasato M, Sata M, Maemura K, Tomiyama H, Higashi Y, Kaku K, Yamada H, Matsuhisa M, Yamashita K, Bando YK, Kashihara N, Ueda S, Inoue T, Tanaka A, Node K; PROLOGUE Study Investigators.

PLoS Med.   Vol. 2016 ( 13 ) page： e1002051   2016

Akt-girdin signaling in cancer-associated fibroblasts contributes to tumor progression Reviewed

Yamamura Y, Asai N, Enomoto A, Kato T, Mii S, Kondo Y, Ushida K, Niimi K, Tsunoda N, Nagino M, Ichihara S, Furukawa K, Maeda K, Murohara T, Takahashi M.

Cancer Res   Vol. 75   page： 813-823   2015

Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Reviewed

Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, Shi MA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P, Libby P, Shi GP.

Nature Medicine   Vol. 21   page： 820-826.   2015

East Asian variant of aldehyde dehydrogenase 2 (ALDH2*2) is associated with coronary spastic angina: possible roles of reactive aldehydes and implications of alcohol flushing syndrome. Reviewed

Mizuno Y, Harada E, Morita S, Kinoshita K, Hayashida M, Shono M, Morikawa Y, Murohara T, Nakayama M, Yoshimura M, Yasue H.

Circulation   Vol. 131   page： 1665-1673   2015

Neuron-Derived Neurotrophic Factor Ameliorates Adverse Cardiac Remodeling After Experimental Myocardial Infarction. Reviewed

Joki Y, Ohashi K, Yuasa D, Shibata R, Kataoka Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Kanemura N, Ito M, Ogawa H, Daida H, Murohara T, Ouchi N.

Circulation Heart Failure   Vol. 8   page： 342-351   2015

Wnt11 gene therapy with Adeno-associated Virus 9 improves the survival of mice with myocarditis induced by coxsackievirus B3 through the suppression of the inflammatory reaction. Reviewed

Aoyama Y, Kobayashi K, Morishita Y, Maeda K, Murohara T.

  Vol. 84   page： 45-51   2015

Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion. Reviewed

Yamaguchi S, Shibata R, Yamamoto N, Nishikawa M, Hibi H, Tanigawa T, Ueda M, Murohara T, Yamamoto A.

Sci. Rep.   Vol. 5   2015

C1q/TNF-related protein 9 protects against acute myocardial injury through an AdipoR1-AMPK dependent mechanism. Reviewed

Kambara T, Shibata R, Ohashi K, Matsuo K, Hiramatsu-Ito M, Enomoto T, Yuasa D, Ito M, Hayakawa S, Ogawa H, Aprahamian T, Walsh K, Murohara T, Ouchi N.

Mol. Cell. Biol.   Vol. 35   page： 2173-2185   2015

New endoplasmic reticulum stress regulator, Gipie, regulates the survival of vascular smooth muscle cells and the neointima formation after vascular injury. Reviewed

Noda T, Maeda K, Hayano S, Asai N, Enomoto A, Takahashi M, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 35   page： 1246-1253   2015

An anti-angiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Reviewed

Kikuchi R, Nakamura K, MacLauchian S, Shimizu I, Fuster JJ, Katanasaka Y, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Bates DO, Hamburg NM, Walsh K.

Nature Medicine   Vol. 20   page： 1464-1471   2014

Vildagliptin stimulates endothelial cell network formation and ischemia-induced revascularization via an endothelial nitric oxide synthase-dependent mechanism. Reviewed

Ishii M, Shibata R, Kondo K, Kambara T, Shimizu Y, Tanigawa T, Bando YK, Nishimura M, Ouchi N, Murohara T.

J. Biol. Chem.   Vol. 289   page： 27235-27245   2014

Adiponectin-mediated modulation of lymphatic vessel formation and lymphedema Reviewed

Shimizu Y, Shibata R, Ishii M, Ohashi K, Kambara T, Uemura Y, Yuasa D, Kataoka Y, Kihara S, Murohara T, Ouchi N.

J. Am. Heart Assoc.   Vol. 2   page： e000438   2013

Evidence for the importance of adiponectin in the cardioprotective effects of pioglitazone. Reviewed

Li P, Shibata R, Unno K, Shimano M, Furukawa M, Ohashi T, Cheng X, Nagata K, Ouchi N, Murohara T

Hypertension   Vol. 55 ( 1 ) page： 69-75   2010.5

*Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis. Reviewed

Kondo K, Shintani S, Shibata R, Murakami H, Murakami R, Imaizumi T, Kitagawa S, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 29   page： 61-66   2009

Autologous adipose-derived regenerative cells for therapeutic angiogenesis. Invited Reviewed

Murohara T, Shintani S, Kondo T.

Curr. Pharm. Des.   Vol. 15   page： 2784-2790   2009

Intracoronary electrocardiogram recording with a bare-wire system: perioperative ST-segment elevation in the intracoronary electrocardiogram Is associated with myocardial injury after elective coronary stent implantation. Reviewed

Uetani T, Amano T, Kumagai S, Ando H, Yokoi K, Yoshida T, Kato B, Kato M, Marui N, Nanki M, Matsubara T, Ishii H, Izawa H, Murohara T.

JACC. Cardiovasc. Interv.   Vol. 2   page： 127-135   2009

Differentiation capacity of endothelial progenitor cells correlates with endothelial function in healthy young men. Reviewed

Miura M, Numaguchi Y, Ishii M, Kubota R, Takeuchi T, Imamura A, Murakami R, Kondo T, Okumura K, Murohara T.

Circ J.   Vol. 73   page： 1324-1329   2009

Gamma-secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice. Reviewed

Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T.

Biochem. Biophys. Res. Commun.   Vol. 383   page： 216-221   2009

Mesenchymal stem cell-based gene therapy with prostacyclin synthase enhanced neovascularization in hindlimb ischemia. Reviewed

Ishii M, Numaguchi Y, Okumura K, Kubota R, Ma X, Murakami R, Naruse K, Murohara T.

Atherosclerosis   Vol. 206   page： 109-118   2009

Autologous adipose tissue as a new source of progenitor cells for therapeutic angiogenesis. Invited Reviewed

Murohara T

J. Cardiol.   Vol. 53   page： 155-163   2009

Renal protective effects and the prevention of contrast-induced nephropathy by atrial natriuretic peptide. Reviewed

Morikawa S, Sone T, Tsuboi H, Mukawa H, Morishima I, Uesugi M, Morita Y, Numaguchi Y, Okumura K, Murohara T.

J. Am. Coll. Cardiol.   Vol. 53   page： 1040-1046   2009

Molecular imaging of matrix metalloproteinase expression in atherosclerotic plaques of mice deficient in apolipoprotein e or low-density-lipoprotein receptor. Reviewed

Ohshima S, Petrov A, Fujimoto S, Zhou J, Azure M, Edwards DS, Murohara T, Narula N, Tsimikas S, Narula J.

J. Nucl. Med.   Vol. 50   page： 612-617   2009

Adiponectin and cardiovascular disease. Reviewed

Shibata R, Ouchi N, Murohara T.

Circ J   Vol. 73   page： 608-614   2009

Uric acid and left ventricular hypertrophy in Japanese men. Reviewed

Mitsuhashi H, Yatsuya H, Matsushita K, Zhang H, Otsuka R, Muramatsu T, Takefuji S, Hotta Y, Kondo T, Murohara T, Toyoshima H, Tamakoshi K.

Circ. J.   Vol. 73   page： 632-638   2009

Restored cardiac conditions and left ventricular function after parathyroidectomy in a hemodialysis patient. Reviewed

Nanasato M, Goto N, Isobe S, Unno K, Hirayama H, Sato T, Matsuoka S, Nagasaka T, Tominaga Y, Uchida K, Murohara T.

Circ. J.   Vol. 73   page： 1956-1960   2009

Rho-kinase contributes to sustained RhoA activation through phosphorylation of p190A RhoGAP. Reviewed

Mori K, Amano M, Takefuji M, Kato K, Morita Y, Nishioka T, Matsuura Y, Murohara T, Kaibuchi K.

J. Biol. Chem.   Vol. 284   page： 5067-5076   2009

*Caloric restriction stimulates revascularization in response to ischemia via adiponectin-mediated activation of eNOS. Reviewed

Kondo M, Shibata R, Miura R, Shimano M, Kondo K, Li P, Ohashi T, Kihara S, Maeda N, Walsh K, Ouchi N, Murohara T.

J. Biol. Chem.   Vol. 284   page： 1718-1724   2009

Aortic valvular calcification predicts restenosis after implantation of drug-eluting stents in patients on chronic haemodialysis. Reviewed

Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Amano T, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T.

Nephrol. Dial. Transplant.   Vol. 24   page： 1562-1567   2009

Role of bradykinin, nitric oxide and angiotensin II type 2 receptor in imidapril-induced angiogenesis. Reviewed

Li P, Kondo T, Numaguchi Y, Kobayashi K, Aoki M, Inoue N, Murohara T.

Hypertension   Vol. 51   page： 252-258   2008

Abnormal glucose regulation is associated with lipid rich coronary plaque: relationship to insulin resistance. Reviewed

Amano T, Matsubara T, Uetani T, Nanki M, Marui N, Kato M, Yoshida T, Arai K, Yokoi K, Ando H, Kumagai S, Ishii H, Izawa H, Hotta N, Murohara T.

JACC. Cardiovasc. Imaging.   Vol. 1   page： 39-45   2008

*Pharmacological intervention for prevention of left ventricular remodeling and improving prognosis in myocardial infarction. Reviewed

Ishii H, Amano T, Matsubara T, Murohara T.

Circulation   Vol. 118   page： 2710-2718   2008

Long-term clinical outcome after intramuscular implantation of bone marrow mononuclear cells (Therapeutic Angiogenesis by Cell Transplantation [TACT] trial) in patients with chronic limb ischemia. Reviewed

Matoba S, Tatsumi T, Murohara T, Imaizumi T, Katsuda Y, Ito M, Saito Y, Uemura S, Suzuki H, Fukumoto S, Yamamoto Y, Onodera R, Teramukai S, Fukushima M, Matsubara H; TACT Follow-up Study Investigators.

Am. Heart J.   Vol. 156   page： 1010-1018   2008

*Nifedipine improves endothelial function: role of endothelial progenitor cell. Reviewed

Sugiura T, Kondo T, Kureishi-Bando Y, Numaguchi Y, Yoshida O, Dohi Y, Kimura G, Ueda R, Rabelink TJ, Murohara T

Hypertension.   Vol. 52   page： 491-498   2008

Circulating adiponectin levels in patients with atrial fibrillation. Reviewed

Shimano M, Shibata R, Tsuji Y, Kamiya H, Uchikawa T, Harata S, Muto M, Ouchi N, Inden Y, Murohara T.

Circ. J.   Vol. 72   page： 1120-1124   2008

The correlation between lipid volume in the target lesion, measured by integrated backscatter intravascular ultrasound, and post-procedural myocardial infarction in patients with elective stent implantation. Reviewed

Uetani T, Amano T, Ando H, Yokoi K, Arai K, Kato M, Marui N, Nanki M, Matsubara T, Ishii H, Izawa H, Murohara T.

Eur. Heart J.   Vol. 29   page： 1714-1720   2008

Adiponectin promotes endothelial progenitor cell number and function. Reviewed

Shibata R, Skurk C, Ouchi N, Galasso G, Kondo K, Ohashi T, Kihara S, Murohara T, Walsh K.

FEBS Lett.   Vol. 582   page： 1607-1612   2008

Cilostazol improves long-term patency after percutaneous transluminal angioplasty in hemodialysis patients with peripheral artery disease. Reviewed

Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Yamada S, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T.

Clin. J. Am. Soc. Nephrol.   Vol. 3   page： 1034-1040   2008

*Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin. Reviewed

Kitamura T, Asai N, Enomoto A, Maeda K, Kato T, Ishida M, Jiang P, Watanabe T, Usukura J, Kondo T, Costantini F, Murohara T, Takahashi M.

Nat. Cell Biol.   Vol. 10   page： 329-337   2008

Angiopoietin-related growth factor enhances blood flow via activation of the ERK1/2-eNOS-NO pathway in a mouse hind-limb ischemia model. Reviewed

Urano T, Ito Y, Akao M, Sawa T, Miyata K, Tabata M, Morisada T, Hato T, Yano M, Kadomatsu T, Yasunaga K, Shibata R, Murohara T, Akaike T, Tanihara H, Suda T, Oike Y.

Arterioscler. Thromb. Vasc. Biol.   Vol. 28   page： 827-834   2008

Construction of multilayered cardiomyocyte sheets using magnetite nanoparticles and magnetic force. Reviewed

Shimizu K, Ito A, Lee JK, Yoshida T, Miwa K, Ishiguro H, Numaguchi Y, Murohara T, Kodama I, Honda H.

Biotechnol. Bioeng.   Vol. 96   page： 803-809   2007

Angiotensin II receptor blocker inhibits neointimal hyperplasia through regulation of smooth muscle-like progenitor cells. Reviewed

Yamada T, Kondo T, Numaguchi Y, Tsuzuki M, Matsubara T, Manabe I, Sata M, Nagai R, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 27   page： 2363-2369   2007

Effect of autologous bone marrow cell transplantation on ischemic ulcer in patients with Burger's disease. Reviewed

Saito Y, Sasaki K, Katsuda Y, Murohara T, Takeshita Y, Okazaki T, Arima K, Katsuki Y, Shintani S, Shimada T, Akashi H, Ikeda H, Imaizumi T.

Circ. J.   Vol. 71   page： 1187-1192.   2007

High-sensitivity C-reactive protein is quite low in Japanese men at high coronary risk. Reviewed

Matsushita K, Yatsuya H, Tamakoshi K, Yang PO, Otsuka R, Wada K, Mitsuhashi H, Hotta Y, Kondo T, Murohara T, Toyoshima H.

Circ J.   Vol. 71   page： 820-825   2007

Adiponectin level and left ventricular hypertrophy in Japanese men. Reviewed

Mitsuhashi H, Yatsuya H, Tamakoshi K, Matsushita K, Otsuka R, Wada K, Sugiura K, Takefuji S, Hotta Y, Kondo T, Murohara T, Toyoshima H.

Hypertension.   Vol. 49   page： 1448-1454   2007

A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. Reviewed

Ichihara S, Yamada Y, Ichihara G, Nakajima T, Li P, Kondo T, Gonzales FJ, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 27   page： 1297-1304   2007

Prevalence and severity of left atrial edema detected by electron beam tomography early after pulmonary vein ablation. Reviewed

Okada T, Yamada T, Murakami Y, Yoshida N, Ninomiya Y, Shimizu T, Toyama J, Yoshida Y, Ito T, Tsuboi N, Kondo T, Inden Y, Hirai M, Murohara T.

J. Am. Coll. Cardiol.   Vol. 49   page： 1436-1442   2007

Efficacy of oral nicorandil in patients with end-stage renal disease: a retrospective chart review after coronary angioplasty in Japanese patients receiving hemodialysis. Reviewed

Ishii H, Toriyama T, Aoyama T, Takahashi H, Yamada S, Kasuga H, Ichimiya S, Kanashiro M, Mitsuhashi H, Maruyama S, Matsuo S, Naruse K, Matsubara T, Murohara T.

Clin. Ther.   Vol. 29   page： 110-122   2007

Impact of metabolic syndrome on tissue characteristics of angiographically mild to moderate coronary lesions: Integrated backscatter intravascular ultrasound study. Reviewed

Amano T, Matsubara T, Uetani T, Nanki M, Marui N, Kato M, Arai K, Yokoi K, Ando H, Ishii H, Izawa H, Murohara T.

J. Am. Coll. Cardiol.   Vol. 49   page： 1149-1156   2007

Mechanisms underlying the impairment of ischemia-induced neovascularization in MMP-2-deficient mice. Reviewed

Cheng XW, Kuzuya M, Nakamura K, Maeda K, Tsuzuki M, Kim W, Sasaki T, Liu Z, Inoue N, Kondo T, Jin H, Numakuchi Y, Okumura K, Yokota M, Iguchi A, Murohara T.

Circ. Res.   Vol. 100   page： 904-913   2007

Rro-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation. Reviewed

Takefuji M, Mori K, Morita Y, Arimura N, Nishimura T, nakayama M, Hoshino M, Iwamatsu A, Murohara T, kaibuchi K, Amano M.

Biochem. Biophys. Res. Commun.   Vol. 355   page： 788-794   2007

Safety and efficacy of autologous progenitor cell transplantation for therapeutic angiogenesis in patients with critical limb ischemia. Reviewed

Kajiguchi M, Kondo T, Izawa H, Kobayashi K, Yamamoto K, Shintani S, Numaguchi Y, Naoe T, Takamatsu J, Komori K, Murohara T.

Circ. J.   Vol. 71   page： 196-201   2007

Depletion of endothelial progenitor cells in the peripheral blood of patients with ulcerative colitis. Reviewed

Masuda J, Mitsuyama K, Yamasaki H, Takedatsu H, Okamura T, Andoh A, Murohara T, Asahara T, Sata M.

Int. J. Mol. Med.   Vol. 19   page： 221-228   2007

Therapeutic angiogenesis using novel vascular endothelial growth factor-E/human placental growth factor chimera genes. Reviewed

Inoue N, Kondo T, Kobayashi K, Aoki M, Numaguchi Y, Shibuya M, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 27   page： 99-105   2007

A strategy of retrograde injection of bone marrow mononuclear cells into the myocardium for the treatment of ischemic heart disease. Reviewed

Yokoyama S, Fukuda N, Li Y, Hagikura K, Takayama T, Kunimoto S, Honye J, Saito S, Wada M, Satomi A, Kato M, Mugishima H, Kusumi Y, Mitsumata M, Murohara T.

J. Mol. Cell. Cardiol.   Vol. 40   page： 24-34   2006

Effects of receipt of chronic statin therapy before the onset of acute myocardial infarction: A retrospective study in patients with primary percutaneous coronary intervention. Reviewed

Ishii H, Ichimiya S, Kanashiro M, Aoyama T, Ogawa Y, Murakami R, Amano T, Naruse K, Matsubara T, Murohara T.

Clin. Ther.   Vol. 28   page： 1812-1819   2006

Clinical Protocol: Angiogenesis by Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells in Patients with Severe Coronary Artery Disease. TACT-NAGOYA-HEART. Reviewed

Izawa H, Kondo T, Usui A, Yamamoto K, Shintani S, Inden Y, Isobe S, Unno K, Kajiguchi M, Noda A, Yokota M, Takamatsu J, Ueda Y, Komori K, Murohara T.

Circ. J.   Vol. 70   page： 1180-1183   2006

l-Caldesmon regulates proliferation and migration of vascular smooth muscle cells and inhibits neointimal formation after angioplasty. Reviewed

Yokouchi K, Numaguchi Y, Okumura K, Ishii M, Kubota R, Imai H, Murakami R, Kondo T, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 26   page： 2231-2237   2006

Evaluation of compliance and stiffness of decellularized tissues as scaffolds for tissue-engineered small caliber vascular grafts using intravascular ultrasound. Reviewed

Murase Y, Narita Y, Kagami H, Miyamoto K, Ueda Y, Ueda M, Murohara T.

ASAIO J.   Vol. 52   page： 450-455   2006

Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers. Reviewed

Kim W, Jeong MH, Cho SH, Yun JH, Chae HJ, Ahn YK, Lee MC, Cheng X, Kondo T, Murohara T, Kang JC.

Circ. J.   Vol. 70   page： 1052-1057   2006

The prostacyclin analog, beraprost sodium, augments the efficacy of therapeutic angiogenesis induced by autologous bone marrow cells. Reviewed

Otsuka H, Akashi H, Murohara T, Okazaki T, Shintani S, Tayama K, Sasaki K, Imaizumi T, Aoyagi S.

Ann. Vasc. Surg.   Vol. 20   page： 646-652   2006

Comparison of percutaneous coronary intervention with medication in the treatment of coronary artery disease in hemodialysis patients. Reviewed

Yasuda K, Kasuga H, Aoyama T, Takahashi H, Toriyama T, Kawade Y, Iwashima S, Yamada S, Kawahara H, Maruyama S, Yuzawa Y, Ishii H, Murohara T, Matsuo S.

J. Am. Soc. Nephrol.   Vol. 17   page： 2322-2332   2006

The impact of the capability of circulating progenitor cell to differentiate on myocardial salvage in patients with primary acute myocardial infarction. Reviewed

Numaguchi Y, Sone T, Okumura K, Morita Y, Kubota R, Yokouchi K, Imai H, Harada M, Kondo T, Murohara T.

Circulation.   Vol. 114   page： I114-I119   2006

Plasma atrial natriuretic peptide and brain natriuretic peptide levels after radiofrequency catheter ablation of atrial fibrillation. Reviewed

Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T.

Am. J. Cardiol.   Vol. 97   page： 1741-1744   2006

Usefulness of esophageal leads for determining the strategy of pulmonary vein ablation to avoid complications associated with the esophagus. Reviewed

Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T.

Am. J. Cardiol.   Vol. 97   page： 1494-1497   2006

Combination therapy using angiopoietin-1 plasmid gene and autologous bone marrow cell implantation promotes functional angiogenesis. Reviewed

Kobayashi K, Kondo T, Inoue N, Aoki M, Mizuno M, Komori K, Yoshida J, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 26   page： 1465-1472   2006

Ischemia-induced angiogenesis: role of inflammatory response mediated by P-selectin. Reviewed

Egami K, Murohara T, Aoki M, Matsuishi T.

J. Leukoc. Biol.   Vol. 79   page： 971-976   2006

Incidence, location, and cause of recovery of electrical connections between the pulmonary veins and the left atrium after pulmonary vein isolation. Reviewed

Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T.

Europace.   Vol. 83   page： 182-188   2006

Klotho gene polymorphism may be a genetic risk factor for atherosclerotic coronary artery disease but not for vasospastic angina in Japanese. Reviewed

Imamura A, Okumura K, Ogawa Y, Murakami R, Torigoe M, Numaguchi Y, Murohara T.

Clin. Chim. Acta.   Vol. 371   page： 66-70   2006

Electrophysiological pulmonary vein antrum isolation with a multielectrode basket catheter is feasible and effective for curing paroxysmal atrial fibrillation: Efficacy of minimally extensive pulmonary vein isolation. Reviewed

Yamada T, Murakami Y, Okada T, Okamoto M, Shimizu T, Toyama J, Yoshida Y, Tsuboi N, Ito T, Muto M, Kondo T, Inden Y, Hirai M, Murohara T.

Heart Rhythm.   Vol. 3(Suppl.)   page： 377-384   2006

Peroxisome proliferators-activated receptor a activation, in addition to carnitine supplementation, rescues the detrimental lipotoxic cardiomyopathy due to disorder of fatty acid oxidation in a murine model of systemic carnitine deficiency. Reviewed

Asai T, Okumura K, Takahashi R, Matsui H, Numaguchi Y, Murakami H, Murakami R, Murohara T.

Cardiovasc. Res.   Vol. 70   page： 566-577   2006

Impact of plasma aldosterone levels for prediction of in-stent restenosis. Reviewed

Amano T, Matsubara T, Izawa H, Torigoe M, Yoshida T, Hamaguchi Y, Ishii H, Miura M, Hayashi Y, Ogawa Y, Murohara T.

Am. J. Cardiol.   Vol. 97   page： 785-788   2006

Synergistic effect of combined intramyocardial CD34 cells and VEGF-2 gene therapy post-myocardial infarction. Reviewed

Shintani S, Kusano K, Ii M, Iwakura A, Heyd L, Curry C, Wecker A, Gavin M, Ma H, Kearney M, Silver M, Thorne T, Murohara T, Losordo DW.

Nat. Clin. Pract. Cardiovasc. Med.   Vol. 3(Suppl.)   page： S123-S128   2006

Endothelial progenitor cell transplantation improves the outcome following liver injury in mice. Reviewed

Taniguchi E, Kin M, Torimura T, Nakamura T, Kumemura M, Hanada S, Hisamoto T, Yoshida T, Kawaguchi T, Baba S, Maeyama M, Koga H, Harada M, Kumashiro R, Ueno T, Ikeda H, Imaizumi T, Murohara T, Sata M.

Gastroenterology.   Vol. 130   page： 521-531   2006

Comparison of circulating adiponectin and proinflammatory markers regarding their association with metabolic syndrome in Japanese men. Reviewed

Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Takefuji S, Sugiura K, Kondo T, Murohara T, Toyoshima H.

Arterioscler. Thromb. Vasc. Biol.   Vol. 26   page： 871-876   2006

Effects of intravenous nicorandil before reperfusion for acute myocardial infarction in patients with stress hyperglycemia. Reviewed

Ishii H, Ichimiya S, Kanashiro M, Amano T, Matsubara T, Murohara T.

Diabetes Care.   Vol. 29   page： 202-206   2006

Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men. Reviewed

Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Zhang H, Sugiura K, Kondo T, Murohara T, Toyoshima H.

Atherosclerosis.   Vol. 188   page： 184-189   2006

Platelet P-selectin plays an important role in arterial thrombogenesis by forming large stable platelet-leukocyte aggregates. Reviewed

Yokoyama S, Ikeda H, Haramaki N, Yasukawa H, Murohara T, Imaizumi T.

J. Am. Coll. Cardiol.   Vol. 45   page： 1280-1286   2005

Therapeutic neovascularization using cord blood-derived endothelial progenitor cells for diabetic neuropathy. Reviewed

Naruse K, Hamada Y, Nakashima E, Kato K, Mizubayashi R, Kamiya H, Yuzawa Y, Matsuo S, Murohara T, Matsubara T, Oiso Y, Nakamura J.

Diabetes.   Vol. 54   page： 1823-1828   2005

Therapeutic angiogenesis with intramuscular injection of low dose recombinant granulocyte-colony stimulating factor. Reviewed

Lee M, Aoki M, Kondo T, Okumura K, Komori K, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 25   page： 2535-2541   2005

The impact of a single intravenous administration of nicorandil before reperfusion in patients with ST-segment elevation myocardial infarction. Reviewed

Ishii H, Ichimiya S, Kanashiro M, Amano T, Imai K, Murohara T, Matsubara T.

Circulation.   Vol. 112   page： 1284-1288   2005

CD34+ cells home, proliferate and participate in capillary formation and in combination with CD34- cells enhance tube formation in a 3D matrix. Reviewed

Rookmaaker MB, Verhaar MC, Loomans CJM, Peters E, Murohara T, Staal FJT, van Zonneveld AJ, Koolwijk P, Rabelink TJ, van Hinsbergh VWM.

Arterioscler. Thromb. Vasc. Biol.   Vol. 25   page： 1843-1850   2005

Important role of apoptosis signal-regulating kinase 1 in ischemia-induced angiogenesis. Reviewed

Izumi Y, Kim-Mitsuyama S, Yoshiyama M, Omura T, Shiota M, Matsuzawa A, Yukimura T, Murohara T, Takeya M, Ichijo H, Yoshikawa J, Iwao H.

Arterioscler. Thromb. Vasc. Biol.   Vol. 25   page： 1877-1883   2005

Autologous bone-marrow mononuclear cell implantation improves endothelium-dependent vasodilation in patients with limb ischemia. Reviewed

Higashi Y, Kimura M, Hara K, Noma K, Jituiki D, Nakagawa K, Oshima T, Chayama K, Goto C, Matsubara H, Murohara T, Yoshizumi M.

Circulation.   Vol. 109   page： 1215-1218   2004

Smoking cessation rapidly increases endothelial progenitor cells in peripheral blood in chronic smokers. Reviewed

Kondo T, Hayashi M, Kinoshita K, Kobayashi K, Iino S, Inden Y, Murohara T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 24   page： 1442-1447   2004

Derivation of functional endothelial progenitor cells from human umbilical cord blood mononuclear cells isolated by a novel cell filtration device. Reviewed

Aoki M, Yasutake M, Murohara T.

Stem Cells.   Vol. 22   page： 994-1002   2004

Molecular evaluation of endothelial progenitor cells in patients with ischemic limbs: therapeutic effect by stem cell transplantation. Reviewed

Yamamoto K, Kondo T, Suzuki S, Izawa H, Kobayashi M, Emi N, Komori K, Naoe T, Takamatsu J, Murohara T.

Arterioscler. Throm. Vasc. Biol.   Vol. 24   page： e192-e196   2004

Roles of endogenous monocyte chemoattractant protein-1 in ischemia-induced neovascularization. Reviewed

Niiyama H, Kai H, Yamamoto T, Shimada T, Sasaki K, Murohara T, Egashira K, Imaizumi T.

J. Am. Coll. Cardiol.   Vol. 44   page： 661-666   2004

Augmentation of therapeutic angiogenesis using genetically-modified human endothelial progenitor cells with altered glycogen synthase kinase-3b activity. Reviewed

Choi JH, Hur J, Yoon CH, Kim JH, Lee CS, Youn SW, Oh IY, Skurk C, Murohara T, Park YB, Walsh K, Kim HS.

J. Biol. Chem.   Vol. 279   page： 49430-49438   2004

Angiogenesis and vasculogenesis are impaired in precocious aging Klotho mouse. Reviewed

Shimada T, Takeshita Y, Murohara T, Sasaki K, Egami K, Shintani S, Katsuda Y, Ikeda H, Nabeshima Y, Imaizumi T.

Circulation.   Vol. 110   page： 1148-1155   2004

Inhibition of platelet adherence to mononuclear cells by α-tocopherol: Role of P-selectin. Reviewed

Murohara T, Ikeda H, Otsuka Y, Aoki M, Haramaki N, Katoh A, Takajo Y, Imaizumi T.

Circulation.   Vol. 110   page： 141-148   2004

Hypoxic preconditioning augments efficacy of human endothelial progenitor cells for therapeutic neovascularization. Reviewed

Akita T, Murohara T, Ikeda H, Sasaki K, Shimada T, Egami K, Imaizumi T.

Lab. Invest.   Vol. 83   page： 65-73   2003

Rescue of hypercholesterolemia-related impairment of angiogenesis by oral folate supplementation. Reviewed

Sasaki K, Duan J, Murohara T, Ikeda H, Shintani S, Shimada T, Akita T, Egami K, Imaizumi T.

J. Am. Coll. Cardiol.   Vol. 42   page： 364-372   2003

Role of host angiotensin II type 1 receptor in tumor angiogenesis and growth. Reviewed

Egami K, Murohara T, Shimada T, Sasaki K, Shintani S, Sugaya T, Ishii M, Akagi T, Ikeda H, Matsuishi T, Imaizumi T.

J. Clin. Invest.   Vol. 112   page： 67-75   2003

Evidence for the importance of angiotensin II type 1 receptor in ischemia-induced angiogenesis. Reviewed

Sasaki K, Murohara T, Ikeda H, Sugaya T, Shintani S, Shimada T, Imaizumi T.

J. Clin. Invest.   Vol. 109   page： 603-611   2002

for the Therapeutic Angiogenesis using Cell Transplantation (TACT) Study Investigators. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Reviewed

Tateishi-Yuyama E,* Matsubara H,* Murohara T,* Ikeda U, Shintani S, Masaki H, Amano K, Kishimoto Y, Yoshimoto K, Akashi H, Shimada K, Iwasaka T, Imaizumi T. * equal contribution.

Lancet.   Vol. 360   page： 427-435   2002

Augmentation of postnatal neovascularization with autologous bone marrow transplantation. Reviewed

Shintani S, Murohara T, Ikeda H, Ueno T, Sasaki K, Duan J, Imaizumi T.

Circulation.   Vol. 103   page： 897-903   2001

Intraplatelet tetrahydrobiopterin plays an important role in regulating canine coronary arterial thrombosis by modulating intraplatelet nitric oxide and superoxide generation. Reviewed

Kanaya S, Ikeda H, Haramaki N, Murohara T, Imaizumi T.

Circulation.   Vol. 104   page： 2478-2484   2001

Augmented oxidative stress of platelets in chronic smokers. Mechanisms of impaired platelet-derived nitric oxide bioactivity and augmented platelet aggregability. Reviewed

Takajo Y, Ikeda H, Haramaki N, Murohara T, Imaizumi T.

J. Am. Coll. Cardiol.   Vol. 38   page： 1320-1327   2001

Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Reviewed

Shintani S, Murohara T, Ikeda H, Ueno T, Honma T, Katoh A, Sasaki K, Shimada T, Oike Y, Imaizumi T.

Circulation.   Vol. 103   page： 2776-2779   2001

Platelet-derived nitric oxide and coronary risk factors. Reviewed

Ikeda H, Takajo Y, Murohara T, Ichiki K, Adachi H, Haramaki N, Katoh A, Imaizumi T.

Hypertension.   Vol. 35   page： 904-907   2000

Increased circulating soluble intercellular adhesion molecule-1 in acute myocardial infarction: a possible predictor of reperfusion ventricular arrhythmias. Reviewed

Murohara T, Kamijikkoku S, Honda T.

Crit. Care Med.   Vol. 28   page： 1861-1864   2000

Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. Reviewed

Murohara T, Ikeda H, Duan J, Shintani S, Sasaki K, Eguchi H, Onitsuka I, Matsui K, Imaizumi T.

J. Clin. Invest.   Vol. 28   page： 1861-1864   2000

Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. Reviewed

Duan J, Murohara T, Ikeda H, Katoh A, Shintani S, Sasaki K, Kawata H, Yamamoto N, Imaizumi T.

Circulation.   Vol. 102   page： III370-III376   2000

Age-dependent impairment of angiogenesis. Reviewed

Rivard A, Fabre JE, Silver M, Chen D, Murohara T, Kearney M, Magner M, Asahara T, Isner JM.

Circulation.   Vol. 99   page： 111-120   1999

Adhesive interaction between P-selectin and sialyl Lewis(x) plays an important role in recurrent coronary arterial thrombosis in dogs. Reviewed

Ikeda H, Ueyama T, Murohara T, Yasukawa H, Haramaki N, Eguchi H, Katoh A, Takajo Y, Onitsuka I, Ueno T, Tojo SJ, Imaizumi T.

Arterioscler. Thromb. Vasc. Biol.   Vol. 19   page： 1083-1090   1999

Endothelial injuries of coronary arteries distal to thrombotic sites: role of adhesive interaction between endothelial P-selectin and leukocyte sialyl LewisX. Reviewed

Eguchi H, Ikeda H, Murohara T, Yasukawa H, Haramaki N, Sakisaka S, Imaizumi T.

Circ. Res.   Vol. 84   page： 525-535   1999

Role of endothelial nitric oxide synthase in endothelial cell migration. Reviewed

Murohara T, Witzenbichler B, Spyridopoulos I, Asahara T, Ding B, Sullivan A, Losordo DW, Isner JM.

Arterioscler. Thromb. Vasc. Biol.   Vol. 19   page： 1156-1161   1999

Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Reviewed

Murohara T, Horowitz JR, Silver M, Tsurumi Y, Chen D, Sullivan A, Isner JM.

Circulation.   Vol. 97   page： 99-107   1998

Platelet-derived 12-hydroxyeicosatetraenoic acid plays an important role in mediating canine coronary thrombosis by regulating platelet glycoprotein IIb/IIIa activation. Reviewed

Katoh A, Ikeda H, Murohara T, Haramaki N, Ito H, Imaizumi T.

Circulation.   Vol. 98   page： 2891-2898   1998

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia. Reviewed

Murohara T, Asahara T, Silver M, Bauters C, Masuda H, Kalka C, Kearney M, Chen D, Symes JF, Fishman MC, Huang PL, Isner JM.

J. Clin. Invest.   Vol. 101   page： 2567-2578   1998

Isolation of putative progenitor endothelial cells for angiogenesis. Reviewed

Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM.

Science.   Vol. 275   page： 964-967   1997

Reciprocal relation between VEGF and NO in the regulation of endothelial integrity. Reviewed

Tsurumi Y, Murohara T, Krasinski K, Chen D, Witzenbichler B, Kearney M, Couffinhal T, Isner JM.

Nat. Med.   Vol. 37   page： 879-886   1997

Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium. Reviewed

van der Zee R, Murohara T, Luo Z, Zollmann F, Passeri J, Lekutat C, Isner JM.

Circulation.   Vol. 95   page： 1030-1037   1997

Interactions of nitrovasodilators, atrial natriuretic peptide and endothelium-derived nitric oxide. Reviewed

Murohara T, Kugiyama K, Yasue H.

J. Vasc. Res.   Vol. 33   page： 78-85   1996

Autocrine effects of endothelin-1 on leukocyte-endothelial interaction: stimulation of endothelin B receptor subtype reduces endothelial adhesiveness via a nitric oxide-dependent mechanism. Reviewed

Murohara T, Lefer AM.

Blood.   Vol. 88   page： 3894-3900   1996

Effects of sphingomyelinase and sphingosine on arterial vasomotor regulation. Reviewed

Murohara T, Kugiyama K, Ohgushi M, Sugiyama S, Ohta Y, Yasue H.

J. Lipid Res.   Vol. 37   page： 1601-1608   1996

Effects of angiotensin-converting enzyme inhibitor alacepril in patients with stable effort angina during chronic isosorbide dinitrate treatment. Reviewed

Murohara T, Tayama S, Tabuchi T, Sumida H, Honda T, Hayasaki K, Yasue H.

Am. J. Cardiol.   Vol. 77   page： 1159-1163   1996

Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats. Reviewed

Murohara T, Delyani JA, Albelda SM, Lefer AM.

J. Immunol.   Vol. 156   page： 3550-3557   1996

Lysophosphatidylcholine promotes P-selectin expression in platelets and endothelial cells. Possible involvement of protein kinase C activation and its inhibition by nitric oxide donors. Reviewed

Murohara T, Scalia R, Lefer AM.

Circ. Res.   Vol. 78   page： 780-789   1996

Cardioprotective actions of oligotide, a single stranded polydeoxyribonucleotide complex, in myocardial ischaemia and reperfusion injury. Reviewed

Murohara T, Buerke M, Lefer AM.

Br. J. Pharmacol.   Vol. 117   page： 1000-1008   1996

Cardioprotective effects of a C1 esterase inhibitor in myocardial ischemia and reperfusion. Reviewed

Buerke M, Murohara T, Lefer AM.

Circulation.   Vol. 91   page： 393-402   1995

Cardioprotection by liposome-conjugated sialyl Lewisx-oligosaccharide in myocardial ischaemia and reperfusion injury. Reviewed

Murohara T, Margiotta J, Phillips LM, Paulson JC, DeFrees S, Zalipsky S, Guo LS, Lefer AM.

Cardiovasc. Res.   Vol. 30   page： 965-974   1995

Inhibition of nitric oxide biosynthesis promotes P-selectin expression in platelets. Role of protein kinase C. Reviewed

Murohara T, Parkinson SJ, Waldman SA, Lefer AM.

Arterioscler. Thromb. Vasc. Biol.   Vol. 15   page： 2068-2075   1995

Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion. Reviewed

Buerke M, Murohara T, Skurk C, Nuss C, Tomaselli K, Lefer AM.

Proc. Natl. Acad. Sci. U S A.   Vol. 92   page： 8031-8035   1995

Myocardial and endothelial protection by TMS in ischemia-reperfusion injury. Reviewed

Murohara T, Buerke M, Margiotta J, Ruan F, Igarashi Y, Hakomori S, Lefer AM.

Am. J. Physiol.   Vol. 269   page： H504-H514   1995

Cigarette smoke extract contracts isolated porcine coronary arteries by superoxide anion-mediated degradation of EDRF. Reviewed

Murohara T, Kugiyama K, Ohgushi M, Sugiyama S, Yasue H.

Am. J. Physiol.   Vol. 266   page： H874-H880   1994

Polymorphonuclear leukocyte-induced vasocontraction and endothelial dysfunction. Role of selectins. Reviewed

Murohara T, Buerke M, Lefer AM.

Arterioscler. Thromb. Vasc. Biol.   Vol. 14   page： 1509-1519   1994

LPC in oxidized LDL elicits vasocontraction and inhibits endothelium- dependent relaxation. Reviewed

Murohara T, Kugiyama K, Ohgushi M, Sugiyama S, Ohta Y, Yasue H.

Am. J. Physiol.   Vol. 267   page： H2441-H2449   1994

Age related attenuation of the endothelium dependent relaxation to noradrenaline in isolated pig coronary arteries. Reviewed

Murohara T, Yasue H, Ohgushi M, Sakaino N, Jougasaki M.

Cardiovasc. Res.   Vol. 25   page： 1002-1009   1991

Role of the novel myokine myonectin in regulation of ischemic heart disease

Grant number：17H04175  2017.4 - 2020.3

OUCHI Noriyuki

Role of VEGF165b, an inhibitory vascular endothelial growth factor splice variant, in pulmonary hypertension

Grant number：17K09551  2017.4 - 2020.3

Kondo Takahisa

The potential of omentin as therapeutic agents for cardiovascular disease.

Grant number：17K09572  2017.4 - 2020.3

Shibata Rei

Functions of Nitric Oxide and Endothelium-derived Hyperpolarizing Factor are impaired in Poor Run-off Autogenous Rabbit Arterial Grafts

Grant number：17H04290  2017.4 - 2020.3

KOMORI Kimihiro

脂肪組織由来間葉系前駆細胞を用いた誘導心筋細胞による心筋再生療法の開発

Grant number：17K09574  2017.4 - 2019.3

近藤 和久

Pathophysiological significance of the Klotho-FGF system in myocardial diseases

Grant number：16K09429  2016.4 - 2020.3

Okumura Takahiro

Regulation of pathological vascular remodeling by a novel adipocytokines

Grant number：16K09512  2016.4 - 2019.3

Ohashi Koji

Role of aging regulatory protein WRN in cardiac fibrosis

Grant number：16K09496  2016.4 - 2019.3

Bando Yasuko K.

Evaluation by Frequency Analysis of Surface Electrocardiogram and Rotor Mapping in Left Atrum

Grant number：15K09076  2015.4 - 2018.3

Yasuya Inden

自己脂肪組織由来幹細胞を用いた心血管系再生医療の総合的開発研究

2014.5 - 2017.3

科学研究費補助金  基盤研究(B)

血管再生障害からみた糖尿病性心筋症の基礎解析と新規治療法の開発　　　　　　　　　

2008.5 - 2011.3

科学研究費補助金  基盤研究(A)

室原　豊明

Development of angiogenic cell therapy using iPS cell-derived vascular progenitor cells

2008.4 - 2013.3

Grant-in-Aid for Scientific Research 

磁場と磁気ナノ粒子を用いた細胞シート工学とその再生医療への応用開発研究

2007

科学研究費補助金  萌芽研究，課題番号：19659201

室原　豊明

前駆細胞移植による血管再生療法の分子基盤探索と新規臨床応用に向けた展開研究

2006.5 - 2008.3

科学研究費補助金  基盤研究(B)

バイオペースメーカー細胞の樹立と徐脈性不整脈の細胞治療

2003.4 - 2005.3

科学研究費補助金 

室原　豊明

細胞移植による血管新生療法の改良型開発のための基礎研究

2002 - 2003

科学研究費補助金  基盤研究(B)

室原豊明

内皮前駆細胞移植を応用した虚血心筋の血管新生療法の開発

2000.5 - 2005.3

科学研究費補助金  特定領域研究

室原　豊明

末梢血幹細胞移植を応用した新しい虚血部血管新生療法の開発

2000.5 - 2002.3

科学研究費補助金  基盤研究(B)

室原豊明

コロニー刺激因子を用いた新しい虚血部血管新生療法の開発-内皮前駆細胞動員療法-

2000.5 - 2001.3

科学研究費補助金  特定領域研究

血管新生と血管保護療法の開発に関する研究

2000 - 2004

科学研究費補助金  厚生労働省厚生労働科学研究費補助金（ヒトゲノム・再生医療等研究事業）

ヒト臍帯血からの内皮前駆細胞単離および分化誘導と血管新生療法への応用

1999.5 - 2001.3

科学研究費補助金  基盤研究(B)

室原豊明

自己骨髄単核細胞移植による心筋梗塞後血管新生療法の実験的試み

1999.5 - 2000.3

科学研究費補助金  特定領域研究

高脂血症における組織虚血後の血管新生に関する研究

1998.5 - 1999.3

科学研究費補助金  科学研究費補助金　奨励研究 A