2022/10/26 更新

写真a

ヤツヤ ヒロシ
八谷 寛
YATSUYA Hiroshi
所属
大学院医学系研究科 総合医学専攻 社会生命科学 教授
大学院担当
大学院医学系研究科
学部担当
医学部 医学科
職名
教授
連絡先
メールアドレス
外部リンク

学位 1

  1. 医学博士 ( 2003年1月   名古屋大学 ) 

研究キーワード 11

  1. 予防

  2. 公衆衛生

  3. 糖尿病

  4. 循環器疾患

  5. 肥満

  6. 生活習慣病

  7. 疫学

  8. 心血管疾患

  9. コホート研究

  10. 生活習慣病

  11. 肥満

研究分野 5

  1. ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含まない

  2. ライフサイエンス / 医療管理学、医療系社会学

  3. ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含まない

  4. ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含む

  5. ライフサイエンス / 衛生学、公衆衛生学分野:実験系を含む

現在の研究課題とSDGs 1

  1. 生活習慣病の疫学研究

経歴 10

  1. 名古屋大学大学院医学系研究科   国際保健医療学・公衆衛生学   教授

    2020年10月 - 現在

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    国名:日本国

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  2. 藤田保健衛生大学医学部(藤田医科大学)   公衆衛生学   教授

    2012年7月 - 2021年3月

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    国名:日本国

  3. 藤田保健衛生大学   医学部   教授

    2012年7月 - 2021年3月

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  4. 名古屋大学 大学院医学系研究科   国際保健医療学・公衆衛生学分野   准教授

    2011年4月 - 2012年6月

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    国名:日本国

  5. 名古屋大学 大学院医学系研究科   公衆衛生学分野   准教授

    2010年9月 - 2011年3月

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    国名:日本国

  6. 米国ミネソタ大学公衆衛生大学院疫学地域保健部門 Visiting Associate Professor

    2008年9月 - 2010年8月

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    国名:アメリカ合衆国

  7. 名古屋大学大学院医学系研究科准教授

    2007年4月 - 2010年8月

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    国名:日本国

  8. 名古屋大学大学院医学系研究科助教授

    2004年6月 - 2007年3月

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    国名:日本国

  9. 名古屋大学大学院医学系研究科助手

    2000年5月 - 2004年6月

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    国名:日本国

  10. 半田市立半田病院

    1996年5月 - 1997年3月

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    国名:日本国

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学歴 2

  1. 名古屋大学   医学研究科   社会医学

    1997年4月 - 2000年4月

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    国名: 日本国

  2. 名古屋大学   医学部   医学科

    - 1996年3月

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    国名: 日本国

所属学協会 19

  1. 日本疫学会

  2. 日本公衆衛生学会

  3. 日本産業衛生学会

  4. 日本循環器病予防学会

  5. 日本学校保健学会

  6. 東海公衆衛生学会

  7. 日本社会医学会

  8. 日本肥満学会

  9. 日本動脈硬化学会

  10. 日本循環器学会

  11. 国際疫学会

  12. American Heart Association

  13. 東海公衆衛生学会

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  14. 日本肥満学会

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  15. 日本産業衛生学会

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  16. 日本循環器病予防学会

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  17. 日本学校保健学会

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  18. 日本動脈硬化学会

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  19. 日本公衆衛生学会

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委員歴 23

  1. 日本学術会議   連携会員  

    2014年10月 - 現在   

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    団体区分:政府

    第23期生活習慣病対策分科会幹事(2014-2017)
    第24期生活習慣病対策分科会委員長(2017-2020)
    第25期生活習慣病対策分科会委員長(2020-2023)

  2. 内閣府食品安全委員会   ビスフェノールAの健康影響に関する調査事業検討会委員  

    2019年8月 - 2020年3月   

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    団体区分:政府

  3. 岩倉市健幸づくり推進委員会   委員長  

    2019年5月 - 現在   

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    団体区分:自治体

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  4. 東海公衆衛生学会   理事  

    2018年4月 - 現在   

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    団体区分:学協会

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  5. 日本学術会議 生活習慣病対策分科会   委員長  

    2018年2月 - 現在   

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    団体区分:政府

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  6. 愛知県医師会   地域医療政策研究機構委員会・委員  

    2018年1月 - 現在   

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    団体区分:その他

  7. 日本疫学会 広報委員会   委員  

    2018年1月 - 現在   

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    団体区分:学協会

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  8. Journal of Epidemiology   編集委員  

    2017年1月 - 現在   

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    団体区分:学協会

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  9. Journal of Epidemiology   Associate Editor  

    2017年1月 - 現在   

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    団体区分:学協会

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  10. Fujita Medical Journal   編集委員長  

    2015年2月 - 現在   

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    団体区分:学協会

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  11. Fujita Medical Journal   Editor-in-Chief  

    2015年2月 - 現在   

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    団体区分:学協会

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  12. 日本学術会議   連携会員  

    2014年10月 - 現在   

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    団体区分:政府

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  13. Science Council of Japan   member  

    2014年10月 - 現在   

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    団体区分:政府

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  14. 東海公衆衛生雑誌   編集委員  

    2014年10月 - 2017年7月   

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    団体区分:学協会

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  15. 日本公衆衛生学会   評議員  

    2014年7月 - 現在   

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    団体区分:学協会

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  16. 日本疫学会   評議員  

    2013年1月 - 現在   

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    団体区分:学協会

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  17. 日本産業衛生学会   代議員  

    2012年11月 - 現在   

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    団体区分:学協会

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  18. Journal of Atherosclerosis and Thrombosis   編集委員  

    2012年10月 - 現在   

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    団体区分:学協会

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  19. Journal of Atherosclerosis and Thrombosis   Editor  

    2012年10月 - 現在   

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    団体区分:学協会

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  20. 東海公衆衛生学会   評議員  

    2012年4月 - 2018年3月   

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    団体区分:学協会

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  21. 日本循環器病予防学会(循環器管理研究協議会)   評議員  

    2010年5月 - 現在   

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    団体区分:学協会

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  22. 農林水産省   「食事バランスガイド」を活用した「日本型食生活」の効果を科学的に検証 する事業、検討会委員  

    2008年4月 - 2009年3月   

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    団体区分:政府

  23. 国立研究開発法人 国立長寿医療研究センター   倫理・利益相反委員会 委員  

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    団体区分:その他

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受賞 4

  1. 日本疫学会奨励賞

    2007年1月   日本疫学会  

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    受賞国:日本国

  2. 日本社会医学会奨励賞

    2007年7月   日本社会医学会  

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    受賞国:日本国

  3. Journal of Epidemiology ベストレビューアー賞

    2016年1月   日本疫学会  

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    受賞区分:学会誌・学術雑誌による顕彰  受賞国:日本国

  4. Journal of Epidemiology ベストレビューアー賞

    2012年1月   日本疫学会  

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    受賞区分:学会誌・学術雑誌による顕彰  受賞国:日本国

 

論文 297

  1. Long-term variability and change trend of systolic blood pressure and risk of type 2 diabetes mellitus in middle-aged Japanese individuals: findings of the Aichi Workers' Cohort Study. 査読有り 国際共著 国際誌

    Song Z, He Y, Chiang C, Al-Shoaibi AAA, Saif-Ur-Rahman KM, Mamun MR, Aoyama A, Hirakawa Y, Matsunaga M, Ota A, Tamakoshi K, Li Y, Yatsuya H

    Hypertension research : official journal of the Japanese Society of Hypertension     2022年8月

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    担当区分:最終著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Hypertension Research  

    Studies have reported that short-term blood pressure (BP) variability (BPV) is associated with type 2 diabetes mellitus (T2DM) incidence, but the association with long-term BPV remains unclear. The present study investigated the associations of long-term BPV as well as the time trend of BP changes over time with the incidence of T2DM. This study followed a cohort of 3017 Japanese individuals (2446 male, 571 female) aged 36–65 years from 2007 through March 31, 2019. The root-mean-square error (RMSE) and the slope of systolic BP (SBP) change regressed on year were calculated individually using SBP values obtained from 2003 to baseline (2007). A multivariable Cox proportional hazard model was applied to estimate hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for tertiles of SBP RMSE and continuous SBP slopes adjusted for age, sex, smoking status, regular exercise, sodium intake, family history of diabetes, sleep disorder, body mass index (BMI), SBP, and fasting blood glucose (FBG) at baseline, and BMI slope from 2003 to 2007. The highest RMSE tertile compared to the lowest was associated with a significantly higher incidence of T2DM after adjusting for covariates (HR: 1.79, 95% CI: 1.15, 2.78). The slope was also significantly associated with T2DM incidence until baseline SBP and FBG were adjusted (HR: 1.03, 95% CI: 0.99, 1.07). In conclusion, long-term SBP variability was significantly associated with an increased incidence of T2DM independent of baseline age, sex, BMI, SBP, FBG, lifestyle factors and BMI slope from 2003 until baseline.

    DOI: 10.1038/s41440-022-00993-2

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    その他リンク: https://www.nature.com/articles/s41440-022-00993-2

  2. Super-additive associations between parity and education level on mortality from cardiovascular disease and other causes: the Japan Collaborative Cohort Study 査読有り 国際誌

    Yasukawa S., Eguchi E., Tamakoshi A., Iso H., Tamakoshi A., Iso H., Mori M., Kaneko Y., Tsuji I., Nakamura Y., Yamagishi K., Mikami H., Kurosawa M., Hoshiyama Y., Tanabe N., Tamakoshi K., Wakai K., Ando M., Suzuki K., Hashimoto S., Yatsuya H., Kikuchi S., Wada Y., Okabayashi S., Ozasa K., Mikami K., Sakata K., Kurozawa Y., Fujino Y.

    BMC Women's Health   22 巻 ( 1 )   2022年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Women's Health  

    Background: While women’s parity status and education level have independent associations with cardiovascular and other diseases, no studies have evaluated the additive interaction of these two factors. Therefore, we examined the additive interaction between parity and education level on mortality from stroke, coronary heart disease, total cardiovascular disease, cancer, non-cardiovascular disease, and non-cancer causes, and all causes in Japanese women. Methods: This study followed 41,242 women aged 40–79 years without a history of cardiovascular disease or cancer from 1988 to 1990 until 2009. Baseline parity and education level were classified into four categories, with highly educated parous women as the reference group. Cox proportional hazards regression analyses were performed to calculate the risk of mortality. We also assessed the additive interactions between parity and education level on mortality from cardiovascular disease and other causes using the relative excess risk due to interaction obtained using Cox models. Results: During the median follow-up period of 19.1 years, we identified 6299 deaths. In a multivariable model adjusted for cardiovascular disease and other disease risk factors, nulliparous women with low education levels had increased multivariable-adjusted hazard ratios of 1.67 (95% confidence interval [CI] 1.13, 2.47) for stroke, 1.98 (95% CI 1.15, 3.39) for coronary heart disease, 1.71 (95% CI 1.34,2.18) for total cardiovascular disease, 1.69 (95% CI 1.33, 2.14) for non-cardiovascular and non-cancer, and 1.51 (95% CI 1.30, 1.75) for all-cause mortality when compared with highly educated parous women. Moreover, we observed significant additive interactions between parity and education level on total cardiovascular disease mortality (P = 0.04), non-cardiovascular disease and non-cancer mortality (P = 0.01), and all-cause mortality (P = 0.005). Conclusions: Nulliparity and low education levels are super-additively associated with total cardiovascular disease, non-cardiovascular and non-cancer, and all-cause mortality risks, suggesting that nulliparous women with low education levels need specific support for preventing mortality related to cardiovascular and other diseases.

    DOI: 10.1186/s12905-022-01805-y

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  3. The association of public trust with the utilization of digital contact tracing for COVID-19 in Japan. 査読有り 国際誌

    He Y, Yatsuya H, Ota A, Tabuchi T

    Public health in practice (Oxford, England)   4 巻   頁: 100279 - 100279   2022年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Public Health in Practice  

    Objectives: To examin whether public trust was associated with the utilization of COVID-19 Contact Confirming Application (COCOA) in those who self-reported a history of COVID-19. Study design: Cross-sectional study. Methods: Data were obtained from the Japan Society and New Tobacco Internet Survey, a nationwide online survey conducted from February to March 2021, which also assessed items related to COVID-19 and public trust. We included 453 participants with a history of COVID-19. Participants' reports of their general trust in the national government and the related policies, attitudes toward COVID-19 vaccination, and the adherence to the preventive measures against SARS-CoV-2 spread were compared between COCOA users and non-users controlling for age, sex, and socioeconomic statuses by analysis of covariance. Mediation analysis was conducted to examine whether public trust mediates the associations of certain participants’ characteristics with COCOA utilization. Results: Seventy-six percent (344/453) reported the COCOA utilization. Compared to non-users, the users were younger, more likely to be men and had a tendency to have higher education. They were more willing to get COVID-19 vaccination, adherent to public health measures against the spread of the SARS-Cov-2, and more likely to express trust in government in general and policies related to COVID-19 independent of age, sex, and the socioeconomic status. Trust in government did not mediate the associations of age and education with COCOA utilization. Conclusions: The utilization of digital contact tracing technology for the health of public during pandemic was related to the degree of trust in the government in Japan.

    DOI: 10.1016/j.puhip.2022.100279

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  4. Impact of Body Mass Index on Obesity-Related Cancer and Cardiovascular Disease Mortality; The Japan Collaborative Cohort Study. 査読有り 国際誌

    Matsunaga M, Yatsuya H, Iso H, Li Y, Yamagishi K, Tanabe N, Wada Y, Ota A, Tamakoshi K, Tamakoshi A

    Journal of atherosclerosis and thrombosis   29 巻 ( 10 ) 頁: 1547 - 1562   2022年10月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Atherosclerosis and Thrombosis  

    Aim: We aimed to examine the association of obesity-related cancer and cardiovascular disease (CVD) with body mass index (BMI) and the estimated population attributable fraction in lean Asians. Methods: We studied 102,535 participants aged 40–79 years without histories of cancer or CVD at baseline between 1988 and 2009. The cause-specific hazard ratios (csHRs) of BMI categories (<18.5, 18.5–20.9, 21.0– 22.9 [reference], 23.0–24.9, 25.0–27.4, and ≥ 27.5 kg/m2) were estimated for each endpoint. The events considered were mortalities from obesity-related cancer (esophageal, colorectal, liver, pancreatic, kidney, female breast, and endometrial cancer) and those from CVD (coronary heart disease and stroke). Population attributable fractions (PAFs) were calculated for these endpoints. Results: During a 19.2-year median follow-up, 2906 died from obesity-related cancer and 4532 died from CVD. The multivariable-adjusted csHRs (95% confidence interval) of higher BMI categories (25–27.4 and ≥ 27.5 kg/m2) for obesity-related cancer mortality were 0.93 (0.78, 1.10) and 1.18 (0.92, 1.50) in men and 1.25 (1.04, 1.50) and 1.48 (1.19, 1.84) in women, respectively. The corresponding csHRs for CVD mortality were 1.27 (1.10, 1.46) and 1.59 (1.30, 1.95) in men and 1.10 (0.95, 1.28) and 1.44 (1.21, 1.72) in women, respectively. The PAF of a BMI ≥ 25 kg/m2 for obesity-related cancer was −0.2% in men and 6.7% in women and that for CVD was 5.0% in men and 4.5% in women. Conclusion: A BMI ≥ 25 kg/m2 is associated with an increased risk of obesity-related cancer in women and CVD in both sexes.

    DOI: 10.5551/jat.63143

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  5. Increased serum anti-CYP2E1 IgG autoantibody levels may be involved in the pathogenesis of occupational trichloroethylene hypersensitivity syndrome: a case-control study. 査読有り 国際誌

    Nakajima T, Wang H, Yuan Y, Ito Y, Naito H, Kawamoto Y, Takeda K, Sakai K, Zhao N, Li H, Qiu X, Xia L, Chen J, Wu Q, Li L, Huang H, Yanagiba Y, Yatsuya H, Kamijima M

    Archives of toxicology   96 巻 ( 10 ) 頁: 2785 - 2797   2022年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Archives of Toxicology  

    Occupational exposure to trichloroethylene (TCE) causes a systemic skin disorder with hepatitis known as TCE hypersensitivity syndrome (TCE-HS). Human Leukocyte Antigen (HLA)-B*13:01 is its susceptibility factor; however, the immunological pathogenesis of TCE-HS remains unknown. We herein examined the hypothesis that autoantibodies to CYP2E1 are primarily involved in TCE-HS. A case–control study of 80 TCE-HS patients, 186 TCE-tolerant controls (TCE-TC), and 71 TCE-nonexposed controls (TCE-nonEC) was conducted to measure their serum anti-CYP2E1 antibody (IgG) levels. The effects of TCE exposure indices, such as 8-h time-weighted-average (TWA) airborne concentrations, urinary metabolite concentrations, and TCE usage duration; sex; smoking and drinking habits; and alanine aminotransferase (ALT) levels on the antibody levels were also analyzed in the two control groups. There were significant differences in anti-CYP2E1 antibody levels among the three groups: TCE-TC > TCE-HS patients > TCE-nonEC. Antibody levels were not different between HLA-B*13:01 carriers and noncarriers in TCE-HS patients and TCE-TC. The serum CYP2E1 measurement suggested increased immunocomplex levels only in patients with TCE-HS. Multiple regression analysis for the two control groups showed that the antibody levels were significantly higher by the TCE exposure. Women had higher antibody levels than men; however, smoking, drinking, and ALT levels did not affect the anti-CYP2E1 antibody levels. Anti-CYP2E1 antibodies were elevated at concentrations lower than the TWA concentration of 2.5 ppm for TCE exposure. Since HLA-B*13:01 polymorphism was not involved in the autoantibody levels, the possible mechanism underlying the pathogenesis of TCE-HS is that TCE exposure induces anti-CYP2E1 autoantibody production, and HLA-B*13:01 is involved in the development of TCE-HS.

    DOI: 10.1007/s00204-022-03326-x

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  6. Association between irregular daily routine and risk of incident stroke and coronary heart disease in a large Japanese population. 査読有り 国際誌

    Yoshizaki T, Ishihara J, Kotemori A, Kokubo Y, Saito I, Yatsuya H, Yamagishi K, Sawada N, Iwasaki M, Iso H, Tsugane S, JPHC Study Group.

    Scientific reports   12 巻 ( 1 ) 頁: 15750 - 15750   2022年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Scientific Reports  

    Circadian misalignments have been linked to adverse cardiometabolic outcomes. However, the association between irregular daily routine and the risk of cardiovascular disease (CVD) remains unknown. We examined this association in a prospective study in Japan. The study included 78,115 Japanese participants aged 45–74 years. The self-reported daily routine was evaluated using the question, ‘Is your daily routine or activity schedule regular?’ The response (yes/no) was obtained as a binary variable. Cox proportional hazard regression analysis was used to estimate the hazard ratios and 95% confidence intervals for the association between an irregular daily routine and CVD incidence risk. Among the participants, 23.7% reported an irregular daily routine. During the mean follow-up period of 13.3 years, we observed 4641 CVD events. An irregular daily routine was significantly associated with increased risks of CVD and total stroke in women, but not in men. This positive association between an irregular daily routine and the risk of CVD was weak in the high vegetable and fruit consuming population. An irregular daily routine is positively associated with the risk of incident CVD, especially in women. These associations may be weak in populations that consume a diet rich in vegetables and fruits.

    DOI: 10.1038/s41598-022-20019-8

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  7. Diabetes management in people living with dementia in Japan: a qualitative exploration. 査読有り 国際誌

    Km SU, Hirano Y, Hirakawa Y, Yatsuya H

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society   22 巻 ( 5 ) 頁: 728 - 735   2022年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Psychogeriatrics  

    Background: Dementia and diabetes are highly prevalent among the older society in Japan. People living with dementia (PLWD) often face hurdles in managing diabetes. This study explored the perspectives of healthcare providers in Japan regarding diabetes management in PLWD. Methods: We conducted a qualitative study using in-depth interviews as a data collection method. A total of 15 physicians and nurses were interviewed. A qualitative content analysis of the codes was performed to generate the themes. Results: The major themes focused on the management of medications/therapeutic regimen, difficulties of continuing health care, emotional aspects of PLWD for adherence to lifestyle modification, and varying direction and degree of family support for diabetes care. Conclusion: PLWD in Japan face challenges in medication management, food restriction, and lifestyle modification. Policies to engage home visit care workers in medication management, consideration of the emotional aspect of PLWD, and utilisation of social support might help in the proper management of diabetes in PLWD.

    DOI: 10.1111/psyg.12876

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  8. Secondhand smoke and the risk of incident cardiovascular disease among never-smoking women. 査読有り 国際誌

    Kobayashi Y, Yamagishi K, Muraki I, Kokubo Y, Saito I, Yatsuya H, Iso H, Tsugane S, Sawada N, JPHC Study Group.

    Preventive medicine   162 巻   頁: 107145 - 107145   2022年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ypmed.2022.107145

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  9. Including Measures of Chronic Kidney Disease to Improve Cardiovascular Risk Prediction by SCORE2 and SCORE2-OP. 査読有り 国際共著 国際誌

    Matsushita K, Kaptoge S, Hageman SH, Sang Y, Ballew SH, Grams ME, Surapaneni A, Sun L, Arnlov J, Bozic M, Brenner H, Brunskill NJ, Chang AR, Chinnadurai R, Cirillo M, Correa A, Ebert N, Eckardt KU, Gansevoort RT, Gutierrez O, Hadaegh F, He J, Hwang SJ, Jafar TH, Jassal SK, Kayama T, Kovesdy CP, Landman GW, Levey AS, Lloyd-Jones DM, Major RW, Miura K, Muntner P, Nadkarni GN, Nowak C, Ohkubo T, Pena MJ, Polkinghorne KR, Sairenchi T, Schaeffner E, Schneider MP, Shalev V, Shlipak MG, Solbu MD, Stempniewicz N, Tollitt J, Valdivielso JM, van der Leeuw J, Wang AYM, Wen CP, Woodward M, Yamagishi K, Yatsuya H, Zhang L, Dorresteijn JA, Di Angelantonio E, Visseren FL, Pennells L, Coresh J, Chronic Kidney Disease Prognosis Consortium.

    European journal of preventive cardiology     2022年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/eurjpc/zwac176

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  10. A comparative study of the work-family conflicts prevalence, their sociodemographic, family, and work attributes, and their relation to the self-reported health status in Japanese and Egyptian civil workers. 査読有り 国際共著 国際誌

    Latief OKAE, Eshak ES, Mahfouz EM, Iso H, Yatsuya H, Sameh EM, Ghazawy ER, Baba S, Emam SA, El-Khateeb AS, Hassan EE

    BMC public health   22 巻 ( 1 ) 頁: 1490   2022年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Public Health  

    Background: Cross-cultural studies studying work-family conflicts (W_F_Cs) are scarce. We compared the prevalence of W_F_Cs, factors correlated with them, and their association with self-rated health between Japan and Egypt. Methods: Among 4862 Japanese and 3111 Egyptian civil workers recruited by a convenience sample in 2018/2019 and reported self-rated health status, we assessed the W_F_Cs by the Midlife Development in the US (MIDUS) and attributed them to sociodemographic, family, and work variables. We also evaluated the W_F_Cs’ gender- and country-specific associations with self-rated health by logistic regression analyses. Results: W_F_Cs were more prevalent in Egyptian than in Japanese women (23.7% vs. 18.2%) and men (19.1% vs. 10.5%), while poor self-rated health was more prevalent in Japanese than Egyptians (19.3% and 17.3% vs. 16.9% and 5.5%). Longer working hours, shift work, and overtime work were positively associated with stronger work-to-family conflict (WFC). Whereas being single was inversely associated with stronger family-to-work conflict (FWC). Living with children, fathers, or alone in Japan while education in Egypt was associated with these conflicts. The OR (95% CI) for poor self-reported health among those with the strong, in reference to weak total W_F_Cs, was 4.28 (2.91–6.30) and 6.01 (4.50–8.01) in Japanese women and men and was 2.46 (1.75–3.47) and 3.11 (1.67–5.80) in Egyptian women and men. Conclusions: Japanese and Egyptian civil workers have different prevalence and correlated factors of W_F_Cs and self-rated health. W_F_Cs were associated in a dose–response pattern with poor-self-rated health of civil workers in both countries.

    DOI: 10.1186/s12889-022-13924-0

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  11. [Impact of the COVID-19 pandemic on national and prefectural health and nutrition examination surveys: A report by the Monitoring Report Committee of the Japanese Society of Public Health]. 査読有り

    Kubo A, Kuno K, Maruyama K, Tsukinoki R, Noda H, Egawa K, Shibuya I, Sei M, Chihara M, Nishina K, Yatsuya H

    [Nihon koshu eisei zasshi] Japanese journal of public health   69 巻 ( 8 ) 頁: 586 - 594   2022年8月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:日本公衆衛生学会  

    <p><b>目的</b> 新型コロナウイルス感染症の蔓延により2020年度および2021年度の国民健康・栄養調査が中止され,都道府県の調査も中止または延期が予想されたため,日本公衆衛生学会公衆衛生モニタリング・レポート委員会生活習慣病・公衆栄養グループでは都道府県民健康・栄養調査の実施状況を調査し,公衆衛生施策立案のために必要なデータ収集の現状と課題を検討した。</p><p><b>方法</b> 47都道府県の調査担当者を対象に,郵送もしくは電子媒体による自記式質問紙調査を実施した。</p><p><b>結果</b> 47都道府県(回収率100%)から回答が得られた。健康・栄養調査を実施しているのは44自治体(93.6%)であった。新型コロナウイルス感染症の影響から2020年度調査予定の18自治体のうち「予定通りの内容で実施した」は2(11.1%)「中止した」は16(88.9%)であった。2021年度調査予定の31自治体のうち「予定通りの内容で実施した」は4(12.9%)「内容を一部変更して実施した」は5(16.1%)「中止した」は22(71.0%)であった。今後の調査方法について,身体状況調査実施の32自治体のうち「変更する予定はない」は6(18.8%)「未定」は18(56.3%)であった。栄養摂取状況調査実施の40自治体のうち「変更する予定はない」は12(30.0%)「未定」は19(47.5%)であった。2か年とも調査を中止した13自治体の各種計画評価は「各種計画期間を延長する」8(61.5%)「その他」7(53.8%)であった。2か年に調査を中止または延期した38自治体のうち,各種計画評価に関する問題点は「調査法の変更に伴う経年評価が不可能になる」「コロナ禍でのライフスタイル変化の影響が想定される」「評価に影響はないが評価期間が短縮となる」「国民健康・栄養調査中止により全国比較が不可能である」等があげられた。</p><p><b>結論</b> 都道府県健康増進計画等の評価のため,ほとんどの自治体が都道府県民健康・栄養調査を実施していた。また,全国比較ができるよう国民健康・栄養調査と同じ方式で実施する自治体が多かった。新型コロナウイルス感染症の影響により,国民健康・栄養調査と同様に調査を中止する都道府県が多く,今後の調査も未定と回答する自治体が多かった。</p>

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  12. Combined Exoscopic and Endoscopic Two-Step Keyhole Approach for Intracranial Meningiomas. 査読有り 国際誌

    Watanabe T, Iwami K, Kishida Y, Nagatani T, Yatsuya H, Miyachi S

    Current oncology (Toronto, Ont.)   29 巻 ( 8 ) 頁: 5370 - 5382   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Current Oncology  

    The advantages of neuroendoscopic surgery are the wide viewing angle and the freedom of an axis of view with minimal surgical trauma. With the advent of the exoscope, which has similar advantages to endoscopy, such as a small body and ergonomically superior heads-up surgery, it has become possible to add a field of view that is similar to that of microsurgery to endoscopic surgery. By taking advantage of the features of these scopes, we report the usefulness of the minimally invasive combined exoscopic and endoscopic two-step keyhole approach (EEKA) for various types of meningiomas. We reviewed data from 34 consecutive cases of EEKA for various types of intracranial meningiomas compared with that of conventional microsurgery. All of the tumors were resected as planned without severe complications. Significantly better outcome data were obtained in terms of the blood loss and the surgical time in the EEKA group, in addition to the craniotomy size. The well-illuminated fine vision in the deep corners by the endoscope enabled radical resection of the tumors with minimum burden on the patients. This technique has the potential for minimally invasive surgery in intracranial meningioma patients, including the older population.

    DOI: 10.3390/curroncol29080426

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  13. Dietary Patterns Derived from Reduced Rank Regression Are Associated with the 5-Year Occurrence of Metabolic Syndrome: Aichi Workers' Cohort Study. 査読有り 国際誌

    Li Y, Yatsuya H, Wang C, Uemura M, Matsunaga M, He Y, Khine M, Ota A

    Nutrients   14 巻 ( 15 ) 頁: 3019 - 3019   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nutrients  

    The aim of the present study was to derive dietary patterns to explain variation in a set of nutrient intakes or in the measurements of waist circumference (WC) and fasting blood glucose (FBG) using reduced rank regression (RRR) and to prospectively investigate these patterns in relation to the risk of developing metabolic syndrome (MetS) and its components during the follow-up. The study participants were comprised of 2944 government employees aged 30–59 years without MetS. RRR was applied with 38 food groups as predictors and with two sets of response variables. The first set included intake of putatively beneficial nutrients, and the first factor retained was named the Healthy Dietary Pattern (HDP). The second one included baseline WC and FBG, and the first factor was named the Unhealthy Dietary Pattern (UHDP). Multivariable Cox proportional hazard model was used to estimate hazard ratio and 95% confidence intervals with adjustments for age, sex, total energy consumption and other potential confounders. During the 5-year median follow-up, we ascertained 374 cases of MetS. The HDP score was inversely associated with the incidence of MetS (p-trend = 0.009) and hypertension (p-trend = 0.002) and marginally significantly associated with elevated triglyceride and decreased high-density lipoprotein cholesterol (p-trend = 0.08). The UHDP score was linearly positively associated with the incidence of MetS and all its components (all p-trend < 0.05). Both the HDP and UHDP predicted the development of MetS and its components.

    DOI: 10.3390/nu14153019

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  14. Influence of the COVID-19 pandemic on regular clinic visits and medication prescriptions among people with diabetes: Retrospective cohort analysis of health care claims. 査読有り 国際誌

    Maeda T, Nishi T, Harada M, Tanno K, Nishiya N, Asayama K, Okuda N, Sugiyama D, Yatsuya H, Okayama A, Arima H

    Medicine   101 巻 ( 29 ) 頁: e29458   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Medicine (United States)  

    The aim of this study was to investigate the effect of the COVID-19 pandemic on regular clinic visits among people with diabetes and to elucidate the factors related to visit patterns among these patients during the pandemic. This was a longitudinal study using anonymized insurance claims data from the Joint Health Insurance Society in Tokyo from October 2017 to September 2020. First, we identified patients with diabetes who were fully enrolled in the health plan from fiscal year 2017 until September 2020 and who were regularly receiving glucose-lowering medications (every 1-3 months) from October 2017 to September 2018. We divided follow-up into the pre-pandemic period (October 2018 to March 2020) and the pandemic period (April 2020 to September 2020). A multilevel logistic regression model was used to determine the risks of delayed clinic visits/medication prescriptions (i.e., >3 months after a previous visit/prescription) during the pandemic period. We identified 1118 study participants. The number of delayed clinic visits/medication prescriptions during the pre-pandemic and pandemic periods was 188/3354 (5.6%) and 125/1118 (11.2%), respectively. There was a significant increase in delayed clinic visits during the pandemic (adjusted odds ratio 3.68 (95% confidence interval 2.24 to 6.04, P <.001), even after controlling for confounding factors. We also found a significant interaction between sex and delayed visits; women had significantly fewer clinic visits during the COVID-19 pandemic than men. We clarified the relationship of the COVID-19 pandemic with delays in regular clinic visits and medication prescriptions among people with diabetes. The response to the COVID-19 pandemic differed between men and women.

    DOI: 10.1097/MD.0000000000029458

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  15. Association of Low-Density Lipoprotein Cholesterol with Risk of Coronary Heart Disease and Stroke among Middle-Aged Japanese Workers: An Analysis using Inverse Probability Weighting. 査読有り 国際共著 国際誌

    Al-Shoaibi AAA, Li Y, Song Z, Chiang C, Hirakawa Y, Saif-Ur-Rahman KM, Shimoda M, Nakano Y, Matsunaga M, Aoyama A, Tamakoshi K, Ota A, Yatsuya H

    Journal of atherosclerosis and thrombosis   advpub 巻 ( 0 )   2022年7月

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    担当区分:最終著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:一般社団法人 日本動脈硬化学会  

    DOI: 10.5551/jat.63519

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  16. Endoscopic sphincterotomy and endoscopic biliary stenting do not affect the sensitivity of transpapillary forceps biopsy for the diagnosis of bile duct adenocarcinoma. 査読有り 国際誌

    Aoki T, Ohno E, Ishikawa T, Mizutani Y, Iida T, Yamao K, Yamamura T, Furukawa K, Nakamura M, Honda T, Ishigami M, Yatsuya H, Kawashima H

    BMC gastroenterology   22 巻 ( 1 ) 頁: 329   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Gastroenterology  

    Background: The pathological evaluation of tissues with cholangitis is considered difficult, which can often occur after endoscopic sphincterotomy (EST) and endoscopic biliary stenting (EBS). This study aimed to evaluate the influence of a history of EST and EBS on the sensitivity of transpapillary forceps bile duct biopsy (TB) for bile duct adenocarcinoma. Methods: This retrospective study included consecutive cases of bile duct adenocarcinoma in which TB was performed before July 2020 until the number exceeded that required to support statistical and noninferiority analyses of the sensitivity of TB between patients with and without each variable. The incidence of postprocedural adverse events related to each factor was also investigated. Results: Overall, 280 samples were required in each group, and 437 subjects (792 samples) were included. The sensitivity of TB was 63.6% for the subjects and 59.6% for the biopsy samples. For the biopsy samples, the sensitivity did not differ significantly between samples from patients with and without a history of EST (59.1% vs. 58.9%, P = 0.952) and EBS (62.1% vs. 55.4%, P = 0.065). The sensitivity was significantly higher for samples from patients with jaundice (67.9% vs. 57.0%, P = 0.008). There were significantly fewer procedure-related adverse events in patients with a history of EST (10.8% vs. 19.0%, P = 0.017) and EBS (12.0% vs. 21.7%, P = 0.005). Conclusions: A history of EST or EBS did not influence sensitivity of TB but significantly decreased the incidence of adverse events. To safely and reliably perform TB to diagnose bile duct adenocarcinoma, planning, including for EST and EBS, is necessary.

    DOI: 10.1186/s12876-022-02402-x

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  17. 新型コロナウイルス感染拡大が日本の医療・介護・福祉の現場にもたらした初期段階の影響に関する質的研究 査読有り

    平野 有希子, 平川 仁尚, 江 啓発, 八谷 寛

    東海公衆衛生雑誌   10 巻 ( 1 ) 頁: 85 - 94   2022年7月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:東海公衆衛生学会  

    <p><b>目的</b> 新型コロナウイルス (SARS-COV-2) の感染拡大初期に医療・介護・福祉の現場で起きた課題の構造を整理することは, 今後直面する可能性がある新たな新興感染症への対策策定の第一歩として有用と考えられる。本研究では, 2020年4~5月頃の新型コロナウイルス感染拡大の初期段階における地域の医療・介護・福祉の現場の課題とその構造を実務者の言説の質的分析を通して明らかにすることを目的とした。</p><p><b>方法</b> 医療・介護・福祉従事者27名を対象に2020年4月から5月にオンラインインタビュー調査を実施した。インタビューガイドを用いた半構造化インタビューとし, 自由回答形式で行った。録画したインタビュー内容から逐語録を作成し, テキストデータを質的内容分析により分析した。</p><p><b>結果</b> 質的内容分析の結果, 126種類の意味単位が抽出された。グループ化により, (1) 不足する情報・十分でない情報共有に対する不安や不満, (2) 業務ならびに社会からの差別に対する心身の疲労, (3) 孤独と貧困に対する対応, (4) 感染予防対策における困難さ, の4テーマが抽出された。</p><p><b>結論</b> 本研究の結果から, 新興感染症拡大初期の現場で, 医療資材の不足だけでなく信頼性が高い情報の不足が特に深刻であった。また, 初期に限定した課題ではないが, 医療者の心身の疲労軽減, 孤独や貧困に対する生活支援も重要であった。</p>

    DOI: 10.24802/tpha.2022-02

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  18. 健診で血圧高値を指摘された高血圧症患者の疾患と治療に対する認識と態度 査読有り

    洪 英在, 平川 仁尚, 犬飼 麻里子, 水野 晴子, He Yupeng, 江 啓発, 八谷 寛

    東海公衆衛生雑誌   10 巻 ( 1 ) 頁: 180 - 186   2022年7月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:東海公衆衛生学会  

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  19. 特定健診およびレセプトデータを用いた愛知県岩倉市における心血管疾患発症リスクおよび人口寄与危険割合に関するコホート研究 査読有り

    He Yupeng, 江 啓発, 藤社 紗梨, 水野 晴子, 平川 仁尚, 八谷 寛

    東海公衆衛生雑誌   10 巻 ( 1 ) 頁: 166 - 179   2022年7月

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    担当区分:最終著者, 責任著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:東海公衆衛生学会  

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  20. Stoma creation is associated with a low incidence of midline incisional hernia after colorectal surgery: the "fighting over the fascia" theory concerning the incision and stoma hole. 査読有り 国際誌

    Ohara N, Uehara K, Ogura A, Sando M, Aiba T, Murata Y, Mizuno T, Toshio K, Yokoyama Y, Ishigaki S, Li Y, Yatsuya H, Ebata T

    Surgery today   52 巻 ( 6 ) 頁: 953 - 963   2022年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Surgery Today  

    Purpose: Parastomal hernia (PH) develops more frequently than incisional hernia (IH) after colorectal surgery with stoma. This study evaluated our hypothesis that inward traction of the fascia when closing a midline incision widens the stoma hole and increases the incidence of PH. Methods: A total of 795 patients who underwent colorectal resection between 2006 and 2016 were retrospectively analyzed. The risk classification was constructed from IH risk factors extracted from the non-stoma group. Then, the classification was extrapolated to the stoma group for predicting midline IH and PH. Results: The incidence of IH was 5.3% in the stoma group and 12.5% in the non-stoma group (p = 0.005). PH developed in 19.6% of 97 patients with permanent stoma. The risk classification was able to predict PH without a significant difference but was well balanced in patients with permanent stoma; however, it failed to predict IH in the stoma group. Conclusion: The risk classification constructed from the non-stoma group was useful for predicting not midline IH but PH, suggesting that the stoma site was the most vulnerable for herniation. The “fighting over the fascia” theory between the midline incision and stoma hole may explain the causal relationship between the midline IH and PH.

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  21. Prioritization and sequential exclusion of articles in systematic reviews 査読有り 国際共著 国際誌

    Saif-Ur-Rahman K.M., Hasan M., Hossain S., Anwar I., Hirakawa Y., Yatsuya H.

    Campbell Systematic Reviews   18 巻 ( 2 )   2022年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Campbell Systematic Reviews  

    It is difficult to match the causes of exclusion among two independent review authors after screening the title and abstract or full texts in systematic reviews. We have proposed the prioritization and sequential exclusion approach to reduce the subjectivity in reporting reasons for exclusion. This approach might reduce the burden of mismatched numbers while describing the cause of exclusion.

    DOI: 10.1002/cl2.1229

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  22. Implementation strategies for the patient safety reporting system using Consolidated Framework for Implementation Research: a retrospective mixed-method analysis.

    Koike D, Ito M, Horiguchi A, Yatsuya H, Ota A

    BMC health services research   22 巻 ( 1 ) 頁: 409   2022年3月

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    記述言語:英語   出版者・発行元:BMC Health Services Research  

    Background: Healthcare-related adverse events occur because of complex healthcare systems. The patient safety reporting system is a core component of patient safety initiatives in hospitals. However, hospital management often encounters a cultural barrier with its implementation and struggles to overcome the same. Implementation science would be useful for analysing implementation strategies. This study determines the effects of the implemented strategy on an increase in the number of patient safety reports and the determinants of successful implementation, using the implementation framework. Methods: Mixed method analysis was performed in Fujita Health University Hospital (FHUH), a large volume hospital in Japan. We identified strategies to implement the patient safety reporting system by scrutinising internal documents using the Consolidated Framework for Implementation Research (CFIR). The electronic reporting systems developed in 2004 in the FHUH and the number of reports were analysed using the staff data and hospital volumes. Results: Reports (n = 110,058) issued between April 2004 and March 2020 were analysed. The number of reports increased from 2004 to 2008 and from 2013 to 2019, reaching 14,037 reports per year. Between 2009 and 2012, the FHUH experienced a stagnation period where the number of reports were not increasing. From the qualitative materials, we identified 74 strategies which contributed to the implementation of the patient safety reporting system. Among these, the domain of ‘intervention characteristics’ in the CFIR contained 12 strategies, ‘outer settings’ contained 20, ‘inner settings’ contained 21, ‘characteristics of individuals’ contained 8, and ‘process’ contained 13. There were two concentrated periods of the implemented strategies, the number was 17 in 2007 and 10 in 2016. These concentrated periods preceded a remarkable increase in the number of patient safety reports. Conclusions: A safety culture had been fostered in FHUH in the study period. A relationship between number of strategies and development of a reporting culture was observed. The intensity of adequate strategies was needed for implementation of patient safety reporting system. Therefore, the implementation framework is useful for analysing patient safety initiatives for safety culture.

    DOI: 10.1186/s12913-022-07822-9

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  23. Applicability of a web-based 24-hour dietary recall tool for Japanese populations in large-scale epidemiological studies. 査読有り 国際誌

    Hose Y, Ishihara J, Kotemori A, Nakadate M, Maruya S, Tanaka J, Yatsuya H, Aoyama A, Chiang C, Konta T, Kayama T, Ueno Y, Inoue M, Sawada N, Tsugane S, Takachi R

    Journal of epidemiology   advpub 巻 ( 0 )   2022年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:日本疫学会  

    DOI: 10.2188/jea.JE20220071

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  24. Smoking cessation, weight gain and risk of cardiovascular disease. 査読有り 国際誌

    Wang X, Dong JY, Cui R, Muraki I, Shirai K, Yamagishi K, Kokubo Y, Saito I, Yatsuya H, Sawada N, Iso H, Tsugane S, Japan Public Health Center-based Prospective Study Group.

    Heart (British Cardiac Society)   108 巻 ( 5 ) 頁: 375 - 381   2022年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1136/heartjnl-2021-318972

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  25. 職業性ストレスと退職後の認知機能低下に関する縦断的研究 愛知職域コホート研究

    中島 啓裕, 江 啓発, 平川 仁尚, He Yupeng, 霜田 真子, 玉腰 浩司, 八谷 寛

    産業ストレス研究   29 巻 ( 1 ) 頁: 169 - 169   2022年3月

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    担当区分:最終著者, 責任著者   記述言語:日本語   掲載種別:研究論文(その他学術会議資料等)   出版者・発行元:日本産業ストレス学会  

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  26. Work and Family Conflicts, Depression, and "Ikigai": A Mediation Analysis in a Cross-Cultural Study Between Japanese and Egyptian Civil Workers. 査読有り 国際共著 国際誌

    Eshak ES, Baba S, Yatsuya H, Iso H, Hirakawa Y, Mahfouz EM, Chifa C, Sakaniwa R, El-Khateeb AS

    Journal of epidemiology   advpub 巻 ( 0 )   2022年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:日本疫学会  

    DOI: 10.2188/jea.JE20210338

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  27. Everyday wishes of older people living with dementia in care planning: a qualitative study.

    Mamun MR, Hirakawa Y, Saif-Ur-Rahman KM, Sakaguchi T, Chiang C, Yatsuya H

    BMC health services research   22 巻 ( 1 ) 頁: 184   2022年2月

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    記述言語:英語   出版者・発行元:BMC Health Services Research  

    Background: The dementia care policy in Japan emphasizes the views of people living with dementia in care planning. An exploration of the everyday wishes of older people living with dementia can help clarify their priorities and assist in improving dementia care. This study aimed to explore the everyday wishes of older people living with dementia in Japan. Methods: This qualitative study was conducted in Aichi prefecture in Japan. Older people with mild to moderate dementia were considered for inclusion. Participants were recruited from a dementia outpatient clinic. In-depth interviews were conducted with 36 participants in the same dementia outpatient clinic from January to October 2019. Audio-recorded interviews were transcribed verbatim. Inductive content analysis was carried out to analyze the data. Findings: Participants expressed their everyday wishes within five themes (desire of being connected, freedom to decide, involvement in activities, status quo, and self-reliance). Older people living with dementia loved the connection with their family and wanted to have an enjoyable life by engaging in several activities without others’ interference. They desired to maintain the status quo and not be a burden to others. Conclusions: This study provides evidence on the everyday wishes of people living with dementia. Identified wishes are mostly on emotional aspects of their daily lives. The findings of our study might help provide care for the people living with dementia considering their wishes. Further exploration, including people with severe dementia, is needed.

    DOI: 10.1186/s12913-022-07606-1

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  28. Age and sex differences in factors associated with hypertension among an urban poor population in Bangladesh.

    Al-Shoaibi AAA, Chiang C, Khalequzzaman M, Choudhury SR, Hirakawa Y, Islam SS, Aoyama A, Yatsuya H

    Nagoya journal of medical science   84 巻 ( 1 ) 頁: 69 - 79   2022年2月

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    記述言語:英語   出版者・発行元:Nagoya Journal of Medical Science  

    This study explores the differences in factors associated with hypertension between younger and older subjects in an urban slum community in Bangladesh. We analyzed the data of 1,008 men and 1,001 women obtained from a cross-sectional survey conducted between October 2015 and April 2016. Multivariable logistic regression models were stratified by age (18 to 44 and 45 to 64 years) in men and women separately. The multivariable model included age (continuous) and the following categorical variables simultaneously: education duration, marital status, tobacco smoking, smokeless tobacco use, total physical activity, body mass index (BMI), waist circumference, and the blood levels of glycated hemoglobin (HbA1c), triglycerides, high and low-density lipoprotein (HDL and LDL) cholesterol. Hypertension was defined as the presence of either blood pressure ≥140/90 mmHg or the use of antihypertensive medication. The prevalence of hypertension was 13.0% (younger men), 14.6% (younger women), 35.6% (older men), and 38.7% (older women). In younger men, higher waist circumference and increased LDL cholesterol levels were significantly associated with hypertension. In older men, physical activity was the only significant factor that was inversely associated with hypertension. In younger women, higher BMI, increased HbA1c, triglycerides, and LDL cholesterol levels were associated with hypertension. In older women, a higher HbA1c was the only factor significantly associated with hypertension. These findings suggest that public health interventions to prevent hypertension may require different approaches according to sex and age groups within the poor urban population in Bangladesh.

    DOI: 10.18999/nagjms.84.1.69

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  29. Comparison of laminoplasty and posterior fusion surgery for cervical ossification of posterior longitudinal ligament.

    Nakashima H, Imagama S, Yoshii T, Egawa S, Sakai K, Kusano K, Nakagawa Y, Hirai T, Wada K, Katsumi K, Fujii K, Kimura A, Furuya T, Kanchiku T, Nagamoto Y, Oshima Y, Nagoshi N, Ando K, Takahata M, Mori K, Nakajima H, Murata K, Matsunaga S, Kaito T, Yamada K, Kobayashi S, Kato S, Ohba T, Inami S, Fujibayashi S, Katoh H, Kanno H, Li Y, Yatsuya H, Koda M, Kawaguchi Y, Takeshita K, Matsumoto M, Yamazaki M, Okawa A, Japanese Multicenter Research Organization for Ossification of the Spinal Ligament.

    Scientific reports   12 巻 ( 1 ) 頁: 748   2022年1月

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    記述言語:英語   出版者・発行元:Scientific Reports  

    This prospective multicenter study, established by the Japanese Ministry of Health, Labour and Welfare and involving 27 institutions, aimed to compare postoperative outcomes between laminoplasty (LM) and posterior fusion (PF) for cervical ossification of the posterior longitudinal ligament (OPLL), in order to address the controversy surrounding the role of instrumented fusion in cases of posterior surgical decompression for OPLL. 478 patients were considered for participation in the study; from among them, 189 (137 and 52 patients with LM and PF, respectively) were included and evaluated using the Japanese Orthopaedic Association (JOA) scores, the JOA Cervical Myelopathy Evaluation Questionnaire (JOACMEQ), and radiographical measurements. Basic demographic and radiographical data were reviewed, and the propensity to choose a surgical procedure was calculated. Preoperatively, there were no significant differences among the participants in terms of patient backgrounds, radiographical measurements (K-line or cervical alignment on X-ray, OPLL occupation ratio on computed tomography, increased signal intensity change on magnetic resonance imaging), or clinical status (JOA score and JOACMEQ) after adjustments. The overall risk of perioperative complications was found to be lower with LM (odds ratio [OR] 0.40, p = 0.006), and the rate of C5 palsy occurrence was significantly lower with LM (OR 0.11, p = 0.0002) than with PF. The range of motion (20.91° ± 1.05° and 9.38° ± 1.24°, p < 0.0001) in patients who had PF was significantly smaller than in those who had LM. However, multivariable logistic regression analysis showed no significant difference among the participants in JOA score, JOA recovery rate, or JOACMEQ improvement at two years. In contrast, OPLL progression was greater in the LM group than in the PF group (OR 2.73, p = 0.0002). Both LM and PF for cervical myelopathy due to OPLL had resulted in comparable postoperative outcomes at 2 years after surgery.

    DOI: 10.1038/s41598-021-04727-1

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  30. Association between long-term alcohol consumption and insomnia symptoms in civil servants: Aichi Workers’ Cohort Study 査読有り 国際誌

    Terabe Motoi, Kitajima Tsuyoshi, Ota Atsuhiko, Yatsuya Hiroshi, Iwata Nakao

    Fujita Medical Journal   advpub 巻 ( 0 )   2022年

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Fujita Medical Society  

    <p><b>Objectives:</b> The influence of habitual alcohol consumption on insomnia symptoms in healthy workers remains unclear. In this study, we evaluated the association between habitual alcohol consumption among civil servants and insomnia symptoms such as difficulty falling asleep, difficulty staying asleep, and tiredness after sleep, using longitudinal data.</p><p><b>Methods:</b> We enrolled civil servants in a prospective cohort study who completed questionnaires at baseline. Of those, 2861 participants were revaluated in a 5-year follow-up survey. Insomnia symptoms during the past month were assessed using self-reporting. Alcohol drinking habits were assessed by querying the frequency of drinking alcohol as well as the amount of alcohol usually consumed per one occasion.</p><p><b>Results:</b> Drinking alcohol every day was less likely to have difficulty falling asleep (odds ratio, 0.42 95% confidence interval, 0.20–0.89), and drinking alcohol 3 or more days a week was associated with difficulty staying asleep (odds ratio, 1.48; 95% confidence interval, 1.16–1.90).</p><p><b>Conclusions:</b> Drinking alcohol every day may produce subjective improvement in sleep onset. However, drinking alcohol 3 or more days a week may increase arousal during sleep, which contributes to reduced sleep quality. These results suggest the possibility that long-term daily habitual drinking may reinforce a sense of improvement in subjective sleep onset but may possibly induce sleep disturbance.</p>

    DOI: 10.20407/fmj.2021-015

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  31. Association between C-reactive protein and risk of overall and 18 site-specific cancers in a Japanese case-cohort

    Suzuki S., Katagiri R., Yamaji T., Sawada N., Imatoh T., Ihira H., Inoue M., Tsugane S., Iwasaki M., Sawada N., Tsugane S., Iwasaki M., Inoue M., Yamaji T., Katagiri R., Miyamoto Y., Abe S.K., Tanaka S., Moriya T., Minamizono T., Shirai Y., Kuniyoshi H., Yoshimi T., Sonoda H., Tagami T., Ando T., Kimura T., Kokubo Y., Yamagishi K., Mizoue T., Nakamura K., Takachi R., Ishihara J., Iso H., Kitamura T., Saito I., Yasuda N., Mimura M., Sakata K., Noda M., Goto A., Yatsuya H.

    British Journal of Cancer     2022年

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    記述言語:日本語   出版者・発行元:British Journal of Cancer  

    Background: Evidence of the association between chronic low-grade inflammation, as reflected by C-reactive protein (CRP) measurements, and cancer risk is equivocal. Specifically, few studies have examined this in uncommon cancers and Asian populations. Methods: We utilised a case-cohort design consisting of multi-types of cancer (N = 3608), and a random subcohort (N = 4432) in a Japanese large population-based study, with a median follow-up time of 15.6 years, and measured baseline plasma CRP using high sensitivity assay. The hazard ratios (HRs) were estimated using weighted Cox proportional hazards methods. Results: The multivariable-adjusted HR (95% confidence interval) for the top quartile of CRP was 1.28 (1.11‒1.48) (Ptrend < 0.001) for overall cancer compared to the bottom quartile of CRP. Among site-specific cancers, higher CRP levels were associated with an increased risk of colorectal, lung, breast, biliary tract, and kidney cancer, and leukaemia. These positive associations remained among participants after >3 years’ follow-up. Furthermore, subgroup analyses for overall cancer robustly showed a positive association with CRP levels, regardless of sex and obesity. Conclusion: Our consistent findings suggested that chronic low-grade inflammation measured by CRP is associated with the risk of cancer.

    DOI: 10.1038/s41416-022-01715-8

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  32. High Maternal Total Cholesterol Is Associated With No-Catch-up Growth in Full-Term SGA Infants: The Japan Environment and Children's Study. 査読有り 国際誌

    Kaneko K, Ito Y, Ebara T, Kato S, Matsuki T, Tamada H, Sato H, Saitoh S, Sugiura-Ogasawara M, Yatsuya H, Kamijima M

    Frontiers in endocrinology   13 巻   頁: 939366 - 939366   2022年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Frontiers in Endocrinology  

    Objectives: Infants born small for gestational age (SGA) with no catch-up growth (No-CU) are at high risk of intellectual and developmental disabilities. However, factors leading to No-CU among SGA infants are unclear. This study aimed to examine the association between maternal total cholesterol (TC) in mid-pregnancy and No-CU at 3 years among full-term SGA infants. Study Design: The Japan Environment and Children’s Study (JECS) is a nationwide prospective birth cohort study. We extracted a total of 2,222 mothers and full-term SGA infants (length and/or weight <‐2 standard deviation [SD]) without congenital abnormalities from the original JECS cohort comprising a total of 104,062 fetal records. According to the distribution of maternal TC in the entire cohort, participants were classified into nine groups per each fifth percentile with the 20th–79th percentiles (204–260 mg/dl) as the reference group. No-CU was defined by a Z-score of height at 3 years <‐2 SD according to the growth standard charts for Japanese children. Multivariable-adjusted logistic regression models were carried out using multiple imputations. Additionally, a multiple-adjusted restricted cubic spline model was performed in the complete dataset. Results: A total of 362 (16.3%) children were No-CU at 3 years. After adjusting for the Z-score of birth weight, age of mother, smoking status, weight gain during pregnancy, breastfeeding and meal frequency at 2 years, and parents’ heights, the odds ratio (95% confidence intervals) of No-CU was 2.95 (1.28–6.80) for children whose maternal TC levels were in the highest category (≥294 mg/dl), compared to the reference group. A multiple-adjusted restricted cubic spline model showed a non-linear trend of the significant association between high maternal TC and No-CU (p for linear trend = 0.05, p for quadratic trend <0.05). Conclusion: High maternal TC at mid-pregnancy was associated with No-CU among SGA infants. Such infants should be carefully followed up to introduce appropriate growth hormonal treatment. The findings may support previous animal experimental studies which indicated that maternal high-fat diet exposure induces impairment of growth and skeletal muscle development in the offspring. Future studies are required to elucidate the detailed mechanism.

    DOI: 10.3389/fendo.2022.939366

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  33. Prediction of Lifetime Risk of Cardiovascular Disease Deaths Stratified by Sex in the Japanese Population 査読有り 国際誌

    Yukiko Imai, Sachiko Mizuno Tanaka, Michihiro Satoh, Takumi Hirata, Yoshitaka Murakami, Katsuyuki Miura, Takashi Waki, Aya Hirata, Toshimi Sairenchi, Fujiko Irie, Mizuki Sata, Toshiharu Ninomiya, Takayoshi Ohkubo, Shizukiyo Ishikawa, Yoshihiro Miyamoto, Hirofumi Ohnishi, Shigeyuki Saitoh, Akiko Tamakoshi, Michiko Yamada, Masahiko Kiyama, Hiroyasu Iso, Kiyomi Sakata, Hideaki Nakagawa, Akira Okayama, Hirotsugu Ueshima, Tomonori Okamura, Yutaka Imai, Akihiko Kitamura, Yutaka Kiyohara, Akiko Harada, Masaru Sakurai, Takeo Nakayama, Ichiro Tsuji, Yoshihiro Kokubo, Hiroshi Yatsuya, Tomonori Okamura

    Journal of the American Heart Association   10 巻 ( 23 )   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Ovid Technologies (Wolters Kluwer Health)  

    <sec xml:lang="en">
    <title>Background</title>
    <p xml:lang="en">Lifetime risk is an informative estimate for driving lifestyle and behavioral changes especially for young adults. The impact of composite risk factors for cardiovascular disease on lifetime risk stratified by sex has not been investigated in the Japanese population, which has a much lower mortality of coronary heart disease compared with the Western population. We aimed to estimate lifetime risk of death from cardiovascular disease attributable to traditional risk factors.


    </sec>
    <sec xml:lang="en">
    <title>Methods and Results</title>
    <p xml:lang="en">We analyzed pooled individual data from the Evidence for Cardiovascular Prevention from Observational Cohorts in a Japanese cohort study. A modified Kaplan–Meier approach was used to estimate the remaining lifetime risk of cardiovascular death. In total, 41 002 Japanese men and women with 537 126 person‐years of follow‐up were included. The lifetime risk at the index‐age of 45 years for those with optimal risk factors (total cholesterol &lt;4.65 mmol/L, systolic blood pressure &lt;120 mm Hg, diastolic blood pressure &lt;80 mm Hg, absence of diabetes, and absence of smoking habit) was lower compared with the highest risk profile of ≥2 risk factors (6.8% [95% CI, 0%–11.9%] versus 19.4% [16.7%–21.4%] for men and 6.9% [1.2%–11.5%] versus 15.4% [12.6%–18.1%] for women).


    </sec>
    <sec xml:lang="en">
    <title>Conclusions</title>
    <p xml:lang="en">The magnitude and the number of risk factors were progressively associated with increased lifetime risk even in individuals in early adulthood who tend to have low short‐term risk. The degree of established cardiovascular risk factors can be converted into lifetime risk. Our findings may be useful for risk communication in the early detection of future cardiovascular disease risk.


    </sec>

    DOI: 10.1161/jaha.121.021753

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  34. The Association of Work-related Stress According to the Demand-Control Model With Aggravation of Pre-existing Disease During the First State of COVID-19 Emergency in Japan. 査読有り 国際誌

    He Y, Yatsuya H, Chiang C, Ota A, Okubo R, Ishimaru T, Tabuchi T

    Journal of epidemiology   31 巻 ( 12 ) 頁: 642 - 647   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Epidemiology  

    Background: The job environment has changed a lot during the period of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to investigate the association between work-related stress and aggravation of pre-existing disease in workers during the first state of COVID-19 emergency in Japan. Methods: Data were obtained from a large internet survey conducted between August 25 and September 30, 2020 in Japan. Participants who reported that they had a job as well as current history of disease(s) (ie, pre-existing conditions) were included (n = 3,090). Aggravation of pre-existing disease during the state of emergency was self-reported. Work-related stress from April 2020 (since the state of COVID-19 emergency) was assessed according to a job demand–control model. Multivariable logistic regression models were used to analyze the association. Results: Aggravation of pre-existing diseases was reported by 334 participants (11%). The numbers of participants with high demand and low control were 112 (18%) and 100 (14%), respectively. Compared to medium demand, high demand was significantly associated with aggravation of pre-existing diseases (odds ratio 1.77; 95% confidence interval, 1.30–2.42). Low control compared to medium control was also significantly associated with aggravation of pre-existing diseases (odds ratio 1.39; 95% confidence interval, 1.02–1.92). Conclusion: Work-related stress during the first state of COVID-19 emergency was associated with aggravation of pre-existing disease during that period.

    DOI: 10.2188/jea.JE20210146

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  35. Working cancer survivors' physical and mental characteristics compared to cancer-free workers in Japan: a nationwide general population-based study. 査読有り 国際誌

    Ota A, Li Y, Yatsuya H, Tanno K, Sakata K, Yamagishi K, Iso H, Yasuda N, Saito I, Kato T, Arima K, Sou Y, Shimazu T, Yamaji T, Goto A, Inoue M, Iwasaki M, Sawada N, Tsugane S, JPHC-NEXT Study Group.

    Journal of cancer survivorship : research and practice   15 巻 ( 6 ) 頁: 912 - 921   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Cancer Survivorship  

    Purpose: This study compared working cancer survivors’ self-rated health status (SRHS), physical functional capacity, depressive symptoms, and happiness to those of cancer-free workers. Methods: A nationwide general population-based cross-sectional study on a sample of Japanese was conducted. Prevalence of deteriorated SRHS, restricted physical functional capacity, depressive symptoms, and perceived happiness were compared between working cancer survivors and cancer-free workers with multivariable logistic regression analysis adjusted for age and sociodemographic and health-related backgrounds. Results: Of the 28,311 male and 26,068 female workers, 977 (3.5%) and 1267 (4.9%) were cancer survivors, respectively. Working cancer survivors reported deteriorated SRHS more frequently than cancer-free workers: 21.3% vs. 13.8%, multivariable-adjusted odds ratio (95% confidence interval), 1.64 (1.39–1.95) for men, 23.8% vs. 17.5%, 1.34 (1.16–1.54) for women. Restricted physical functional capacity was reported more frequently in working cancer survivors than cancer-free workers: 6.8% vs. 2.6%, 1.76 (1.34–2.32) for men, 4.9% vs. 2.0%, 2.06 (1.56–2.71) for women. No significant difference was found for depressive symptoms: 21.6% vs. 22.9% in men, 30.0% vs. 28.5% in women. Working cancer survivors felt happiness more frequently than cancer-free survivors in men (77.3% vs. 71.7%, 1.21 (1.01–1.45)) but not in women (76.1% vs. 74.9%). Conclusions: Working cancer survivors had worse SRHS and more restricted physical functional capacity than cancer-free workers. In men, working cancer survivors felt happiness more frequently than cancer-free workers. Implications for Cancer Survivors: Continuous support to improve cancer survivors’ SRHS and physical functional capacity would be necessary even while they are working.

    DOI: 10.1007/s11764-020-00984-7

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  36. Seasonal variation in submacular hemorrhages in retinal macroaneurysms and its disappearance in age-related macular degeneration.

    Kaneko H, Takashi N, Matsunaga M, Ito Y, Takeuchi J, Terasaki H, Yatsuya H, Nishiguchi KM

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie   259 巻 ( 12 ) 頁: 3589 - 3596   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Graefe's Archive for Clinical and Experimental Ophthalmology  

    Purpose: To investigate whether previously reported seasonal variation and winter-dominant prevalence of acute massive submacular hemorrhages (SMHs) caused by age-related macular degeneration (AMD) disappeared, and those caused by retinal microaneurysms (RMAs) emerged. Method: The medical charts of 95 patients (95 eyes) with SMH caused by AMD and 76 patients (76 eyes) with SMH caused by RMAs in 2012–2019 were retrospectively reviewed. For each subject, the month of onset, the mean ambient temperature of that month were recorded. Results: The monthly numbers of cases of SMHs caused by AMD from January to December were 6, 8, 4, 9, 7, 10, 9, 11, 7, 11, 3, and 10. No significant seasonal variation in the monthly incidence was identified (Roger’s R = 1.89, p = 0.39). The monthly numbers of SMHs caused by RMAs from January to December were 3, 11, 11, 8, 7, 8, 5, 5, 2, 4, 7, and 5. There was significant seasonal variation in the monthly incidence (Roger’s R = 7.67, p = 0.02). There was no significant correlation between the monthly incidence of SMHs caused by RMAs and mean ambient temperature. Conclusion: Our previous study conducted for cases obtained in 1998–2005 showed seasonal cyclic trend in the number of SMHs caused by AMD, with the peak in winter. However, that significant seasonal variation disappeared in 2012–2019 in the present study. Common usage of OCT devices and anti-VEGF drugs might be the reason for the lack of seasonal variation in the cases of SMH caused by AMD. [Figure not available: see fulltext.]

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  37. Peanut Consumption and Risk of Stroke and Ischemic Heart Disease in Japanese Men and Women: The JPHC Study. 査読有り 国際誌

    Ikehara S, Iso H, Kokubo Y, Yamagishi K, Saito I, Yatsuya H, Kimura T, Sawada N, Iwasaki M, Tsugane S, JPHC Study Group.

    Stroke   52 巻 ( 11 ) 頁: 3543 - 3550   2021年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Stroke  

    Background and Purpose: Several prospective cohort studies and a randomized clinical trial have shown the beneficial effects of peanut consumption on cardiovascular disease and its risk factors. We examined the association between peanut consumption and risk of cardiovascular disease in Japanese men and women. Methods: We analyzed data of 74 793 participants aged 45 to 74 years who completed a lifestyle questionnaire including the validated food frequency questionnaire in the Japan Public Health Center-based Prospective Study. They were followed up from 1995 to 2009 for cohort I and from 1998 to 1999 to 2012 for cohort II. Peanut consumption was calculated from the food frequency questionnaire, and the end points were incidence of stroke, ischemic heart disease, and cardiovascular disease (stroke and ischemic heart disease). Results: During a median follow-up of 14.8 years, 3,599 strokes and 849 ischemic heart diseases were reported. Higher peanut consumption was associated with reduced risks of total stroke, ischemic stroke, and cardiovascular disease among men and women. The multivariable hazard ratios (95% CIs) for the highest versus lowest quartiles of peanut consumption after adjustment for age, sex, public health center, smoking, alcohol consumption, perceived stress level, physical activity, vegetable, fruit, fish, soy, sodium and total energy intakes, body mass index, history of hypertension, history of diabetes, and cholesterol-lowering drug were 0.84 (0.77-0.93, P for trend=0.002) for total stroke, 0.80 (0.71-0.90, P for trend=0.002) for ischemic stroke, 0.93 (0.79-1.08, P for trend=0.27) for hemorrhagic stroke, 0.97 (0.80-1.17, P for trend=0.81) for ischemic heart disease and 0.87 (0.80-0.94, P for trend=0.004) for cardiovascular disease, and these associations were similarly observed in both sexes. Conclusions: Higher peanut consumption was associated with reduced risk of stroke, especially ischemic stroke, but not ischemic heart disease in Japanese men and women.

    DOI: 10.1161/STROKEAHA.120.031212

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  38. Having hobbies and the risk of cardiovascular disease incidence: A Japan public health center-based study. 国際誌

    Wang X, Dong JY, Shirai K, Yamagishi K, Kokubo Y, Saito I, Yatsuya H, Iso H, Tsugane S, Sawada N, Japan Public Health Center-based Prospective Study Group.

    Atherosclerosis   335 巻   頁: 1 - 7   2021年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.atherosclerosis.2021.09.002

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  39. アポリポ蛋白A2のアイソフォームと心筋梗塞発症との関連に関するコホート内症例対照研究 多目的コホート(JPHC)研究

    木原 朋未, 山岸 良匡, 本田 一文, 池田 愛, 八谷 寛, 斉藤 功, 小久保 喜弘, 山地 太樹, 島津 太一, 澤田 典絵, 岩崎 基, 磯 博康, 津金 昌一郎

    日本動脈硬化学会総会プログラム・抄録集   53回 巻   頁: 232 - 232   2021年10月

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    記述言語:日本語   掲載種別:研究論文(その他学術会議資料等)   出版者・発行元:(一社)日本動脈硬化学会  

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  40. Association of anthropometric indices of obesity with hypertension among public employees in northern Ethiopia: findings from a cross-sectional survey.

    Saif-Ur-Rahman KM, Chiang C, Weldegerima Gebremariam L, Haregot Hilawe E, Hirakawa Y, Aoyama A, Yatsuya H

    BMJ open   11 巻 ( 9 ) 頁: e050969   2021年9月

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    記述言語:英語   出版者・発行元:BMJ Open  

    Objectives: The burden of hypertension is increasing in low-income countries, including Ethiopia. Obesity is widely known to be associated with hypertension, but different anthropometric indices of obesity might differ in association with hypertension, which is largely unknown in northern Ethiopia. Design: Data from our previous cross-sectional epidemiological survey were statistically analysed. Setting: Public employees in the regional capital city in northern Ethiopia. Participants: The data of 1380 participants (823 men and 557 non-pregnant women) aged 25 and 64 years were analysed. Outcome measures: The presence of hypertension was the outcome measure and multivariable-adjusted logistic regression analyses were used to investigate the association of body mass index (BMI), waist circumference, and waist-hip ratio in men and women separately. The area under the curve (AUC) for three anthropometric indices for discriminating hypertension was also obtained. Separate analyses were conducted for waist circumference and waist-hip ratio analyses further adjusted for BMI. Results: BMI was linearly associated with hypertension in men (OR for 1 SD increase in BMI 1.45, p=0.001) and women (OR for 1 SD increase in BMI 1.41, p=0.01). The association of waist circumference was independent of BMI both in men (OR for 1 SD increase in waist circumference: 1.74, p=0.002) and women (OR for 1 SD increase in waist circumference: 1.57, p=0.029). The association of waist-hip ratio with hypertension adjusted for BMI was significant in men (OR for 1 SD increase in the waist-hip ratio: 1.46, p<0.001), but was weak and non-significant in women. The AUC for BMI was 0.64 in men and 0.67 in women, while AUC for waist circumference was 0.69 both in men and women. Conclusions: Waist circumference was associated with hypertension independent of BMI among public employees in northern Ethiopia.

    DOI: 10.1136/bmjopen-2021-050969

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  41. Associations of insomnia with noise annoyance and neighborhood environments: A nationwide cross-sectional study in Japan. 国際誌

    Hanibuchi T, Nakaya T, Kitajima T, Yatsuya H

    Preventive medicine reports   23 巻   頁: 101416 - 101416   2021年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Preventive Medicine Reports  

    Despite the increasing knowledge on the association between neighborhood and health, few studies have investigated sleep disorders in Japan, particularly the impact of neighborhood noise on sleep. Thus, this study aimed to investigate the associations between insomnia symptoms and annoyance because of traffic and neighborhood noise in Japan, which has different neighborhood conditions compared with those of the western societies. Neighborhood built and socioeconomic environments roles were also examined. We used nationwide cross-sectional data collected through a 2015 online survey of Japanese adults aged 20–64 years (n = 4,243). Adjusted prevalence ratios for insomnia according to the exposures were estimated using the multilevel Poisson regression models. The results showed that having insomnia was significantly associated with experiencing neighborhood and traffic-noise annoyance. Neighborhood noise had a stronger and independent association with insomnia. However, the neighborhood environmental variables, including population density, deprivation index, and access to commercial areas, were not associated with insomnia. In conclusion, noise annoyance, particularly that sourced from neighbors, is an important factor in relation to sleep health. Health and urban-planning policymakers should consider neighborhood noise, in addition to traffic noise, as health-related issues in residential neighborhoods.

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  42. Estimation of 10-Year Risk of Death from Coronary Heart Disease, Stroke, and Cardiovascular Disease in a Pooled Analysis of Japanese Cohorts: EPOCH-JAPAN. 査読有り 国際誌

    Li Y, Yatsuya H, Tanaka S, Iso H, Okayama A, Tsuji I, Sakata K, Miyamoto Y, Ueshima H, Miura K, Murakami Y, Okamura T

    Journal of atherosclerosis and thrombosis   28 巻 ( 8 ) 頁: 816 - 825   2021年8月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Atherosclerosis and Thrombosis  

    Aims: We aimed to develop and validate risk prediction models to estimate the absolute 10-year risk of death from coronary heart disease (CHD), stroke, and cardiovascular disease (CVD). Methods: We evaluated a total of 44,869 individuals aged 40-79 years from eight Japanese prospective cohorts to derive coefficients of risk equations using cohort-stratified Cox proportional hazard regression models. Discrimination (C-index) of the equation was examined in each cohort and summarised using random-effect metaanalyses. Calibration of the equation was assessed using Hosmer-Lemeshow chi-squared statistic. Results: Within a median follow-up of 12.7 years, we observed 765 deaths due to CVD (276 CHDs and 489 strokes). After backward selection, age, sex, current smoking, systolic blood pressure (SBP), proteinuria, prevalent diabetes mellitus, the ratio of total cholesterol to high-density lipoprotein cholesterol (TC/HDLC), interaction terms of age by SBP, and age by current smoking were retained as predictors for CHD. Sex was excluded in the stroke equation. We did not consider TC/HDLC as a risk factor for the stroke and CVD equations. The pooled C-indices for CHD, stroke, and CVD were 0.83, 0.80, and 0.81, respectively, and the corresponding p-values of the Hosmer-Lemeshow tests were 0.18, 0.003, and 0.25, respectively. Conclusions: Risk equations in the present study can adequately estimate the absolute 10-year risk of death from CHD, stroke, and CVD. Future work will evaluate the system as an education and risk communication tool for primary prevention of CHD and stroke.

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  43. 小学2年非肥満児における男女別の推定食塩摂取量、尿中Na/K比と収縮期血圧の関連

    金子 佳世, 伊藤 由起, 加藤 沙耶香, 玉田 葉月, 松木 太郎, 榎原 毅, 井上 貴子, 杉浦 真弓, 齋藤 伸治, 八谷 寛, 藤田 直也, 上島 通浩

    東海公衆衛生雑誌   9 巻 ( 1 ) 頁: 49 - 49   2021年7月

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    記述言語:日本語   掲載種別:研究論文(その他学術会議資料等)   出版者・発行元:東海公衆衛生学会  

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  44. The Association between Adult Height and Stroke Incidence in Japanese Men and Women: A Population- Based Case- Control Study. 査読有り 国際誌

    Kondo Y, Yatsuya H, Ota A, Matsumoto S, Ueda A, Watanabe H, Toyoshima H

    Journal of epidemiology   advpub 巻 ( 0 )   2021年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:日本疫学会  

    <p>Background: No studies have examined the associations between adult height and ischemic stroke subtypes.</p><p>Methods: We conducted a population-based case-control study that included 2,451 thrombotic and 687 embolic stroke cases, as well as 1,623 intracerebral and 768 subarachnoid hemorrhage cases without history of stroke aged 40-79 years, and the same number of sex- and age-matched controls. Cases and controls were grouped according to the quintile cut-off values of height in controls, and the third quintile, which was approximately the average height group, was used as the reference group. Height was also examined as a continuous variable as divided by one standard deviation of height in controls. The analyses were carried out separately for participants aged 40-59 years and 60-79 years.</p><p>Results: In both younger and older men, continuous height was linearly inversely associated with total and thrombotic strokes, and the shortest quintile compared to the reference was associated with increased risks of these strokes. Although height was linearly inversely associated with embolic stroke and intracerebral hemorrhage in younger men, the shortest quintile did not show increased risks of these strokes. Height did not seem to be associated with total stroke and any stroke subtypes in younger women. In contrast, the tallest quintile was significantly associated with increased risks of total stroke and intracerebral hemorrhage, and height tended to be positively associated with these strokes in older women.</p><p>Conclusions: We reported the associations between adult height and ischemic stroke subtypes for the first time, which differed according to sex and age-group.</p>

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  45. Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019

    Reitsma M.B., Kendrick P.J., Ababneh E., Abbafati C., Abbasi-Kangevari M., Abdoli A., Abedi A., Abhilash E.S., Abila D.B., Aboyans V., Abu-Rmeileh N.M., Adebayo O.M., Advani S.M., Aghaali M., Ahinkorah B.O., Ahmad S., Ahmadi K., Ahmed H., Aji B., Akunna C.J., Al-Aly Z., Alanzi T.M., Alhabib K.F., Ali L., Alif S.M., Alipour V., Aljunid S.M., Alla F., Allebeck P., Alvis-Guzman N., Amin T.T., Amini S., Amu H., Amul G.G.H., Ancuceanu R., Anderson J.A., Ansari-Moghaddam A., Antonio C.A.T., Antony B., Anvari D., Arabloo J., Arian N.D., Arora M., Asaad M., Ausloos M., Awan A.T., Ayano G., Aynalem G.L., Azari S., B D.B., Badiye A.D., Baig A.A., Bakhshaei M.H., Banach M., Banik P.C., Barker-Collo S.L., Bärnighausen T.W., Barqawi H.J., Basu S., Bayati M., Bazargan-Hejazi S., Behzadifar M., Bekuma T.T., Bennett D.A., Bensenor I.M., Berfield K.S.S., Bhagavathula A.S., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bibi S., Bijani A., Bintoro B.S., Biondi A., Birara S., Braithwaite D., Brenner H., Brunoni A.R., Burkart K., Butt Z.A., Caetano dos Santos F.L., Cámera L.A., Car J., Cárdenas R., Carreras G., Carrero J.J., Castaldelli-Maia J.M., Cattaruzza M.S.S., Chang J.C., Chen S., Chu D.T., Chung S.C., Cirillo M., Costa V.M., Couto R.A.S., Dadras O., Dai X., Damasceno A.A.M., Damiani G., Dandona L.

    The Lancet   397 巻 ( 10292 ) 頁: 2337 - 2360   2021年6月

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    記述言語:日本語   出版者・発行元:The Lancet  

    Background: Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods: We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings: Globally in 2019, 1·14 billion (95% uncertainty interval 1·13–1·16) individuals were current smokers, who consumed 7·41 trillion (7·11–7·74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. Globally in 2019, smoking tobacco use accounted for 7·69 million (7·16–8·20) deaths and 200 million (185–214) disability-adjusted life-years, and was the leading risk factor for death among males (20·2% [19·3–21·1] of male deaths). 6·68 million [86·9%] of 7·69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation: In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a clear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Funding: Bloomberg Philanthropies and the Bill & Melinda Gates Foundation.

    DOI: 10.1016/S0140-6736(21)01169-7

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  46. What constitutes healthiness of Washoku or Japanese diet? 招待有り 査読有り

    Yatsuya H, Tsugane S

    European journal of clinical nutrition   75 巻 ( 6 ) 頁: 863 - 864   2021年6月

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    記述言語:英語   出版者・発行元:European Journal of Clinical Nutrition  

    DOI: 10.1038/s41430-021-00872-y

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  47. Predictive risk factors for pneumothorax after transbronchial biopsy using endobronchial ultrasonography with a guide sheath. 国際誌

    Gotoh Y, Yamaguchi T, Yatsuya H, Ikeda A, Okamura T, Sakakibara Y, Ina T, Maeda Y, Hirochi M, Kako H, Goto Y, Isogai S, Yamamoto N, Kondo M, Imaizumi K

    BMC pulmonary medicine   21 巻 ( 1 ) 頁: 181 - 181   2021年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMC Pulmonary Medicine  

    Background: Pneumothorax is one complication of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS-TBB). We sought to clarify the risk factors for pneumothorax after EBUS-GS-TBB under fluoroscopic guidance. Methods: We retrospectively reviewed data from 916 patients who underwent EBUS-GS-TBB at Fujita Health University Hospital. We evaluated the following risk factors for pneumothorax after EBUS-GS-TBB: patient characteristics (sex, age, and pulmonary comorbidities); lesion data (location, size, existence of ground-glass opacities [GGOs], pleural involvement, computed tomography [CT] bronchus sign, visibility on fluoroscopy, and EBUS findings); final diagnosis; years of bronchoscopist experience; and guide sheath size. Univariate and multivariate logistic regression analyses were performed. Results: Among the 916 patients, 30 (3.28%) presented with pneumothorax. With a univariate analysis, factors that independently predisposed to pneumothorax included lesions containing GGOs, lesions in sagittal lung segments on fluoroscopy, lesions that were not visible on fluoroscopy, and infectious lesions. A univariate analysis also showed that lesions in the right upper lobe or left upper division, as well as malignant lesions, were less likely to lead to pneumothorax. Age, underlying pulmonary disease, CT bronchus sign, EBUS findings, bronchoscopist experience, and guide sheath size did not influence the incidence of pneumothorax. A multivariate analysis revealed that only lesions containing GGOs (odds ratio [OR] 6.47; 95% confidence interval [CI] 2.13–19.6, P = 0.001) and lesions in lung segments with a sagittal orientation on fluoroscopy (OR 2.47; 95% CI 1.09–5.58, P = 0.029) were significant risk factors for EBUS-GS-TBB-related pneumothorax. Conclusions: EBUS-GS-TBB of lesions containing GGOs or lesions located in sagittal lung segments on fluoroscopy correlate with a higher pneumothorax risk.

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  48. Inherited Chromosomally Integrated Human Herpesvirus 6 Is a Risk Factor for Spontaneous Abortion. 査読有り 国際誌

    Miura H, Kawamura Y, Ohye T, Hattori F, Kozawa K, Ihira M, Yatsuya H, Nishizawa H, Kurahashi H, Yoshikawa T

    The Journal of infectious diseases   223 巻 ( 10 ) 頁: 1717 - 1723   2021年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/infdis/jiaa606

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  49. Prevalence of and factors associated with dilated choroidal vessels beneath the retinal pigment epithelium among the Japanese.

    Ito Y, Ito M, Iwase T, Kataoka K, Yamada K, Yasuda S, Ito H, Takeuchi J, Nakano Y, Fujita A, Horiguchi E, Taki Y, Yatsuya H, Terasaki H

    Scientific reports   11 巻 ( 1 ) 頁: 11278   2021年5月

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    記述言語:英語   出版者・発行元:Scientific Reports  

    Pachyvessels are pathologically dilated large choroidal vessels and are associated with the pathogenesis of several pachychoroid-related disorders, including central serous chorioretinopathy. We aimed to investigate the prevalence of and risk factors for pachyvessels in the Japanese population. We included 316 participants (aged ≥ 40 years) with normal right eyes. The presence of pachyvessels (vertical diameter > 300 µm, distance to the retinal pigment epithelium < 50 µm) was determined using 6 × 6 mm macular swept-source optical coherence tomography images, and associated risk factors were investigated. Subfoveal choroidal thickness was measured, and its associated risk factors investigated. The overall prevalence of pachychoroids was 9.5%. Regression analysis showed that a younger age, shorter axial length, male sex, and smoking were significantly associated with the presence of pachyvessels (p = 0.047; odds ratio [OR] 0.96 per year, p = 0.021; OR 0.61 per 1 mm, p = 0.012; OR 3.08 vs. female, and p = 0.011; OR 3.15 vs. non-smoker, respectively) and greater choroidal thickness (p < 0.001, p < 0.001, p < 0.003, and p < 0.017, respectively). The results were consistent with other research findings which showed that pachychoroid-related disorders such as central serous chorioretinopathy were associated with younger age, male sex, shorter axial length, and smoking. Smoking may be associated with choroidal circulatory disturbance in the Japanese population.

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  50. Relationship between fasting blood glucose levels in middle age and cognitive function in later life: The Aichi Workers' Cohort Study.

    Shimoda M, Kaneko K, Nakagawa T, Kawano N, Otsuka R, Ota A, Naito H, Matsunaga M, Ichino N, Yamada H, Chiang C, Hirakawa Y, Tamakoshi K, Aoyama A, Yatsuya H

    Journal of epidemiology   advpub 巻 ( 0 )   2021年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:日本疫学会  

    <p><b>Background:</b> There is limited evidence regarding the relationship between Diabetes mellitus (DM) in middle age and mild cognitive impairment after a follow-up. Therefore, we investigated the relationship between fasting blood glucose (FBG) levels in middle age and cognitive function (assessed using the Japanese version of the Montreal Cognitive Assessment (MoCA-J) in later life, following over 15 years of follow-up in the Aichi Workers' Cohort Study in Japan.</p><p><b>Methods:</b> Participants were 253 former local government employees aged 60–79 years in 2018 who participated in a baseline survey conducted in 2002. Using baseline FBG levels and self-reported history, participants were classified into the normal, impaired fasting glucose (IFG) and, and DM groups. Total MoCA-J score ranges from 0 to 30, and cognitive impairment was defined as MoCA-J score ≤25 in this study. A general linear model was used to estimate the mean MoCA-J scores in the FBG groups, adjusted for age, sex, educational year, smoking status, alcohol consumption, physical activity, body mass index, systolic blood pressure, total cholesterol, and estimated glomerular filtration rate.</p><p><b>Results:</b> The mean MoCA-J score in the total population was 25.0, and the prevalence of MoCA-J score ≤25 was 49.0%. Multivariable-adjusted total MoCA-J scores were 25.2, 24.8, and 23.4 in the normal, IFG, and DM groups, respectively. The odds ratio of MoCA-J score ≤25 in the DM group was 3.29.</p><p><b>Conclusions:</b> FBG level in middle age was negatively associated with total MoCA-J scores assessed later in life, independent of confounding variables.</p>

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  51. Apolipoprotein A2 Isoforms in Relation to the Risk of Myocardial Infarction: A Nested Case-Control Analysis in the JPHC Study. 査読有り 国際誌

    Kihara T, Yamagishi K, Honda K, Ikeda A, Yatsuya H, Saito I, Kokubo Y, Yamaji T, Shimazu T, Sawada N, Iwasaki M, Iso H, Tsugane S, JPHC Study Group.

    Journal of atherosclerosis and thrombosis   28 巻 ( 5 ) 頁: 483 - 490   2021年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  52. Perceptions and behaviors related to noncommunicable diseases in Palau: a qualitative study.

    Shimizu H, Hirakawa Y, Chiang C, Ngiralmau B, Tellei J, Rehuher-Marugg FK, Mita T, Yatsuya H, Aoyama A

    Nagoya journal of medical science   83 巻 ( 2 ) 頁: 287 - 298   2021年5月

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    記述言語:英語   出版者・発行元:Nagoya Journal of Medical Science  

    The increasing burden of noncommunicable diseases (NCDs) is a major public health concern in Palau. This study aims to identify social and psychological factors related to NCDs among Palauan people using a qualitative approach. We conducted eight key informant interviews and eight focus group discussions, which were audio-recorded, transcribed and translated into English. Ideas of the respondents were extracted and labeled, and the labels were analyzed using an inductive multistage approach referred to as qualitative content analysis. Three themes emerged: (1) home education, (2) traditional local community, and (3) modernization and westernization of lifestyle. Respondents believed that the influence of the family on lifestyle was significant, but that disciplining children at home had become difficult. They considered that the traditional lifestyle was mostly healthy, and were reluctant to abandon certain unhealthy customs, such as serving abundant food to guests as a sign of fraternity. They also thought that they overate because of their stressful modernized lifestyle. This is the first qualitative study to analyze perception and behavior of the Palauan people in relation to NCDs. We found that the increase in NCDs was related to two concurrent trends: preserving certain traditional customs unfavorable to good health, and abandoning time-consuming healthy traditional lifestyle to adopt a modernized one. We also found that Palauan people were not confident in their ability to prevent NCDs. Therefore, health promotion activities should be designed to empower people to make positive changes.

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  53. Weight change during middle age and risk of stroke and coronary heart disease: The Japan Public Health Center-based Prospective Study. 国際誌

    Kisanuki K, Muraki I, Yamagishi K, Kokubo Y, Saito I, Yatsuya H, Sawada N, Iso H, Tsugane S, JPHC Study Group.

    Atherosclerosis   322 巻   頁: 67 - 73   2021年4月

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  54. Avoid clinical inertia: Importance of asking and advising patients with diabetes who smoke about quitting. 査読有り

    Yatsuya H

    Journal of diabetes investigation   12 巻 ( 3 ) 頁: 317 - 319   2021年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Diabetes Investigation  

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  55. Factors Associated With Prediabetes and Diabetes Among Public Employees in Northern Ethiopia. 査読有り 国際共著 国際誌

    He Y, Chiang C, Gebremariam LW, Hirakawa Y, Yatsuya H, Aoyama A

    Asia-Pacific journal of public health   33 巻 ( 2-3 ) 頁: 242 - 250   2021年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Asia-Pacific Journal of Public Health  

    The increasing burden of diabetes mellitus is one of the major public health challenges in African countries, including Ethiopia. This is the first study aimed to identify factors associated with prediabetes and diabetes defined by both fasting blood glucose and glycated hemoglobin in Ethiopians. We analyzed data of a cross-sectional survey (1372 adults aged 25-64 years) conducted between October 2015 and February 2016; multinomial logistic regression models were applied. Abdominal obesity, total cholesterol, and non–high-density lipoprotein cholesterol were independently associated with prediabetes and diabetes in both sexes. Increased triglycerides and religious fasting practices were independently associated with prediabetes and diabetes only in men; hypertension was associated with prediabetes and diabetes only in women, while high-density lipoprotein cholesterol was not associated with prediabetes and diabetes in either sex. Sex differences in the association of triglycerides, hypertension, and dietary habit suggest that different approaches of lifestyle modification may be required for men and women.

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  56. Determinants of alcohol consumption and marijuana use among young adults in the Republic of Palau. 査読有り 国際共著

    Sata M, Cui R, Chiang C, Singeo ST Jr, Watson BM, Yatsuya H, Honjo K, Mita T, Temengil EJ, Madraisau S, Yamagishi K, Aoyama A, Iso H

    Environmental health and preventive medicine   26 巻 ( 1 ) 頁: 12   2021年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Environmental Health and Preventive Medicine  

    Background: This study aimed to describe the status of alcohol consumption and drug use among young adults as well as their determinants. Methods: We conducted a cross-sectional study of 356 young adults (aged 18 to 24 years) living in Palau in 2013. The prevalence of self-reported alcohol and marijuana usage were compared within and between sexes, age groups, ethnicities, and education levels. Results: The proportion of current drinking was higher in people aged 21–24 than in those aged 18–20 (73.2% vs. 60.9%, p = 0.09 in men and 48.3% vs. 30.0%, p = 0.02 in women), while that of marijuana use did not differ between the age groups. The proportions of current drinking and marijuana use were higher in Palauan than in other ethnicities (current drinking: 70.6% vs. 40.6%, p = 0.005 in men and 38.8% vs. 16.6%, p = 0.04 in women; lifetime marijuana use: 80.0% vs. 52.9%, p = 0.02 in men and 56.1% vs. 30.6%, p = 0.09 in women). The proportion of frequent (3 times or more) marijuana users was higher for the lower educated than for the higher educated (62.5% vs. 32.1%, p < 0.001 in men and 33.9% vs. 24.4%, p = 0.12 in women). Conclusions: Sex, age, ethnicity, and education were significant determinants of alcohol and marijuana use.

    DOI: 10.1186/s12199-020-00928-8

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  57. Health of university students under job and financial insecurity during COVID-19 pandemic.

    Yatsuya H, Ishitake T

    Journal of occupational health   63 巻 ( 1 ) 頁: e12223   2021年1月

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    記述言語:英語   出版者・発行元:Journal of Occupational Health  

    DOI: 10.1002/1348-9585.12223

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  58. Work-related factors among people with diabetes and the risk of cardiovascular diseases: A systematic review. 査読有り 国際誌

    Saif-Ur-Rahman KM, Mamun R, Li Y, Matsunaga M, Ota A, Yatsuya H

    Journal of occupational health   63 巻 ( 1 ) 頁: e12278   2021年1月

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    担当区分:最終著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Occupational Health  

    Background: Diabetes is a major risk factor for cardiovascular diseases (CVD). This systematic review aims to explore the work-related factors among people with diabetes in developing CVD. Methods: Four electronic databases were searched on 1 February 2021 using a comprehensive search strategy without any time restriction. Two independent researchers screened the articles and extracted data. The risk of bias was assessed independently using the risk of bias assessment tool for non-randomized studies (RoBANS). A narrative synthesis was conducted considering the heterogeneity of the included articles. Results: A total of five articles incorporating 4 409 810 participants from three geographic regions were included that highlights the research gap. As per the included studies, Occupational drivers with diabetes were at a higher risk of CVD in comparison to the nondrivers, workers with diabetes having a long working hour were at a higher risk of CVD mortality, workers with a lower occupational status were at a higher risk of 10-years stroke risk, and occupational physical activity and occupational commuting lowered the risk of CVD deaths. Conclusions: This systematic review summarized the available evidence on work-related factors influencing the risk of CVD in people with diabetes. The findings should be interpreted cautiously pondering the limited evidence and imprecision. We identified only five articles related to the topic, and there were no studies from Japan. The scarcity of studies on work-related factors on the prognosis of diabetic patients implies the need for more research in this field. We recommend further exploration of the topic designing primary studies.

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  59. 一般的な代謝結果を予測するための人工ニューラルネットワークおよびロジスティック回帰の比較(Comparison of artificial neural network and logistic regression for predicting common metabolic outcomes)

    He Yupeng, Chiang Chifa, Hirakawa Yoshihisa, Yatsuya Hiroshi

    Journal of Epidemiology   31 巻 ( Suppl.1 ) 頁: 138 - 138   2021年1月

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    担当区分:最終著者   記述言語:英語   掲載種別:研究論文(その他学術会議資料等)   出版者・発行元:(一社)日本疫学会  

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  60. Global, regional, and national burden of stroke and its risk factors, 1990-2019: A systematic analysis for the Global Burden of Disease Study 2019

    Feigin V.L., Stark B.A., Johnson C.O., Roth G.A., Bisignano C., Abady G.G., Abbasifard M., Abbasi-Kangevari M., Abd-Allah F., Abedi V., Abualhasan A., Abu-Rmeileh N.M.E., Abushouk A.I., Adebayo O.M., Agarwal G., Agasthi P., Ahinkorah B.O., Ahmad S., Ahmadi S., Salih Y.A., Aji B., Akbarpour S., Akinyemi R.O., Al Hamad H., Alahdab F., Alif S.M., Alipour V., Aljunid S.M., Almustanyir S., Al-Raddadi R.M., Salman R.A.S., Alvis-Guzman N., Ancuceanu R., Anderlini D., Anderson J.A., Ansar A., Antonazzo I.C., Arabloo J., Ärnlöv J., Artanti K.D., Aryan Z., Asgari S., Ashraf T., Athar M., Atreya A., Ausloos M., Baig A.A., Baltatu O.C., Banach M., Barboza M.A., Barker-Collo S.L., Bärnighausen T.W., Barone M.T.U., Basu S., Bazmandegan G., Beghi E., Beheshti M., Béjot Y., Bell A.W., Bennett D.A., Bensenor I.M., Bezabhe W.M., Bezabih Y.M., Bhagavathula A.S., Bhardwaj P., Bhattacharyya K., Bijani A., Bikbov B., Birhanu M.M., Boloor A., Bonny A., Brauer M., Brenner H., Bryazka D., Butt Z.A., Dos Santos F.L.C., Campos-Nonato I.R., Cantu-Brito C., Carrero J.J., Castañeda-Orjuela C.A., Catapano A.L., Chakraborty P.A., Charan J., Choudhari S.G., Chowdhury E.K., Chu D.T., Chung S.C., Colozza D., Costa V.M., Costanzo S., Criqui M.H., Dadras O., Dagnew B., Dai X., Dalal K., Damasceno A.A.M., D'Amico E., Dandona L., Dandona R., Gela J.D.

    The Lancet Neurology   20 巻 ( 10 ) 頁: 1 - 26   2021年

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    記述言語:日本語   出版者・発行元:The Lancet Neurology  

    Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]) associated with 19 risk factors, for 204 countries and territories from 1990 to 2019. These estimates were provided for ischaemic stroke, intracerebral haemorrhage, subarachnoid haemorrhage, and all strokes combined, and stratified by sex, age group, and World Bank country income level. Findings In 2019, there were 12·2 million (95% UI 11·0–13·6) incident cases of stroke, 101 million (93·2–111) prevalent cases of stroke, 143 million (133–153) DALYs due to stroke, and 6·55 million (6·00–7·02) deaths from stroke. Globally, stroke remained the second-leading cause of death (11·6% [10·8–12·2] of total deaths) and the third-leading cause of death and disability combined (5·7% [5·1–6·2] of total DALYs) in 2019. From 1990 to 2019, the absolute number of incident strokes increased by 70·0% (67·0–73·0), prevalent strokes increased by 85·0% (83·0–88·0), deaths from stroke increased by 43·0% (31·0–55·0), and DALYs due to stroke increased by 32·0% (22·0–42·0). During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). However, among people younger than 70 years, prevalence rates increased by 22·0% (21·0–24·0) and incidence rates increased by 15·0% (12·0–18·0). In 2019, the age-standardised stroke-related mortality rate was 3·6 (3·5–3·8) times higher in the World Bank low-income group than in the World Bank high-income group, and the age-standardised stroke-related DALY rate was 3·7 (3·5–3·9) times higher in the low-income group than the high-income group. Ischaemic stroke constituted 62·4% of all incident strokes in 2019 (7·63 million [6·57–8·96]), while intracerebral haemorrhage constituted 27·9% (3·41 million [2·97–3·91]) and subarachnoid haemorrhage constituted 9·7% (1·18 million [1·01–1·39]). In 2019, the five leading risk factors for stroke were high systolic blood pressure (contributing to 79·6 million [67·7–90·8] DALYs or 55·5% [48·2–62·0] of total stroke DALYs), high body-mass index (34·9 million [22·3–48·6] DALYs or 24·3% [15·7–33·2]), high fasting plasma glucose (28·9 million [19·8–41·5] DALYs or 20·2% [13·8–29·1]), ambient particulate matter pollution (28·7 million [23·4–33·4] DALYs or 20·1% [16·6–23·0]), and smoking (25·3 million [22·6–28·2] DALYs or 17·6% [16·4–19·0]). Interpretation The annual number of strokes and deaths due to stroke increased substantially from 1990 to 2019, despite substantial reductions in age-standardised rates, particularly among people older than 70 years. The highest age-standardised stroke-related mortality and DALY rates were in the World Bank low-income group. The fastest-growing risk factor for stroke between 1990 and 2019 was high body-mass index. Without urgent implementation of effective primary prevention strategies, the stroke burden will probably continue to grow across the world, particularly in low-income countries.

    DOI: 10.1016/S1474-4422(21)00252-0

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  61. Depressive Tendency and the Risk of Death from Pneumonia: The JACC Study. 査読有り

    Tanabe N, Seki N, Horikawa C, Yatsuya H, Yamagishi K, Iso H, Ukawa S, Tamakoshi A, JACC Study group.

    Internal medicine (Tokyo, Japan)   59 巻 ( 24 ) 頁: 3123 - 3130   2020年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2169/internalmedicine.5052-20

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  62. Pelvic exenteration associated with future renal dysfunction. 査読有り 国際誌

    Sando M, Uehara K, Li Y, Aiba T, Ogura A, Ebata T, Kodera Y, Yatsuya H, Nagino M

    Surgery today   50 巻 ( 12 ) 頁: 1601 - 1609   2020年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Surgery Today  

    Purpose: This study aimed to clarify the long-term change in the renal function after pelvic exenteration (PE) and to evaluate the risk factors for any future dysfunction. Methods: This study comprised 40 patients. A greater than 25% decline in the estimated glomerular filtration rate (eGFR) at 3 years was defined as early renal function disorder (ERFD), possibly predicting future chronic kidney disease (CKD). Results: In the entire cohort, the median eGFR decreased by 23% at 3 years, and CKD developed in 50%. The patients were divided into the ERFD (n = 16) and non-ERFD (n = 24) groups. In the ERFD group, the eGFR significantly decreased by 28% during the first 1.5 years and continued to decline after that, resulting in 81.3% of patients reaching CKD, whereas it was 4% and 37.5%, respectively, in the non-ERFD group. In a growth model analysis, late urinary tract complications (UTC) and small bowel obstruction were shown to be risk factors for ERFD. Conclusion: Although PE was associated with a high incidence of future CKD, ERFD could predict it. Close observation of the eGFR decline over 1.5 years might be beneficial to identify ERFD patients. High-risk patients with late UTC and small bowel obstruction should, therefore, be observed carefully.

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  63. Increased risk of occupational trichloroethylene hypersensitivity syndrome at exposure levels higher than 15 mg/L of urinary trichloroacetic acid, regardless of whether the patients had the HLA-B*13:01 allele. 査読有り 国際共著 国際誌

    Wang H, Nakajima T, Ito Y, Naito H, Zhao N, Li H, Qiu X, Xia L, Chen J, Wu Q, Li L, Huang H, Yanagiba Y, Qu H, Yatsuya H, Kamijima M

    Environmental research   191 巻   頁: 109972 - 109972   2020年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Environmental Research  

    Occupational trichloroethylene (TCE) exposure can cause hypersensitivity syndrome (TCE-HS). The human leukocyte antigen (HLA)-B*13:01 is reportedly an important allele involved in TCE-HS onset. However, the threshold exposure level causing TCE-HS in relation to HLA-B*13:01 remains unknown. We conducted a case-control study comprising 37 TCE-HS patients and 97 age- and sex-matched TCE-tolerant controls from the Han Chinese population. Urine and blood of patients were collected on the first day of hospitalization, and those of controls were collected at the end of their shifts. Urinary trichloroacetic acid (TCA) was measured as an exposure marker, and end-of-shift levels in the patients were estimated using the biological half-life of 83.7 h. HLA-B genotype was identified using DNA from blood. Crude odds ratios (ORs) for TCE-HS in the groups with urinary TCA concentration >15 mg/L to ≤50 mg/L and of >50 mg/L were 21.9 [95% confidence interval (CI) 4.2–114.1] and 27.6 (6.1–125.8), respectively, when the group with urinary TCA ≤15 mg/L was used as a reference. The frequency of HLA-B*13:01, the most common allele in the patients, was 62.2% (23/37), which was significantly higher than 17.5% (17/97) in the TCE-tolerant controls, with a crude OR of 8.4 (3.1–22.6). The mutually-adjusted ORs for urinary TCA >15 to ≤50 mg/L, >50 mg/L, and for HLA-B*13:01 were 33.4 (4.1–270.8), 34.0 (5.3–217.1), and 11.0 (2.4–50.7), respectively. In conclusion, reduction of TCE exposure to ≤15 mg/L is required for TCE-HS prevention because urinary TCA concentration >15 mg/L showed increased risk of TCE-HS, regardless of whether the patients had the HLA-B*13:01 allele.

    DOI: 10.1016/j.envres.2020.109972

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  64. Global Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study

    Roth G.A., Mensah G.A., Johnson C.O., Addolorato G., Ammirati E., Baddour L.M., Barengo N.C., Beaton A., Benjamin E.J., Benziger C.P., Bonny A., Brauer M., Brodmann M., Cahill T.J., Carapetis J.R., Catapano A.L., Chugh S., Cooper L.T., Coresh J., Criqui M.H., DeCleene N.K., Eagle K.A., Emmons-Bell S., Feigin V.L., Fernández-Sola J., Fowkes F.G.R., Gakidou E., Grundy S.M., He F.J., Howard G., Hu F., Inker L., Karthikeyan G., Kassebaum N.J., Koroshetz W.J., Lavie C., Lloyd-Jones D., Lu H.S., Mirijello A., Misganaw A.T., Mokdad A.H., Moran A.E., Muntner P., Narula J., Neal B., Ntsekhe M., Oliveira G.M.M., Otto C.M., Owolabi M.O., Pratt M., Rajagopalan S., Reitsma M.B., Ribeiro A.L.P., Rigotti N.A., Rodgers A., Sable C.A., Shakil S.S., Sliwa K., Stark B.A., Sundström J., Timpel P., Tleyjeh I.I., Valgimigli M., Vos T., Whelton P.K., Yacoub M., Zuhlke L.J., Abbasi-Kangevari M., Abdi A., Abedi A., Aboyans V., Abrha W.A., Abu-Gharbieh E., Abushouk A.I., Acharya D., Adair T., Adebayo O.M., Ademi Z., Advani S.M., Afshari K., Afshin A., Agarwal G., Agasthi P., Ahmad S., Ahmadi S., Ahmed M.B., Aji B., Akalu Y., Akande-Sholabi W., Aklilu A., Akunna C.J., Alahdab F., Al-Eyadhy A., Alhabib K.F., Alif S.M., Alipour V., Aljunid S.M., Alla F., Almasi-Hashiani A., Almustanyir S.

    Journal of the American College of Cardiology   76 巻 ( 25 ) 頁: 2982 - 3021   2020年12月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of the American College of Cardiology  

    Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consistent estimates of population health over time, used all available population-level data sources on incidence, prevalence, case fatality, mortality, and health risks to produce estimates for 204 countries and territories from 1990 to 2019. Prevalent cases of total CVD nearly doubled from 271 million (95% uncertainty interval [UI]: 257 to 285 million) in 1990 to 523 million (95% UI: 497 to 550 million) in 2019, and the number of CVD deaths steadily increased from 12.1 million (95% UI:11.4 to 12.6 million) in 1990, reaching 18.6 million (95% UI: 17.1 to 19.7 million) in 2019. The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. The total number of DALYs due to IHD has risen steadily since 1990, reaching 182 million (95% UI: 170 to 194 million) DALYs, 9.14 million (95% UI: 8.40 to 9.74 million) deaths in the year 2019, and 197 million (95% UI: 178 to 220 million) prevalent cases of IHD in 2019. The total number of DALYs due to stroke has risen steadily since 1990, reaching 143 million (95% UI: 133 to 153 million) DALYs, 6.55 million (95% UI: 6.00 to 7.02 million) deaths in the year 2019, and 101 million (95% UI: 93.2 to 111 million) prevalent cases of stroke in 2019. Cardiovascular diseases remain the leading cause of disease burden in the world. CVD burden continues its decades-long rise for almost all countries outside high-income countries, and alarmingly, the age-standardized rate of CVD has begun to rise in some locations where it was previously declining in high-income countries. There is an urgent need to focus on implementing existing cost-effective policies and interventions if the world is to meet the targets for Sustainable Development Goal 3 and achieve a 30% reduction in premature mortality due to noncommunicable diseases.

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  65. Inherited chromosomally integrated human herpesvirus 6 and autoimmune connective tissue diseases. 査読有り 国際誌

    Kawamura Y, Hashimoto T, Miura H, Kozawa K, Yoshikawa A, Ikeda N, Yatsuya H, Yasuoka H, Yoshikawa T

    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology   132 巻   頁: 104656 - 104656   2020年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  66. Positive Association of Physical Activity with Both Objective and Perceived Measures of the Neighborhood Environment among Older Adults: The Aichi Workers' Cohort Study. 査読有り 国際誌

    Li Y, Yatsuya H, Hanibuchi T, Ota A, Naito H, Otsuka R, Murata C, Hirakawa Y, Chiang C, Uemura M, Tamakoshi K, Aoyama A

    International journal of environmental research and public health   17 巻 ( 21 ) 頁: 1 - 14   2020年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:International Journal of Environmental Research and Public Health  

    We examined the association between objective and perceived neighborhood characteristics and self-reported leisure-time physical activity (PA) in older Japanese residents living in areas ranging from metropolitan to rural in 2016. Objective measures used were walkability and the numbers of parks/green spaces and sports facilities within 500 or 1000 m of subjects’ homes, calculated using geographic information systems. Subjective measures were the subjects’ perceptions of their neighborhoods, assessed using a structured questionnaire. All variables were divided into three groups, and the lowest tertile was used as the reference. We assessed the location and frequency of strolling or brisk walking, moderate-intensity PA, and vigorous-intensity PA (sports) using a self-reported questionnaire and defined as performing a certain type of PA 3–4 times/week as a habit. Living in a neighborhood in the highest tertile for walkability and number of parks/green spaces as well as perception of having good access to recreational facilities, observing others exercising and the presence of walkable sidewalks was associated with walking and sports habits (multivariable odds ratios (ORs): 1.33–2.46, all p < 0.05). Interestingly, objective measures of PA-friendly environmental features were inversely associated with moderate-intensity PA habits, potentially because moderate-intensity PA consisted predominantly of gardening. In conclusion, living in an environment supportive of PA, whether objectively or subjectively measured, is related to leisure-time PA habits among older Japanese adults.

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  67. Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets. 査読有り 国際共著 国際誌

    Matsushita K, Jassal SK, Sang Y, Ballew SH, Grams ME, Surapaneni A, Arnlov J, Bansal N, Bozic M, Brenner H, Brunskill NJ, Chang AR, Chinnadurai R, Cirillo M, Correa A, Ebert N, Eckardt KU, Gansevoort RT, Gutierrez O, Hadaegh F, He J, Hwang SJ, Jafar TH, Kayama T, Kovesdy CP, Landman GW, Levey AS, Lloyd-Jones DM, Major RW, Miura K, Muntner P, Nadkarni GN, Naimark DM, Nowak C, Ohkubo T, Pena MJ, Polkinghorne KR, Sabanayagam C, Sairenchi T, Schneider MP, Shalev V, Shlipak M, Solbu MD, Stempniewicz N, Tollitt J, Valdivielso JM, van der Leeuw J, Wang AY, Wen CP, Woodward M, Yamagishi K, Yatsuya H, Zhang L, Schaeffner E, Coresh J

    EClinicalMedicine   27 巻   頁: 100552 - 100552   2020年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:EClinicalMedicine  

    Background: Chronic kidney disease (CKD) measures (estimated glomerular filtration rate [eGFR] and albuminuria) are frequently assessed in clinical practice and improve the prediction of incident cardiovascular disease (CVD), yet most major clinical guidelines do not have a standardized approach for incorporating these measures into CVD risk prediction. “CKD Patch” is a validated method to calibrate and improve the predicted risk from established equations according to CKD measures. Methods: Utilizing data from 4,143,535 adults from 35 datasets, we developed several “CKD Patches” incorporating eGFR and albuminuria, to enhance prediction of risk of atherosclerotic CVD (ASCVD) by the Pooled Cohort Equation (PCE) and CVD mortality by Systematic COronary Risk Evaluation (SCORE). The risk enhancement by CKD Patch was determined by the deviation between individual CKD measures and the values expected from their traditional CVD risk factors and the hazard ratios for eGFR and albuminuria. We then validated this approach among 4,932,824 adults from 37 independent datasets, comparing the original PCE and SCORE equations (recalibrated in each dataset) to those with addition of CKD Patch. Findings: We confirmed the prediction improvement with the CKD Patch for CVD mortality beyond SCORE and ASCVD beyond PCE in validation datasets (Δc-statistic 0.027 [95% CI 0.018–0.036] and 0.010 [0.007–0.013] and categorical net reclassification improvement 0.080 [0.032–0.127] and 0.056 [0.044–0.067], respectively). The median (IQI) of the ratio of predicted risk for CVD mortality with CKD Patch vs. the original prediction with SCORE was 2.64 (1.89–3.40) in very high-risk CKD (e.g., eGFR 30–44 ml/min/1.73m2 with albuminuria ≥30 mg/g), 1.86 (1.48–2.44) in high-risk CKD (e.g., eGFR 45–59 ml/min/1.73m2 with albuminuria 30–299 mg/g), and 1.37 (1.14–1.69) in moderate risk CKD (e.g., eGFR 60–89 ml/min/1.73m2 with albuminuria 30–299 mg/g), indicating considerable risk underestimation in CKD with SCORE. The corresponding estimates for ASCVD with PCE were 1.55 (1.37–1.81), 1.24 (1.10–1.54), and 1.21 (0.98–1.46). Interpretation: The “CKD Patch” can be used to quantitatively enhance ASCVD and CVD mortality risk prediction equations recommended in major US and European guidelines according to CKD measures, when available. Funding: US National Kidney Foundation and the NIDDK.

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  68. Correction: The Smart Life Stay (SLS) program: effects of a lifestyle intervention program in combination with health tourism and health guidance for type 2 diabetes. 査読有り 国際誌

    Matsushita M, Muramoto A, Nomura E, Eguchi Y, Kato A, Sano Y, Kabayama M, Arakawa M, Oguma Y, Yabe D, Matsunaga M, Yatsuya H, Arima H, Tsushita K

    Nutrition & diabetes   10 巻 ( 1 ) 頁: 34 - 34   2020年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nutrition and Diabetes  

    Following publication, the authors asked to add the following institution to the affiliations of author Madoka Matsushita: Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine Both the PDF and HTML versions of the Article have been updated accordingly.

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  69. Milk Intake and Stroke Mortality in the Japan Collaborative Cohort Study-A Bayesian Survival Analysis. 査読有り 国際共著 国際誌

    Wang C, Yatsuya H, Lin Y, Sasakabe T, Kawai S, Kikuchi S, Iso H, Tamakoshi A

    Nutrients   12 巻 ( 9 )   2020年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/nu12092743

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  70. Risk and population attributable fraction of metabolic syndrome and impaired fasting glucose for the incidence of type 2 diabetes mellitus among middle-aged Japanese individuals: Aichi Worker's Cohort Study. 査読有り

    Kaneko K, Yatsuya H, Li Y, Uemura M, Chiang C, Hirakawa Y, Ota A, Tamakoshi K, Aoyama A

    Journal of diabetes investigation   11 巻 ( 5 ) 頁: 1163 - 1169   2020年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Diabetes Investigation  

    Aims/Introduction: The Japanese government started a nationwide screening program for metabolic syndrome (MetS) to prevent cardiovascular diseases and diabetes in 2008. Although impaired fasting glucose (IFG) is a strong predictor for type 2 diabetes mellitus, the program does not follow up IFG in non-MetS individuals. This study aimed to examine the risk and the population attributable fraction (PAF) of MetS and IFG for incidence of type 2 diabetes mellitus. Materials and Methods: Japanese workers (3,417 men and 714 women) aged 40–64 years without a history of diabetes were prospectively followed. MetS was defined as either abdominal obesity plus two or more metabolic risk factors, or being overweight in the case of normal waist circumference plus three or more metabolic risk factors. IFG was defined as fasting blood glucose 100–125 mg/dL. Results: During a mean 6.3 years, 240 type 2 diabetes mellitus cases were identified. Compared with those without MetS and IFG, the multivariable-adjusted hazard ratios (95% confidence interval) of non-MetS individuals with IFG, MetS individuals without IFG and MetS individuals with IFG for type 2 diabetes mellitus were 4.9 (3.4–7.1), 2.4 (1.6–3.5) and 8.3 (5.9–11.5), respectively. The corresponding PAFs for type 2 diabetes mellitus incidence were 15.6, 9.1 and 29.7%, respectively. Conclusions: IFG represented a higher risk and PAF than MetS for type 2 diabetes mellitus incidence in middle-aged Japanese individuals. The coexistence of MetS and IFG showed the highest risk and PAF for type 2 diabetes mellitus incidence. The current Japanese MetS screening program should be reconsidered to follow up non-MetS individuals with IFG.

    DOI: 10.1111/jdi.13230

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  71. Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17 査読有り 国際共著 国際誌

    Deshpande Aniruddha, Miller-Petrie Molly K., Lindstedt Paulina A., Baumann Mathew M., Johnson Kimberly B., Blacker Brigette F., Abbastabar Hedayat, Abd-Allah Foad, Abdelalim Ahmed, Abdollahpour Ibrahim, Abegaz Kedir Hussein, Abejie Ayenew Negesse, Abreu Lucas Guimaraes, Abrigo Michael R. M., Abualhasan Ahmed, Accrombessi Manfred Mario Kokou, Adamu Abdu A., Adebayo Oladimeji M., Adedeji Isaac Akinkunmi, Adedoyin Rufus Adesoji, Adekanmbi Victor, Adetokunboh Olatunji O., Adhikari Tara Ballav, Afarideh Mohsen, Agudelo-Botero Marcela, Ahmadi Mehdi, Ahmadi Keivan, Ahmed Muktar Beshir, Ahmed Anwar E., Akalu Temesgen Yihunie, Akanda Ali S., Alahdab Fares, Al-Aly Ziyad, Alam Samiah, Alam Noore, Alamene Genet Melak, Alanzi Turki M., Albright James, Albujeer Ammar, Alcalde-Rabanal Jacqueline Elizabeth, Alebel Animut, Alemu Zewdie Aderaw, Ali Muhammad, Alijanzadeh Mehran, Alipour Vahid, Aljunid Syed Mohamed, Almasi Ali, Almasi-Hashiani Amir, Al-Mekhlafi Hesham M., Altirkawi Khalid A., Alvis-Guzman Nelson, Alvis-Zakzuk Nelson J., Amini Saeed, Amit Arianna Maever L., Amul Gianna Gayle Herrera, Andrei Catalina Liliana, Anjomshoa Mina, Ansariadi Ansariadi, Antonio Carl Abelardo T., Antony Benny, Antriyandarti Ernoiz, Arabloo Jalal, Aref Hany Mohamed Amin, Aremu Olatunde, Armoon Bahram, Arora Amit, Aryal Krishna K., Arzani Afsaneh, Asadi-Aliabadi Mehran, Asmelash Daniel, Atalay Hagos Tasew, Athari Seyyede Masoume, Athari Seyyed Shamsadin, Atre Sachin R., Ausloos Marcel, Awasthi Shally, Awoke Nefsu, Quintanilla Beatriz Paulina Ayala, Ayano Getinet, Ayanore Martin Amogre, Aynalem Yared Asmare, Azari Samad, Azman Andrew S., Babaee Ebrahim, Badawi Alaa, Bagherzadeh Mojtaba, Bakkannavar Shankar M., Balakrishnan Senthilkumar, Banach Maciej, Banoub Joseph Adel Mattar, Barac Aleksandra, Barboza Miguel A., Barnighausen Till Winfried, Basu Sanjay, Vo Dinh Bay, Bayati Mohsen, Bedi Neeraj, Beheshti Mahya, Behzadifar Meysam, Behzadifar Masoud, Ramirez Diana Fernanda Bejarano, Bell Michelle L., Bennett Derrick A., Benzian Habib, Berbada Dessalegn Ajema, Bernstein Robert S., Bhat Anusha Ganapati, Bhattacharyya Krittika, Bhaumik Soumyadeep, Bhutta Zulfiqar A., Bijani Ali, Bikbov Boris, Bin Sayeed Muhammad Shahdaat, Biswas Raaj Kishore, Bohlouli Somayeh, Boufous Soufiane, Brady Oliver J., Briko Andrey Nikolaevich, Briko Nikolay Ivanovich, Britton Gabrielle B., Brown Alexandria, Nagaraja Sharath Burugina, Butt Zahid A., Camera Luis Alberto, Campos-Nonato Ismael R., Rincon Julio Cesar Campuzano, Cano Jorge, Car Josip, Cardenas Rosario, Carvalho Felix, Castaneda-Orjuela Carlos A., Castro Franz, Cerin Ester, Chalise Binaya, Chattu Vijay Kumar, Chin Ken Lee, Christopher Devasahayam J., Chu Dinh-Toi, Cormier Natalie Maria, Costa Vera Marisa, Cromwell Elizabeth A., Dadi Abel Fekadu Fekadu, Dahiru Tukur, Dahlawi Saad M. A., Dandona Rakhi, Dandona Lalit, Dang Anh Kim, Daoud Farah, Darwesh Aso Mohammad, Darwish Amira Hamed, Daryani Ahmad, Das Jai K., Das Gupta Rajat, Dash Aditya Prasad, Davila-Cervantes Claudio Alberto, Weaver Nicole Davis, De la Hoz Fernando Pio, De Neve Jan-Walter, Demissie Dereje Bayissa, Demoz Gebre Teklemariam, Denova-Gutierrez Edgar, Deribe Kebede, Desalew Assefa, Dharmaratne Samath Dhamminda, Dhillon Preeti, Dhimal Meghnath, Dhungana Govinda Prasad, Diaz Daniel, Dipeolu Isaac Oluwafemi, Hoa Thi, Dolecek Christiane, Doyle Kerrie E., Dubljanin Eleonora, Duraes Andre Rodrigues, Edinur Hisham Atan, Effiong Andem, Eftekhari Aziz, El Nahas Nevine, Zaki Maysaa El Sayed, El Tantawi Maha, Elhabashy Hala Rashad, El-Jaafary Shaimaa I, El-Khatib Ziad, Elkout Hajer, Elsharkawy Aisha, Enany Shymaa, Endalew Daniel Adane, Eshrati Babak, Eskandarieh Sharareh, Etemadi Arash, Ezekannagha Oluchi, Faraon Emerito Jose A., Fareed Mohammad, Faro Andre, Farzadfar Farshad, Fasil Alebachew Fasil, Fazlzadeh Mehdi, Feigin Valery L., Fekadu Wubalem, Fentahun Netsanet, Fereshtehnejad Seyed-Mohammad, Fernandes Eduarda, Filip Irina, Fischer Florian, Flohr Carsten, Foigt Nataliya A., Folayan Morenike Oluwatoyin, Foroutan Masoud, Franklin Richard Charles, Frostad Joseph Jon, Fukumoto Takeshi, Gad Mohamed M., Garcia Gregory M., Gatotoh Augustine Mwangi, Gayesa Reta Tsegaye, Gebremedhin Ketema Bizuwork, Geramo Yilma Chisha Dea, Gesesew Hailay Abrha, Gezae Kebede Embaye, Ghashghaee Ahmad, Sherbaf Farzaneh Ghazi, Gill Tiffany K., Gill Paramjit Singh, Ginindza Themba G., Girmay Alem, Gizaw Zemichael, Goodridge Amador, Gopalani Sameer Vali, Goulart Barbara Niegia Garcia, Goulart Alessandra C., Grada Ayman, Green Manfred S., Gubari Mohammed Ibrahim Mohialdeen, Gugnani Harish Chander, Guido Davide, Guimaraes Rafael Alves, Guo Yuming, Gupta Rajeev, Gupta Rahul, Ha Giang Hai, Haagsma Juanita A., Hafezi-Nejad Nima, Haile Dessalegn H., Haile Michael Tamene, Hall Brian J., Hamidi Samer, Handiso Demelash Woldeyohannes, Haririan Hamidreza, Hariyani Ninuk, Hasaballah Ahmed I, Hasan Mehedi, Hasanzadeh Amir, Hassen Hamid Yimam, Hayelom Desta Haftu, Hegazy Mohamed I, Heibati Behzad, Heidari Behnam, Hendrie Delia, Henok Andualem, Herteliu Claudiu, Heydarpour Fatemeh, de Hidru Hagos Degefa, Hird Thomas R., Chi Linh Hoang, Hollerich Gillian I, Hoogar Praveen, Hossain Naznin, Hosseinzadeh Mehdi, Househ Mowafa, Hu Guoqing, Humayun Ayesha, Hussain Syed Ather, Hussen Mamusha Aman A., Ibitoye Segun Emmanuel, Ilesanmi Olayinka Stephen, Ilic Milena D., Imani-Nasab Mohammad Hasan, Iqbal Usman, Irvani Seyed Sina Naghibi, Islam Sheikh Mohammed Shariful, Ivers Rebecca Q., Iwu Chinwe Juliana, Jahanmehr Nader, Jakovljevic Mihajlo, Jalali Amir, Jayatilleke Achala Upendra, Jenabi Ensiyeh, Jha Ravi Prakash, Jha Vivekanand, Ji John S., Jonas Jost B., Jozwiak Jacek Jerzy, Kabir Ali, Kabir Zubair, Kanchan Tanuj, Karch Andre, Karki Surendra, Kasaeian Amir, Kasahun Gebremicheal Gebreslassie, Kasaye Habtamu Kebebe, Kassa Gebrehiwot G., Kassa Getachew Mullu, Kayode Gbenga A., Kebede Mihiretu M., Keiyoro Peter Njenga, Ketema Daniel Bekele, Khader Yousef Saleh, Khafaie Morteza Abdullatif, Khalid Nauman, Khalilov Rovshan, Khan Ejaz Ahmad, Khan Junaid, Khan Nuruzzaman, Khatab Khaled, Khater Mona M., Khater Amir M., Khayamzadeh Maryam, Khazaei Mohammad, Khosravi Mohammad Hossein, Khubchandani Jagdish, Kiadaliri Ali, Kim Yun Jin, Kimokoti Ruth W., Kisa Sezer, Kisa Adnan, Kochhar Sonali, Kolola Tufa, Komaki Hamidreza, Kosen Soewarta, Koul Parvaiz A., Koyanagi Ai, Krishan Kewal, Defo Barthelemy Kuate, Kugbey Nuworza, Kumar Pushpendra, Kumar G. Anil, Kumar Manasi, Kusuma Dian, La Vecchia Carlo, Lacey Ben, Lal Aparna, Lal Dharmesh Kumar, Lam Hilton, Lami Faris Hasan, Lansingh Van Charles, Lasrado Savita, Lebedev Georgy, Lee Paul H., LeGrand Kate E., Leili Mostafa, Lenjebo Tsegaye Lolaso, Leshargie Cheru Tesema, Levine Aubrey J., Lewycka Sonia, Li Shanshan, Linn Shai, Liu Shiwei, Lopez Jaifred Christian F., Lopukhov Platon D., Abd El Razek Muhammed Magdy, Prasad D. R. Mahadeshwara, Mahasha Phetole Walter, Mahotra Narayan B., Majeed Azeem, Malekzadeh Reza, Malta Deborah Carvalho, Mamun Abdullah A., Manafi Navid, Mansournia Mohammad Ali, Mapoma Chabila Christopher, Martinez Gabriel, Martini Santi, Martins-Melo Francisco Rogerlandio, Mathur Manu Raj, Mayala Benjamin K., Mazidi Mohsen, McAlinden Colm, Meharie Birhanu Geta, Mehndiratta Man Mohan, Nasab Entezar Mehrabi, Mehta Kala M., Mekonnen Teferi, Mekonnen Tefera Chane, Meles Gebrekiros Gebremichael, Meles Hagazi Gebre, Memiah Peter T. N., Memish Ziad A., Mendoza Walter, Menezes Ritesh G., Mereta Seid Tiku, Meretoja Tuomo J., Mestrovic Tomislav, Metekiya Workua Mekonnen, Miazgowski Bartosz, Miller Ted R., Mini G. K., Mirrakhimov Erkin M., Moazen Babak, Mohajer Bahram, Mohammad Yousef, Mohammad Dara K., Mezerji Naser Mohammad Gholi, Mohammadibakhsh Roghayeh, Mohammed Shafiu, Mohammed Jemal Abdu, Mohammed Hassen, Mohebi Farnam, Mokdad Ali H., Moodley Yoshan, Moradi Masoud, Moradi Ghobad, Moradi-Joo Mohammad, Moraga Paula, Morales Linda, Mosapour Abbas, Mosser Jonathan F., Mouodi Simin, Mousavi Seyyed Meysam, Mozaffor Miliva, Munro Sandra B., Muriithi Moses K., Murray Christopher J. L., Musa Kamarul Imran, Mustafa Ghulam, Muthupandian Saravanan, Naderi Mehdi, Nagarajan Ahamarshan Jayaraman, Naghavi Mohsen, Naik Gurudatta, Nangia Vinay, Nascimento Bruno Ramos, Nazari Javad, Ndwandwe Duduzile Edith, Negoi Ionut, Netsere Henok Biresaw, Ngunjiri Josephine W., Cuong Tat Nguyen, Huong Lan Thi Nguyen, Nguyen QuynhAnh P., Nigatu Solomon Gedlu, Ningrum Dina Nur Anggraini, Nnaji Chukwudi A., Nojomi Marzieh, Norheim Ole F., Noubiap Jean Jacques, Oancea Bogdan, Ogbo Felix Akpojene, Oh In-Hwan, Olagunju Andrew T., Olusanya Jacob Olusegun, Olusanya Bolajoko Olubukunola, Onwujekwe Obinna E., Ortega-Altamirano Doris V, Osarenotor Osayomwanbo, Osei Frank B., Owolabi Mayowa O., Mahesh P. A., Padubidri Jagadish Rao, Pakhale Smita, Pana Adrian, Park Eun-Kee, Patel Sangram Kishor, Pathak Ashish, Patle Ajay, Paulos Kebreab, Pepito Veincent Christian Filipino, Perico Norberto, Pervaiz Aslam, Pescarini Julia Moreira, Pesudovs Konrad, Pham Hai Quang, Pigott David M., Pilgrim Thomas, Pirsaheb Meghdad, Poljak Mario, Pollock Ian, Postma Maarten J., Pourmalek Farshad, Pourshams Akram, Prada Sergio I, Preotescu Liliana, Quintana Hedley, Rabiee Navid, Rabiee Mohammad, Radfar Amir, Rafiei Alireza, Rahim Fakher, Rahimi Siavash, Rahimi-Movaghar Vafa, Rahman Muhammad Aziz, Rahman Mohammad Hifz Ur, Rajati Fatemeh, Ranabhat Chhabi Lal, Rao Puja C., Rasella Davide, Rath Goura Kishor, Rawaf Salman, Rawal Lal, Rawasia Wasiq Faraz, Remuzzi Giuseppe, Renjith Vishnu, Renzaho Andre M. N., Resnikoff Serge, Riahi Seyed Mohammad, Ribeiro Ana Isabel, Rickard Jennifer, Roever Leonardo, Ronfani Luca, Rubagotti Enrico, Rubino Salvatore, Saad Anas M., Sabour Siamak, Sadeghi Ehsan, Moghaddam Sahar Saeedi, Safari Yahya, Sagar Rajesh, Sahraian Mohammad Ali, Sajadi S. Mohammad, Salahshoor Mohammad Reza, Salam Nasir, Saleem Ahsan, Salem Hosni, Salem Marwa Rashad, Salimi Yahya, Salimzadeh Hamideh, Samy Abdallah M., Sanabria Juan, Santos Itamar S., Santric-Milicevic Milena M., Sao Jose Bruno Piassi, Saraswathy Sivan Yegnanarayana Iyer, Sarrafzadegan Nizal, Sartorius Benn, Sathian Brijesh, Sathish Thirunavukkarasu, Satpathy Maheswar, Sawhney Monika, Sayyah Mehdi, Sbarra Alyssa N., Schaeffer Lauren E., Schwebel David C., Senbeta Anbissa Muleta, Senthilkumaran Subramanian, Sepanlou Sadaf G., Servan-Mori Edson, Shafieesabet Azadeh, Shaheen Amira A., Shahid Izza, Shaikh Masood Ali, Shalash Ali S., Shams-Beyranvand Mehran, Shamsi MohammadBagher, Shamsizadeh Morteza, Shannawaz Mohammed, Sharafi Kiomars, Sharma Rajesh, Sheikh Aziz, Shetty B. Suresh Kumar, Shiferaw Wondimeneh Shibabaw, Shigematsu Mika, Shin Jae Il, Shiri Rahman, Shirkoohi Reza, Shivakumar K. M., Si Si, Siabani Soraya, Siddiqi Tariq Jamal, Silva Diego Augusto Santos, Singh Virendra, Singh Narinder Pal, Singh Balbir Bagicha Singh, Singh Jasvinder A., Singh Ambrish, Sinha Dhirendra Narain, Sisay Malede Mequanent, Skiadaresi Eirini, Smith David L., Filho Adauto Martins Soares, Sobhiyeh Mohammad Reza, Sokhan Anton, Soriano Joan B., Sorrie Muluken Bekele, Soyiri Ireneous N., Spurlock Emma Elizabeth, Sreeramareddy Chandrashekhar T., Sudaryanto Agus, Sufiyan Mu'awiyyah Babale, Suleria Hafiz Ansar Rasul, Sykes Bryan L., Tabares-Seisdedos Rafael, Tabuchi Takahiro, Tadesse Degena Bahrey, Tarigan Ingan Ukur, Taye Bineyam, Tefera Yonatal Mesfin, Tehrani-Banihashemi Arash, Tekelemedhin Shishay Wahdey, Tekle Merhawi Gebremedhin, Temsah Mohamad-Hani, Tesfay Berhe Etsay, Tesfay Fisaha Haile, Tessema Zemenu Tadesse, Thankappan Kavumpurathu Raman, ThekkePurakkal Akhil Soman, Thomas Nihal, Thompson Robert L., Thomson Alan J., Topor-Madry Roman, Tovani-Palone Marcos Roberto, Traini Eugenio, Bach Xuan Tran, Khanh Bao Tran, Ullah Irfan, Unnikrishnan Bhaskaran, Usman Muhammad Shariq, Uthman Olalekan A., Uzochukwu Benjamin S. Chudi, Valdez Pascual R., Varughese Santosh, Veisani Yousef, Violante Francesco S., Vollmer Sebastian, Whawariat Feleke Gebremeskel, Waheed Yasir, Wallin Mitchell Taylor, Wang Yuan-Pang, Wang Yafeng, Wangdi Kinley, Weiss Daniel J., Weldesamuel Girmay Teklay, Werkneh Adhena Ayaliew, Westerman Ronny, Wiangkham Taweewat, Wiens Kirsten E., Wijeratne Tissa, Wiysonge Charles Shey, Wolde Haileab Fekadu, Wondafrash Dawit Zewdu, Wonde Tewodros Eshete, Worku Getasew Taddesse, Yadollahpour Ali, Jabbari Seyed Hossein Yahyazadeh, Yamada Tomohide, Yaseri Mehdi, Yatsuya Hiroshi, Yeshaneh Alex, Yilma Mekdes Tigistu, Yip Paul, Yisma Engida, Yonemoto Naohiro, Younis Mustafa Z., Yousof Hebat-Allah Salah A., Yu Chuanhua, Yusefzadeh Hasan, Zadey Siddhesh, Moghadam Telma Zahirian, Zaidi Zoubida, Bin Zaman Sojib, Zamani Mohammad, Zandian Hamed, Zar Heather J., Zerfu Taddese Alemu, Zhang Yunquan, Ziapour Arash, Zodpey Sanjay, Zuniga Yves Miel H., Hay Simon I, Reiner Robert C. Jr.

    LANCET GLOBAL HEALTH   8 巻 ( 9 ) 頁: E1162 - E1185   2020年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  72. Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17

    Deshpande A., Miller-Petrie M.K., Lindstedt P.A., Baumann M.M., Johnson K.B., Blacker B.F., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahpour I., Abegaz K.H., Abejie A.N., Abreu L.G., Abrigo M.R.M., Abualhasan A., Accrombessi M.M.K., Adamu A.A., Adebayo O.M., Adedeji I.A., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhikari T.B., Afarideh M., Agudelo-Botero M., Ahmadi M., Ahmadi K., Ahmed A.E., Ahmed M.B., Akalu T.Y., Akanda A.S., Alahdab F., Al-Aly Z., Alam N., Alam S., Alamene G.M., Alanzi T.M., Albright J., Albujeer A., Alcalde-Rabanal J.E., Alebel A., Alemu Z.A., Ali M., Alijanzadeh M., Alipour V., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Alvis-Guzman N., Alvis-Zakzuk N.J., Amini S., Amit A.M.L., Amul G.G.H., Andrei C.L., Anjomshoa M., Ansariadi A., Antonio C.A.T., Antony B., Antriyandarti E., Arabloo J., Aref H.M.A., Aremu O., Armoon B., Arora A., Aryal K.K., Arzani A., Asadi-Aliabadi M., Asmelash D., Atalay H.T., Athari S.S., Athari S.M., Atre S.R., Ausloos M., Awasthi S., Awoke N., Quintanilla B.P.A., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azman A.S., Babaee E., Badawi A., Bagherzadeh M., Bakkannavar S.M., Balakrishnan S., Banach M., Banoub J.A.M., Barac A., Barboza M.A., Bärnighausen T.W., Basu S., Bay V.D., Bayati M., Bedi N., Beheshti M., Behzadifar M., Behzadifar M.

    The Lancet Global Health   8 巻 ( 9 ) 頁: e1162 - e1185   2020年9月

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    記述言語:日本語   出版者・発行元:The Lancet Global Health  

    Background: Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinking water and sanitation facilities. Methods: We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and aggregated results to policy-relevant administrative units. We estimated mutually exclusive and collectively exhaustive subcategories of facilities for drinking water (piped water on or off premises, other improved facilities, unimproved, and surface water) and sanitation facilities (septic or sewer sanitation, other improved, unimproved, and open defecation) with use of ordinal regression. We also estimated the number of diarrhoeal deaths in children younger than 5 years attributed to unsafe facilities and estimated deaths that were averted by increased access to safe facilities in 2017, and analysed geographical inequality in access within LMICs. Findings: Across LMICs, access to both piped water and improved water overall increased between 2000 and 2017, with progress varying spatially. For piped water, the safest water facility type, access increased from 40·0% (95% uncertainty interval [UI] 39·4–40·7) to 50·3% (50·0–50·5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. Access to both sewer or septic sanitation and improved sanitation overall also increased across all LMICs during the study period. For sewer or septic sanitation, access was 46·3% (95% UI 46·1–46·5) in 2017, compared with 28·7% (28·5–29·0) in 2000. Although some units improved access to the safest drinking water or sanitation facilities since 2000, a large absolute number of people continued to not have access in several units with high access to such facilities (>80%) in 2017. More than 253 000 people did not have access to sewer or septic sanitation facilities in the city of Harare, Zimbabwe, despite 88·6% (95% UI 87·2–89·7) access overall. Many units were able to transition from the least safe facilities in 2000 to safe facilities by 2017; for units in which populations primarily practised open defecation in 2000, 686 (95% UI 664–711) of the 1830 (1797–1863) units transitioned to the use of improved sanitation. Geographical disparities in access to improved water across units decreased in 76·1% (95% UI 71·6–80·7) of countries from 2000 to 2017, and in 53·9% (50·6–59·6) of countries for access to improved sanitation, but remained evident subnationally in most countries in 2017. Interpretation: Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation. Funding: Bill & Melinda Gates Foundation.

    DOI: 10.1016/S2214-109X(20)30278-3

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  73. Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17

    Aniruddha Deshpande, Molly K. Miller-Petrie, Paulina A. Lindstedt, Mathew M. Baumann, Kimberly B. Johnson, Brigette F. Blacker, Hedayat Abbastabar, Foad Abd-Allah, Ahmed Abdelalim, Ibrahim Abdollahpour, Kedir Hussein Abegaz, Ayenew Negesse Abejie, Lucas Guimaraes Abreu, Michael R. M. Abrigo, Ahmed Abualhasan, Manfred Mario Kokou Accrombessi, Abdu A. Adamu, Oladimeji M. Adebayo, Isaac Akinkunmi Adedeji, Rufus Adesoji Adedoyin, Victor Adekanmbi, Olatunji O. Adetokunboh, Tara Ballav Adhikari, Mohsen Afarideh, Marcela Agudelo-Botero, Mehdi Ahmadi, Keivan Ahmadi, Muktar Beshir Ahmed, Anwar E. Ahmed, Temesgen Yihunie Akalu, Ali S. Akanda, Fares Alahdab, Ziyad Al-Aly, Samiah Alam, Noore Alam, Genet Melak Alamene, Turki M. Alanzi, James Albright, Ammar Albujeer, Jacqueline Elizabeth Alcalde-Rabanal, Animut Alebel, Zewdie Aderaw Alemu, Muhammad Ali, Mehran Alijanzadeh, Vahid Alipour, Syed Mohamed Aljunid, Ali Almasi, Amir Almasi-Hashiani, Hesham M. Al-Mekhlafi, Khalid A. Altirkawi, Nelson Alvis-Guzman, Nelson J. Alvis-Zakzuk, Saeed Amini, Arianna Maever L. Amit, Gianna Gayle Herrera Amul, Catalina Liliana Andrei, Mina Anjomshoa, Ansariadi Ansariadi, Carl Abelardo T. Antonio, Benny Antony, Ernoiz Antriyandarti, Jalal Arabloo, Hany Mohamed Amin Aref, Olatunde Aremu, Bahram Armoon, Amit Arora, Krishna K. Aryal, Afsaneh Arzani, Mehran Asadi-Aliabadi, Daniel Asmelash, Hagos Tasew Atalay, Seyyede Masoume Athari, Seyyed Shamsadin Athari, Sachin R. Atre, Marcel Ausloos, Shally Awasthi, Nefsu Awoke, Beatriz Paulina Ayala Quintanilla, Getinet Ayano, Martin Amogre Ayanore, Yared Asmare Aynalem, Samad Azari, Andrew S. Azman, Ebrahim Babaee, Alaa Badawi, Mojtaba Bagherzadeh, Shankar M. Bakkannavar, Senthilkumar Balakrishnan, Maciej Banach, Joseph Adel Mattar Banoub, Aleksandra Barac, Miguel A. Barboza, Till Winfried Barnighausen, Sanjay Basu, Vo Dinh Bay, Mohsen Bayati, Neeraj Bedi, Mahya Beheshti, Meysam Behzadifar, Masoud Behzadifar, Diana Fernanda Bejarano Ramirez, Michelle L. Bell, Derrick A. Bennett, Habib Benzian, Dessalegn Ajema Berbada, Robert S. Bernstein, Anusha Ganapati Bhat, Krittika Bhattacharyya, Soumyadeep Bhaumik, Zulfiqar A. Bhutta, Ali Bijani, Boris Bikbov, Muhammad Shahdaat Bin Sayeed, Raaj Kishore Biswas, Somayeh Bohlouli, Soufiane Boufous, Oliver J. Brady, Andrey Nikolaevich Briko, Nikolay Ivanovich Briko, Gabrielle B. Britton, Alexandria Brown, Sharath Burugina Nagaraja, Zahid A. Butt, Luis Alberto Camera, Ismael R. Campos-Nonato, Julio Cesar Campuzano Rincon, Jorge Cano, Josip Car, Rosario Cardenas, Felix Carvalho, Carlos A. Castaneda-Orjuela, Franz Castro, Ester Cerin, Binaya Chalise, Vijay Kumar Chattu, Ken Lee Chin, Devasahayam J. Christopher, Dinh-Toi Chu, Natalie Maria Cormier, Vera Marisa Costa, Elizabeth A. Cromwell, Abel Fekadu Fekadu Dadi, Tukur Dahiru, Saad M. A. Dahlawi, Rakhi Dandona, Lalit Dandona, Anh Kim Dang, Farah Daoud, Aso Mohammad Darwesh, Amira Hamed Darwish, Ahmad Daryani, Jai K. Das, Rajat Das Gupta, Aditya Prasad Dash, Claudio Alberto Davila-Cervantes, Nicole Davis Weaver, Fernando Pio De la Hoz, Jan-Walter De Neve, Dereje Bayissa Demissie, Gebre Teklemariam Demoz, Edgar Denova-Gutierrez, Kebede Deribe, Assefa Desalew, Samath Dhamminda Dharmaratne, Preeti Dhillon, Meghnath Dhimal, Govinda Prasad Dhungana, Daniel Diaz, Isaac Oluwafemi Dipeolu, Hoa Thi, Christiane Dolecek, Kerrie E. Doyle, Eleonora Dubljanin, Andre Rodrigues Duraes, Hisham Atan Edinur, Andem Effiong, Aziz Eftekhari, Nevine El Nahas, Maysaa El Sayed Zaki, Maha El Tantawi, Hala Rashad Elhabashy, Shaimaa El-Jaafary, Ziad El-Khatib, Hajer Elkout, Aisha Elsharkawy, Shymaa Enany, Daniel Adane Endalew, Babak Eshrati, Sharareh Eskandarieh, Arash Etemadi, Oluchi Ezekannagha, Emerito Jose A. Faraon, Mohammad Fareed, Andre Faro, Farshad Farzadfar, Alebachew Fasil Fasil, Mehdi Fazlzadeh, Valery L. Feigin, Wubalem Fekadu, Netsanet Fentahun, Seyed-Mohammad Fereshtehnejad, Eduarda Fernandes, Irina Filip, Florian Fischer, Carsten Flohr, Nataliya A. Foigt, Morenike Oluwatoyin Folayan, Masoud Foroutan, Richard Charles Franklin, Joseph Jon Frostad, Takeshi Fukumoto, Mohamed M. Gad, Gregory M. Garcia, Augustine Mwangi Gatotoh, Reta Tsegaye Gayesa, Ketema Bizuwork Gebremedhin, Yilma Chisha Dea Geramo, Hailay Abrha Gesesew, Kebede Embaye Gezae, Ahmad Ghashghaee, Farzaneh Ghazi Sherbaf, Tiffany K. Gill, Paramjit Singh Gill, Themba G. Ginindza, Alem Girmay, Zemichael Gizaw, Amador Goodridge, Sameer Vali Gopalani, Barbara Niegia Garcia Goulart, Alessandra C. Goulart, Ayman Grada, Manfred S. Green, Mohammed Ibrahim Mohialdeen Gubari, Harish Chander Gugnani, Davide Guido, Rafael Alves Guimaraes, Yuming Guo, Rajeev Gupta, Rahul Gupta, Giang Hai Ha, Juanita A. Haagsma, Nima Hafezi-Nejad, Dessalegn H. Haile, Michael Tamene Haile, Brian J. Hall, Samer Hamidi, Demelash Woldeyohannes Handiso, Hamidreza Haririan, Ninuk Hariyani, Ahmed Hasaballah, Mehedi Hasan, Amir Hasanzadeh, Hamid Yimam Hassen, Desta Haftu Hayelom, Mohamed Hegazy, Behzad Heibati, Behnam Heidari, Delia Hendrie, Andualem Henok, Claudiu Herteliu, Fatemeh Heydarpour, Hagos Degefa de Hidru, Thomas R. Hird, Chi Linh Hoang, Gillian Hollerich, Praveen Hoogar, Naznin Hossain, Mehdi Hosseinzadeh, Mowafa Househ, Guoqing Hu, Ayesha Humayun, Syed Ather Hussain, Mamusha Aman A. Hussen, Segun Emmanuel Ibitoye, Olayinka Stephen Ilesanmi, Milena D. Ilic, Mohammad Hasan Imani-Nasab, Usman Iqbal, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam, Rebecca Q. Ivers, Chinwe Juliana Iwu, Nader Jahanmehr, Mihajlo Jakovljevic, Amir Jalali, Achala Upendra Jayatilleke, Ensiyeh Jenabi, Ravi Prakash Jha, Vivekanand Jha, John S. Ji, Jost B. Jonas, Jacek Jerzy Jozwiak, Ali Kabir, Zubair Kabir, Tanuj Kanchan, Andre Karch, Surendra Karki, Amir Kasaeian, Gebremicheal Gebreslassie Kasahun, Habtamu Kebebe Kasaye, Gebrehiwot G. Kassa, Getachew Mullu Kassa, Gbenga A. Kayode, Mihiretu M. Kebede, Peter Njenga Keiyoro, Daniel Bekele Ketema, Yousef Saleh Khader, Morteza Abdullatif Khafaie, Nauman Khalid, Rovshan Khalilov, Ejaz Ahmad Khan, Junaid Khan, Nuruzzaman Khan, Khaled Khatab, Mona M. Khater, Amir M. Khater, Maryam Khayamzadeh, Mohammad Khazaei, Mohammad Hossein Khosravi, Jagdish Khubchandani, Ali Kiadaliri, Yun Jin Kim, Ruth W. Kimokoti, Sezer Kisa, Adnan Kisa, Sonali Kochhar, Tufa Kolola, Hamidreza Komaki, Soewarta Kosen, Parvaiz A. Koul, Ai Koyanagi, Kewal Krishan, Barthelemy Kuate Defo, Nuworza Kugbey, Pushpendra Kumar, G. Anil Kumar, Manasi Kumar, Dian Kusuma, Carlo La Vecchia, Ben Lacey, Aparna Lal, Dharmesh Kumar Lal, Hilton Lam, Faris Hasan Lami, Van Charles Lansingh, Savita Lasrado, Georgy Lebedev, Paul H. Lee, Kate E. LeGrand, Mostafa Leili, Tsegaye Lolaso Lenjebo, Cheru Tesema Leshargie, Aubrey J. Levine, Sonia Lewycka, Shanshan Li, Shai Linn, Shiwei Liu, Jaifred Christian F. Lopez, Platon D. Lopukhov, Muhammed Magdy Abd El Razek, D. R. Mahadeshwara Prasad, Phetole Walter Mahasha, Narayan B. Mahotra, Azeem Majeed, Reza Malekzadeh, Deborah Carvalho Malta, Abdullah A. Mamun, Navid Manafi, Mohammad Ali Mansournia, Chabila Christopher Mapoma, Gabriel Martinez, Santi Martini, Francisco Rogerlandio Martins-Melo, Manu Raj Mathur, Benjamin K. Mayala, Mohsen Mazidi, Colm McAlinden, Birhanu Geta Meharie, Man Mohan Mehndiratta, Entezar Mehrabi Nasab, Kala M. Mehta, Teferi Mekonnen, Tefera Chane Mekonnen, Gebrekiros Gebremichael Meles, Hagazi Gebre Meles, Peter T. N. Memiah, Ziad A. Memish, Walter Mendoza, Ritesh G. Menezes, Seid Tiku Mereta, Tuomo J. Meretoja, Tomislav Mestrovic, Workua Mekonnen Metekiya, Bartosz Miazgowski, Ted R. Miller, G. K. Mini, Erkin M. Mirrakhimov, Babak Moazen, Bahram Mohajer, Yousef Mohammad, Dara K. Mohammad, Naser Mohammad Gholi Mezerji, Roghayeh Mohammadibakhsh, Shafiu Mohammed, Jemal Abdu Mohammed, Hassen Mohammed, Farnam Mohebi, Ali H. Mokdad, Yoshan Moodley, Masoud Moradi, Ghobad Moradi, Mohammad Moradi-Joo, Paula Moraga, Linda Morales, Abbas Mosapour, Jonathan F. Mosser, Simin Mouodi, Seyyed Meysam Mousavi, Miliva Mozaffor, Sandra B. Munro, Moses K. Muriithi, Christopher J. L. Murray, Kamarul Imran Musa, Ghulam Mustafa, Saravanan Muthupandian, Mehdi Naderi, Ahamarshan Jayaraman Nagarajan, Mohsen Naghavi, Gurudatta Naik, Vinay Nangia, Bruno Ramos Nascimento, Javad Nazari, Duduzile Edith Ndwandwe, Ionut Negoi, Henok Biresaw Netsere, Josephine W. Ngunjiri, Cuong Tat Nguyen, Huong Lan Thi Nguyen, QuynhAnh P. Nguyen, Solomon Gedlu Nigatu, Dina Nur Anggraini Ningrum, Chukwudi A. Nnaji, Marzieh Nojomi, Ole F. Norheim, Jean Jacques Noubiap, Bogdan Oancea, Felix Akpojene Ogbo, In-Hwan Oh, Andrew T. Olagunju, Jacob Olusegun Olusanya, Bolajoko Olubukunola Olusanya, Obinna E. Onwujekwe, Doris Ortega-Altamirano, Osayomwanbo Osarenotor, Frank B. Osei, Mayowa O. Owolabi, P. A. Mahesh, Jagadish Rao Padubidri, Smita Pakhale, Adrian Pana, Eun-Kee Park, Sangram Kishor Patel, Ashish Pathak, Ajay Patle, Kebreab Paulos, Veincent Christian Filipino Pepito, Norberto Perico, Aslam Pervaiz, Julia Moreira Pescarini, Konrad Pesudovs, Hai Quang Pham, David M. Pigott, Thomas Pilgrim, Meghdad Pirsaheb, Mario Poljak, Ian Pollock, Maarten J. Postma, Farshad Pourmalek, Akram Pourshams, Sergio Prada, Liliana Preotescu, Hedley Quintana, Navid Rabiee, Mohammad Rabiee, Amir Radfar, Alireza Rafiei, Fakher Rahim, Siavash Rahimi, Vafa Rahimi-Movaghar, Muhammad Aziz Rahman, Mohammad Hifz Ur Rahman, Fatemeh Rajati, Chhabi Lal Ranabhat, Puja C. Rao, Davide Rasella, Goura Kishor Rath, Salman Rawaf, Lal Rawal, Wasiq Faraz Rawasia, Giuseppe Remuzzi, Vishnu Renjith, Andre M. N. Renzaho, Serge Resnikoff, Seyed Mohammad Riahi, Ana Isabel Ribeiro, Jennifer Rickard, Leonardo Roever, Luca Ronfani, Enrico Rubagotti, Salvatore Rubino, Anas M. Saad, Siamak Sabour, Ehsan Sadeghi, Sahar Saeedi Moghaddam, Yahya Safari, Rajesh Sagar, Mohammad Ali Sahraian, S. Mohammad Sajadi, Mohammad Reza Salahshoor, Nasir Salam, Ahsan Saleem, Hosni Salem, Marwa Rashad Salem, Yahya Salimi, Hamideh Salimzadeh, Abdallah M. Samy, Juan Sanabria, Itamar S. Santos, Milena M. Santric-Milicevic, Bruno Piassi Sao Jose, Sivan Yegnanarayana Iyer Saraswathy, Nizal Sarrafzadegan, Benn Sartorius, Brijesh Sathian, Thirunavukkarasu Sathish, Maheswar Satpathy, Monika Sawhney, Mehdi Sayyah, Alyssa N. Sbarra, Lauren E. Schaeffer, David C. Schwebel, Anbissa Muleta Senbeta, Subramanian Senthilkumaran, Sadaf G. Sepanlou, Edson Servan-Mori, Azadeh Shafieesabet, Amira A. Shaheen, Izza Shahid, Masood Ali Shaikh, Ali S. Shalash, Mehran Shams-Beyranvand, MohammadBagher Shamsi, Morteza Shamsizadeh, Mohammed Shannawaz, Kiomars Sharafi, Rajesh Sharma, Aziz Sheikh, B. Suresh Kumar Shetty, Wondimeneh Shibabaw Shiferaw, Mika Shigematsu, Jae Il Shin, Rahman Shiri, Reza Shirkoohi, K. M. Shivakumar, Si Si, Soraya Siabani, Tariq Jamal Siddiqi, Diego Augusto Santos Silva, Virendra Singh, Narinder Pal Singh, Balbir Bagicha Singh Singh, Jasvinder A. Singh, Ambrish Singh, Dhirendra Narain Sinha, Malede Mequanent Sisay, Eirini Skiadaresi, David L. Smith, Adauto Martins Soares Filho, Mohammad Reza Sobhiyeh, Anton Sokhan, Joan B. Soriano, Muluken Bekele Sorrie, Ireneous N. Soyiri, Emma Elizabeth Spurlock, Chandrashekhar T. Sreeramareddy, Agus Sudaryanto, Mu'awiyyah Babale Sufiyan, Hafiz Ansar Rasul Suleria, Bryan L. Sykes, Rafael Tabares-Seisdedos, Takahiro Tabuchi, Degena Bahrey Tadesse, Ingan Ukur Tarigan, Bineyam Taye, Yonatal Mesfin Tefera, Arash Tehrani-Banihashemi, Shishay Wahdey Tekelemedhin, Merhawi Gebremedhin Tekle, Mohamad-Hani Temsah, Berhe Etsay Tesfay, Fisaha Haile Tesfay, Zemenu Tadesse Tessema, Kavumpurathu Raman Thankappan, Akhil Soman ThekkePurakkal, Nihal Thomas, Robert L. Thompson, Alan J. Thomson, Roman Topor-Madry, Marcos Roberto Tovani-Palone, Eugenio Traini, Bach Xuan Tran, Khanh Bao Tran, Irfan Ullah, Bhaskaran Unnikrishnan, Muhammad Shariq Usman, Olalekan A. Uthman, Benjamin S. Chudi Uzochukwu, Pascual R. Valdez, Santosh Varughese, Yousef Veisani, Francesco S. Violante, Sebastian Vollmer, Feleke Gebremeskel Whawariat, Yasir Waheed, Mitchell Taylor Wallin, Yuan-Pang Wang, Yafeng Wang, Kinley Wangdi, Daniel J. Weiss, Girmay Teklay Weldesamuel, Adhena Ayaliew Werkneh, Ronny Westerman, Taweewat Wiangkham, Kirsten E. Wiens, Tissa Wijeratne, Charles Shey Wiysonge, Haileab Fekadu Wolde, Dawit Zewdu Wondafrash, Tewodros Eshete Wonde, Getasew Taddesse Worku, Ali Yadollahpour, Seyed Hossein Yahyazadeh Jabbari, Tomohide Yamada, Mehdi Yaseri, Hiroshi Yatsuya, Alex Yeshaneh, Mekdes Tigistu Yilma, Paul Yip, Engida Yisma, Naohiro Yonemoto, Mustafa Z. Younis, Hebat-Allah Salah A. Yousof, Chuanhua Yu, Hasan Yusefzadeh, Siddhesh Zadey, Telma Zahirian Moghadam, Zoubida Zaidi, Sojib Bin Zaman, Mohammad Zamani, Hamed Zandian, Heather J. Zar, Taddese Alemu Zerfu, Yunquan Zhang, Arash Ziapour, Sanjay Zodpey, Yves Miel H. Zuniga, Simon Hay, Robert C. Reiner

    LANCET GLOBAL HEALTH   8 巻 ( 9 ) 頁: E1162 - E1185   2020年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCI LTD  

    Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinking water and sanitation facilities.Methods We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and aggregated results to policy-relevant administrative units. We estimated mutually exclusive and collectively exhaustive subcategories of facilities for drinking water (piped water on or off premises, other improved facilities, unimproved, and surface water) and sanitation facilities (septic or sewer sanitation, other improved, unimproved, and open defecation) with use of ordinal regression. We also estimated the number of diarrhoeal deaths in children younger than 5 years attributed to unsafe facilities and estimated deaths that were averted by increased access to safe facilities in 2017, and analysed geographical inequality in access within LMICs.Findings Across LMICs, access to both piped water and improved water overall increased between 2000 and 2017, with progress varying spatially. For piped water, the safest water facility type, access increased from 40.0% (95% uncertainty interval [UI] 39.4-40.7) to 50.3% (50.0-50.5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. Access to both sewer or septic sanitation and improved sanitation overall also increased across all LMICs during the study period. For sewer or septic sanitation, access was 46.3% (95% UI 46.1-46.5) in 2017, compared with 28.7% (28.5-29.0) in 2000. Although some units improved access to the safest drinking water or sanitation facilities since 2000, a large absolute number of people continued to not have access in several units with high access to such facilities (>80%) in 2017. More than 253 000 people did not have access to sewer or septic sanitation facilities in the city of Harare, Zimbabwe, despite 88.6% (95% UI 87.2-89.7) access overall. Many units were able to transition from the least safe facilities in 2000 to safe facilities by 2017; for units in which populations primarily practised open defecation in 2000, 686 (95% UI 664-711) of the 1830 (1797-1863) units transitioned to the use of improved sanitation. Geographical disparities in access to improved water across units decreased in 76.1% (95% UI 71.6-80.7) of countries from 2000 to 2017, and in 53.9% (50.6-59.6) of countries for access to improved sanitation, but remained evident subnationally in most countries in 2017.Interpretation Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.

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  74. The Smart Life Stay (SLS) program: effects of a lifestyle intervention program in combination with health tourism and health guidance for type 2 diabetes. 査読有り 国際誌

    Matsushita M, Muramoto A, Nomura E, Eguchi Y, Kato A, Sano Y, Kabayama M, Arakawa M, Oguma Y, Yabe D, Matsunaga M, Yatsuya H, Arima H, Tsushita K

    Nutrition & diabetes   10 巻 ( 1 ) 頁: 33 - 33   2020年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nutrition and Diabetes  

    Background: The aim of this study was to determine the effectiveness of the Smart Life Stay (SLS) program, which is an experience-oriented stayover program, in combination with health tourism and mandatory health guidance on glucose metabolism after 2 years. Methods: The participants of the SLS program (n = 792) were recruited from a database of 23 medical insurers. They underwent a mandatory health examination termed Specific Health Checkups in 2014. The participants were included if they had diabetes or were at a high risk of diabetes and if they satisfied the following inclusion criteria: (1) body mass index (BMI; kg/m2) > 25, or (2) waist circumference (WC; cm) > 85 for men and > 90 for women, or (3) hemoglobin A1c (HbA1c; %) > 5.6, or (4) fasting plasma glucose (FPG; mg/dl) > 100. Individuals who corresponded to one or more items were included as study participants. The control subjects (n = 3645) were nonparticipants of the program who were selected from the database and met the inclusion criteria. The lifestyle changes and changes in mean BMI, WC, FPG, and HbA1c in both groups from baseline to 2-year follow-up were compared by inverse probability weighting of a propensity score. Results: The percentage of people who exercised regularly increased significantly in the SLS group compared with the control group. In the SLS group, BW, BMI, and WC significantly decreased by 1.75 kg, 0.60 kg/m2, and 1.45 cm, respectively, whereas in the control group, WC, FPG, and HbA1c increased significantly by 0.38 cm, 3.37 mg/dl, and 0.12%, respectively. The comparison between groups revealed that the BW, BMI, WC, FPG, and HbA1c improved significantly in the SLS group. Conclusions: The SLS program is suggested to help improve glucose metabolism. This program could be a feasible option as a lifestyle intervention program for diabetes.

    DOI: 10.1038/s41387-020-00136-x

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  75. Glycated haemoglobin (HbA1c) as a reliable option for detecting diabetes among the urban poor population in Bangladesh. 査読有り 国際共著 国際誌

    Chiang C, Aoyama A, Khalequzzaman M, Choudhury SR, Paul D, Rayna SE, Khan FA, Hirakawa Y, Iso H, Yatsuya H

    European journal of public health   30 巻 ( 4 ) 頁: 839 - 841   2020年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:European Journal of Public Health  

    Our previous epidemiological survey targeting urban slum dwellers in Bangladesh showed that the prevalence of diabetes defined by glycated haemoglobin (HbA1c) was higher than the national estimation, and higher in women than men. Subsequently, we conducted the oral glucose tolerance test (OGTT) and found that HbA1c values were consistent with the OGTT findings for detecting diabetes. Our findings indicated that HbA1c ≥6.5% was a rational cut-off, but the optimal HbA1c cut-off for this population might be lower than the internationally recommended threshold. Measuring HbA1c would be a reliable and feasible option for detecting diabetes among underprivileged population in developing countries.

    DOI: 10.1093/eurpub/cky275

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  76. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17 査読有り 国際共著 国際誌

    Wiens Kirsten E., Lindstedt Paulina A., Blacker Brigette F., Johnson Kimberly B., Baumann Mathew M., Schaeffer Lauren E., Abbastabar Hedayat, Abd-Allah Foad, Abdelalim Ahmed, Abdollahpour Ibrahim, Abegaz Kedir Hussein, Abejie Ayenew Negesse, Abreu Lucas Guimaraes, Abrigo Michael R. M., Abualhasan Ahmed, Accrombessi Manfred Mario Kokou, Acharya Dilaram, Adabi Maryam, Adamu Abdu A., Adebayo Oladimeji M., Adedoyin Rufus Adesoji, Adekanmbi Victor, Adetokunboh Olatunji O., Adhena Beyene Meressa, Afarideh Mohsen, Ahmad Sohail, Ahmadi Keivan, Ahmed Anwar E., Ahmed Muktar Beshir, Ahmed Rushdia, Akalu Temesgen Yihunie, Alahdab Fares, Al-Aly Ziyad, Alam Noore, Alam Samiah, Alamene Genet Melak, Alanzi Turki M., Alcalde-Rabanal Jacqueline Elizabeth, Ali Beriwan Abdulqadir, Alijanzadeh Mehran, Alipour Vahid, Aljunid Syed Mohamed, Almasi Ali, Almasi-Hashiani Amir, Al-Mekhlafi Hesham M., Altirkawi Khalid A., Alvis-Guzman Nelson, Alvis-Zakzuk Nelson J., Amini Saeed, Amit Arianna Maever L., Andrei Catalina Liliana, Anjomshoa Mina, Anoushiravani Amir, Ansari Fereshteh, Antonio Carl Abelardo T., Antony Benny, Antriyandarti Ernoiz, Arabloo Jalal, Aref Hany Mohamed Amin, Aremu Olatunde, Armoon Bahram, Arora Amit, Aryal Krishna K., Arzani Afsaneh, Asadi-Aliabadi Mehran, Atalay Hagos Tasew, Athari Seyyed Shamsadin, Athari Seyyede Masoume, Atre Sachin R., Ausloos Marcel, Awoke Nefsu, Quintanilla Beatriz Paulina Ayala, Ayano Getinet, Ayanore Martin Amogre, Aynalem Yared Asmare, Azari Samad, Azzopardi Peter S., Babaee Ebrahim, Babalola Tesleem Kayode, Badawi Alaa, Bairwa Mohan, Bakkannavar Shankar M., Balakrishnan Senthilkumar, Bali Ayele Geleto, Banach Maciej, Banoub Joseph Adel Mattar, Barac Aleksandra, Barnighausen Till Winfried, Basaleem Huda, Basu Sanjay, Bay Vo Dinh, Bayati Mohsen, Baye Estifanos, Bedi Neeraj, Beheshti Mahya, Behzadifar Masoud, Behzadifar Meysam, Bekele Bayu Begashaw, Belayneh Yaschilal Muche, Bell Michelle L., Bennett Derrick A., Berbada Dessalegn Ajema, Bernstein Robert S., Bhat Anusha Ganapati, Bhattacharyya Krittika, Bhattarai Suraj, Bhaumik Soumyadeep, Bhutta Zulfiqar A., Bijani Ali, Bikbov Boris, Birihane Binyam Minuye, Biswas Raaj Kishore, Bohlouli Somayeh, Bojia Hunduma Amensisa, Boufous Soufiane, Brady Oliver J., Bragazzi Nicola Luigi, Briko Andrey Nikolaevich, Briko Nikolay Ivanovich, Britton Gabrielle B., Nagaraja Sharath Burugina, Busse Reinhard, Butt Zahid A., Camera Luis Alberto, Campos-Nonato Ismael R., Cano Jorge, Car Josip, Cardenas Rosario, Carvalho Felix, Castaneda-Orjuela Carlos A., Castro Franz, Chanie Wagaye Fentahun, Chatterjee Pranab, Chattu Vijay Kumar, Chichiabellu Tesfaye Yitna, Chin Ken Lee, Christopher Devasahayam J., Chu Dinh-Toi, Cormier Natalie Maria, Costa Vera Marisa, Culquichicon Carlos, Daba Matiwos Soboka, Damiani Giovanni, Dandona Lalit, Dandona Rakhi, Dang Anh Kim, Darwesh Aso Mohammad, Darwish Amira Hamed, Daryani Ahmad, Das Jai K., Das Gupta Rajat, Dash Aditya Prasad, Davey Gail, Davila-Cervantes Claudio Alberto, Davis Adrian C., Davitoiu Dragos Virgil, De la Hoz Fernando Pio, Demis Asmamaw Bizuneh, Demissie Dereje Bayissa, Demissie Getu Debalkie, Demoz Gebre Teklemariam, Demoz Gebre Teklemariam, Denova-Gutierrez Edgar, Deribe Kebede, Desalew Assefa, Deshpande Aniruddha, Dharmaratne Samath Dhamminda, Dhillon Preeti, Dhimal Meghnath, Dhungana Govinda Prasad, Diaz Daniel, Dipeolu Isaac Oluwafemi, Djalalinia Shirin, Doyle Kerrie E., Dubljanin Eleonora, Duko Bereket, Duraes Andre Rodrigues, Kalan Mohammad Ebrahimi, Edinur Hisham Atan, Effiong Andem, Eftekhari Aziz, El Nahas Nevine, El Sayed Iman, Zaki Maysaa El Sayed, El Tantawi Maha, Elema Teshome Bekele, Elhabashy Hala Rashad, El-Jaafary Shaimaa I., Elkout Hajer, Elsharkawy Aisha, Elyazar Iqbal R. F., Endalamaw Aklilu, Endalew Daniel Adane, Eskandarieh Sharareh, Esteghamati Alireza, Esteghamati Sadaf, Etemadi Arash, Ezekannagha Oluchi, Fareed Mohammad, Faridnia Roghiyeh, Farzadfar Farshad, Fazlzadeh Mehdi, Feigin Valery L., Fereshtehnejad Seyed-Mohammad, Fernandes Eduarda, Filip Irina, Fischer Florian, Foigt Nataliya A., Folayan Morenike Oluwatoyin, Foroutan Masoud, Franklin Richard Charles, Fukumoto Takeshi, Gad Mohamed M., Gayesa Reta Tsegaye, Gebre Teshome, Gebremedhin Ketema Bizuwork, Gebremeskel Gebreamlak Gebremedhn, Gesesew Hailay Abrha, Gezae Kebede Embaye, Ghadiri Keyghobad, Ghashghaee Ahmad, Ghimire Pramesh Raj, Gill Paramjit Singh, Gill Tiffany K., Ginindza Themba G., Gomes Nelson G. M., Gopalani Sameer Vali, Goulart Alessandra C., Goulart Barbara Niegia Garcia, Grada Ayman, Gubari Mohammed Ibrahim Mohialdeen, Gugnani Harish Chander, Guido Davide, Guimaraes Rafael Alves, Guo Yuming, Gupta Rajeev, Hafezi-Nejad Nima, Haile Dessalegn H., Hailu Gessessew Bugssa, Haj-Mirzaian Arvin, Haj-Mirzaian Arya, Hamadeh Randah R., Hamidi Samer, Handiso Demelash Woldeyohannes, Haririan Hamidreza, Hariyani Ninuk, Hasaballah Ahmed I., Hasan Md Mehedi, Hasanpoor Edris, Hasanzadeh Amir, Hassankhani Hadi, Hassen Hamid Yimam, Hegazy Mohamed I., Heibati Behzad, Heidari Behnam, Hendrie Delia, Henry Nathaniel J., Herteliu Claudiu, Heydarpour Fatemeh, de Hidru Hagos Degefa, Hird Thomas R., Hoang Chi Linh, Rad Enayatollah Homaie, Hoogar Praveen, Hoseini Mohammad, Hossain Naznin, Hosseini Mostafa, Hosseinzadeh Mehdi, Househ Mowafa, Hsairi Mohamed, Hu Guoqing, Hussen Mohammedaman Mama, Ibitoye Segun Emmanuel, Igumbor Ehimario U., Ilesanmi Olayinka Stephen, Ilic Milena D., Imani-Nasab Mohammad Hasan, Iqbal Usman, Irvani Seyed Sina Naghibi, Islam Sheikh Mohammed Shariful, Iwu Chinwe Juliana, Izadi Neda, Jaca Anelisa, Jahanmehr Nader, Jakovljevic Mihajlo, Jalali Amir, Jayatilleke Achala Upendra, Jha Ravi Prakash, Jha Vivekanand, Ji John S., Jonas Jost B., Jozwiak Jacek Jerzy, Kabir Ali, Kabir Zubair, Kahsay Amaha, Kalani Hamed, Kanchan Tanuj, Matin Behzad Karami, Karch Andre, Karim Mohd Anisul, Karki Hamidreza Karimi-Sari Surendra, Kasaeian Amir, Kasahun Gebremicheal Gebreslassie, Kasahun Yawukal Chane, Kasaye Habtamu Kebebe, Kassa Gebrehiwot G., Kassa Getachew Mullu, Kayode Gbenga A., Karyani Ali Kazemi, Kebede Mihiretu M., Keiyoro Peter Njenga, Kelbore Abraham Getachew, Kengne Andre Pascal, Ketema Daniel Bekele, Khader Yousef Saleh, Khafaie Morteza Abdullatif, Khalid Nauman, Khalilov Rovshan, Khan Ejaz Ahmad, Khan Junaid, Khan Md Nuruzzaman, Khan Muhammad Shahzeb, Khatab Khaled, Khater Amir M., Khater Mona M., Khayamzadeh Maryam, Khazaei Mohammad, Khazaei Salman, Khosravi Mohammad Hossein, Khubchandani Jagdish, Kiadaliri Ali, Kim Yun Jin, Kimokoti Ruth W., Kisa Adnan, Kisa Sezer, Kissoon Niranjan, Shivakumar K. M., Kochhar Sonali, Kolola Tufa, Komaki Hamidreza, Kosen Soewarta, Koul Parvaiz A., Koyanagi Ai, Kraemer Moritz U. G., Krishan Kewal, Kugbey Nuworza, Kumar G. Anil, Kumar Manasi, Kumar Pushpendra, Kusuma Vivek Kumar Dian, La Vecchia Carlo, Lacey Ben, Lad Sheetal D., Lal Dharmesh Kumar, Lam Felix, Lami Faris Hasan, Lamichhane Prabhat, Lansingh Van Charles, Lasrado Savita, Laxmaiah Avula, Lee Paul H., LeGrand Kate E., Leili Mostafa, Lenjebo Tsegaye Lolaso, Leshargie Cheru Tesema, Levine Aubrey J., Li Shanshan, Linn Shai, Liu Shiwei, Liu Simin, Lodha Rakesh, Longbottom Joshua, Lopez Jaifred Christian F., Abd El Razek Hassan Magdy, Abd El Razek Muhammed Magdy, Prasad D. R. Mahadeshwara, Mahasha Phetole Walter, Mahotra Narayan B., Majeed Azeem, Malekzadeh Reza, Malta Deborah Carvalho, Mamun Abdullah A., Manafi Navid, Manda Ana Laura, Manohar Narendar Dawani Dawanu, Mansournia Mohammad Ali, Mapoma Chabila Christopher, Maravilla Joemer C., Martinez Gabriel, Martini Santi, Martins-Melo Francisco Rogerlandio, Masaka Anthony, Massenburg Benjamin Ballard, Mathur Manu Raj, Mayala Benjamin K., Mazidi Mohsen, McAlinden Colm, Meharie Birhanu Geta, Mehndiratta Man Mohan, Mehta Kala M., Mekonnen Tefera Chane, Meles Gebrekiros Gebremichael, Memiah Peter T. N., Memish Ziad A., Mendoza Walter, Menezes Ritesh G., Mereta Seid Tiku, Meretoja Tuomo J., Mestrovic Tomislav, Miazgowski Bartosz, Mihretie Kebadnew Mulatu, Miller Ted R., Mini G. K., Mirrakhimov Erkin M., Moazen Babak, Mohajer Bahram, Mohamadi-Bolbanabad Amjad, Mohammad Dara K., Mohammad Karzan Abdulmuhsin, Mohammad Yousef, Mezerji Naser Mohammad Gholi, Mohammadibakhsh Roghayeh, Mohammadifard Noushin, Mohammed Jemal Abdu, Mohammed Shafiu, Mohebi Farnam, Mokdad Ali H., Molokhia Mariam, Monasta Lorenzo, Moodley Yoshan, Moore Catrin E., Moradi Ghobad, Moradi Masoud, Moradi-Joo Mohammad, Moradi-Lakeh Maziar, Moraga Paula, Morales Linda, Velasquez Ilais Moreno, Mosapour Abbas, Mouodi Simin, Mousavi Seyyed Meysam, Mozaffor Miliva, Muchie Kindie Fentahun, Mulaw Getahun Fentaw, Munro Sandra B., Muriithi Moses K., Murray Christoper J. L., Murthy G. V. S., Musa Kamarul Imran, Mustafa Ghulam, Muthupandian Saravanan, Nabhan Ashraf F., Naderi Mehdi, Nagarajan Ahamarshan Jayaraman, Naidoo Kovin S., Naik Gurudatta, Najafi Farid, Nangia Vinay, Nansseu Jobert Richie, Nascimento Bruno Ramos, Nazari Javad, Ndwandwe Duduzile Edith, Negoi Ionut, Netsere Henok Biresaw, Ngunjiri Josephine W., Nguyen Cuong Tat, Nguyen Huong Lan Thi, Nguyen Trang Huyen, Nigatu Dabere, Nigatu Solomon Gedlu, Ningrum Dina Nur Anggraini, Nnaji Chukwudi A., Nojomi Marzieh, Nong Vuong Minh, Norheim Ole F., Noubiap Jean Jacques, Motlagh Soraya Nouraei, Oancea Bogdan, Ogah Okechukwu Samuel, Ogbo Felix Akpojene, Oh In-Hwan, Olagunju Andrew T., Olagunju Tinuke O., Olusanya Bolajoko Olubukunola, Olusanya Jacob Olusegun, Onwujekwe Obinna E., Oren Eyal, Ortega-Altamirano Doris V., Osarenotor Osayomwanbo, Osei Frank B., Owolabi Mayowa O., Mahesh P. A., Padubidri Jagadish Rao, Pakhale Smita, Patel Sangram Kishor, Paternina-Caicedo Angel J., Pathak Ashish, Patton George C., Paudel Deepak, Paulos Kebreab, Pepito Veincent Christian Filipino, Pereira Alexandre, Perico Norberto, Pervaiz Aslam, Pescarini Julia Moreira, Piroozi Bakhtiar, Pirsaheb Meghdad, Postma Maarten J., Pourjafar Hadi, Pourmalek Farshad, Pourshams Akram, Poustchi Hossein, Prada Sergio I., Prasad Narayan, Preotescu Liliana, Quintana Hedley, Rabiee Navid, Radfar Amir, Rafiei Alireza, Rahim Fakher, Rahimi-Movaghar Afarin, Rahimi-Movaghar Vafa, Rahman Mohammad Hifz Ur, Rahman Muhammad Aziz, Rahman Shafiur, Rajati Fatemeh, Rana Saleem Muhammad, Ranabhat Chhabi Lal, Rasella Davide, Rawaf David Laith, Rawaf Salman, Rawal Lal, Rawasia Wasiq Faraz, Renjith Vishnu, Renzaho Andre M. N., Resnikoff Serge, Reta Melese Abate, Rezaei Negar, Rezai Mohammad Sadegh, Riahi Seyed Mohammad, Ribeiro Ana Isabel, Rickard Jennifer, Rios-Blancas Maria, Roever Leonardo, Ronfani Luca, Roro Elias Merdassa, Ross Jennifer M., Rubagotti Enrico, Rubino Salvatore, Saad Anas M., Sabde Yogesh Damodar, Sabour Siamak, Sadeghi Ehsan, Safari Yahya, Safari-Faramani Roya, Sagar Rajesh, Sahebkar Amirhossein, Sahraian Mohammad Ali, Sajadi S. Mohammad, Salahshoor Mohammad Reza, Salam Nasir, Salamati Payman, Salem Hosni, Salem Marwa Rashad, Salimi Yahya, Salimzadeh Hamideh, Samy Abdallah M., Sanabria Juan, Santric-Milicevic Milena M., Jose Bruno Piassi Sao, Saraswathy Sivan Yegnanarayana Iyer, Sarkar Kaushik, Sarker Abdur Razzaque, Sarrafzadegan Nizal, Sartorius Benn, Sathian Brijesh, Sathish Thirunavukkarasu, Sawhney Monika, Saxena Sonia, Schwebel David C., Senbeta Anbissa Muleta, Senthilkumaran Subramanian, Sepanlou Sadaf G., Servan-Mori Edson, Shabaninejad Hosein, Shafieesabet Azadeh, Shaikh Masood Ali, Shalash Ali S., Shallo Seifadin Ahmed, Shams-Beyranvand Mehran, Shamsi MohammadBagher, Shamsizadeh Morteza, Shannawaz Mohammed, Sharafi Kiomars, Sharifi Hamid, Shehata Hatem Samir, Sheikh Aziz, Shetty B. Suresh Kumar, Shibuya Kenji, Shiferaw Wondimeneh Shibabaw, Shifti Desalegn Markos, Shigematsu Mika, Il Shin Jae, Shiri Rahman, Shirkoohi Reza, Siabani Soraya, Siddiqi Tariq Jamal, Silva Diego Augusto Santos, Singh Ambrish, Singh Jasvinder A., Singh Narinder Pal, Singh Virendra, Sisay Malede Mequanent, Skiadaresi Eirini, Sobhiyeh Mohammad Reza, Sokhan Anton, Soltani Shahin, Somayaji Ranjani, Soofi Moslem, Sorrie Muluken Bekele, Soyiri Ireneous N., Sreeramareddy Chandrashekhar T., Sudaryanto Agus, Sufiyan Mu'awiyyah Babale, Suleria Hafiz Ansar Rasul, Sultana Marufa, Sunguya Bruno Fokas, Sykes Bryan L., Tabares-Seisdedos Rafael, Tabuchi Takahiro, Tadesse Degena Bahrey, Tarigan Ingan Ukur, Tasew Aberash Abay, Tefera Yonatal Mesfin, Tekle Merhawi Gebremedhin, Temsah Mohamad-Hani, Tesfay Berhe Etsay, Tesfay Fisaha Haile, Tessema Belay, Tessema Zemenu Tadesse, Thankappan Kavumpurathu Raman, Thomas Nihal, Toma Alemayehu, Topor-Madry Roman, Tovani-Palone Marcos Roberto, Traini Eugenio, Tran Bach Xuan, Tran Khanh Bao, Ullah Irfan, Unnikrishnan Bhaskaran, Usman Muhammad Shariq, Uzochukwu Benjamin S. Chudi, Valdez Pascual R., Varughese Santosh, Violante Francesco S., Vollmer Sebastian, Hawariat Feleke Gebremeskel W., Waheed Yasir, Wallin Mitchell Taylor, Wang Yafeng, Wang Yuan-Pang, Weaver Marcia, Weji Bedilu Girma, Weldesamuel Girmay Teklay, Welgan Catherine A., Werdecker Andrea, Westerman Ronny, Wiangkham Taweewat, Wiysonge Charles Shey, Wolde Haileab Fekadu, Wondafrash Dawit Zewdu, Wonde Tewodros Eshete, Worku Getasew Taddesse, Wu Ai-Min, Xu Gelin, Yadollahpour Ali, Jabbari Seyed Hossein Yahyazadeh, Yamada Tomohide, Yatsuya Hiroshi, Yeshaneh Alex, Yilgwan Christopher Sabo, Yilma Mekdes Tigistu, Yip Paul, Yisma Engida, Yonemoto Naohiro, Yoon Seok-Jun, Younis Mustafa Z., Yousefifard Mahmoud, Yousof Hebat-Allah Salah A., Yu Chuanhua, Yusefzadeh Hasan, Zadey Siddhesh, Zaidi Zoubida, Bin Zaman Sojib, Zamani Mohammad, Zandian Hamed, Zepro Nejimu Biza, Zerfu Taddese Alemu, Zhang Yunquan, Zhao Xiu-Ju George, Ziapour Arash, Zodpey Sanjay, Zuniga Yves Miel H., Hay Simon I., Reiner Robert C. Jr.

    LANCET GLOBAL HEALTH   8 巻 ( 8 ) 頁: 1038 - 1060   2020年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Web of Science

  77. Risk Factors of Infectious Complications After Endobronchial Ultrasound-Guided Transbronchial Biopsy. 査読有り 国際誌

    Souma T, Minezawa T, Yatsuya H, Okamura T, Yamatsuta K, Morikawa S, Horiguchi T, Maeda S, Goto Y, Hayashi M, Isogai S, Yamamoto N, Kondo M, Imaizumi K

    Chest   158 巻 ( 2 ) 頁: 797 - 807   2020年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.chest.2020.02.025

    PubMed

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  78. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17

    Wiens K.E., Lindstedt P.A., Blacker B.F., Johnson K.B., Baumann M.M., Schaeffer L.E., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahpour I., Abegaz K.H., Abejie A.N., Abreu L.G., Abrigo M.R.M., Abualhasan A., Accrombessi M.M.K., Acharya D., Adabi M., Adamu A.A., Adebayo O.M., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhena B.M., Afarideh M., Ahmad S., Ahmadi K., Ahmed A.E., Ahmed M.B., Ahmed R., Akalu T.Y., Alahdab F., Al-Aly Z., Alam N., Alam S., Alamene G.M., Alanzi T.M., Alcalde-Rabanal J.E., Ali B.A., Alijanzadeh M., Alipour V., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Alvis-Guzman N., Alvis-Zakzuk N.J., Amini S., Amit A.M.L., Andrei C.L., Anjomshoa M., Anoushiravani A., Ansari F., Antonio C.A.T., Antony B., Antriyandarti E., Arabloo J., Aref H.M.A., Aremu O., Armoon B., Arora A., Aryal K.K., Arzani A., Asadi-Aliabadi M., Atalay H.T., Athari S.S., Athari S.M., Atre S.R., Ausloos M., Awoke N., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azzopardi P.S., Babaee E., Babalola T.K., Badawi A., Bairwa M., Bakkannavar S.M., Balakrishnan S., Bali A.G., Banach M., Banoub J.A.M., Barac A., Bärnighausen T.W., Basaleem H., Basu S., Bay V.D., Bayati M., Baye E., Bedi N., Beheshti M., Behzadifar M., Behzadifar M., Bekele B.B., Belayneh Y.M., Bell M.L.

    The Lancet Global Health   8 巻 ( 8 ) 頁: e1038 - e1060   2020年8月

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    記述言語:日本語   出版者・発行元:The Lancet Global Health  

    Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs. Methods: We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000–17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2·5th and 97·5th percentiles of those 250 draws. Findings: While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62·6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000–7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT coverage from 2000 to 2017. Although ORS was uniformly distributed subnationally in some countries, within-country geographical inequalities persisted in others; 11 countries had at least a 50% difference in one of their units compared with the country mean. Increases in ORS use over time were correlated with declines in RHF use and in diarrhoeal mortality in many locations, and an estimated 52 230 diarrhoeal deaths (36 910–68 860) were averted by scaling up of ORS coverage between 2000 and 2017. Finally, we identified key subnational areas in Colombia, Nigeria, and Sudan as examples of where diarrhoeal mortality remains higher than average, while ORS coverage remains lower than average. Interpretation: To our knowledge, this study is the first to produce and map subnational estimates of ORS, RHF, and ORT coverage and attributable child diarrhoeal deaths across LMICs from 2000 to 2017, allowing for tracking progress over time. Our novel results, combined with detailed subnational estimates of diarrhoeal morbidity and mortality, can support subnational needs assessments aimed at furthering policy makers' understanding of within-country disparities. Over 50 years after the discovery that led to this simple, cheap, and life-saving therapy, large gains in reducing mortality could still be made by reducing geographical inequalities in ORS coverage. Funding: Bill & Melinda Gates Foundation.

    DOI: 10.1016/S2214-109X(20)30230-8

    Scopus

  79. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17

    Kirsten E. Wiens, Paulina A. Lindstedt, Brigette F. Blacker, Kimberly B. Johnson, Mathew M. Baumann, Lauren E. Schaeffer, Hedayat Abbastabar, Foad Abd-Allah, Ahmed Abdelalim, Ibrahim Abdollahpour, Kedir Hussein Abegaz, Ayenew Negesse Abejie, Lucas Guimaraes Abreu, Michael R. M. Abrigo, Ahmed Abualhasan, Manfred Mario Kokou Accrombessi, Dilaram Acharya, Maryam Adabi, Abdu A. Adamu, Oladimeji M. Adebayo, Rufus Adesoji Adedoyin, Victor Adekanmbi, Olatunji O. Adetokunboh, Beyene Meressa Adhena, Mohsen Afarideh, Sohail Ahmad, Keivan Ahmadi, Anwar E. Ahmed, Muktar Beshir Ahmed, Rushdia Ahmed, Temesgen Yihunie Akalu, Fares Alahdab, Ziyad Al-Aly, Noore Alam, Samiah Alam, Genet Melak Alamene, Turki M. Alanzi, Jacqueline Elizabeth Alcalde-Rabanal, Beriwan Abdulqadir Ali, Mehran Alijanzadeh, Vahid Alipour, Syed Mohamed Aljunid, Ali Almasi, Amir Almasi-Hashiani, Hesham M. Al-Mekhlafi, Khalid A. Altirkawi, Nelson Alvis-Guzman, Nelson J. Alvis-Zakzuk, Saeed Amini, Arianna Maever L. Amit, Catalina Liliana Andrei, Mina Anjomshoa, Amir Anoushiravani, Fereshteh Ansari, Carl Abelardo T. Antonio, Benny Antony, Ernoiz Antriyandarti, Jalal Arabloo, Hany Mohamed Amin Aref, Olatunde Aremu, Bahram Armoon, Amit Arora, Krishna K. Aryal, Afsaneh Arzani, Mehran Asadi-Aliabadi, Hagos Tasew Atalay, Seyyed Shamsadin Athari, Seyyede Masoume Athari, Sachin R. Atre, Marcel Ausloos, Nefsu Awoke, Beatriz Paulina Ayala Quintanilla, Getinet Ayano, Martin Amogre Ayanore, Yared Asmare Aynalem, Samad Azari, Peter S. Azzopardi, Ebrahim Babaee, Tesleem Kayode Babalola, Alaa Badawi, Mohan Bairwa, Shankar M. Bakkannavar, Senthilkumar Balakrishnan, Ayele Geleto Bali, Maciej Banach, Joseph Adel Mattar Banoub, Aleksandra Barac, Till Winfried Barnighausen, Huda Basaleem, Sanjay Basu, Vo Dinh Bay, Mohsen Bayati, Estifanos Baye, Neeraj Bedi, Mahya Beheshti, Masoud Behzadifar, Meysam Behzadifar, Bayu Begashaw Bekele, Yaschilal Muche Belayneh, Michelle L. Bell, Derrick A. Bennett, Dessalegn Ajema Berbada, Robert S. Bernstein, Anusha Ganapati Bhat, Krittika Bhattacharyya, Suraj Bhattarai, Soumyadeep Bhaumik, Zulfiqar A. Bhutta, Ali Bijani, Boris Bikbov, Binyam Minuye Birihane, Raaj Kishore Biswas, Somayeh Bohlouli, Hunduma Amensisa Bojia, Soufiane Boufous, Oliver J. Brady, Nicola Luigi Bragazzi, Andrey Nikolaevich Briko, Nikolay Ivanovich Briko, Gabrielle B. Britton, Sharath Burugina Nagaraja, Reinhard Busse, Zahid A. Butt, Luis Alberto Camera, Ismael R. Campos-Nonato, Jorge Cano, Josip Car, Rosario Cardenas, Felix Carvalho, Carlos A. Castaneda-Orjuela, Franz Castro, Wagaye Fentahun Chanie, Pranab Chatterjee, Vijay Kumar Chattu, Tesfaye Yitna Chichiabellu, Ken Lee Chin, Devasahayam J. Christopher, Dinh-Toi Chu, Natalie Maria Cormier, Vera Marisa Costa, Carlos Culquichicon, Matiwos Soboka Daba, Giovanni Damiani, Lalit Dandona, Rakhi Dandona, Anh Kim Dang, Aso Mohammad Darwesh, Amira Hamed Darwish, Ahmad Daryani, Jai K. Das, Rajat Das Gupta, Aditya Prasad Dash, Gail Davey, Claudio Alberto Davila-Cervantes, Adrian C. Davis, Dragos Virgil Davitoiu, Fernando Pio De la Hoz, Asmamaw Bizuneh Demis, Dereje Bayissa Demissie, Getu Debalkie Demissie, Gebre Teklemariam Demoz, Gebre Teklemariam Demoz, Edgar Denova-Gutierrez, Kebede Deribe, Assefa Desalew, Aniruddha Deshpande, Samath Dhamminda Dharmaratne, Preeti Dhillon, Meghnath Dhimal, Govinda Prasad Dhungana, Daniel Diaz, Isaac Oluwafemi Dipeolu, Shirin Djalalinia, Kerrie E. Doyle, Eleonora Dubljanin, Bereket Duko, Andre Rodrigues Duraes, Mohammad Ebrahimi Kalan, Hisham Atan Edinur, Andem Effiong, Aziz Eftekhari, Nevine El Nahas, Iman El Sayed, Maysaa El Sayed Zaki, Maha El Tantawi, Teshome Bekele Elema, Hala Rashad Elhabashy, Shaimaa I. El-Jaafary, Hajer Elkout, Aisha Elsharkawy, Iqbal R. F. Elyazar, Aklilu Endalamaw, Daniel Adane Endalew, Sharareh Eskandarieh, Alireza Esteghamati, Sadaf Esteghamati, Arash Etemadi, Oluchi Ezekannagha, Mohammad Fareed, Roghiyeh Faridnia, Farshad Farzadfar, Mehdi Fazlzadeh, Valery L. Feigin, Seyed-Mohammad Fereshtehnejad, Eduarda Fernandes, Irina Filip, Florian Fischer, Nataliya A. Foigt, Morenike Oluwatoyin Folayan, Masoud Foroutan, Richard Charles Franklin, Takeshi Fukumoto, Mohamed M. Gad, Reta Tsegaye Gayesa, Teshome Gebre, Ketema Bizuwork Gebremedhin, Gebreamlak Gebremedhn Gebremeskel, Hailay Abrha Gesesew, Kebede Embaye Gezae, Keyghobad Ghadiri, Ahmad Ghashghaee, Pramesh Raj Ghimire, Paramjit Singh Gill, Tiffany K. Gill, Themba G. Ginindza, Nelson G. M. Gomes, Sameer Vali Gopalani, Alessandra C. Goulart, Barbara Niegia Garcia Goulart, Ayman Grada, Mohammed Ibrahim Mohialdeen Gubari, Harish Chander Gugnani, Davide Guido, Rafael Alves Guimaraes, Yuming Guo, Rajeev Gupta, Nima Hafezi-Nejad, Dessalegn H. Haile, Gessessew Bugssa Hailu, Arvin Haj-Mirzaian, Arya Haj-Mirzaian, Randah R. Hamadeh, Samer Hamidi, Demelash Woldeyohannes Handiso, Hamidreza Haririan, Ninuk Hariyani, Ahmed I. Hasaballah, Md Mehedi Hasan, Edris Hasanpoor, Amir Hasanzadeh, Hadi Hassankhani, Hamid Yimam Hassen, Mohamed I. Hegazy, Behzad Heibati, Behnam Heidari, Delia Hendrie, Nathaniel J. Henry, Claudiu Herteliu, Fatemeh Heydarpour, Hagos Degefa de Hidru, Thomas R. Hird, Chi Linh Hoang, Enayatollah Homaie Rad, Praveen Hoogar, Mohammad Hoseini, Naznin Hossain, Mostafa Hosseini, Mehdi Hosseinzadeh, Mowafa Househ, Mohamed Hsairi, Guoqing Hu, Mohammedaman Mama Hussen, Segun Emmanuel Ibitoye, Ehimario U. Igumbor, Olayinka Stephen Ilesanmi, Milena D. Ilic, Mohammad Hasan Imani-Nasab, Usman Iqbal, Seyed Sina Naghibi Irvani, Sheikh Mohammed Shariful Islam, Chinwe Juliana Iwu, Neda Izadi, Anelisa Jaca, Nader Jahanmehr, Mihajlo Jakovljevic, Amir Jalali, Achala Upendra Jayatilleke, Ravi Prakash Jha, Vivekanand Jha, John S. Ji, Jost B. Jonas, Jacek Jerzy Jozwiak, Ali Kabir, Zubair Kabir, Amaha Kahsay, Hamed Kalani, Tanuj Kanchan, Behzad Karami Matin, Andre Karch, Mohd Anisul Karim, Hamidreza Karimi-Sari Surendra Karki, Amir Kasaeian, Gebremicheal Gebreslassie Kasahun, Yawukal Chane Kasahun, Habtamu Kebebe Kasaye, Gebrehiwot G. Kassa, Getachew Mullu Kassa, Gbenga A. Kayode, Ali Kazemi Karyani, Mihiretu M. Kebede, Peter Njenga Keiyoro, Abraham Getachew Kelbore, Andre Pascal Kengne, Daniel Bekele Ketema, Yousef Saleh Khader, Morteza Abdullatif Khafaie, Nauman Khalid, Rovshan Khalilov, Ejaz Ahmad Khan, Junaid Khan, Md Nuruzzaman Khan, Muhammad Shahzeb Khan, Khaled Khatab, Amir M. Khater, Mona M. Khater, Maryam Khayamzadeh, Mohammad Khazaei, Salman Khazaei, Mohammad Hossein Khosravi, Jagdish Khubchandani, Ali Kiadaliri, Yun Jin Kim, Ruth W. Kimokoti, Adnan Kisa, Sezer Kisa, Niranjan Kissoon, K. M. Shivakumar, Sonali Kochhar, Tufa Kolola, Hamidreza Komaki, Soewarta Kosen, Parvaiz A. Koul, Ai Koyanagi, Moritz U. G. Kraemer, Kewal Krishan, Nuworza Kugbey, G. Anil Kumar, Manasi Kumar, Pushpendra Kumar, Vivek Kumar Dian Kusuma, Carlo La Vecchia, Ben Lacey, Sheetal D. Lad, Dharmesh Kumar Lal, Felix Lam, Faris Hasan Lami, Prabhat Lamichhane, Van Charles Lansingh, Savita Lasrado, Avula Laxmaiah, Paul H. Lee, Kate E. LeGrand, Mostafa Leili, Tsegaye Lolaso Lenjebo, Cheru Tesema Leshargie, Aubrey J. Levine, Shanshan Li, Shai Linn, Shiwei Liu, Simin Liu, Rakesh Lodha, Joshua Longbottom, Jaifred Christian F. Lopez, Hassan Magdy Abd El Razek, Muhammed Magdy Abd El Razek, D. R. Mahadeshwara Prasad, Phetole Walter Mahasha, Narayan B. Mahotra, Azeem Majeed, Reza Malekzadeh, Deborah Carvalho Malta, Abdullah A. Mamun, Navid Manafi, Ana Laura Manda, Narendar Dawani Dawanu Manohar, Mohammad Ali Mansournia, Chabila Christopher Mapoma, Joemer C. Maravilla, Gabriel Martinez, Santi Martini, Francisco Rogerlandio Martins-Melo, Anthony Masaka, Benjamin Ballard Massenburg, Manu Raj Mathur, Benjamin K. Mayala, Mohsen Mazidi, Colm McAlinden, Birhanu Geta Meharie, Man Mohan Mehndiratta, Kala M. Mehta, Tefera Chane Mekonnen, Gebrekiros Gebremichael Meles, Peter T. N. Memiah, Ziad A. Memish, Walter Mendoza, Ritesh G. Menezes, Seid Tiku Mereta, Tuomo J. Meretoja, Tomislav Mestrovic, Bartosz Miazgowski, Kebadnew Mulatu Mihretie, Ted R. Miller, G. K. Mini, Erkin M. Mirrakhimov, Babak Moazen, Bahram Mohajer, Amjad Mohamadi-Bolbanabad, Dara K. Mohammad, Karzan Abdulmuhsin Mohammad, Yousef Mohammad, Naser Mohammad Gholi Mezerji, Roghayeh Mohammadibakhsh, Noushin Mohammadifard, Jemal Abdu Mohammed, Shafiu Mohammed, Farnam Mohebi, Ali H. Mokdad, Mariam Molokhia, Lorenzo Monasta, Yoshan Moodley, Catrin E. Moore, Ghobad Moradi, Masoud Moradi, Mohammad Moradi-Joo, Maziar Moradi-Lakeh, Paula Moraga, Linda Morales, Ilais Moreno Velasquez, Abbas Mosapour, Simin Mouodi, Seyyed Meysam Mousavi, Miliva Mozaffor, Kindie Fentahun Muchie, Getahun Fentaw Mulaw, Sandra B. Munro, Moses K. Muriithi, Christoper J. L. Murray, G. V. S. Murthy, Kamarul Imran Musa, Ghulam Mustafa, Saravanan Muthupandian, Ashraf F. Nabhan, Mehdi Naderi, Ahamarshan Jayaraman Nagarajan, Kovin S. Naidoo, Gurudatta Naik, Farid Najafi, Vinay Nangia, Jobert Richie Nansseu, Bruno Ramos Nascimento, Javad Nazari, Duduzile Edith Ndwandwe, Ionut Negoi, Henok Biresaw Netsere, Josephine W. Ngunjiri, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Trang Huyen Nguyen, Dabere Nigatu, Solomon Gedlu Nigatu, Dina Nur Anggraini Ningrum, Chukwudi A. Nnaji, Marzieh Nojomi, Vuong Minh Nong, Ole F. Norheim, Jean Jacques Noubiap, Soraya Nouraei Motlagh, Bogdan Oancea, Okechukwu Samuel Ogah, Felix Akpojene Ogbo, In-Hwan Oh, Andrew T. Olagunju, Tinuke O. Olagunju, Bolajoko Olubukunola Olusanya, Jacob Olusegun Olusanya, Obinna E. Onwujekwe, Eyal Oren, Doris V. Ortega-Altamirano, Osayomwanbo Osarenotor, Frank B. Osei, Mayowa O. Owolabi, P. A. Mahesh, Jagadish Rao Padubidri, Smita Pakhale, Sangram Kishor Patel, Angel J. Paternina-Caicedo, Ashish Pathak, George C. Patton, Deepak Paudel, Kebreab Paulos, Veincent Christian Filipino Pepito, Alexandre Pereira, Norberto Perico, Aslam Pervaiz, Julia Moreira Pescarini, Bakhtiar Piroozi, Meghdad Pirsaheb, Maarten J. Postma, Hadi Pourjafar, Farshad Pourmalek, Akram Pourshams, Hossein Poustchi, Sergio I. Prada, Narayan Prasad, Liliana Preotescu, Hedley Quintana, Navid Rabiee, Amir Radfar, Alireza Rafiei, Fakher Rahim, Afarin Rahimi-Movaghar, Vafa Rahimi-Movaghar, Mohammad Hifz Ur Rahman, Muhammad Aziz Rahman, Shafiur Rahman, Fatemeh Rajati, Saleem Muhammad Rana, Chhabi Lal Ranabhat, Davide Rasella, David Laith Rawaf, Salman Rawaf, Lal Rawal, Wasiq Faraz Rawasia, Vishnu Renjith, Andre M. N. Renzaho, Serge Resnikoff, Melese Abate Reta, Negar Rezaei, Mohammad Sadegh Rezai, Seyed Mohammad Riahi, Ana Isabel Ribeiro, Jennifer Rickard, Maria Rios-Blancas, Leonardo Roever, Luca Ronfani, Elias Merdassa Roro, Jennifer M. Ross, Enrico Rubagotti, Salvatore Rubino, Anas M. Saad, Yogesh Damodar Sabde, Siamak Sabour, Ehsan Sadeghi, Yahya Safari, Roya Safari-Faramani, Rajesh Sagar, Amirhossein Sahebkar, Mohammad Ali Sahraian, S. Mohammad Sajadi, Mohammad Reza Salahshoor, Nasir Salam, Payman Salamati, Hosni Salem, Marwa Rashad Salem, Yahya Salimi, Hamideh Salimzadeh, Abdallah M. Samy, Juan Sanabria, Milena M. Santric-Milicevic, Bruno Piassi Sao Jose, Sivan Yegnanarayana Iyer Saraswathy, Kaushik Sarkar, Abdur Razzaque Sarker, Nizal Sarrafzadegan, Benn Sartorius, Brijesh Sathian, Thirunavukkarasu Sathish, Monika Sawhney, Sonia Saxena, David C. Schwebel, Anbissa Muleta Senbeta, Subramanian Senthilkumaran, Sadaf G. Sepanlou, Edson Servan-Mori, Hosein Shabaninejad, Azadeh Shafieesabet, Masood Ali Shaikh, Ali S. Shalash, Seifadin Ahmed Shallo, Mehran Shams-Beyranvand, MohammadBagher Shamsi, Morteza Shamsizadeh, Mohammed Shannawaz, Kiomars Sharafi, Hamid Sharifi, Hatem Samir Shehata, Aziz Sheikh, B. Suresh Kumar Shetty, Kenji Shibuya, Wondimeneh Shibabaw Shiferaw, Desalegn Markos Shifti, Mika Shigematsu, Jae Il Shin, Rahman Shiri, Reza Shirkoohi, Soraya Siabani, Tariq Jamal Siddiqi, Diego Augusto Santos Silva, Ambrish Singh, Jasvinder A. Singh, Narinder Pal Singh, Virendra Singh, Malede Mequanent Sisay, Eirini Skiadaresi, Mohammad Reza Sobhiyeh, Anton Sokhan, Shahin Soltani, Ranjani Somayaji, Moslem Soofi, Muluken Bekele Sorrie, Ireneous N. Soyiri, Chandrashekhar T. Sreeramareddy, Agus Sudaryanto, Mu'awiyyah Babale Sufiyan, Hafiz Ansar Rasul Suleria, Marufa Sultana, Bruno Fokas Sunguya, Bryan L. Sykes, Rafael Tabares-Seisdedos, Takahiro Tabuchi, Degena Bahrey Tadesse, Ingan Ukur Tarigan, Aberash Abay Tasew, Yonatal Mesfin Tefera, Merhawi Gebremedhin Tekle, Mohamad-Hani Temsah, Berhe Etsay Tesfay, Fisaha Haile Tesfay, Belay Tessema, Zemenu Tadesse Tessema, Kavumpurathu Raman Thankappan, Nihal Thomas, Alemayehu Toma, Roman Topor-Madry, Marcos Roberto Tovani-Palone, Eugenio Traini, Bach Xuan Tran, Khanh Bao Tran, Irfan Ullah, Bhaskaran Unnikrishnan, Muhammad Shariq Usman, Benjamin S. Chudi Uzochukwu, Pascual R. Valdez, Santosh Varughese, Francesco S. Violante, Sebastian Vollmer, Feleke Gebremeskel W. Hawariat, Yasir Waheed, Mitchell Taylor Wallin, Yafeng Wang, Yuan-Pang Wang, Marcia Weaver, Bedilu Girma Weji, Girmay Teklay Weldesamuel, Catherine A. Welgan, Andrea Werdecker, Ronny Westerman, Taweewat Wiangkham, Charles Shey Wiysonge, Haileab Fekadu Wolde, Dawit Zewdu Wondafrash, Tewodros Eshete Wonde, Getasew Taddesse Worku, Ai-Min Wu, Gelin Xu, Ali Yadollahpour, Seyed Hossein Yahyazadeh Jabbari, Tomohide Yamada, Hiroshi Yatsuya, Alex Yeshaneh, Christopher Sabo Yilgwan, Mekdes Tigistu Yilma, Paul Yip, Engida Yisma, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z. Younis, Mahmoud Yousefifard, Hebat-Allah Salah A. Yousof, Chuanhua Yu, Hasan Yusefzadeh, Siddhesh Zadey, Zoubida Zaidi, Sojib Bin Zaman, Mohammad Zamani, Hamed Zandian, Nejimu Biza Zepro, Taddese Alemu Zerfu, Yunquan Zhang, Xiu-Ju George Zhao, Arash Ziapour, Sanjay Zodpey, Yves Miel H. Zuniga, Simon I. Hay, Robert C. Reiner

    LANCET GLOBAL HEALTH   8 巻 ( 8 ) 頁: 1038 - 1060   2020年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCI LTD  

    Background Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs.Methods We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000-17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2 center dot 5th and 97 center dot 5th percentiles of those 250 draws.Findings While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62 center dot 6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000-7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT coverage from 2000 to 2017. Although ORS was uniformly distributed subnationally in some countries, within-country geographical inequalities persisted in others; 11 countries had at least a 50% difference in one of their units compared with the country mean. Increases in ORS use over time were correlated with declines in RHF use and in diarrhoeal mortality in many locations, and an estimated 52 230 diarrhoeal deaths (36 910-68 860) were averted by scaling up of ORS coverage between 2000 and 2017. Finally, we identified key subnational areas in Colombia, Nigeria, and Sudan as examples of where diarrhoeal mortality remains higher than average, while ORS coverage remains lower than average.Interpretation To our knowledge, this study is the first to produce and map subnational estimates of ORS, RHF, and ORT coverage and attributable child diarrhoeal deaths across LMICs from 2000 to 2017, allowing for tracking progress over time. Our novel results, combined with detailed subnational estimates of diarrhoeal morbidity and mortality, can support subnational needs assessments aimed at furthering policy makers' understanding of within-country disparities. Over 50 years after the discovery that led to this simple, cheap, and life-saving therapy, large gains in reducing mortality could still be made by reducing geographical inequalities in ORS coverage. Copyright (c) 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

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  80. 安全衛生担当労働者における加熱式タバコの利用状況 査読有り

    厚生の指標   67 巻 ( 6 ) 頁: 23 - 28   2020年6月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    目的 職域では受動喫煙対策とともに喫煙労働者への禁煙指導が課題となっている。日本の職域における加熱式タバコの使用実態を報告した論文は少ない。本研究の目的は,職域における加熱式タバコの使用実態を把握し,喫煙対策の実施につながる知見を得ることである。方法 某労働災害防止団体の地方センターにおいて2019年4月〜6月末の3ヵ月間に開催した安全衛生教育受講者(819人)を対象にした自記式質問紙調査を実施した。喫煙率,加熱式タバコ利用状況,年齢,性別,役職,企業規模,喫煙習慣との関連を調べた。回答者741人のうち,男性回答者で分析に必要な項目に欠損がなかった653人を解析した。結果 喫煙率は37.8%(247人)であった。現喫煙者割合は40〜49歳で高く(40.1%),過去喫煙者割合は50歳以上で高く(37.8%),非喫煙者割合は40歳未満で高かった(49.1%)(p<0.001)。役職,企業規模と現喫煙,過去喫煙,非喫煙の割合に有意な関連は認めなかった。現喫煙者247人の内,加熱式タバコのみを利用する者が67人(現喫煙者の27.1%),加熱式タバコと通常のタバコとの併用者が55人(現喫煙者の22.3%)であった。加熱式タバコの利用状況(加熱式のみ,併用,通常のタバコのみ)と年齢,役職,企業規模との間に統計学的に有意な関連は認めなかった。加熱式タバコの利用理由は「においが少ない」(67.2%),「煙が少ない」(47.5%),「火の心配が少ない」(43.4%),「自分の健康被害が少ないと思う」(35.2%),「周囲の健康被害が少ないと思う」(34.4%)であった。結論 男性労働者の喫煙率には年齢による差はあったが,企業規模や役職による差はなかった。男性労働者の加熱式タバコの利用は20%程度で,全喫煙者の約半分であった。本研究では,健康被害よりもにおいや火に関連した危険を理由として加熱式タバコを利用する者が多かった。事業場においては,通常のタバコへの喫煙対策と併せて加熱式タバコへの対策も行うことが望まれる

  81. Habitual tub bathing and risks of incident coronary heart disease and stroke. 査読有り 国際誌

    Ukai T, Iso H, Yamagishi K, Saito I, Kokubo Y, Yatsuya H, Muraki I, Eshak ES, Sawada N, Tsugane S

    Heart (British Cardiac Society)   106 巻 ( 10 ) 頁: 732 - 737   2020年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1136/heartjnl-2019-315752

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  82. ウルソデオキシコール酸添加による高脂肪食誘導性肝炎・線維化の軽減作用

    内藤 久雄, 北森 一哉, 橋本 沙幸, 浅野 友美, 八谷 寛, 那須 民江

    産業衛生学雑誌   62 巻 ( 臨増 ) 頁: 610 - 610   2020年5月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  83. Non-High-Density Lipoprotein Cholesterol and Risk of Stroke Subtypes and Coronary Heart Disease: The Japan Public Health Center-Based Prospective (JPHC) Study. 査読有り

    Saito I, Yamagishi K, Kokubo Y, Yatsuya H, Iso H, Sawada N, Inoue M, Tsugane S

    Journal of atherosclerosis and thrombosis   27 巻 ( 4 ) 頁: 363 - 374   2020年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.5551/jat.50385

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  84. 降圧薬ヒドララジンは高脂肪食摂取した高血圧ラットの肝線維化を抑制する

    内藤 久雄, 袁 媛, 北森 一哉, 橋本 沙幸, 浅野 友美, 八谷 寛, 那須 民江

    日本衛生学雑誌   75 巻 ( Suppl. ) 頁: S161 - S161   2020年3月

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    記述言語:日本語   出版者・発行元:(一社)日本衛生学会  

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  85. トリクロロエチレン曝露によるCYP2E1抗体の上昇とその影響因子

    那須 民江, 王 海蘭, 袁 媛, 内藤 久雄, 伊藤 由起, 柳場 由絵, 八谷 寛, 上島 通浩

    産業衛生学雑誌   62 巻 ( 2 ) 頁: 105 - 105   2020年3月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  86. 労働者の生活習慣指導のありかた 特定健康診査による保健指導レベルと2型糖尿病発症の関連およびその人口寄与危険割合 愛知職域コホート研究

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 内藤 久雄, 太田 充彦, 玉腰 浩司, 青山 温子

    産業衛生学雑誌   62 巻 ( 2 ) 頁: 94 - 94   2020年3月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  87. 降圧薬ヒドララジンは高脂肪食摂取した高血圧ラットの肝線維化を抑制する

    内藤 久雄, 袁 媛, 北森 一哉, 橋本 沙幸, 浅野 友美, 八谷 寛, 那須 民江

    日本衛生学雑誌   75 巻 ( Suppl. ) 頁: S161 - S161   2020年3月

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    記述言語:日本語   出版者・発行元:(一社)日本衛生学会  

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  88. Human herpesvirus-6B infection in pediatric allogenic hematopoietic stem cell transplant patients: Risk factors and encephalitis. 査読有り 国際誌

    Miura H, Kawamura Y, Hattori F, Tanaka M, Kudo K, Ihira M, Yatsuya H, Takahashi Y, Kojima S, Sakaguchi H, Yoshida N, Hama A, Yoshikawa T

    Transplant infectious disease : an official journal of the Transplantation Society   22 巻 ( 1 ) 頁: e13203   2020年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Transplant Infectious Disease  

    Background: Human herpesvirus-6B (HHV-6B) infection after allogenic hematopoietic stem cell transplantation (allo-HSCT) is known to be associated with post-transplant limbic encephalitis in adults. Meanwhile, the association between HHV-6B infection and central nervous system complications remains unclear in pediatric allo-HSCT patients. Methods: In this study, HHV-6B infection was monitored for more than 50 days after HSCT using virus isolation and real-time PCR. Clinical information such as patient background and encephalitis status was collected retrospectively from medical records. Risk factors for HHV-6B infection were determined by the Cox proportional hazards model, and the clinical features of HHV-6B encephalitis in pediatric allo-HSCT patients were elucidated. Results: Human herpesvirus-6B infection was observed in 74 (33.8%) of 219 patients at 3-47 days (median 18, interquartile range 13-20). Risk factors identified in multivariable analysis were hematological malignancy (hazards ratio [HR], 5.0; 95% confidence interval [CI], 2.3/12.5; P <.0001), solid tumor (HR, 4.8; CI, 1.5/16.3; P =.0104), unrelated donor (HR, 2.1; CI, 1.0/4.6; P =.0378), and sex-mismatched donor (HR 1.8; CI, 1.1/3.0; P =.0257). HHV-6B encephalitis occurred in only one of the 219 patients (0.46%); this patient demonstrated the typical clinical course of posterior reversible encephalopathy syndrome. Conclusion: Hematological malignancy, solid tumor, unrelated donor, and sex-mismatched donor were significant risk factors for HHV-6B infection after pediatric allo-HSCT. In pediatric allo-HSCT patients, the incidence of HHV-6B encephalitis was low and the clinical features differed from those in adult patients.

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  89. Association of Vegetable, Fruit, and Okinawan Vegetable Consumption With Incident Stroke and Coronary Heart Disease. 査読有り

    Yoshizaki T, Ishihara J, Kotemori A, Yamamoto J, Kokubo Y, Saito I, Yatsuya H, Yamagishi K, Sawada N, Iwasaki M, Iso H, Tsugane S, JPHC Study Group.

    Journal of epidemiology   30 巻 ( 1 ) 頁: 37 - 45   2020年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2188/jea.JE20180130

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  90. Cross-sectional association between working and depression prevalence in cancer survivors: a literature review 査読有り 国際誌

    Atsuhiko Ota, Kenji Kawada, Akizumi Tsutsumi, Hiroshi Yatsuya

    Environmental and Occupational Health Practice   2 巻 ( 1 ) 頁: 1 - 10   2020年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1539/eohp.2020-0006-RA

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  91. Association Between Body Mass Index and All-Cause Death in Japanese Population: Pooled Individual Participant Data Analysis of 13 Cohort Studies. 査読有り

    Hozawa A, Hirata T, Yatsuya H, Murakami Y, Kuriyama S, Tsuji I, Sugiyama D, Satoh A, Tanaka-Mizuno S, Miura K, Ueshima H, Okamura T

    Journal of epidemiology   29 巻 ( 12 ) 頁: 457 - 463   2019年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2188/jea.JE20180124

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  92. Seaweed intake and risk of cardiovascular disease: the Japan Public Health Center-based Prospective (JPHC) Study. 査読有り 国際誌

    Murai U, Yamagishi K, Sata M, Kokubo Y, Saito I, Yatsuya H, Ishihara J, Inoue M, Sawada N, Iso H, Tsugane S, JPHC Study Group.

    The American journal of clinical nutrition   110 巻 ( 6 ) 頁: 1449 - 1455   2019年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/ajcn/nqz231

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  93. Diagnostic contribution of cytological examination to endobronchial ultrasound-guided transbronchial biopsy for lung malignancies. 査読有り

    Kajikawa S, Imai N, Okachi S, Yatsuya H, Souma T, Watanabe T, Goto Y, Minezawa T, Hashimoto N, Imaizumi K, Hasegawa Y

    Nagoya journal of medical science   81 巻 ( 4 ) 頁: 613 - 620   2019年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nagoya Journal of Medical Science  

    Although endobronchial ultrasound guided transbronchial biopsy (TBB) with a guide sheath (EBUSGS) is widely used for diagnosis of peripheral pulmonary lesions, the diagnostic contribution of cytology (bronchial brushing, bronchial washing and biopsy forceps rinse) has not been established. To determine the diagnostic contribution of cytological examination to EBUS-GS-TBB, we reviewed medical records of patients with lung malignancies who had undergone TBB with EBUS-GS (EBUS-GS group, n=187) or TBB without EBUS-GS (conventional TBB [CTBB] group, n=197) at Nagoya University Hospital. Although the mean size of target lesions was significantly larger in the CTBB group than the EBUS-GS group, the total diagnostic rate was equivalent between two groups (EBUS-GS: 73.3%, CTBB: 66.0%). In the EBUS-GS group, cytological procedures increased the diagnostic rate by 9.1% (17/137), compared with only 4.1% (8/130) in the CTBB group. Sensitivity of cytology among biopsy-negative patients was significantly higher in EBUS-GS group than CTBB group (P=0.022). Furthermore, in the EBUS-GS group, among 17 patients whose malignant diagnoses could only be established cytologically, bronchial brushing contributed to the malignant diagnosis in 64.7% (11/17). These data may suggest that cytological examination, especially bronchial brushing, may be an important diagnostic contributor in EBUS-GS-TBB.

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  94. The association between weight fluctuation and all-cause mortality: A systematic review and meta-analysis. 査読有り 国際共著 国際誌

    Zhang Y, Hou F, Li J, Yu H, Li L, Hu S, Shen G, Yatsuya H

    Medicine   98 巻 ( 42 ) 頁: e17513   2019年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1097/MD.0000000000017513

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  95. メタボリックシンドローム、空腹時血糖、腹囲身長比による6年後の2型糖尿病発症予測能 査読有り

    金子 佳世, 八谷 寛, 李 媛英, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 青山 温子

    日本公衆衛生学会総会抄録集   78回 巻   頁: 220 - 220   2019年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  96. メタボリックシンドローム、空腹時血糖、腹囲身長比による6年後の2型糖尿病発症予測能

    金子 佳世, 八谷 寛, 李 媛英, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 青山 温子

    日本公衆衛生学会総会抄録集   78回 巻   頁: 220 - 220   2019年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  97. Body Mass Index and Risks of Incident Ischemic Stroke Subtypes: The Japan Public Health Center-Based Prospective (JPHC) Study. 査読有り 国際誌

    Li Y, Yatsuya H, Iso H, Yamagishi K, Saito I, Kokubo Y, Sawada N, Tsugane S

    Journal of epidemiology   29 巻 ( 9 ) 頁: 325 - 333   2019年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Epidemiology  

    Background: The association of body mass index (BMI) with risks of ischemic stroke subtypes have not been established. Methods: Cumulative average BMI was calculated using self-reported body weight and height obtained from baseline (Cohort I in 1990, and Cohort II from 1993-1994) and 5- and 10-year questionnaire surveys of Japan Public Health Center-based prospective (JPHC) study. A total of 42,343 men and 46,413 women aged 40-69 years were followed-up for the incidence of lacunar, large-artery occlusive, and cardioembolic strokes. A sub-distribution hazard model was used to estimate subdistribution hazard ratios (SHRs) and the 95% confidence intervals (CIs). Results: During a median of 20.0 years of follow-up, we documented 809 and 481 lacunar, 395 and 218 large-artery occlusive, and 568 and 298 cardioembolic strokes in men and women, respectively. After adjustment for baseline age, updated smoking, alcohol consumption, leisure-time physical activity, and histories of hypertension, dyslipidemia, and diabetes mellitus, cumulative average BMI was positively linearly associated with lacunar (trend P = 0.007), large-artery occlusive (trend P = 0.002), and cardioembolic (trend P < 0.001) strokes in men, and with lacunar (trend P < 0.001) and large-artery occlusive (trend P = 0.003) strokes in women. There were approximately two-fold excess risk of cardioembolic stroke in both sexes and of lacunar and large-artery occlusive strokes in women for cumulative average BMI ≥30 kg=m2 compared to BMI 23-<25 kg=m2. Conclusion: Cumulative average BMI showed a positive linear effect on sub-distribution hazards of lacunar, large-artery occlusive, and cardioembolic strokes in both sexes, except for cardioembolic stroke in women.

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  98. 労働災害における休業見込期間と実休業日数の差異 労働者死傷病報告と実休業日数との乖離

    加藤 善士, 太田 充彦, 八谷 寛

    労働安全衛生研究   12 巻 ( 3 ) 頁: 173 - 179   2019年9月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:(独)労働者健康安全機構労働安全衛生総合研究所  

    労働基準監督署では,労働災害の重篤度を休業見込期間により判断し,労働災害防止施策を展開している.しかし,労働災害の休業が当初の休業見込期間を超えて長期に及ぶことがある.的確な労働災害防止施策を展開するためには,休業期間を早期に正確に把握することが重要となる.そこで某労働基準監督署管内の過去3年間に発生した労働災害1,672件(男性1,204名,女性468名)について,事業場から報告される労働者死傷病報告と労働者災害補償内容を対比し,休業見込期間と実際の実休業日数の乖離状況を調べ,業種,事業場規模,性別,年齢,業務経験期間,平均賃金との関連を検討した.休業見込期間を超えて実際に休業した者の割合は男性で71.2%,女性で63.9%であった.休業見込期間(中央値:男性30日,女性28日)と実休業日数(中央値:男性50日,女性39日)は男性の方が長かった.休業見込期間を超えて休業する者の割合は,男性において事業場業種,事業場規模,年齢で有意な差が認められた.また,実休業日数/休業見込期間比の中央値は男性1.38,女性1.20と男女間で有意な差があった.労働災害の重篤度を休業見込期間で判断することは,重篤度を過小評価する可能性が高く,実休業日数が休業見込期間を超える割合には,男女で差があった.(著者抄録)

    DOI: 10.2486/josh.JOSH-2019-0009-CHO

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2019&ichushi_jid=J05150&link_issn=&doc_id=20191002450005&doc_link_id=10.2486%2Fjosh.JOSH-2019-0009-CHO&url=https%3A%2F%2Fdoi.org%2F10.2486%2Fjosh.JOSH-2019-0009-CHO&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  99. エチオピア北部の公務員における糖尿病および前糖尿病の危険因子(Risk factors of diabetes and prediabetes among public employees in northern Ethiopia) 国際共著

    He Yupeng, Chiang Chifa, Gebremariam Lemlem W., Yatsuya Hiroshi, Hirakawa Yoshihisa, Aoyama Atsuko

    国際保健医療   34 巻 ( 3 ) 頁: 140 - 141   2019年9月

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    記述言語:英語   掲載種別:研究論文(その他学術会議資料等)   出版者・発行元:(一社)日本国際保健医療学会  

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  100. High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver. 査読有り 国際誌

    Naito H, Yoshikawa-Bando Y, Yuan Y, Hashimoto S, Kitamori K, Yatsuya H, Nakajima T

    Scientific reports   9 巻 ( 1 ) 頁: 12514 - 12514   2019年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Scientific Reports  

    Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC) diet, we aimed to clarify the roles of autophagy and endoplasmic reticulum (ER) stress in NASH progression. Male SHRSP5/Dmcr were randomly divided into 4 groups. Two groups were fed a control diet; the other two groups were fed a HFC diet for 2 and 8 weeks, respectively. The HFC diet increased the autophagy-related proteins levels and microtubule-associated protein 1 light chain 3-II/I ratio after 2 and 8 weeks, respectively. However, regarding ER stress-related proteins, the HFC diet decreased the levels of phosphorylated (p-) inositol-requiring kinase-1 (p-IRE-1) and p-protein kinase RNA-like ER kinase after 2 weeks. Additionally, the HFC diet increased anti-ubiquitin-positive cells and the level of the autophagy substrate p62, suggesting that the HFC diet induced dysfunction in ubiquitin-dependent protein degradation pathways. In conclusion, the HFC diet arrested the autophagy process in the liver; this was particularly associated with decreases in p-IRE-1 expression.

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  101. Automated Feedback Messages With Shichifukujin Characters Using IoT System-Improved Glycemic Control in People With Diabetes: A Prospective, Multicenter Randomized Controlled Trial. 査読有り 国際誌

    Kobayashi T, Tsushita K, Nomura E, Muramoto A, Kato A, Eguchi Y, Onoue T, Goto M, Muto S, Yatsuya H, Arima H

    Journal of diabetes science and technology   13 巻 ( 4 ) 頁: 796 - 798   2019年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Diabetes Science and Technology  

    DOI: 10.1177/1932296819851785

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  102. Associations of Daily Walking Time With Pneumonia Mortality Among Elderly Individuals With or Without a Medical History of Myocardial Infarction or Stroke: Findings From the Japan Collaborative Cohort Study. 査読有り 国際誌

    Ukawa S, Zhao W, Yatsuya H, Yamagishi K, Tanabe N, Iso H, Tamakoshi A

    Journal of epidemiology   29 巻 ( 6 ) 頁: 233 - 237   2019年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Epidemiology  

    Background: The association between daily walking and pneumonia mortality, stratified by the presence of disease conditions, such as myocardial infarction (MI) or stroke, was investigated. Methods: The study participants were 22,280 Japanese individuals (9,067 men and 13,213 women) aged 65-79 years. Inverse propensity weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for pneumonia mortality. Results: After a median of 11.9 years of follow-up, 1,203 participants died of pneumonia. Participants who did not have a history of MI or stroke and who walked for 1 hour=day or more were less likely to die from pneumonia (HR 0.90; 95% CI, 0.82-0.98) than those walked for 0.5 hours=day. A similar inverse association of pneumonia and walking (0.5 hours=day) was observed among participants with a history of MI (HR 0.66; 95% CI, 0.48-0.90). Among the participants with a history of stroke, those who walked for 0.6-0.9 hours=day were less likely to die because of pneumonia (HR 0.65; 95% CI, 0.43-0.98). Conclusions: Regular walking for?1 hour=day may reduce the risk of pneumonia mortality in elderly individuals with or without cardiovascular disease history.

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  103. Socioeconomic and lifestyle factors associated with depressive tendencies in general Japanese men and women: NIPPON DATA2010. 査読有り 国際誌

    Suzuki H, Kadota A, Okuda N, Hayakawa T, Nishi N, Nakamura Y, Arima H, Miyagawa N, Satoh A, Miyamatsu N, Yanagita M, Yatsuya H, Yamagata Z, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K, NIPPON DATA2010 Research Group.

    Environmental health and preventive medicine   24 巻 ( 1 ) 頁: 37 - 37   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s12199-019-0788-6

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  104. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 査読有り 国際共著 国際誌

    Johnson C.O., Nguyen M., Roth G.A., Nichols E., Alam T., Abate D., Abd-Allah F., Abdelalim A., Abraha H.N., Abu-Rmeileh N.M., Adebayo O.M., Adeoye A.M., Agarwal G., Agrawal S., Aichour A.N., Aichour I., Aichour M.T.E., Alahdab F., Ali R., Alvis-Guzman N., Anber N.H., Anjomshoa M., Arabloo J., Arauz A., Ärnlöv J., Arora A., Awasthi A., Banach M., Barboza M.A., Barker-Collo S.L., Bärnighausen T.W., Basu S., Belachew A.B., Belayneh Y.M., Bennett D.A., Bensenor I.M., Bhattacharyya K., Biadgo B., Bijani A., Bikbov B., Bin Sayeed M.S., Butt Z.A., Cahuana-Hurtado L., Carrero J.J., Carvalho F., Castañeda-Orjuela C.A., Castro F., Catalá-López F., Chaiah Y., Chiang P.P.C., Choi J.Y.J., Christensen H., Chu D.T., Cortinovis M., Damasceno A.A.M., Dandona L., Dandona R., Daryani A., Davletov K., De Courten B., De la Cruz-Góngora V., Degefa M.G., Dharmaratne S.D., Diaz D., Dubey M., Duken E.E., Edessa D., Endres M., Faraon E.J.A., Farzadfar F., Fernandes E., Fischer F., Flor L.S., Ganji M., Gebre A.K., Gebremichael T.G., Geta B., Gezae K.E., Gill P.S., Gnedovskaya E.V., Gómez-Dantés H., Goulart A.C., Grosso G., Guo Y., Gupta R., Haj-Mirzaian A., Haj-Mirzaian A., Hamidi S., Hankey G.J., Hassen H.Y., Hay S.I., Hegazy M.I., Heidari B., Herial N.A., Hosseini M.A., Hostiuc S., Irvani S.S.N., Islam S.M.S., Jahanmehr N., Javanbakht M.

    The Lancet Neurology   18 巻 ( 5 ) 頁: 439 - 458   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Lancet Neurology  

    Background: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. Methods: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, prevalence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs). DALYs were generated by summing YLLs and YLDs. Cause-specific mortality was estimated using an ensemble modelling process with vital registration and verbal autopsy data as inputs. Non-fatal estimates were generated using Bayesian meta-regression incorporating data from registries, scientific literature, administrative records, and surveys. The Socio-demographic Index (SDI), a summary indicator generated using educational attainment, lagged distributed income, and total fertility rate, was used to group countries into quintiles. Findings: In 2016, there were 5·5 million (95% UI 5·3 to 5·7) deaths and 116·4 million (111·4 to 121·4) DALYs due to stroke. The global age-standardised mortality rate decreased by 36·2% (−39·3 to −33·6) from 1990 to 2016, with decreases in all SDI quintiles. Over the same period, the global age-standardised DALY rate declined by 34·2% (−37·2 to −31·5), also with decreases in all SDI quintiles. There were 13·7 million (12·7 to 14·7) new stroke cases in 2016. Global age-standardised incidence declined by 8·1% (−10·7 to −5·5) from 1990 to 2016 and decreased in all SDI quintiles except the middle SDI group. There were 80·1 million (74·1 to 86·3) prevalent cases of stroke globally in 2016; 41·1 million (38·0 to 44·3) in women and 39·0 million (36·1 to 42·1) in men. Interpretation: Although age-standardised mortality rates have decreased sharply from 1990 to 2016, the decrease in age-standardised incidence has been less steep, indicating that the burden of stroke is likely to remain high. Planned updates to future GBD iterations include generating separate estimates for subarachnoid haemorrhage and intracerebral haemorrhage, generating estimates of transient ischaemic attack, and including atrial fibrillation as a risk factor. Funding: Bill & Melinda Gates Foundation

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  105. Association of gamma-glutamyl transferase and alanine aminotransferase with type 2 diabetes mellitus incidence in middle-aged Japanese men: 12-year follow up. 査読有り

    Kaneko K, Yatsuya H, Li Y, Uemura M, Chiang C, Hirakawa Y, Ota A, Tamakoshi K, Aoyama A

    Journal of diabetes investigation   10 巻 ( 3 ) 頁: 837 - 845   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Diabetes Investigation  

    Aims/Introduction: To prospectively investigate whether simultaneous elevation of gamma-glutamyl transferase (GGT) and alanine aminotransferase (ALT) is associated with the increase of type 2 diabetes mellitus incidence independent of alcohol drinking, body mass index and triglycerides. Methods: A total of 2,775 Japanese male workers who had no history of type 2 diabetes mellitus were followed. High GGT and ALT were defined as the top tertiles (GGT cutpoint: 49 IU/L, ALT cutpoint: 28 IU/L). Three groups were created using these dichotomized GGT and ALT cutpoints: both low, either high or both high. Multivariable Cox proportional hazards models were carried out adjusted for potential confounding factors. Results: A total of 276 type 2 diabetes mellitus cases were identified during 12 years (27,040 person-years) of follow up. Participants with simultaneously elevated GGT and ALT had a significantly higher incidence of type 2 diabetes mellitus, even after adjustment for fasting insulin and fasting blood glucose compared with the group without GGT or ALT elevation. Similar associations were observed in non- or light-to-moderate alcohol drinkers, as well as in participants with normal weight. However, the association was weaker in participants with triglycerides <150 mg/dL. We then evaluated whether the addition of GGT and ALT would improve the prediction of type 2 diabetes mellitus incidence, and found that their inclusion significantly increased the C-statistic, net reclassification improvement and integrated discrimination improvement. Conclusions: Simultaneous elevation of GGT and ALT was significantly associated with type 2 diabetes mellitus incidence, independent of potential confounding factors, including alcohol drinking and obesity, although the association might require concomitant elevation of triglycerides. Inclusion of GGT and ALT improved type 2 diabetes mellitus risk prediction.

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  106. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 査読有り 国際共著 国際誌

    Feigin V.L., Nichols E., Alam T., Bannick M.S., Beghi E., Blake N., Culpepper W.J., Dorsey E.R., Elbaz A., Ellenbogen R.G., Fisher J.L., Fitzmaurice C., Giussani G., Glennie L., James S.L., Johnson C.O., Kassebaum N.J., Logroscino G., Marin B., Mountjoy-Venning W.C., Nguyen M., Ofori-Asenso R., Patel A.P., Piccininni M., Roth G.A., Steiner T.J., Stovner L.J., Szoeke C.E.I., Theadom A., Vollset S.E., Wallin M.T., Wright C., Zunt J.R., Abbasi N., Abd-Allah F., Abdelalim A., Abdollahpour I., Aboyans V., Abraha H.N., Acharya D., Adamu A.A., Adebayo O.M., Adeoye A.M., Adsuar J.C., Afarideh M., Agrawal S., Ahmadi A., Ahmed M.B., Aichour A.N., Aichour I., Aichour M.T.E., Akinyemi R.O., Akseer N., Al-Eyadhy A., Al-Shahi Salman R., Alahdab F., Alene K.A., Aljunid S.M., Altirkawi K., Alvis-Guzman N., Anber N.H., Antonio C.A.T., Arabloo J., Aremu O., Ärnlöv J., Asayesh H., Asghar R.J., Atalay H.T., Awasthi A., Ayala Quintanilla B.P., Ayuk T.B., Badawi A., Banach M., Banoub J.A.M., Barboza M.A., Barker-Collo S.L., Bärnighausen T.W., Baune B.T., Bedi N., Behzadifar M., Behzadifar M., Béjot Y., Bekele B.B., Belachew A.B., Bennett D.A., Bensenor I.M., Berhane A., Beuran M., Bhattacharyya K., Bhutta Z.A., Biadgo B., Bijani A., Bililign N., Bin Sayeed M.S., Blazes C.K., Brayne C., Butt Z.A., Campos-Nonato I.R., Cantu-Brito C., Car M.

    The Lancet Neurology   18 巻 ( 5 ) 頁: 459 - 480   2019年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Lancet Neurology  

    Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. Methods: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach. Findings: Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable). Interpretation: Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies. Funding: Bill & Melinda Gates Foundation.

    DOI: 10.1016/S1474-4422(18)30499-X

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  107. 特定保健指導レベルと2型糖尿病発症の関連・その臨床疫学的指標 愛知職域コホート

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 内藤 久雄, 太田 充彦, 玉腰 浩司, 青山 温子

    産業衛生学雑誌   61 巻 ( 臨増 ) 頁: 321 - 321   2019年5月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  108. トリクロロエチレンによるCYP2E1抗体上昇とhypersensitivity syndromeとの関係

    那須 民江, 王 海蘭, 袁 媛, 内藤 久雄, 伊藤 由起, 八谷 寛, 上島 通浩

    産業衛生学雑誌   61 巻 ( 臨増 ) 頁: 332 - 332   2019年5月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  109. Working Hours and Risk of Acute Myocardial Infarction and Stroke Among Middle-Aged Japanese Men - The Japan Public Health Center-Based Prospective Study Cohort II. 査読有り

    Hayashi R, Iso H, Yamagishi K, Yatsuya H, Saito I, Kokubo Y, Eshak ES, Sawada N, Tsugane S, Japan Public Health Center-Based (JPHC) Prospective Study Group.

    Circulation journal : official journal of the Japanese Circulation Society   83 巻 ( 5 ) 頁: 1072 - 1079   2019年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1253/circj.CJ-18-0842

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  110. Recent Status and Methodological Quality of Return-to-Work Rates of Cancer Patients Reported in Japan: A Systematic Review. 査読有り 国際誌

    Ota A, Fujisawa A, Kawada K, Yatsuya H

    International journal of environmental research and public health   16 巻 ( 8 )   2019年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/ijerph16081461

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  111. Validation of the Japanese Version of the Yale Food Addiction Scale 2.0 (J-YFAS 2.0). 査読有り 国際共著

    Khine MT, Ota A, Gearhardt AN, Fujisawa A, Morita M, Minagawa A, Li Y, Naito H, Yatsuya H

    Nutrients   11 巻 ( 3 ) 頁: 687 - 687   2019年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/nu11030687

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  112. Multicenter feasibility study of bowel preparation with castor oil for colon capsule endoscopy 査読有り 国際誌

    Ohmiya Naoki, Hotta Naoki, Mitsufuji Shoji, Nakamura Masanao, Omori Takafumi, Maeda Kohei, Okuda Kotaro, Yatsuya Hiroshi, Tajiri Hisao

    DIGESTIVE ENDOSCOPY   31 巻 ( 2 ) 頁: 164 - 172   2019年3月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Digestive Endoscopy  

    Background and Aim: Extensive use of laxatives and incomplete excretion rates are problematic for colon capsule endoscopy (CCE). The aim of the present study was to determine the effectiveness of castor oil as a booster. Methods: At four Japanese hospitals, 319 examinees undergoing CCE were enrolled retrospectively. Before and after the introduction of castor oil, other preparation reagents were unchanged. Results: Of 319 examinees who underwent CCE, 152 and 167 examinees took regimens with castor oil (between November 2013 and June 2016) and without castor oil (between October 2015 and September 2017), respectively. Capsule excretion rates within its battery life in the groups with and without castor oil were 97% and 81%, respectively (P < 0.0001). Multivariate analysis showed that ages younger than 65 years (adjusted odds ratio [OR], 3.00; P = 0.0048), male gender (adjusted OR, 3.20; P = 0.0051), and use of castor oil (adjusted OR, 6.29; P = 0.0003) were predictors of capsule excretion within its battery life. Small bowel transit time was shorter and total volume of lavage and fluid intake was lower with castor oil than without (P = 0.0154 and 0.0013, respectively). Overall adequate cleansing level ratios with and without castor oil were 74% and 83%, respectively (P = 0.0713). Per-examinee sensitivity for polyps ≥6 mm with and without castor oil was 83% and 85%, respectively, with specificities of 80% and 78%, respectively. Conclusion: Bowel preparation with castor oil was effective for improving capsule excretion rate and reducing liquid loading.

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  113. Prevalence and Correlates of Dyslipidemia Among Men and Women in Palau: Findings of the Palau STEPS Survey 2011-2013 査読有り 国際共著 国際誌

    Cui Meishan, Chiang Chifa, Cui Renzhe, Honjo Kaori, Yatsuya Hiroshi, Watson Berry Moon, Ikerdeu Edolem, Mita Takashi, Madraisau Sherilynn, Aoyama Atsuko, Iso Hiroyasu

    JOURNAL OF EPIDEMIOLOGY   29 巻 ( 3 ) 頁: 97 - 103   2019年3月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Epidemiology  

    Background: Epidemiological evidence of dyslipidemia in Pacific Island countries is limited despite the knowledge that non-communicable diseases have a high burden in the region. We aimed to examine the prevalence and correlates of dyslipidemia among residents of Palau. Methods: The Palau STEPwise approach to Surveillance (STEPS), which was conducted from 2011 through 2013, comprised three parts: behavioral risk factors; physical measurements; and biochemical tests, covering areas such as blood lipids. We used STEPS-generated data to perform a cross-sectional study of 2,184 randomly selected Palau residents, comprising Palauans and non-Palauans aged 25–64 years. Results: The age-adjusted mean BMI was 29.3 kg/m 2 in men and 29.9 kg/m 2 in women; age-adjusted mean triglycerides value was 182 mg/dL in men and 166 mg/dL in women; and age-adjusted mean cholesterol was 178 mg/dL in men and 183 mg/dL in women. The prevalence of overweight/obesity (BMI ≥25 kg/m 2 ) was 75% in men and 76% in women, and those of hypertriglyceridemia (triglycerides ≥150 mg/dL) and hypercholesterolemia (total cholesterol ≥200 mg/dL) were 48% in men and 41% in women and 18% in men and 23% in women, respectively. Mean values of total cholesterol were 177 mg/dL in Palauan men and 182 mg/dL in non-Palauan men. Mean values of triglycerides were 171 mg/dL in Palauan women and 150 mg/dL in non-Palauan women. Women living in rural areas showed a higher mean value of total cholesterol than those in urban areas. Conclusion: We found a high mean BMI and high prevalence of overweight/obesity and hypertriglyceridemia, but low mean total cholesterol and a low prevalence of hypercholesterolemia in Palau. Lipid profiles varied by age, ethnicity, and living area.

    DOI: 10.2188/jea.JE20170127

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  114. Sleep duration and risk of breast cancer: The JACC Study

    Cao Jinhong, Eshak Ehab S., Liu Keyang, Muraki Isao, Cui Renzhe, Iso Hiroyasu, Tamakoshi Akiko, Tamakoshi Akiko, Mori Mitsuru, Kaneko Yoshihiro, Tsuji Ichiro, Nakamura Yosikazu, Yamagishi Kazumasa, Mikami Haruo, Kurosawa Michiko, Hoshiyama Yoshiharu, Tanabe Naohito, Tamakoshi Koji, Wakai Kenji, Tokudome Shinkan, Suzuki Koji, Hashimoto Shuji, Yatsuya Hiroshi, Kikuchi Shogo, Wada Yasuhiko, Kawamura Takashi, Watanabe Yoshiyuki, Ozasa Kotaro, Mikami Kazuya, Date Chigusa, Sakata Kiyomi, Kurozawa Yoichi, Yoshimura Takesumi, Fujino Yoshihisa, Shibata Akira, Okamoto Naoyuki, Shio Hideo

    BREAST CANCER RESEARCH AND TREATMENT   174 巻 ( 1 ) 頁: 219-225   2019年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10549-018-4995-4

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  115. Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium 査読有り 国際共著 国際誌

    Inker Lesley A., Grams Morgan E., Levey Andrew S., Coresh Josef, Cirillo Massimo, Collins John F., Gansevoort Ron T., Gutierrez Orlando M., Hamano Takayuki, Heine Gunnar H., Ishikawa Shizukiyo, Jee Sun Ha, Kronenberg Florian, Landray Martin J., Miura Katsuyuki, Nadkarni Girish N., Peralta Carmen A., Rothenbacher Dietrich, Schaeffner Elke, Sedaghat Sanaz, Shlipak Michael G., Zhang Luxia, van Zuilen Arjan D., Hallan Stein I, Kovesdy Csaba P., Woodward Mark, Levin Adeera, Astor Brad, Appel Lawrence J., Greene Tom, Chen Teresa K., Chalmers John, Arima Hisatomi, Perkovic Vlado, Yatsuya Hiroshi, Tamakoshi Koji, Li Yuanying, Hirakawa Yoshihisa, Matsushita Kunihiro, Grams Morgan, Sang Yingying, Polldnghorne Kevan, Chadban Steven, Atkins Robert, Djurdjev Ognjenka, Liu Lisheng, Zhao Ming-hui, Wang Fang, Wang Jinwei, Ebert Natalie, Martus Peter, Tang Mila, Heine Gunnar, Emrich Insa, Seiler Sarah, Zawada Adam, Nally Joseph, Navaneethan Sankar D., Schold Jesse D., Zhao Minghui, Sarnak Mark J., Katz Ronit, Hiramoto Jade, Iso Hiroyasu, Yamagishi Kazumasa, Umesawa Mitsumasa, Murald Isao, Fukagawa Masafumi, Maruyama Shoichi, Hasegawa Takeshi, Fujii Naohiko, Wheeler David C., Emberson Jonathan, Townend John, Landray Martin, Brenner Hermann, Schottker Ben, Saum Kai-Uwe, Fox Caroline, Hwang Shih-Jen, Kottgen Anna, Schneider Markus P., Eckardt Kai-Uwe, Green Jamie A., Kirchner H. Lester, Chang Alex R., Ho Kevin, Ito Sadayoshi, Miyazaki Mariko, Nakayama Masaaki, Yamada Gen, Irie Fujiko, Sairenchi Toshimi, Yano Yuichiro, Kotani Kazuhiko, Nakamura Takeshi, Kimm Heejin, Mok Yejin, Chodick Gabriel, Shalev Varda, Wetzels Jack F. M., Blankestijn Peter J., van den Brand Jan A., Sarnak Mark, Peralta Carmen, Kollerits Barbara, Ritz Eberhard, Nitsch Dorothea, Roderick Paul, Fletcher Astrid, Bottinger Erwin, Ellis Stephen B., Nadukuru Rajiv, Ueshima Hirotsugu, Okayama Akira, Miura Katsuyuld, Tanaka Sachiko, Okamura Tomonori, Kadota Aya, Kenealy Timothy, Elley C. Raina, Drury Paul L., Ohkubo Takayoshi, Asayama Kei, Metold Hirohito, Kikuya Masahiro, Nelson Robert G., Knowler William C., Bakker Stephan J. L., Hak Eelco, Heerspink Hiddo J. L., Brunskill Nigel J., Major Rupert W., Shepherd David, Medcalf James F., Bernardo Rancho, Jassal Simerjot K., Bergstrom Jaclyn, Ix Joachim H., Barrett-Connor Elizabeth, Kalantar-Zadeh Kamyar, Sumida Keiichi, Muntner Paul, Warnock David, McClellan William, de Zeeuw Dick, Brenner Barry, Ikram M. Arfan, Hoorn Ewout J., Dehghan Abbas, Carrero Juan J., Gasparini Alessandro, Wettermark Bjorn, Elinder Carl-Gustaf, Wong Tien Yin, Sabanayagam Charumathi, Cheng Ching-Yu, Sokor Riswana Banu Binte Mohamed Abdul, Visseren Frank L. J., Evans Marie, Segelmark Marten, Stendahl Maria, Schon Staffan, Tangri Navdeep, Sud Maneesh, Naimark David M., Wen Chi-Pang, Tsao Chwen-Keng, Tsai Min-Kugng, Chen Chien-Hua, Konta Tsuneo, Hirayama Atsushi, Ichikawa Kazunobu, Lannfelt Lars, Larsson Anders, Arnlov Johan, Bilo Henk J. G., Landman Gijs W. D., van Hateren Kornelis J. J., Kleefstra Nanne, Hallan Stein, Ballew Shoshana H., Chen Jingsha, Kwak Lucia, Surapaneni Aditya

    AMERICAN JOURNAL OF KIDNEY DISEASES   73 巻 ( 2 ) 頁: 206 - 217   2019年2月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1053/j.ajkd.2018.08.013

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    その他リンク: http://orcid.org/0000-0002-3283-8196

  116. Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium

    Chang Alex R., Grams Morgan E., Ballew Shoshana H., Bilo Henk, Correa Adolfo, Evans Marie, Gutierrez Orlando M., Hosseinpanah Farhad, Iseki Kunitoshi, Kenealy Timothy, Klein Barbara, Kronenberg Florian, Lee Brian J., Li Yuanying, Miura Katsuyuki, Navaneethan Sankar D., Roderick Paul J., Valdivielso Jose M., Visseren Frank L. J., Zhang Luxia, Gansevoort Ron T., Hallan Stein I., Levey Andrew S., Matsushita Kunihiro, Shalev Varda, Woodward Mark, Astor Brad, Appel Larry, Greene, Chen Teresa, Chalmers John, Woodward Mark, Arima Hisatomi, Perkovic Vlado, Yatsuya Hiroshi, Tamakoshi Koji, Li Yuanying, Hirakawa Yoshihisa, Coresh Josef, Matsushita Kunihiro, Grams Morgan, Sang Yingying, Polkinghorne Kevan, Chadban Steven, Atkins Robert, Levin Adeera, Djurdjev Ognjenka, Dam Beaver, Klein Ron, Klein Barbara, Lee Kristine, Zhang Luxia, Liu Lisheng, Zhao Minghui, Wang Fang, Wang Jinwei, Levin Adeera, Djurdjev Ognjenka, Tang Mila, Heine Gunnar, Emrich Insa, Zawada Adam, Bauer Lucie, Nally Joseph, Navaneethan Sankar, Schold Jesse, Zhang Luxia, Zhao Minghui, Wang Fang, Wang Jinwei, Shlipak Michael, Sarnak Mark, Katz Ronit, Hiramoto Jade, Iso Hiroyasu, Yamagishi Kazumasa, Umesawa Mitsumasa, Muraki Isao, Fukagawa Masafumi, Maruyama Shoichi, Hamano Takayuki, Hasegawa Takeshi, Fujii Naohiko, Jafar Tazeen, Hatcher Juanita, Poulter Neil, Chaturvedi Nish, Wheeler David, Emberson John, Townend John, Landray Martin, Hermann, Brenner, Schottker Ben, Saum Kai-Uwe, Rothenbacher Dietrich, Fox Caroline, Hwang Shih-Jen, Kottgen Anna, Kronenberg Florian, Schneider Markus P., Eckardt Kai-Uwe, Green Jamie, Kirchner H. Lester, Chang Alex R., Ito Sadayoshi, Miyazaki Mariko, Nakayama Masaaki, Yamada Gen, Cirillo Massimo, Hallan Stein, Romundstad Solfrid, Ovrehus Marius, Langlo Knut Asbjorn, Irie Fujiko, Sairenchi Toshimi, Correa Adolfo, Rebholz Casey M., Young Bessie, Boulware L. Ebony, Ishikawa Shizukiyo, Yano Yuichiro, Kotani Kazuhiko, Nakamura Takeshi, Jee Sun Ha, Kimm Heejin, Mok Yejin, Lee Brian J., Chodick Gabriel, Shalev Varda, Wetzels Jack F. M., Blankestijn Peter J., van Zuilen Arjan D., Bots M., Sarnak Mark, Inker Lesley, Shlipak Michael, Sarnak Mark, Katz Ronit, Peralta Carmen, Kronenberg Florian, Kollerits Barbara, Ritz Eberhard, Nitsch Dorothea, Roderick Paul, Fletcher Astrid, Bottinger Erwin, Nadkarni Girish N., Ellis Stephen B., Nadukuru Rajiv, Valdivielso Jose M., Fernandez Elvira, Betriu Angels, Bermudez-Lopez Marcelino, Stengel Benedicte, Metzger Marie, Flamant Martin, Houillier Pascal, Haymann Jean-Philippe, Froissart Marc, Sang Yingying, Ueshima Hirotsugu, Okayama Akira, Miura Katsuyuki, Tanaka Sachiko, Ueshima Hirotsugu, Okamura Tomonori, Miura Katsuyuki, Tanaka Sachiko, Kenealy Timothy, Elley C. Raina, Collins John F., Drury Paul L., Ohkubo Takayoshi, Asayama Kei, Metoki Hirohito, Kikuya Masahiro, Nakayama Masaaki, Iseki Kunitoshi, Iseki Chiho, Nelson Robert G., Knowler William C., Gansevoort Ron T., Bakker Stephan J. L., Heerspink Hiddo J. L., Brunskill Nigel, Major Rupert, Shepherd David, Medcalf James, Bernardo Rancho, Jassal Simerjot K., Bergstrom Jaclyn, Joachim H., Barrett-Connor Elizabeth, Kovesdy Csaba, Kalantar-Zadeh Kamyar, Sumida Keiichi, Muntner Paul, Warnock David, Judd Suzanne, Panwar Bhupesh, Heerspink Hiddo J. L., de Zeeuw Dick, Brenner Barry, Sedaghat Sanaz, Ikram M. Arfan, Hoorn Ewout J., Dehghan Abbas, Wong Tien Yin, Sabanayagam Charumathi, Cheng Ching-Yu, Binte Riswana Banu, Sokor Mohamed Abdul, Visseren Frank L. J., Evans Marie, Segelmark Marten, Stendahl Maria, Schon Staffan, Tangri Navdeep, Sud Maneesh, Naimark David, Wen Chi-Pang, Tsao Keng, Tsai Min-Kugng, Chen Chien-Hua, Konta Tsuneo, Hirayama Atsushi, Ichikawa Kazunobu, Hosseinpanah Farhad, Hadaegh Farzad, Mirbolouk Mohammadhassan, Azizi Fereidoun, Solbu Marit Dahl, Jenssen Trond Geir, Eriksen Bjorn Odvar, Eggen Anne Elise, Lannfelt Lars, Larsson Anders, Arnlov Johan, Bilo Henk J. G., Landman Gijs W. D., Van Hateren Kornelis J. J., Kleefstra Nanne, Coresh Josef, Gansevoort Ron T., Grams Morgan E., Hallan Stein, Kovesdy Csaba P., Levey Andrew S., Matsushita Kunihiro, Shalev Varda, Woodward. Mark, Ballew Shoshana H., Chen Jingsha, Coresh Josef, Grams Morgan E., Kwak Lucia, Matsushita Kunihiro, Sang Yingying, Surapaneni Aditya, Woodward Mark

    BMJ-BRITISH MEDICAL JOURNAL   364 巻   2019年1月

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    記述言語:日本語  

    DOI: 10.1136/bmj.k5301

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  117. Lifetime Risk of Stroke and Coronary Heart Disease Deaths According to Blood Pressure Level: EPOCH-JAPAN (Evidence for Cardiovascular Prevention From Observational Cohorts in Japan) 国際誌

    Satoh Michihiro, Ohkubo Takayoshi, Asayama Kei, Murakami Yoshitaka, Sugiyama Daisuke, Yamada Michiko, Saitoh Shigeyuki, Sakata Kiyomi, Irie Fujiko, Sairenchi Toshimi, Ishikawa Shizukiyo, Kiyama Masahiko, Ohnishi Hirofumi, Miura Katsuyuki, Imai Yutaka, Ueshima Hirotsugu, Okamura Tomonori, Iso Hiroyasu, Kitamura Akihiko, Ninomiya Toshiharu, Kiyohara Yutaka, Nakagawa Hideaki, Nakayama Takeo, Okayama Akira, Sairenchi Toshimi, Tamakoshi Akiko, Tsuji Ichiro, Miyamoto Yoshihiro, Ishikawa Shizukiyo, Yatsuya Hiroshi, Okamura Tomonori

    HYPERTENSION   73 巻 ( 1 ) 頁: 52 - 59   2019年1月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1161/HYPERTENSIONAHA.118.11635

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  118. Smoking results in accumulation of ectopic fat in the liver. 査読有り 国際誌

    Kato A, Li Y, Ota A, Naito H, Yamada H, Nihashi T, Hotta Y, Chiang C, Hirakawa Y, Aoyama A, Tamakoshi K, Yatsuya H

    Diabetes, metabolic syndrome and obesity : targets and therapy   12 巻   頁: 1075 - 1080   2019年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy  

    Objective: An association between smoking and nonalcoholic fatty liver disease has been reported. However, objective quantification of intrahepatic fat via magnetic resonance spectroscopy (MRS) in relation to smoking has rarely been performed in previous studies. Moreover, the possible pathways via which smoking could induce ectopic fat accumulation have not yet been addressed. The current study aimed to examine the association between smoking status and intrahepatic fat quantity and explore the possible mediating effects of triglycerides (TG) and adiponectin. Subjects and methods: Magnetic resonance imager (MRI) spectra were analyzed to quantify intrahepatic fat in 45 men who were on average 62.3 years of age. Smoking status and alcohol intake were self-reported. Accelerometers were used to record daily total physical activity. Fasting blood TG and adiponectin levels were measured enzymatically. Differences in mean intrahepatic fat values according to smoking status were assessed using analysis of covariance. Results: A stepwise increase in mean intrahepatic fat was observed between never, former, and current smokers, respectively, independent of age, physical activity, alcohol intake, and body mass index (BMI) (P=0.005). Adjustment for TG and adiponectin significantly attenuated this association (P=0.074). Conclusion: Current smoking was significantly associated with increased intrahepatic fat, which may be a result of adipocyte dysfunction, manifested as high circulating TG concentrations and low adiponectin levels.

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  119. Self-reported eczema in relation with mortality from cardiovascular disease in Japanese: The Japan collaborative cohort study

    Nishida Y., Kubota Y., Iso H., Tamakoshi A., Tamakoshi A., Mori M., Kaneko Y., Tsuji I., Nakamura Y., Iso H., Yamagishi K., Mikami H., Kurosawa M., Hoshiyama Y., Tanabe N., Tamakoshi K., Wakai K., Ando M., Suzuki K., Hashimoto S., Yatsuya H., Kikuchi S., Wada Y., Kawamura T., Watanabe Y., Ozasa K., Mikami K., Date C., Sakata K., Kurozawa Y., Fujino Y., Shibata A.

    Journal of Atherosclerosis and Thrombosis   26 巻 ( 9 ) 頁: 775 - 782   2019年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Atherosclerosis and Thrombosis  

    Aim: Previous studies suggested a positive association between eczema and cardiovascular disease (CVD), probably through enhanced systemic inflammation. However, several studies reported null findings about eczema and CVD, so the evidence is still controversial. Methods: We asked 85,099 participants (35,489 men and 49,610 women), aged 40 to 79 years, without a history of CVD or cancer at baseline between 1988 and 1990, to complete a lifestyle questionnaire, including information eczema frequency (seldom, sometimes or often). Results: During the 6,389,818 person-years of follow-up, there were 1,174 deaths from coronary heart disease (CHD), 979 from heart failure, 366 from cardiac arrhythmia, 2,454 from total stroke, 1,357 from ischemic stroke, 1,013 from hemorrhagic stroke, and 201 from aortic aneurysm or dissection. The multivariable-adjusted model showed that individuals who “sometimes” or “often” had eczema had 0.82 (95%confidence interval (CI): 0.69–0.97) or 1.26 (95%CI: 1.01–1.56) times the risk of mortality from CHD, respectively, compared to those who “seldom” did. Individuals who “often” had 1.30 (95%CI: 1.05–1.61) times the risk of mortality from CHD, compared to those who “seldom or sometimes” did. There was no association of eczema with mortality from other CVD, or no interaction between eczema and sex or age, in relation to any CVD mortality risk. Conclusions: Self-reported frequent eczema was associated with increased risk of mortality from CHD, but not other major CVD, in a Japanese general population. Since steroid usage was not considered, future studies should include it as a potential confounding factor.

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  120. Comparing different definitions of prediabetes with subsequent risk of diabetes: an individual participant data meta-analysis involving 76 513 individuals and 8208 cases of incident diabetes. 査読有り 国際共著 国際誌

    Lee CMY, Colagiuri S, Woodward M, Gregg EW, Adams R, Azizi F, Gabriel R, Gill TK, Gonzalez C, Hodge A, Jacobs Jr DR Jr, Joseph JJ, Khalili D, Magliano DJ, Mehlig K, Milne R, Mishra G, Mongraw-Chaffin M, Pasco JA, Sakurai M, Schreiner PJ, Selvin E, Shaw JE, Wittert G, Yatsuya H, Huxley RR

    BMJ open diabetes research & care   7 巻 ( 1 ) 頁: e000794   2019年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMJ Open Diabetes Research and Care  

    Objective There are currently five widely used definition of prediabetes. We compared the ability of these to predict 5-year conversion to diabetes and investigated whether there were other cut-points identifying risk of progression to diabetes that may be more useful. Research design and methods We conducted an individual participant meta-analysis using longitudinal data included in the Obesity, Diabetes and Cardiovascular Disease Collaboration. Cox regression models were used to obtain study-specific HRs for incident diabetes associated with each prediabetes definition. Harrell's C-statistics were used to estimate how well each prediabetes definition discriminated 5-year risk of diabetes. Spline and receiver operating characteristic curve (ROC) analyses were used to identify alternative cut-points. Results Sixteen studies, with 76 513 participants and 8208 incident diabetes cases, were available. Compared with normoglycemia, current prediabetes definitions were associated with four to eight times higher diabetes risk (HRs (95% CIs): 3.78 (3.11 to 4.60) to 8.36 (4.88 to 14.33)) and all definitions discriminated 5-year diabetes risk with good accuracy (C-statistics 0.79-0.81). Cut-points identified through spline analysis were fasting plasma glucose (FPG) 5.1 mmol/L and glycated hemoglobin (HbA1c) 5.0% (31 mmol/mol) and cut-points identified through ROC analysis were FPG 5.6 mmol/L, 2-hour postload glucose 7.0 mmol/L and HbA1c 5.6% (38 mmol/mol). Conclusions In terms of identifying individuals at greatest risk of developing diabetes within 5 years, using prediabetes definitions that have lower values produced non-significant gain. Therefore, deciding which definition to use will ultimately depend on the goal for identifying individuals at risk of diabetes.

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  121. Television viewing time and breast cancer incidence for Japanese premenopausal and postmenopausal women: The JACC study

    Cao J., Eshak E.S., Liu K., Muraki I., Cui R., Iso H., Tamakoshi A., Mori M., Kaneko Y., Tsuji I., Nakamura Y., Iso H., Yamagishi K., Mikami H., Kurosawa M., Hoshiyama Y., Tanabe N., Tamakoshi K., Wakai K., Tokudome S., Suzuki K., Hashimoto S., Yatsuya H., Kikuchi S., Wada Y., Kawamura T., Watanabe Y., Ozasa K., Mikami K., Date C., Sakata K., Kurozawa Y., Yoshimura T., Fujino Y., Shibata A., Okamoto N., Shio H.

    Cancer Research and Treatment   51 巻 ( 4 ) 頁: 509 - 1517   2019年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Cancer Research and Treatment  

    Purpose The evidence on effects of TV viewing time among premenopausal and postmenopausal women for breast cancer risk remains controversial and limited. Materials and Methods A prospective study encompassing 33,276 (17,568 premenopausal, and 15,708 postmenopausal) women aged 40-79 years in whom TV viewing time, menstrual, and reproductive histories were determined by a self-administered questionnaire. The follow-up was from 1988 to 2009 and hazard ratios (HRs) with 95% confidence intervals (CIs) of breast cancer incidence were calculated for longer TV viewing time in reference to shorter TV viewing time by Cox proportional hazard models. Results During 16.8-year median follow-up, we found positive associations between TV viewing time and breast cancer incidence with a borderline significant trend among total women and a significant trend among postmenopausal women. Among total women, the multivariable HRs (95% CIs) for risk of breast cancer in reference to < 1.5 hr/day of TV viewing time were 0.89 (0.59-1.34) for 1.5 to < 3.0 hr/day, 1.19 (0.82-1.74) for 3.0 to < 4.5 hr/day, and 1.45 (0.91-2.32) for ≥ 4.5 hr/day (p for trend=0.053) and among postmenopausal women, the corresponding risk estimates were 1.10 (0.42-2.88), 2.54 (1.11-5.80), and 2.37 (0.92-6.10) (p for trend=0.009), respectively. Conclusion Prolonged TV viewing time was associated with increased risk of breast cancer, especially among postmenopausal women.

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  122. Smoking results in accumulation of ectopic fat in the liver. 査読有り

    Smoking results in accumulation of, ectopic fat in, the, liver, Kato A, Li Y, Ota A, Naito H, Yamada H, Nihashi T, Hotta Y, Chiang C, Hirakawa Y, Aoyama A, Tamakoshi K, Yatsuya H

    Diabetes Metab Syndr Obes   9 巻 ( 12 ) 頁: 1075 - 1080   2019年

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    記述言語:日本語  

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  123. Multicenter feasibility study of bowel preparation with castor oil for colon capsule endoscopy 査読有り 国際誌

    Ohmiya N., Hotta N., Mitsufuji S., Nakamura M., Omori T., Maeda K., Okuda K., Yatsuya H., Tajiri H.

    Gastroenterological Endoscopy   61 巻 ( 12 ) 頁: 2646 - 2655   2019年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Gastroenterological Endoscopy  

    Background and Aim: Extensive use of laxatives and incomplete excretion rates are problematic for colon capsule endoscopy (CCE). The aim of the present study was to determine the effectiveness of castor oil as a booster. Methods: At four Japanese hospitals, 319 examinees undergoing CCE were enrolled retrospectively. Before and after the introduction of castor oil, other preparation reagents were unchanged. Results: Of 319 examinees who underwent CCE, 152 and 167 examinees took regimens with castor oil (between November 2013 and June 2016) and without castor oil (between October 2015 and September 2017), respectively. Capsule excretion rates within its battery life in the groups with and without castor oil were 97% and 81%, respectively (P<0.0001). Multivariate analysis showed that ages younger than 65 years (adjusted odds ratio [OR], 3.00; P=0.0048), male gender (adjusted OR, 3.20; P=0.0051), and use of castor oil (adjusted OR, 6.29; P=0.0003) were predictors of capsule excretion within its battery life. Small bowel transit time was shorter and total volume of lavage and fluid intake was lower with castor oil than without (P = 0.0154 and 0.0013, respectively). Overall adequate cleansing level ratios with and without castor oil were 74% and 83%, respectively (P = 0.0713). Per-examinee sensitivity for polyps ≥ 6 mm with and without castor oil was 83% and 85%, respectively, with specificities of 80% and 78%, respectively. Conclusion: Bowel preparation with castor oil was effective for improving capsule excretion rate and reducing liquid loading.

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  124. Perception and practice of 'healthy' diet in relation to noncommunicable diseases among the urban and rural people in northern Ethiopia: A community-based qualitative study 査読有り 国際共著 国際誌

    Gebremariam L.W., Aoyama A., Kahsay A.B., Hirakawa Y., Chiang C., Yatsuya H., Matsuyama A.

    Nagoya Journal of Medical Science   80 巻 ( 4 ) 頁: 451 - 464   2018年11月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nagoya Journal of Medical Science  

    Dietary habits are related to the risks of noncommunicable diseases (NCDs), such as cardiovascular disease and diabetes, of which burdens are increasing in low-income countries including Ethiopia. Although several epidemiological studies of NCD risk factors were conducted in Ethiopia, qualitative studies on people's dietary habit in relation to NCDs have not been conducted yet. This study aims to describe people's perception and practice of 'healthy' diet, and barriers to practice 'healthy' diet, paying attention to the dynamics between the perception and practice. We conducted 16 key informant interviews and eight focus group discussions in an urban and a rural areas in northern Ethiopia between November 2014 and January 2016. Audio-records in local language were transcribed word-for-word, and translated into English. English text data were analyzed qualitatively, through constant comparative analysis following the principles of the grounded theory. Three themes have emerged: (1) dietary habit perceived as 'good' or 'bad' for health; (2) reasons for continuing current 'unhealthy' dietary habit; and (3) current dietary habit perceived as 'traditional.' People's practice was mostly consistent with their perception, while they sometimes practiced contrary to the perception because of personal preference and physical or financial obstacles. People were often indifferent of health implications of their habitual dietary practice, such as drinking a lot of sweet coffee. We showed dynamics between perception and practice of 'healthy' diet among people in northern Ethiopia. It is needed to increase awareness of NCDs both among the urban and rural people and to improve the social environment for removing the obstacles.

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  125. Perceptions and behavior related to noncommunicable diseases among slum dwellers in a rapidly urbanizing city, Dhaka, Bangladesh: a qualitative study 査読有り 国際共著 国際誌

    Al-Shoaibi Abubakr Ahmed Abdullah, Matsuyama Akiko, Khalequzzaman Md, Haseen Fariha, Choudhury Sohel Reza, Hoque Bilqis Amin, Chiang Chifa, Hirakawa Yoshihisa, Yatsuya Hiroshi, Aoyama Atsuko

    NAGOYA JOURNAL OF MEDICAL SCIENCE   80 巻 ( 4 ) 頁: 559-569 - 569   2018年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nagoya Journal of Medical Science  

    The increasing burden of noncommunicable diseases (NCDs) in Bangladesh can be attributable to rapid urbanization and coinciding changes in lifestyle accompanied by nutrition transition. The objective of this study is to explore respondents' lived experiences and perceptions relating to NCDs and nutrition change in an urban slum community in Dhaka. Qualitative methods were employed to explore a general understanding of behavior related to NCDs among residents of the slum community. We conducted key informant interviews of six men and seven women of various backgrounds and five focus group discussions to focus salient topics emerged from the interviews. The transcriptions of the audio-recordings were thematically analyzed, using the constant comparison method. Four major themes emerged: (1) financial hardship influencing health; (2) urbanized lifestyle affecting diet; (3) tobacco and sweetened tea as cornerstones of social life; and (4) health-seeking behavior utilizing local resources. One notable finding was that even with general economic improvement, respondents perceived poverty to be one of the major causes of NCDs. A promising finding for potentially curbing NCDs was the current trend for women to walk for exercise contrary to the commonly held notion that urban dwellers generally lead sedentary lifestyles. This study described how urban slum dwellers in Dhaka, experiencing a transition from a traditional to urbanized lifestyle, perceived their daily practices in relation to NCDs and nutrition. Our research revealed both adverse and encouraging elements of perceptions and behavior related to NCDs, which may contribute to the optimal design of NCD prevention and health promotion programs.

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  126. Clinical course of human herpesvirus 6 infection in pediatric living donor liver transplantation 査読有り 国際誌

    Yasui Toshihiro, Suzuki Tatsuya, Yoshikawa Tetsushi, Yatsuya Hiroshi, Kawamura Yoshiki, Miura Hiroki, Hara Fujio, Watanabe Shunsuke, Uga Naoko, Naoe Atsuki

    PEDIATRIC TRANSPLANTATION   22 巻 ( 7 ) 頁: e13239   2018年11月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  127. HYPERTENSION DETECTION, TREATMENT AND CONTROL RATES IN URBAN SLUM POPULATION IN BANGLADESH

    Choudhury Sohel, Al-Shoaibi Abubakr Ahmed Abdullah, Khalequzzaman Mohammad, Al Mamun Mohammad Abdullah, Chiang Chifa, Yatsuya Hiroshi, Aoyama Atsuko

    JOURNAL OF HYPERTENSION   36 巻   頁: E337-E338   2018年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  128. Dietary magnesium intake and risk of incident coronary heart disease in men: A prospective cohort study 査読有り 国際誌

    Kokubo Yoshihiro, Saito Isao, Iso Hiroyasu, Yamagishi Kazumasa, Yatsuya Hiroshi, Ishihara Junko, Maruyama Koutatsu, Inoue Manami, Sawada Norie, Tsugane Shoichiro

    CLINICAL NUTRITION   37 巻 ( 5 ) 頁: 1602 - 1608   2018年10月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Clinical Nutrition  

    Background & aims: The associations between dietary magnesium intake and stroke and coronary heart disease (CHD) incidences are inconsistent and not established in Asian. We aimed to determine the association between dietary magnesium intake and the risk of stroke and CHD in a Japanese population. Subjects/Methods: We studied 85,293 Japanese subjects by questionnaire at baseline (age 45–74 years, without cardiovascular disease or cancer in 1995 and 1998 for Cohorts I and II, respectively). The participants were followed until the end of 2009 and 2010 in Cohorts I and II, respectively. Dietary magnesium intake was estimated from a self-administered 138-item food-frequency questionnaire. Results: After 1,305,738 person-years of follow-up, 4110 strokes and 1283 cases of CHD were documented. The multivariable-adjusted hazard ratios (HRs, 95% confidence intervals, 95%CIs) of CHD for the fourth and fifth quintiles of dietary magnesium intake were 0.70 (0.50–0.99) and 0.66 (0.44–0.97) in men (P for trend = 0.036), respectively, and third quintile of dietary magnesium intake was 0.61 (0.39–0.96) in women (P for trend = 0.241), compared with the lowest quintile in men and women. We observed no decreased risks of incident stroke in men or women with higher dietary magnesium intakes. Conclusions: Higher dietary magnesium intake was associated with a reduced risk of CHD in Japanese men.

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  129. γGTPとALT追加による10年間の2型糖尿病発症リスク予測能の改善 愛知職域コホート 査読有り

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 豊嶋 英明, 青山 温子

    日本公衆衛生学会総会抄録集   77回 巻   頁: 204 - 204   2018年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  130. 食品摂取の多様性と尿中Na,K排泄量、血圧との関連 NIPPON DATA2010

    大塚 礼, 八谷 寛, 西 信雄, 奥田 奈賀子, 門田 文, 由田 克士, 大久保 孝義, 岡村 智教, 上島 弘嗣, 岡山 明, 三浦 克之

    日本公衆衛生学会総会抄録集   77回 巻   頁: 322 - 322   2018年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  131. The association between objective measures of residence and worksite neighborhood environment, and self-reported leisure-time physical activities: The Aichi Workers' Cohort Study. 査読有り 国際誌

    Li Y, Yatsuya H, Hanibuchi T, Hirakawa Y, Ota A, Uemura M, Chiang C, Otsuka R, Murata C, Tamakoshi K, Toyoshima H, Aoyama A

    Preventive medicine reports   11 巻   頁: 282 - 289   2018年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Preventive Medicine Reports  

    The possible effects of a neighborhood's built environment on physical activity have not been studied in Asian countries as much as in Western countries. The present study cross-sectionally examined the relationship between geographic information system (GIS) measured residence and worksite neighborhood walkability, and the number of parks/green spaces and sports facilities within a 1 km radius of home and workplace, with self-reported leisure-time habitual (3–4 times per week or more) walking and moderate-to-vigorous intensity habitual exercise among local government workers aged 18 to 64 years living in an urban-suburban area of Aichi, Japan in 2013. A single-level binomial regression model was used to estimate the multivariable odds ratios (ORs) and 95% confidence intervals (95% CIs). Of the 1959 male and 884 female participants, 288 (15%) and 141 (16%) reported habitual walking, respectively, and 18% and 17% reported habitual exercise, respectively. Compared with women who resided in neighborhood with a walkability index of 4–30, those living in an area with that of 35–40 were significantly more likely to engage in leisure-time habitual exercise (multivariable OR: 1.70, 95% CI: 1.08–2.68). Marginally significant positive associations were found between leisure-time habitual exercise and the residential neighborhood's number of parks/green spaces among women, as well as the number of sports facilities among men. In conclusion, a residential neighborhood environment characterized by higher walkability may contribute to the initiation or maintenance of moderate-to-vigorous intensity leisure-time exercise among working women living in an urban-suburban area of Japan.

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  132. Pooled analysis of the associations between body mass index, total cholesterol, and liver cancer-related mortality in Japan

    Ukawa S, Tamakoshi A, Murakami Y, Kiyohara Y, Yamada M, Nagai M, Satoh A, Miura K, Ueshima H, Okamura T, Imai Y, Ohkubo T, Irie F, Iso H, Kitamura A, Ninomiya T, Nakagawa H, Nakayama T, Okayama A, Sairenchi T, Saitoh S, Sakata K, Tsuji I, Kiyama M, Miyamoto Y, Ishikawa S, Yatsuya H

    Asian Pacific Journal of Cancer Prevention   19 巻 ( 8 ) 頁: 2089 - 2095   2018年8月

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    出版者・発行元:Asian Pacific Journal of Cancer Prevention  

    © 2018 Asian Pacific Organization for Cancer Prevention. Objective: We employed a large-scale pooled analysis to investigate the association of liver cancer-related mortality with being overweight/obese and total cholesterol (TC) levels, since limited and inconsistent data on these associations exist in Japan. Methods: A total of 59,332 participants (23,853 men and 35,479 women) from 12 cohorts without a history of cancer who were followed for a median of 14.3 years were analyzed. A sex-specific stratified Cox proportional hazards model adjusted for age and other potential confounders was used to calculate hazard ratios (HRs) and 95% confidence intervals (CI) for liver cancer-related mortality. Results: A total of 447 participants (266 men and 181 women) died of liver cancer within the follow-up period. Individuals classified as having a high BMI (≥25.0 kg/m2) and low TC levels (&lt; 160 mg/dL) had a significantly increased risk for liver cancer-related mortality (HR 7.05, 95% CI 4.41-11.26 in men; HR 8.07, 95% CI 4.76-13.67 in women) when compared with those in the intermediate BMI (18.5-24.9 kg/m2) and TC (160-219 mg/dL) categories. These associations remained after limiting the

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  133. Late-phase human herpesvirus 6B reactivation in hematopoietic stem cell transplant recipients 査読有り 国際誌

    Miura Hiroki, Kawamura Yoshiki, Hattori Fumihiko, Tanaka Makito, Kudo Kazuko, Ihira Masaru, Yatsuya Hiroshi, Takahashi Yoshiyuki, Kojima Seiji, Yoshikawa Tetsushi

    TRANSPLANT INFECTIOUS DISEASE   20 巻 ( 4 ) 頁: e12916   2018年8月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Transplant Infectious Disease  

    Background: We sought to determine whether late-phase human herpesvirus 6B (HHV-6B) infection in hematopoietic stem cell transplant (HSCT) recipients was associated with serious outcomes and mortality. Methods: The occurrence and course of HHV-6B infection was monitored for at least 60 days after transplant using virus isolation and real-time polymerase chain reaction. Risk factors for late-phase HHV-6B infection were examined, and the propensity score was calculated with significant risk factors. The inverse probability-weighted multivariable logistic regression analysis was performed to estimate odds ratios (ORs) and the 95% confidence intervals (95% CI) for mortality. Results: Late-phase HHV-6B infection was observed in 12/89 (13.5%) of the HSCT recipients. Older age (OR: 10.3, 95% CI: 2.1/72.9, P =.0027), hematologic malignancy (OR: 10.3, 95% CI: 1.8/97.1, P =.0063), unrelated donor transplantation (OR: 5.3, 95% CI: 1.1/36.0, P =.0345), and sex-mismatched donor transplantation (OR: 6.3, 95% CI: 1.4/39.5, P =.0149) were identified as risk factors for late-phase HHV-6B infection. Fifteen subjects died (17%). Inverse probability-weighted multivariable logistic model analysis revealed that late-phase HHV-6B infection was an independent risk factor for mortality (OR: 4.2, 95% CI: 1.7/11.0, P =.0012). Among 5 of the fatal cases of late-phase HHV-6B infection, viral infection might be associated with severe clinical manifestations. Conclusion: Late-phase HHV-6B infection in HSCT recipients was associated with worse outcomes. The full spectrum of clinical features of the infection has not been fully elucidated, and therefore, recipients with high-risk factors for late-phase HHV-6B infection should be carefully monitored.

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  134. Effect of laughter yoga on salivary cortisol and dehydroepiandrosterone among healthy university students: A randomized controlled trial 査読有り 国際誌

    Fujisawa Akiko, Ota Atsuhiko, Matsunaga Masaaki, Li Yuanying, Kakizaki Masako, Naito Hisao, Yatsuya Hiroshi

    COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE   32 巻   頁: 6 - 11   2018年8月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  135. Cardiovascular disease mortality in relation to physical activity during adolescence and adulthood in Japan: Does school-based sport club participation matter? 査読有り 国際共著 国際誌

    Gero K, Iso H, Kitamura A, Yamagishi K, Yatsuya H, Tamakoshi A

    Preventive medicine   113 巻   頁: 102 - 108   2018年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ACADEMIC PRESS INC ELSEVIER SCIENCE  

    We examined potential associations of sport club participation during adolescence and sports-related physical activity during adulthood with mortality from cardiovascular diseases (CVD) in a Japanese population. Between 1988 and 1990, 29,526 men and 41,043 women aged 40-79 years responded to a questionnaire including questions about the frequency of sports participation at baseline and sport club participation during junior/senior high school. Subjects were followed-up until the end of 2009, and 4230 cardiovascular deaths (870 CHD, 1859 stroke) were identified. Cox proportional-hazard regression models were used to estimate hazard ratios (HR). During the first-two thirds of the follow-up - where the proportional hazards assumption was met - the multivariate-adjusted HR (95% confidence interval) for total CVD mortality was 0.77 (0.61-0.98) among men and 0.82 (0.61-1.10) among women who were physically active at baseline (≥5 h/week versus 1-2 h/week). The corresponding HRs for coronary heart disease (CHD) mortality were 0.65 (0.39-1.07) and 0.40 (0.17-0.91), respectively. The combined associations of sports participation during adulthood and adolescence were also examined. Am

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  136. Non-communicable disease risk factor profile among public employees in a regional city in northern Ethiopia 査読有り 国際共著 国際誌

    Gebremariam Lemlem Weldegerima, Chiang Chifa, Yatsuya Hiroshi, Hilawe Esayas Haregot, Kahsay Alemayehu Bayray, Godefays Hagos, Abraham Loko, Hirakawa Yoshihisa, Iso Hiroyasu, Aoyama Atsuko

    SCIENTIFIC REPORTS   8 巻 ( 1 ) 頁: 9298   2018年6月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Scientific Reports  

    The burden of non-communicable diseases (NCDs) is increasing in Ethiopia. This study aims to describe the prevalence of NCD risk factors of public employees in a regional city in northern Ethiopia. We conducted a cross-sectional epidemiological study targeting men and women aged 25-64 years employed by public offices in Mekelle. The prevalence was age-standardized to the Ethiopian 2007 population. Among the 1380 subjects (823 men and 557 women), 68.7% had less than 1 serving of fruits and vegetables per day, 41.0% were physically inactive, and 57.3% observed religious fast. The age-standardised prevalence of abdominal obesity was 29.3% in men and 58.5% in women, but that of metabolic syndrome was comparable between men (39.2%) and women (39.0%). The prevalence of diabetes was underestimated if only fasting blood glucose (FBG) was used for the diagnosis compared to combination of FBG and glycated haemoglobin (HbA1c) (6.7% in men and 3.8% in women vs. 12.1% in men and 5.6% in women). More than a quarter (26.1%) of men and 8.7% of women had estimated 10-year risk of cardiovascular disease of 10% or more. This study revealed the high prevalence of NCD metabolic risk factors among the urban public employees in the highland of Ethiopia.

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  137. Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH–JAPAN study

    Hirata A, Sugiyama D, Watanabe M, Tamakoshi A, Iso H, Kotani K, Kiyama M, Yamada M, Ishikawa S, Murakami Y, Miura K, Ueshima H, Okamura T, Okamura T, Imai Y, Ohkubo T, Irie F, Iso H, Kitamura A, Ninomiya T, Kiyohara Y, Miura K, Murakami Y, Nakagawa H, Nakayama T, Okayama A, Sairenchi T, Saitoh S, Sakata K, Tamakoshi A, Tsuji I, Yamada M, Miyamoto Y, Ishikawa S, Yatsuya H

    Journal of Clinical Lipidology   12 巻 ( 3 ) 頁: 674 - 684.e5   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Clinical Lipidology  

    © 2018 National Lipid Association Background: The effect of very high or extremely high levels of high-density lipoprotein cholesterol (HDL-C) on cardiovascular disease (CVD) is not well described. Although a few recent studies have reported the adverse effects of extremely high levels of HDL-C on CVD events, these did not show a statistically significant association between extremely high levels of HDL-C and cause-specific CVD mortality. In addition, Asian populations have not been studied. Objective: We examine the impact of extremely high levels of HDL-C on cause-specific CVD mortality using pooled data of Japanese cohort studies. Methods: We performed a large-scale pooled analysis of 9 Japanese cohorts including 43,407 participants aged 40–89 years, dividing the participants into 5 groups by HDL-C levels, including extremely high levels of HDL-C ≥2.33 mmol/L (≥90 mg/dL). We estimated the adjusted hazard ratio of each HDL-C category for all-cause death and cause-specific deaths compared with HDL-C 1.04–1.55 mmol/L (40–59 mg/dL) using a cohort-stratified Cox proportional hazards model. Results: During a 12.1-year follow-up, 4995 all-cause deaths and 1280 deaths due to

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  138. 降圧剤の投与は高血圧ラット肝臓Cyp7a1プロモーターのメチル化頻度を低下させる

    内藤 久雄, 三宅 邦夫, 袁 援, 橋本 沙幸, 浅野 友美, 北森 一哉, 八谷 寛, 那須 民江

    産業衛生学雑誌   60 巻 ( 臨増 ) 頁: 303 - 303   2018年5月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  139. Association between average daily television viewing time and the incidence of ovarian cancer: findings from the Japan Collaborative Cohort Study 査読有り 国際誌

    Ukawa Shigekazu, Tamakoshi Akiko, Mori Mitsuru, Ikehara Satoyo, Shirakawa Toru, Yatsuya Hiroshi, Iso Hiroyasu

    CANCER CAUSES & CONTROL   29 巻 ( 2 ) 頁: 213 - 219   2018年2月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  140. Relationships among Socioeconomic Factors and Self-rated Health in Japanese Adults: NIPPON DATA2010 査読有り 国際誌

    Ota Atsuhiko, Yatsuya Hiroshi, Nishi Nobuo, Okuda Nagako, Ohkubo Takayoshi, Hayakawa Takehito, Kadota Aya, Okayama Akira, Miura Katsuyuki

    JOURNAL OF EPIDEMIOLOGY   28 巻 ( Supplement_III ) 頁: S66 - S72   2018年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  141. A Point System for Predicting 10-Year Risk of Developing Type 2 Diabetes Mellitus in Japanese Men: Aichi Workers' Cohort Study 査読有り

    Yatsuya Hiroshi, Li Yuanying, Hirakawa Yoshihisa, Ota Atsuhiko, Matsunaga Masaaki, Haregot Hilawe Esayas, Chiang Chifa, Zhang Yan, Tamakoshi Koji, Toyoshima Hideaki, Aoyama Atsuko

    JOURNAL OF EPIDEMIOLOGY   28 巻 ( 8 ) 頁: 347 - 352   2018年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Epidemiology  

    Background: Relatively little evidence exists for type 2 diabetes mellitus (T2DM) prediction models from long-term follow-up studies in East Asians. This study aims to develop a point-based prediction model for 10-year risk of developing T2DM in middle-aged Japanese men. Methods: We followed 3,540 male participants of Aichi Workers’ Cohort Study, who were aged 35–64 years and were free of diabetes in 2002, until March 31, 2015. Baseline age, body mass index (BMI), smoking status, alcohol consumption, regular exercise, medication for dyslipidemia, diabetes family history, and blood levels of triglycerides (TG), high density lipoprotein cholesterol (HDLC) and fasting blood glucose (FBG) were examined using Cox proportional hazard model. Variables significantly associated with T2DM in univariable models were simultaneously entered in a multivariable model for determination of the final model using backward variable selection. Performance of an existing T2DM model when applied to the current dataset was compared to that obtained in the present study’s model. Results: During the median follow-up of 12.2 years, 342 incident T2DM cases were documented. The prediction system using points assigned to age, BMI, smoking status, diabetes family history, and TG and FBG showed reasonable discrimination (c-index: 0.77) and goodness-of-fit (Hosmer-Lemeshow test, P = 0.22). The present model outperformed the previous one in the present subjects. Conclusion: The point system, once validated in the other populations, could be applied to middle-aged Japanese male workers to identify those at high risk of developing T2DM. In addition, further investigation is also required to examine whether the use of this system will reduce incidence.

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  142. [Study on the probability of incident stroke and acute myocardial infarction using DPC data]. 査読有り

    Kakizaki M, Sawada N, Yamagishi K, Yatsuya H, Saito I, Kokubo Y, Iso H, Tsugane S, Yasunaga H

    [Nihon koshu eisei zasshi] Japanese journal of public health   65 巻 ( 4 ) 頁: 179 - 186   2018年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.11236/jph.65.4_179

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  143. 肥満と動脈硬化

    八谷 寛, 李 媛英, 金子 佳世, 太田 充彦

    食と医療   4 巻   頁: 72 - 79   2018年

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  144. Prevalence of non-communicable disease risk factors among poor shantytown residents in Dhaka, Bangladesh: a community-based cross-sectional survey 査読有り 国際共著 国際誌

    Khalequzzaman Md, Chiang Chifa, Choudhury Sohel Reza, Yatsuya Hiroshi, Al-Mamun Mohammad Abdullah, Al-Shoaibi Abubakr Ahmed Abdullah, Hirakawa Yoshihisa, Hoque Bilqis Amin, Islam Syed Shariful, Matsuyama Akiko, Iso Hiroyasu, Aoyama Atsuko

    BMJ OPEN   7 巻 ( 11 ) 頁: e014710   2017年11月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:BMJ Open  

    Objectives This study aims to describe the prevalence of non-communicable disease (NCD) risk factors among the urban poor in Bangladesh. Design We conducted a community-based cross-sectional epidemiological study. Setting The study was conducted in a shantytown in the city of Dhaka. There were 8604 households with 34 170 residents in the community. Those households were categorised into two wealth strata based on the housing structure. Participants The study targeted residents aged 18-64 years. A total of 2986 eligible households with one eligible individual were selected by simple random sampling stratified by household wealth status. A total of 2551 residents completed the questionnaire survey, and 2009 participated in the subsequent physical and biochemical measurements. Outcome measures A modified WHO survey instrument was used for assessing behavioural risk factors and physical and biochemical measurements, including glycated haemoglobin (HbA1c). The prevalence of NCD risk factors, such as tobacco use, fruit and vegetable intake, overweight/obesity, hypertension, diabetes (HbA1c ≥6.5%) and dyslipidaemia, was described according to household wealth status and gender differences. Results The prevalence of current tobacco use was 60.4% in men and 23.5% in women. Most of them (90.8%) consumed more than 1 serving of fruits and vegetables per day; however, only 2.1% consumed more than 5 servings. Overweight/obesity was more common in women (39.2%) than in men (18.9%), while underweight was more common in men (21.0%) than in women (7.1%). The prevalence of hypertension was 18.6% in men and 20.7% in women. The prevalence of diabetes was 15.6% in men and 22.5% in women, which was much higher than the estimated national prevalence (7%). The prevalence of raised total cholesterol (≥190 mg/dL) was 25.7% in men and 34.0% in women. Conclusion The study identified that tobacco use, both overweight and underweight, diabetes, hypertension and dyslipidaemia were prevalent among the urban poor in Bangladesh.

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  145. Alcohol consumption and mortality from aortic disease among Japanese men: The Japan Collaborative Cohort study 査読有り 国際誌

    Shirakawa Toru, Yamagishi Kazumasa, Yatsuya Hiroshi, Tanabe Naohito, Tamakoshi Akiko, Iso Hiroyasu

    ATHEROSCLEROSIS   266 巻   頁: 64 - 68   2017年11月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Atherosclerosis  

    Background and aims Only a few population-based prospective studies have examined the association between alcohol consumption and abdominal aortic aneurysm, and the results are inconsistent. Moreover, no evidence exists for aortic dissection. We examined the effect of alcohol consumption on risk of mortality from aortic diseases. Methods A total of 34,720 men from the Japan Collaborative Cohort study, aged 40–79 years, without history of cardiovascular disease and cancer at baseline 1988 and 1990 were followed up until the end of 2009 for their mortality and its underlying cause. Hazard ratios of mortality from aortic diseases were estimated according to alcohol consumption categories of never-drinkers, ex-drinkers, regular drinkers of ≤30 g, and >30 g ethanol per day. Results During the median 17.9-year follow-up period, 45 men died of aortic dissection and 41 men died of abdominal aortic aneurysm. Light to moderate drinkers of ≤30 g ethanol per day had lower risk of mortality from total aortic disease and aortic dissection compared to never-drinkers. The respective multivariable hazard ratios (95% confidence intervals) were 0.46 (0.28–0.76) for total aortic disease and 0.16 (0.05–0.50) for aortic dissection. Heavy drinkers of >30 g ethanol per day did not have reduced risk of mortality from total aortic disease, albeit had risk variation between aortic dissection and abdominal aortic aneurysm. Conclusions Light to moderate alcohol consumption was associated with reduced mortality from aortic disease among Japanese men.

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  146. Association of high-density lipoprotein cholesterol concentration with different types of stroke and coronary heart disease: The Japan Public Health Center-based prospective (JPHC) study 査読有り 国際誌

    Saito Isao, Yamagishi Kazumasa, Kokubo Yoshihiro, Yatsuya Hiroshi, Iso Hiroyasu, Sawada Norie, Inoue Manami, Tsugane Shoichiro

    ATHEROSCLEROSIS   265 巻   頁: 147 - 154   2017年10月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  147. Functional capacity, self-rated health status, and psychosocial characteristics of employed cancer survivors in Japan 査読有り 国際誌

    Katoh Y, Ota A, Yatsuya H, Li Y, Naito H, Fujisawa A, Matsunaga M, Hirakawa Y, Chiang C, Toyoshima H, Tamakoshi K, Aoyama A

    Fujita Medical Journal   3 巻 ( 3 ) 頁: 55 - 61   2017年8月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:藤田学園医学会  

    <p><b>Objectives:</b> This study investigated restrictions in functional capacity, self-rated health status (SRHS), and psychosocial characteristics of employed cancer survivors in Japan and examined differences in these characteristics between cancer survivors and employees without cancer history.</p><p><b>Methods:</b> A cross-sectional survey was carried out. Subjects were local government employees in Japan in 2013 (n=5,474). Using a self-administered questionnaire, we evaluated restrictions in functional capacity, SRHS, and the following psychosocial characteristics: social support, perceived stress, social capital, positive reasons for living (ikigai), and happiness. We examined whether cancer history was associated with restrictions in functional capacity, SRHS, and psychosocial characteristics.</p><p><b>Results:</b> A total of 112 employees were cancer survivors. Of these, males of all ages and comparatively younger females had restrictions in functional capacity more frequently than the corresponding subjects without cancer history (males of all ages: 14.5% vs. 2.9%, p<0.001; females <50 years: 15.2% vs. 1.1%, p<0.001). Among males of all ages, cancer survivors reported bad SRHS more frequently than employees without cancer history (8.1% vs. 1.5%, p=0.003). No significant differences were found in psychosocial characteristics by cancer history.</p><p><b>Conclusions:</b> Male and comparatively young female employed cancer survivors frequently experienced restrictions in functional capacity. Male employed cancer survivors self-rated their health status as bad more frequently than male employees without cancer history.</p>

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  148. A pooled analysis of the association of isolated low levels of high-density lipoprotein cholesterol with cardiovascular mortality in Japan 査読有り

    Takumi Hirata, Daisuke Sugiyama, Shin-ya Nagasawa, Yoshitaka Murakami, Shigeyuki Saitoh, Akira Okayama, Hiroyasu Iso, Fujiko Irie, Toshimi Sairenchi, Yoshihiro Miyamoto, Michiko Yamada, Shizukiyo Ishikawa, Katsuyuki Miura, Hirotsugu Ueshima, Tomonori Okamura, for the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group, Hirotsugu Ueshima, Tomonori Okamura, Yutaka Imai, Takayoshi Ohkubo, Fujiko Irie, Hiroyasu Iso, Akihiko Kitamura, Yutaka Kiyohara, Katsuyuki Miura, Yoshitaka Murakami, Hideaki Nakagawa, Takeo Nakayama, Akira Okayama, Toshimi Sairenchi, Shigeyuki Saitoh, Kiyomi Sakata, Akiko Tamakoshi, Ichiro Tsuji, Michiko Yamada, Masahiko Kiyama, Yoshihiro Miyamoto, Shizukiyo Ishikawa, Hiroshi Yatsuya, Tomonori Okamura

    European Journal of Epidemiology   32 巻 ( 7 ) 頁: 547 - 557   2017年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Netherlands  

    Low levels of serum high-density lipoprotein cholesterol (HDL-C) have been shown to be associated with increased risk of coronary heart disease (CHD). However, because this is usually observed in the context of other lipid abnormalities, it is not known whether isolated low serum HDL-C levels are an independent risk factor for CHD. We performed a large pooled analysis in Japan using data from nine cohorts with 41,206 participants aged 40–89 years who were free of cardiovascular disease at baseline. We divided participants into three groups: isolated low HDL-C, non-isolated low HDL-C, and normal HDL-C. Cohort-stratified Cox proportional hazards models were used to estimate multivariate-adjusted hazard ratios (HRs) for death due to CHD, ischemic stroke, and intracranial cerebral hemorrhage
    during a 12.9-year follow-up, we observed 355, 286, and 138 deaths, respectively, in these groups. Non-isolated low HDL-C was significantly associated with increased risk of CHD compared with normal HDL-C (HR 1.37, 95 % confidence interval (CI) 1.04–1.80)
    however, isolated low HDL-C was not. Although isolated low HDL-C was significantly associated with decreased risk of CHD (HR 0.51, 95 % CI 0.29–0.89) in women, it was significantly associated with increased risk of intracranial cerebral hemorrhage in all participants (HR 1.62, 95 % CI 1.04–2.53) and in men (HR 2.00, 95 % CI 1.04–3.83). In conclusion, isolated low HDL-C levels are not associated with increased risk of CHD in Japan. CHD risk may, therefore, be more strongly affected by serum total cholesterol levels in this population.

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  149. Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study 査読有り 国際共著 国際誌

    Lubin Jay H., Couper David, Lutsey Pamela L., Yatsuya Hiroshi

    NICOTINE & TOBACCO RESEARCH   19 巻 ( 7 ) 頁: 826 - 835   2017年7月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  150. Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan Collaborative Cohort Study 査読有り 国際誌

    Matsunaga Masaaki, Yatsuya Hiroshi, Iso Hiroyasu, Yamashita Kentaro, Li Yuanying, Yamagishi Kazumasa, Tanabe Naohito, Wada Yasuhiko, Wang Chaochen, Ota Atsuhiko, Tamakoshi Koji, Tamakoshi Akiko

    ATHEROSCLEROSIS   261 巻   頁: 124 - 130   2017年6月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Atherosclerosis  

    Background and aims Coronary heart disease (CHD) and stroke have common risk factors, but some of these differ in the magnitude or direction of associations between CHD and stroke. We assessed whether the impact of each risk factor differed between CHD and stroke mortality in Asians. Methods In total, 104 910 subjects aged 40–79 years without histories of cancer, CHD and stroke at baseline were followed between 1988 and 2009. Competing-risks analysis was used to test for differences in the associations of each risk factor with two endpoints (CHD and stroke). Population attributable fractions (PAFs) were also calculated for these endpoints to estimate the population impact of each risk factor. Results During a median 19.1-year follow-up, 1554 died from CHD and 3163 from stroke. The association of hypertension with CHD was similar to that with stroke in terms of the magnitude and direction (multivariable-adjusted hazard ratio for CHD: 1.63 vs. stroke: 1.73 in men and 1.70 vs. 1.66 in women). Conversely, the magnitude of these associations differed for smoking (CHD: 1.95 vs. stroke: 1.23 in men and 2.45 vs. 1.35 in women) and diabetes (1.49 vs. 1.09 in men and 2.08 vs. 1.39 in women). The highest PAF for CHD was caused by smoking in men and by hypertension in women; that for stroke was caused by hypertension in both sexes. Conclusions Hypertension associations and PAFs were consistent between CHD and stroke, but not for other risk factors. These findings may be useful to optimize public health intervention strategies.

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  151. Disparity in metabolic risk factors of non-communicable diseases between Palauans and Filipinos living in Palau. 査読有り 国際誌

    Osako A, Chiang C, Ito K, Yatsuya H, Haregot Hilawe E, Ikerdeu E, Honjo K, Mita T, Cui R, Hirakawa Y, Madraisau S, Ngirmang G, Iso H, Aoyama A

    Nagoya journal of medical science   79 巻 ( 2 ) 頁: 157 - 165   2017年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nagoya Journal of Medical Science  

    Non-communicable diseases have been recognized as a serious threat to public health in Palau. To tackle the problem, different strategies might be necessary for populations with different ethnic backgrounds. This study aims to find the differences in the prevalence of metabolic risk factors of non-communicable diseases between Palauans and Filipinos living in Palau, and examine possible determinants of the differences. We selected data of 2,032 participants, including native Palauans and Filipinos, from the Palau STEPS Survey 2011-2013 for this study. Logistic regression models were used to inspect the association of each metabolic risk factor with ethnicity by calculating odds ratios adjusted for potential confounding factors. Palauans had higher age-standardized prevalence of overweight or obesity (84% vs. 45%), hypertension (50% vs. 38%) and diabetes (19% vs. 13%) than Filipinos. However, after adjusting for BMI and various lifestyle related factors, there are no statistical significant differences in the prevalence of hypertension and diabetes between these two ethnic groups. Palauan men were less likely to have elevated total cholesterol, especially after adjusting for BMI (odds ratio=0.55, 95% confidence interval: 0.33-0.91), while Palauan women were more likely to have elevated triglycerides than their Filipino counterparts (odds ratio=1.45, 95% confidence interval: 1.02-2.06). Our findings suggested that Palauans' higher BMI distribution might be able to explain their higher prevalence of hypertension and partially explain their higher diabetes prevalence. Palauans were not consistently more likely to have all metabolic risk factors, namely dyslipidemia were less likely to be observed in Palauan men.

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  152. Passive smoking and chronic obstructive pulmonary disease mortality: findings from the Japan collaborative cohort study 査読有り 国際誌

    Ukawa Shigekazu, Tamakoshi Akiko, Yatsuya Hiroshi, Yamagishi Kazumasa, Ando Masahiko, Iso Hiroyasu

    INTERNATIONAL JOURNAL OF PUBLIC HEALTH   62 巻 ( 4 ) 頁: 489 - 494   2017年5月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:International Journal of Public Health  

    Objectives: To elucidate the association between passive smoking at home and chronic obstructive pulmonary disease (COPD) mortality via a large-scale nationwide cohort study in Japan. Methods: Never smokers (n = 34,604) aged 40–79 years at baseline (1988–1990; 4884 men, 29,720 women) were included in the analysis. Passive smoking at home was measured based on self-reported frequency of weekly exposure to passive smoking at home. An inverse probability of treatment-weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for COPD mortality. Results: During a median follow-up of 16.4 years, 33 participants (10 men, 23 women) died of COPD. The HR for participants exposed to passive smoking at home ≤4 days per week or those who had almost daily exposure to passive smoking at home had a significantly increased risk of COPD mortality (HR 2.40, 95% CI 1.39–4.15, HR 2.88, 95% CI 1.68–4.93, respectively). Conclusions: The present findings suggest that avoiding passive smoking at home may be beneficial for preventing death due to COPD among never smokers.

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  153. Descriptive Epidemiology of Hypertension and Its Association With Obesity: Based on the WHO STEPwise Approach to Surveillance in Palau 査読有り 国際共著 国際誌

    Wang Chaochen, Chiang Chifa, Yatsuya Hiroshi, Hilawe Esayas Haregot, Ikerdeu Edolem, Honjo Kaori, Mita Takashi, Cui Renzhe, Hirakawa Yoshihisa, Madraisau Sherilynn, Iso Hiroyasu, Aoyama Atsuko

    ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH   29 巻 ( 4 ) 頁: 278 - 287   2017年5月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Asia-Pacific Journal of Public Health  

    The rise of noncommunicable diseases is a serious health burden for Palau. This study described the prevalence of hypertension, and assessed its association with obesity. Surveys following the WHO STEPwise approach to surveillance were conducted in 2529 adults. Multivariate prevalence ratios (PR) of hypertension for body mass index (BMI) categories were calculated by logistic regression models using conditional standardization procedure. Age- and sex-specified analyses were performed. Overall prevalence of obesity and hypertension were 40.4% and 46.8%, respectively. Prevalence of hypertension was positively associated with BMI. However, overweight men had as high prevalence of hypertension as the obese (multivariable-adjusted PR was 1.84 for overweight and 1.91 for obese compared with nonoverweight). The association between hypertension and BMI was similar across age groups. The prevalence of hypertension in women increased gradually with the increase of BMI whereas that in men reached a plateau already in the overweight.

    DOI: 10.1177/1010539517704042

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  154. Increased airway hyperresponsiveness to adenosine in patients with aspirin intolerant asthma 査読有り 国際誌

    Isogai Sumito, Niwa Yoshikazu, Yatsuya Hiroshi, Hayashi Masamichi, Yamamoto Naoki, Okamura Takuya, Minezawa Tomoyuki, Goto Yasuhiro, Yamaguchi Teppei, Takeyama Tomoko, Sakakibara Yosuke, Morikawa Sayako, Horiguchi Tomoya, Gotoh Yusuke, Mieno Yuki, Uozu Sakurako, Nakanishi Toru, Okazawa Mitsushi, Sakakibara Hiroki, Imaizumi Kazuyoshi

    ALLERGOLOGY INTERNATIONAL   66 巻 ( 2 ) 頁: 360 - 362   2017年4月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.alit.2016.10.001

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  155. Long-term weight-change slope, weight fluctuation and risk of type 2 diabetes mellitus in middle-aged Japanese men and women: findings of Aichi Workers' Cohort Study 査読有り 国際誌

    Zhang Y., Yatsuya H., Li Y., Chiang C., Hirakawa Y., Kawazoe N., Tamakoshi K., Toyoshima H., Aoyama A.

    NUTRITION & DIABETES   7 巻 ( 3 )   2017年3月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Nutrition and Diabetes  

    OBJECTIVE: This study aims to investigate the association of long-term weight-change slopes, weight fluctuation and the risk of type 2 diabetes mellitus (T2DM) in middle-aged Japanese men and women. METHODS: A total of 4234 participants of Aichi Workers' Cohort Study who were aged 35-66 years and free of diabetes in 2002 were followed through 2014. Past body weights at the ages of 20, 25, 30, 40 years, and 5 years before baseline as well as measured body weight at baseline were regressed on the ages. Slope and root-mean-square-error of the regression line were obtained and used to represent the weight changes and the weight fluctuation, respectively. The associations of the weight-change slopes and the weight fluctuation with incident T2DM were estimated by Cox proportional hazards models. RESULTS: During the median follow-up of 12.2 years, 400 incident cases of T2DM were documented. After adjustment for baseline overweight and other lifestyle covariates, the weight-change slopes were significantly associated with higher incidence of T2DM (hazard ratio (HR): 1.80, 95% confident interval (CI): 1.17-2.77 for men; and HR: 2.78, 95% CI: 1.07-7.23 for women), while the weight fluctuation was not (HR: 1.08, 95% CI: 1.00-1.18 for men and HR: 1.02, 95% CI: 0.84-1.25 for women). CONCLUSIONS: Regardless of the presence of overweight, the long-term weight-change slopes were significantly associated with the increased risk of T2DM; however, the weight fluctuation was not associated with the risk of T2DM in middle-aged Japanese men and women.

    DOI: 10.1038/nutd.2017.5

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  156. Daily Walking Time and Pneumonia Mortality Among Elderly With/Without Medical History of Myocardial Infarction or Stroke

    Ukawa Shigekazu, Zhao Wenjing, Yatsuya Hiroshi, Yamagishi Kazumasa, Iso Hiroyasu, Tamakoshi Akiko

    CIRCULATION   135 巻   2017年3月

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    記述言語:日本語  

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  157. Daily Walking Time and Pneumonia Mortality Among Elderly With/Without Medical History of Myocardial Infarction or Stroke 査読有り

    Shigekazu Ukawa, Wenjing Zhao, Hiroshi Yatsuya, Kazumasa Yamagishi, Hiroyasu Iso, Akiko Tamakoshi

    CIRCULATION   135 巻   2017年3月

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    記述言語:英語   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

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  158. No modifying effect of education level on the association between lifestyle behaviors and cardiovascular mortality: the Japan Collaborative Cohort Study 査読有り 国際誌

    Eguchi Eri, Iso Hiroyasu, Honjo Kaori, Yatsuya Hiroshi, Tamakoshi Akiko

    SCIENTIFIC REPORTS   7 巻   頁: 39820   2017年1月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1038/srep39820

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  159. Population profile and residential environment of an urban poor community in Dhaka, Bangladesh 査読有り 国際共著 国際誌

    Khalequzzaman Md, Chiang Chifa, Hoque Bilqis Amin, Choudhury Sohel Reza, Nizam Saika, Yatsuya Hiroshi, Matsuyama Akiko, Hirakawa Yoshihisa, Islam Syed Shariful, Iso Hiroyasu, Aoyama Atsuko

    ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE   22 巻 ( 1 ) 頁: 1   2017年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Environmental Health and Preventive Medicine  

    Objectives: A population survey was conducted in an urban shantytown in Bangladesh, as a baseline study of future epidemiological studies. This paper aims to describe the findings of the study, including the population profile and residential environment of the urban poor. Methods: We conducted a complete count household survey in an urban poor community in Dhaka. Using a brief structured questionnaire in Bengali language, trained interviewers visited each household and asked questions such as: duration of residence; ownership of house, toilet and kitchen; water supply; number of family members; age, sex, education, occupation, tobacco use, and history of diseases of each family member. Results: We found that there were 8604 households and 34,170 people in the community. Average number of household members was 4.0. Most people had access to safe water, but only 16% lived in the house with a toilet. Based on the proxy indicators of household wealth levels, we identified that about 39% were relatively well-off, while the rest were very poor. Tobacco use was prevalent in men regardless of age and in women aged over 35 years. Prevalence of self-reported hypertension and diabetes was slightly higher in women than in men, although over 70% of the respondents didn't know if they had such diseases. Incidences of diarrhea in the last one month were relatively low. Conclusions: The study showed population profile and sanitation environment in an urban poor community by a complete count survey. We expect the study to serve as a baseline for future epidemiological studies.

    DOI: 10.1186/s12199-017-0610-2

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  160. Risk Factor of Cardiovascular Disease Among Older Individuals 査読有り 国際誌

    Yatsuya Hiroshi, Matsunaga Masaaki, Li Yuanying, Ota Atsuhiko

    JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS   24 巻 ( 3 ) 頁: 258 - 261   2017年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.5551/jat.Ed064

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  161. Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN) 査読有り

    Yoichiro Hirakawa, the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Toshiharu Ninomiya, Yutaka Kiyohara, Yoshitaka Murakami, Shigeyuki Saitoh, Hideaki Nakagawa, Akira Okayama, Akiko Tamakoshi, Kiyomi Sakata, Katsuyuki Miura, Hirotsugu Ueshima, Tomonori Okamura, Yutaka Imai, Takayoshi Ohkubo, Fujiko Irie, Hiroyasu Iso, Akihiko Kitamura, Takeo Nakayama, Toshimi Sairenchi, Ichiro Tsuji, Michiko Yamada, Masahiko Kiyama, Yoshihiro Miyamoto, Shizukiyo Ishikawa, Hiroshi Yatsuya

    Journal of Epidemiology   27 巻 ( 3 ) 頁: 123 - 129   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Japan Epidemiology Association  

    Background: Diabetes mellitus is a strong risk factor for cardiovascular disease. However, the age-specific association of diabetes with cardiovascular risk, especially in the elderly, remains unclear in non-Western populations. Methods: A pooled analysis was conducted using 8 cohort studies (mean follow-up period, 10.3 years) in Japan, combining the data from 38,854 individual participants without history of cardiovascular disease. In all, 1867 of the participants had diabetes, defined based on the 1998 World Health Organization criteria. The association between diabetes and the risk of death from cardiovascular disease, coronary heart disease (CHD), and stroke was estimated using a stratified Cox model, accounting for variability of baseline hazard functions among cohorts. Results: During the follow-up, 1376 subjects died of cardiovascular disease (including 268 of coronary heart disease and 621 of stroke). Diabetes was associated with an increased risk of cardiovascular death after multivariable adjustment (hazard ratio [HR] 1.62
    95% confidence interval [CI], 1.35-1.94). Similarly, diabetes was a risk factor for CHD (HR 2.13
    95% CI, 1.47-3.09) and stroke (HR 1.40
    95% CI, 1.05-1.85). In the age-stratified analysis of the risk of cardiovascular death, the relative effects of diabetes were consistent across age groups (p for heterogeneity = 0.18), whereas the excess absolute risks of diabetes were greater in participants in their 70s and 80s than in younger subjects. Conclusions: The management of diabetes is important to reduce the risk of death from cardiovascular disease, not only in midlife but also in late life, in the Japanese population.

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  162. Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study 査読有り

    Yamagishi K, Iso H, Yatsuya H, Tanabe N, Date C, Kikuchi S, Yamamoto A, Inaba Y, Tamakoshi A; JACC Study Group.

    Am J Clin Nutr   92 巻 ( 4 ) 頁: 759-765   2010年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  163. Sex-Specific HDL Cholesterol Changes With Weight Loss and Their Association With Anthropometric Variables: The LIFE Study 査読有り

    Yatsuya H, Jeffery RW, Erickson DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Mitchell NR, Langer SL, Levy RL

    Obesity (Silver Spring)   Epub 巻   2010年9月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  164. Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study.

    Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR; ARIC Study Investigators.

    J Epidemiol   20 巻 ( 5 ) 頁: 347-354   2010年9月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  165. Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study. 査読有り

    Yatsuya H, Folsom AR; ARIC Investigators.

    Am J Epidemiol   172 巻 ( 5 ) 頁: 600-605   2010年9月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  166. Body mass index and risk of stroke and myocardial infarction in a relatively lean population: meta-analysis of 16 Japanese cohorts using individual data. 査読有り

    Yatsuya H, Toyoshima H, Yamagishi K, Tamakoshi K, Taguri M, Harada A, Ohashi Y, Kita Y, Naito Y, Yamada M, Tanabe N, Iso H, Ueshima H; Japan Arteriosclerosis Longitudinal Study (JALS) group.

    Circ Cardiovasc Qual Outcomes.   3 巻 ( 5 ) 頁: 498-505   2010年9月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  167. Maintenance-tailored therapy vs. standard behavior therapy for 30-month maintenance of weight loss. 査読有り

    Levy RL, Jeffery RW, Langer SL, Graham DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Finch EA, Hotop AM, Yatsuya H.

    Prev Med   Epub 巻   2010年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  168. Incidence of metabolic syndrome according to combinations of lifestyle factors among middle-aged Japanese male workers. 査読有り

    Li Y, Yatsuya H, Iso H, Tamakoshi K, Toyoshima H.

    Prev Med   51 巻 ( 2 ) 頁: 118-122   2010年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  169. Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities Study 査読有り

    Yatsuya H, Folsom AR, Wong TY, Klein R, Klein BE, Sharrett AR; ARIC Study Investigators.

    Stroke   41 巻 ( 7 ) 頁: 1349-1355   2010年7月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  170. Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study). 査読有り

    Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR.

    Am J Cardiol   105 巻 ( 10 ) 頁: 1420-1425   2010年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  171. Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese. 査読有り

    Muramatsu T, Yatsuya H, Toyoshima H, Sasaki S, Li Y, Otsuka R, Wada K, Hotta Y, Mitsuhashi H, Matsushita K, Murohara T, Tamakoshi K.

    Prev Med.   50 巻 ( 5-6 ) 頁: 272-276   2010年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  172. Race- and Sex-Specific Associations of Obesity Measures With Ischemic Stroke Incidence in the Atherosclerosis Risk in Communities (ARIC) Study 査読有り

    Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J; for the ARIC Study Investigators

    Stroke   41 巻 ( 3 ) 頁: 417-425   2010年3月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND AND PURPOSE: Studies have suggested differences in the association between obesity and ischemic stroke in black versus white populations. In this study, we explored ischemic stroke risk in relation to a variety of obesity measures by sex and race. METHODS: Using data from the Atherosclerosis Risk in Communities Study, we obtained information on body mass index, waist circumference, and waist-to-hip ratio from 13 549 black and white participants who were aged 45 to 65 years between 1987 and 1989. All were free of cardiovascular disease and cancer at baseline. Incident strokes over a median follow-up of 16.9 years were ascertained from hospital records. RESULTS: Although crude incidence rates of ischemic stroke varied more than 3-fold by race and sex, the relationship between higher measures of obesity and ischemic stroke risk was positive and linear across all groups. The crude incidence of ischemic stroke was 1.2 per 1000 person-years for white women with the lowest body mass index, ranging up to 8.0 per 1000 person-years for black men with the highest body mass index. Hazard ratios for the highest versus lowest quintile of body mass index, waist circumference, and waist-to-hip ratio ranged from 1.43 to 3.19, indicating increased stroke risk associated with obesity, however it was measured, even after adjustment for potential confounders. Additional adjustment for factors that may mediate the relationship, such as diabetes and hypertension, significantly attenuated the associations, suggesting that these factors may explain much of the stroke risk associated with obesity. CONCLUSIONS: Degree of obesity, defined by body mass index, waist circumference, or waist-to-hip ratio, was a significant risk factor for ischemic stroke regardless of sex or race.

  173. Daytime napping and mortality, with a special reference to cardiovascular disease: the JACC study 査読有り

    Tanabe N, Iso H, Seki N, Suzuki H, Yatsuya H, Toyoshima H, Tamakoshi A; for the JACC Study Group

    Int J Epidemiol   39 巻 ( 1 ) 頁: 233-243   2010年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  174. BMI and all-cause mortality among Japanese older adults: findings from the Japan collaborative cohort study. 査読有り

    Tamakoshi A, Yatsuya H, Lin Y, Tamakoshi K, Kondo T, Suzuki S, Yagyu K, Kikuchi S; JACC Study Group

    Obesity (Silver Spring)   18 巻 ( 2 ) 頁: 362-369   2010年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  175. Vaginal douching in Cambodian women: its prevalence and association with vaginal candidiasis 査読有り

    Heng LS, Yatsuya H, Morita S, Sakamoto J

    J Epidemiol   20 巻 ( 1 ) 頁: 70-76   2010年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  176. Changes in C-reactive protein during weight loss and the association with changes in anthropometric variables in men and women: LIFE Study. 査読有り

    Yatsuya H, Jeffery RW, Langer SL, Mitchell N, Flood AP, Welsh EM, Jaeb MA, Laqua PS, Crowell M, Levy RL

    Int J Obes (Lond).   Epub 巻   2010年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

  177. Factors predicting growth of vestibular schwannoma in neurofibromatosis type 2. 査読有り

    Ito E, Saito K, Yatsuya H, Nagatani T, Otsuka G

    Neurosurg Rev   32 巻 ( 4 ) 頁: 425-433   2009年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  178. Changes in activities of dail living, physical fitness, and depressive symptoms after six-month periodic well-rounded exercise programs for older adults living in nursing homes or special nursing facilities 査読有り

    Ouyang P, Yatsuya H, Toyoshima H, Otsuka R, Wada K, Matsushita K, Ishikawa M, Lee Y, Hotta Y, Mitsuhashi H, Muramatsu T, Kasuga N, Tamakoshi K

    Nagoya J Med Sci   71 巻 ( 3-4 ) 頁: 115-126   2009年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  179. Multilevel analyses of effects of variation in body mass index on serum lipid concentrations in middle-aged Japanese men. 査読有り

    Kondo T, Kimata A, Yamamoto K, Ueyama S, Ueyama J, Yatsuya H, Tamakoshi K, Hori Y

    Nagoya J Med Sci   71 巻 ( 1-2 ) 頁: 19-28   2009年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  180. Upper airway morphology in patients with obstructive sleep apnea syndrome: Effects of lateral positioning. 査読有り

    Soga T, Nakata S, Yasuma F, Noda A, Sugiura T, Yatsuya H, Koike Y, Ozaki N, Nakashima T.

    Auris Nasus Larynx   36 巻 ( 3 ) 頁: 305-309   2009年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  181. An influence of Interferon-gamma gene polymorphisms on treatment response to tuberculosis in Japanese population. 査読有り

    Shibasaki M, Yagi T, Yatsuya H, Okamoto M, Nishikawa M, Baba H, Hashimoto N, Senda K, Kawabe T, Nakashima K, Imaizumi K, Shimokata K, Hasegawa Y

    J Infect   58 巻 ( 6 ) 頁: 467-469   2009年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  182. Uric Acid and left ventricular hypertrophy in Japanese men. 査読有り

    Mitsuhashi H, Yatsuya H, Matsushita K, Zhang H, Otsuka R, Muramatsu T, Takefuji S, Hotta Y, Kondo T, Murohara T, Toyoshima H, Tamakoshi K.

    Circ J   73 巻 ( 4 ) 頁: 667-672   2009年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  183. Group education with personal rehabilitation for idiopathic Parkinson's disease. 査読有り

    Guo L, Jiang Y, Yatsuya H, Yoshida Y, Sakamoto J.

    Can J Neurol Sci   36 巻 ( 1 ) 頁: 51-59   2009年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  184. Effect of the interaction between mental stress and eating pattern on body mass index gain in healthy Japanese male workers. 査読有り

    Toyoshima H, Masuoka N, Hashimoto S, Otsuka R, Sasaki S, Tamakoshi K, Yatsuya H.

    J Epidemiol   19 巻 ( 2 ) 頁: 88-93   2009年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  185. Contribution of adipocytokines to low-grade inflammatory state as expressed by circulating C-reactive protein in Japanese men: comparison of leptin and adiponectin. 査読有り

    Sugiura K, Tamakoshi K, Yatsuya H, Otsuka R, Wada K, Matsushita K, Kondo T, Hotta Y, Mitsuhashi H, Murohara T, Toyoshima H.

    Int J Cardiol   130 巻 ( 2 ) 頁: 159-164   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  186. Effect of physical activity on breast cancer risk: findings of the Japan collaborative cohort study. 査読有り

    Suzuki S, Kojima M, Tokudome S, Mori M, Sakauchi F, Fujino Y, Wakai K, Lin Y, Kikuchi S, Tamakoshi K, Yatsuya H, Tamakoshi A; Japan Collaborative Cohort Study Group.

    Cancer Epidemiol Biomarkers Prev   17 巻 ( 12 ) 頁: 3396-3401   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  187. Development and validity of the Japanese version of body shape silhouette: relationship between self-rating silhouette and measured body mass index. 査読有り

    Nagasaka K, Tamakoshi K, Matsushita K, Toyoshima H, Yatsuya H.

    Nagoya J Med Sci   70 巻 ( 3-4 ) 頁: 89-96   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  188. Self-reported medical history was generally accurate among Japanese workplace population. 査読有り

    Wada K, Yatsuya H, Ouyang P, Otsuka R, Mitsuhashi H, Takefuji S, Matsushita K, Sugiura K, Hotta Y, Toyoshima H, Tamakoshi K.

    J Clin Epidemiol   62 巻 ( 3 ) 頁: 306-313   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  189. Having more healthy practice was associated with low white blood cell counts in middle-aged Japanese male and female workers. 査読有り

    Otsuka R, Tamakoshi K, Wada K, Matsushita K, Ouyang P, Hotta Y, Takefuji S, Mitsuhashi H, Toyoshima H, Shimokata H, Yatsuya H.

    Ind Health   46 巻 ( 4 ) 頁: 341-347   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  190. TH1/TH2 immune response in lung fibroblasts in interstitial lung disease. 査読有り

    Sumida A, Hasegawa Y, Okamoto M, Hashimoto N, Imaizumi K, Yatsuya H, Yokoi T, Takagi K, Shimokata K, Kawabe T.

    Arch Med Res   39 巻 ( 5 ) 頁: 503-510   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  191. Further inflammatory information on metabolic syndrome by adiponectin evaluation. 査読有り

    Int J Cardiol   124 巻 ( 3 ) 頁: 339-344   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  192. Low leptin but high insulin resistance of smokers in Japanese men. 査読有り

    Hotta Y, Yatsuya H, Toyoshima H, Matsushita K, Mitsuhashi H, Takefuji S, Oiso Y, Tamakoshi K.

    Diabetes Res Clin Pract   81 巻 ( 3 ) 頁: 358-364   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    We investigated the association between smoking and leptin, and to discuss their influence on diabetes in a large-scale study of Japanese men. METHODS: A cross-sectional study was carried out in 2002. The subjects were 2836 men aged 35-66. Smoking history was investigated in a self-administered questionnaire. Blood leptin, glucose and insulin were measured. RESULTS: Significant differences in leptin levels and homeostasis model assessment of insulin resistance (HOMA-IR) related to smoking status were observed (P=0.001 and P=0.008, respectively). The multivariate-adjusted geometric means of leptin in current, past and never smokers were 3.88, 4.08 and 4.12 ng/ml, respectively, while the means of HOMA-IR were 1.64, 1.61 and 1.49, respectively. The age-, body mass index-, and other lifestyle-adjusted prevalences of diabetes in current and never smokers were 9.2 and 4.7%, respectively. That of current smokers was significantly higher than in never smokers (P<0.001). The dose-dependent association found between the intensity of smoking and leptin levels in current smokers was statistically significant (P=0.030). CONCLUSIONS: The present finding may explain in part an association among smoking, leptin levels and diabetes. Smoking is one of the important modifiable risk factors for the prevention of diabetes.

  193. Association between low birth weight and elevated white blood cell count in adulthood within a Japanese population. 査読有り

    Wada K, Tamakoshi K, Ouyang P, Otsuka R, Mitsuhashi H, Takefuji S, Matsushita K, Sugiura K, Hotta Y, Toyoshima H, Yatsuya H.

    Circ J   72 巻 ( 5 ) 頁: 757-763   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  194. Active smoking, passive smoking, and breast cancer risk: findings from the Japan Collaborative Cohort Study for Evaluation of Cancer Risk. 査読有り

    Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, Yatsuya H, Nishio K, Suzuki S, Tokudome S, Yamamoto A, Toyoshima H, Mori M, Tamakoshi A; Japan Collaborative Cohort Study Group for Evaluation of Cancer Risk.

    J Epidemiol   18 巻 ( 2 ) 頁: 77-83   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  195. Eating fast leads to insulin resistance: findings in middle-aged Japanese men and women. 査読有り

    Otsuka R, Tamakoshi K, Yatsuya H, Wada K, Matsushita K, OuYang P, Hotta Y, Takefuji S, Mitsuhashi H, Sugiura K, Sasaki S, Kral JG, Toyoshima H.

    Prev Med   46 巻 ( 2 ) 頁: 154-159   2008年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  196. Smoking status and adiponectin in healthy Japanese men and women. 査読有り

    Takefuji S, Yatsuya H, Tamakoshi K, Otsuka R, Wada K, Matsushita K, Sugiura K, Hotta Y, Mitsuhashi H, Oiso Y, Toyoshima H.

    Prev Med   45 巻 ( 6 ) 頁: 471-475   2007年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  197. High-sensitivity C-reactive protein is quite low in Japanese men at high coronary risk. 査読有り

    Matsushita K, Yatsuya H, Tamakoshi K, Yang PO, Otsuka R, Wada K, Mitsuhashi H, Hotta Y, Kondo T, Murohara T, Toyoshima H.

    Circ J   71 巻 ( 6 ) 頁: 820-825   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  198. Adiponectin level and left ventricular hypertrophy in Japanese men. 査読有り

    Mitsuhashi H, Yatsuya H, Tamakoshi K, Matsushita K, Otsuka R, Wada K, Sugiura K, Takefuji S, Hotta Y, Kondo T, Murohara T, Toyoshima H.

    Hypertension   49 巻 ( 6 ) 頁: 1448-1454   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  199. Risk factors for first acute myocardial infarction attack assessed by cardiovascular disease registry data in Aichi Prefecture. 査読有り

    Kondo Y, Toyoshima H, Yatsuya H, Hirose K, Morikawa Y, Ikedo N, Masui T, Tamakoshi K.

    Nagoya J Med Sci   69 巻 ( 3-4 ) 頁: 139-147   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  200. A nested case-control study of stomach cancer incidence and serum superoxide dismutase activity in the Japan Collaborative Cohort study in Japan. 査読有り

    Pham TM, Fujino Y, Kikuchi S, Tamakoshi A, Yatsuya H, Kubo T, Matsuda S, Yoshimura T; JACC Study Group.

    Cancer Detect Prev   31 巻 ( 6 ) 頁: 431-435   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  201. Thermodynamic instability of siRNA duplex is a prerequisite for dependable prediction of siRNA activities. 査読有り

    Ichihara M, Murakumo Y, Masuda A, Matsuura T, Asai N, Jijiwa M, Ishida M, Shinmi J, Yatsuya H, Qiao S, Takahashi M, Ohno K.

    Nucleic Acids Res   35 巻 ( 18 ) 頁: e123   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  202. Pathophysiologic mechanisms of obesity and related metabolic disorders: an epidemiologic study using questionnaire and serologic biomarkers. 招待有り

    Yatsuya H.

    J Epidemiol   17 巻 ( 5 ) 頁: 141-146   2007年

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    担当区分:筆頭著者   記述言語:英語  

  203. Reduction of inner retinal thickness in patients with autosomal dominant optic atrophy associated with OPA1 mutations. 査読有り

    Ito Y, Nakamura M, Yamakoshi T, Lin J, Yatsuya H, Terasaki H.

    Invest Ophthalmol Vis Sci   48 巻 ( 9 ) 頁: 4079-4086   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  204. Direct comparison study between FDG-PET and IMP-SPECT for diagnosing Alzheimer's disease using 3D-SSP analysis in the same patients. 査読有り

    Nihashi T, Yatsuya H, Hayasaka K, Kato R, Kawatsu S, Arahata Y, Iwai K, Takeda A, Washimi Y, Yoshimura K, Mizuno K, Kato T, Naganawa S, Ito K.

    Radiat Med   25 巻 ( 6 ) 頁: 255-262   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  205. Consumption of soy foods and the risk of breast cancer: findings from the Japan Collaborative Cohort (JACC) Study. 査読有り

    Nishio K, Niwa Y, Toyoshima H, Tamakoshi K, Kondo T, Yatsuya H, Yamamoto A, Suzuki S, Tokudome S, Lin Y, Wakai K, Hamajima N, Tamakoshi A.

    Cancer Causes Control   18 巻 ( 8 ) 頁: 801-808   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  206. High-sensitivity C-reactive protein is quite low in Japanese men at high coronary risk. 査読有り

    Matsushita K, Yatsuya H, Tamakoshi K, Yang PO, Otsuka R, Wada K, Mitsuhashi H, Hotta Y, Kondo T, Murohara T, Toyoshima H.

      71 巻 ( 6 ) 頁: 820-825   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  207. A nested case-control study of stomach cancer and serum insulin-like growth factor (IGF)-1, IGF-2 and IGF-binding protein (IGFBP)-3. 査読有り

    Pham TM, Fujino Y, Kikuchi S, Tamakoshi A, Yatsuya H, Matsuda S, Yoshimura T; JACC Study Group.

    Eur J Cancer   43 巻 ( 10 ) 頁: 1611-1616   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  208. A new method of blood sampling reduces pain for newborn infants: a prospective, randomized controlled clinical trial. 査読有り

    Sato Y, Fukasawa T, Hayakawa M, Yatsuya H, Hatakeyama M, Ogawa A, Kuno K.

    Early Hum Dev   83 巻 ( 6 ) 頁: 389-394   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  209. The transition to menopause reinforces adiponectin production and its contribution to improvement of insulin-resistant state. 査読有り

    Tamakoshi K, Yatsuya H, Wada K, Matsushita K, Otsuka R, Yang PO, Sugiura K, Hotta Y, Mitsuhashi H, Takefuji S, Kondo T, Toyoshima H.

    Clin Endocrinol (Oxf)   66 巻 ( 1 ) 頁: 65-71   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  210. Lung cancer mortality and body mass index in a Japanese cohort: findings from the Japan Collaborative Cohort Study (JACC Study). 査読有り

    Kondo T, Hori Y, Yatsuya H, Tamakoshi K, Toyoshima H, Nishino Y, Seki N, Ito Y, Suzuki K, Ozasa K, Watanabe Y, Ando M, Wakai K, Tamakoshi A.

    Cancer Causes Control   18 巻 ( 2 ) 頁: 229-234   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  211. Psychological attitudes and risk of breast cancer in Japan: a prospective study. 査読有り

    Wakai K, Kojima M, Nishio K, Suzuki S, Niwa Y, Lin Y, Kondo T, Yatsuya H, Tamakoshi K, Yamamoto A, Tokudome S, Toyoshima H, Tamakoshi A; for the JACC Study Group.

    Cancer Causes Control   18 巻 ( 3 ) 頁: 259-267   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  212. Psychological factors and insomnia among male civil servants in Japan. 査読有り

    Murata C, Yatsuya H, Tamakoshi K, Otsuka R, Wada K, Toyoshima H.

    Sleep Med   8 巻 ( 3 ) 頁: 209-217   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  213. A nested case-control study of stomach cancer and serum insulin-like growth factor (IGF)-1, IGF-2 and IGF-binding protein (IGFBP)-3. 査読有り

    Pham TM, Fujino Y, Kikuchi S, Tamakoshi A, Yatsuya H, Matsuda S, Yoshimura T; The JACC Study Group.

    Eur J Cancer   43 巻 ( 10 ) 頁: 1611-1616   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  214. Impact of intensive-care-unit(ICU)-acquired ventilator-associated pneumonia(VAP) on hospital mortality: a matched-paired case-control study. 査読有り

    Uno H, Takezawa J, Yatsuya H, Suka M, Yoshida K.

    Nagoya J Med Sci   69 巻 ( 1-2 ) 頁: 29-36   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  215. White blood cell count and risk of all-cause and cardiovascular mortality in nationwide sample of Japanese--results from the NIPPON DATA90. 査読有り

    Tamakoshi K, Toyoshima H, Yatsuya H, Matsushita K, Okamura T, Hayakawa T, Okayama A, Ueshima H; NIPPON DATA90 Research Group.

    Circ J   71 巻 ( 4 ) 頁: 479-485   2007年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  216. Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men. 査読有り

    Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Zhang H, Sugiura K, Kondo T, Murohara T, Toyoshima H.

    Atherosclerosis   188 巻   頁: 184-189   2006年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  217. Perceived psychological stress and serum leptin concentrations in Japanese men. 査読有り

    Otsuka R, Yatsuya H, Tamakoshi K, Matsushita K, Wada K, Toyoshima H.

    Obesity (Silver Spring)   14 巻 ( 10 ) 頁: 1832-1838   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  218. Inverse association between adiponectin and C-reactive protein in substantially healthy Japanese men. 査読有り

    Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Zhang H, Sugiura K, Kondo T, Murohara T, Toyoshima H.

    Atherosclerosis   188 巻 ( 1 ) 頁: 184-189   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  219. Comparison of circulating adiponectin and proinflammatory markers regarding their association with metabolic syndrome in Japanese men. 査読有り

    Matsushita K, Yatsuya H, Tamakoshi K, Wada K, Otsuka R, Takefuji S, Sugiura K, Kondo T, Murohara T, Toyoshima H.

    Arterioscler Thromb Vasc Biol   26 巻 ( 4 ) 頁: 871-876   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  220. Birth weight and adult hypertension: cross-sectional study in a Japanese workplace population. 査読有り

    Tamakoshi K, Yatsuya H, Wada K, Matsushita K, Otsuka R, Yang PO, Sugiura K, Hotta Y, Mitsuhashi H, Kondo T, Toyoshima H.

    Circ J   70 巻 ( 3 ) 頁: 262-267   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  221. Association between parental histories of hypertension, diabetes and dyslipidemia and the clustering of these disorders in offspring. 査読有り

    Wada K, Tamakoshi K, Yatsuya H, Otsuka R, Murata C, Zhang H, Takefuji S, Matsushita K, Sugiura K, Toyoshima H.

    Prev Med   42 巻 ( 5 ) 頁: 358-363   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  222. Determinants of self-rated health: could health status explain the association between self-rated health and mortality? 査読有り

    Murata C, Kondo T, Tamakoshi K, Yatsuya H, Toyoshima H.

    Arch Gerontol Geriatr   43 巻 ( 3 ) 頁: 369-380   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  223. Plasma fibrinogen levels and cardiovascular risk factors in Japanese schoolchildren. 査読有り

    Fujii C, Sakakibara H, Kondo T, Yatsuya H, Tamakoshi K, Toyoshima H.

    J Epidemiol   16 巻 ( 2 ) 頁: 64-70   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  224. Low birth weight is associated with reduced adiponectin concentration in adult. 査読有り

    Tamakoshi K, Yatsuya H, Wada K, Matsushita K, Otsuka R, Sugiura K, Kondo T, Toyoshima H.

    Ann Epidemiol   16 巻 ( 9 ) 頁: 669-674   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  225. Eating fast leads to obesity: findings based on self-administered questionnaires among middle-aged Japanese men and women. 査読有り

    Otsuka R, Tamakoshi K, Yatsuya H, Murata C, Sekiya A, Wada K, Zhang HM, Matsushita K, Sugiura K, Takefuji S, OuYang P, Nagasawa N, Kondo T, Sasaki S, Toyoshima H.

    Journal of Epidemiology   16 巻 ( 3 ) 頁: 117-124   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  226. Factors associated with life space among community-living rural elders in Japan. 査読有り

    Murata C, Kondo T, Tamakoshi K, Yatsuya H, Toyoshima H.

    Public Health Nurs   23 巻 ( 4 ) 頁: 324-331   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  227. Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability. 査読有り

    Shirai K, Ohmiya N, Taguchi A, Mabuchi N, Yatsuya H, Itoh A, Hirooka Y, Niwa Y, Mori N, Goto H.

    J Gastroenterol Hepatol   21 巻 ( 7 ) 頁: 1129-1135   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  228. Seasonal variations of acute massive submacular haemorrhage associated with age-related macular degeneration. 査読有り

    Iguchi Y, Ito Y, Kikuchi M, Ishikawa K, Oshima H, Yatsuya H, Terasaki H.

    Br J Ophthalmol   90 巻 ( 10 ) 頁: 1256-1258   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  229. Factors related to frequency of engaging in outside activities among elderly persons living an independent life at home. 査読有り

    Ishikawa M, Tamakoshi K, Yatsuya H, Suma K, Wada K, Otsuka R, Matsushita K, Zhang H, Murata C, Kondo T, Toyoshima H.

    Nagoya J Med Sci   68 巻 ( 3-4 ) 頁: 121-130   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  230. HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam. 査読有り

    Tran TM, Nguyen HT, Yatsuya H, Hamajima N, Nishimura A, Ito K.

    BMC Public Health   10 巻 ( 6 ) 頁: 248   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  231. A positive association between leptin and blood pressure of normal range in Japanese men. 査読有り

    Wada K, Yatsuya H, Tamakoshi K, Otsukai R, Fujii C, Matsushita K, Sugiura K, Toyoshima H.

    Hypertens Res   29 巻 ( 7 ) 頁: 485-492   2006年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  232. Serum levels of insulin-like growth factor I, II, and binding protein 3, transforming growth factor beta-1, soluble fas ligand and superoxide dismutase activity in stomach cancer cases and their controls in the JACC Study. 査読有り

    Yatsuya H, Toyoshima H, Tamakoshi K, Tamakoshi A, Kondo T, Hayakawa N, Sakata K, Kikuchi S, Hoshiyama Y, Fujino Y, Mizoue T, Tokui N, Yoshimura T; JACC Study Group.

    Journal of Epidemiology   15 巻 ( S2 ) 頁: S120-S125   2005年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The prognosis of stomach cancer with advanced stage remains poor. New biomarkers of the disease that may contribute to establish the potential screening strategy would be of value for the early detection of individuals at high risk of the disease. METHODS: We conducted a prospective, nested case-control analysis among apparently healthy men and women who were followed for up to 8 years in the Japan Collaborative Cohort (JACC) Study, to evaluate serum levels of insulin-like growth factor I, II, and binding protein 3 (IFG-I, IGF-II, and IGFBP-3), transforming growth factorbeta-1 (TGFbeta1), soluble fas (sFas) and superoxide dismutase activity (SOD) in 210 stomach cancer cases diagnosed in the JACC Study in relation to those levels in their 410 controls. RESULTS: Among 6 serum biomarkers tested for case-control differences, only sFas level in female stomach cancer cases was significantly higher than that of controls (2.22 pg/ml vs. 2.04 pg/mL, respectively; P=0.013 by two-way analysis of covariance controlling for matching variable). CONCLUSION: None of the biomarkers consistently predicted future risk of stomach cancer in both men and women in the present analysis. Serum sFas level in women, however, should be studied much more thoroughly whether it provides meaningful refinement of risk stratification, or it elucidate the mechanisms of tumorigenesis in women.

  233. Cigarette smoking and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort study. 査読有り

    Niwa Y, Wakai K, Suzuki S, Tamakoshi K, Lin Y, Yatsuya H, Kondo T, Nishio K, Yamamoto A, Tokudome S, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

    J Obstet Gynaecol Res   31 巻 ( 2 ) 頁: 144-51   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  234. Prospective study of alcohol consumption and breast cancer risk in Japanese women. 査読有り

    Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, Yatsuya H, Nishio K, Suzuki S, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A.

    Int J Cancer   116 巻 ( 5 ) 頁: 779-83   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  235. Validity of self-reported height and weight in a Japanese workplace population. 査読有り

    Wada K, Tamakoshi K, Tsunekawa T, Otsuka R, Zhang H, Murata C, Nagasawa N, Matsushita K, Sugiura K, Yatsuya H, Toyoshima H.

    Int J Obes Relat Metab Disord   29 巻 ( 9 ) 頁: 1093-9   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  236. Effects of social relationships on mortality among the elderly in a Japanese rural area: an 88-month follow-up study. 査読有り

    Murata C, Takaaki K, Hori Y, Miyao D, Tamakoshi K, Yatsuya H, Sakakibara H, Toyoshima H.

    J Epidemiol   15 巻 ( 3 ) 頁: 78-84   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  237. Gender difference of sudden death 招待有り

    Tamakoshi K, Toyoshima H, Yatsuya H.

    Nippon Rinsho   63 巻 ( 7 ) 頁: 1284-8   2005年

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    記述言語:日本語  

  238. Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan. 査読有り

    Tamakoshi K, Toyoshima H, Wakai K, Kojima M, Suzuki K, Watanabe Y, Hayakawa N, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki S, Kawado M, Ozasa K, Ito Y, Tamakoshi A.

    Oncology   68 巻 ( 4-6 ) 頁: 454-61   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  239. Green tea and stomach cancer--a short review of prospective studies. 査読有り

    Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Yoshimura T; JACC Study Group.

    J Epidemiol   15 巻 ( S2 ) 頁: S109-12   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  240. Cigarette smoking and mortality due to stomach cancer: findings from the JACC Study. 査読有り

    Fujino Y, Mizoue T, Tokui N, Kikuchi S, Hoshiyama Y, Toyoshima H, Yatsuya H, Sakata K, Tamakoshi A, Ide R, Kubo T, Yoshimura T; JACC Study Group.

    J Epidemiol   15 巻 ( S2 ) 頁: S113-S119   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  241. Serum pepsinogen values and Helicobacter pylori status among control subjects of a nested case-control study in the JACC study. 査読有り

    Kikuchi S, Yagyu K, Obata Y, Yingsong L, Yatsuya H, Hoshiyama Y, Kondo T, Sakata K, Mizoue T, Tokui N, Fujino Y, Tamakoshi A, Toyoshima H, Ishibashi T, Hayakawa N, Yoshimura T; JACC Study Group.

    J Epidemiol   15 巻 ( S2 ) 頁: S126-S133   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  242. Mortality and incidence rates of stomach cancer in the JACC Study. 査読有り

    J Epidemiol   15 巻 ( S2 ) 頁: S89-S97   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  243. Dietary habits and stomach cancer risk in the JACC Study. 査読有り

    Tokui N, Yoshimura T, Fujino Y, Mizoue T, Hoshiyama Y, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Kubo T, Tamakoshi A; JACC Study Group.

    J Epidemiol   15 巻 ( S2 ) 頁: S98-S108   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  244. Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. 査読有り

    Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A; JACC Study Group.

    Cancer Sci   96 巻 ( 9 ) 頁: 590-599   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  245. Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study. 査読有り

    Niwa Y, Yatsuya H, Tamakoshi K, Nishio K, Kondo T, Lin Y, Suzuki S, Wakai K, Tokudome S, Yamamoto A, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

    J Obstet Gynaecol Res   31 巻 ( 5 ) 頁: 452-458   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  246. Association between serum leptin concentration and white blood cell count in middle-aged Japanese men and women. 査読有り

    Mabuchi T, Yatsuya H, Tamakoshi K, Otsuka R, Nagasawa N, Zhang H, Murata C, Wada K, Ishikawa M, Hori Y, Kondo T, Hashimoto S, Toyoshima H.

    Diabetes Metab Res Rev   21 巻 ( 5 ) 頁: 441-7   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  247. 出生時体重と成人期の生活習慣病との関連-胎児期起源仮説- 招待有り

    玉腰浩司、八谷寛、大塚礼、和田恵子、張恵明、豊嶋英明.

    現代医学   52 巻   頁: 321-325   2005年

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    記述言語:日本語  

  248. 突然死と性差 招待有り

    玉腰浩司、豊嶋英明、八谷寛.

    日本臨床   63 巻   頁: 1284-1288   2005年

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    記述言語:日本語  

  249. 肥満の健康影響 招待有り

    八谷寛、玉腰浩司、豊嶋英明.

    現代医学   52 巻   頁: 521-526   2005年

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    担当区分:筆頭著者   記述言語:日本語  

  250. 肥満の科学的解明とエビデンスに基づいた対策・指導 招待有り

    八谷寛、松下邦洋、玉腰浩司、大塚礼、和田恵子、豊嶋英明.

    産業医学レビュー   18 巻   頁: 71-116   2005年

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    担当区分:筆頭著者   記述言語:日本語  

  251. 職域コホート男性における血清レプチン濃度と生活習慣との関連 査読有り

      63 巻   頁: 1284-1288   2005年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  252. Lack of an association between serum level of transforming growth factor beta -1 and stomach cancer risk in the JACC study.

    Yatsuya H, Tamakoshi A, Tamakoshi K, Hoshiyama Y, Fujino Y, Tokui N, Mizoue T, Kikuchi S, Sakata K, Hayakawa N, Kondo T, Toyoshima H, Yoshimura T.

    Asian Pacific Journal of Cancer Prevention   6 巻 ( 2 ) 頁: 170-176   2005年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Alterations in the serum concentration of transforming growth factor beta-1 (TGFbeta1) have been observed in gastric cancer patients. No study, however, has ever examined the association between the serum TGFbeta1 level and stomach cancer prospectively. We conducted a prospective, nested case-control analysis among apparently healthy men and women who were followed for up to 8 years in the JACC Study to assess whether serum level of total TGFbeta1 is associated with a subsequent risk of stomach cancer. The concentration of serum TGFbeta1 in previously collected blood samples was analyzed by ELISA for 209 individuals in whom a diagnosis of stomach cancer was documented, and for 409 controls matched with them for gender, age and study area. Baseline blood levels of TGFbeta1 were not related to the risk of stomach cancer in either men or women, a finding unchanged even after adjustment for potential confounders. The multivariate-adjusted odds ratio of stomach cancer in men and women was 1.10 (95% CI, 0.82 to 1.48) and 1.09 (95% CI, 0.80 to 1.48), respectively, for each increase of 1 SD in the TGFbeta1 value. In conclusion, serum TGFbeta1 levels were not associated with increased risks of subsequent stomach cancer.

  253. Familial aggregation and coaggregation of history of hypertension and stroke. 査読有り

    Kondo T, Toyoshima H, Tsuzuki Y, Hori Y, Yatsuya H, Tamakoshi K, Tamakoshi A, Ohno Y; JACC Study Group.

    J Hum Hypertens   19 巻 ( 2 ) 頁: 119-25   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  254. Long-term body weight fluctuation is associated with metabolic syndrome independent of current body mass index among Japanese men. 査読有り

    Zhang H, Tamakoshi K, Yatsuya H, Murata C, Wada K, Otsuka R, Nagasawa N, Ishikawa M, Sugiura K, Matsushita K, Hori Y, Kondo T, Toyoshima H.

    Circ J   69 巻 ( 1 ) 頁: 13-8   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  255. Impact of menstrual and reproductive factors on breast cancer risk in Japan: results of the JACC study. 査読有り

    Tamakoshi K, Yatsuya H, Wakai K, Suzuki S, Nishio K, Lin Y, Niwa Y, Kondo T, Yamamoto A, Tokudome S, Toyoshima H, Tamakoshi A; JACC Study Group.

    Cancer Sci   96 巻 ( 1 ) 頁: 57-62   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  256. Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study. 査読有り

    Niwa Y, Yatsuya H, Tamakoshi K, Nishio K, Kondo T, Lin Y, Suzuki S, Wakai K, Tokudome S, Yamamoto A, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

    J Obstet Gynaecol Res   31 巻 ( 5 ) 頁: 452-458   2005年

     詳細を見る

    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  257. Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. 査読有り

    Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A; JACC Study Group.

    Cancer Sci   96 巻 ( 9 ) 頁: 590-599   2005年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  258. Association of white blood cell count and clustered components of metabolic syndrome in Japanese men. 査読有り

    Nagasawa N, Tamakoshi K, Yatsuya H, Hori Y, Ishikawa M, Murata C, Zhang H, Wada K, Otsuka R, Mabuchi T, Kondo T, Toyoshima H.

    Circ J   68 巻 ( 10 ) 頁: 892-7   2004年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  259. 人間ドックの有効性と限界 招待有り

    玉腰浩司, 八谷寛, 豊嶋英明.

    総合臨床   53 巻   頁: 2435-2438   2004年

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    記述言語:日本語  

  260. 肥満女性と結腸癌 招待有り

    医学のあゆみ   208 巻   頁: 229-230   2004年

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    記述言語:日本語  

  261. 肥満を伴った高脂血症患者に対する運動療法の効果に関する研究 行動医学的アプローチを用いた運動習慣の定着による動脈硬化促進要因の改善に関する研究 招待有り

    下光輝一, 井上茂, 小田切優子, 高波嘉一, 豊嶋英明, 八谷寛, 玉腰浩司, 近藤高明, 井口ちよ

    医科学応用研究財団研究報告   21 巻   頁: 215-223   2004年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  262. 日本人男性における血清レプチン濃度と5年間追跡後の体重変化. 招待有り

    八谷寛, 玉腰浩司, 大塚礼, 間淵智子, 和田恵子, 張恵明, 村田千代栄, 石川美由紀, 近藤高明, 豊嶋英明.

    健康医科学研究助成論文集   19 巻   頁: 110-117   2004年

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  263. 肥満者における心血管疾患発症の過剰リスクを説明する新しい軸-血清レプチン値と白血球数の関連- 招待有り

    八谷寛, 淵智子, 大塚礼, 和田恵子, 長澤伸江, 張恵明, 村田千代栄, 石川美由紀, 堀容子, 近藤高明, 玉腰浩司, 豊嶋英明.

    健康管理事業団研究助成論文集   10 巻   頁: 19-25   2004年

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  264. Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: a nested case-control study. 査読有り

    Yatsuya H, Toyoshima H, Tamakoshi A, Kikuchi S, Tamakoshi K, Kondo T, Mizoue T, Tokui N, Hoshiyama Y, Sakata K, Hayakawa N, Yoshimura T; Japan Collaborative Cohort Study Group.

    British Journal of Cancer   91 巻 ( 5 ) 頁: 929-934   2004年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    We used 202 cases of stomach cancer and 394 controls nested within the Japan Collaborative Cohort Study For Evaluation of Cancer Risk (JACC study) to investigate whether family history has an independent effect on the risk of stomach cancer after controlling for the Helicobacter pylori infection. A positive history of stomach cancer in one or more first-degree relatives was associated with an increased risk of the disease in women, but not in men after controlling for H. pylori infection and other confounding variables. Women with both a family history and H. pylori infection were associated with more than five-fold increased risk of the disease (OR 5.10, 95% CI 1.58-16.5) compared to those without these factors. These results suggest the existence of inherited susceptibility to the disease in women, and that measurements of H. pylori infection together with the family history allow meaningful evaluation of risk beyond that provided by either factor alone.

  265. Serum phospholipid transfer protein mass as a possible protective factor for coronary heart diseases. 査読有り

    Yatsuya H, Tamakoshi K, Hattori H, Otsuka R, Wada K, Zhang H, Mabuchi T, Ishikawa M, Murata C, Yoshida T, Kondo T, Toyoshima H.

    Circulation Journal   68 巻 ( 1 ) 頁: 11-16   2004年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Phospholipid transfer protein (PLTP) can generate pre-beta high-density lipoprotein (HDL), an efficient acceptor of peripheral cholesterol, by mediating a process called HDL conversion. The transfer of phospholipids to immature HDL is also essential in maintaining reverse cholesterol transport. The phospholipid transfer activity of PLTP has been associated with various patho-physiological conditions; however, little information is available concerning the relationship between PLTP mass and disease. METHODS AND RESULTS: Using a sandwich enzyme-linked immunosorbent assay, PLTP concentration was measured and related to the risk of developing cardiovascular disease in a worksite-based cohort of Japanese men (n=2,567). Multiple linear regression analysis showed significant associations between PLTP and HDL cholesterol, triglycerides, low-density lipoprotein cholesterol, and body mass index (standardized beta=0.395, -0.191, -0.064, and -0.064, respectively; R(2)=0.31). During the follow-up period, there were 10 cases of coronary heart disease (CHD) and 7 of stroke. The multivariate adjusted relative risk of CHD was 0.46 (95% confidence interval, 0.20-1.07) for an increase of 1 standard deviation in the PLTP value (p=0.071). PLTP concentration was not related to the risk of stroke. CONCLUSIONS: The results of this prospective study indicate that the serum PLTP concentration would serve as a predictor of CHD, independent of HDL cholesterol, triglycerides and other established risk factors.

  266. A nested case-control study of stomach cancer in relation to green tea consumption in Japan. 査読有り

    Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T; Japan Collaborative Cohort Study Group.

    Br J Cancer   90 巻 ( 1 ) 頁: 135-8   2004年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  267. A prospective study of body size and colon cancer mortality in Japan: The JACC Study. 査読有り

    Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A; JACC Study Group.

    Int J Obes Relat Metab Disord   28 巻 ( 4 ) 頁: 551-8   2004年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  268. A prospective study on the possible association between having children and colon cancer risk: findings from the JACC Study. 査読有り

    Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A; JACC Study Group.

    Cancer Sci   95 巻 ( 3 ) 頁: 243-7   2004年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  269. A prospective study of reproductive and menstrual factors and colon cancer risk in Japanese women: findings from the JACC study. 査読有り

    Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Suzuki S, Kawado M, Ozasa K, Ito Y, Tamakoshi A; JACC Study Group.

    Cancer Sci   95 巻 ( 7 ) 頁: 602-7   2004年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  270. Association of flatfoot with pain, fatigue and obesity in Japanese over sixties. 査読有り

    Otsuka R, Yatsuya H, Miura Y, Murata C, Tamakoshi K, Oshiro K, Nishio N, Ishikawa M, Zhang HM, Shiozawa M, Kobayashi A, Ito M, Hori Y, Kondo T, Toyoshima H.

    Nippon Koshu Eisei Zasshi   50 巻 ( 10 ) 頁: 988-98   2003年10月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  271. Effect of tactile interference stimulation of the ear in human primary somatosensory cortex: a magnetoencephalographic study. 査読有り

    Nihashi T, Kakigi R, Hoshiyama M, Miki K, Kajita Y, Yoshida J, Yatsuya H.

    Clin Neurophysiol   114 巻 ( 10 ) 頁: 1866-78   2003年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  272. Long-term body weight variability is associated with elevated C-reactive protein independent of current body mass index among Japanese men. 査読有り

    Tamakoshi K, Yatsuya H, Kondo T, Ishikawa M, Zhang H, Murata C, Otsuka R, Mabuchi T, Hori Y, Zhu S, Yoshida T, Toyoshima H.

    Int J Obes Relat Metab Disord   27 巻 ( 9 ) 頁: 1059-65   2003年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  273. Aggregation of stomach cancer history in parents and offspring in comparison with other sites. 査読有り

    Kondo T, Toyoshima H, Tsuzuki Y, Hori Y, Yatsuya H, Tamakoshi K, Tamakoshi A, Ohno Y, Kikuchi S, Sakata K, Hoshiyama Y, Hayakawa N, Tokui N, Mizoue T, Yoshimura T.

    Int J Epidemiol     頁: 579-83   2003年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  274. Prospective study of screening for stomach cancer in Japan. 査読有り

    Mizoue T, Yoshimura T, Tokui N, Hoshiyama Y, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Fujino Y, Kaneko S; Japan Collaborative Cohort Study Group.

    Int J Cancer   106 巻 ( 1 ) 頁: 103-7   2003年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  275. The metabolic syndrome is associated with elevated circulating C-reactive protein in healthy reference range, a systemic low-grade inflammatory state. 査読有り

    Tamakoshi K, Yatsuya H, Kondo T, Hori Y, Ishikawa M, Zhang H, Murata C, Otsuka R, Zhu S, Toyoshima H.

    Int J Obes Relat Metab Disord   27 巻 ( 4 ) 頁: 443-9   2003年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  276. U-shaped association between white blood cell count and fasting plasma glucose level. 査読有り

    Tamakoshi K, Yatsuya H, Kondo T, Hori Y, Zhang H, Ishikawa M, Murata C, Otsuka R, Zhu S, Toyoshima H.

    Diabetes Care   26 巻 ( 3 ) 頁: 950   2003年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  277. The accuracy of long-term recall of past body weight in Japanese adult men. 査読有り

    Tamakoshi K, Yatsuya H, Kondo T, Hirano T, Hori Y, Yoshida T, Toyoshima H.

    Int J Obes Relat Metab Disord   27 巻 ( 2 ) 頁: 247-52   2003年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  278. Gender and age differences in lifestyle factors related to hypertension in middle-aged civil service employees. 査読有り

    Hori Y, Toyoshima H, Kondo T, Tamakoshi K, Yatsuya H, Zhu S, Kawamura T, Toyama J, Okamoto N.

    J Epidemiol   13 巻 ( 1 ) 頁: 38-47   2003年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  279. Reproducibility and validity of a simple checklist-type questionnaire for food intake and dietary behavior. 査読有り

    Yatsuya H, Ohwaki A, Tamakoshi K, Wakai K, Koide K, Otsuka R, Mabuchi T, Murata C, Zhang H, Ishikawa M, Kondo T, Toyoshima H.

    Journal of Epidemiology   13 巻 ( 5 ) 頁: 235-245   2003年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: A simple, reliable, and valid food questionnaire is needed in clinical dietary assessments, community health education, and multi-purpose epidemiologic studies to obtain a crude measure of dietary intake. METHODS: To assess the validity and reproducibility of a simple 4-point scale food intake and behavior checklist, it was compared to two 3-day weighed dietary records. The FBC was administered to 47 students of a dietician course and their parents (n = 94) over a 9-month interval to assess the reproducibility. The mean intakes of selected food groups assessed by the two dietary records completed between food intake and behavior checklists were compared to the responses to the food intake and behavior checklist to assess its validity. RESULTS: The kappa statistics for reproducibility ranged from 0.25 for confectionaries to 0.63 for a preference for fatty foods (median, 0.39). There was a reasonable level of correlation between the dietary record and the food intake and behavior checklist in the intake of eggs, milk, and fruits (r = 0.53, 0.56, and 0.50, respectively). There was a weaker but still significant correlation in the intake of vegetables, and alcohol (r = 0.31 and 0.45, respectively). No significant correlation was observed in the intake of meat, fish, confectionaries, and soft drinks. However, those who reported consuming mainly fish rather than meat were found to eat significantly less meat and animal fat. Similarly, those who did not prefer fatty foods consumed significantly less meat, animal fat, and polyunsaturated fatty acids. CONCLUSIONS: This simple food checklist was useful in collecting data on egg, milk, and fruit consumption. Assessing intake frequency of vegetables, meat or fish with the FBC may be useful in screening high- or low-intake individuals.

  280. クリティカルパスの実際: 高血圧クリティカルパス 招待有り

    堀容子, 齊藤郁夫, 鈴木一夫, 長谷川敏彦, 星野純子, 八谷寛, 玉腰浩司, 近藤高明, 豊嶋英明, 村地俊二.

    成人病と生活習慣病   33 巻   頁: 687-692   2003年

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    記述言語:日本語  

  281. わが国における心筋梗塞と脳卒中 疫学的検討:高脂血症の疫学と心筋梗塞,脳卒中 招待有り

    玉腰浩司, 八谷寛, 近藤高明, 豊嶋英明.

    循環器科   54 巻   頁: 372-379   2003年

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    記述言語:日本語  

  282. 肥満と動脈硬化:肥満度の指標" 招待有り

    八谷寛, 玉腰浩司, 近藤高明, 豊嶋英明.

    動脈硬化予防   2 巻   頁: 17-23   2003年

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    担当区分:筆頭著者   記述言語:日本語  

  283. 後期高齢者における転倒関連要因についての検討 サテライト型デイサービス利用者を対象として 査読有り

    堀容子, 近藤高明, 玉腰浩司, 八谷寛, 滝益栄, 小林督子, 北澤百合子, 代田妙子, 豊嶋英明.

    日本赤十字愛知短期大学紀要   14 巻   頁: 139-146   2003年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  284. 地域在住高齢者における扁平足と足の自覚症状,及び肥満との関連 査読有り

    大塚礼, 八谷寛, 三浦弥生, 村田千代栄, 玉腰浩司, 大城宏治, 西尾直樹, 石川美由紀, 張恵明, 塩澤まゆみ, 小林あゆみ, 伊藤美果, 堀容子, 近藤高明, 豊嶋英明.

    日本公衆衛生雑誌   50 巻   頁: 988-998   2003年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  285. Association between weight fluctuation and fasting insulin concentration in Japanese men. 査読有り

    Yatsuya H, Tamakoshi K, Yoshida T, Hori Y, Zhang H, Ishikawa M, Zhu S, Kondo T, Toyoshima H.

    International Journal of Obesity and Related Metabolic Disorders   27 巻 ( 4 ) 頁: 478-483   2003年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVE: To investigate whether long-term weight fluctuation is associated with the fasting serum insulin concentration. DESIGN AND SUBJECTS: Weight histories of 1932 male Japanese workers aged 40-59 y were analyzed in relation to their current fasting serum insulin concentration. MEASUREMENTS: Individual weight fluctuation was calculated by root mean square error (RMSE) along the linear regression line of weight measured at five to six different ages. RESULTS: The mean RMSE and fasting insulin concentration were 1.22 kg and 4.5 microU/ml, respectively. The multivariate adjusted insulin level became higher with the increase in weight fluctuation. Subanalysis stratified by current body mass index (BMI) showed that the multivariate adjusted insulin level in individuals in the top quartile of fluctuation was 4.3 microU/ml, against 3.9 microU/ml in those in the bottom quartile (P=0.018, analysis of covariance (ANCOVA)) in the normal weight subgroup with current BMI below 25 kg/m(2). In the overweight subgroup with BMI 25 kg/m(2) or above, the level was 6.9 microU/ml in individuals in the top quartile and 6.2 microU/ml in those in the bottom quartile (P=0.054, ANCOVA). CONCLUSION: The results suggest that weight fluctuation increases the risk of developing hyperinsulinemia. Prospective observations together with measurement of changes in adiposity are needed for confirmation.

  286. A prospective study of stomach cancer death in relation to green tea consumption in Japan. 査読有り

    Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T; Japan Collaborative Cohort Study Group.

    Br J Cancer   87 巻 ( 3 ) 頁: 309-13   2002年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  287. Role of the anterolateral thigh flap in head and neck reconstruction: advantages of moderate skin and subcutaneous thickness. 査読有り

    Nakayama B, Hyodo I, Hasegawa Y, Fujimoto Y, Matsuura H, Yatsuya H, Torii S.

    J Reconstr Microsurg   18 巻 ( 3 ) 頁: 141-6   2002年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  288. Short- and long-term reliability of information on previous illness and family history as compared with that on smoking and drinking habits in questionnaire surveys. 査読有り

    Zhu S, Toyoshima H, Kondo T, Tamakoshi K, Yatsuya H, Hori Y, Tsubono Y, Nishino Y, Tsuji I, Hisamichi S.

    J Epidemiol   12 巻 ( 2 ) 頁: 120-5   2002年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  289. Family history and the risk of stomach cancer death in Japan: differences by age and gender. 査読有り

    Yatsuya H, Toyoshima H, Mizoue T, Kondo T, Tamakoshi K, Hori Y, Tokui N, Hoshiyama Y, Kikuchi S, Sakata K, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T.

    International Journal of Cancer   97 巻 ( 5 ) 頁: 688-694   2002年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Familial aggregation of stomach cancer has long been observed. The effect on disease risk of family history and its magnitude according to the type of affected relatives, however, is not well known. We conducted a prospective analysis using the JACC study (Japan Collaborative Cohort Study For Evaluation of Cancer Risk, sponsored by Monbusho) data. During the follow-up period, 662 stomach cancer deaths were documented. A positive history of stomach cancer in one or more first-degree relatives was associated with a significantly increased risk of death from the disease in both men (RR 1.60; 95% CI 1.11-2.31) and women (RR 2.47; 95% CI 1.50-4.06). In the subanalysis stratified by age, the association between positive family history and stomach cancer was stronger in the age group from 40-59 (RR 2.62; 95% CI 1.34-5.11 for men and RR 5.88; 95% CI 2.70-12.82 for women) than in the age group from 60-79 (RR 1.31; 95% CI 0.84-2.05 for men and RR 1.44; 95% CI 0.72-2.88 for women). In the age group from 40-59, men with father's history and women with mother's and sister's history of the disease had a significantly increased risk (RR 3.14; 95% CI 1.51-6.55, RR 10.46; 95% CI 4.54-24.12, RR 13.39; 95% CI 3.89-46.12, respectively). When 2 or more family members were affected, the increment in the risk was prominent especially in women (RR 9.45; 95% CI 4.46-20.05). These results suggest the existence of a certain subtype of stomach cancer that is inherited more often by women from one generation to the next in gender-influenced fashion. Any preventive strategy should take into account the degree of individual susceptibility.

  290. Trends in the mortality (1950-1997) and incidence (1975-1993) of malignant ovarian neoplasm among Japanese women: analyses by age, time, and birth cohort. 査読有り

    Tamakoshi K, Kondo T, Yatsuya H, Hori Y, Kikkawa F, Toyoshima H.

    Gynecol Oncol   83 巻 ( 1 ) 頁: 64-71   2001年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  291. 若年者の死亡について 招待有り

    玉腰浩司、八谷寛、堀容子、近藤高明、豊嶋英明.

    現代医学   49 巻   頁: 169-173   2001年

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    記述言語:日本語  

  292. 産業保健における循環器疾患の一次予防対策 招待有り

    豊嶋英明、八谷寛、近藤高明、玉腰浩司.

    産業医学レビュー   13 巻   頁: 155-182   2001年

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    記述言語:日本語  

  293. A case of eosinophilic peritonitis in which ascites interleukin 5 presented at a high level.Hepatogastroenterology. 査読有り

    Yoshikane H, Yatsuya H, Sakakibara A, Hidano H, Arisawa T, Goto H.

    Hepatogastroenterology   47 巻 ( 36 ) 頁: 1588-9   2000年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

  294. 成人における循環器疾患:進展とその予防. その1: 心疾患 招待有り

    豊嶋英明、八谷寛.

    循環器専門医   8 巻   頁: 55-62   2000年

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    記述言語:日本語  

  295. 職域大規模集団における健診成績のデータベース化とバイオマテリアル長期保存における生活習慣病の予防対策 高脂血症者における食習慣の変容に関する横断的解析結果 招待有り

    八谷寛, 近藤高明, 堀容子, 玉腰浩司, 朱善寛, 川村孝, 吉田勉, 外山淳治, 岡本登, 島正吾, 豊嶋英明.

    協栄生命健康事業団研究助成論文集   15 巻   頁: 65-73   1999年

     詳細を見る

    担当区分:筆頭著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

  296. 発展途上国における下痢症の現状とその対策についての考察" 査読有り

    八谷寛, 豊嶋英明, 宮尾克, 肥田野等.

    社会医学研究   17 巻   頁: 47-51   1999年

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    担当区分:筆頭著者   記述言語:日本語  

  297. 日本の疾病負担と障害調整生存年(DALY) 査読有り

    福田吉治, 長谷川敏彦, 八谷寛, 田端航也.

    厚生の指標   46 巻   頁: 28-33   1999年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

▼全件表示

書籍等出版物 10

  1. 肥満の疫学

    小林身哉、八谷寛、小林邦彦監訳( 担当: 共著)

    名古屋大学出版会  2010年10月 

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    記述言語:日本語

  2. アディポネクチンとその受容体-抗生活習慣病ホルモンの全貌-門脇孝編(心肥大とアディポネクチン)

    三橋弘嗣、八谷寛、室原豊明、豊嶋英明、玉腰浩司( 担当: 共著)

    フジメディカル出版  2008年5月 

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    記述言語:日本語

  3. 動脈硬化・老年病予防健診マニュアル(胸部X線(心胸郭比))

    八谷寛、豊嶋英明. 小澤秀樹編( 担当: 共著)

    メジカルビュー社  2001年 

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    記述言語:日本語

  4. 循環器病予防ハンドブック(胸写・心電図)

    豊嶋英明、八谷寛、堀容子. 日本循環器管理研究協議会編.( 担当: 共著)

    保健同人社  2003年 

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    記述言語:日本語

  5. 循環器疾患の予防・管理・治療マニュアル(胸写・心電図)

    豊嶋英明、八谷寛、堀容子.日本循環器管理研究協議会編.( 担当: 共著)

    保健同人社  2003年 

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    記述言語:日本語

  6. がん予防の最前線(胃がん)

    八谷寛, 星山佳治, 菊地正悟, 藤野善久, 吉村健清. 田島和雄監修( 担当: 共著)

    昭和堂  2005年 

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    記述言語:日本語

  7. JACC Study −これまでの成果とあゆみ− 査読有り

    松永眞章、王超辰、八谷寛( 担当: 共著 ,  範囲: 脳血管疾患)

    予防医学広報事業団(⻘⽊平⼋郎・國雄記念)  2021年3月  ( ISBN:978-4-9911825-0-1

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    記述言語:日本語

  8. テキスト健康科学

    八谷寛, 太田充彦(担当:分担執筆, 範囲:第4章 社会と健康)( 担当: 共著)

    南江堂  2017年2月 

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    記述言語:日本語 著書種別:教科書・概説・概論

  9. テキスト健康科学

    八谷寛, 太田充彦( 担当: 分担執筆 ,  範囲: 第4章 社会と健康)

    南江堂  2017年2月 

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  10. 循環器病健康診査の手技と判定基準:肥満(循環器病予防ハンドブック 第7版)

    八谷寛、藤吉朗( 担当: 共著)

    保健同人社  2014年7月 

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    記述言語:日本語 著書種別:学術書

▼全件表示

MISC 51

  1. Increasing Role of Overweight/Obesity as the Determinant of Hypertension and the Consequent Cardiovascular Diseases in Japan. 招待有り 国際誌

    Yatsuya H  

    Journal of atherosclerosis and thrombosisadvpub 巻 ( 0 )   2022年7月

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    担当区分:筆頭著者, 最終著者, 責任著者   記述言語:英語   掲載種別:記事・総説・解説・論説等(学術雑誌)   出版者・発行元:一般社団法人 日本動脈硬化学会  

    DOI: 10.5551/jat.ED212

    PubMed

    CiNii Research

  2. Health of university students under job and financial insecurity during COVID-19 pandemic. 招待有り 国際誌

    Yatsuya H, Ishitake T  

    Journal of occupational health63 巻 ( 1 ) 頁: e12223   2021年1月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:記事・総説・解説・論説等(学術雑誌)   出版者・発行元:Journal of Occupational Health  

    DOI: 10.1002/1348-9585.12223

    Scopus

    PubMed

    CiNii Research

  3. 安全衛生担当労働者における加熱式タバコの利用状況

    加藤 善士, 太田 充彦, 八谷 寛  

    厚生の指標67 巻 ( 6 ) 頁: 23 - 28   2020年6月

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    記述言語:日本語   出版者・発行元:(一財)厚生労働統計協会  

    目的 職域では受動喫煙対策とともに喫煙労働者への禁煙指導が課題となっている。日本の職域における加熱式タバコの使用実態を報告した論文は少ない。本研究の目的は,職域における加熱式タバコの使用実態を把握し,喫煙対策の実施につながる知見を得ることである。方法 某労働災害防止団体の地方センターにおいて2019年4月〜6月末の3ヵ月間に開催した安全衛生教育受講者(819人)を対象にした自記式質問紙調査を実施した。喫煙率,加熱式タバコ利用状況,年齢,性別,役職,企業規模,喫煙習慣との関連を調べた。回答者741人のうち,男性回答者で分析に必要な項目に欠損がなかった653人を解析した。結果 喫煙率は37.8%(247人)であった。現喫煙者割合は40〜49歳で高く(40.1%),過去喫煙者割合は50歳以上で高く(37.8%),非喫煙者割合は40歳未満で高かった(49.1%)(p<0.001)。役職,企業規模と現喫煙,過去喫煙,非喫煙の割合に有意な関連は認めなかった。現喫煙者247人の内,加熱式タバコのみを利用する者が67人(現喫煙者の27.1%),加熱式タバコと通常のタバコとの併用者が55人(現喫煙者の22.3%)であった。加熱式タバコの利用状況(加熱式のみ,併用,通常のタバコのみ)と年齢,役職,企業規模との間に統計学的に有意な関連は認めなかった。加熱式タバコの利用理由は「においが少ない」(67.2%),「煙が少ない」(47.5%),「火の心配が少ない」(43.4%),「自分の健康被害が少ないと思う」(35.2%),「周囲の健康被害が少ないと思う」(34.4%)であった。結論 男性労働者の喫煙率には年齢による差はあったが,企業規模や役職による差はなかった。男性労働者の加熱式タバコの利用は20%程度で,全喫煙者の約半分であった。本研究では,健康被害よりもにおいや火に関連した危険を理由として加熱式タバコを利用する者が多かった。事業場においては,通常のタバコへの喫煙対策と併せて加熱式タバコへの対策も行うことが望まれる。(著者抄録)

    researchmap

  4. 中年期の空腹時血糖と高齢期の認知機能との関連:愛知職域コホート研究

    霜田真子, 八谷寛, 加藤綾子, 金子佳世, 中川威, 河野直子, 大塚礼, 太田充彦, 内藤久雄, 李媛英, 市野直浩, 山田宏哉, 江啓発, 平川仁尚, 玉腰浩司, 青山温子, 青山温子  

    日本疫学会学術総会講演集(Web)30th 巻   2020年

     詳細を見る

  5. 生涯にわたる循環器疾患の個人リスクおよび集団のリスク評価ツールの開発を目的とした大規模コホート統合研究 統合研究リスクエンジン2(個人の10年リスク)個人の10年以内の循環器疾患の予測リスクの開発

    八谷寛, 李媛英, 田中佐智子, 村上義孝, 三浦克之, 辻一郎, 宮本恵宏, 坂田清美, 磯博康, 岡山明, 岡村智教  

    生涯にわたる循環器疾患の個人リスクおよび集団のリスク評価ツールの開発を目的とした大規模コホート統合研究 令和元年度 総括・分担研究報告書(Web)   2020年

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    担当区分:責任著者   記述言語:日本語  

    J-GLOBAL

    researchmap

  6. 降圧薬ヒドララジンは高脂肪食摂取した高血圧ラットの肝線維化を抑制する

    内藤久雄, 袁媛, 北森一哉, 橋本沙幸, 浅野友美, 八谷寛, 那須民江  

    日本衛生学雑誌(Web)75 巻 ( Supplement )   2020年

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    記述言語:日本語   掲載種別:会議報告等  

    J-GLOBAL

    researchmap

  7. 肥満に関連する疾病の増加と対策

    八谷 寛  

    日本医史学雑誌65 巻 ( 2 ) 頁: 172 - 172   2019年6月

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    記述言語:日本語   掲載種別:講演資料等(セミナー,チュートリアル,講習,講義他)   出版者・発行元:(一社)日本医史学会  

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  8. 日常的なライフスタイルを如何に論文化するか? 複合的な健康習慣の指標と循環器病予防

    八谷 寛, 玉腰 浩司  

    日本循環器病予防学会誌54 巻 ( 2 ) 頁: 106 - 106   2019年4月

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:講演資料等(セミナー,チュートリアル,講習,講義他)   出版者・発行元:(一社)日本循環器病予防学会  

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  9. 日本のがん患者の復職率 システマティックレビュー

    太田 充彦, 藤澤 明子, 河田 健司, 八谷 寛  

    日本衛生学雑誌74 巻 ( Suppl. ) 頁: S128 - S128   2019年2月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(一社)日本衛生学会  

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  10. 高血圧ラットは肝臓Cyp7a1 promoterメチル化頻度が高く、降圧剤投与で一部低下する

    内藤 久雄, 三宅 邦夫, 橋本 沙幸, 浅野 友美, 北森 一哉, 八谷 寛, 那須 民江  

    日本衛生学雑誌74 巻 ( Suppl. ) 頁: S177 - S177   2019年2月

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    記述言語:日本語   掲載種別:会議報告等   出版者・発行元:(一社)日本衛生学会  

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  11. 高血圧ラットは肝臓Cyp7a1 promoterメチル化頻度が高く、降圧剤投与で一部低下する

    内藤 久雄, 三宅 邦夫, 橋本 沙幸, 浅野 友美, 北森 一哉, 八谷 寛, 那須 民江  

    日本衛生学雑誌74 巻 ( Suppl. ) 頁: S177 - S177   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本衛生学会  

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  12. 新旧(1980-2020年)のライフスタイルからみた国民代表集団大規模コホート研究:NIPPON DATA80/90/2010/2020 食品摂取の多様性と尿中Na,K排泄量,血圧との関連:NIPPON DATA2010

    大塚礼, 八谷寛, 西信雄, 奥田奈賀子, 門田文, 由田克士, 大久保孝義, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    新旧(1980-2020年)のライフスタイルからみた国民代表集団大規模コホート研究:NIPPON DATA80/90/2010/2020 平成30年度 総括・分担研究報告書(Web)   2019年

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    記述言語:日本語   掲載種別:会議報告等  

    J-GLOBAL

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  13. 食品摂取の多様性と尿中Na,K排泄量、血圧との関連 NIPPON DATA2010

    大塚 礼, 八谷 寛, 西 信雄, 奥田 奈賀子, 門田 文, 由田 克士, 大久保 孝義, 岡村 智教, 上島 弘嗣, 岡山 明, 三浦 克之  

    日本公衆衛生学会総会抄録集77回 巻   頁: 322 - 322   2018年10月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:日本公衆衛生学会  

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  14. γGTPとALT追加による10年間の2型糖尿病発症リスク予測能の改善 愛知職域コホート 国際誌

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 豊嶋 英明, 青山 温子  

    日本公衆衛生学会総会抄録集77回 巻   頁: 204 - 204   2018年10月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:日本公衆衛生学会  

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  15. 健診と健康(地域健診、特定健診、職場健診は日本人の健康に寄与しているか?) 職域における若年期からの肥満対策と循環器病予防 招待有り

    八谷 寛, 李 媛英, 平川 仁尚, 太田 充彦, 上村 真由, 江 啓発, 金子 佳世, 豊嶋 英明, 玉腰 浩司, 青山 温子  

    日本循環器病予防学会誌53 巻 ( 2 ) 頁: 166 - 166   2018年5月

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:会議報告等   出版者・発行元:(一社)日本循環器病予防学会  

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  16. 成人男性におけるGGTとALTの組み合わせと2型糖尿病発症の関連 愛知職域コホート研究

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 青山 温子  

    日本循環器病予防学会誌53 巻 ( 2 ) 頁: 182 - 182   2018年5月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(一社)日本循環器病予防学会  

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  17. 健診と健康(地域健診、特定健診、職場健診は日本人の健康に寄与しているか?) 職域における若年期からの肥満対策と循環器病予防

    八谷 寛, 李 媛英, 平川 仁尚, 太田 充彦, 上村 真由, 江 啓発, 金子 佳世, 豊嶋 英明, 玉腰 浩司, 青山 温子  

    日本循環器病予防学会誌53 巻 ( 2 ) 頁: 166 - 166   2018年5月

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    記述言語:日本語   出版者・発行元:(一社)日本循環器病予防学会  

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  18. 成人男性におけるGGTとALTの組み合わせと2型糖尿病発症の関連 愛知職域コホート研究

    金子 佳世, 八谷 寛, 李 媛英, 上村 真由, 江 啓発, 平川 仁尚, 太田 充彦, 玉腰 浩司, 青山 温子  

    日本循環器病予防学会誌53 巻 ( 2 ) 頁: 182 - 182   2018年5月

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    記述言語:日本語   掲載種別:会議報告等   出版者・発行元:(一社)日本循環器病予防学会  

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  19. IoT(Internet of Things)システムの糖尿病療養指導への応用

    小林 朋子, 後藤 資実, 尾上 剛史, 村本 あき子, 加藤 綾子, 栄口 由香里, 野村 恵里, 武藤 繁貴, 八谷 寛, 津下 一代, 有馬 寛  

    糖尿病61 巻 ( Suppl.1 ) 頁: S - 440   2018年4月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(一社)日本糖尿病学会  

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  20. DPCデータを用いた脳卒中・急性心筋梗塞発症把握の可能性の検討

    柿崎 真沙子, 澤田 典絵, 山岸 良匡, 八谷 寛, 斉藤 功, 小久保 喜弘, 磯 博康, 津金 昌一郎, 康永 秀生  

    日本公衆衛生雑誌65 巻 ( 4 ) 頁: 179 - 186   2018年4月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

    目的 DPCデータを大規模なコホート研究の発症登録に利用することが可能であるかを検討するため、独自に収集した脳卒中および急性心筋梗塞発症登録数と、DPCデータを活用して得られた疾病登録数との比較を行い、脳卒中と急性心筋梗塞の各診断名において実施された治療・処置や検査から、標的疾患罹患の把握に有用な項目があるか検討した。方法 研究対象病院のDPCデータから、4種類(主傷病名、入院の契機となった病名、医療資源を最も投入した病名、医療資源を二番目に投入した病名)のいずれかに、急性心筋梗塞、脳内出血、脳梗塞が含まれる症例を抽出し、疾患ごとに実施された検査や治療の情報を抽出・集計し当該研究対象病院にてJPHC研究の一部として独自に収集した発症登録により得られた登録数を比較した。結果 DPLデータで抽出された症例数は独自に実施した発症登録数より多かったが、その差はとくに脳梗塞において顕著であった。JPHC登録数/DPC症例数の比は心筋梗塞1.13、脳内出血0.88、脳梗塞0.67であった。結論 急性心筋梗塞および脳内出血の疾病登録にはDPCデータを利用して、対象者数を概ね把握できる可能性が示された。脳梗塞についてはDPC登録病名とDPC治療・検査・診断項目を補助的に活用することで、疾病登録対象者数の同定精度を高め得る可能性がある。しかしながら、DPCデータを大規模なコホート研究の発症登録に利用するためには、地域全体での発症数がDPC導入病院の発症数でカバーできるのか、さらなる検討が必要である。(著者抄録)

    DOI: 10.11236/jph.65.4_179

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2018&ichushi_jid=J01074&link_issn=&doc_id=20180511440004&doc_link_id=130006731380&url=http%3A%2F%2Fci.nii.ac.jp%2Fnaid%2F130006731380&type=CiNii&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00003_1.gif

  21. トリクロロエチレンによる過敏症症候群における曝露濃度と感受性因子の交互作用 国際共著

    那須 民江, 王 海蘭, 伊藤 由起, 内藤 久雄, 柳場 由絵, 八谷 寛, 上島 通浩  

    日本衛生学雑誌73 巻 ( Suppl. ) 頁: S276 - S276   2018年3月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(一社)日本衛生学会  

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  22. 高血圧及び高脂肪食摂取はラット肝臓Cyp7a1プロモーターのメチル化頻度を増加させる

    内藤 久雄, 三宅 邦夫, 袁 媛, 橋本 沙幸, 北森 一哉, 八谷 寛, 那須 民江  

    日本衛生学雑誌73 巻 ( Suppl. ) 頁: S230 - S230   2018年3月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(一社)日本衛生学会  

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  23. 警察官採用に関わる色彩識別能力評価基準について

    高柳 泰世, 八谷 寛, 宮尾 克, 太田 充彦  

    産業衛生学雑誌60 巻 ( 2 ) 頁: 55 - 55   2018年3月

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    記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(公社)日本産業衛生学会  

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  24. 某労働基準監督署管内2事業場(製造業)における「治療と職業生活の両立支援のためのガイドライン」の周知状況について

    加藤 善士, 太田 充彦, 八谷 寛  

    産業衛生学雑誌60 巻 ( 2 ) 頁: 55 - 55   2018年3月

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    担当区分:最終著者   記述言語:日本語   掲載種別:研究発表ペーパー・要旨(全国大会,その他学術会議)   出版者・発行元:(公社)日本産業衛生学会  

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  25. 警察官採用に関わる色彩識別能力評価基準について

    高柳 泰世, 八谷 寛, 宮尾 克, 太田 充彦  

    産業衛生学雑誌60 巻 ( 2 ) 頁: 55 - 55   2018年3月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  26. 某労働基準監督署管内2事業場(製造業)における「治療と職業生活の両立支援のためのガイドライン」の周知状況について

    加藤 善士, 太田 充彦, 八谷 寛  

    産業衛生学雑誌60 巻 ( 2 ) 頁: 55 - 55   2018年3月

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    記述言語:日本語   出版者・発行元:(公社)日本産業衛生学会  

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  27. トリクロロエチレンによる過敏症症候群における曝露濃度と感受性因子の交互作用

    那須 民江, 王 海蘭, 伊藤 由起, 内藤 久雄, 柳場 由絵, 八谷 寛, 上島 通浩  

    日本衛生学雑誌73 巻 ( Suppl. ) 頁: S276 - S276   2018年3月

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    記述言語:日本語   出版者・発行元:(一社)日本衛生学会  

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  28. 高血圧及び高脂肪食摂取はラット肝臓Cyp7a1プロモーターのメチル化頻度を増加させる

    内藤 久雄, 三宅 邦夫, 袁 媛, 橋本 沙幸, 北森 一哉, 八谷 寛, 那須 民江  

    日本衛生学雑誌73 巻 ( Suppl. ) 頁: S230 - S230   2018年3月

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    記述言語:日本語   掲載種別:会議報告等   出版者・発行元:(一社)日本衛生学会  

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  29. 自宅から鉄道駅,バス停,職場までの距離と歩行時間との関連―愛知職域コホート

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    日本疫学会学術総会講演集(Web)28th 巻   頁: 129 (WEB ONLY)   2018年2月

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    記述言語:日本語  

    J-GLOBAL

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  30. 日本人一般住民における教育歴・経済状態と炎症マーカーの関連:NIPPON DATA2010

    村上慶子, 大久保孝義, 渡邉至, 二宮利治, 大西浩文, 八谷寛, 高嶋直敬, 宮川尚子, 門田文, 奥田奈賀子, 西信雄, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    日本疫学会学術総会講演集(Web)28th 巻   頁: 114 (WEB ONLY)   2018年2月

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    記述言語:日本語  

    J-GLOBAL

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  31. 料理ベース食事調査Webシステムのコホートでの活用に関するパイロット研究~第1報 実施方法と回答状況~

    藤田みほ, 石原淳子, 八谷寛, 八谷寛, 田中純太, 西本侑加, 丸谷幸子, 平川仁尚, 江啓発, 加藤祐子, 澤田典絵, 井上真奈美, 青山温子, 高地リベカ  

    日本疫学会学術総会講演集(Web)28th 巻   頁: 103 (WEB ONLY)   2018年2月

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    記述言語:日本語  

    J-GLOBAL

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  32. 料理データベース食事調査Webシステムのコホートでの活用に関するパイロット研究~第2報 摂取量の推定結果~

    加藤祐子, 石原淳子, 八谷寛, 八谷寛, 田中純太, 藤田みほ, 西本侑加, 丸谷幸子, 青山温子, 平川仁尚, 江啓発, 澤田典絵, 井上真奈美, 高地リベカ  

    日本疫学会学術総会講演集(Web)28th 巻   頁: 104 (WEB ONLY)   2018年2月

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    記述言語:日本語  

    J-GLOBAL

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  33. 食品摂取の多様性と心血管危険因子に関する検討:NIPPON DATA2010

    大塚礼, 大塚礼, 八谷寛, 西信雄, 奥田奈賀子, 門田文, 由田克士, 大久保孝義, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    日本疫学会学術総会講演集(Web)28th 巻   頁: 116 (WEB ONLY)   2018年2月

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    記述言語:日本語  

    J-GLOBAL

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  34. Pilot peer health education for noncommunicable disease prevention in Bangladesh, Ethiopia, and Palau

    Lemlem W Gebremariam, Yoshihisa Hirakawa, Shahrin E Rayna, Fahmida A Khan, Chifa Chiang, Yupeng He, Everlynn J Temengil, Sherilynn Madraisau, Md Khalequzzaman, Sohel R Choudhury, Hiroshi Yatsuya, Atsuko Aoyama  

    Journal of global health report2 巻   頁: e2018039   2018年

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)  

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  35. 社会的要因を含む生活習慣病リスク要因の解明を目指した国民代表集団の大規模コホート研究:NIPPON DATA80/90/2010 食品摂取の多様性と心血管危険因子に関する検討:NIPPON DATA2010

    大塚礼, 八谷寛, 西信雄, 奥田奈賀子, 門田文, 由田克士, 大久保孝義, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    社会的要因を含む生活習慣病リスク要因の解明を目指した国民代表集団の大規模コホート研究:NIPPON DATA80/90/2010 平成29年度 総括・分担研究報告書(Web)   頁: 91‐94 (WEB ONLY)   2018年

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    記述言語:日本語  

    J-GLOBAL

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  36. わが国の循環器疾患の危険因子「冠動脈疾患」

    松永 眞章, 八谷 寛  

    日本循環器病予防学会誌52 巻 ( 3 ) 頁: 244 - 254   2017年12月

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    記述言語:日本語   出版者・発行元:(一社)日本循環器病予防学会  

    国際的には低い冠動脈疾患発症率を誇るわが国ではあるが、肥満や不活発な生活習慣の蔓延による耐機能異常、脂質異常の割合の増加により、男性、特に都市部男性における発症率の増加が示唆されている。わが国における冠動脈疾患の危険因子(高血圧、脂質異常症、糖尿病、喫煙、肥満、メタボリックシンドローム、慢性腎臓病、飲酒)について、定義、冠動脈疾患発症、死亡との関連の特徴などについて個々に概説した。

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  37. 家庭での受動喫煙とその後のCOPDによる死亡との関連 JACC Study

    鵜川 重和, 玉腰 暁子, 八谷 寛, 山岸 良匡, 安藤 昌彦, 磯 博康  

    北海道公衆衛生学雑誌31 巻 ( 1特別付録 ) 頁: 90 - 90   2017年11月

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    記述言語:日本語   出版者・発行元:北海道公衆衛生学会  

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  38. 家庭での受動喫煙とその後のCOPDによる死亡との関連 JACC Study

    鵜川 重和, 玉腰 暁子, 八谷 寛, 山岸 良匡, 安藤 昌彦, 磯 博康  

    北海道公衆衛生学雑誌31 巻 ( 1特別付録 ) 頁: 90 - 90   2017年11月

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    記述言語:日本語   出版者・発行元:北海道公衆衛生学会  

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  39. Internet of Things(IoT)を活用した生活習慣改善支援の取り組み

    野村 恵里, 栄口 由香里, 加藤 綾子, 村本 あき子, 武藤 繁貴, 八谷 寛, 津下 一代  

    日本公衆衛生学会総会抄録集76回 巻   頁: 454 - 454   2017年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  40. パラオにおける食行動(果物・野菜摂取及び外食の頻度)と肥満との関連

    大内 詩野, 崔 仁哲, 本庄 かおり, 江 啓発, 八谷 寛, 青山 温子, 磯 博康  

    日本公衆衛生学会総会抄録集76回 巻   頁: 411 - 411   2017年10月

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    記述言語:日本語   出版者・発行元:日本公衆衛生学会  

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  41. パラオ共和国の若年者における飲酒と薬物使用の現状

    佐田 みずき, 崔 仁哲, 江 啓発, 八谷 寛, 本庄 かおり, 三田 貴, 磯 博康, 青山 温子  

    日本アルコール・薬物医学会雑誌52 巻 ( 4 ) 頁: 211 - 211   2017年8月

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    記述言語:日本語   出版者・発行元:(一社)日本アルコール・アディクション医学会  

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  42. 某労働基準監督署管内事業場における治療と職業生活の両立支援のための職場環境・労務管理制度

    加藤 善士, 太田 充彦, 八谷 寛  

    東海公衆衛生雑誌5 巻 ( 1 ) 頁: 102 - 110   2017年7月

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    記述言語:日本語   出版者・発行元:東海公衆衛生学会  

    目的 「事業場における治療と職業生活の両立支援のためのガイドライン(両立支援ガイドライン)」の認知、両立支援のための職場環境・労務管理体制の整備の実態、それらと事業場規模、事業場内産業保健スタッフ、過去の私傷病退職者・がん罹患者の有無との関連の探索。方法 某労働基準監督署管内の1,002事業場を対象に自記式質問紙調査を実施した。両立支援ガイドラインの認知割合、両立支援のための職場環境として啓発研修、相談・申出窓口、事業場内外の関係者間の情報交換の枠組みの有無、および、私傷病時に利用可能な労務管理制度として時差出勤、所定労働時間の短縮、時間単位の休暇、試し出勤、傷病・病気休暇の有無を調べ、事業場の規模による違いをコクラン・アーミテージ検定にて検定した。それらと事業場内産業保健スタッフ、および過去3年間に私傷病で退職した従業員・がんに罹患した従業員の有無との関連を調べ、Fisher正確確率検定で検定した。結果 266事業場から回答があり、回答率は27%であった。両立支援ガイドライン認知の割合は19%で、その割合は事業場規模が大きいほど高かった。啓発研修は7%、相談・申出窓口は38%、情報交換の枠組みは33%の事業場で行われており、事業場規模が大きいほどこの割合が高かった。従業員数50人未満の小規模事業場においては、事業場内産業保健スタッフのいる事業場で啓発研修(20%)、相談・申出窓口(52%)、情報交換の枠組み(48%)の実施割合が産業保健スタッフのいない事業場よりも高かった。両立支援のための各種労務管理制度の導入割合は1〜3割で、時間単位の休暇および傷病休暇・病気休暇は、事業場規模が大きいほど導入割合が高かった。過去3年間に私傷病で退職した従業員・がんに罹患した従業員の有無と両立支援のための職場環境・労務管理制度の有意な関連はなかった。ガイドラインを認知していた事業場では、従業員数50〜299人の中規模事業場では所定労働時間の短縮がより多く実施されていた。結論 両立支援ガイドライン認知の割合は低く、さらなる周知が望ましい。両立支援のための職場環境・労務管理制度の導入割合は一部先行研究よりも高く、事業場規模、産業保健スタッフの有無による違いを認めた。(著者抄録)

    DOI: 10.24802/tpha.5.1_102

    CiNii Books

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2017&ichushi_jid=J06245&link_issn=&doc_id=20170711480055&doc_link_id=%2Ffe4tokai%2F2017%2Fs00501%2F007%2F0102-0110%26dl%3D0&url=http%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Ffe4tokai%2F2017%2Fs00501%2F007%2F0102-0110%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

  43. IoT(Internet of Things)システムを用いた療養指導強化による糖代謝改善についての検討 教育入院患者を対象とした前向き研究

    小林 朋子, 後藤 資実, 尾上 剛史, 村本 あき子, 加藤 綾子, 栄口 由香里, 野村 恵里, 武藤 繁貴, 八谷 寛, 津下 一代, 有馬 寛  

    糖尿病60 巻 ( Suppl.1 ) 頁: S - 376   2017年4月

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    記述言語:日本語   出版者・発行元:(一社)日本糖尿病学会  

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  44. 宿泊型新保健指導プログラム(第2報) 1年後の効果検証

    松下 まどか, 矢部 大介, 小熊 祐子, 佐野 喜子, 樺山 舞, 八谷 寛, 荒川 雅志, 村本 あき子, 津下 一代  

    糖尿病60 巻 ( Suppl.1 ) 頁: S - 245   2017年4月

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    記述言語:日本語   出版者・発行元:(一社)日本糖尿病学会  

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  45. 【産業ストレスのバイオロジー:生物学的指標の現在と展望】職業性心理社会的要因と視床下部-下垂体-副腎皮質系ホルモンの関連

    太田 充彦, 八谷 寛  

    産業ストレス研究24 巻 ( 2 ) 頁: 205 - 211   2017年4月

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    記述言語:日本語   出版者・発行元:日本産業ストレス学会  

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  46. 解毒酵素の発現抑制が食餌性由来肝線維化進展に重要である

    内藤 久雄, 賈 小芳, 北森 一哉, 袁 媛, 八谷 寛, 那須 民江  

    日本衛生学雑誌72 巻 ( Suppl. ) 頁: S218 - S218   2017年3月

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    記述言語:日本語   出版者・発行元:(一社)日本衛生学会  

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  47. A Point-based Prediction Model for Predicting 10-year Risk of Developing Type 2 Diabetes Mellitus in Japanese Men: Aichi Workers' Cohort Study

    Yuanying Li, Hiroshi Yatsuya, Yoshihisa Hirakawa, Atsuhiko Ota, Masaaki Matsunaga, Hilawe Esayas Haregot, Chifa Chiang, Yan Zhang, Koji Tamakoshi, Hideaki Toyoshima, Atsuko Aoyama  

    CIRCULATION135 巻   2017年3月

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    記述言語:英語   掲載種別:研究発表ペーパー・要旨(国際会議)   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

    Web of Science

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  48. 社会的要因と食品摂取の多様性に関する検討:NIPPON DATA2010

    大塚礼, 大塚礼, 八谷寛, 西信雄, 奥田奈賀子, 尾島俊之, 中村美詠子, 由田克士, 藤吉朗, 門田文, 大久保孝義, 近藤慶子, 宮川尚子, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    日本疫学会学術総会講演集(Web)27th 巻   頁: 141 (WEB ONLY)   2017年1月

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    記述言語:日本語  

    J-GLOBAL

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  49. 地理的剥奪・ソーシャルキャピタルと主観的健康感の関連―愛知職域コホート

    村田千代栄, 八谷寛, 八谷寛, 埴淵知哉, 李媛英, 大塚礼, 豊嶋英明, 平川仁尚, 太田充彦, 加藤善士, 藤澤明子, 松永眞章, 江啓発, 玉腰浩司, 青山温子  

    日本疫学会学術総会講演集(Web)27th 巻   頁: 116 (WEB ONLY)   2017年1月

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    記述言語:日本語  

    J-GLOBAL

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  50. GISにより評価した自宅近隣のwalkabilityと散歩・早歩き習慣との関連―愛知職域コホート

    李媛英, 八谷寛, 八谷寛, 埴淵知哉, 平川仁尚, 太田充彦, 加藤善士, 藤澤明子, 松永眞章, 大塚礼, 村田千代栄, 江啓発, 玉腰浩司, 豊嶋英明, 青山温子  

    日本疫学会学術総会講演集(Web)27th 巻   頁: 109 (WEB ONLY)   2017年1月

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    記述言語:日本語  

    J-GLOBAL

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  51. 社会的要因を含む生活習慣病リスク要因の解明を目指した国民代表集団の大規模コホート研究:NIPPON DATA80/90/2010 社会的要因と食品摂取の多様性に関する検討:NIPPON DATA2010

    大塚礼, 八谷寛, 西信雄, 奥田奈賀子, 尾島俊之, 中村美詠子, 由田克士, 藤吉朗, 門田文, 大久保孝義, 近藤慶子, 宮川尚子, 岡村智教, 上島弘嗣, 岡山明, 三浦克之  

    社会的要因を含む生活習慣病リスク要因の解明を目指した国民代表集団の大規模コホート研究:NIPPON DATA80/90/2010 平成28年度 総括・分担研究報告書(Web)   頁: 80‐84 (WEB ONLY)   2017年

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    記述言語:日本語  

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▼全件表示

講演・口頭発表等 92

  1. 第一次緊急事態宣言下における大学生の日常行動とメンタルヘルスとの関係

    橋本幸之助、江啓発、八谷寛、HE Yupeng、平野有希子、平川仁尚、太田充彦、若泉謙太、島津明人、田淵貴大

    第39回日本国際保健医療学会西日本地方会  2021年3月6日 

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    開催年月日: 2021年3月

    記述言語:日本語   会議種別:ポスター発表  

  2. 職域における糖尿病の病態:発症予防・治療管理・予後 招待有り

    八谷寛

    第55回糖尿病学の進歩  2021年3月5日  日本糖尿病学会

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    開催年月日: 2021年3月

    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

    開催地:札幌  

  3. Automated Web-based Assessment system using Recipe-Data for Japanese (AWARDJP) – a pilot study for the middle and old age population-base cohort studies in Japan 国際会議

    Ribeka Takachi, Junko Ishihara, Sachiko Maruya, Junta Tanaka, Hiroshi Yatsuya, Atsuko Aoyama, Yoshihisa Hirakawa, Chifa Chiang, Tsuneo Konta, Takamasa Kayama, Manami Inoue, Norie Sawada, Shoichiro Tsugane

    eICDAM (International Conference on Diet and Activity Methods) 2021  2021年2月8日 

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    開催年月日: 2021年2月

    記述言語:英語   会議種別:ポスター発表  

    開催地:Ede   国名:オランダ王国  

  4. Comparison of artificial neural network and logistic regression for predicting common metabolic outcomes

    Yupeng HE, Chifa CHIANG, Yoshihisa HIRAKAWA, Hiroshi YATSUYA

    第31回日本疫学会学術総会  2021年1月27日 

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    開催年月日: 2021年1月

    記述言語:英語   会議種別:口頭発表(一般)  

  5. 職域男性就労者における現喫煙者の禁煙指導・意識と過去喫煙者の禁煙理由について(職域におけるアンケート調査から)

    加藤善士、太田充彦、八谷寛

    第66回東海公衆衛生学会  2020年7月11日 

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    開催年月日: 2020年7月

    記述言語:日本語   会議種別:口頭発表(一般)  

  6. 肥満度と心筋梗塞、脳卒中発症の関連---JALS研究シンポジウム 日本の心臓血管疾患の疫学研究:大規模コホート統合研究(JALS)

    八谷 寛

    第58回日本心臓病学会学術集会 

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    開催年月日: 2010年9月

    記述言語:日本語   会議種別:口頭発表(招待・特別)  

    国名:日本国  

  7. Conventional Risk Factors for Heart Failure Mortality: The JACC Study 国際会議

    50th Cardiovascular Disease Epidemiology and Prevention Annual Conference (American Heart Association) 

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    開催年月日: 2010年3月

    記述言語:英語   会議種別:ポスター発表  

  8. Race and Sex-Specific Associations of Obesity Measures with Ischemic Stroke Incidencein the ARIC Study 国際会議

    50th Cardiovascular Disease Epidemiology and Prevention Annual Conference (American Heart Association) 

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    開催年月日: 2010年3月

    記述言語:英語   会議種別:ポスター発表  

  9. Independent association of serum adiponectin and alanine amino transferase with the incidence of diabetes mellitus in middle-aged Japanese men: 5-year follow-up 国際会議

    Li Y, Yatsuya H, Toyoshima H, Iso H, Tamakoshi K.

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    開催年月日: 2010年1月

    記述言語:英語  

    国名:日本国  

  10. 職域集団から学ぶ肥満の成因と健康影響 産業保健課題としての肥満の成因・病態と予防

    豊嶋英明、八谷 寛、近藤良伸、玉腰浩司

    平成21年度日本産業衛生学会東海地方会学会シンポジウム 

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    開催年月日: 2009年11月

    記述言語:日本語   会議種別:口頭発表(招待・特別)  

    国名:日本国  

  11. Body mass index and mortality among Japanese older adults: Findings from the JACC Study 国際会議

    Obesity 2009―27th Annual Scientific Meeting of the Obesity Society 

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    開催年月日: 2009年10月

    記述言語:英語   会議種別:口頭発表(一般)  

  12. 生活習慣とメタボリックシンドローム発症リスクに関する追跡研究

    李媛英、八谷寛、豊嶋英明、玉腰浩司

    第68回日本公衆衛生学会総会 

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    開催年月日: 2009年10月

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  13. 勤労男性における「食事バランスガイド」を参考にした食生活の実現可能性と課題

    嶋田雅子、武見ゆかり、大久保公美、村上健太郎、大塚礼、八谷寛、佐々木敏

    第56回日本栄養改善学会学術総会 

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    開催年月日: 2009年9月

    記述言語:日本語  

    国名:日本国  

  14. 体格と身体活動の乳がんに対するリスク-JACC Studyの知見より.

    鈴木貞夫,小嶋雅代,徳留信寛,森満,坂内文男,藤野善久,若井建志,玉腰浩司,八谷寛,林櫻松,菊地正悟,玉腰暁子.

    第10回日本がん分子疫学研究会 第16回日本がん予防学会 第32回日本がん疫学研究会 

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    開催年月日: 2009年6月

    記述言語:日本語  

    国名:日本国  

  15. Body Mass Index and Risk of Stroke in Japanese Men and Women: A Meta-analysis of 16 Cohorts in Japan 国際会議

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    開催年月日: 2009年3月

    記述言語:英語   会議種別:ポスター発表  

  16. 高齢者のBMIと総死亡リスク:JACCStudyから

    玉腰暁子, 林櫻松, 柳生聖子, 菊地正悟, 鈴木貞夫, 玉腰浩司, 近藤高明, 八谷寛

    第19回日本疫学会学術総会. 

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    開催年月日: 2009年1月

    記述言語:日本語  

    国名:日本国  

  17. Lifestyle and incidence of metabolic syndrome: a follow-up study 国際会議

    The Obesity Society's 2007 Annual Scientific Meeting 

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    開催年月日: 2007年10月

    記述言語:英語   会議種別:口頭発表(一般)  

    Background
    Metabolic syndrome (MS) is a high risk state for the development of cardiovascular diseases and diabetes. In this study, adherence to healthy lifestyles were examined for their composite effect on the incidence of MS in Japan.
    Methods
    Men who did not have two or more MS components nor past medical history of cancer, cardiovascular diseases, diabetes, hypertension, and hyperlipidemia were followed for three years to the incidence of MS (n=1,688, mean age: 46.2 years old, mean body m

  18. Eating fast leads to obesity: Findings in Japanese non-diabetic men and women. 国際会議

    The North American Association of Study of Obesity 2005 Annual Scientific Meeting 

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    開催年月日: 2005年11月

    記述言語:英語   会議種別:ポスター発表  

  19. Hypoadiponectinemia adds further inflamatory information to ordinary metabolic syndrome components. 国際会議

    European Society of Cardiology Congress (Stockholm, Sweden) 

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    開催年月日: 2005年10月

    記述言語:英語   会議種別:口頭発表(一般)  

  20. Association between birth weight and white blood cell count in adulthood. 国際会議

    The XVII International scientific meeting of the international epidemiological association (Bangkok, Thailand) 

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    開催年月日: 2005年8月

    記述言語:英語   会議種別:ポスター発表  

  21. Factors associated with insomnia among male civil servants in Japan. 国際会議

    The XVII International scientific meeting of the international epidemiological association (Bangkok, Thailand) 

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    開催年月日: 2005年8月

    記述言語:英語   会議種別:ポスター発表  

  22. 心理的要因と乳がんリスクとの関連-大規模コホートによる検討-

    若井建志, 小嶋雅代, 八谷寛, 他10人(4番目).

    第15回日本疫学会( 大津) 

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    開催年月日: 2005年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  23. 極めて健康な成人男性におけるadiponectinとC反応性蛋白の関連

    松下邦洋、八谷寛、玉腰浩司、他

    第40回日本循環器病予防学会(横浜) 

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    開催年月日: 2005年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  24. 生活習慣病の家族歴と罹患集積状況との関連

    和田恵子、玉腰浩司、八谷寛、他.

    第40回日本循環器病予防学会(横浜) 

     詳細を見る

    開催年月日: 2005年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  25. 食べる速さと現在のBMI、20歳からのBMI変化量との関連

    大塚礼、玉腰浩司、八谷寛、他.

    第40回日本循環器病予防学会(横浜) 

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    開催年月日: 2005年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  26. Simultaneous deterioration of several cardiovascular disease predictors in apparently healthy Japanese Men with metabolic syndrome.

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    開催年月日: 2005年

    記述言語:英語   会議種別:ポスター発表  

    国名:日本国  

  27. 縦断的検討による「腹いっぱい食べる」習慣の推移と5年間のBMI変化量との関係.

    大塚礼、八谷寛、玉腰浩司、他5人(2番目).

    第15回日本疫学会(大津) 

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    開催年月日: 2005年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  28. 日本の事務職男性公務員における不眠と職業ストレスとの関連.

    村田千代栄、八谷寛、玉腰浩司、他4人(2番目).

    第15回日本疫学会(大津) 

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    開催年月日: 2005年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  29. 同一個人の追跡観察からえた経年的血圧測定値の多重レベル解析-階層構造データへの適用の利点-

    近藤高明, 渡邊ゆかり, 八谷寛, 他3人(4番目).

    第15回日本疫学会( 大津) 

     詳細を見る

    開催年月日: 2005年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  30. Life Space and Mortality among the Functionally Independent Elderly. 国際会議

    132nd Annual Meeting of The American Public Health Association (Washington DC, USA) 

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    開催年月日: 2004年11月

    記述言語:英語   会議種別:口頭発表(一般)  

  31. Perceived Mental Stress and Serum Leptin Concentration in Japanese Male Workers 国際会議

    The North American Association of Study of Obesity 2004 Annual Scientific Meeting (Las Vegas, USA) 

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    開催年月日: 2004年11月

    記述言語:英語   会議種別:ポスター発表  

  32. Characteristics of Community Dwelling Homebound Elderly in Japan : Baseline Report. 国際会議

    132nd Annual Meeting of The American Public Health Association (Washington DC, USA) 

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    開催年月日: 2004年11月

    記述言語:英語   会議種別:口頭発表(一般)  

  33. 7年間の追跡研究による地域在住高齢者の日常活動度と生命予後の関連について

    村田千代栄、近藤高明、八谷寛、他5人(6番目).

    愛知県公衆衛生研究会(大府) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  34. 大塚礼、八谷寛、玉腰浩司、他4人(2番目). 職域コホートにおける血清レプチン濃度と生活習慣との関連

    第39回日本循環器病予防学会(旭川) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  35. 濃い味の好みと肥満との関連性に関する検討

    堀容子、大塚礼、八谷寛、他4人(4番目).

    第39回日本循環器病予防学会(旭川) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  36. Power to detect prior myocardial infarction by ECG findings at health examination. 国際会議

    The 31st International Congress on Electrocardiology (Kyoto, Japan) 

     詳細を見る

    開催年月日: 2004年

    記述言語:英語   会議種別:口頭発表(一般)  

    国名:日本国  

  37. メタボリックシンドロームにおけるアディポネクチンの意義.

    八谷寛

    第1回名古屋循環器疫学研究会(名古屋) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(招待・特別)  

    国名:日本国  

  38. 飲酒と女性乳がん罹患リスクの関連.

    林櫻松, 菊地正悟, 八谷寛, 他9人(5番目).

    第63回日本癌学会( 福岡) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  39. 喫煙と卵巣癌罹患リスクの関連.

    丹羽慶光, 西尾和子, 八谷寛, 他7人(5番目).

    第63回日本癌学会( 福岡) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  40. 生殖歴と乳がん罹患リスクとの関連.

    玉腰浩司, 豊嶋英明, 八谷寛, 他7人(8番目).

    第63回日本癌学会( 福岡) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  41. 脂質摂取と乳がん罹患リスクとの関連 日本における大規模コホート研究による検討.

    若井建志, 玉腰浩司, 八谷寛, 他8人(3番目).

    第63回日本癌学会( 福岡) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  42. 大豆製品摂取と乳がん罹患リスクとの関連.

    西尾和子、玉腰浩司、八谷寛、他7人(3番目).

    第63回日本癌学会(福岡) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  43. アディポネクチンは肥満度、インスリン抵抗性とは独立にMetabolic Syndromeに関連する

    八谷寛、玉腰浩司、大塚礼、近藤高明、豊嶋英明.

    第25回日本肥満学会(大阪) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  44. 各種肥満指標をmetabolic syndrome関連兆候のスクリーニングに用いた場合の有用性

    近藤高明、堀容子、八谷寛、玉腰浩司、豊嶋英明.

    第25回日本肥満学会(大阪) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  45. 職域男性における自覚的ストレスと血清レプチン濃度との関連

    大塚礼、八谷寛、玉腰浩司、他4人(2番目).

    第25回日本肥満学会(大阪) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  46. 人口寄与危険度割合を用いた職域集団での高血圧危険要因の評価 オッズ比との比較

    近藤高明、八谷寛、玉腰浩司、岡村愛.

    第77回産業衛生学会(名古屋) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  47. Serum phospholipid transfer protein mass as a possible protective factor for coronary heart diseases.

     詳細を見る

    開催年月日: 2004年

    記述言語:英語   会議種別:ポスター発表  

    国名:日本国  

  48. 職域コホート研究における既往歴の妥当性(虚血性心疾患及び脳卒中)

    八谷寛、豊嶋英明、張恵明、他7人(1番目).

    第14回日本疫学会(山形) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  49. 長期の体重変動とMetabolic Syndromeとの関連

    張恵明、玉腰浩司、八谷寛、他8人(3番目).

    第14回日本疫学会(山形) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  50. 血清レプチン値と高血圧の関連

    和田恵子、八谷寛、間淵智子、他7人(2番目).

    第14回日本疫学会(山形) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  51. 自覚的ストレスと血清レプチン濃度との関連(男性における関連)

    大塚礼、八谷寛、玉腰浩司、他7人(2番目).

    第14回日本疫学会(山形) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  52. A nested case-control study of stomach cancer in relation to green tea consumption in Japan.

     詳細を見る

    開催年月日: 2004年

    記述言語:英語   会議種別:ポスター発表  

    国名:日本国  

  53. 前向き研究による血清Helicobacter pyloli、低pepsinogenと胃がんリスク.

    菊地正悟, 柳生聖子, 八谷寛, 他11人(5番目).

    第14回日本疫学会(山形) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  54. 職域集団における自己申告の身長、体重の妥当性

    和田恵子、玉腰浩司、八谷寛、他6人(8番目).

    第39回日本循環器病予防学会(旭川) 

     詳細を見る

    開催年月日: 2004年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  55. 健診時心電図による冠動脈閉塞の既往に対する判定精度について

    張恵明、八谷寛、玉腰浩司、近藤高明、豊嶋英明.

    第19回心電情報ワークショップ(小田原) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  56. 若年期からの体重変化、体重変動と血清レプチン濃度との関連

    八谷寛、玉腰浩司、吉田 勉、他3人(1番目).

    第24回日本肥満学会(千葉) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  57. 禁煙による食生活の変化と体重増加との関係

    八谷寛、太田尚寿、玉腰浩司、他8人(1番目).

    第38回日本循環器病予防学会(和歌山) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  58. 多変量解析を用いた高血圧と脳卒中のfamilial aggregationとcoaggregationの評価

    近藤高明、豊嶋英明、八谷寛、他4人(4番目).

    第38回日本循環器病予防学会(和歌山) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  59. 間淵智子、八谷寛、玉腰浩司、他6人(2番目). 愛知県職域コホートのベースラインデータ時におけるレプチンと白血球の関連

    第38回日本循環器病予防学会(和歌山) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  60. 日本人男性における体重変動と空腹時血清インスリン濃度との関連

    八谷寛、玉腰浩司、張 恵明、他8人(1番目).

    第13回日本疫学会(福岡) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  61. 体重変動と軽度C-reactive protein上昇との関連

    玉腰浩司、八谷寛、近藤高明、他8人(2番目).

    第13回日本疫学会(福岡) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  62. 扁平足における足裏の痛み・疲れ、および扁平足と肥満との関連性

    大塚礼、八谷寛、村田千代栄、他12人(2番目).

    第13回日本疫学会(福岡) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  63. 「濃い味付けの好み」と心血管リスクファクターとの関連性についての検討

    堀容子、豊嶋英明、近藤高明、玉腰浩司、八谷寛.

    第13回日本疫学会(福岡) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:ポスター発表  

    国名:日本国  

  64. 健診時心電図の判読における留意点の抽出.

    張恵明、八谷寛、玉腰浩司、他11人(2番目).

    第49回東海公衆衛生学会(浜松) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  65. 長野県阿南町での下肢からの高齢者健康づくり事業の評価-下肢機能と測定形態の変化からみた介入効果-

    近藤高明、堀容子、八谷寛、他7人(4番目).

    第14回日本老年医学会東海地方会(名古屋) 

     詳細を見る

    開催年月日: 2003年

    記述言語:日本語   会議種別:口頭発表(一般)  

    国名:日本国  

  66. Self rated health after medical care utilization. 国際会議

    131st Annual Meeting of The American Public Health Association (San Franscisco, USA) 

     詳細を見る

    開催年月日: 2003年

    記述言語:英語   会議種別:口頭発表(一般)  

  67. 甘粛省天水市奥地の衛生院と小学校の視察に基づいた中国辺境地の衛生と教育事情に関する一活動報告

    石川美由紀、近藤高明、八谷寛、他5人(4番目).

    第48回東海公衆衛生学会(津)