日本癌学会

日本遺伝子治療学会

日本術中画像情報学会   理事

Generation and measurement of low-temperature plasma for cancer therapy: a historical review

Ishikawa, K; Takeda, K; Yoshimura, S; Kondo, T; Tanaka, H; Toyokuni, S; Nakamura, K; Kajiyama, H; Mizuno, M; Hori, M

FREE RADICAL RESEARCH   57 巻 ( 3 ) 頁： 239 - 270   2023年3月

Cancer-specific cytotoxicity of Ringer's acetate solution irradiated by cold atmospheric pressure plasma

Miron, C; Ishikawa, K; Kashiwagura, S; Suda, Y; Tanaka, H; Nakamura, K; Kajiyama, H; Toyokuni, S; Mizuno, M; Hori, M

FREE RADICAL RESEARCH   57 巻 ( 2 ) 頁： 91 - 104   2023年2月

Cooperation of Poly(rC)-binding Proteins 1/2 and Glutathione in Ferroptosis Induced by Plasma-activated Ringer's Lactate

Zheng, H; Jiang, L; Lyu, QY; Akatsuka, S; Motooka, Y; Sekido, Y; Nakamura, K; Tanaka, H; Ishikawa, K; Kajiyama, H; Mizuno, M; Hori, M; Toyokuni, S

CANCER SCIENCE   114 巻   頁： 749 - 749   2023年2月

Cooperation of Poly(rC)-binding Proteins 1/2 and Glutathione in Ferroptosis Induced by Plasmaactivated Ringer's Lactate

Zheng, H; Jiang, L; Lyu, QY; Akatsuka, S; Motooka, Y; Sekido, Y; Nakamura, K; Tanaka, H; Ishikawa, K; Kajiyama, H; Mizuno, M; Hori, M; Toyokuni, S

CANCER SCIENCE   114 巻   頁： 1340 - 1340   2023年2月

Plasma activated Ringer's lactate solution

Tanaka, H; Mizuno, M; Ishikawa, K; Miron, C; Okazaki, Y; Toyokuni, S; Nakamura, K; Kajiyama, H; Hori, M

FREE RADICAL RESEARCH   57 巻 ( 1 ) 頁： 14 - 20   2023年1月

Influence of background characteristics in responders of regenerative therapy by periurethral injection of adipose-derived regenerative cells for male stress urinary incontinence

Yamanishi, T; Ishizuka, O; Shimizu, S; Kobayashi, Y; Kinoshita, F; Yamamoto, T; Mizokami, A; Narimoto, K; Toriyama, K; Kamei, Y; Kuwatsuka, Y; Mizuno, M; Gotoh, M

LUTS-LOWER URINARY TRACT SYMPTOMS   14 巻 ( 4 ) 頁： 273 - 280   2022年7月

Cytotoxicity of plasma-irradiated lactate solution produced under atmospheric airtight conditions and generation of the methyl amino group

Ito, D; Iwata, N; Ishikawa, K; Nakamura, K; Hashizume, H; Miron, C; Tanaka, H; Kajiyama, H; Toyokuni, S; Mizuno, M; Hori, M

APPLIED PHYSICS EXPRESS   15 巻 ( 5 )   2022年5月

Enhancement of ethanol production and cell growth in budding yeast by direct irradiation of low-temperature plasma

Tanaka Hiromasa, Matsumura Shogo, Ishikawa Kenji, Hashizume Hiroshi, Ito Masafumi, Nakamura Kae, Kajiyama Hiroaki, Kikkawa Fumitaka, Ito Mikako, Ohno Kinji, Okazaki Yasumasa, Toyokuni Shinya, Mizuno Masaaki, Hori Masaru

JAPANESE JOURNAL OF APPLIED PHYSICS   61 巻 ( SA )   2022年1月

Plasma-activated Ringer's lactate solution inhibits the cellular respiratory system in HeLa cells

Tanaka, H; Maeda, S; Nakamura, K; Hashizume, H; Ishikawa, K; Ito, M; Ohno, K; Mizuno, M; Motooka, Y; Okazaki, Y; Toyokuni, S; Kajiyama, H; Kikkawa, F; Hori, M

PLASMA PROCESSES AND POLYMERS   18 巻 ( 10 )   2021年10月

Low temperature plasma irradiation products of sodium lactate solution that induce cell death on U251SP glioblastoma cells were identified

Tanaka, H; Hosoi, Y; Ishikawa, K; Yoshitake, J; Shibata, T; Uchida, K; Hashizume, H; Mizuno, M; Okazaki, Y; Toyokuni, S; Nakamura, K; Kajiyama, H; Kikkawa, F; Hori, M

SCIENTIFIC REPORTS   11 巻 ( 1 ) 頁： 18488   2021年9月

Intravenously delivered multilineage-differentiating stress enduring cells dampen excessive glutamate metabolism and microglial activation in experimental perinatal hypoxic ischemic encephalopathy

Suzuki Toshihiko, Sato Yoshiaki, Kushida Yoshihiro, Tsuji Masahiro, Wakao Shohei, Ueda Kazuto, Imai Kenji, Iitani Yukako, Shimizu Shinobu, Hida Hideki, Temma Takashi, Saito Shigeyoshi, Iida Hidehiro, Mizuno Masaaki, Takahashi Yoshiyuki, Dezawa Mari, Borlongan Cesar V, Hayakawa Masahiro

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM   41 巻 ( 7 ) 頁： 1707 - 1720   2021年7月

Lysosomal nitric oxide determines transition from autophagy to ferroptosis after exposure to plasma-activated Ringer's lactate

Jiang, L; Zheng, H; Lyu, QY; Hayashi, S; Sato, K; Sekido, Y; Nakamura, K; Tanaka, H; Ishikawa, K; Kajiyama, H; Mizuno, M; Hori, M; Toyokuni, S

REDOX BIOLOGY   43 巻   頁： 101989   2021年7月

Preclinical Verification of the Efficacy and Safety of Aqueous Plasma for Ovarian Cancer Therapy

Nakamura, K; Yoshikawa, N; Mizuno, Y; Ito, M; Tanaka, H; Mizuno, M; Toyokuni, S; Hori, M; Kikkawa, F; Kajiyama, H

CANCERS   13 巻 ( 5 )   2021年3月

Improvement of yield and grain quality by periodic cold plasma treatment with rice plants in a paddy field 査読有り

Hashizume, H; Kitano, H; Mizuno, H; Abe, A; Yuasa, G; Tohno, S; Tanaka, H; Ishikawa, K; Matsumoto, S; Sakakibara, H; Nikawa, S; Maeshima, M; Mizuno, M; Hori, M

PLASMA PROCESSES AND POLYMERS   18 巻 ( 1 )   2021年1月

Biological characterization of adipose-derived regenerative cells used for the treatment of stress urinary incontinence

Okabe, YT; Shimizu, S; Suetake, Y; Matsui-Hirai, H; Hasegawa, S; Takanari, K; Toriyama, K; Kamei, Y; Yamamoto, T; Mizuno, M; Gotoh, M

INTERNATIONAL JOURNAL OF UROLOGY   28 巻 ( 1 ) 頁： 115 - 124   2021年1月

Cancer Treatments Using Low-Temperature Plasma

Tanaka, H; Mizuno, M; Ishikawa, K; Toyokuni, S; Kajiyama, H; Kikkawa, F; Hori, M

CURRENT MEDICINAL CHEMISTRY   28 巻 ( 41 ) 頁： 8549 - 8558   2021年

Regenerative treatment for male stress urinary incontinence by periurethral injection of adipose-derived regenerative cells: Outcome of the ADRESU study

Gotoh, M; Shimizu, S; Yamamoto, T; Ishizuka, O; Yamanishi, T; Mizokami, A; Narimoto, K; Toriyama, K; Kamei, Y; Nakayama, S; Kuwatsuka, Y; Mizuno, M; Hirakawa, A

INTERNATIONAL JOURNAL OF UROLOGY   27 巻 ( 10 ) 頁： 859 - 865   2020年10月

Adjusted multiple gases in the plasma flow induce differential antitumor potentials of plasma-activated solutions

Nakamura, K; Yoshikawa, N; Yoshihara, M; Ikeda, Y; Higashida, A; Niwa, A; Jindo, T; Tanaka, H; Ishikawa, K; Mizuno, M; Toyokuni, S; Hori, M; Kikkawa, F; Kajiyama, H

PLASMA PROCESSES AND POLYMERS   17 巻 ( 10 )   2020年10月

Non-thermal plasma-activated lactate solution kills U251SP glioblastoma cells in an innate reductive manner with altered metabolism

Ishikawa, K; Hosoi, Y; Tanaka, H; Jiang, L; Toyokuni, S; Nakamura, K; Kajiyama, H; Kikkawa, F; Mizuno, M; Hori, M

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   688 巻   頁： 108414   2020年7月

Plasma-activated medium promotes autophagic cell death along with alteration of the mTOR pathway

Yoshikawa, N; Liu, WT; Nakamura, K; Yoshida, K; Ikeda, Y; Tanaka, H; Mizuno, M; Toyokuni, S; Hori, M; Kikkawa, F; Kajiyama, H

SCIENTIFIC REPORTS   10 巻 ( 1 ) 頁： 1614   2020年1月

Oxidative stress-dependent and -independent death of glioblastoma cells induced by non-thermal plasma-exposed solutions

Tanaka, H; Mizuno, M; Katsumata, Y; Ishikawa, K; Kondo, H; Hashizume, H; Okazaki, Y; Toyokuni, S; Nakamura, K; Yoshikawa, N; Kajiyama, H; Kikkawa, F; Hori, M

SCIENTIFIC REPORTS   9 巻 ( 1 ) 頁： 13657   2019年9月

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy

Iida Madoka, Sahashi Kentaro, Kondo Naohide, Nakatsuji Hideaki, Tohnai Genki, Tsutsumi Yutaka, Noda Seiya, Murakami Ayuka, Onodera Kazunari, Okada Yohei, Nakatochi Masahiro, Okabe Yuka Tsukagoshi, Shimizu Shinobu, Mizuno Masaaki, Adachi Hiroaki, Okano Hideyuki, Sobue Gen, Katsuno Masahisa

NATURE COMMUNICATIONS   10 巻 ( 1 ) 頁： 4262   2019年9月

Non-thermal plasma specifically kills oral squamous cell carcinoma cells in a catalytic Fe(II)-dependent manner

Sato, K; Shi, L; Ito, F; Ohara, Y; Motooka, Y; Tanaka, H; Mizuno, M; Hori, M; Hirayama, T; Hibi, H; Toyokuni, S

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION   65 巻 ( 1 ) 頁： 8 - 15   2019年7月

Design of a Randomized Controlled Clinical Study of tissue-engineered osteogenic materials using bone marrow-derived mesenchymal cells for Maxillomandibular bone defects in Japan: the TEOM study protocol

Shimizu Shinobu, Tsuchiya Shuhei, Hirakawa Akihiro, Kato Katsuyoshi, Ando Masahiko, Mizuno Masaaki, Osugi Masashi, Okabe Kazuto, Katagiri Wataru, Hibi Hideharu

BMC ORAL HEALTH   19 巻   2019年4月

Development of novel diagnostic system for pancreatic cancer, including early stages, measuring mRNA of whole blood cells

Sakai Yoshio, Honda Masao, Matsui Shigeyuki, Komori Osamu, Murayama Toshinori, Fujiwara Tadami, Mizuno Masaaki, Imai Yasuhito, Yoshimura Kenichi, Nasti Alessandro, Wada Takashi, Iida Noriho, Kitahara Masaaki, Horii Rika, Toshikatsu Tamai, Nishikawa Masashi, Okafuji Hirofumi, Mizukoshi Eishiro, Yamashita Tatsuya, Yamashita Taro, Arai Kuniaki, Kitamura Kazuya, Kawaguchi Kazunori, Takatori Hajime, Shimakami Tetsuro, Terashima Takeshi, Hayashi Tomoyuki, Nio Kouki, Kaneko Shuichi

CANCER SCIENCE   110 巻 ( 4 ) 頁： 1364 - 1388   2019年4月

Impact of Therapeutic Angiogenesis Using Autologous Bone Marrow-Derived Mononuclear Cells Implantation in Critical Limb Ischemia With Scleroderma - Subanalysis of the Long-Term Clinical Outcomes Survey -

Shoji Keisuke, Yanishi Kenji, Yoshimi Ryusuke, Hamada Naoki, Kondo Kazuhisa, Fujimoto Kazuteru, Nakajima Hideaki, Kuwahara Koichiro, Higashi Yukihito, Fukumoto Yoshihiro, Murohara Toyoaki, Matoba Satoaki, Hayashida Ryo, Shibata Rei, Murotani Kenta, Ando Masahiko, Mizuno Masaaki, Fujiwara Tadami, Kato Tamon, Kajikawa Masato, Ootsuka Masanori, Sasaki Kenichiro, Saito Yoshihiko, Fukumoto Shinya

CIRCULATION JOURNAL   83 巻 ( 3 ) 頁： 662 - 671   2019年3月

Non-thermal plasma-activated medium modified metabolomic profiles in the glycolysis of U251SP glioblastoma

Kurake, N; Ishikawa, K; Tanaka, H; Hashizume, H; Nakamura, K; Kajiyama, H; Toyokuni, S; Kikkawa, F; Mizuno, M; Hori, M

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS   662 巻   頁： 83 - 92   2019年2月

Molecular mechanisms of non-thermal plasmainduced effects in cancer cells

Tanaka, H; Mizuno, M; Ishikawa, K; Toyokuni, S; Kajiyama, H; Kikkawa, F; Hori, M

BIOLOGICAL CHEMISTRY   400 巻 ( 1 ) 頁： 87 - 91   2019年1月

Supermolecular drug challenge to overcome drug resistance in cancer cells

Onishi, Y; Eshita, Y; Ji, RC; Kobayashi, T; Onishi, M; Mizuno, M; Yoshida, J; Kubota, N

DRUG DISCOVERY TODAY   23 巻 ( 8 ) 頁： 1556 - 1563   2018年8月

Long-Term Clinical Outcomes Survey of Bone Marrow-Derived Cell Therapy in Critical Limb Ischemia in Japan

Kondo, K; Yanishi, K; Hayashida, R; Shintani, S; Shibata, R; Murotani, K; Ando, M; Mizuno, M; Fujiwara, T; Murohara, T; Matoba, S

CIRCULATION JOURNAL   82 巻 ( 4 ) 頁： 1168 - 1178   2018年4月

Glioblastoma Cell Lines Display Different Sensitivities to Plasma-Activated Medium

Tanaka Hiromasa, Mizuno Masaaki, Ishikawa Kenji, Takeda Keigo, Hashizume Hiroshi, Nakamura Kae, Utsumi Fumi, Kajiyama Hiroaki, Okazaki Yasumasa, Toyokuni Shinya, Akiyama Shinichi, Maruyama Shoichi, Kikkawa Fumitaka, Hori Masaru

IEEE TRANSACTIONS ON RADIATION AND PLASMA MEDICAL SCIENCES   2 巻 ( 2 ) 頁： 99-102   2018年3月

Effect of Plasma-Activated Lactated Ringer's Solution on Pancreatic Cancer Cells In Vitro and In Vivo

Sato Yusuke, Yamada Suguru, Takeda Shigeomi, Hattori Norifumi, Nakamura Kae, Tanaka Hiromasa, Mizuno Masaaki, Hori Masaru, Kodera Yasuhiro

ANNALS OF SURGICAL ONCOLOGY   25 巻 ( 1 ) 頁： 299 - 307   2018年1月

Crystallization of calcium oxalate dihydrate in a buffered calcium-containing glucose solution by irradiation with non-equilibrium atmospheric pressure plasma

Kurake, N; Tanaka, H; Ishikawa, K; Nakamura, K; Kajiyama, H; Kikkawa, F; Mizuno, M; Ikehara, Y; Hori, M

JOURNAL OF APPLIED PHYSICS   122 巻 ( 14 )   2017年10月

Design of a single-arm clinical trial of regenerative therapy by periurethral injection of adipose-derived regenerative cells for male stress urinary incontinence in Japan: the ADRESU study protocol

Shimizu Shinobu, Yamamoto Tokunori, Nakayama Shinobu, Hirakawa Akihiro, Kuwatsuka Yachiyo, Funahashi Yasuhito, Matsukawa Yoshihisa, Takanari Keisuke, Toriyama Kazuhiro, Kamei Yuzuru, Narimoto Kazutaka, Yamanishi Tomonori, Ishizuka Osamu, Mizuno Masaaki, Gotoh Momokazu

BMC UROLOGY   17 巻 ( 1 ) 頁： 89   2017年9月

Novel Intraperitoneal Treatment With Non-Thermal Plasma-Activated Medium Inhibits Metastatic Potential of Ovarian Cancer Cells

Nakamura, K; Peng, Y; Utsumi, F; Tanaka, H; Mizuno, M; Toyokuni, S; Hori, M; Kikkawa, F; Kajiyama, H

SCIENTIFIC REPORTS   7 巻 ( 1 ) 頁： 6085   2017年7月

Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy

Shi, L; Ito, F; Wang, Y; Okazaki, Y; Tanaka, H; Mizuno, M; Hori, M; Hirayama, T; Nagasawa, H; Richardson, DR; Toyokuni, S

FREE RADICAL BIOLOGY AND MEDICINE   108 巻   頁： 904 - 917   2017年7月

Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer

Takeda Shigeomi, Yamada Suguru, Hattori Norifumi, Nakamura Kae, Tanaka Hiromasa, Kajiyama Hiroaki, Kanda Mitsuro, Kobayashi Daisuke, Tanaka Chie, Fujii Tsutomu, Fujiwara Michitaka, Mizuno Masaaki, Hori Masaru, Kodera Yasuhiro

ANNALS OF SURGICAL ONCOLOGY   24 巻 ( 5 ) 頁： 1188 - 1194   2017年5月

Effects of center dot OH and center dot NO radicals in the aqueous phase on H2O2 and NO2- generated in plasma-activated medium

Kurake Naoyuki, Tanaka Hiromasa, Ishikawa Kenji, Takeda Keigo, Hashizume Hiroshi, Nakamura Kae, Kajiyama Hiroaki, Kondo Takashi, Kikkawa Fumitaka, Mizuno Masaaki, Hori Masaru

JOURNAL OF PHYSICS D-APPLIED PHYSICS   50 巻 ( 15 )   2017年3月

Variable susceptibility of ovarian cancer cells to non-thermal plasma-activated medium. 査読有り

Utsumi F, Kajiyama H, Nakamura K, Tanaka H, Mizuno M, Toyokuni S, Hori M, Kikkawa F.

Oncol Rep.     2016年4月

Cell survival of glioblastoma grown in medium containing hydrogen peroxide and/or nitrite, or in plasma-activated medium. 査読有り

Kurake N, Tanaka H, Ishikawa K, Kondo T, Sekine M, Nakamura K, Kajiyama H, Kikkawa F, Mizuno M, Hori M.

Arch Biochem Biophys.     2016年1月

Effectiveness of plasma treatment on pancreatic cancer cells. 査読有り

Hattori N, Yamada S, Torii K, Takeda S, Nakamura K, Tanaka H, Kajiyama H, Kanda M, Fujii T, Nakayama G, Sugimoto H, Koike M, Nomoto S, Fujiwara M, Mizuno M, Hori M, Kodera Y.

Int J Oncol.   47 巻   頁： 1655-1662   2015年11月

Plasma-Activated Solution: Mechanism of Action, Clinical Application, and Industrialization 査読有り

Tanaka H, Mizuno M, Toyokuni S, Maruyama S, Kodera Y, Kikkawa F, Hori M.

Fukuoka Igaku Zasshi.   106 巻   頁： 71-76   2015年4月

Medicinal facilities to B16F10 melanoma cells for distant metastasis control with a supramolecular complex by DEAE-dextran-MMA copolymer/paclitaxel. 査読有り

Eshita Y, Ji RC, Onishi M, Kobayashi T, Mizuno M, Yoshida J, Kubota N, Onishi Y.

Drug Deliv Transl Res.   5 巻   頁： 38-50   2015年2月

Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration. 査読有り

Ye F, Kaneko H, Nagasaka Y, Ijima R, Nakamura K, Nagaya M, Takayama K, Kajiyama H, Senga T, Tanaka H, Mizuno M, Kikkawa F, Hori M, Terasaki H.

Sci Rep.   5 巻   頁： 7705   2015年1月

Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl-dextran-MMA graft copolymer and paclitaxel used as an artificial enzyme. 査読有り

Onishi Y, Eshita Y, Ji RC, Onishi M, Kobayashi T, Mizuno M, Yoshida J, Kubota N.

Beilstein J Nanotechnol.   ５ 巻   頁： 2293-2307   2014年12月

Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules. 査読有り

Okazaki Y, Wang Y, Tanaka H, Mizuno M, Nakamura K, Kajiyama H, Kano H, Uchida K, Kikkawa F, Hori M, Toyokuni S.

J Clin Biochem Nutr   55 巻   頁： 207-15   2014年11月

A new tumorsphere culture condition restores potentials of self-renewal and metastasis of primary neuroblastoma in a mouse neuroblastoma model. 査読有り

Cao D, Kishida S, Huang P, Mu P, Tsubota S, Mizuno M, Kadomatsu K.

PLoS One   22 巻 ( 9 ) 頁： e86813   2014年1月

Effect of indirect nonequilibrium atmospheric pressure plasma on anti-proliferative activity against chronic chemo-resistant ovarian cancer cells in vitro and in vivo. 査読有り

Utsumi F, Kajiyama H, Nakamura K, Tanaka H, Mizuno M, Ishikawa K, Kondo H, Kano H, Hori M, Kikkawa F

PLoS One.   8 巻 ( 12 ) 頁： e81576.   2013年12月

Glioblastoma Brain Tumor Cells by Down-Regulating a Survival Signaling Molecule, AKT Kinase. Plasma Medicine 査読有り

Tanaka H., Mizuno M., Ishikawa K., Nakamura K., Kajiyama H., Kano H., Kikkawa F., and Hori M.

Plasma Medicine   1 巻   頁： 265-277   2013年

Glioblastoma Brain Tumor Cells by Down-Regulating a Survival Signaling Molecule, AKT Kinase. 査読有り

Tanaka H., Mizuno M., Ishikawa K., Nakamura K., Kajiyama H., Kano H., Kikkawa F., and Hori M.

Plasma Medicine   1 巻 ( 3 ) 頁： 265-277   2013年

Significant induction of apoptosis in renal cell carcinoma cells transfected with cationic multilamellar liposomes containing the human interferon-β gene through activation of the intracellular type 1 interferon signal pathway. 査読有り

  40 巻   頁： 1441-1446   2012年

Integrated care through disease- oriented clinical care pathways: experience from Japan's regional health planning initiatives. 査読有り

Okamoto E, Miyamoto M, Hara K, Yoshida J, Muto M, Hirai A, Mizuno M, Nagata H, Yamakata D, Tanaka H.

Int J Integrated Care   11 巻   頁： 23   2011年9月

Mechanism of the Introduction of Exogenous Genes into Cultured CellsUsing DEAE-Dextran-MMA Graft Copolymer as a Non-Viral Gene Carrier.II. Its Thixotropy Property. 査読有り

  2 巻   頁： 1-8   2011年

Neurosurgical robotic system for brain tumor removal. 査読有り

Arata J, Tada Y, Kozuka H, Wada T, Saito Y, Ikedo N, Hayashi Y, Fujii M, Kajita Y, Mizuno M, Wakabayashi T, Yoshida J, Fujimoto H.

Int J Comput Assist Radiol Surg   6 巻   頁： 375-385   2010年

Development of a real-time tactile sensing system for brain tumor diagnosis. 査読有り

Tanaka Y, Yu Q, Doumoto K, Sano A, Hayashi Y, Fujii M, Kajita Y, Mizuno M, Wakabayashi T, Fujimoto H.

Int J Comput Assist Radiol Surg   ５ 巻   頁： 359-367   2010年

*Effect of sonoporation on cationic liposome-mediated IFNbeta gene therapy for metastatic hepatic tumors of murine colon cancer. 査読有り

Hayashi S, Mizuno M, Yoshida J, Nakao

Cancer Gene Ther.   16 巻 ( 8 ) 頁： 638-643   2009年

ICTを用いた脳卒中連携医療支援システムの構築

水野正明、吉田　純

日本医師会雑誌   138 巻   頁： 1369-1373   2009年

一方向型地域医療連携におけるICTの利活用

水野正明、吉田　純

ITvision   19 巻   頁： 38-39   2009年

A phase I clinical trial of interferon-beta gene therapy for high-grade glioma: novel findings from gene expression profiling and autopsy. 査読有り

Wakabayashi T, Natsume A, Hashizume Y, Fujii M, Mizuno M, Yoshida J.

J Gene Med   10 巻 ( 4 ) 頁： 329-39   2008年

A pilot study of human interferon beta gene therapy for patients with advanced melanoma by in vivo transduction using cationic liposomes. 査読有り

Matsumoto K, Kubo H, Murata H, Uhara H, Takata M, Shibata S, Yasue S, Sakakibara A, Tomita Y, Kageshita T, Kawakami Y, Mizuno M, Yoshida J, Saida T.

Jpn J Clin Oncol   38 巻 ( 12 ) 頁： 849-56   2008年

ICTを基盤にした脳卒中連携医療の実際

水野正明、吉田　純

新医療   35 巻   頁： 169-172   2008年

ICTと地域連携パス

水野正明

地域リハビリテーション   3 巻   頁： 230-231   2008年

ICTと脳卒中連携医療

水野正明、吉田　純

治療   90 巻 ( 3 ) 頁： 914-920   2008年

*Significant antitumor activity of cationic multilamellar liposomes containing human interferon-β gene in combination with 5-fluorouracil against human renal cell carcinoma. 査読有り

Yamamoto K, Mizutani Y, Nakanishi H, Fujiwara J, Ishida H, Toiyama D, Abe K, Hayashi I, Okada K, Kawauchi A, Mizuno M, Yoshida J, Miki T.

Int. J Oncol   33 巻   頁： 565-571   2008年

A Regional Health Information Exchange System for Stroke Care (Nagoya-RHIE)

Obayashi M. Kagawa M, Mizuno M, Yoshida J

IHIC   3 巻   頁： 112   2008年

*Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells 査読有り

Tsuno T, Natsume A, Katsumata S, Mizuno M, Fujita M, Osawa H, Nakahara N, Wakabayashi T, Satoh Y, Inagaki M, Yoshida J

J Neuro-Oncol   83 巻   頁： 249-258   2007年

Characteristics of DEAE-dextran-MMA graft copolymer as a nonviral gene carrier 査読有り

Onishi Y, Eshita Y, Murashita A, Mizuno M, Yoshida J

Nanomedicine   3 巻   頁： 184-191   2007年

Medical information network for neurosurgical diseases

Mizuno M, Yoshida J

No Shinkei Geka   35 巻   頁： 185-191   2007年

医療情報ネットワーク（急性期医療、回復期医療、維持期医療）

水野正明、吉田　純

脳神経外科   35 巻   頁： 185-191   2007年

連携医療支援システム

水野正明、吉田　純

脳卒中リハビリテーション連携パス   1 巻   頁： 60-64   2007年

EGFR mutations in patients with brain metastases from lung cancer: Association with the efficacy of gefitinib 査読有り

Shimato S, Mitsudomi T, Kosaka T, Yatabe Y, Wakabayashi T, Mizuno M, Nakahara N, Hatano H, Natsume A, Ishii D, Yoshida J

Neuro-Oncol   8 巻   頁： 137-144   2006年

*Combination of In Vivo Angiopoietin-1 Gene Transfer and Autologous Bone Marrow Cell Implantation for Functional Therapeutic Angiogenesis 査読有り

Kobayashi K, Kondo T, Inoue N, Aoki M, Mizuno M, Komori K, Yoshida J, Murohara T

Arterioscler Thromb Vasc Biol   26 巻   頁： 1465-1472   2006年

Gene therapy for malignant glioma 査読有り

Mizuno M, Yoshida J

Nippon Rinsho   63 巻   頁： 469-475   2005年

*IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide 査読有り

Natsume A, Ishii D, Wakabayashi T, Tsuno T, Hatano H, Mizuno M, Yoshida J

Cancer Res   65 巻   頁： 7573-7579   2005年

Susceptibility to exogenously added interferon-beta protein depends on intracellular interferon-beta mRNA level in human glioma cells 査読有り

Osawa H, Mizuno M. Hatano M, Nakahara N, Tsuno T, Kuno T, Endo M, Yoshida J

Cytokine   32 巻 ( 5 ) 頁： 240-245   2005年

2-diethylaminoethyl (DEAE)-dextran-MMA Graft Copolymer for Non-Viral Gene Delivery Vector 査読有り

Onishi Y, Eshita Y, Murashita A, Mizuno M, Yoshida J

J Appl Polym Sci   98 巻   頁： 9-14   2005年

Susceptibility to exogenously added interferon-beta protein depends on intracellular interferon-beta mRNA level in human glioma cells 査読有り

Osawa H, Mizuno M. Hatano M, Nakahara N, Tsuno T, Kuno T, Endo M, Yoshida J

Cytokine   32 巻   頁： 240-245   2005年

Structure-based design of an agonistic peptide targeting Fas 査読有り

Yoshimori A, Takasawa R, Hayakawa A, Mizuno M, Yoshida J, Tanuma S

Apoptosis   10 巻   頁： 323-329   2005年

Brain metastases from apocrine carcinoma of the scalp: case report 査読有り

1. Shimato S, Wakabayashi T, Mizuno M, Nakahara N, Hatano H, Natsume A, Ishii D, Hasegawa Y, Hyodo I, Nagasaka T, Yoshida J

J Neuro-Oncol   29 巻   頁： 1-5   2005年

IFN-beta down-regulates the expression of DNA repair gene MGMT and sensitizes resistant glioma cells to temozolomide. 査読有り

Natsume A, Ishii D, Wakabayashi T, Tsuno T, Hatano H, Mizuno M, Yoshida J

Cancer Res.   65 巻   頁： 7573-7579   2005年

Suicide gene therapy using adenovirus vector for human oral squamous carcinoma cell line in vitro. 査読有り

Yamamoto N, Hayashi Y, Kagami H, Fukui T, Fukuhara H, Tohnai I, Ueda M, Mizuno M, Yoshida J.

Nagoya J Med Sci   35 巻   頁： 185-191   2005年

Human gene therapy for malignant gliomas (glioblastoma multiforme and anaplastic astrocytoma) by in vivo transduction with human interferon beta gene using cationic liposomes 査読有り

Yoshida J, Mizuno M, Fujii M, Kajita Y, Nakahara N, Hatano M, Saito R, Nobayashi M, Wakabayashi T

Hum Gene Ther   15 巻   頁： 77-86   2004年

Growth inhibition of human pancreatic cancer cells by human interferon-beta gene combined with gemcitabine 査読有り

Endou M, Mizuno M, Nagata T, Tsukada K, Nakahara N, Tsuno T, Osawa H, Kuno T, Fujita M, Hatano M, Yoshida J

Int J Mol Med   10 巻   頁： 110-116   2004年

Aurora-B dysfunction of multinucleated giant cells in glioma detected by site-specific phosphorylated antibodies. 査読有り

Fujita M, Mizuno M, Nagasaka T, Wakabayashi T, Maeda K, Ishii D, Arima T, Kawajiri A, Inagaki M, Yoshida J

J Neurosurg   101 巻   頁： 1012-1017   2004年

Interferon-beta gene therapy for cancer: basic research to clinical application. 査読有り

Yoshida J, Mizuno M, Wakabayashi T

Cancer Sci   95 巻   頁： 858-865   2004年

Enhancement of C2-ceramide antitumor activity by small interfering RNA on X chromosome-linked inhibitor of apoptosis protein in resistant human glioma cells 査読有り

Hatano M, Mizuno M, Yoshida J

J Neurosurg   101 巻   頁： 119-127   2004年

Vaccination with tumor cell lysate-pulsed dendritic cells augments the effect of IFN-beta gene therapy for malignant glioma in an experimental mouse intracranial glioma. 査読有り

Saito R, Mizuno M, Nakahara N, Tsuno T, Kumabe T, Yoshimoto T, Yoshida J

Int J Cancer   111 巻   頁： 777-782   2004年

Two different mechanisms of apoptosis resistance observed in interferon-beta induced apoptosis of human glioma cells 査読有り

Saito R, Mizuno M, Hatano M, Kumabe T, Yoshimoto T, Yoshida J

J Neuro-Oncol   67 巻   頁： 273-280   2004年

Morphological assessment of the development of multinucleated giant cells in glioma by using mitosis-specific phosphorylated antibodies 査読有り

Maeda K, Mizuno M, Wakabayashi T, Takasu S, Nagasaka T, Inagaki M, Yoshida J

J Neurosurg   98 巻   頁： 854-859   2003年

Cell death of human oral squamous cell carcinoma cell line induced by herpes simplex virus thymidine kinase gene and ganciclovir 査読有り

Nishikawa M, Hayashi Y, Yamamoto N, Fukui T, Fukuhara H, Mitsudo K, Tohnai I, Ueda M, Mizuno M, Yoshida J

Nagoya J Med Sci   66 巻   頁： 129-137   2003年

Clinical gene therapy for brain tumors. Liposomal delivery of anticancer molecule to glioma 査読有り

Yoshida J, Mizuno M

J Neuro-Oncol   65 巻   頁： 261-267   2003年

Radioimmunoscintigraphy of intracranial glioma xenograft with a technetium-99m- labeled mouse monoclonal antibody specifically recognizing type III mutant epidermal growth factor receptor.

Takasu S, Takahashi T, Okamoto S, Oriuchi N, Nakayashiki N, Okamoto K, Muramatsu H, Hayashi T, Nakahara N, Mizuno M, Wakabayashi T, Higuchi T, Endo K, Kozaki K, Miyaishi O, Saga S, Ueda R, Yoshida J, Yoshikawa K

J Neuro-Oncol   63 巻   頁： 247-256   2003年

Growth inhibition of subcutaneous mouse melanoma and induction of natural killer cells by liposome-mediated interferon-beta gene therapy 査読有り

Ryuke Y, Mizuno M, Natsume A, Suzuki O, Nobayashi M, Kageshita T, Matsumoto K, Saida T, Yoshida J

Melanoma Res   13 巻   頁： 349-356   2003年

Apoptotic DNA endonuclease (DNase-gamma) gene transfer induces cell death accompanying DNA fragmentation in human glioma cells 査読有り

Saito R, Mizuno M, Kumabe T, Yoshimoto T, Tanuma S, Yoshida J

J Neuro-Oncol   63 巻   頁： 25-31   2003年

Improvement of transduction efficiency of recombinant adenovirus vector conjugated with cationic liposome for human oral squamous cell carcinoma cell lines 査読有り

Fukuhara H, Hayashi Y, Yamamoto N, Fukui T, Nishikawa M, Mitsudo K, Tohnai I, Ueda M, Mizuno M, Yoshida J

Oral Oncol   39 巻   頁： 601-609   2003年

Brain tumors 査読有り

Hatano M, Mizuno M, Yoshida J

Gan To Kagaku Ryoho   30 巻   頁： 455-459   2003年

Caspase activation in neuronal and glial apoptosis following spinal cord injury in mice 査読有り

Takagi T, Takayasu M, Mizuno M, Yoshimoto M, Yoshida J

Neurol Med Chir   43 巻   頁： 20-29   2003年

Antitumor Effect of an Experimental Intracranial Human Glioma by Adeno-associated Virus Vector Containing the Human Interferon-β Gene 査読有り

Yoshida J, Mizuno M, Nakahara N and Colosi P

Jpn J Cancer Res   93 巻   頁： 223-228   2002年

Cationic liposomes conjugation to recombinant adenoviral vectors containing herpes simplex virus thymidine kinase gene followed by ganciclovir treatment reduces viral antigenicity and maintains antitumor activity in mouse subcutaneous glioma model 査読有り

Mizuno M, Ryuke Y, Yoshida J

Cancer Gene Ther   9 巻   頁： 825-829   2002年

Processof apoptosis induced by TNF-α in murine fibroblast Ltk- cell: Continuous observation with video enhanced contrast microscopy 査読有り

Okamoto K, Mizuno M, Nakahara N, Natsume A, Yoshida J, Mori T, Hori S, Kobayashi H

Apoptosis   7 巻   頁： 77-86   2002年

Dendritic cells pulsed with tumor extract-cationic liposomes complex increase the induction of cytotoxic T lymphocytes in mouse brain tumor 査読有り

Aoki H, Mizuno M, Natsume A, Tsugawa T, Tsujimura K, Takahashi T, Yoshida J

Cancer Immunol Immunother   50 巻   頁： 463-468   2002年

Rat glioma cell death induced by cationic liposome-mediated transfer of the herpes simplex virus thymidine kinase gene followed by ganciclovir treatment 査読有り

Yoshida T, Mizuno M, Taniguchi K, Nakayashiki N, Wakabayashi T, Yoshida J

J Surgical Oncol   30 巻   頁： 1-7   2001年

Combined effects of Adeno-associated virus vector and a herpes simplex virus mutant as neoplastic therapy 査読有り

Kasuya H, Mizuno M, Yoshida J, Nishiyama Y, Nomoto S, Nakano A

  74 巻   頁： 214-218   2000年

Transduction Efficiency of Adenoviral Vectors Into Human Glioma Cells Increased By Association With Cationic Liposomes 査読有り

Ryuke Y, Mizuno M, Natsume A, and Yoshida J

Neurol Med Chir   40 巻   頁： 256-260   2000年

IFN-β gene therapy inducessystemic antitumor immunity against malignant glioma. 査読有り

Natsume A, Tsujimura K, Mizuno M, Takahashi T, and Yoshida J

J Neuro-oncol   47 巻   頁： 117-124   2000年

Cationic liposome conjugation to recombinant adenoviral vector reduces viral antigenicity 査読有り

Natsume A, Mizuno M, Ryuke Y, Yoshida J.

Jpn. J. Cancer Res   91 巻   頁： 363-367   2000年

Inhibitation of nuclear factor-κB activation confers sensitivity to tumor necrosis factor-α by impairment of cell cycle progression in human glioma cells 査読有り

Otsuka G, Nagaya T, Saito K, Mizuno M, Yoshida J, Seo H,

Cancer Res   59 巻   頁： 4446-4452   1999年

Antitumor effect and cellular immunity activation by murine interferon-β gene transfer against intracerebral glioma in mouse 査読有り

Natsume A., Mizuno M., Yoshida J.

Gene Therapy   6 巻   頁： 1626-1633   1999年

Imumnohistochemical staining of DNA topoisomerase (]G0002[)α in human glinne.

Journal of Neurosurgery   91 巻   頁： 477-482   1999年

Synergism between mild hyperthermia and interferon-β gene expression

Cancer letters   139 巻   頁： 153-158   1999年

Adeno-associated virus vectors containing the herpes simplex virus-thymidine kinase gene cause complete regression of intracerebrally implanted human gliomas on mice

Jpn J Cancer Res   89 巻   頁： 76-80   1998年

Growth inhibition of experimental glioma by human interferon-β superinduced by cationic liposomes entrapping polyinosilic : polycytidilic acid

Neurol Med Chir(Tokyo)   38 巻   頁： 469-474   1998年

Effect of human interferon-β gene transfer upon human glioma transplanted into nude mouse brain involues induced natural killer cells

Cancer Immunology Immunotherapy   47 巻   頁： 227-232   1998年

Video-enhanced microscopic visualization of apoptotic cell death caused by anti-Fas antibody in living human glioma cells

Brain Tumor Pathol   15 巻   頁： 19-21   1998年

脳腫瘍の遺伝子治療

Annual Review 神経     頁： 135-140   1997年

Augmentation of anti-Fas antibody-mediated apoptosis on human glioma cells by liposomes associated with the antibody

J Neuro-Oncology   35 巻   頁： 7-11   1997年

Antitumor activity of recombinant human tumor necrosis factor-α(rH-TNFα)and liposome-entrapped rH-TNFα

Neurologica medico-chirurgica   37 巻   頁： 719-722   1997年

Enzyme immunoassay of glioma cell tenascin secretion and augmentation by tumor necrosis factor-α

Neurologica medico-chirurgica   37 巻   頁： 392-398   1997年

Tumor necrosis factor-α gene transfer augments anti-Fas antibody mediated apoptosis in human glioma cells

Jpn J Cancer Res   8 巻   頁： 543-547   1996年

モノクローナル抗体結合リポソームによるターゲティング療法へのアプローチ

日本DDS学会誌   11 巻   頁： 385-391   1996年

Repeated exposure to cationic immunoliposomes activates effective gene transfer to human glioma cells

Neurologia medico-chirurgica   36 巻   頁： 141-144   1996年

Gene therapy against an experimental glioma using adeno-associated virus vectors

Gene Therapy   3 巻   頁： 957-964   1996年

Cytolysis of malignant glioma cells by lymphokine-actirated killer cells combined with anti-CD3-antiglioma bifunctional antibody and tumor necrosis factor-α

J. Surgical Oncol.   62 巻   頁： 177-182   1996年

ヒトグリオーマ細胞における抗Fas 抗体誘導アポトーシスの修飾

神経免疫研究   9 巻   頁： 153-157   1996年

New approach for the treatment of medulloblastoma by transfection with glial fibrillary acidic protein gene

Surgical Oncol   5 巻   頁： 69-75   1996年

グリオ-マ細胞の増殖におけるサイトカインの関与;特に遺伝子導入により誘導されるヒト型インタ-フェロンの抗腫瘍効果について

  8 巻 ( 3 ) 頁： 95-98   1995年

脳腫瘍に対する遺伝子治療の開発

組織培養   21 巻   頁： 356-358   1995年

Growth inhibition of intracerebral rat glioma by transfection-induced human interferon-β

J Surgical Oncology   55 巻   頁： 105-109   1995年

Reinforced cytotoxixity of lymphokine-activated killer cells toward glioma cells by transfection of the killer cells with the γ-interferon gene.

Jpn J Cancer Res   86 巻   頁： 95-100   1995年

脳腫瘍に対するサイトカイン遺伝子治療

蛋白質核酸酵素 遺伝子治療     頁： 2709-2712   1995年

脳腫瘍の遺伝子治療(動物実験)

実験医学別冊バイオマニュアルUPシリ-ズ遺伝子治療の基礎技術     頁： 191-194   1995年

遺伝子治療DDSとしてのDNA/liposome

日本DDS学会誌   44 巻   頁： 399-403   1995年

Inhibition of hepatitis B virus replication by interferon-β produced in situ by gene delivery.

Environ Med   39 巻   頁： 33-36   1995年

Simple preparation and characterization of cationic liposomes associated with a monoclonal antibody against glioma-associated antigen (immunoliposomes).

J Liposome Res   5 巻   頁： 981-995   1995年

サイトカイン遺伝子導入LAKによる癌免疫療法

血液、腫瘍科   28 巻   頁： 376-380   1994年

Growth inhibition of subcutaneously transplanted human glioma by transfection-induced tumor necrosis factor-α and augmentation of the effect by γ-interferon.

J Neuro-Oncol   22 巻   頁： 221-225   1994年

Simple method to prepare cationic multulamellar liposomes for efficient transfection of human interferon-β gene to human glioma cells

J Neuro-Oncol   19 巻   頁： 269-274   1994年

Retroviral transfer of herpes simplex thymidine kinase gene into glioma cells causes targeting of gancyclovir cytotoxic effect.

Neurologia medico-chirurgica   34 巻   頁： 339-344   1994年

Liposomal transfection of human γ-interferon gene into human glioma cells and adoptive immunotherapy using lymphokine-activated killer cells.

J Neurosurg   80 巻   頁： 510-514   1994年

遺伝子導入用ベクタ-の種類と特徴(4)リポソ-ムを用いた遺伝子導入

造血因子   5 巻   頁： 457-460   1994年

Transfection-induced tumor necrosis factor-α increases the susceptibility of human glioma cells to lysis by lymphokine-acctivated killer cells : continuous expression of intercellular adhesion molecule-1 on the glioma cells.

Jpn J Cancer Res   85 巻   頁： 750-755   1994年

悪性神経膠腫に対する遺伝子組換えヒト腫瘍壊死因子(PAC-4D)の前期第(]G0002[)相臨床試験

薬理と治療   22 巻 ( Suppl.9 ) 頁： 291-310   1994年

Radioimmunolocalization of human brain tumor : Fundamental studies with indium-111 labeled monoclonal antibody G-22.

Brain Tumor Pathology   11 巻 ( 2 ) 頁： 177-180   1994年

脳腫瘍の新しい治療法:サイトカイン遺伝子療法

  12 巻   頁： 682-683   1994年

Interferon-β endogenously produced by intratumoral injection of cationic liposome-encapsulated gene : Cytocidal effect on glioma transplanted into mude mouse brain.

Biochem Mol Biol Int   32 巻   頁： 167-172   1994年

Reinforced cytotoxicity of lymphokine-activated killer cells toward glioma cells by transfection with the tumor necrosis facter-α gene.

J Neurosurg   78 巻   頁： 252-256   1993年

Alternation of tumor associated cell surface antigenic expression (G-22 related antigen) with cytokines in vitro and in vivo.

Neuroimmunological research (神経免疫研究)   5 巻   頁： 120-122   1993年

Tumor-specific binding of radiolabeled G-22 monoclonal antibody in glioma patients.

Neurologia medico-chirurgica (Tokyo)   32 巻   頁： 125-129   1992年

Cytotoxicity of human β-interferon produced human glioma cells transfected with its gene by means of liposomes.

Biocheistry inernational   28 巻   頁： 1055-1061   1992年

Effectiveness of interferon-β,ACNU,and radiation therapy in pediatric patients with brainstem glioma.

Neurologia medico-chirurgica (Tokyo)   32 巻   頁： 942-946   1992年

Growth inhibition of glioma cells by liposome-mediated cell transfection with tumor necrosis factor-α gene. Its enhancement by prior γ-interferon treatment.

Neurologia medico-chirurgica (Tokyo)   32 巻   頁： 873-876   1992年

Clinical effect of intra-arterial tumor necrosis factor-α for malignant glioma.

J Neurosurg   77 巻   頁： 78-83   1992年

脳腫瘍治療に於けるG-CSFの有効性

  63 巻   頁： 490-491   1992年

脳腫瘍治療におけるG-CSFの有効性

  6 巻   頁： 490-491   1992年

Antitumor effect of endogenous human β-interferon on malignant glioma and augmentation of the effect by tumor necrosis factor-α.

J Clin Biochem Nutr   12 巻   頁： 153-160   1992年

モノクロ-ナル抗体結合リポソ-ムの抗腫瘍効果

  10 巻   頁： 84-88   1992年

Cytotoxicity of human β-and γ-interferon produced simultaneously in glioma cells transfected with interferon genes.

J Clin Biochem Nutr   13 巻   頁： 1-6   1992年

モノクロ-ナル抗体結合リポソ-ムの抗腫瘍効果.

カレントテラピ-   10 巻 ( 6 ) 頁： 84-88   1992年

G-CSFヒト悪性glioma細胞の増殖に及ぼす影響特にTNF-αの細胞増殖抑制効果の増強効果について

  63 巻   頁： 429-430   1992年

ラット脳腫瘍移植モデルに対するTNF-α動注療法の検討、動物実験MRIによる検索

神経免疫研究   5 巻   頁： 218-221   1992年

脳内出血による高次機能障害に対するCT誘導下定位的血腫除去術の有効性

社会保険医学雑誌   32 巻   頁： 1-5   1992年

サイトカインによる脳腫瘍関連抗原発現の変化

神経免疫研究   5 巻   頁： 120-122   1992年

悪性脳腫瘍に対するtargeting療法の開発

日本DDS学会誌   25 巻   頁： 331-339   1992年

悪性脳腫瘍に対するインタ-フェロン遺伝子療法の開発

脳神経外科   20 巻   頁： 547-551   1992年

Section of human β-interferon into the cystic fluid f glioma transfected with the interferon gene.

J Clin Biochem Nutr   11 巻   頁： .123-128   1991年

Superinduction of cytotoxic interferon-β in glioma cells.

Neurologia medico-chirurgica (Tokyo)   31 巻   頁： 485-489   1991年

rH-TNF-αの悪性脳腫瘍に対する動注療法:特にCTにおける経時的腫瘍造影効果の変化について

  5 巻   頁： 478-482   1991年

¹¹¹In標識モノクロ-ナル抗体G-22による脳腫瘍の画像診断への応用

神経免疫研究   4 巻   頁： 276-280   1991年

Intracranial metastasis of a choroid plexus papilloma originating in the cerebellopontine angle region : A case report.

Surg Neurol   36 巻   頁： 54-58   1991年

Growth inhibition of glioma cells transfected with the human β-interferon gene by liposomes coupled with a monoclonal antibody. 査読有り

Mizuno M, Yoshida J, Sugita K, Inoue I, Seo H, Hayashi Y, Koshizaka T, Yagi K

Cancer Res   50 巻   頁： 7826-7829   1990年

Radioimaging of human glioma xenografts with ¹²³I labeled monoclonal antibody G-22 against glioma-associated antigen.

J Neuro-Oncol   8 巻   頁： 221-229   1990年

Glowth inhibition of glioma cells of diferent cell lines by human interferon-β produced in the cells transfected with its gene by means of lipsomes.

J Clin Biochem Nutr   9 巻   頁： 73-77   1990年

悪性脳腫瘍に対するインタ-フェロン遺伝子療法

神経免疫研究   3 巻   頁： 153-158   1990年

Glowth inhibition of glioma cells transfected with the human β-interferon gene by liposomes coupled with a monoclonal antibody.

Cancer Res   50 巻   頁： 7826-7829   1990年

¹³¹I標識抗gliomaモノクロ-ナル抗体G-22の臨床応用:画像診断及びタ-ゲット療法の試み

神経免疫研究   3 巻   頁： 119-122   1990年

両側性網膜芽細胞腫の治療15年後に発生した頭蓋内線維肉腫、Cisplatin,VP-16併用化学療法の有効性

脳神経外科   17 巻   頁： 653-657   1989年

CDDPとEtoposide併用療法が奏功した頭蓋内Germinoma2症例

癌と化学療法   16 巻   頁： 3457-3460   1989年

ヒトglioma細胞におけるHuIFN-β,IFGF-(]G0002[)の合成分泌能

神経免疫研究   2 巻   頁： 159-164   1989年