論文 - 邊見 久
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Inhibition of glycine cleavage system by pyridoxine 5 '-phosphate causes synthetic lethality in glyA yggS and serA yggS in Escherichia coli 査読有り 国際共著
Ito Tomokazu, Hori Ran, Hemmi Hisashi, Downs Diana M., Yoshimura Tohru
MOLECULAR MICROBIOLOGY 113 巻 ( 1 ) 頁： 270 - 284 2020年1月
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Construction of an artificial biosynthetic pathway for hyperextended archaeal membrane lipids in the bacterium Escherichia coli 査読有り
Yoshida Ryo, Hemmi Hisashi
SYNTHETIC BIOLOGY 5 巻 ( 1 ) 頁： ysaa018 2020年
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A heteromeric cis-prenyltransferase is responsible for the biosynthesis of glycosyl carrier lipids in Methanosarcina mazei 査読有り
Emi Koh-ichi, Sompiyachoke Kitty, Okada Miyako, Hemmi Hisashi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 520 巻 ( 2 ) 頁： 291 - 296 2019年12月
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Conserved Pyridoxal 5 '-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5 '-Phosphate in Escherichia coli 査読有り 国際共著
Ito Tomokazu, Yamamoto Kana, Hori Ran, Yamauchi Ayako, Downs Diana M., Hemmi Hisashi, Yoshimura Tohru
APPLIED AND ENVIRONMENTAL MICROBIOLOGY 85 巻 ( 11 ) 2019年6月
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Conversion of Mevalonate 3-Kinase into 5-Phosphomevalonate 3-Kinase by Single Amino Acid Mutations 査読有り
Motoyama Kento, Sobue Fumiaki, Kawaide Hiroshi, Yoshimura Tohru, Hemmi Hisashi
APPLIED AND ENVIRONMENTAL MICROBIOLOGY 85 巻 ( 9 ) 2019年5月
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Modified mevalonate pathway of the archaeon <i>Aeropyrum pernix</i> proceeds via <i>trans</i>-anhydromevalonate 5-phosphate. 査読有り
Hayakawa H, Motoyama K, Sobue F, Ito T, Kawaide H, Yoshimura T, Hemmi H
Proceedings of the National Academy of Sciences of the United States of America 115 巻 ( 40 ) 頁： 10034-10039 2018年9月
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D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum 査読有り
Ito Tomokazu, Hamauchi Natsuki, Hagi Taisuke, Morohashi Naoya, Hemmi Hisashi, Sato Yukie G., Saito Tamao, Yoshimura Tohru
FRONTIERS IN MICROBIOLOGY 9 巻 頁： 784 2018年4月
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Production of Ophthalmic Acid Using Engineered Escherichia coli 査読有り
Ito Tomokazu, Tokoro Maiko, Hori Ran, Hemmi Hisashi, Yoshimura Tohru
APPLIED AND ENVIRONMENTAL MICROBIOLOGY 84 巻 ( 7 ) 2018年4月
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Biosynthetic machinery for C-25,C-25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix 査読有り
Yoshida Ryo, Yoshimura Tohru, Hemmi Hisashi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 497 巻 ( 1 ) 頁： 87-92 2018年2月
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Utilization of an intermediate of the methylerythritol phosphate pathway, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate, as the prenyl donor substrate for various prenyltransferases 査読有り
Hayashi Yoshifumi, Ito Tomokazu, Yoshimura Tohru, Hemmi Hisashi
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 82 巻 ( 6 ) 頁： 993-1002 2018年
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Occurrence of the (2R,3S) -Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus 査読有り
Ito Tomokazu, Yu Zhuoer, Yoshino Issei, Hirozawa Yurina, Yamamoto Kana, Shinoda Kiyotugu, Watanabe Akira, Hemmi Hisashi, Asada Yasuhiko, Yoshimura Tohru
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 65 巻 ( 30 ) 頁： 6131-6139 2017年8月
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Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae 査読有り
Hayakawa Hajime, Sobue Fumiaki, Motoyama Kento, Yoshimura Tohru, Hemmi Hisashi
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 487 巻 ( 3 ) 頁： 702-708 2017年6月
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A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase 査読有り
Motoyama Kento, Unno Hideaki, Hattori Ai, Takaoka Tomohiro, Ishikita Hiroshi, Kawaide Hiroshi, Yoshimura Tohru, Hemmi Hisashi
JOURNAL OF BIOLOGICAL CHEMISTRY 292 巻 ( 6 ) 頁： 2457-2469 2017年2月
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メバロン酸経路の多様性 招待有り
邊見 久
バイオサイエンスとインダストリー 74 巻 ( 1 ) 頁： 15-20 2016年
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大腸菌をプラットフォームとしたアーキア膜脂質生合成研究 招待有り
邊見 久
酵素工学ニュース ( 76 ) 頁： 11-15 2016年
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A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation 査読有り
Ogawa, T., Emi, K., Koga, K., Yoshimura, T. & Hemmi, H.
FEBS Journal 283 巻 頁： 2369-2383 2016年
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Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5'-phosphate-binding protein YggS 査読有り
Ito, T., Yamauchi, A., Hemmi, H. & Yoshimura, T.
Journal of Bioscience and Bioengineering 122 巻 頁： 689-693 2016年
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A new member of MocR/GabR-type PLP-binding regulator of D-alanyl-D-alanine ligase in Brevibacillus brevis 査読有り
Takenaka, T., Ito, T., Miyahara, I., Hemmi, H. & Yoshimura T.
FEBS Journal 282 巻 頁： 4201-4217 2015年
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Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator 査読有り
Okuda, K., Kato, S., Ito, T., Shiraki, S., Kawase, Y., Goto, M., Kawashima, S., Hemmi, H., Fukada H. & Yoshimura T.
Molecular Microbiology 95 巻 ( 2 ) 頁： 245-257 2015年
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Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator 査読有り
Okuda, K., Ito, T., Goto, M., Takenaka, T., Hemmi, H. & Yoshimura T.
Journal of Biochemistry 158 巻 ( 3 ) 頁： 225-234 2015年